A2M	DB00626	alpha-2-macroglobulin	approved	Bacitracin	CC[C@H](C)[C@H](N)C1=N[C@@H](CS1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@H]1CCCCNC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@H](CC2=CNC=N2)NC(=O)[C@@H](CC2=CC=CC=C2)NC(=O)[C@@H](NC(=O)[C@@H](CCCN)NC1=O)[C@@H](C)CC
AADAT	DB00114	aminoadipate aminotransferase	nutraceutical	Pyridoxal Phosphate	CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O
AADAT	DB00142	aminoadipate aminotransferase	approved; nutraceutical	L-Glutamic Acid	N[C@@H](CCC(O)=O)C(O)=O
AADAT	DB00123	aminoadipate aminotransferase	approved; nutraceutical	L-Lysine	NCCCC[C@H](N)C(O)=O
AANAT	DB00360	aralkylamine N-acetyltransferase	approved; investigational	Tetrahydrobiopterin	CC(O)C(O)C1CNC2=C(N1)C(=O)N=C(N)N2
AANAT	DB00150	aralkylamine N-acetyltransferase	approved; nutraceutical	L-Tryptophan	N[C@@H](CC1=CNC2=CC=CC=C12)C(O)=O
AASS	DB00142	aminoadipate-semialdehyde synthase	approved; nutraceutical	L-Glutamic Acid	N[C@@H](CCC(O)=O)C(O)=O
AASS	DB00157	aminoadipate-semialdehyde synthase	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
AASS	DB02338	aminoadipate-semialdehyde synthase	experimental	Nadph Dihydro-Nicotinamide-Adenine-Dinucleotidephosphate	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@@H](CO[P@](O)(=O)O[P@@](O)(=O)OC[C@@H]2O[C@H]([C@H](OP(O)(O)=O)[C@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@H]1O
AASS	DB04207	aminoadipate-semialdehyde synthase	experimental	N-(5-Amino-5-Carboxypentyl)Glutamic Acid	N[C@@H](CCCCN[C@@H](CCC(O)=O)C(O)=O)C(O)=O
AASS	DB00123	aminoadipate-semialdehyde synthase	approved; nutraceutical	L-Lysine	NCCCC[C@H](N)C(O)=O
ABAT	DB00114	4-aminobutyrate aminotransferase	nutraceutical	Pyridoxal Phosphate	CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O
ABAT	DB00119	4-aminobutyrate aminotransferase	approved; nutraceutical	Pyruvic acid	CC(=O)C(O)=O
ABAT	DB00142	4-aminobutyrate aminotransferase	approved; nutraceutical	L-Glutamic Acid	N[C@@H](CCC(O)=O)C(O)=O
ABAT	DB00160	4-aminobutyrate aminotransferase	approved; nutraceutical	L-Alanine	C[C@H](N)C(O)=O
ABAT	DB00313	4-aminobutyrate aminotransferase	approved; investigational	Valproic Acid	CCCC(CCC)C(O)=O
ABAT	DB00780	4-aminobutyrate aminotransferase	approved	Phenelzine	NNCCC1=CC=CC=C1
ABAT	DB01080	4-aminobutyrate aminotransferase	approved	Vigabatrin	NC(CCC(O)=O)C=C
ABAT	DB01699	4-aminobutyrate aminotransferase	experimental	(4e)-4-Aminohex-4-Enoic Acid	C\C=C(/N)CCC(O)=O
ABAT	DB04235	4-aminobutyrate aminotransferase	experimental	4-Amino Hexanoic Acid	CC[C@H](N)CCC(O)=O
ABCA1	DB00171	ATP-binding cassette, sub-family A (ABC1), member 1	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
ABCA1	DB01016	ATP-binding cassette, sub-family A (ABC1), member 1	approved	Glyburide	COC1=C(C=C(Cl)C=C1)C(=O)NCCC1=CC=C(C=C1)S(=O)(=O)NC(=O)NC1CCCCC1
ABCA1	DB01599	ATP-binding cassette, sub-family A (ABC1), member 1	approved	Probucol	CC(C)(SC1=CC(=C(O)C(=C1)C(C)(C)C)C(C)(C)C)SC1=CC(=C(O)C(=C1)C(C)(C)C)C(C)(C)C
ABCA1	DB01039	ATP-binding cassette, sub-family A (ABC1), member 1	approved	Fenofibrate	CC(C)OC(=O)C(C)(C)OC1=CC=C(C=C1)C(=O)C1=CC=C(Cl)C=C1
ABCA1	DB01076	ATP-binding cassette, sub-family A (ABC1), member 1	approved	Atorvastatin	CC(C)C1=C(C(=O)NC2=CC=CC=C2)C(=C(N1CC[C@@H](O)C[C@@H](O)CC(O)=O)C1=CC=C(F)C=C1)C1=CC=CC=C1
ABCA1	DB00755	ATP-binding cassette, sub-family A (ABC1), member 1	approved; nutraceutical; investigational	Tretinoin	CC(C=CC1=C(C)CCCC1(C)C)=CC=CC(C)=CC(O)=O
ABCA1	DB01095	ATP-binding cassette, sub-family A (ABC1), member 1	approved	Fluvastatin	CC(C)N1C(\C=C\[C@H](O)C[C@H](O)CC(O)=O)=C(C2=CC=C(F)C=C2)C2=CC=CC=C12
ABCA1	DB00412	ATP-binding cassette, sub-family A (ABC1), member 1	approved; investigational	Rosiglitazone	CN(CCOC1=CC=C(CC2SC(=O)NC2=O)C=C1)C1=CC=CC=N1
ABCA1	DB00264	ATP-binding cassette, sub-family A (ABC1), member 1	approved; investigational	Metoprolol	COCCC1=CC=C(OCC(O)CNC(C)C)C=C1
ABCB1	DB00171	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
ABCB1	DB00778	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Roxithromycin	CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@@H]2O[C@@H](C)[C@H](O)[C@](C)(OC)C2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@H](N(C)C)[C@H]2O)[C@](C)(O)C[C@@H](C)\C(=N\OCOCCOC)[C@H](C)[C@@H](O)[C@@]1(O)C
ABCB1	DB04877	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Voacamine	CC[C@H]1C[C@@H]2CN3CCC4=C(NC5=CC([C@H]6C[C@@H]7C([C@@H](CC8=C6NC6=CC=CC=C86)N(C)C\C7=C\C)C(=O)OC)=C(OC)C=C45)[C@](C2)([C@H]13)C(=O)OC
ABCB1	DB00694	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Daunorubicin	COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3O[C@H]3C[C@H](N)[C@H](O)[C@H](C)O3)C(C)=O)C(O)=C1C2=O
ABCB1	DB00997	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Doxorubicin	COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3O[C@H]3C[C@H](N)[C@H](O)[C@H](C)O3)C(=O)CO)C(O)=C1C2=O
ABCB1	DB01229	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Paclitaxel	CC(=O)O[C@@H]1C2=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)C3=CC=CC=C3)[C@@H]3[C@@]4(CO[C@@H]4C[C@H](O)[C@@]3(C)C1=O)OC(C)=O)C2(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)C1=CC=CC=C1)C1=CC=CC=C1
ABCB1	DB00485	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Dicloxacillin	CC1=C(C(=O)N[C@H]2[C@H]3SC(C)(C)[C@@H](N3C2=O)C(O)=O)C(=NO1)C1=C(Cl)C=CC=C1Cl
ABCB1	DB00932	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Tipranavir	CCC[C@@]1(CCC2=CC=CC=C2)CC(=O)C([C@H](CC)C2=CC(NS(=O)(=O)C3=NC=C(C=C3)C(F)(F)F)=CC=C2)=C(O)O1
ABCB1	DB00201	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Caffeine	CN1C=NC2=C1C(=O)N(C)C(=O)N2C
ABCB1	DB00514	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Dextromethorphan	COC1=CC2=C(C[C@H]3[C@H]4CCCC[C@@]24CCN3C)C=C1
ABCB1	DB00762	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Irinotecan	CCC1=C2CN3C(=CC4=C(COC(=O)[C@]4(O)CC)C3=O)C2=NC2=C1C=C(OC(=O)N1CCC(CC1)N1CCCCC1)C=C2
ABCB1	DB00198	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Oseltamivir	CCOC(=O)C1=C[C@@H](OC(CC)CC)[C@H](NC(C)=O)[C@@H](N)C1
ABCB1	DB00709	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Lamivudine	NC1=NC(=O)N(C=C1)[C@@H]1CS[C@H](CO)O1
ABCB1	DB00526	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Oxaliplatin	O=C1O[Pt]2(N[C@@H]3CCCC[C@H]3N2)OC1=O
ABCB1	DB01042	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Melphalan	NC(CC1=CC=C(C=C1)N(CCCl)CCCl)C(O)=O
ABCB1	DB00571	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Propranolol	CC(C)NCC(O)COC1=CC=CC2=CC=CC=C12
ABCB1	DB00143	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
ABCB1	DB00381	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Amlodipine	CCOC(=O)C1=C(COCCN)NC(C)=C(C1C1=CC=CC=C1Cl)C(=O)OC
ABCB1	DB00497	ATP-binding cassette, sub-family B (MDR/TAP), member 1	illicit; approved; investigational	Oxycodone	COC1=C2O[C@H]3C(=O)CC[C@@]4(O)[C@H]5CC(C=C1)=C2[C@@]34CCN5C
ABCB1	DB00308	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Ibutilide	CCCCCCCN(CC)CCCC(O)C1=CC=C(NS(C)(=O)=O)C=C1
ABCB1	DB00318	ATP-binding cassette, sub-family B (MDR/TAP), member 1	illicit; approved	Codeine	COC1=C2O[C@H]3[C@@H](O)C=C[C@H]4[C@H]5CC(C=C1)=C2[C@@]34CCN5C
ABCB1	DB00215	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Citalopram	CN(C)CCCC1(OCC2=C1C=CC(=C2)C#N)C1=CC=C(F)C=C1
ABCB1	DB00207	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Azithromycin	CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)C(C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C)(O)C[C@@H](C)CN(C)[C@H](C)[C@@H](O)[C@]1(C)O
ABCB1	DB01258	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Aliskiren	COCCCOC1=C(OC)C=CC(C[C@@H](C[C@H](N)[C@@H](O)C[C@@H](C(C)C)C(=O)NCC(C)(C)C(N)=O)C(C)C)=C1
ABCB1	DB00736	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Esomeprazole	COC1=CC2=C(C=C1)N=C(N2)S(=O)CC1=NC=C(C)C(OC)=C1C
ABCB1	DB00338	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Omeprazole	COC1=CC2=C(C=C1)N=C(N2)S(=O)CC1=NC=C(C)C(OC)=C1C
ABCB1	DB00213	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Pantoprazole	COC1=C(OC)C(CS(=O)C2=NC3=C(N2)C=C(OC(F)F)C=C3)=NC=C1
ABCB1	DB00158	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; nutraceutical	Folic Acid	NC1=NC(=O)C2=NC(CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)=CN=C2N1
ABCB1	DB00495	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Zidovudine	CC1=CN([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2)C(=O)NC1=O
ABCB1	DB00819	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Acetazolamide	CC(=O)NC1=NN=C(S1)S(N)(=O)=O
ABCB1	DB00829	ATP-binding cassette, sub-family B (MDR/TAP), member 1	illicit; approved	Diazepam	CN1C2=C(C=C(Cl)C=C2)C(=NCC1=O)C1=CC=CC=C1
ABCB1	DB00593	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Ethosuximide	CCC1(C)CC(=O)NC1=O
ABCB1	DB00754	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Ethotoin	CCN1C(=O)NC(C1=O)C1=CC=CC=C1
ABCB1	DB01595	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Nitrazepam	[O-][N+](=O)C1=CC2=C(NC(=O)CN=C2C2=CC=CC=C2)C=C1
ABCB1	DB00909	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Zonisamide	NS(=O)(=O)CC1=NOC2=CC=CC=C12
ABCB1	DB00349	ATP-binding cassette, sub-family B (MDR/TAP), member 1	illicit; approved; investigational	Clobazam	CN1C2=C(C=C(Cl)C=C2)N(C2=CC=CC=C2)C(=O)CC1=O
ABCB1	DB01068	ATP-binding cassette, sub-family B (MDR/TAP), member 1	illicit; approved	Clonazepam	[O-][N+](=O)C1=CC2=C(NC(=O)CN=C2C2=CC=CC=C2Cl)C=C1
ABCB1	DB00273	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Topiramate	CC1(C)O[C@@H]2CO[C@@]3(COS(N)(=O)=O)OC(C)(C)O[C@H]3[C@@H]2O1
ABCB1	DB01080	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Vigabatrin	NC(CCC(O)=O)C=C
ABCB1	DB01177	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Idarubicin	C[C@@H]1O[C@H](C[C@H](N)[C@@H]1O)O[C@H]1C[C@@](O)(CC2=C1C(O)=C1C(=O)C3=CC=CC=C3C(=O)C1=C2O)C(C)=O
ABCB1	DB01175	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Escitalopram	CN(C)CCC[C@]1(OCC2=C1C=CC(=C2)C#N)C1=CC=C(F)C=C1
ABCB1	DB01248	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Docetaxel	CC(=O)O[C@@]12CO[C@@H]1C[C@H](O)[C@]1(C)[C@@H]2[C@H](OC(=O)C2=CC=CC=C2)[C@]2(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C3=CC=CC=C3)C(C)=C([C@@H](O)C1=O)C2(C)C
ABCB1	DB04630	ATP-binding cassette, sub-family B (MDR/TAP), member 1	experimental	Aldosterone	C[C@]12CCC(=O)C=C1CC[C@H]1[C@@H]3CC[C@H](C(=O)CO)[C@]3(C[C@H](O)[C@H]21)C=O
ABCB1	DB00523	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Alitretinoin	C\C(\C=C\C1=C(C)CCCC1(C)C)=C\C=C\C(\C)=C\C(O)=O
ABCB1	DB01118	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Amiodarone	CCCCC1=C(C(=O)C2=CC(I)=C(OCCN(CC)CC)C(I)=C2)C2=CC=CC=C2O1
ABCB1	DB00321	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Amitriptyline	CN(C)CCC=C1C2=CC=CC=C2CCC2=CC=CC=C12
ABCB1	DB00701	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Amprenavir	CC(C)CN(C[C@@H](O)[C@H](CC1=CC=CC=C1)NC(=O)O[C@H]1CCOC1)S(=O)(=O)C1=CC=C(N)C=C1
ABCB1	DB00637	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; withdrawn	Astemizole	COC1=CC=C(CCN2CCC(CC2)NC2=NC3=CC=CC=C3N2CC2=CC=C(F)C=C2)C=C1
ABCB1	DB01244	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Bepridil	CC(C)COCC(CN(CC1=CC=CC=C1)C1=CC=CC=C1)N1CCCC1
ABCB1	DB01200	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Bromocriptine	CC(C)C[C@@H]1N2C(=O)[C@](NC(=O)[C@H]3CN(C)[C@@H]4CC5=C(Br)NC6=CC=CC(=C56)C4=C3)(O[C@@]2(O)[C@@H]2CCCN2C1=O)C(C)C
ABCB1	DB01136	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Carvedilol	COC1=CC=CC=C1OCCNCC(O)COC1=CC=CC2=C1C1=CC=CC=C1N2
ABCB1	DB00291	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Chlorambucil	OC(=O)CCCC1=CC=C(C=C1)N(CCCl)CCCl
ABCB1	DB00477	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Chlorpromazine	CN(C)CCCN1C2=CC=CC=C2SC2=C1C=C(Cl)C=C2
ABCB1	DB00501	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Cimetidine	C\N=C(\NCCSCC1=C(C)NC=N1)NC#N
ABCB1	DB00515	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Cisplatin	N[Pt](N)(Cl)Cl
ABCB1	DB01211	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Clarithromycin	CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@@H]2C[C@](C)(OC)[C@H](O)[C@@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@@](C)(C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O)OC
ABCB1	DB00257	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Clotrimazole	ClC1=CC=CC=C1C(N1C=CN=C1)(C1=CC=CC=C1)C1=CC=CC=C1
ABCB1	DB00970	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Dactinomycin	CC(C)C1NC(=O)C(NC(=O)C2=C3N=C4C(OC3=C(C)C=C2)=C(C)C(=O)C(N)=C4C(=O)NC2C(C)OC(=O)C(C(C)C)N(C)C(=O)CN(C)C(=O)C3CCCN3C(=O)C(NC2=O)C(C)C)C(C)OC(=O)C(C(C)C)N(C)C(=O)CN(C)C(=O)C2CCCN2C1=O
ABCB1	DB00975	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Dipyridamole	OCCN(CCO)C1=NC2=C(N=C(N=C2N2CCCCC2)N(CCO)CCO)C(=N1)N1CCCCC1
ABCB1	DB00822	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Disulfiram	CCN(CC)C(=S)SSC(=S)N(CC)CC
ABCB1	DB01184	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Domperidone	ClC1=CC2=C(C=C1)N(C1CCN(CCCN3C(=O)NC4=CC=CC=C34)CC1)C(=O)N2
ABCB1	DB00254	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Doxycycline	C[C@@H]1[C@H]2[C@H](O)[C@H]3[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]3(O)C(O)=C2C(=O)C2=C1C=CC=C2O
ABCB1	DB01023	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Felodipine	CCOC(=O)C1=C(C)NC(C)=C(C1C1=C(Cl)C(Cl)=CC=C1)C(=O)OC
ABCB1	DB00741	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Hydrocortisone	C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
ABCB1	DB01005	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Hydroxyurea	NC(=O)NO
ABCB1	DB00224	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Indinavir	CC(C)(C)NC(=O)[C@@H]1CN(CC2=CN=CC=C2)CCN1C[C@@H](O)C[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]1[C@H](O)CC2=CC=CC=C12
ABCB1	DB00602	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Ivermectin	CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@H]1[C@H](C)O[C@H](C[C@@H]1OC)O[C@H]1[C@@H](C)\C=C\C=C2/CO[C@@H]3[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]4C[C@@H](C\C=C1/C)O[C@@]1(CC[C@H](C)[C@@H](C(C)C)O1)C4)[C@]23O.CC[C@@H](C)[C@H]1O[C@@]2(CC[C@@H]1C)O[C@@H]1C\C=C(C)\[C@@H](O[C@@H]3O[C@@H](C)[C@H](O[C@@H]4O[C@@H](C)[C@H](O)[C@@H](OC)C4)[C@@H](OC)C3)[C@@H](C)\C=C\C=C3/CO[C@@H]4[C@H](O)C(C)=C[C@@H](C(=O)O[C@@H](C1)C2)[C@]34O
ABCB1	DB01137	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Levofloxacin	C[C@H]1COC2=C3N1C=C(C(O)=O)C(=O)C3=CC(F)=C2N1CCN(C)CC1
ABCB1	DB00836	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Loperamide	CN(C)C(=O)C(CCN1CCC(O)(CC1)C1=CC=C(Cl)C=C1)(C1=CC=CC=C1)C1=CC=CC=C1
ABCB1	DB00678	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Losartan	CCCCC1=NC(Cl)=C(CO)N1CC1=CC=C(C=C1)C1=CC=CC=C1C1=NNN=N1
ABCB1	DB00959	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Methylprednisolone	C[C@H]1C[C@H]2[C@@H]3CC[C@](O)(C(=O)CO)[C@@]3(C)C[C@H](O)[C@@H]2[C@@]2(C)C=CC(=O)C=C12
ABCB1	DB00305	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Mitomycin	CO[C@]12[C@H]3N[C@H]3CN1C1=C([C@H]2COC(N)=O)C(=O)C(N)=C(C)C1=O
ABCB1	DB01204	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Mitoxantrone	OCCNCCNC1=C2C(=O)C3=C(O)C=CC(O)=C3C(=O)C2=C(NCCNCCO)C=C1
ABCB1	DB00622	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Nicardipine	COC(=O)C1=C(C)NC(C)=C(C1C1=CC(=CC=C1)[N+]([O-])=O)C(=O)OCCN(C)CC1=CC=CC=C1
ABCB1	DB01115	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Nifedipine	COC(=O)C1=C(C)NC(C)=C(C1C1=CC=CC=C1[N+]([O-])=O)C(=O)OC
ABCB1	DB01054	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Nitrendipine	CCOC(=O)C1=C(C)NC(C)=C(C1C1=CC(=CC=C1)[N+]([O-])=O)C(=O)OC
ABCB1	DB00904	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Ondansetron	CN1C2=C(C3=CC=CC=C13)C(=O)C(CN1C=CN=C1C)CC2
ABCB1	DB00715	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Paroxetine	FC1=CC=C(C=C1)[C@@H]1CCNC[C@H]1COC1=CC2=C(OCO2)C=C1
ABCB1	DB00652	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Pentazocine	C[C@H]1[C@H]2CC3=CC=C(O)C=C3[C@]1(C)CCN2CC=C(C)C
ABCB1	DB01032	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Probenecid	CCCN(CCC)S(=O)(=O)C1=CC=C(C=C1)C(O)=O
ABCB1	DB00396	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Progesterone	CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C
ABCB1	DB00420	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Promazine	CN(C)CCCN1C2=CC=CC=C2SC2=CC=CC=C12
ABCB1	DB01182	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Propafenone	CCCNCC(O)COC1=CC=CC=C1C(=O)CCC1=CC=CC=C1
ABCB1	DB00908	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Quinidine	COC1=CC2=C(C=CN=C2C=C1)[C@H](O)[C@H]1C[C@@H]2CCN1C[C@@H]2C=C
ABCB1	DB00468	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Quinine	COC1=CC2=C(C=CN=C2C=C1)[C@@H](O)[C@@H]1CC2CCN1C[C@@H]2C=C
ABCB1	DB00863	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Ranitidine	CN\C(NCCSCC1=CC=C(CN(C)C)O1)=C/[N+]([O-])=O
ABCB1	DB00206	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Reserpine	CO[C@H]1[C@@H](C[C@@H]2CN3CCC4=C(NC5=C4C=CC(OC)=C5)[C@H]3C[C@@H]2[C@@H]1C(=O)OC)OC(=O)C1=CC(OC)=C(OC)C(OC)=C1
ABCB1	DB01104	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Sertraline	CN[C@H]1CC[C@@H](C2=CC(Cl)=C(Cl)C=C2)C2=CC=CC=C12
ABCB1	DB01208	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Sparfloxacin	C[C@H]1CN(C[C@@H](C)N1)C1=C(F)C(N)=C2C(=O)C(=CN(C3CC3)C2=C1F)C(O)=O
ABCB1	DB00675	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Tamoxifen	CC\C(=C(/C1=CC=CC=C1)C1=CC=C(OCCN(C)C)C=C1)C1=CC=CC=C1
ABCB1	DB00444	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Teniposide	COC1=CC(=CC(OC)=C1O)[C@H]1[C@@H]2[C@H](COC2=O)[C@H](O[C@@H]2O[C@@H]3COC(O[C@H]3[C@H](O)[C@H]2O)C2=CC=CS2)C2=CC3=C(OCO3)C=C12
ABCB1	DB00342	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; withdrawn	Terfenadine	CC(C)(C)C1=CC=C(C=C1)C(O)CCCN1CCC(CC1)C(O)(C1=CC=CC=C1)C1=CC=CC=C1
ABCB1	DB04844	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Tetrabenazine	COC1=C(OC)C=C2C3CC(=O)C(CC(C)C)CN3CCC2=C1
ABCB1	DB00759	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Tetracycline	CN(C)[C@H]1[C@@H]2C[C@H]3C(=C(O)[C@]2(O)C(=O)C(C(N)=O)=C1O)C(=O)C1=C(O)C=CC=C1[C@@]3(C)O
ABCB1	DB01030	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Topotecan	CC[C@@]1(O)C(=O)OCC2=C1C=C1N(CC3=CC4=C(C=CC(O)=C4CN(C)C)N=C13)C2=O
ABCB1	DB00755	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; nutraceutical; investigational	Tretinoin	CC(C=CC1=C(C)CCCC1(C)C)=CC=CC(C)=CC(O)=O
ABCB1	DB01339	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Vecuronium	CC(=O)O[C@H]1[C@H](C[C@H]2[C@@H]3CC[C@H]4C[C@H](OC(C)=O)[C@H](C[C@]4(C)[C@H]3CC[C@]12C)N1CCCCC1)[N+]1(C)CCCCC1
ABCB1	DB01392	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Yohimbine	COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCC4=C(NC5=CC=CC=C45)[C@@H]3C[C@H]12
ABCB1	DB00363	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Clozapine	CN1CCN(CC1)C1=NC2=CC(Cl)=CC=C2NC2=CC=CC=C12
ABCB1	DB00445	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Epirubicin	COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3O[C@H]3C[C@H](N)[C@@H](O)[C@H](C)O3)C(=O)CO)C(O)=C1C2=O
ABCB1	DB00285	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Venlafaxine	COC1=CC=C(C=C1)C(CN(C)C)C1(O)CCCCC1
ABCB1	DB00683	ATP-binding cassette, sub-family B (MDR/TAP), member 1	illicit; approved	Midazolam	CC1=NC=C2CN=C(C3=CC=CC=C3F)C3=C(C=CC(Cl)=C3)N12
ABCB1	DB00317	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Gefitinib	COC1=C(OCCCN2CCOCC2)C=C2C(NC3=CC(Cl)=C(F)C=C3)=NC=NC2=C1
ABCB1	DB00993	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Azathioprine	CN1C=NC(=C1SC1=NC=NC2=C1NC=N2)[N+]([O-])=O
ABCB1	DB00661	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Verapamil	COC1=C(OC)C=C(CCN(C)CCCC(C#N)(C(C)C)C2=CC(OC)=C(OC)C=C2)C=C1
ABCB1	DB00570	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Vinblastine	CC[C@]1(O)C[C@H]2CN(C1)CCC1=C(NC3=CC=CC=C13)[C@@](C2)(C(=O)OC)C1=CC2=C(C=C1OC)N(C)[C@@H]1[C@]22CCN3CC=C[C@](CC)([C@@H]23)[C@@H](OC(C)=O)[C@]1(O)C(=O)OC
ABCB1	DB00530	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Erlotinib	COCCOC1=C(OCCOC)C=C2C(NC3=CC=CC(=C3)C#C)=NC=NC2=C1
ABCB1	DB01026	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Ketoconazole	CC(=O)N1CCN(CC1)C1=CC=C(OC[C@@H]2CO[C@](CN3C=CN=C3)(O2)C2=C(Cl)C=C(Cl)C=C2)C=C1
ABCB1	DB00540	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Nortriptyline	CNCCC=C1C2=CC=CC=C2CCC2=CC=CC=C12
ABCB1	DB00333	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Methadone	CCC(=O)C(CC(C)N(C)C)(C1=CC=CC=C1)C1=CC=CC=C1
ABCB1	DB01452	ATP-binding cassette, sub-family B (MDR/TAP), member 1	illicit; experimental	Heroin	CN1CC[C@]23[C@H]4OC5=C(OC(C)=O)C=CC(C[C@@H]1[C@@H]2C=C[C@@H]4OC(C)=O)=C35
ABCB1	DB01076	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Atorvastatin	CC(C)C1=C(C(=O)NC2=CC=CC=C2)C(=C(N1CC[C@@H](O)C[C@@H](O)CC(O)=O)C1=CC=C(F)C=C1)C1=CC=CC=C1
ABCB1	DB00439	ATP-binding cassette, sub-family B (MDR/TAP), member 1	withdrawn	Cerivastatin	COCC1=C(C2=CC=C(F)C=C2)C(\C=C\[C@@H](O)C[C@@H](O)CC(O)=O)=C(C(C)C)N=C1C(C)C
ABCB1	DB00343	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Diltiazem	COC1=CC=C(C=C1)[C@@H]1SC2=CC=CC=C2N(CCN(C)C)C(=O)[C@@H]1OC(C)=O
ABCB1	DB01095	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Fluvastatin	CC(C)N1C(\C=C\[C@H](O)C[C@H](O)CC(O)=O)=C(C2=CC=C(F)C=C2)C2=CC=CC=C12
ABCB1	DB01241	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Gemfibrozil	CC1=CC(OCCCC(C)(C)C(O)=O)=C(C)C=C1
ABCB1	DB01167	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Itraconazole	CCC(C)N1N=CN(C1=O)C1=CC=C(C=C1)N1CCN(CC1)C1=CC=C(OC[C@H]2CO[C@@](CN3C=NC=N3)(O2)C2=C(Cl)C=C(Cl)C=C2)C=C1
ABCB1	DB00227	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Lovastatin	CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12
ABCB1	DB00175	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Pravastatin	CC[C@H](C)C(=O)O[C@H]1C[C@H](O)C=C2C=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC(O)=O)[C@@H]12
ABCB1	DB00503	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Ritonavir	CC(C)[C@H](NC(=O)N(C)CC1=CSC(=N1)C(C)C)C(=O)N[C@H](C[C@H](O)[C@H](CC1=CC=CC=C1)NC(=O)OCC1=CN=CS1)CC1=CC=CC=C1
ABCB1	DB01098	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Rosuvastatin	CC(C)C1=NC(=NC(C2=CC=C(F)C=C2)=C1\C=C\[C@H](O)C[C@@H](O)CC(O)=O)N(C)S(=O)(=O)C
ABCB1	DB00996	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Gabapentin	NCC1(CC(O)=O)CCCCC1
ABCB1	DB00555	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Lamotrigine	NC1=NC(N)=C(N=N1)C1=C(Cl)C(Cl)=CC=C1
ABCB1	DB01202	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Levetiracetam	CC[C@@H](N1CCCC1=O)C(N)=O
ABCB1	DB01174	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Phenobarbital	CCC1(C(=O)NC(=O)NC1=O)C1=CC=CC=C1
ABCB1	DB00472	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Fluoxetine	CNCCC(OC1=CC=C(C=C1)C(F)(F)F)C1=CC=CC=C1
ABCB1	DB00252	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Phenytoin	O=C1NC(=O)C(N1)(C1=CC=CC=C1)C1=CC=CC=C1
ABCB1	DB00877	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Sirolimus	CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1O
ABCB1	DB01169	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Arsenic trioxide	O1[As]2O[As]1O2
ABCB1	DB00950	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Fexofenadine	CC(C)(C(O)=O)C1=CC=C(C=C1)C(O)CCCN1CCC(CC1)C(O)(C1=CC=CC=C1)C1=CC=CC=C1
ABCB1	DB00316	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Acetaminophen	CC(=O)NC1=CC=C(O)C=C1
ABCB1	DB00295	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Morphine	CN1CC[C@]23[C@H]4OC5=C(O)C=CC(C[C@@H]1[C@@H]2C=C[C@@H]4O)=C35
ABCB1	DB00813	ATP-binding cassette, sub-family B (MDR/TAP), member 1	illicit; approved; investigational	Fentanyl	CCC(=O)N(C1CCN(CCC2=CC=CC=C2)CC1)C1=CC=CC=C1
ABCB1	DB00624	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Testosterone	C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CC[C@@H]2O
ABCB1	DB00352	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Thioguanine	NC1=NC(=S)C2=C(N1)N=CN2
ABCB1	DB00196	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Fluconazole	OC(CN1C=NC=N1)(CN1C=NC=N1)C1=C(F)C=C(F)C=C1
ABCB1	DB00958	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Carboplatin	N.N.O=C1O[Pt]OC(=O)C11CCC1
ABCB1	DB00199	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Erythromycin	CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O
ABCB1	DB00448	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Lansoprazole	CC1=C(OCC(F)(F)F)C=CN=C1CS(=O)C1=NC2=CC=CC=C2N1
ABCB1	DB01222	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Budesonide	CCC[C@H]1O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO
ABCB1	DB00641	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Simvastatin	CCC(C)(C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CCC3C[C@@H](O)CC(=O)O3)[C@@H]12
ABCB1	DB00889	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Granisetron	CN1N=C(C(=O)NC2CC3CCCC(C2)N3C)C2=CC=CC=C12
ABCB1	DB00619	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Imatinib	CN1CCN(CC2=CC=C(C=C2)C(=O)NC2=CC(NC3=NC=CC(=N3)C3=CN=CC=C3)=C(C)C=C2)CC1
ABCB1	DB00564	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Carbamazepine	NC(=O)N1C2=CC=CC=C2C=CC2=CC=CC=C12
ABCB1	DB00987	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Cytarabine	NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O
ABCB1	DB01234	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Dexamethasone	C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
ABCB1	DB00773	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Etoposide	COC1=CC(=CC(OC)=C1O)[C@H]1[C@@H]2[C@H](COC2=O)[C@H](O[C@@H]2O[C@@H]3CO[C@@H](C)O[C@H]3[C@H](O)[C@H]2O)C2=CC3=C(OCO3)C=C12
ABCB1	DB00650	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Leucovorin	NC1=NC(=O)C2=C(NCC(CNC3=CC=C(C=C3)C(=O)N[C@H](CCC(O)=O)C(O)=O)N2C=O)N1
ABCB1	DB01033	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Mercaptopurine	S=C1N=CNC2=C1NC=N2
ABCB1	DB00563	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
ABCB1	DB00635	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Prednisone	C[C@]12CC(=O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
ABCB1	DB00541	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Vincristine	CC[C@]1(O)C[C@H]2CN(C1)CCC1=C(NC3=CC=CC=C13)[C@@](C2)(C(=O)OC)C1=C(OC)C=C2N(C=O)[C@@H]3[C@]4(CCN5CC=C[C@](CC)([C@@H]45)[C@@H](OC(C)=O)[C@]3(O)C(=O)OC)C2=C1
ABCB1	DB00973	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Ezetimibe	O[C@@H](CC[C@@H]1[C@H](N(C1=O)C1=CC=C(F)C=C1)C1=CC=C(O)C=C1)C1=CC=C(F)C=C1
ABCB1	DB01045	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Rifampin	CO[C@H]1\C=C\O[C@@]2(C)OC3=C(C)C(O)=C4C(O)=C(NC(=O)\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@H](O)[C@H](C)[C@H](OC(C)=O)[C@@H]1C)C(\C=N\N1CCN(C)CC1)=C(O)C4=C3C2=O
ABCB1	DB00758	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; nutraceutical	Clopidogrel	COC(=O)[C@@H](N1CCC2=C(C1)C=CS2)C1=CC=CC=C1Cl
ABCB1	DB00864	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Tacrolimus	CO[C@@H]1C[C@@H](CC[C@H]1O)\C=C(/C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H]([C@H](C[C@H]2C)OC)[C@H](C[C@@H](C)C\C(C)=C\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]1C)OC
ABCB1	DB00358	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Mefloquine	OC(C1CCCCN1)C1=CC(=NC2=C1C=CC=C2C(F)(F)F)C(F)(F)F
ABCB1	DB01072	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Atazanavir	COC(=O)N[C@H](C(=O)N[C@@H](CC1=CC=CC=C1)[C@@H](O)CN(CC1=CC=C(C=C1)C1=CC=CC=N1)NC(=O)[C@@H](NC(=O)OC)C(C)(C)C)C(C)(C)C
ABCB1	DB01601	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Lopinavir	CC(C)[C@H](N1CCCNC1=O)C(=O)N[C@H](C[C@H](O)[C@H](CC1=CC=CC=C1)NC(=O)COC1=C(C)C=CC=C1C)CC1=CC=CC=C1
ABCB1	DB01232	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Saquinavir	CC(C)(C)NC(=O)[C@@H]1CC2CCCCC2CN1C[C@@H](O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CC(N)=O)NC(=O)C1=NC2=CC=CC=C2C=C1
ABCB1	DB00531	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Cyclophosphamide	ClCCN(CCCl)P1(=O)NCCCO1
ABCB1	DB00734	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Risperidone	CC1=C(CCN2CCC(CC2)C2=NOC3=C2C=CC(F)=C3)C(=O)N2CCCCC2=N1
ABCB1	DB00625	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Efavirenz	FC(F)(F)[C@]1(OC(=O)NC2=C1C=C(Cl)C=C2)C#CC1CC1
ABCB1	DB00441	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Gemcitabine	NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](CO)[C@@H](O)C1(F)F
ABCB1	DB00220	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Nelfinavir	CC1=C(C=CC=C1O)C(=O)N[C@@H](CSC1=CC=CC=C1)[C@H](O)CN1C[C@H]2CCCC[C@H]2C[C@H]1C(=O)NC(C)(C)C
ABCB1	DB00238	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Nevirapine	CC1=C2NC(=O)C3=C(N=CC=C3)N(C3CC3)C2=NC=C1
ABCB1	DB00313	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Valproic Acid	CCCC(CCC)C(O)=O
ABCB1	DB00390	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Digoxin	C[C@H]1O[C@H](C[C@H](O)[C@@H]1O)O[C@H]1[C@@H](O)C[C@H](O[C@H]2[C@@H](O)C[C@H](O[C@H]3CC[C@@]4(C)[C@H](CC[C@@H]5[C@@H]4C[C@@H](O)[C@]4(C)C(CC[C@]54O)C4=CC(=O)OC4)C3)O[C@@H]2C)O[C@@H]1C
ABCB1	DB01394	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Colchicine	COC1=C(OC)C(OC)=C2C(CC[C@H](NC(C)=O)C3=CC(=O)C(OC)=CC=C23)=C1
ABCB1	DB00544	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Fluorouracil	FC1=CNC(=O)NC1=O
ABCB1	DB00682	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Warfarin	CC(=O)CC(C1=CC=CC=C1)C1=C(O)OC2=CC=CC=C2C1=O
ABCB1	DB00334	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Olanzapine	CN1CCN(CC1)C1=C2C=C(C)SC2=NC2=CC=CC=C2N1
ABCB1	DB01016	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Glyburide	COC1=C(C=C(Cl)C=C1)C(=O)NCCC1=CC=C(C=C1)S(=O)(=O)NC(=O)NC1CCCCC1
ABCB1	DB00412	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Rosiglitazone	CN(CCOC1=CC=C(CC2SC(=O)NC2=O)C=C1)C1=CC=CC=N1
ABCB1	DB00331	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Metformin	CN(C)C(=N)NC(N)=N
ABCB1	DB00688	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Mycophenolate mofetil	COC1=C(C\C=C(/C)CCC(=O)OCCN2CCOCC2)C(O)=C2C(=O)OCC2=C1C
ABCB1	DB02587	ATP-binding cassette, sub-family B (MDR/TAP), member 1	experimental	Forskolin	CC(=O)O[C@H]1[C@@H](O)[C@H]2C(C)(C)CC[C@H](O)[C@]2(C)[C@@]2(O)C(=O)C[C@@](C)(O[C@]12C)C=C
ABCB1	DB00457	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Prazosin	COC1=C(OC)C=C2C(N)=NC(=NC2=C1)N1CCN(CC1)C(=O)C1=CC=CO1
ABCB1	DB01048	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved; investigational	Abacavir	NC1=NC2=C(N=CN2[C@@H]2C[C@H](CO)C=C2)C(NC2CC2)=N1
ABCB1	DB00451	ATP-binding cassette, sub-family B (MDR/TAP), member 1	approved	Levothyroxine	N[C@@H](CC1=CC(I)=C(OC2=CC(I)=C(O)C(I)=C2)C(I)=C1)C(O)=O
ABCB11	DB00171	ATP-binding cassette, sub-family B (MDR/TAP), member 11	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
ABCB11	DB01016	ATP-binding cassette, sub-family B (MDR/TAP), member 11	approved	Glyburide	COC1=C(C=C(Cl)C=C1)C(=O)NCCC1=CC=C(C=C1)S(=O)(=O)NC(=O)NC1CCCCC1
ABCB11	DB00143	ATP-binding cassette, sub-family B (MDR/TAP), member 11	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
ABCB11	DB00175	ATP-binding cassette, sub-family B (MDR/TAP), member 11	approved	Pravastatin	CC[C@H](C)C(=O)O[C@H]1C[C@H](O)C=C2C=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC(O)=O)[C@@H]12
ABCB11	DB00145	ATP-binding cassette, sub-family B (MDR/TAP), member 11	approved; nutraceutical	Glycine	NCC(O)=O
ABCB4	DB00143	ATP-binding cassette, sub-family B (MDR/TAP), member 4	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
ABCB4	DB00997	ATP-binding cassette, sub-family B (MDR/TAP), member 4	approved; investigational	Doxorubicin	COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3O[C@H]3C[C@H](N)[C@H](O)[C@H](C)O3)C(=O)CO)C(O)=C1C2=O
ABCB4	DB00382	ATP-binding cassette, sub-family B (MDR/TAP), member 4	approved	Tacrine	NC1=C2CCCCC2=NC2=CC=CC=C12
ABCC3	DB00709	ATP-binding cassette, sub-family C (CFTR/MRP), member 3	approved; investigational	Lamivudine	NC1=NC(=O)N(C=C1)[C@@H]1CS[C@H](CO)O1
ABCC3	DB00143	ATP-binding cassette, sub-family C (CFTR/MRP), member 3	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
ABCC3	DB00544	ATP-binding cassette, sub-family C (CFTR/MRP), member 3	approved	Fluorouracil	FC1=CNC(=O)NC1=O
ABCC3	DB00145	ATP-binding cassette, sub-family C (CFTR/MRP), member 3	approved; nutraceutical	Glycine	NCC(O)=O
ABCC3	DB00515	ATP-binding cassette, sub-family C (CFTR/MRP), member 3	approved	Cisplatin	N[Pt](N)(Cl)Cl
ABCC3	DB00441	ATP-binding cassette, sub-family C (CFTR/MRP), member 3	approved	Gemcitabine	NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](CO)[C@@H](O)C1(F)F
ABCC3	DB00158	ATP-binding cassette, sub-family C (CFTR/MRP), member 3	approved; nutraceutical	Folic Acid	NC1=NC(=O)C2=NC(CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)=CN=C2N1
ABCC3	DB00650	ATP-binding cassette, sub-family C (CFTR/MRP), member 3	approved	Leucovorin	NC1=NC(=O)C2=C(NCC(CNC3=CC=C(C=C3)C(=O)N[C@H](CCC(O)=O)C(O)=O)N2C=O)N1
ABCC3	DB00563	ATP-binding cassette, sub-family C (CFTR/MRP), member 3	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
ABCC3	DB00773	ATP-binding cassette, sub-family C (CFTR/MRP), member 3	approved	Etoposide	COC1=CC(=CC(OC)=C1O)[C@H]1[C@@H]2[C@H](COC2=O)[C@H](O[C@@H]2O[C@@H]3CO[C@@H](C)O[C@H]3[C@H](O)[C@H]2O)C2=CC3=C(OCO3)C=C12
ABCC3	DB00444	ATP-binding cassette, sub-family C (CFTR/MRP), member 3	approved	Teniposide	COC1=CC(=CC(OC)=C1O)[C@H]1[C@@H]2[C@H](COC2=O)[C@H](O[C@@H]2O[C@@H]3COC(O[C@H]3[C@H](O)[C@H]2O)C2=CC=CS2)C2=CC3=C(OCO3)C=C12
ABCC3	DB00762	ATP-binding cassette, sub-family C (CFTR/MRP), member 3	approved; investigational	Irinotecan	CCC1=C2CN3C(=CC4=C(COC(=O)[C@]4(O)CC)C3=O)C2=NC2=C1C=C(OC(=O)N1CCC(CC1)N1CCCCC1)C=C2
ABCC3	DB00987	ATP-binding cassette, sub-family C (CFTR/MRP), member 3	approved; investigational	Cytarabine	NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O
ABCC3	DB00741	ATP-binding cassette, sub-family C (CFTR/MRP), member 3	approved	Hydrocortisone	C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
ABCC5	DB00544	ATP-binding cassette, sub-family C (CFTR/MRP), member 5	approved	Fluorouracil	FC1=CNC(=O)NC1=O
ABCC5	DB01248	ATP-binding cassette, sub-family C (CFTR/MRP), member 5	approved; investigational	Docetaxel	CC(=O)O[C@@]12CO[C@@H]1C[C@H](O)[C@]1(C)[C@@H]2[C@H](OC(=O)C2=CC=CC=C2)[C@]2(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C3=CC=CC=C3)C(C)=C([C@@H](O)C1=O)C2(C)C
ABCC5	DB00515	ATP-binding cassette, sub-family C (CFTR/MRP), member 5	approved	Cisplatin	N[Pt](N)(Cl)Cl
ABCC5	DB00441	ATP-binding cassette, sub-family C (CFTR/MRP), member 5	approved	Gemcitabine	NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](CO)[C@@H](O)C1(F)F
ABCC5	DB00203	ATP-binding cassette, sub-family C (CFTR/MRP), member 5	approved; investigational	Sildenafil	CCCC1=NN(C)C2=C1NC(=NC2=O)C1=C(OCC)C=CC(=C1)S(=O)(=O)N1CCN(C)CC1
ABCC5	DB01033	ATP-binding cassette, sub-family C (CFTR/MRP), member 5	approved	Mercaptopurine	S=C1N=CNC2=C1NC=N2
ABCC5	DB00352	ATP-binding cassette, sub-family C (CFTR/MRP), member 5	approved	Thioguanine	NC1=NC(=S)C2=C(N1)N=CN2
ABCC5	DB00762	ATP-binding cassette, sub-family C (CFTR/MRP), member 5	approved; investigational	Irinotecan	CCC1=C2CN3C(=CC4=C(COC(=O)[C@]4(O)CC)C3=O)C2=NC2=C1C=C(OC(=O)N1CCC(CC1)N1CCCCC1)C=C2
ABCC5	DB00987	ATP-binding cassette, sub-family C (CFTR/MRP), member 5	approved; investigational	Cytarabine	NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O
ABCC5	DB00741	ATP-binding cassette, sub-family C (CFTR/MRP), member 5	approved	Hydrocortisone	C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
ABCC5	DB00650	ATP-binding cassette, sub-family C (CFTR/MRP), member 5	approved	Leucovorin	NC1=NC(=O)C2=C(NCC(CNC3=CC=C(C=C3)C(=O)N[C@H](CCC(O)=O)C(O)=O)N2C=O)N1
ABCC5	DB00563	ATP-binding cassette, sub-family C (CFTR/MRP), member 5	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
ABCC5	DB01004	ATP-binding cassette, sub-family C (CFTR/MRP), member 5	approved; investigational	Ganciclovir	NC1=NC(=O)C2=C(N1)N(COC(CO)CO)C=N2
ABCC5	DB00495	ATP-binding cassette, sub-family C (CFTR/MRP), member 5	approved	Zidovudine	CC1=CN([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2)C(=O)NC1=O
ABCC8	DB00171	ATP-binding cassette, sub-family C (CFTR/MRP), member 8	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
ABCC8	DB00222	ATP-binding cassette, sub-family C (CFTR/MRP), member 8	approved	Glimepiride	CCC1=C(C)CN(C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC2CCC(C)CC2)C1=O
ABCC8	DB00672	ATP-binding cassette, sub-family C (CFTR/MRP), member 8	approved	Chlorpropamide	CCCNC(=O)NS(=O)(=O)C1=CC=C(Cl)C=C1
ABCC8	DB00731	ATP-binding cassette, sub-family C (CFTR/MRP), member 8	approved; investigational	Nateglinide	CC(C)C1CC[C@@H](CC1)C(=O)N[C@H](CC1=CC=CC=C1)C(O)=O
ABCC8	DB00912	ATP-binding cassette, sub-family C (CFTR/MRP), member 8	approved; investigational	Repaglinide	CCOC1=C(C=CC(CC(=O)N[C@@H](CC(C)C)C2=CC=CC=C2N2CCCCC2)=C1)C(O)=O
ABCC8	DB01016	ATP-binding cassette, sub-family C (CFTR/MRP), member 8	approved	Glyburide	COC1=C(C=C(Cl)C=C1)C(=O)NCCC1=CC=C(C=C1)S(=O)(=O)NC(=O)NC1CCCCC1
ABCC8	DB01067	ATP-binding cassette, sub-family C (CFTR/MRP), member 8	approved	Glipizide	CC1=CN=C(C=N1)C(=O)NCCC1=CC=C(C=C1)S(=O)(=O)NC(=O)NC1CCCCC1
ABCC8	DB01120	ATP-binding cassette, sub-family C (CFTR/MRP), member 8	approved	Gliclazide	CC1=CC=C(C=C1)S(=O)(=O)NC(=O)NN1CC2CCCC2C1
ABCC8	DB01124	ATP-binding cassette, sub-family C (CFTR/MRP), member 8	approved	Tolbutamide	CCCCNC(=O)NS(=O)(=O)C1=CC=C(C)C=C1
ABCC8	DB01251	ATP-binding cassette, sub-family C (CFTR/MRP), member 8	approved	Gliquidone	COC1=CC2=C(C=C1)C(C)(C)C(=O)N(CCC1=CC=C(C=C1)S(=O)(=O)NC(=O)NC1CCCCC1)C2=O
ABCC8	DB01252	ATP-binding cassette, sub-family C (CFTR/MRP), member 8	approved; investigational	Mitiglinide	OC(=O)C(CC(=O)N1CC2CCCCC2C1)CC1=CC=CC=C1
ABCC8	DB01289	ATP-binding cassette, sub-family C (CFTR/MRP), member 8	approved	Glisoxepide	CC1=CC(=NO1)C(=O)NCCC1=CC=C(C=C1)S(=O)(=O)NC(=O)NN1CCCCCC1
ABCC8	DB01382	ATP-binding cassette, sub-family C (CFTR/MRP), member 8	approved	Glycodiazine	COCCOC1=CN=C(NS(=O)(=O)C2=CC=CC=C2)N=C1
ABCC8	DB01248	ATP-binding cassette, sub-family C (CFTR/MRP), member 8	approved; investigational	Docetaxel	CC(=O)O[C@@]12CO[C@@H]1C[C@H](O)[C@]1(C)[C@@H]2[C@H](OC(=O)C2=CC=CC=C2)[C@]2(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C3=CC=CC=C3)C(C)=C([C@@H](O)C1=O)C2(C)C
ABCC8	DB00515	ATP-binding cassette, sub-family C (CFTR/MRP), member 8	approved	Cisplatin	N[Pt](N)(Cl)Cl
ABCC8	DB00441	ATP-binding cassette, sub-family C (CFTR/MRP), member 8	approved	Gemcitabine	NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](CO)[C@@H](O)C1(F)F
ABCC8	DB01119	ATP-binding cassette, sub-family C (CFTR/MRP), member 8	approved	Diazoxide	CC1=NS(=O)(=O)C2=C(N1)C=CC(Cl)=C2
ABCD1	DB01907	ATP-binding cassette, sub-family D (ALD), member 1	experimental	Nicotinamide-Adenine-Dinucleotide	NC(=O)C1=CC=C[N+](=C1)[C@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@@H]1O
ABCG1	DB00171	ATP-binding cassette, sub-family G (WHITE), member 1	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
ABCG1	DB00762	ATP-binding cassette, sub-family G (WHITE), member 1	approved; investigational	Irinotecan	CCC1=C2CN3C(=CC4=C(COC(=O)[C@]4(O)CC)C3=O)C2=NC2=C1C=C(OC(=O)N1CCC(CC1)N1CCCCC1)C=C2
ABCG2	DB00709	ATP-binding cassette, sub-family G (WHITE), member 2	approved; investigational	Lamivudine	NC1=NC(=O)N(C=C1)[C@@H]1CS[C@H](CO)O1
ABCG2	DB00390	ATP-binding cassette, sub-family G (WHITE), member 2	approved	Digoxin	C[C@H]1O[C@H](C[C@H](O)[C@@H]1O)O[C@H]1[C@@H](O)C[C@H](O[C@H]2[C@@H](O)C[C@H](O[C@H]3CC[C@@]4(C)[C@H](CC[C@@H]5[C@@H]4C[C@@H](O)[C@]4(C)C(CC[C@]54O)C4=CC(=O)OC4)C3)O[C@@H]2C)O[C@@H]1C
ABCG2	DB00997	ATP-binding cassette, sub-family G (WHITE), member 2	approved; investigational	Doxorubicin	COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3O[C@H]3C[C@H](N)[C@H](O)[C@H](C)O3)C(=O)CO)C(O)=C1C2=O
ABCG2	DB00987	ATP-binding cassette, sub-family G (WHITE), member 2	approved; investigational	Cytarabine	NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O
ABCG2	DB00694	ATP-binding cassette, sub-family G (WHITE), member 2	approved	Daunorubicin	COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3O[C@H]3C[C@H](N)[C@H](O)[C@H](C)O3)C(C)=O)C(O)=C1C2=O
ABCG2	DB00773	ATP-binding cassette, sub-family G (WHITE), member 2	approved	Etoposide	COC1=CC(=CC(OC)=C1O)[C@H]1[C@@H]2[C@H](COC2=O)[C@H](O[C@@H]2O[C@@H]3CO[C@@H](C)O[C@H]3[C@H](O)[C@H]2O)C2=CC3=C(OCO3)C=C12
ABCG2	DB01204	ATP-binding cassette, sub-family G (WHITE), member 2	approved; investigational	Mitoxantrone	OCCNCCNC1=C2C(=O)C3=C(O)C=CC(O)=C3C(=O)C2=C(NCCNCCO)C=C1
ABCG2	DB00541	ATP-binding cassette, sub-family G (WHITE), member 2	approved; investigational	Vincristine	CC[C@]1(O)C[C@H]2CN(C1)CCC1=C(NC3=CC=CC=C13)[C@@](C2)(C(=O)OC)C1=C(OC)C=C2N(C=O)[C@@H]3[C@]4(CCN5CC=C[C@](CC)([C@@H]45)[C@@H](OC(C)=O)[C@]3(O)C(=O)OC)C2=C1
ABCG2	DB00313	ATP-binding cassette, sub-family G (WHITE), member 2	approved; investigational	Valproic Acid	CCCC(CCC)C(O)=O
ABCG2	DB00544	ATP-binding cassette, sub-family G (WHITE), member 2	approved	Fluorouracil	FC1=CNC(=O)NC1=O
ABCG2	DB00495	ATP-binding cassette, sub-family G (WHITE), member 2	approved	Zidovudine	CC1=CN([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2)C(=O)NC1=O
ABCG2	DB01095	ATP-binding cassette, sub-family G (WHITE), member 2	approved	Fluvastatin	CC(C)N1C(\C=C\[C@H](O)C[C@H](O)CC(O)=O)=C(C2=CC=C(F)C=C2)C2=CC=CC=C12
ABCG2	DB00641	ATP-binding cassette, sub-family G (WHITE), member 2	approved	Simvastatin	CCC(C)(C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CCC3C[C@@H](O)CC(=O)O3)[C@@H]12
ABCG2	DB00958	ATP-binding cassette, sub-family G (WHITE), member 2	approved	Carboplatin	N.N.O=C1O[Pt]OC(=O)C11CCC1
ABCG2	DB01076	ATP-binding cassette, sub-family G (WHITE), member 2	approved	Atorvastatin	CC(C)C1=C(C(=O)NC2=CC=CC=C2)C(=C(N1CC[C@@H](O)C[C@@H](O)CC(O)=O)C1=CC=C(F)C=C1)C1=CC=CC=C1
ABCG2	DB01098	ATP-binding cassette, sub-family G (WHITE), member 2	approved	Rosuvastatin	CC(C)C1=NC(=NC(C2=CC=C(F)C=C2)=C1\C=C\[C@H](O)C[C@@H](O)CC(O)=O)N(C)S(=O)(=O)C
ABCG2	DB00441	ATP-binding cassette, sub-family G (WHITE), member 2	approved	Gemcitabine	NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](CO)[C@@H](O)C1(F)F
ABCG2	DB00563	ATP-binding cassette, sub-family G (WHITE), member 2	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
ABCG2	DB01196	ATP-binding cassette, sub-family G (WHITE), member 2	approved	Estramustine	CC12CCC3C(CCC4=C3C=CC(OC(=O)N(CCCl)CCCl)=C4)C1CCC2O
ABCG2	DB00361	ATP-binding cassette, sub-family G (WHITE), member 2	approved; investigational	Vinorelbine	CCC1=CC2CN(C1)CC1=C(NC3=CC=CC=C13)[C@@](C2)(C(=O)OC)C1=C(OC)C=C2N(C)[C@@H]3[C@]4(CCN5CC=C[C@](CC)([C@@H]45)[C@@H](OC(C)=O)[C@]3(O)C(=O)OC)C2=C1
ABCG2	DB00619	ATP-binding cassette, sub-family G (WHITE), member 2	approved	Imatinib	CN1CCN(CC2=CC=C(C=C2)C(=O)NC2=CC(NC3=NC=CC(=N3)C3=CN=CC=C3)=C(C)C=C2)CC1
ABCG2	DB00158	ATP-binding cassette, sub-family G (WHITE), member 2	approved; nutraceutical	Folic Acid	NC1=NC(=O)C2=NC(CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)=CN=C2N1
ABCG2	DB00650	ATP-binding cassette, sub-family G (WHITE), member 2	approved	Leucovorin	NC1=NC(=O)C2=C(NCC(CNC3=CC=C(C=C3)C(=O)N[C@H](CCC(O)=O)C(O)=O)N2C=O)N1
ABCG2	DB00317	ATP-binding cassette, sub-family G (WHITE), member 2	approved; investigational	Gefitinib	COC1=C(OCCCN2CCOCC2)C=C2C(NC3=CC(Cl)=C(F)C=C3)=NC=NC2=C1
ABCG2	DB00530	ATP-binding cassette, sub-family G (WHITE), member 2	approved; investigational	Erlotinib	COCCOC1=C(OCCOC)C=C2C(NC3=CC=CC(=C3)C#C)=NC=NC2=C1
ABCG2	DB00795	ATP-binding cassette, sub-family G (WHITE), member 2	approved	Sulfasalazine	OC(=O)C1=CC(=CC=C1O)\N=N\C1=CC=C(C=C1)S(=O)(=O)NC1=NC=CC=C1
ABCG2	DB00515	ATP-binding cassette, sub-family G (WHITE), member 2	approved	Cisplatin	N[Pt](N)(Cl)Cl
ABCG2	DB01030	ATP-binding cassette, sub-family G (WHITE), member 2	approved; investigational	Topotecan	CC[C@@]1(O)C(=O)OCC2=C1C=C1N(CC3=CC4=C(C=CC(O)=C4CN(C)C)N=C13)C2=O
ABCG2	DB00175	ATP-binding cassette, sub-family G (WHITE), member 2	approved	Pravastatin	CC[C@H](C)C(=O)O[C@H]1C[C@H](O)C=C2C=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC(O)=O)[C@@H]12
ABCG2	DB00531	ATP-binding cassette, sub-family G (WHITE), member 2	approved; investigational	Cyclophosphamide	ClCCN(CCCl)P1(=O)NCCCO1
ABCG2	DB01229	ATP-binding cassette, sub-family G (WHITE), member 2	approved	Paclitaxel	CC(=O)O[C@@H]1C2=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)C3=CC=CC=C3)[C@@H]3[C@@]4(CO[C@@H]4C[C@H](O)[C@@]3(C)C1=O)OC(C)=O)C2(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)C1=CC=CC=C1)C1=CC=CC=C1
ABCG2	DB00877	ATP-binding cassette, sub-family G (WHITE), member 2	approved; investigational	Sirolimus	CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1O
ABCG2	DB00864	ATP-binding cassette, sub-family G (WHITE), member 2	approved; investigational	Tacrolimus	CO[C@@H]1C[C@@H](CC[C@H]1O)\C=C(/C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H]([C@H](C[C@H]2C)OC)[C@H](C[C@@H](C)C\C(C)=C\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]1C)OC
ABCG2	DB00564	ATP-binding cassette, sub-family G (WHITE), member 2	approved; investigational	Carbamazepine	NC(=O)N1C2=CC=CC=C2C=CC2=CC=CC=C12
ABCG2	DB00762	ATP-binding cassette, sub-family G (WHITE), member 2	approved; investigational	Irinotecan	CCC1=C2CN3C(=CC4=C(COC(=O)[C@]4(O)CC)C3=O)C2=NC2=C1C=C(OC(=O)N1CCC(CC1)N1CCCCC1)C=C2
ABCG2	DB01248	ATP-binding cassette, sub-family G (WHITE), member 2	approved; investigational	Docetaxel	CC(=O)O[C@@]12CO[C@@H]1C[C@H](O)[C@]1(C)[C@@H]2[C@H](OC(=O)C2=CC=CC=C2)[C@]2(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C3=CC=CC=C3)C(C)=C([C@@H](O)C1=O)C2(C)C
ABCG2	DB01016	ATP-binding cassette, sub-family G (WHITE), member 2	approved	Glyburide	COC1=C(C=C(Cl)C=C1)C(=O)NCCC1=CC=C(C=C1)S(=O)(=O)NC(=O)NC1CCCCC1
ABCG2	DB00331	ATP-binding cassette, sub-family G (WHITE), member 2	approved	Metformin	CN(C)C(=N)NC(N)=N
ABCG5	DB00973	ATP-binding cassette, sub-family G (WHITE), member 5	approved	Ezetimibe	O[C@@H](CC[C@@H]1[C@H](N(C1=O)C1=CC=C(F)C=C1)C1=CC=C(O)C=C1)C1=CC=C(F)C=C1
ABCG8	DB00973	ATP-binding cassette, sub-family G (WHITE), member 8	approved	Ezetimibe	O[C@@H](CC[C@@H]1[C@H](N(C1=O)C1=CC=C(F)C=C1)C1=CC=C(O)C=C1)C1=CC=C(F)C=C1
ABCG8	DB01076	ATP-binding cassette, sub-family G (WHITE), member 8	approved	Atorvastatin	CC(C)C1=C(C(=O)NC2=CC=CC=C2)C(=C(N1CC[C@@H](O)C[C@@H](O)CC(O)=O)C1=CC=C(F)C=C1)C1=CC=CC=C1
ABCG8	DB01095	ATP-binding cassette, sub-family G (WHITE), member 8	approved	Fluvastatin	CC(C)N1C(\C=C\[C@H](O)C[C@H](O)CC(O)=O)=C(C2=CC=C(F)C=C2)C2=CC=CC=C12
ABCG8	DB00227	ATP-binding cassette, sub-family G (WHITE), member 8	approved; investigational	Lovastatin	CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12
ABCG8	DB00175	ATP-binding cassette, sub-family G (WHITE), member 8	approved	Pravastatin	CC[C@H](C)C(=O)O[C@H]1C[C@H](O)C=C2C=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC(O)=O)[C@@H]12
ABCG8	DB01098	ATP-binding cassette, sub-family G (WHITE), member 8	approved	Rosuvastatin	CC(C)C1=NC(=NC(C2=CC=C(F)C=C2)=C1\C=C\[C@H](O)C[C@@H](O)CC(O)=O)N(C)S(=O)(=O)C
ABCG8	DB00641	ATP-binding cassette, sub-family G (WHITE), member 8	approved	Simvastatin	CCC(C)(C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CCC3C[C@@H](O)CC(=O)O3)[C@@H]12
ACAA1	DB02713	acetyl-CoA acyltransferase 1	experimental	Acetylamino-Acetic Acid	CC(=O)NCC(O)=O
ACAA1	DB03085	acetyl-CoA acyltransferase 1	experimental	Hydroxyacetic Acid	OCC(O)=O
ACAA1	DB03147	acetyl-CoA acyltransferase 1	experimental	Flavin-Adenine Dinucleotide	CC1=CC2=C(C=C1C)N(C[C@H](O)[C@H](O)[C@H](O)CO[P@](O)(=O)O[P@@](O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC3=C1N=CN=C3N)C1=NC(=O)NC(=O)C1=N2
ACACA	DB00121	acetyl-CoA carboxylase alpha	approved; nutraceutical	Biotin	OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12
ACACA	DB01132	acetyl-CoA carboxylase alpha	approved; investigational	Pioglitazone	CCC1=CN=C(CCOC2=CC=C(CC3SC(=O)NC3=O)C=C2)C=C1
ACACB	DB00121	acetyl-CoA carboxylase beta	approved; nutraceutical	Biotin	OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12
ACACB	DB00173	acetyl-CoA carboxylase beta	approved; nutraceutical	Adenine	NC1=C2NC=NC2=NC=N1
ACACB	DB02859	acetyl-CoA carboxylase beta	experimental	Soraphen A	CO[C@H]1[C@H](O)[C@@H](C)[C@H]2O[C@@]1(O)[C@H](C)C(=O)O[C@@H](CCCC[C@H](OC)[C@H](OC)\C=C\[C@@H]2C)C1=CC=CC=C1
ACACB	DB03781	acetyl-CoA carboxylase beta	experimental	2-[4-(2,4-Dichlorophenoxy)Phenoxy]Propanoic Acid	C[C@@H](OC1=CC=C(OC2=CC=C(Cl)C=C2Cl)C=C1)C(O)=O
ACACB	DB07870	acetyl-CoA carboxylase beta	experimental	(2S)-2-(4-{[3-CHLORO-5-(TRIFLUOROMETHYL)PYRIDIN-2-YL]OXY}PHENOXY)PROPANOIC ACID	C[C@@H](OC1=CC=C(OC2=NC=C(C=C2Cl)C(F)(F)F)C=C1)C(O)=O
ACAD8	DB01675	acyl-CoA dehydrogenase family, member 8	experimental	Methacrylyl-Coenzyme A	CC(=C)C(=O)SCCNC(=O)CCNC(=O)[C@@H](O)C(C)(C)CO[P@](O)(=O)O[P@@](O)(=O)OC[C@@H]1O[C@H]([C@H](O)[C@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N
ACAD8	DB03147	acyl-CoA dehydrogenase family, member 8	experimental	Flavin-Adenine Dinucleotide	CC1=CC2=C(C=C1C)N(C[C@H](O)[C@H](O)[C@H](O)CO[P@](O)(=O)O[P@@](O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC3=C1N=CN=C3N)C1=NC(=O)NC(=O)C1=N2
ACAD8	DB00161	acyl-CoA dehydrogenase family, member 8	approved; nutraceutical	L-Valine	CC(C)[C@H](N)C(O)=O
ACADM	DB02910	acyl-CoA dehydrogenase, C-4 to C-12 straight chain	experimental	Octanoyl-Coenzyme A	CCCCCCCC(=O)SCCNC(=O)CCNC(=O)[C@@H](O)C(C)(C)CO[P@](O)(=O)O[P@@](O)(=O)OC[C@@H]1O[C@H]([C@H](O)[C@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N
ACADM	DB03147	acyl-CoA dehydrogenase, C-4 to C-12 straight chain	experimental	Flavin-Adenine Dinucleotide	CC1=CC2=C(C=C1C)N(C[C@H](O)[C@H](O)[C@H](O)CO[P@](O)(=O)O[P@@](O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC3=C1N=CN=C3N)C1=NC(=O)NC(=O)C1=N2
ACADM	DB03415	acyl-CoA dehydrogenase, C-4 to C-12 straight chain	experimental	3-Thiaoctanoyl-Coenzyme A	CCCCCSCC(=O)SCCNC(=O)CCNC(=O)[C@@H](O)C(C)(C)CO[P@](O)(=O)O[P@@](O)(=O)OC[C@@H]1O[C@H]([C@H](O)[C@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N
ACADS	DB00157	acyl-CoA dehydrogenase, C-2 to C-3 short chain	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
ACADS	DB03059	acyl-CoA dehydrogenase, C-2 to C-3 short chain	experimental	Acetoacetyl-Coenzyme A	CC(=O)CC(=O)SCCNC(=O)CCNC(=O)[C@@H](O)C(C)(C)CO[P@](O)(=O)O[P@@](O)(=O)OC[C@@H]1O[C@H]([C@H](O)[C@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N
ACADS	DB03147	acyl-CoA dehydrogenase, C-2 to C-3 short chain	experimental	Flavin-Adenine Dinucleotide	CC1=CC2=C(C=C1C)N(C[C@H](O)[C@H](O)[C@H](O)CO[P@](O)(=O)O[P@@](O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC3=C1N=CN=C3N)C1=NC(=O)NC(=O)C1=N2
ACADSB	DB00167	acyl-CoA dehydrogenase, short/branched chain	approved; nutraceutical	L-Isoleucine	CC[C@H](C)[C@H](N)C(O)=O
ACADSB	DB00313	acyl-CoA dehydrogenase, short/branched chain	approved; investigational	Valproic Acid	CCCC(CCC)C(O)=O
ACADVL	DB01393	acyl-CoA dehydrogenase, very long chain	approved	Bezafibrate	CC(C)(OC1=CC=C(CCNC(=O)C2=CC=C(Cl)C=C2)C=C1)C(O)=O
ACAN	DB02255	aggrecan	experimental	GM6001	CNC(=O)[C@H](CC1=CNC2=CC=CC=C12)NC(=O)[C@H](CC(C)C)CC(=O)NO
ACAT1	DB00795	acetyl-CoA acetyltransferase 1	approved	Sulfasalazine	OC(=O)C1=CC(=CC=C1O)\N=N\C1=CC=C(C=C1)S(=O)(=O)NC1=NC=CC=C1
ACAT2	DB01915	acetyl-CoA acetyltransferase 2	experimental	S-Hydroxycysteine	N[C@@H](CSO)C(O)=O
ACAT2	DB01992	acetyl-CoA acetyltransferase 2	experimental	Coenzyme A	CC(C)(CO[P@](O)(=O)O[P@@](O)(=O)OC[C@@H]1O[C@H]([C@H](O)[C@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N)[C@@H](O)C(=O)NCCC(=O)NCCS
ACAT2	DB00363	acetyl-CoA acetyltransferase 2	approved	Clozapine	CN1CCN(CC1)C1=NC2=CC(Cl)=CC=C2NC2=CC=CC=C12
ACHE	DB00122	acetylcholinesterase	approved; nutraceutical	Choline	C[N+](C)(C)CCO
ACHE	DB00382	acetylcholinesterase	approved	Tacrine	NC1=C2CCCCC2=NC2=CC=CC=C12
ACHE	DB00483	acetylcholinesterase	approved	Gallamine Triethiodide	[I-].[I-].[I-].CC[N+](CC)(CC)CCOC1=CC=CC(OCC[N+](CC)(CC)CC)=C1OCC[N+](CC)(CC)CC
ACHE	DB00545	acetylcholinesterase	approved	Pyridostigmine	CN(C)C(=O)OC1=C[N+](C)=CC=C1
ACHE	DB00674	acetylcholinesterase	approved	Galantamine	COC1=C2O[C@H]3C[C@@H](O)C=C[C@]33CCN(C)CC(C=C1)=C23
ACHE	DB00677	acetylcholinesterase	approved	Isoflurophate	CC(C)OP(F)(=O)OC(C)C
ACHE	DB00733	acetylcholinesterase	approved	Pralidoxime	CN1C=CC=C\C1=C/[NH+]=O
ACHE	DB00805	acetylcholinesterase	approved	Minaprine	CC1=CC(=NN=C1NCCN1CCOCC1)C1=CC=CC=C1
ACHE	DB00843	acetylcholinesterase	approved	Donepezil	COC1=C(OC)C=C2C(=O)C(CC3CCN(CC4=CC=CC=C4)CC3)CC2=C1
ACHE	DB00944	acetylcholinesterase	approved	Demecarium	CN(CCCCCCCCCCN(C)C(=O)OC1=CC=CC(=C1)[N+](C)(C)C)C(=O)OC1=CC=CC(=C1)[N+](C)(C)C
ACHE	DB00981	acetylcholinesterase	approved	Physostigmine	CNC(=O)OC1=CC2=C(C=C1)N(C)[C@H]1N(C)CC[C@@]21C
ACHE	DB00989	acetylcholinesterase	approved; investigational	Rivastigmine	CCN(C)C(=O)OC1=CC=CC(=C1)[C@H](C)N(C)C
ACHE	DB01010	acetylcholinesterase	approved	Edrophonium	CC[N+](C)(C)C1=CC(O)=CC=C1
ACHE	DB01122	acetylcholinesterase	approved	Ambenonium	CC[N+](CC)(CCNC(=O)C(=O)NCC[N+](CC)(CC)CC1=CC=CC=C1Cl)CC1=CC=CC=C1Cl
ACHE	DB01199	acetylcholinesterase	approved	Tubocurarine	COC1=C(O)C2=C3[C@@H](CC4=CC(OC5=C(OC)C=C6CCN(C)[C@@H](CC7=CC=C(O2)C=C7)C6=C5)=C(O)C=C4)[N+](C)(C)CCC3=C1
ACHE	DB01245	acetylcholinesterase	approved	Decamethonium	C[N+](C)(C)CCCCCCCCCC[N+](C)(C)C
ACHE	DB01364	acetylcholinesterase	approved	Ephedrine	CN[C@@H](C)[C@H](O)C1=CC=CC=C1
ACHE	DB01400	acetylcholinesterase	approved	Neostigmine	CN(C)C(=O)OC1=CC(=CC=C1)[N+](C)(C)C
ACHE	DB01805	acetylcholinesterase	experimental	Monoisopropylphosphorylserine	CC(C)O[P@](O)(=O)OC[C@@H](N)C(O)=O
ACHE	DB01928	acetylcholinesterase	experimental	Huperaine A	C\C=C1/[C@@H]2CC3=C(C=CC(=O)N3)[C@@]1(N)CC(C)=C2
ACHE	DB02166	acetylcholinesterase	experimental	Propidium	CC[N+](C)(CC)CCC[N+]1=C(C2=CC=CC=C2)C2=C(C=CC(N)=C2)C2=C1C=C(N)C=C2
ACHE	DB02226	acetylcholinesterase	experimental	3,8-Diamino-6-Phenyl-5-[6-[1-[2-[(1,2,3,4-Tetrahydro-9-Acridinyl)Amino]Ethyl]-1h-1,2,3-Triazol-4-Yl]Hexyl]-Phenanthridinium	NC1=CC2=C(C=C1)C1=CC=C(N)C=C1C(C1=CC=CC=C1)=[N+]2CCCCCCC1=CN(CCNC2=C3CCCCC3=NC3=C2C=CC=C3)N=N1
ACHE	DB02343	acetylcholinesterase	experimental	3,6,9,12,15-Pentaoxaheptadecane	CCOCCOCCOCCOCCOCC
ACHE	DB02404	acetylcholinesterase	experimental	1-Deoxy-1-Thio-Heptaethylene Glycol	OCCOCCOCCOCCOCCOCCOCCS
ACHE	DB02673	acetylcholinesterase	experimental	(4ar,6s,8ar)-11-[8-(1,3-Dioxo-1,3-Dihydro-2h-Isoindol-2-Yl)Octyl]-6-Hydroxy-3-Methoxy-5,6,9,10-Tetrahydro-4ah-[1]Benzofuro[3a,3,2-Ef][2]Benzazepin-11-Ium	COC1=CC=C2C=[N+](CCCCCCCCN3C(=O)C4=CC=CC=C4C3=O)CC[C@]34C=C[C@@H](O)C[C@H]3OC1=C24
ACHE	DB02825	acetylcholinesterase	experimental	Methylphosphonic Acid Ester Group	CP([O-])=O
ACHE	DB02845	acetylcholinesterase	experimental	Methylphosphinic Acid	CP(O)=O
ACHE	DB03005	acetylcholinesterase	experimental	3,8-Diamino-6-Phenyl-5-[6-[1-[2-[(1,2,3,4-Tetrahydro-9-Acridinyl)Amino]Ethyl]-1h-1,2,3-Triazol-5-Yl]Hexyl]-Phenanthridinium	NC1=CC2=C(C=C1)C1=CC=C(N)C=C1C(C1=CC=CC=C1)=[N+]2CCCCCCC1=CN=NN1CCNC1=C2CCCCC2=NC2=C1C=CC=C2
ACHE	DB03128	acetylcholinesterase	experimental	Acetylcholine	CC(=O)OCC[N+](C)(C)C
ACHE	DB03283	acetylcholinesterase	experimental	beta-L-fucose	C[C@@H]1O[C@H](O)[C@@H](O)[C@H](O)[C@@H]1O
ACHE	DB03359	acetylcholinesterase	experimental	M-(N,N,N-Trimethylammonio)-2,2,2-Trifluoro-1,1-Dihydroxyethylbenzene	C[N+](C)(C)C1=CC=CC(=C1)C(O)(O)C(F)(F)F
ACHE	DB03740	acetylcholinesterase	experimental	2-(Acetylamino)-2-Deoxy-a-D-Glucopyranose	CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@H](O)[C@@H]1O
ACHE	DB03814	acetylcholinesterase	experimental	2-(N-Morpholino)-Ethanesulfonic Acid	[O-]S(=O)(=O)CC[NH+]1CCOCC1
ACHE	DB04021	acetylcholinesterase	experimental	MF268	C[C@H]1CN(CCCCCCCCNC=O)C[C@@H](C)O1
ACHE	DB04114	acetylcholinesterase	experimental	3-Chloro-9-Ethyl-6,7,8,9,10,11-Hexahydro-7,11-Methanocycloocta[B]Quinolin-12-Amine	CCC1=C[C@H]2C[C@@H](C1)C1=C(C2)N=C2C=C(Cl)C=CC2=C1N
ACHE	DB04556	acetylcholinesterase	experimental	3-[(1s)-1-(Dimethylamino)Ethyl]Phenol	C[C@H](N(C)C)C1=CC(O)=CC=C1
ACHE	DB04614	acetylcholinesterase	experimental	(R)-tacrine(10)-hupyridone	O=C1NC2=C(C=C1)[C@@H](CCC2)NCCCCCCCCCCNC1=C2CCCCC2=NC2=CC=CC=C12
ACHE	DB04615	acetylcholinesterase	experimental	(S)-tacrine(10)-hupyridone	O=C1NC2=C(C=C1)[C@H](CCC2)NCCCCCCCCCCNC1=C2CCCCC2=NC2=CC=CC=C12
ACHE	DB04616	acetylcholinesterase	experimental	TACRINE(8)-4-AMINOQUINOLINE	C(CCCCNC1=C2CCCCC2=NC2=CC=CC=C12)CCCNC1=CC=NC2=CC=CC=C12
ACHE	DB04617	acetylcholinesterase	experimental	(9S)-9-[(8-AMMONIOOCTYL)AMINO]-1,2,3,4,9,10-HEXAHYDROACRIDINIUM	[NH3+]CCCCCCCCNC1=C2CCCCC2=[NH+]C2=CC=CC=C12
ACHE	DB07555	acetylcholinesterase	experimental	1-(2-nitrophenyl)-2,2,2-trifluoroethyl]-arsenocholine	C[As+](C)(C)CCO[C@@H](C1=CC=CC=C1[N+](O)=O)C(F)(F)F
ACHE	DB07701	acetylcholinesterase	experimental	1-BENZYL-4-[(5,6-DIMETHOXY-1-INDANON-2-YL)METHYL]PIPERIDINE	COC1=C(OC)C=C2C(=O)[C@H](CC3CCN(CC4=CC=CC=C4)CC3)CC2=C1
ACHE	DB07756	acetylcholinesterase	experimental	1-[3-({[(4-AMINO-5-FLUORO-2-METHYLQUINOLIN-3-YL)METHYL]THIO}METHYL)PHENYL]-2,2,2-TRIFLUOROETHANE-1,1-DIOL	CC1=C(CSCC2=CC(=CC=C2)C(O)(O)C(F)(F)F)C(N)=C2C(F)=CC=CC2=N1
ACHE	DB07822	acetylcholinesterase	experimental	(1R)-1,2,2-TRIMETHYLPROPYL (S)-METHYLPHOSPHINATE	C[C@@H](OP(C)=O)C(C)(C)C
ACHE	DB07846	acetylcholinesterase	experimental	1S,3AS,8AS-TRIMETHYL-1-OXIDO-1,2,3,3A,8,8A-HEXAHYDROPYRROLO[2,3-B]INDOL-5-YL 2-ETHYLPHENYLCARBAMATE	CCC1=CC=CC=C1NC(=O)OC1=CC=C2N(C)[C@@H]3[C@](C)(CC[N@+]3(C)[O-])C2=C1
ACHE	DB08167	acetylcholinesterase	experimental	3,7-BIS(DIMETHYLAMINO)PHENOTHIAZIN-5-IUM	CN(C)C1=CC2=[S+]C3=CC(=CC=C3N=C2C=C1)N(C)C
ACHE	DB08357	acetylcholinesterase	experimental	1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE	CCOCCOCCOCC
ACHE	DB08615	acetylcholinesterase	experimental	2-[4-(DIMETHYLAMINO)PHENYL]-6-HYDROXY-3-METHYL-1,3-BENZOTHIAZOL-3-IUM	CN(C)C1=CC=C(C=C1)C1=[N+](C)C2=CC=C(O)C=C2S1
ACMSD	DB00160	aminocarboxymuconate semialdehyde decarboxylase	approved; nutraceutical	L-Alanine	C[C@H](N)C(O)=O
ACMSD	DB00150	aminocarboxymuconate semialdehyde decarboxylase	approved; nutraceutical	L-Tryptophan	N[C@@H](CC1=CNC2=CC=CC=C12)C(O)=O
ACOT8	DB00145	acyl-CoA thioesterase 8	approved; nutraceutical	Glycine	NCC(O)=O
ACOX1	DB03147	acyl-CoA oxidase 1, palmitoyl	experimental	Flavin-Adenine Dinucleotide	CC1=CC2=C(C=C1C)N(C[C@H](O)[C@H](O)[C@H](O)CO[P@](O)(=O)O[P@@](O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC3=C1N=CN=C3N)C1=NC(=O)NC(=O)C1=N2
ACOX1	DB07930	acyl-CoA oxidase 1, palmitoyl	experimental	(3R)-3-HYDROXYDODECANOIC ACID	CCCCCCCCC[C@@H](O)CC(O)=O
ACOX1	DB01039	acyl-CoA oxidase 1, palmitoyl	approved	Fenofibrate	CC(C)OC(=O)C(C)(C)OC1=CC=C(C=C1)C(=O)C1=CC=C(Cl)C=C1
ACOX2	DB00145	acyl-CoA oxidase 2, branched chain	approved; nutraceutical	Glycine	NCC(O)=O
ACP1	DB00173	acid phosphatase 1, soluble	approved; nutraceutical	Adenine	NC1=C2NC=NC2=NC=N1
ACP1	DB04214	acid phosphatase 1, soluble	experimental	4-Nitrophenyl Phosphate	OP(O)(=O)OC1=CC=C(C=C1)[N+]([O-])=O
ACP2	DB01033	acid phosphatase 2, lysosomal	approved	Mercaptopurine	S=C1N=CNC2=C1NC=N2
ACP2	DB00563	acid phosphatase 2, lysosomal	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
ACPP	DB02944	acid phosphatase, prostate	experimental	Alpha-D-Mannose	OC[C@@H]1O[C@H](O)[C@@H](O)[C@H](O)[C@H]1O
ACPP	DB03390	acid phosphatase, prostate	experimental	N-Propyl-Tartramic Acid	CCCNC(=O)[C@@H](O)[C@@H](O)C(O)=O
ACPP	DB03577	acid phosphatase, prostate	experimental	Alpha-Benzyl-Aminobenzyl-Phosphonic Acid	OP(O)(=O)[C@@H](NCC1=CC=CC=C1)C1=CC=CC=C1
ACSL1	DB00131	acyl-CoA synthetase long-chain family member 1	approved; nutraceutical	Adenosine monophosphate	NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
ACSL1	DB00171	acyl-CoA synthetase long-chain family member 1	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
ACSL1	DB00367	acyl-CoA synthetase long-chain family member 1	approved; investigational	Levonorgestrel	CC[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@H]34)[C@@H]1CC[C@@]2(O)C#C
ACSL3	DB00159	acyl-CoA synthetase long-chain family member 3	approved; nutraceutical	Icosapent	CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O
ACSL4	DB00159	acyl-CoA synthetase long-chain family member 4	approved; nutraceutical	Icosapent	CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O
ACSL4	DB00197	acyl-CoA synthetase long-chain family member 4	withdrawn	Troglitazone	CC1=C(C)C2=C(CCC(C)(COC3=CC=C(CC4SC(=O)NC4=O)C=C3)O2)C(C)=C1O
ACSL4	DB00412	acyl-CoA synthetase long-chain family member 4	approved; investigational	Rosiglitazone	CN(CCOC1=CC=C(CC2SC(=O)NC2=O)C=C1)C1=CC=CC=N1
ACSM1	DB00131	acyl-CoA synthetase medium-chain family member 1	approved; nutraceutical	Adenosine monophosphate	NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
ACSM1	DB00171	acyl-CoA synthetase medium-chain family member 1	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
ACSS1	DB00131	acyl-CoA synthetase short-chain family member 1	approved; nutraceutical	Adenosine monophosphate	NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
ACSS1	DB00171	acyl-CoA synthetase short-chain family member 1	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
ACSS2	DB00131	acyl-CoA synthetase short-chain family member 2	approved; nutraceutical	Adenosine monophosphate	NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
ACSS2	DB00171	acyl-CoA synthetase short-chain family member 2	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
ACTB	DB00394	actin, beta	approved	Beclomethasone	C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
ACTB	DB00443	actin, beta	approved	Betamethasone	C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
ACTB	DB01222	actin, beta	approved; investigational	Budesonide	CCC[C@H]1O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO
ACTB	DB01410	actin, beta	approved; investigational	Ciclesonide	CC(C)C(=O)OCC(=O)[C@@]12OC(O[C@@H]1C[C@H]1[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@]21C)C1CCCCC1
ACTB	DB01260	actin, beta	approved; investigational	Desonide	CC1(C)O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO
ACTB	DB01234	actin, beta	approved; investigational	Dexamethasone	C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
ACTB	DB00180	actin, beta	approved; investigational	Flunisolide	CC1(C)O[C@@H]2C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO
ACTB	DB00588	actin, beta	approved; investigational	Fluticasone Propionate	CCC(=O)O[C@@]1([C@H](C)C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)C(=O)SCF
ACTB	DB00741	actin, beta	approved	Hydrocortisone	C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
ACTB	DB00959	actin, beta	approved	Methylprednisolone	C[C@H]1C[C@H]2[C@@H]3CC[C@](O)(C(=O)CO)[C@@]3(C)C[C@H](O)[C@@H]2[C@@]2(C)C=CC(=O)C=C12
ACTB	DB00764	actin, beta	approved	Mometasone	C[C@@H]1C[C@H]2C3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CCl
ACTB	DB01384	actin, beta	approved	Paramethasone	C[C@@H]1C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
ACTB	DB00860	actin, beta	approved	Prednisolone	C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
ACTB	DB00635	actin, beta	approved	Prednisone	C[C@]12CC(=O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
ACTB	DB00896	actin, beta	approved	Rimexolone	CCC(=O)[C@@]1(C)[C@H](C)CC2C3CCC4=CC(=O)C=C[C@]4(C)C3[C@@H](O)C[C@]12C
ACTB	DB00620	actin, beta	approved	Triamcinolone	C[C@]12C[C@H](O)[C@@]3(F)[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1C[C@@H](O)[C@]2(O)C(=O)CO
ACY1	DB00128	aminoacylase 1	approved; nutraceutical	L-Aspartic Acid	N[C@@H](CC(O)=O)C(O)=O
ACY3	DB00128	aspartoacylase (aminocyclase) 3	approved; nutraceutical	L-Aspartic Acid	N[C@@H](CC(O)=O)C(O)=O
ADA	DB00552	adenosine deaminase	approved; investigational	Pentostatin	OC[C@H]1O[C@H](C[C@@H]1O)N1C=NC2=C1N=CNC[C@H]2O
ADA	DB00975	adenosine deaminase	approved	Dipyridamole	OCCN(CCO)C1=NC2=C(N=C(N=C2N2CCCCC2)N(CCO)CCO)C(=N1)N1CCCCC1
ADA	DB02096	adenosine deaminase	experimental	FR221647	NC(=O)C1=CN(C=N1)[C@@H](CO)CCC1=CC=CC=C1
ADA	DB02472	adenosine deaminase	experimental	6-Hydroxy-7,8-Dihydro Purine Nucleoside	OC[C@@H]1O[C@H]([C@H](O)[C@H]1O)N1CNC2=C(O)N=CN=C12
ADA	DB02616	adenosine deaminase	experimental	FR117016	NC(N)=NC1=NC(=CS1)C1=CC=C(CNC2=NC3=C(N2)C=CC=C3)S1
ADA	DB02830	adenosine deaminase	experimental	FR236913	NC(=O)C1=CN(C=N1)[C@@H](CO)CCN1C=CC2=C1C=C(NC(=O)NCC1=CC=CC=C1)C=C2
ADA	DB03015	adenosine deaminase	experimental	6-Hydroxy-1,6-Dihydro Purine Nucleoside	OC[C@@H]1O[C@H]([C@H](O)[C@H]1O)N1C=[NH+]C2=C1N=CN[C@@H]2O
ADA	DB03220	adenosine deaminase	experimental	FR233623	C[C@H](O)[C@@H](CCC1=CC=CC2=C1C=CC=C2)N1C=NC(=C1)C(N)=O
ADA	DB03370	adenosine deaminase	experimental	FR239087	C[C@H](O)[C@@H](CCC1=CC=CC(Cl)=C1Cl)N1C=NC(=C1)C(N)=O
ADA	DB03572	adenosine deaminase	experimental	FR230513	NC(=O)C1=CN(C=N1)[C@@H](CO)CCC1=CC=CC2=C1C=CC=C2
ADA	DB04218	adenosine deaminase	experimental	1-Deaza-Adenosine	NC1=CC=NC2=C1N=CN2[C@@H]1O[C@@H](CO)[C@H](O)[C@H]1O
ADA	DB04440	adenosine deaminase	experimental	Purine Riboside	OC[C@@H]1O[C@H]([C@H](O)[C@H]1O)N1C=[NH+]C2=C1N=CN=C2
ADA	DB07711	adenosine deaminase	experimental	(2S,3R)-3-(6-amino-9H-purin-9-yl)nonan-2-ol	CCCCCC[C@H]([C@H](C)O)N1C=NC2=C(N)N=CN=C12
ADA	DB07783	adenosine deaminase	experimental	1-((1R)-1-(HYDROXYMETHYL)-3-{6-[(3-PHENYLPROPANOYL)AMINO]-1H-INDOL-1-YL}PROPYL)-1H-IMIDAZOLE-4-CARBOXAMIDE	NC(=O)C1=CN(C=N1)[C@@H](CO)CCN1C=CC2=C1C=C(NC(=O)CCC1=CC=CC=C1)C=C2
ADA	DB07785	adenosine deaminase	experimental	1-{(1R,2S)-2-HYDROXY-1-[2-(2-NAPHTHYLOXY)ETHYL]PROPYL}-1H-IMIDAZONE-4-CARBOXAMIDE	C[C@H](O)[C@@H](CCOC1=CC2=C(C=CC=C2)C=C1)N1C=NC(=C1)C(N)=O
ADA	DB07786	adenosine deaminase	experimental	1-((1R,2S)-1-{2-[2-(4-CHLOROPHENYL)-1,3-BENZOXAZOL-7-YL]ETHYL}-2-HYDROXYPROPYL)-1H-IMIDAZOLE-4-CARBOXAMIDE	C[C@H](O)[C@H](CCC1=CC=CC2=C1OC(=N2)C1=CC=C(Cl)C=C1)N1C=NC(=C1)C(N)=O
ADA	DB00173	adenosine deaminase	approved; nutraceutical	Adenine	NC1=C2NC=NC2=NC=N1
ADA	DB00563	adenosine deaminase	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
ADA	DB00640	adenosine deaminase	approved; investigational	Adenosine	NC1=C2N=CN([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)C2=NC=N1
ADC	DB00114	arginine decarboxylase	nutraceutical	Pyridoxal Phosphate	CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O
ADC	DB00125	arginine decarboxylase	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
ADCY1	DB00131	adenylate cyclase 1 (brain)	approved; nutraceutical	Adenosine monophosphate	NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
ADCY1	DB00171	adenylate cyclase 1 (brain)	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
ADCY1	DB00988	adenylate cyclase 1 (brain)	approved	Dopamine	NCCC1=CC(O)=C(O)C=C1
ADCY1	DB00125	adenylate cyclase 1 (brain)	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
ADCY1	DB00155	adenylate cyclase 1 (brain)	approved; nutraceutical	L-Citrulline	N[C@@H](CCCNC(N)=O)C(O)=O
ADCY1	DB00435	adenylate cyclase 1 (brain)	approved	Nitric Oxide	[N]=O
ADCY1	DB00396	adenylate cyclase 1 (brain)	approved	Progesterone	CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C
ADCY1	DB00938	adenylate cyclase 1 (brain)	approved	Salmeterol	OCC1=C(O)C=CC(=C1)C(O)CNCCCCCCOCCCCC1=CC=CC=C1
ADCY2	DB02587	adenylate cyclase 2 (brain)	experimental	Forskolin	CC(=O)O[C@H]1[C@@H](O)[C@H]2C(C)(C)CC[C@H](O)[C@]2(C)[C@@]2(O)C(=O)C[C@@](C)(O[C@]12C)C=C
ADCY2	DB06843	adenylate cyclase 2 (brain)	experimental	2',5'-DIDEOXY-ADENOSINE 3'-MONOPHOSPHATE	C[C@H]1O[C@H](C[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N
ADCY2	DB00938	adenylate cyclase 2 (brain)	approved	Salmeterol	OCC1=C(O)C=CC(=C1)C(O)CNCCCCCCOCCCCC1=CC=CC=C1
ADCY3	DB00938	adenylate cyclase 3	approved	Salmeterol	OCC1=C(O)C=CC(=C1)C(O)CNCCCCCCOCCCCC1=CC=CC=C1
ADCY4	DB00938	adenylate cyclase 4	approved	Salmeterol	OCC1=C(O)C=CC(=C1)C(O)CNCCCCCCOCCCCC1=CC=CC=C1
ADCY5	DB02587	adenylate cyclase 5	experimental	Forskolin	CC(=O)O[C@H]1[C@@H](O)[C@H]2C(C)(C)CC[C@H](O)[C@]2(C)[C@@]2(O)C(=O)C[C@@](C)(O[C@]12C)C=C
ADCY5	DB06843	adenylate cyclase 5	experimental	2',5'-DIDEOXY-ADENOSINE 3'-MONOPHOSPHATE	C[C@H]1O[C@H](C[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N
ADCY5	DB00938	adenylate cyclase 5	approved	Salmeterol	OCC1=C(O)C=CC(=C1)C(O)CNCCCCCCOCCCCC1=CC=CC=C1
ADCY6	DB00938	adenylate cyclase 6	approved	Salmeterol	OCC1=C(O)C=CC(=C1)C(O)CNCCCCCCOCCCCC1=CC=CC=C1
ADCY7	DB00938	adenylate cyclase 7	approved	Salmeterol	OCC1=C(O)C=CC(=C1)C(O)CNCCCCCCOCCCCC1=CC=CC=C1
ADCY8	DB01033	adenylate cyclase 8 (brain)	approved	Mercaptopurine	S=C1N=CNC2=C1NC=N2
ADCY8	DB00563	adenylate cyclase 8 (brain)	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
ADCY8	DB00938	adenylate cyclase 8 (brain)	approved	Salmeterol	OCC1=C(O)C=CC(=C1)C(O)CNCCCCCCOCCCCC1=CC=CC=C1
ADCY9	DB01064	adenylate cyclase 9	approved	Isoproterenol	CC(C)NCC(O)C1=CC(O)=C(O)C=C1
ADCY9	DB00938	adenylate cyclase 9	approved	Salmeterol	OCC1=C(O)C=CC(=C1)C(O)CNCCCCCCOCCCCC1=CC=CC=C1
ADH1A	DB00157	alcohol dehydrogenase 1A (class I), alpha polypeptide	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
ADH1A	DB00898	alcohol dehydrogenase 1A (class I), alpha polypeptide	approved	Ethanol	CCO
ADH1A	DB01213	alcohol dehydrogenase 1A (class I), alpha polypeptide	approved	Fomepizole	CC1=CNN=C1
ADH1A	DB01907	alcohol dehydrogenase 1A (class I), alpha polypeptide	experimental	Nicotinamide-Adenine-Dinucleotide	NC(=O)C1=CC=C[N+](=C1)[C@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@@H]1O
ADH1A	DB02721	alcohol dehydrogenase 1A (class I), alpha polypeptide	experimental	4-Iodopyrazole	Ic1cnnc1
ADH1A	DB04065	alcohol dehydrogenase 1A (class I), alpha polypeptide	experimental	N-Cyclopentyl-N-Cyclobutylformamide	O=CN(C1CCC1)C1CCCC1
ADH1B	DB00157	alcohol dehydrogenase 1B (class I), beta polypeptide	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
ADH1B	DB00898	alcohol dehydrogenase 1B (class I), beta polypeptide	approved	Ethanol	CCO
ADH1B	DB01213	alcohol dehydrogenase 1B (class I), beta polypeptide	approved	Fomepizole	CC1=CNN=C1
ADH1B	DB01907	alcohol dehydrogenase 1B (class I), beta polypeptide	experimental	Nicotinamide-Adenine-Dinucleotide	NC(=O)C1=CC=C[N+](=C1)[C@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@@H]1O
ADH1B	DB02481	alcohol dehydrogenase 1B (class I), beta polypeptide	experimental	N-Benzylformamide	O=CNCC1=CC=CC=C1
ADH1B	DB02721	alcohol dehydrogenase 1B (class I), beta polypeptide	experimental	4-Iodopyrazole	Ic1cnnc1
ADH1B	DB03461	alcohol dehydrogenase 1B (class I), beta polypeptide	experimental	2'-Monophosphoadenosine 5'-Diphosphoribose	NC(=O)C1=CC=C[N+](=C1)[C@@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@@H]2O[C@H]([C@H](OP(O)(O)=O)[C@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@H]1O
ADH1B	DB03703	alcohol dehydrogenase 1B (class I), beta polypeptide	experimental	Cyclohexanol	OC1CCCCC1
ADH1B	DB04077	alcohol dehydrogenase 1B (class I), beta polypeptide	experimental	Glycerol	OCC(O)CO
ADH1B	DB04105	alcohol dehydrogenase 1B (class I), beta polypeptide	experimental	N-Heptylformamide	CCCCCCCNC=O
ADH1C	DB00157	alcohol dehydrogenase 1C (class I), gamma polypeptide	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
ADH1C	DB00898	alcohol dehydrogenase 1C (class I), gamma polypeptide	approved	Ethanol	CCO
ADH1C	DB01213	alcohol dehydrogenase 1C (class I), gamma polypeptide	approved	Fomepizole	CC1=CNN=C1
ADH1C	DB01711	alcohol dehydrogenase 1C (class I), gamma polypeptide	experimental	2,3,4,5,6-Pentafluorobenzyl Alcohol	OCC1=C(F)C(F)=C(F)C(F)=C1F
ADH1C	DB01907	alcohol dehydrogenase 1C (class I), gamma polypeptide	experimental	Nicotinamide-Adenine-Dinucleotide	NC(=O)C1=CC=C[N+](=C1)[C@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@@H]1O
ADH1C	DB02131	alcohol dehydrogenase 1C (class I), gamma polypeptide	experimental	N-1-Methylheptylformamide	CCCCCC[C@H](C)NC=O
ADH1C	DB02249	alcohol dehydrogenase 1C (class I), gamma polypeptide	experimental	2-Ethoxyethanol	CCOCCO
ADH1C	DB02659	alcohol dehydrogenase 1C (class I), gamma polypeptide	experimental	Cholic Acid	C[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C
ADH1C	DB02721	alcohol dehydrogenase 1C (class I), gamma polypeptide	experimental	4-Iodopyrazole	Ic1cnnc1
ADH1C	DB02757	alcohol dehydrogenase 1C (class I), gamma polypeptide	experimental	Pyrazole	N1C=CC=N1
ADH1C	DB02822	alcohol dehydrogenase 1C (class I), gamma polypeptide	experimental	Para-Bromobenzyl Alcohol	OCC1=CC=C(Br)C=C1
ADH1C	DB02871	alcohol dehydrogenase 1C (class I), gamma polypeptide	experimental	3-Butylthiolane 1-Oxide	CCCC[C@H]1CC[S@@](=O)C1
ADH1C	DB03020	alcohol dehydrogenase 1C (class I), gamma polypeptide	experimental	5-Beta-D-Ribofuranosylnicotinamide Adenine Dinucleotide	NC(=O)C1=C[NH+]=CC(=C1)[C@@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@@H]2O[C@H]([C@H](O)[C@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@H]1O
ADH1C	DB03061	alcohol dehydrogenase 1C (class I), gamma polypeptide	experimental	(R)-N-(1-Methyl-Hexyl)-Formamide	CCCCC[C@H](C)NC=O
ADH1C	DB03226	alcohol dehydrogenase 1C (class I), gamma polypeptide	experimental	Trifluoroethanol	OCC(F)(F)F
ADH1C	DB03559	alcohol dehydrogenase 1C (class I), gamma polypeptide	experimental	Cyclohexylformamide	O=CNC1CCCCC1
ADH1C	DB04071	alcohol dehydrogenase 1C (class I), gamma polypeptide	experimental	Cpad	NC(=O)C1=CC=CC(=[NH+]1)[C@@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@@H]2O[C@H]([C@H](O)[C@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@H]1O
ADH1C	DB04113	alcohol dehydrogenase 1C (class I), gamma polypeptide	experimental	N-Formylpiperidine	O=CN1CCCCC1
ADH1C	DB04312	alcohol dehydrogenase 1C (class I), gamma polypeptide	experimental	2,3-Difluorobenzyl Alcohol	OCC1=CC=CC(F)=C1F
ADH1C	DB04448	alcohol dehydrogenase 1C (class I), gamma polypeptide	experimental	2,4-Difluorobenzyl Alcohol 2,4-Difluoro-1-(Hydroxymethyl)Benzene	OCC1=CC=C(F)C=C1F
ADH4	DB00157	alcohol dehydrogenase 4 (class II), pi polypeptide	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
ADH4	DB01907	alcohol dehydrogenase 4 (class II), pi polypeptide	experimental	Nicotinamide-Adenine-Dinucleotide	NC(=O)C1=CC=C[N+](=C1)[C@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@@H]1O
ADH4	DB03559	alcohol dehydrogenase 4 (class II), pi polypeptide	experimental	Cyclohexylformamide	O=CNC1CCCCC1
ADH4	DB00898	alcohol dehydrogenase 4 (class II), pi polypeptide	approved	Ethanol	CCO
ADH5	DB00157	alcohol dehydrogenase 5 (class III), chi polypeptide	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
ADH5	DB01907	alcohol dehydrogenase 5 (class III), chi polypeptide	experimental	Nicotinamide-Adenine-Dinucleotide	NC(=O)C1=CC=C[N+](=C1)[C@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@@H]1O
ADH5	DB03704	alcohol dehydrogenase 5 (class III), chi polypeptide	experimental	12-Hydroxydodecanoic Acid	OCCCCCCCCCCCC(O)=O
ADH5	DB04153	alcohol dehydrogenase 5 (class III), chi polypeptide	experimental	S-Hydroxymethyl Glutathione	N[C@@H](CCC(=O)N[C@H](CSCO)C(=O)NCC(O)=O)C(O)=O
ADH5	DB01001	alcohol dehydrogenase 5 (class III), chi polypeptide	approved	Salbutamol	CC(C)(C)NCC(O)C1=CC(CO)=C(O)C=C1
ADH5	DB00898	alcohol dehydrogenase 5 (class III), chi polypeptide	approved	Ethanol	CCO
ADH6	DB00898	alcohol dehydrogenase 6 (class V)	approved	Ethanol	CCO
ADH7	DB00157	alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
ADH7	DB01907	alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide	experimental	Nicotinamide-Adenine-Dinucleotide	NC(=O)C1=CC=C[N+](=C1)[C@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@@H]1O
ADH7	DB00898	alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide	approved	Ethanol	CCO
ADK	DB00131	adenosine kinase	approved; nutraceutical	Adenosine monophosphate	NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
ADK	DB00811	adenosine kinase	approved	Ribavirin	NC(=O)C1=NN(C=N1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
ADK	DB07173	adenosine kinase	experimental	7-(5-DEOXY-BETA-D-RIBOFURANOSYL)-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-4-AMINE	C[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=C(I)C2=C(N)N=CN=C12
ADK	DB07280	adenosine kinase	experimental	5-[4-(DIMETHYLAMINO)PHENYL]-6-[(6-MORPHOLIN-4-YLPYRIDIN-3-YL)ETHYNYL]PYRIMIDIN-4-AMINE	CN(C)C1=CC=C(C=C1)C1=C(N=CN=C1N)C#CC1=CC=C(N=C1)N1CCOCC1
ADK	DB00173	adenosine kinase	approved; nutraceutical	Adenine	NC1=C2NC=NC2=NC=N1
ADK	DB00640	adenosine kinase	approved; investigational	Adenosine	NC1=C2N=CN([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)C2=NC=N1
ADRA2A	DB00217	adrenoceptor alpha 2A	approved	Bethanidine	CN\C(NCC1=CC=CC=C1)=N/C
ADRA2A	DB00246	adrenoceptor alpha 2A	approved	Ziprasidone	ClC1=C(CCN2CCN(CC2)C2=NSC3=CC=CC=C23)C=C2CC(=O)NC2=C1
ADRA2A	DB00248	adrenoceptor alpha 2A	approved	Cabergoline	CCNC(=O)N(CCCN(C)C)C(=O)[C@@H]1C[C@H]2[C@@H](CC3=CNC4=CC=CC2=C34)N(CC=C)C1
ADRA2A	DB00268	adrenoceptor alpha 2A	approved; investigational	Ropinirole	CCCN(CCC)CCC1=C2CC(=O)NC2=CC=C1
ADRA2A	DB00320	adrenoceptor alpha 2A	approved	Dihydroergotamine	CN1C[C@@H](C[C@H]2[C@H]1CC1=CNC3=CC=CC2=C13)C(=O)N[C@]1(C)O[C@@]2(O)[C@@H]3CCCN3C(=O)[C@H](CC3=CC=CC=C3)N2C1=O
ADRA2A	DB00321	adrenoceptor alpha 2A	approved	Amitriptyline	CN(C)CCC=C1C2=CC=CC=C2CCC2=CC=CC=C12
ADRA2A	DB00334	adrenoceptor alpha 2A	approved; investigational	Olanzapine	CN1CCN(CC1)C1=C2C=C(C)SC2=NC2=CC=CC=C2N1
ADRA2A	DB00363	adrenoceptor alpha 2A	approved	Clozapine	CN1CCN(CC1)C1=NC2=CC(Cl)=CC=C2NC2=CC=CC=C12
ADRA2A	DB00368	adrenoceptor alpha 2A	approved	Norepinephrine	NC[C@H](O)C1=CC(O)=C(O)C=C1
ADRA2A	DB00370	adrenoceptor alpha 2A	approved	Mirtazapine	CN1CCN2C(C1)C1=CC=CC=C1CC1=C2N=CC=C1
ADRA2A	DB00397	adrenoceptor alpha 2A	approved; withdrawn	Phenylpropanolamine	C[C@@H](N)[C@@H](O)C1=CC=CC=C1
ADRA2A	DB00413	adrenoceptor alpha 2A	approved; investigational	Pramipexole	CCCN[C@@H]1CCC2=C(C1)SC(N)=N2
ADRA2A	DB00449	adrenoceptor alpha 2A	approved	Dipivefrin	CNCC(O)C1=CC(OC(=O)C(C)(C)C)=C(OC(=O)C(C)(C)C)C=C1
ADRA2A	DB00484	adrenoceptor alpha 2A	approved	Brimonidine	BrC1=C(NC2=NCCN2)C=CC2=NC=CN=C12
ADRA2A	DB00543	adrenoceptor alpha 2A	approved	Amoxapine	ClC1=CC2=C(OC3=CC=CC=C3N=C2N2CCNCC2)C=C1
ADRA2A	DB00575	adrenoceptor alpha 2A	approved	Clonidine	ClC1=CC=CC(Cl)=C1NC1=NCCN1
ADRA2A	DB00589	adrenoceptor alpha 2A	approved	Lisuride	CCN(CC)C(=O)N[C@@H]1CN(C)[C@@H]2CC3=CNC4=CC=CC(=C34)C2=C1
ADRA2A	DB00629	adrenoceptor alpha 2A	approved	Guanabenz	NC(N)=NN=CC1=C(Cl)C=CC=C1Cl
ADRA2A	DB00633	adrenoceptor alpha 2A	approved	Dexmedetomidine	CC(C1=CN=CN1)C1=CC=CC(C)=C1C
ADRA2A	DB00656	adrenoceptor alpha 2A	approved; investigational	Trazodone	ClC1=CC=CC(=C1)N1CCN(CCCN2N=C3C=CC=CN3C2=O)CC1
ADRA2A	DB00668	adrenoceptor alpha 2A	approved	Epinephrine	CNC[C@H](O)C1=CC(O)=C(O)C=C1
ADRA2A	DB00692	adrenoceptor alpha 2A	approved	Phentolamine	CC1=CC=C(C=C1)N(CC1=NCCN1)C1=CC(O)=CC=C1
ADRA2A	DB00696	adrenoceptor alpha 2A	approved	Ergotamine	CN1C[C@@H](C=C2[C@H]1CC1=CNC3=CC=CC2=C13)C(=O)N[C@]1(C)O[C@@]2(O)[C@@H]3CCCN3C(=O)[C@H](CC3=CC=CC=C3)N2C1=O
ADRA2A	DB00697	adrenoceptor alpha 2A	approved	Tizanidine	ClC1=C(NC2=NCCN2)C2=NSN=C2C=C1
ADRA2A	DB00714	adrenoceptor alpha 2A	approved; investigational	Apomorphine	CN1CCC2=C3[C@H]1CC1=C(C(O)=C(O)C=C1)C3=CC=C2
ADRA2A	DB00734	adrenoceptor alpha 2A	approved; investigational	Risperidone	CC1=C(CCN2CCC(CC2)C2=NOC3=C2C=CC(F)=C3)C(=O)N2CCCCC2=N1
ADRA2A	DB00751	adrenoceptor alpha 2A	approved; investigational	Epinastine	NC1=NCC2N1C1=CC=CC=C1CC1=CC=CC=C21
ADRA2A	DB00797	adrenoceptor alpha 2A	approved	Tolazoline	C(C1=NCCN1)C1=CC=CC=C1
ADRA2A	DB00800	adrenoceptor alpha 2A	approved	Fenoldopam	OC1=CC=C(C=C1)C1CNCCC2=C(Cl)C(O)=C(O)C=C12
ADRA2A	DB00852	adrenoceptor alpha 2A	approved	Pseudoephedrine	CN[C@@H](C)[C@@H](O)C1=CC=CC=C1
ADRA2A	DB00865	adrenoceptor alpha 2A	illicit; approved	Benzphetamine	CC(CC1=CC=CC=C1)N(C)CC1=CC=CC=C1
ADRA2A	DB00925	adrenoceptor alpha 2A	approved	Phenoxybenzamine	CC(COC1=CC=CC=C1)N(CCCl)CC1=CC=CC=C1
ADRA2A	DB00935	adrenoceptor alpha 2A	approved	Oxymetazoline	CC1=CC(=C(O)C(C)=C1CC1=NCCN1)C(C)(C)C
ADRA2A	DB00964	adrenoceptor alpha 2A	approved	Apraclonidine	NC1=CC(Cl)=C(NC2=NCCN2)C(Cl)=C1
ADRA2A	DB00968	adrenoceptor alpha 2A	approved	Methyldopa	C[C@](N)(CC1=CC(O)=C(O)C=C1)C(O)=O
ADRA2A	DB01018	adrenoceptor alpha 2A	approved; investigational	Guanfacine	NC(=N)NC(=O)CC1=C(Cl)C=CC=C1Cl
ADRA2A	DB01049	adrenoceptor alpha 2A	approved	Ergoloid mesylate	CCC(C)(C)C1N2C(=O)C(NC(=O)C3CC4C(CC5=CNC6=CC=CC4=C56)N(C)C3)(OC2(O)C2CCCN2C1=O)C(C)C
ADRA2A	DB01142	adrenoceptor alpha 2A	approved	Doxepin	CN(C)CC\C=C1/C2=CC=CC=C2COC2=CC=CC=C12
ADRA2A	DB01149	adrenoceptor alpha 2A	approved; withdrawn	Nefazodone	CCC1=NN(CCCN2CCN(CC2)C2=CC(Cl)=CC=C2)C(=O)N1CCOC1=CC=CC=C1
ADRA2A	DB01186	adrenoceptor alpha 2A	approved; withdrawn	Pergolide	CCCN1C[C@H](CSC)C[C@H]2[C@H]1CC1=CNC3=CC=CC2=C13
ADRA2A	DB01200	adrenoceptor alpha 2A	approved; investigational	Bromocriptine	CC(C)C[C@@H]1N2C(=O)[C@](NC(=O)[C@H]3CN(C)[C@@H]4CC5=C(Br)NC6=CC=CC(=C56)C4=C3)(O[C@@]2(O)[C@@H]2CCCN2C1=O)C(C)C
ADRA2A	DB01224	adrenoceptor alpha 2A	approved	Quetiapine	OCCOCCN1CCN(CC1)C1=NC2=CC=CC=C2SC2=CC=CC=C12
ADRA2A	DB01238	adrenoceptor alpha 2A	approved; investigational	Aripiprazole	ClC1=CC=CC(N2CCN(CCCCOC3=CC4=C(CCC(=O)N4)C=C3)CC2)=C1Cl
ADRA2A	DB01267	adrenoceptor alpha 2A	approved	Paliperidone	CC1=C(CCN2CCC(CC2)C2=NOC3=C2C=CC(F)=C3)C(=O)N2CCCC(O)C2=N1
ADRA2A	DB01287	adrenoceptor alpha 2A	approved	Dihydroergotoxine	CS(O)(=O)=O.CN1C[C@@H](CC2[C@H]1CC1=CNC3=CC=CC2=C13)C(=O)N[C@]1(C)O[C@@]2(O)[C@@H]3CCCN3C(=O)[C@H](CC3=CC=CC=C3)N2C1=O
ADRA2A	DB01392	adrenoceptor alpha 2A	approved	Yohimbine	COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCC4=C(NC5=CC=CC=C45)[C@@H]3C[C@H]12
ADRA2A	DB01403	adrenoceptor alpha 2A	approved	Methotrimeprazine	COC1=CC2=C(SC3=C(C=CC=C3)N2C[C@H](C)CN(C)C)C=C1
ADRA2A	DB01472	adrenoceptor alpha 2A	illicit; experimental	4-Methoxyamphetamine	COC1=CC=C(CC(C)N)C=C1
ADRA2A	DB01577	adrenoceptor alpha 2A	illicit; approved	Methamphetamine	CN[C@@H](C)CC1=CC=CC=C1
ADRA2A	DB01608	adrenoceptor alpha 2A	approved	Propericiazine	OC1CCN(CCCN2C3=CC=CC=C3SC3=C2C=C(C=C3)C#N)CC1
ADRA2A	DB01624	adrenoceptor alpha 2A	approved	Zuclopenthixol	OCCN1CCN(CC\C=C2\C3=CC=CC=C3SC3=C2C=C(Cl)C=C3)CC1
ADRA2A	DB04948	adrenoceptor alpha 2A	approved; investigational	Lofexidine	CC(OC1=C(Cl)C=CC=C1Cl)C1=NCCN1
ADRA2A	DB06148	adrenoceptor alpha 2A	approved	Mianserin	CN1CCN2C(C1)C1=CC=CC=C1CC1=CC=CC=C21
ADRA2A	DB06262	adrenoceptor alpha 2A	approved; investigational	Droxidopa	N[C@H]([C@@H](O)C1=CC(O)=C(O)C=C1)C(O)=O
ADRA2A	DB06694	adrenoceptor alpha 2A	approved	Xylometazoline	CC1=CC(=CC(C)=C1CC1=NCCN1)C(C)(C)C
ADRA2A	DB06711	adrenoceptor alpha 2A	approved	Naphazoline	C(C1=NCCN1)C1=CC=CC2=CC=CC=C12
ADRA2A	DB01105	adrenoceptor alpha 2A	illicit; approved; withdrawn; investigational	Sibutramine	CC(C)CC(N(C)C)C1(CCC1)C1=CC=C(Cl)C=C1
ADRA2A	DB00422	adrenoceptor alpha 2A	approved; investigational	Methylphenidate	COC(=O)C(C1CCCCN1)C1=CC=CC=C1
ADSL	DB00145	adenylosuccinate lyase	approved; nutraceutical	Glycine	NCC(O)=O
ADSL	DB00130	adenylosuccinate lyase	approved; nutraceutical; investigational	L-Glutamine	N[C@@H](CCC(N)=O)C(O)=O
ADSS	DB02109	adenylosuccinate synthase	experimental	Hadacidin	ON(CC(O)=O)C=O
ADSS	DB02493	adenylosuccinate synthase	experimental	Hydantocidin-5'-Phosphate	O[C@@H]1[C@@H](COP(O)(O)=O)O[C@@]2(NC(=O)NC2=O)[C@H]1O
ADSS	DB02666	adenylosuccinate synthase	experimental	(C8-R)-Hydantocidin 5'-Phosphate	OCN(O)[C@@H](CCCN1C(=O)N[C@]2(O[C@@H](COP(O)(O)=O)[C@H](O)[C@H]2O)C1=O)C(O)=O
ADSS	DB02682	adenylosuccinate synthase	experimental	2-Deamino-6-Deoxy-6thiophosphite-5'-Phosphate Guanosine	O[C@@H]1[C@@H](COP(O)(O)=O)O[C@@H]([C@H]1O)N1C=NC2=C1N=C[NH+]=C2SP(O)(O)=O
ADSS	DB02836	adenylosuccinate synthase	experimental	Guanosine 5'-Diphosphate 2':3'-Cyclic Monophosphate	NC1=NC2=C(N=CN2[C@H]2O[C@H](CO[P@](O)(=O)OP(O)(O)=O)[C@@H]3O[P@](O)(=O)O[C@H]23)C(=O)N1
ADSS	DB02954	adenylosuccinate synthase	experimental	(Carboxyhydroxyamino)Ethanoic Acid	ON(CC(O)=O)C(O)=O
ADSS	DB03146	adenylosuccinate synthase	experimental	2-Deazo-6-Thiophosphate Guanosine-5'-Monophosphate	O[C@@H]1[C@@H](COP(O)(O)=O)O[C@@H]([C@H]1O)N1C=NC2=C1N=C[NH+]=C2SP(O)(O)=O
ADSS	DB04315	adenylosuccinate synthase	experimental	Guanosine-5'-Diphosphate	NC1=NC2=C(N=CN2[C@@H]2O[C@@H](CO[P@](O)(=O)OP(O)(O)=O)[C@H](O)[C@H]2O)C(=O)N1
ADSS	DB04460	adenylosuccinate synthase	experimental	(C8-S)-Hydantocidin 5'-Phosphate	OCN(O)[C@@H](CCCN1C(=O)N[C@]2(O[C@@H](COP(O)(O)=O)[C@H](O)[C@H]2O)C1=O)C(O)=O
ADSS	DB04566	adenylosuccinate synthase	experimental	Inosinic Acid	O[C@H]1[C@H](COP(O)(O)=O)O[C@H]([C@@H]1O)N1C=NC2=C1N=CNC2=O
ADSS	DB04160	adenylosuccinate synthase	experimental	Diphosphate	[O-]P([O-])(=O)OP([O-])([O-])=O
ADSS	DB00128	adenylosuccinate synthase	approved; nutraceutical	L-Aspartic Acid	N[C@@H](CC(O)=O)C(O)=O
ADSS	DB03510	adenylosuccinate synthase	experimental	6-O-Phosphoryl Inosine Monophosphate	O[C@H]1[C@H](COP(O)(O)=O)O[C@H]([C@@H]1O)N1C=NC2=C1N=CN=C2OP(O)(O)=O
ADSS	DB02580	adenylosuccinate synthase	experimental	1-(2-Methoxy-Ethoxy)-2-{2-[2-(2-Methoxy-Ethoxy]-Ethoxy}-Ethane	COCCOCCOCCOCCOCCOC
ADSS	DB00864	adenylosuccinate synthase	approved; investigational	Tacrolimus	CO[C@@H]1C[C@@H](CC[C@H]1O)\C=C(/C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H]([C@H](C[C@H]2C)OC)[C@H](C[C@@H](C)C\C(C)=C\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]1C)OC
ADSSL1	DB00128	adenylosuccinate synthase like 1	approved; nutraceutical	L-Aspartic Acid	N[C@@H](CC(O)=O)C(O)=O
ADSSL1	DB02109	adenylosuccinate synthase like 1	experimental	Hadacidin	ON(CC(O)=O)C=O
ADSSL1	DB03510	adenylosuccinate synthase like 1	experimental	6-O-Phosphoryl Inosine Monophosphate	O[C@H]1[C@H](COP(O)(O)=O)O[C@H]([C@@H]1O)N1C=NC2=C1N=CN=C2OP(O)(O)=O
ADSSL1	DB04137	adenylosuccinate synthase like 1	experimental	Guanosine-5'-Triphosphate	NC1=NC2=C(N=CN2[C@@H]2O[C@@H](CO[P@](O)(=O)O[P@@](O)(=O)OP(O)(O)=O)[C@H](O)[C@H]2O)C(=O)N1
ADSSL1	DB04315	adenylosuccinate synthase like 1	experimental	Guanosine-5'-Diphosphate	NC1=NC2=C(N=CN2[C@@H]2O[C@@H](CO[P@](O)(=O)OP(O)(O)=O)[C@H](O)[C@H]2O)C(=O)N1
ADSSL1	DB04418	adenylosuccinate synthase like 1	experimental	Adenylosuccinic Acid	O[C@@H]1[C@@H](COP(O)(O)=O)O[C@H]([C@@H]1O)N1C=NC2=C(N[C@@H](CC(O)=O)C(O)=O)N=CN=C12
ADSSL1	DB04566	adenylosuccinate synthase like 1	experimental	Inosinic Acid	O[C@H]1[C@H](COP(O)(O)=O)O[C@H]([C@@H]1O)N1C=NC2=C1N=CNC2=O
AFMID	DB00130	arylformamidase	approved; nutraceutical; investigational	L-Glutamine	N[C@@H](CCC(N)=O)C(O)=O
AFMID	DB00160	arylformamidase	approved; nutraceutical	L-Alanine	C[C@H](N)C(O)=O
AFMID	DB00150	arylformamidase	approved; nutraceutical	L-Tryptophan	N[C@@H](CC1=CNC2=CC=CC=C12)C(O)=O
AGMAT	DB00125	agmatine ureohydrolase (agmatinase)	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
AGMAT	DB03904	agmatine ureohydrolase (agmatinase)	experimental	Urea	NC(N)=O
AGT	DB00999	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	approved	Hydrochlorothiazide	NS(=O)(=O)C1=C(Cl)C=C2NCNS(=O)(=O)C2=C1
AGT	DB00678	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	approved	Losartan	CCCCC1=NC(Cl)=C(CO)N1CC1=CC=C(C=C1)C1=CC=CC=C1C1=NNN=N1
AGT	DB00790	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	approved	Perindopril	CCC[C@H](N[C@@H](C)C(=O)N1[C@H]2CCCC[C@H]2C[C@H]1C(O)=O)C(=O)OCC
AGT	DB01197	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	approved	Captopril	C[C@H](CS)C(=O)N1CCC[C@H]1C(O)=O
AGT	DB00269	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	approved	Chlorotrianisene	COC1=CC=C(C=C1)C(Cl)=C(C1=CC=C(OC)C=C1)C1=CC=C(OC)C=C1
AGT	DB00286	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	approved	Conjugated Estrogens	[Na+].C[C@]12CC[C@H]3[C@@H](CCC4=CC(OS([O-])(=O)=O)=CC=C34)[C@@H]1CCC2=O
AGT	DB00890	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	approved	Dienestrol	CC=C(C(=CC)C1=CC=C(O)C=C1)C1=CC=C(O)C=C1
AGT	DB00255	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	approved	Diethylstilbestrol	CCC(=C(CC)C1=CC=C(O)C=C1)C1=CC=C(O)C=C1
AGT	DB00783	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	approved; investigational	Estradiol	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CC[C@@H]2O
AGT	DB00655	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	approved	Estrone	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CCC2=O
AGT	DB00977	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	approved	Ethinyl Estradiol	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CC[C@@]2(O)C#C
AGT	DB00394	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	approved	Beclomethasone	C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
AGT	DB00443	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	approved	Betamethasone	C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
AGT	DB01222	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	approved; investigational	Budesonide	CCC[C@H]1O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO
AGT	DB01410	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	approved; investigational	Ciclesonide	CC(C)C(=O)OCC(=O)[C@@]12OC(O[C@@H]1C[C@H]1[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@]21C)C1CCCCC1
AGT	DB01260	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	approved; investigational	Desonide	CC1(C)O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO
AGT	DB01234	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	approved; investigational	Dexamethasone	C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
AGT	DB00180	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	approved; investigational	Flunisolide	CC1(C)O[C@@H]2C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO
AGT	DB00588	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	approved; investigational	Fluticasone Propionate	CCC(=O)O[C@@]1([C@H](C)C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)C(=O)SCF
AGT	DB00741	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	approved	Hydrocortisone	C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
AGT	DB00959	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	approved	Methylprednisolone	C[C@H]1C[C@H]2[C@@H]3CC[C@](O)(C(=O)CO)[C@@]3(C)C[C@H](O)[C@@H]2[C@@]2(C)C=CC(=O)C=C12
AGT	DB00764	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	approved	Mometasone	C[C@@H]1C[C@H]2C3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CCl
AGT	DB01384	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	approved	Paramethasone	C[C@@H]1C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
AGT	DB00860	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	approved	Prednisolone	C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
AGT	DB00635	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	approved	Prednisone	C[C@]12CC(=O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
AGT	DB00896	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	approved	Rimexolone	CCC(=O)[C@@]1(C)[C@H](C)CC2C3CCC4=CC(=O)C=C[C@]4(C)C3[C@@H](O)C[C@]12C
AGT	DB00620	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	approved	Triamcinolone	C[C@]12C[C@H](O)[C@@]3(F)[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1C[C@@H](O)[C@]2(O)C(=O)CO
AGT	DB00125	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
AGT	DB00155	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	approved; nutraceutical	L-Citrulline	N[C@@H](CCCNC(N)=O)C(O)=O
AGT	DB00435	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	approved	Nitric Oxide	[N]=O
AGT	DB00131	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	approved; nutraceutical	Adenosine monophosphate	NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
AGT	DB00171	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
AGT	DB00335	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	approved	Atenolol	CC(C)NCC(O)COC1=CC=C(CC(N)=O)C=C1
AGT	DB00722	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	approved; investigational	Lisinopril	NCCCC[C@H](N[C@@H](CCC1=CC=CC=C1)C(O)=O)C(=O)N1CCC[C@H]1C(O)=O
AGT	DB01115	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	approved	Nifedipine	COC(=O)C1=C(C)NC(C)=C(C1C1=CC=CC=C1[N+]([O-])=O)C(=O)OC
AGT	DB01258	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	approved; investigational	Aliskiren	COCCCOC1=C(OC)C=CC(C[C@@H](C[C@H](N)[C@@H](O)C[C@@H](C(C)C)C(=O)NCC(C)(C)C(N)=O)C(C)C)=C1
AGXT	DB00114	alanine-glyoxylate aminotransferase	nutraceutical	Pyridoxal Phosphate	CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O
AGXT	DB00133	alanine-glyoxylate aminotransferase	approved; nutraceutical	L-Serine	N[C@@H](CO)C(O)=O
AGXT	DB00145	alanine-glyoxylate aminotransferase	approved; nutraceutical	Glycine	NCC(O)=O
AGXT	DB00160	alanine-glyoxylate aminotransferase	approved; nutraceutical	L-Alanine	C[C@H](N)C(O)=O
AGXT	DB02079	alanine-glyoxylate aminotransferase	experimental	(Aminooxy)Acetic Acid	NOCC(O)=O
AGXT	DB04083	alanine-glyoxylate aminotransferase	experimental	N'-Pyridoxyl-Lysine-5'-Monophosphate	CC1=NC=C(COP(O)(O)=O)C(CNCCCC[C@@H](N)C(O)=O)=C1O
AGXT	DB08060	alanine-glyoxylate aminotransferase	experimental	4-(2-AMINOPHENYL)-4-OXOBUTANOIC ACID	NC1=CC=CC=C1C(=O)CCC(O)=O
AGXT2	DB00114	alanine--glyoxylate aminotransferase 2	nutraceutical	Pyridoxal Phosphate	CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O
AGXT2	DB00119	alanine--glyoxylate aminotransferase 2	approved; nutraceutical	Pyruvic acid	CC(=O)C(O)=O
AGXT2	DB00145	alanine--glyoxylate aminotransferase 2	approved; nutraceutical	Glycine	NCC(O)=O
AGXT2	DB00160	alanine--glyoxylate aminotransferase 2	approved; nutraceutical	L-Alanine	C[C@H](N)C(O)=O
AHCY	DB01907	adenosylhomocysteinase	experimental	Nicotinamide-Adenine-Dinucleotide	NC(=O)C1=CC=C[N+](=C1)[C@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@@H]1O
AHCY	DB03216	adenosylhomocysteinase	experimental	(1'r,2's)-9-(2-Hydroxy-3'-Keto-Cyclopenten-1-Yl)Adenine	NC1=NC=NC2=C1N=CN2[C@@H]1C=C[C@H](O)[C@H]1O
AHCY	DB03273	adenosylhomocysteinase	experimental	3'-Oxo-Adenosine	NC1=NC=NC2=C1N=CN2[C@H]1O[C@@H](CO)C(=O)[C@@H]1O
AHCY	DB03769	adenosylhomocysteinase	experimental	D-Eritadenine	NC1=NC=NC2=C1N=CN2C[C@H](O)[C@@H](O)C(O)=O
AHCY	DB07052	adenosylhomocysteinase	experimental	5'-S-ethyl-5'-thioadenosine	CCSC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C1N=CN=C2N
AHCY	DB00640	adenosylhomocysteinase	approved; investigational	Adenosine	NC1=C2N=CN([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)C2=NC=N1
AHCY	DB00134	adenosylhomocysteinase	approved; nutraceutical	L-Methionine	CSCC[C@H](N)C(O)=O
AHCY	DB01033	adenosylhomocysteinase	approved	Mercaptopurine	S=C1N=CNC2=C1NC=N2
AHCY	DB00563	adenosylhomocysteinase	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
AK1	DB01717	adenylate kinase 1	experimental	Bis(Adenosine)-5'-Pentaphosphate	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](CO[P@](O)(=O)O[P@@](O)(=O)OP(O)(=O)O[P@](O)(=O)O[P@@](O)(=O)OC[C@@H]2O[C@H]([C@H](O)[C@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@H]1O
AKAP5	DB00864	A kinase (PRKA) anchor protein 5	approved; investigational	Tacrolimus	CO[C@@H]1C[C@@H](CC[C@H]1O)\C=C(/C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H]([C@H](C[C@H]2C)OC)[C@H](C[C@@H](C)C\C(C)=C\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]1C)OC
AKR1A1	DB01907	aldo-keto reductase family 1, member A1 (aldehyde reductase)	experimental	Nicotinamide-Adenine-Dinucleotide	NC(=O)C1=CC=C[N+](=C1)[C@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@@H]1O
AKR1A1	DB02383	aldo-keto reductase family 1, member A1 (aldehyde reductase)	experimental	Tolrestat	COC1=C(C2=CC=CC(C(=S)N(C)CC(O)=O)=C2C=C1)C(F)(F)F
AKR1A1	DB03461	aldo-keto reductase family 1, member A1 (aldehyde reductase)	experimental	2'-Monophosphoadenosine 5'-Diphosphoribose	NC(=O)C1=CC=C[N+](=C1)[C@@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@@H]2O[C@H]([C@H](OP(O)(O)=O)[C@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@H]1O
AKR1A1	DB00997	aldo-keto reductase family 1, member A1 (aldehyde reductase)	approved; investigational	Doxorubicin	COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3O[C@H]3C[C@H](N)[C@H](O)[C@H](C)O3)C(=O)CO)C(O)=C1C2=O
AKR1B1	DB00157	aldo-keto reductase family 1, member B1 (aldose reductase)	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
AKR1B1	DB00605	aldo-keto reductase family 1, member B1 (aldose reductase)	approved	Sulindac	CC1=C(CC(O)=O)C2=C(C=CC(F)=C2)C1=CC1=CC=C(C=C1)S(C)=O
AKR1B1	DB01689	aldo-keto reductase family 1, member B1 (aldose reductase)	experimental	Inhibitor Idd 384	CC1=CC=CC=C1CC(=O)NC1=CC(C)=C(C(C)=C1)S(=O)(=O)NCC(O)=O
AKR1B1	DB02007	aldo-keto reductase family 1, member B1 (aldose reductase)	experimental	Alpha-D-Glucose-6-Phosphate	O[C@H]1O[C@@H](COP(O)(O)=O)[C@H](O)[C@@H](O)[C@@H]1O
AKR1B1	DB02020	aldo-keto reductase family 1, member B1 (aldose reductase)	experimental	Alrestatin	OC(=O)CN1C(=O)C2=CC=CC3=CC=CC(C1=O)=C23
AKR1B1	DB02021	aldo-keto reductase family 1, member B1 (aldose reductase)	experimental	Fidarestat	NC(=O)[C@H]1C[C@]2(NC(=O)NC2=O)C2=CC(F)=CC=C2O1
AKR1B1	DB02101	aldo-keto reductase family 1, member B1 (aldose reductase)	experimental	Fidarestat(Stereoisomer)	NC(=O)[C@H]1C[C@]2(NC(=O)NC2=O)C2=CC(F)=CC=C2O1
AKR1B1	DB02132	aldo-keto reductase family 1, member B1 (aldose reductase)	experimental	[3-(4-Bromo-2-Fluoro-Benzyl)-7-Chloro-2,4-Dioxo-3,4-Dihydro-2h-Quinazolin-1-Yl]-Acetic Acid	OC(=O)CN1C(=O)N(CC2=C(F)C=C(Br)C=C2)C(=O)C2=C1C=C(Cl)C=C2
AKR1B1	DB02383	aldo-keto reductase family 1, member B1 (aldose reductase)	experimental	Tolrestat	COC1=C(C2=CC=CC(C(=S)N(C)CC(O)=O)=C2C=C1)C(F)(F)F
AKR1B1	DB02518	aldo-keto reductase family 1, member B1 (aldose reductase)	experimental	N-Acetylalanine	C[C@@H](NC(C)=O)C(O)=O
AKR1B1	DB02712	aldo-keto reductase family 1, member B1 (aldose reductase)	experimental	Sorbinil	FC1=CC=C2OCC[C@]3(NC(=O)NC3=O)C2=C1
AKR1B1	DB02834	aldo-keto reductase family 1, member B1 (aldose reductase)	experimental	IDD552	OC(=O)COC1=CC(F)=CC=C1C(=O)NCC1=NC2=C(S1)C(F)=CC(F)=C2F
AKR1B1	DB02994	aldo-keto reductase family 1, member B1 (aldose reductase)	experimental	Hydroxydimethylarsine Oxide	C[As](C)(O)=O
AKR1B1	DB03461	aldo-keto reductase family 1, member B1 (aldose reductase)	experimental	2'-Monophosphoadenosine 5'-Diphosphoribose	NC(=O)C1=CC=C[N+](=C1)[C@@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@@H]2O[C@H]([C@H](OP(O)(O)=O)[C@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@H]1O
AKR1B1	DB04272	aldo-keto reductase family 1, member B1 (aldose reductase)	experimental	Citric Acid	OC(=O)CC(O)(CC(O)=O)C(O)=O
AKR1B1	DB07028	aldo-keto reductase family 1, member B1 (aldose reductase)	experimental	(2-{[(4-BROMO-2-FLUOROBENZYL)AMINO]CARBONYL}-5-CHLOROPHENOXY)ACETIC ACID	OC(=O)COC1=CC(Cl)=CC=C1C(=O)NCC1=C(F)C=C(Br)C=C1
AKR1B1	DB07030	aldo-keto reductase family 1, member B1 (aldose reductase)	experimental	(5-CHLORO-2-{[(3-NITROBENZYL)AMINO]CARBONYL}PHENOXY)ACETIC ACID	OC(=O)COC1=CC(Cl)=CC=C1C(=O)NCC1=CC(=CC=C1)[N+]([O-])=O
AKR1B1	DB07063	aldo-keto reductase family 1, member B1 (aldose reductase)	experimental	{3-[(4,5,7-TRIFLUORO-1,3-BENZOTHIAZOL-2-YL)METHYL]-1H-INDOL-1-YL}ACETIC ACID	OC(=O)CN1C=C(CC2=NC3=C(S2)C(F)=CC(F)=C3F)C2=C1C=CC=C2
AKR1B1	DB07093	aldo-keto reductase family 1, member B1 (aldose reductase)	experimental	{3-[(5-CHLORO-1,3-BENZOTHIAZOL-2-YL)METHYL]-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL}ACETIC ACID	OC(=O)CN1C=CC(=O)N(CC2=NC3=CC(Cl)=CC=C3S2)C1=O
AKR1B1	DB07139	aldo-keto reductase family 1, member B1 (aldose reductase)	experimental	3-[5-(3-nitrophenyl)thiophen-2-yl]propanoic acid	OC(=O)CCC1=CC=C(S1)C1=CC(=CC=C1)[N+]([O-])=O
AKR1B1	DB07187	aldo-keto reductase family 1, member B1 (aldose reductase)	experimental	6-[(5-CHLORO-3-METHYL-1-BENZOFURAN-2-YL)SULFONYL]PYRIDAZIN-3(2H)-ONE	CC1=C(OC2=CC=C(Cl)C=C12)S(=O)(=O)C1=NNC(=O)C=C1
AKR1B1	DB07450	aldo-keto reductase family 1, member B1 (aldose reductase)	experimental	2[4-BROMO-2-FLUOROPHENYL)METHYL]-6-FLUOROSPIRO[ISOQUINOLINE-4-(1H),3'-PYRROLIDINE]-1,2',3,5'(2H)-TETRONE	FC1=CC=C2C(=O)N(CC3=CC=C(Br)C=C3F)C(=O)[C@]3(CC(=O)NC3=O)C2=C1
AKR1B1	DB07498	aldo-keto reductase family 1, member B1 (aldose reductase)	experimental	4-[3-(3-NITROPHENYL)-1,2,4-OXADIAZOL-5-YL]BUTANOIC ACID	OC(=O)CCCC1=NC(=NO1)C1=CC(=CC=C1)[N+]([O-])=O
AKR1B1	DB07999	aldo-keto reductase family 1, member B1 (aldose reductase)	experimental	{4-[(CARBOXYMETHOXY)CARBONYL]-3,3-DIOXIDO-1-OXONAPHTHO[1,2-D]ISOTHIAZOL-2(1H)-YL}ACETIC ACID	OC(=O)COC(=O)C1=C2C(C(=O)N(CC(O)=O)S2(=O)=O)=C2C=CC=CC2=C1
AKR1B1	DB08000	aldo-keto reductase family 1, member B1 (aldose reductase)	experimental	2-(CARBOXYMETHYL)-1-OXO-1,2-DIHYDRONAPHTHO[1,2-D]ISOTHIAZOLE-4-CARBOXYLIC ACID 3,3-DIOXIDE	OC(=O)CN1C(=O)C2=C(C(=CC3=CC=CC=C23)C(O)=O)S1(=O)=O
AKR1B1	DB08084	aldo-keto reductase family 1, member B1 (aldose reductase)	experimental	IDD594	OC(=O)COC1=CC(F)=CC=C1C(=S)NCC1=CC=C(Br)C=C1F
AKR1B1	DB08098	aldo-keto reductase family 1, member B1 (aldose reductase)	experimental	{[5-(5-NITRO-2-FURYL)-1,3,4-OXADIAZOL-2-YL]THIO}ACETIC ACID	OC(=O)CSC1=NN=C(O1)C1=CC=C(O1)[N+]([O-])=O
AKR1B1	DB08449	aldo-keto reductase family 1, member B1 (aldose reductase)	experimental	2-(3-((4,5,7-trifluorobenzo[d]thiazol-2-yl)methyl)-1H-pyrrolo[2,3-b]pyridin-1-yl)acetic acid	OC(=O)CN1C=C(CC2=NC3=C(S2)C(F)=CC(F)=C3F)C2=CC=CN=C12
AKR1B1	DB08772	aldo-keto reductase family 1, member B1 (aldose reductase)	experimental	3,4-DIHYDRO-4-OXO-3-((5-TRIFLUOROMETHYL-2-BENZOTHIAZOLYL)METHYL)-1-PHTHALAZINE ACETIC ACID	OC(=O)CC1=NN(CC2=NC3=C(S2)C=CC(=C3)C(F)(F)F)C(=O)C2=C1C=CC=C2
AKR1B10	DB02383	aldo-keto reductase family 1, member B10 (aldose reductase)	experimental	Tolrestat	COC1=C(C2=CC=CC(C(=S)N(C)CC(O)=O)=C2C=C1)C(F)(F)F
AKR1B10	DB03461	aldo-keto reductase family 1, member B10 (aldose reductase)	experimental	2'-Monophosphoadenosine 5'-Diphosphoribose	NC(=O)C1=CC=C[N+](=C1)[C@@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@@H]2O[C@H]([C@H](OP(O)(O)=O)[C@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@H]1O
AKR1B10	DB08772	aldo-keto reductase family 1, member B10 (aldose reductase)	experimental	3,4-DIHYDRO-4-OXO-3-((5-TRIFLUOROMETHYL-2-BENZOTHIAZOLYL)METHYL)-1-PHTHALAZINE ACETIC ACID	OC(=O)CC1=NN(CC2=NC3=C(S2)C=CC(=C3)C(F)(F)F)C(=O)C2=C1C=CC=C2
AKR1C1	DB00157	aldo-keto reductase family 1, member C1	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
AKR1C1	DB00936	aldo-keto reductase family 1, member C1	approved	Salicyclic acid	OC(=O)C1=CC=CC=C1O
AKR1C1	DB00945	aldo-keto reductase family 1, member C1	approved	Acetylsalicylic acid	CC(=O)OC1=CC=CC=C1C(O)=O
AKR1C1	DB03461	aldo-keto reductase family 1, member C1	experimental	2'-Monophosphoadenosine 5'-Diphosphoribose	NC(=O)C1=CC=C[N+](=C1)[C@@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@@H]2O[C@H]([C@H](OP(O)(O)=O)[C@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@H]1O
AKR1C1	DB04674	aldo-keto reductase family 1, member C1	experimental	2-HYDROXY-3,5-DIIODOBENZOIC ACID	OC(=O)C1=C(O)C(I)=CC(I)=C1
AKR1C1	DB07768	aldo-keto reductase family 1, member C1	experimental	(10ALPHA,13ALPHA,14BETA,17ALPHA)-17-HYDROXYANDROST-4-EN-3-ONE	C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CC[C@H]2O
AKR1C1	DB07931	aldo-keto reductase family 1, member C1	experimental	4-[(1R,2S)-1-ethyl-2-(4-hydroxyphenyl)butyl]phenol	CC[C@@H]([C@@H](CC)C1=CC=C(O)C=C1)C1=CC=C(O)C=C1
AKR1C2	DB00157	aldo-keto reductase family 1, member C2	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
AKR1C2	DB01586	aldo-keto reductase family 1, member C2	approved; investigational	Ursodeoxycholic acid	C[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@@H]3[C@@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
AKR1C2	DB03461	aldo-keto reductase family 1, member C2	experimental	2'-Monophosphoadenosine 5'-Diphosphoribose	NC(=O)C1=CC=C[N+](=C1)[C@@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@@H]2O[C@H]([C@H](OP(O)(O)=O)[C@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@H]1O
AKR1C2	DB07768	aldo-keto reductase family 1, member C2	experimental	(10ALPHA,13ALPHA,14BETA,17ALPHA)-17-HYDROXYANDROST-4-EN-3-ONE	C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CC[C@H]2O
AKR1C3	DB00157	aldo-keto reductase family 1, member C3	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
AKR1C3	DB00905	aldo-keto reductase family 1, member C3	approved; investigational	Bimatoprost	CCNC(=O)CCC\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\[C@@H](O)CCC1=CC=CC=C1
AKR1C3	DB01536	aldo-keto reductase family 1, member C3	illicit; experimental	4-Androstenedione	C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CCC2=O
AKR1C3	DB01698	aldo-keto reductase family 1, member C3	experimental	Rutin	C[C@@H]1O[C@H](OC[C@@H]2O[C@H](OC3=C(OC4=CC(O)=CC(O)=C4C3=O)C3=CC=C(O)C(O)=C3)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O
AKR1C3	DB02056	aldo-keto reductase family 1, member C3	experimental	(5e,13e)-9,15-Dihydroxy-11-Oxoprosta-5,13-Dien-1-Oicacid	CCCCC[C@H](O)\C=C\[C@@H]1[C@@H](C\C=C/CCCC(O)=O)[C@@H](O)CC1=O
AKR1C3	DB02266	aldo-keto reductase family 1, member C3	experimental	Flufenamic Acid	OC(=O)C1=CC=CC=C1NC1=CC(=CC=C1)C(F)(F)F
AKR1C3	DB03461	aldo-keto reductase family 1, member C3	experimental	2'-Monophosphoadenosine 5'-Diphosphoribose	NC(=O)C1=CC=C[N+](=C1)[C@@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@@H]2O[C@H]([C@H](OP(O)(O)=O)[C@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@H]1O
AKR1C3	DB07700	aldo-keto reductase family 1, member C3	experimental	3-CARBOXAMIDO-1,3,5(10)-ESTRATRIEN-17(R)-SPIRO-2'(5',5'-DIMETHYL-6'OXO)TETRAHYDROPYRAN	C[C@]12CC[C@H]3[C@@H](CCC4=CC(=CC=C34)C(N)=O)[C@@H]1CC[C@@]21CCC(C)(C)C(=O)O1
AKR1C3	DB00997	aldo-keto reductase family 1, member C3	approved; investigational	Doxorubicin	COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3O[C@H]3C[C@H](N)[C@H](O)[C@H](C)O3)C(=O)CO)C(O)=C1C2=O
AKR1C3	DB00482	aldo-keto reductase family 1, member C3	approved; investigational	Celecoxib	CC1=CC=C(C=C1)C1=CC(=NN1C1=CC=C(C=C1)S(N)(=O)=O)C(F)(F)F
AKR1C4	DB00157	aldo-keto reductase family 1, member C4	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
AKR1C4	DB00145	aldo-keto reductase family 1, member C4	approved; nutraceutical	Glycine	NCC(O)=O
AKR1D1	DB00548	aldo-keto reductase family 1, member D1	approved	Azelaic Acid	OC(=O)CCCCCCCC(O)=O
AKR1D1	DB01216	aldo-keto reductase family 1, member D1	approved	Finasteride	CC(C)(C)NC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4NC(=O)C=C[C@]4(C)[C@H]3CC[C@]12C
AKR1D1	DB07447	aldo-keto reductase family 1, member D1	experimental	5-beta-DIHYDROTESTOSTERONE	C[C@]12CC[C@H]3[C@@H](CC[C@@H]4CC(=O)CC[C@]34C)[C@@H]1CC[C@@H]2O
AKR1D1	DB07557	aldo-keto reductase family 1, member D1	experimental	(5BETA)-PREGNANE-3,20-DIONE	CC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C
AKR1D1	DB00145	aldo-keto reductase family 1, member D1	approved; nutraceutical	Glycine	NCC(O)=O
AKT1	DB00171	v-akt murine thymoma viral oncogene homolog 1	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
AKT1	DB01169	v-akt murine thymoma viral oncogene homolog 1	approved; investigational	Arsenic trioxide	O1[As]2O[As]1O2
AKT1	DB01863	v-akt murine thymoma viral oncogene homolog 1	experimental	Inositol 1,3,4,5-Tetrakisphosphate	O[C@H]1[C@H](OP(O)(O)=O)[C@@H](O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@@H]1OP(O)(O)=O
AKT1	DB07584	v-akt murine thymoma viral oncogene homolog 1	experimental	N-[2-(5-methyl-4H-1,2,4-triazol-3-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine	CC1=NN=C(N1)C1=CC=CC=C1NC1=NC=NC2=C1C=CN2
AKT1	DB07585	v-akt murine thymoma viral oncogene homolog 1	experimental	5-(5-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine	ClC1=CNC2=C1C(=NC=N2)N1CCC2=C(C1)N=CN2
AKT1	DB00398	v-akt murine thymoma viral oncogene homolog 1	approved; investigational	Sorafenib	CNC(=O)C1=NC=CC(OC2=CC=C(NC(=O)NC3=CC(=C(Cl)C=C3)C(F)(F)F)C=C2)=C1
AKT1	DB00864	v-akt murine thymoma viral oncogene homolog 1	approved; investigational	Tacrolimus	CO[C@@H]1C[C@@H](CC[C@H]1O)\C=C(/C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H]([C@H](C[C@H]2C)OC)[C@H](C[C@@H](C)C\C(C)=C\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]1C)OC
AKT1	DB00675	v-akt murine thymoma viral oncogene homolog 1	approved	Tamoxifen	CC\C(=C(/C1=CC=CC=C1)C1=CC=C(OCCN(C)C)C=C1)C1=CC=CC=C1
AKT1	DB00734	v-akt murine thymoma viral oncogene homolog 1	approved; investigational	Risperidone	CC1=C(CCN2CCC(CC2)C2=NOC3=C2C=CC(F)=C3)C(=O)N2CCCCC2=N1
AKT1	DB00997	v-akt murine thymoma viral oncogene homolog 1	approved; investigational	Doxorubicin	COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3O[C@H]3C[C@H](N)[C@H](O)[C@H](C)O3)C(=O)CO)C(O)=C1C2=O
AKT1	DB00317	v-akt murine thymoma viral oncogene homolog 1	approved; investigational	Gefitinib	COC1=C(OCCCN2CCOCC2)C=C2C(NC3=CC(Cl)=C(F)C=C3)=NC=NC2=C1
AKT1	DB01259	v-akt murine thymoma viral oncogene homolog 1	approved; investigational	Lapatinib	CS(=O)(=O)CCNCC1=CC=C(O1)C1=CC2=C(C=C1)N=CN=C2NC1=CC(Cl)=C(OCC2=CC(F)=CC=C2)C=C1
AKT1	DB00360	v-akt murine thymoma viral oncogene homolog 1	approved; investigational	Tetrahydrobiopterin	CC(O)C(O)C1CNC2=C(N1)C(=O)N=C(N)N2
AKT1	DB00394	v-akt murine thymoma viral oncogene homolog 1	approved	Beclomethasone	C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
AKT1	DB00443	v-akt murine thymoma viral oncogene homolog 1	approved	Betamethasone	C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
AKT1	DB01222	v-akt murine thymoma viral oncogene homolog 1	approved; investigational	Budesonide	CCC[C@H]1O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO
AKT1	DB01410	v-akt murine thymoma viral oncogene homolog 1	approved; investigational	Ciclesonide	CC(C)C(=O)OCC(=O)[C@@]12OC(O[C@@H]1C[C@H]1[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@]21C)C1CCCCC1
AKT1	DB01260	v-akt murine thymoma viral oncogene homolog 1	approved; investigational	Desonide	CC1(C)O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO
AKT1	DB01234	v-akt murine thymoma viral oncogene homolog 1	approved; investigational	Dexamethasone	C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
AKT1	DB00180	v-akt murine thymoma viral oncogene homolog 1	approved; investigational	Flunisolide	CC1(C)O[C@@H]2C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO
AKT1	DB00588	v-akt murine thymoma viral oncogene homolog 1	approved; investigational	Fluticasone Propionate	CCC(=O)O[C@@]1([C@H](C)C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)C(=O)SCF
AKT1	DB00741	v-akt murine thymoma viral oncogene homolog 1	approved	Hydrocortisone	C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
AKT1	DB00959	v-akt murine thymoma viral oncogene homolog 1	approved	Methylprednisolone	C[C@H]1C[C@H]2[C@@H]3CC[C@](O)(C(=O)CO)[C@@]3(C)C[C@H](O)[C@@H]2[C@@]2(C)C=CC(=O)C=C12
AKT1	DB00764	v-akt murine thymoma viral oncogene homolog 1	approved	Mometasone	C[C@@H]1C[C@H]2C3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CCl
AKT1	DB01384	v-akt murine thymoma viral oncogene homolog 1	approved	Paramethasone	C[C@@H]1C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
AKT1	DB00860	v-akt murine thymoma viral oncogene homolog 1	approved	Prednisolone	C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
AKT1	DB00635	v-akt murine thymoma viral oncogene homolog 1	approved	Prednisone	C[C@]12CC(=O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
AKT1	DB00896	v-akt murine thymoma viral oncogene homolog 1	approved	Rimexolone	CCC(=O)[C@@]1(C)[C@H](C)CC2C3CCC4=CC(=O)C=C[C@]4(C)C3[C@@H](O)C[C@]12C
AKT1	DB00620	v-akt murine thymoma viral oncogene homolog 1	approved	Triamcinolone	C[C@]12C[C@H](O)[C@@]3(F)[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1C[C@@H](O)[C@]2(O)C(=O)CO
AKT1	DB00877	v-akt murine thymoma viral oncogene homolog 1	approved; investigational	Sirolimus	CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1O
AKT1	DB00143	v-akt murine thymoma viral oncogene homolog 1	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
AKT1	DB00122	v-akt murine thymoma viral oncogene homolog 1	approved; nutraceutical	Choline	C[N+](C)(C)CCO
AKT1	DB00125	v-akt murine thymoma viral oncogene homolog 1	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
AKT1	DB00155	v-akt murine thymoma viral oncogene homolog 1	approved; nutraceutical	L-Citrulline	N[C@@H](CCCNC(N)=O)C(O)=O
AKT1	DB00435	v-akt murine thymoma viral oncogene homolog 1	approved	Nitric Oxide	[N]=O
AKT1	DB00131	v-akt murine thymoma viral oncogene homolog 1	approved; nutraceutical	Adenosine monophosphate	NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
AKT1	DB00619	v-akt murine thymoma viral oncogene homolog 1	approved	Imatinib	CN1CCN(CC2=CC=C(C=C2)C(=O)NC2=CC(NC3=NC=CC(=N3)C3=CN=CC=C3)=C(C)C=C2)CC1
AKT1	DB00515	v-akt murine thymoma viral oncogene homolog 1	approved	Cisplatin	N[Pt](N)(Cl)Cl
AKT1	DB00441	v-akt murine thymoma viral oncogene homolog 1	approved	Gemcitabine	NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](CO)[C@@H](O)C1(F)F
AKT1	DB00482	v-akt murine thymoma viral oncogene homolog 1	approved; investigational	Celecoxib	CC1=CC=C(C=C1)C1=CC(=NN1C1=CC=C(C=C1)S(N)(=O)=O)C(F)(F)F
AKT1	DB00184	v-akt murine thymoma viral oncogene homolog 1	approved	Nicotine	CN1CCCC1C1=CN=CC=C1
AKT1	DB01132	v-akt murine thymoma viral oncogene homolog 1	approved; investigational	Pioglitazone	CCC1=CN=C(CCOC2=CC=C(CC3SC(=O)NC3=O)C=C2)C=C1
AKT1	DB00412	v-akt murine thymoma viral oncogene homolog 1	approved; investigational	Rosiglitazone	CN(CCOC1=CC=C(CC2SC(=O)NC2=O)C=C1)C1=CC=CC=N1
ALAD	DB00855	aminolevulinate dehydratase	approved	Aminolevulinic acid	NCC(=O)CCC(O)=O
ALAD	DB02068	aminolevulinate dehydratase	experimental	Delta-Amino Valeric Acid	[NH3+]CCCCC(O)=O
ALAD	DB02239	aminolevulinate dehydratase	experimental	Laevulinic Acid	CC(=O)CCC(O)=O
ALAD	DB02260	aminolevulinate dehydratase	experimental	4-Oxosebacic Acid	OC(=O)CCCCCC(=O)CCC(O)=O
ALAD	DB02272	aminolevulinate dehydratase	experimental	Porphobilinogen	NCc1ncc(CCC(O)=O)c1CC(O)=O
ALAD	DB02878	aminolevulinate dehydratase	experimental	3-(2-Aminoethyl)-4-(Aminomethyl)Heptanedioic Acid	NCC[C@@H](CC(O)=O)[C@@H](CN)CCC(O)=O
ALAD	DB04560	aminolevulinate dehydratase	experimental	4,7-Dioxosebacic Acid	OC(=O)CCC(=O)CCC(=O)CCC(O)=O
ALAD	DB04781	aminolevulinate dehydratase	experimental	5-hydroxyvaleric acid	OCCCCC(O)=O
ALAD	DB01942	aminolevulinate dehydratase	experimental	Formic Acid	OC=O
ALAD	DB02828	aminolevulinate dehydratase	experimental	5-Fluorolevulinic Acid	OC(=O)CCC(=O)CF
ALAD	DB04530	aminolevulinate dehydratase	experimental	S,S-(2-Hydroxyethyl)Thiocysteine	N[C@@H](CSSCCO)C(O)=O
ALAD	DB00145	aminolevulinate dehydratase	approved; nutraceutical	Glycine	NCC(O)=O
ALAS1	DB00114	aminolevulinate, delta-, synthase 1	nutraceutical	Pyridoxal Phosphate	CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O
ALAS1	DB00145	aminolevulinate, delta-, synthase 1	approved; nutraceutical	Glycine	NCC(O)=O
ALAS2	DB00145	aminolevulinate, delta-, synthase 2	approved; nutraceutical	Glycine	NCC(O)=O
ALAS2	DB00114	aminolevulinate, delta-, synthase 2	nutraceutical	Pyridoxal Phosphate	CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O
ALB	DB00145	albumin	approved; nutraceutical	Glycine	NCC(O)=O
ALDH18A1	DB00142	aldehyde dehydrogenase 18 family, member A1	approved; nutraceutical	L-Glutamic Acid	N[C@@H](CCC(O)=O)C(O)=O
ALDH1A1	DB00157	aldehyde dehydrogenase 1 family, member A1	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
ALDH1A1	DB00162	aldehyde dehydrogenase 1 family, member A1	approved; nutraceutical	Vitamin A	CC(=CCO)C=CC=C(C)C=CC1=C(C)CCCC1(C)C
ALDH1A1	DB00755	aldehyde dehydrogenase 1 family, member A1	approved; nutraceutical; investigational	Tretinoin	CC(C=CC1=C(C)CCCC1(C)C)=CC=CC(C)=CC(O)=O
ALDH1A1	DB01907	aldehyde dehydrogenase 1 family, member A1	experimental	Nicotinamide-Adenine-Dinucleotide	NC(=O)C1=CC=C[N+](=C1)[C@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@@H]1O
ALDH1A1	DB04447	aldehyde dehydrogenase 1 family, member A1	experimental	1,4-Dithiothreitol	O[C@H](CS)[C@H](O)CS
ALDH1A1	DB00958	aldehyde dehydrogenase 1 family, member A1	approved	Carboplatin	N.N.O=C1O[Pt]OC(=O)C11CCC1
ALDH1A1	DB04572	aldehyde dehydrogenase 1 family, member A1	approved	Thiotepa	S=P(N1CC1)(N1CC1)N1CC1
ALDH1A1	DB00531	aldehyde dehydrogenase 1 family, member A1	approved; investigational	Cyclophosphamide	ClCCN(CCCl)P1(=O)NCCCO1
ALDH1A2	DB00157	aldehyde dehydrogenase 1 family, member A2	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
ALDH1A2	DB00162	aldehyde dehydrogenase 1 family, member A2	approved; nutraceutical	Vitamin A	CC(=CCO)C=CC=C(C)C=CC1=C(C)CCCC1(C)C
ALDH1A2	DB00755	aldehyde dehydrogenase 1 family, member A2	approved; nutraceutical; investigational	Tretinoin	CC(C=CC1=C(C)CCCC1(C)C)=CC=CC(C)=CC(O)=O
ALDH1A2	DB01907	aldehyde dehydrogenase 1 family, member A2	experimental	Nicotinamide-Adenine-Dinucleotide	NC(=O)C1=CC=C[N+](=C1)[C@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@@H]1O
ALDH1A3	DB00157	aldehyde dehydrogenase 1 family, member A3	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
ALDH1A3	DB00162	aldehyde dehydrogenase 1 family, member A3	approved; nutraceutical	Vitamin A	CC(=CCO)C=CC=C(C)C=CC1=C(C)CCCC1(C)C
ALDH1B1	DB00157	aldehyde dehydrogenase 1 family, member B1	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
ALDH2	DB00157	aldehyde dehydrogenase 2 family (mitochondrial)	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
ALDH2	DB00536	aldehyde dehydrogenase 2 family (mitochondrial)	approved	Guanidine	NC(N)=N
ALDH2	DB00822	aldehyde dehydrogenase 2 family (mitochondrial)	approved	Disulfiram	CCN(CC)C(=S)SSC(=S)N(CC)CC
ALDH2	DB01907	aldehyde dehydrogenase 2 family (mitochondrial)	experimental	Nicotinamide-Adenine-Dinucleotide	NC(=O)C1=CC=C[N+](=C1)[C@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@@H]1O
ALDH2	DB02115	aldehyde dehydrogenase 2 family (mitochondrial)	experimental	Daidzin	OC[C@H]1O[C@@H](OC2=CC=C3C(=O)C(=COC3=C2)C2=CC=C(O)C=C2)[C@H](O)[C@@H](O)[C@@H]1O
ALDH2	DB04381	aldehyde dehydrogenase 2 family (mitochondrial)	experimental	Crotonaldehyde	C\C=C\C=O
ALDH2	DB00325	aldehyde dehydrogenase 2 family (mitochondrial)	approved	Nitroprusside	O=N[Fe--](C#N)(C#N)(C#N)(C#N)C#N
ALDH2	DB00727	aldehyde dehydrogenase 2 family (mitochondrial)	approved; investigational	Nitroglycerin	[O-][N+](=O)OCC(CO[N+]([O-])=O)O[N+]([O-])=O
ALDH2	DB00898	aldehyde dehydrogenase 2 family (mitochondrial)	approved	Ethanol	CCO
ALDH3A1	DB00157	aldehyde dehydrogenase 3 family, member A1	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
ALDH3A1	DB01907	aldehyde dehydrogenase 3 family, member A1	experimental	Nicotinamide-Adenine-Dinucleotide	NC(=O)C1=CC=C[N+](=C1)[C@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@@H]1O
ALDH3A1	DB00958	aldehyde dehydrogenase 3 family, member A1	approved	Carboplatin	N.N.O=C1O[Pt]OC(=O)C11CCC1
ALDH3A1	DB04572	aldehyde dehydrogenase 3 family, member A1	approved	Thiotepa	S=P(N1CC1)(N1CC1)N1CC1
ALDH3A1	DB00531	aldehyde dehydrogenase 3 family, member A1	approved; investigational	Cyclophosphamide	ClCCN(CCCl)P1(=O)NCCCO1
ALDH3A2	DB00157	aldehyde dehydrogenase 3 family, member A2	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
ALDH3B1	DB00157	aldehyde dehydrogenase 3 family, member B1	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
ALDH3B2	DB00157	aldehyde dehydrogenase 3 family, member B2	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
ALDH4A1	DB00157	aldehyde dehydrogenase 4 family, member A1	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
ALDH4A1	DB00172	aldehyde dehydrogenase 4 family, member A1	approved; nutraceutical	L-Proline	OC(=O)[C@@H]1CCCN1
ALDH5A1	DB00139	aldehyde dehydrogenase 5 family, member A1	approved; nutraceutical	Succinic acid	OC(=O)CCC(O)=O
ALDH5A1	DB00157	aldehyde dehydrogenase 5 family, member A1	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
ALDH5A1	DB00534	aldehyde dehydrogenase 5 family, member A1	approved	Chlormerodrin	COC(CNC(N)=O)C[Hg]Cl
ALDH6A1	DB00157	aldehyde dehydrogenase 6 family, member A1	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
ALDH6A1	DB00161	aldehyde dehydrogenase 6 family, member A1	approved; nutraceutical	L-Valine	CC(C)[C@H](N)C(O)=O
ALDH7A1	DB00157	aldehyde dehydrogenase 7 family, member A1	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
ALDH7A1	DB00165	aldehyde dehydrogenase 7 family, member A1	approved; nutraceutical	Pyridoxine	CC1=NC=C(CO)C(CO)=C1O
ALDH7A1	DB00515	aldehyde dehydrogenase 7 family, member A1	approved	Cisplatin	N[Pt](N)(Cl)Cl
ALDH9A1	DB00157	aldehyde dehydrogenase 9 family, member A1	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
ALDH9A1	DB01907	aldehyde dehydrogenase 9 family, member A1	experimental	Nicotinamide-Adenine-Dinucleotide	NC(=O)C1=CC=C[N+](=C1)[C@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@@H]1O
ALDH9A1	DB00145	aldehyde dehydrogenase 9 family, member A1	approved; nutraceutical	Glycine	NCC(O)=O
ALDOA	DB02512	aldolase A, fructose-bisphosphate	experimental	1,6-Fructose Diphosphate (Linear Form)	O[C@H](COP(O)(O)=O)[C@H](O)[C@H](O)C(=O)COP(O)(O)=O
ALDOA	DB04326	aldolase A, fructose-bisphosphate	experimental	1,3-Dihydroxyacetonephosphate	OCC(=O)COP(O)(O)=O
ALDOA	DB04733	aldolase A, fructose-bisphosphate	experimental	1,6-DI-O-PHOSPHONO-D-MANNITOL	O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@H](O)COP(O)(O)=O
ALDOA	DB08240	aldolase A, fructose-bisphosphate	experimental	N-(4-CHLOROPHENYL)-3-(PHOSPHONOOXY)NAPHTHALENE-2-CARBOXAMIDE	OP(O)(=O)OC1=C(C=C2C=CC=CC2=C1)C(=O)NC1=CC=C(Cl)C=C1
ALDOA	DB00286	aldolase A, fructose-bisphosphate	approved	Conjugated Estrogens	[Na+].C[C@]12CC[C@H]3[C@@H](CCC4=CC(OS([O-])(=O)=O)=CC=C34)[C@@H]1CCC2=O
ALDOA	DB00890	aldolase A, fructose-bisphosphate	approved	Dienestrol	CC=C(C(=CC)C1=CC=C(O)C=C1)C1=CC=C(O)C=C1
ALDOA	DB00255	aldolase A, fructose-bisphosphate	approved	Diethylstilbestrol	CCC(=C(CC)C1=CC=C(O)C=C1)C1=CC=C(O)C=C1
ALDOA	DB00783	aldolase A, fructose-bisphosphate	approved; investigational	Estradiol	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CC[C@@H]2O
ALDOA	DB00655	aldolase A, fructose-bisphosphate	approved	Estrone	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CCC2=O
ALDOA	DB00269	aldolase A, fructose-bisphosphate	approved	Chlorotrianisene	COC1=CC=C(C=C1)C(Cl)=C(C1=CC=C(OC)C=C1)C1=CC=C(OC)C=C1
ALDOA	DB00977	aldolase A, fructose-bisphosphate	approved	Ethinyl Estradiol	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CC[C@@]2(O)C#C
ALOX5	DB00163	arachidonate 5-lipoxygenase	approved; nutraceutical	Vitamin E	CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCC2=C(O1)C(C)=C(C)C(O)=C2C
ALOX5	DB00179	arachidonate 5-lipoxygenase	approved	Masoprocol	C[C@@H](CC1=CC(O)=C(O)C=C1)[C@H](C)CC1=CC(O)=C(O)C=C1
ALOX5	DB00233	arachidonate 5-lipoxygenase	approved	Aminosalicylic Acid	NC1=CC(O)=C(C=C1)C(O)=O
ALOX5	DB00244	arachidonate 5-lipoxygenase	approved	Mesalazine	NC1=CC(C(O)=O)=C(O)C=C1
ALOX5	DB00471	arachidonate 5-lipoxygenase	approved	Montelukast	OC(=O)CC1(CC1)CS[C@H](CCC1=CC=CC=C1C(O)(C)C)C1=CC=CC(\C=C\C2=NC3=C(C=CC(Cl)=C3)C=C2)=C1
ALOX5	DB00586	arachidonate 5-lipoxygenase	approved	Diclofenac	OC(=O)CC1=CC=CC=C1NC1=C(Cl)C=CC=C1Cl
ALOX5	DB00711	arachidonate 5-lipoxygenase	approved	Diethylcarbamazine	CCN(CC)C(=O)N1CCN(C)CC1
ALOX5	DB00744	arachidonate 5-lipoxygenase	approved; investigational	Zileuton	CC(N(O)C(N)=O)C1=CC2=CC=CC=C2S1
ALOX5	DB00795	arachidonate 5-lipoxygenase	approved	Sulfasalazine	OC(=O)C1=CC(=CC=C1O)\N=N\C1=CC=C(C=C1)S(=O)(=O)NC1=NC=CC=C1
ALOX5	DB00939	arachidonate 5-lipoxygenase	approved	Meclofenamic acid	CC1=C(Cl)C(NC2=CC=CC=C2C(O)=O)=C(Cl)C=C1
ALOX5	DB01014	arachidonate 5-lipoxygenase	approved; investigational	Balsalazide	OC(=O)CCNC(=O)C1=CC=C(N\N=C2\C=CC(=O)C(=C2)C(O)=O)C=C1
ALOX5	DB01017	arachidonate 5-lipoxygenase	approved; investigational	Minocycline	CN(C)[C@@H]1C(=O)\C(=C(/O)N)C(=O)[C@]2(O)[C@H]1C[C@@H]1CC3=C(N(C)C)C=CC(O)=C3C(O)=C1C2=O
ALOX5	DB01097	arachidonate 5-lipoxygenase	approved; investigational	Leflunomide	CC1=C(C=NO1)C(=O)NC1=CC=C(C=C1)C(F)(F)F
ALOX5	DB01892	arachidonate 5-lipoxygenase	nutraceutical	Hyperforin	CC(C)C(=O)C12C(O)=C(CC=C(C)C)C(=O)C(CC=C(C)C)(CC(CC=C(C)C)C1(C)CCC=C(C)C)C2=O
ALOX5	DB03014	arachidonate 5-lipoxygenase	experimental	Heme	CC1=C(CCC(O)=O)C2=CC3=[N+]4C(=CC5=C(C=C)C(C)=C6C=C7C(C=C)=C(C)C8=[N+]7[Fe@]4(N2C1=C8)N56)C(C)=C3CCC(O)=O
ALOX5	DB00143	arachidonate 5-lipoxygenase	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
ALOX5	DB00145	arachidonate 5-lipoxygenase	approved; nutraceutical	Glycine	NCC(O)=O
ALOX5	DB00917	arachidonate 5-lipoxygenase	approved	Dinoprostone	CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O
ALOX5	DB01240	arachidonate 5-lipoxygenase	approved	Epoprostenol	CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)C[C@@H]2OC(C[C@H]12)=CCCCC(O)=O
ALOX5	DB00549	arachidonate 5-lipoxygenase	approved; investigational	Zafirlukast	COC1=C(CC2=CN(C)C3=C2C=C(NC(=O)OC2CCCC2)C=C3)C=CC(=C1)C(=O)NS(=O)(=O)C1=CC=CC=C1C
AMACR	DB00145	alpha-methylacyl-CoA racemase	approved; nutraceutical	Glycine	NCC(O)=O
AMD1	DB00118	adenosylmethionine decarboxylase 1	approved; nutraceutical	S-Adenosylmethionine	C[S+](CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C(N)N=CN=C12
AMD1	DB01917	adenosylmethionine decarboxylase 1	experimental	Putrescine	NCCCCN
AMD1	DB03754	adenosylmethionine decarboxylase 1	experimental	Tris(Hydroxymethyl)Aminomethane	[NH3+]C(CO)(CO)CO
AMD1	DB08163	adenosylmethionine decarboxylase 1	experimental	5'-{[4-(aminooxy)butyl](methyl)amino}-5'-deoxy-8-ethenyladenosine	CN(CCCCON)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C(C=C)=NC2=C(N)N=CN=C12
AMD1	DB00134	adenosylmethionine decarboxylase 1	approved; nutraceutical	L-Methionine	CSCC[C@H](N)C(O)=O
AMDHD1	DB00117	amidohydrolase domain containing 1	approved; nutraceutical	L-Histidine	N[C@@H](CC1=CN=CN1)C(O)=O
AMN	DB00200	amnion associated transmembrane protein	approved	Hydroxocobalamin	C([C@@H]1[C@]2(CCC(NC[C@H](OP(O[C@@H]3[C@H](O[C@@H]([C@@H]3O)N3C=[N]([Co+]456([N]7=C8C=C9[N]4=C(C(C)=C2N5[C@H]1[C@@]1([N]6=C(C(C)=C7[C@@](CC(N)=O)([C@@H]8CCC(N)=O)C)[C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)C)[C@H](C9(C)C)CCC(N)=O)O)C1=CC(=C(C=C31)C)C)CO)([O-])=O)C)=O)C)C(N)=O
AMPD1	DB00173	adenosine monophosphate deaminase 1	approved; nutraceutical	Adenine	NC1=C2NC=NC2=NC=N1
AMPD1	DB00640	adenosine monophosphate deaminase 1	approved; investigational	Adenosine	NC1=C2N=CN([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)C2=NC=N1
AMPD1	DB00158	adenosine monophosphate deaminase 1	approved; nutraceutical	Folic Acid	NC1=NC(=O)C2=NC(CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)=CN=C2N1
AMPD1	DB01076	adenosine monophosphate deaminase 1	approved	Atorvastatin	CC(C)C1=C(C(=O)NC2=CC=CC=C2)C(=C(N1CC[C@@H](O)C[C@@H](O)CC(O)=O)C1=CC=C(F)C=C1)C1=CC=CC=C1
AMPD1	DB00439	adenosine monophosphate deaminase 1	withdrawn	Cerivastatin	COCC1=C(C2=CC=C(F)C=C2)C(\C=C\[C@@H](O)C[C@@H](O)CC(O)=O)=C(C(C)C)N=C1C(C)C
AMPD1	DB01095	adenosine monophosphate deaminase 1	approved	Fluvastatin	CC(C)N1C(\C=C\[C@H](O)C[C@H](O)CC(O)=O)=C(C2=CC=C(F)C=C2)C2=CC=CC=C12
AMPD1	DB00175	adenosine monophosphate deaminase 1	approved	Pravastatin	CC[C@H](C)C(=O)O[C@H]1C[C@H](O)C=C2C=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC(O)=O)[C@@H]12
AMPD1	DB01098	adenosine monophosphate deaminase 1	approved	Rosuvastatin	CC(C)C1=NC(=NC(C2=CC=C(F)C=C2)=C1\C=C\[C@H](O)C[C@@H](O)CC(O)=O)N(C)S(=O)(=O)C
AMPD1	DB00641	adenosine monophosphate deaminase 1	approved	Simvastatin	CCC(C)(C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CCC3C[C@@H](O)CC(=O)O3)[C@@H]12
AMPD1	DB00563	adenosine monophosphate deaminase 1	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
AMPD2	DB00173	adenosine monophosphate deaminase 2	approved; nutraceutical	Adenine	NC1=C2NC=NC2=NC=N1
AMPD2	DB00640	adenosine monophosphate deaminase 2	approved; investigational	Adenosine	NC1=C2N=CN([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)C2=NC=N1
AMPD3	DB00173	adenosine monophosphate deaminase 3	approved; nutraceutical	Adenine	NC1=C2NC=NC2=NC=N1
AMPD3	DB00640	adenosine monophosphate deaminase 3	approved; investigational	Adenosine	NC1=C2N=CN([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)C2=NC=N1
AMT	DB00116	aminomethyltransferase	approved; nutraceutical	Tetrahydrofolic acid	NC1=NC(=O)C2=C(NCC(CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)N2)N1
AMT	DB00157	aminomethyltransferase	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
AMT	DB04789	aminomethyltransferase	experimental	5-methyltetrahydrofolate	CN1[C@@H](CNC2=CC=C(C=C2)C(=O)N[C@@H](CCC(O)=O)C(O)=O)CNC2=C1C(=O)N=C(N)N2
AMT	DB00563	aminomethyltransferase	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
AMY1A	DB02379	amylase, alpha 1A (salivary)	experimental	Beta-D-Glucose	OC[C@@H]1O[C@H](O)[C@@H](O)[C@H](O)[C@H]1O
AMY1A	DB03088	amylase, alpha 1A (salivary)	experimental	Pyroglutamic Acid	OC(=O)[C@H]1CCC(=O)N1
AMY1A	DB03092	amylase, alpha 1A (salivary)	experimental	5-Hydroxymethyl-Chonduritol	OCC1=C[C@H](O)[C@@H](O)[C@H](O)[C@H]1O
AMY1A	DB03439	amylase, alpha 1A (salivary)	experimental	4,6-Dideoxy-4-Amino-Alpha-D-Glucose	C[C@@H]1O[C@H](O)[C@@H](O)[C@H](O)[C@H]1N
AMY1A	DB04237	amylase, alpha 1A (salivary)	experimental	Tris(Hydroxyethyl)Aminomethane	NC(CCO)(CCO)CCO
AMY1A	DB00218	amylase, alpha 1A (salivary)	approved; investigational	Moxifloxacin	COC1=C2N(C=C(C(O)=O)C(=O)C2=CC(F)=C1N1C[C@@H]2CCCN[C@@H]2C1)C1CC1
AMY2A	DB00284	amylase, alpha 2A (pancreatic)	approved; investigational	Acarbose	C[C@H]1O[C@H](O[C@@H]2[C@@H](CO)O[C@H](O[C@@H]3[C@@H](CO)O[C@@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1N[C@H]1C=C(CO)[C@H](O)[C@H](O)[C@H]1O
AMY2A	DB01922	amylase, alpha 2A (pancreatic)	experimental	Maltosyl-Alpha (1,4)-D-Gluconhydroximo-1,5-Lactam	OC[C@H]1N\C(=N/O)[C@@H](O)[C@@H](O)[C@H]1O[C@@H]1O[C@H](CO)[C@@H](O[C@H]2O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H]1O
AMY2A	DB02218	amylase, alpha 2A (pancreatic)	experimental	N-[4-Hydroxymethyl-Cyclohexan-6-Yl-1,2,3-Triol]-4,6-Dideoxy-4-Aminoglucopyranoside	C[C@@H]1O[C@H](O)[C@@H](O)[C@H](O)[C@H]1N[C@@H]1C=C(CO)[C@@H](O)[C@H](O)[C@@H]1O
AMY2A	DB02379	amylase, alpha 2A (pancreatic)	experimental	Beta-D-Glucose	OC[C@@H]1O[C@H](O)[C@@H](O)[C@H](O)[C@H]1O
AMY2A	DB02889	amylase, alpha 2A (pancreatic)	experimental	4-O-(4,6-Dideoxy-4-{[4,5,6-Trihydroxy-3-(Hydroxymethyl)Cyclohex-2-En-1-Yl]Amino}-Beta-D-Lyxo-Hexopyranosyl)-Alpha-D-Erythro-Hexopyranose	C[C@H]1O[C@@H](O[C@@H]2[C@H](CO)O[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@H]1N[C@@H]1C=C(CO)[C@@H](O)[C@H](O)[C@@H]1O
AMY2A	DB03088	amylase, alpha 2A (pancreatic)	experimental	Pyroglutamic Acid	OC(=O)[C@H]1CCC(=O)N1
AMY2A	DB03092	amylase, alpha 2A (pancreatic)	experimental	5-Hydroxymethyl-Chonduritol	OCC1=C[C@H](O)[C@@H](O)[C@H](O)[C@H]1O
AMY2A	DB03439	amylase, alpha 2A (pancreatic)	experimental	4,6-Dideoxy-4-Amino-Alpha-D-Glucose	C[C@@H]1O[C@H](O)[C@@H](O)[C@H](O)[C@H]1N
AMY2A	DB03495	amylase, alpha 2A (pancreatic)	experimental	4,6-Dideoxy-4-{[4,5,6-Trihydroxy-3-(Hydroxymethyl)Cyclohex-2-En-1-Yl]Amino}-Alpha-D-Lyxo-Hexopyranosyl-(1->4)-Alpha-D-Threo-Hexopyranosyl-(1->6)-Alpha-L-Threo-Hexopyranose	C[C@H]1O[C@@H](O[C@@H]2[C@H](CO)O[C@@H](OC[C@@H]3O[C@H](O)[C@@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@H]1N[C@@H]1C=C(CO)[C@@H](O)[C@H](O)[C@@H]1O
AMY2A	DB03773	amylase, alpha 2A (pancreatic)	experimental	6-Deoxy-Alpha-D-Glucose	C[C@@H]1O[C@H](O)[C@@H](O)[C@H](O)[C@H]1O
AMY2A	DB03971	amylase, alpha 2A (pancreatic)	experimental	Acarbose Derived Hexasaccharide	C[C@H]1O[C@@H](O[C@@H]2[C@H](CO)O[C@@H](OC[C@@H]3O[C@H](O)[C@@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1N[C@H]1C=C(CO)[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O[C@H]3O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]3O)[C@H](O)[C@H]2O)[C@@H](O)[C@@H]1O
AMY2A	DB04453	amylase, alpha 2A (pancreatic)	experimental	4-O-(4,6-Dideoxy-4-{[4-[(4-O-Hexopyranosylhexopyranosyl)Oxy]-5,6-Dihydroxy-3-(Hydroxymethyl)Cyclohex-2-En-1-Yl]Amino}Hexopyranosyl)Hexopyranose	C[C@H]1O[C@@H](O[C@@H]2[C@H](CO)O[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1N[C@H]1C=C(CO)[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O[C@H]3O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]3O)[C@H](O)[C@H]2O)[C@@H](O)[C@@H]1O
AMY2A	DB04618	amylase, alpha 2A (pancreatic)	experimental	4,6-DIDEOXY-4-{[4-[(4-O-HEXOPYRANOSYLHEXOPYRANOSYL)OXY]-5,6-DIHYDROXY-3-(HYDROXYMETHYL)CYCLOHEX-2-EN-1-YL]AMINO}HEXOPYRANOSYL-(1->4)HEXOPYRANOSYL-(1->4)HEXOPYRANOSE	C[C@H]1O[C@H](O[C@@H]2[C@@H](CO)O[C@H](O[C@@H]3[C@@H](CO)O[C@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1N[C@H]1C=C(CO)[C@@H](O[C@H]2O[C@H](CO)[C@@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O
AMY2A	DB04465	amylase, alpha 2A (pancreatic)	experimental	Lactose	OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O
ANPEP	DB00973	alanyl (membrane) aminopeptidase	approved	Ezetimibe	O[C@@H](CC[C@@H]1[C@H](N(C1=O)C1=CC=C(F)C=C1)C1=CC=C(O)C=C1)C1=CC=C(F)C=C1
ANPEP	DB06196	alanyl (membrane) aminopeptidase	approved; investigational	Icatibant	N[C@H](CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)N1CCCC1C(=O)N1C[C@H](O)CC1C(=O)NCC(=O)N[C@@H](CC1=CC=CS1)C(=O)N[C@@H](CO)C(=O)N1CC2=CC=CC=C2CC1C(=O)N1[C@H]2CCCC[C@H]2CC1C(=O)N[C@@H](CCCN=C(N)N)C(O)=O
ANPEP	DB08506	alanyl (membrane) aminopeptidase	experimental	N-{(2S)-3-[(1R)-1-aminoethyl](hydroxy)phosphoryl-2-benzylpropanoyl}-L-phenylalanine	C[C@H](N)[P@@](O)(=O)C[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC1=CC=CC=C1)C(O)=O
ANPEP	DB00563	alanyl (membrane) aminopeptidase	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
ANPEP	DB00987	alanyl (membrane) aminopeptidase	approved; investigational	Cytarabine	NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O
AOC3	DB00780	amine oxidase, copper containing 3	approved	Phenelzine	NNCCC1=CC=CC=C1
AOC3	DB01275	amine oxidase, copper containing 3	approved	Hydralazine	NNC1=NN=CC2=CC=CC=C12
AOC3	DB04334	amine oxidase, copper containing 3	experimental	6-hydroxydopa quinone	N[C@@H](CC1=CC(=O)C(O)=CC1=O)C(O)=O
AOX1	DB00993	aldehyde oxidase 1	approved	Azathioprine	CN1C=NC(=C1SC1=NC=NC2=C1NC=N2)[N+]([O-])=O
AOX1	DB00437	aldehyde oxidase 1	approved	Allopurinol	O=C1N=CN=C2NNC=C12
AOX1	DB00170	aldehyde oxidase 1	approved; nutraceutical	Menadione	CC1=CC(=O)C2=CC=CC=C2C1=O
AOX1	DB00563	aldehyde oxidase 1	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
AOX1	DB00352	aldehyde oxidase 1	approved	Thioguanine	NC1=NC(=S)C2=C(N1)N=CN2
APOA1	DB01039	apolipoprotein A-I	approved	Fenofibrate	CC(C)OC(=O)C(C)(C)OC1=CC=C(C=C1)C(=O)C1=CC=C(Cl)C=C1
APOA1	DB00503	apolipoprotein A-I	approved; investigational	Ritonavir	CC(C)[C@H](NC(=O)N(C)CC1=CSC(=N1)C(C)C)C(=O)N[C@H](C[C@H](O)[C@H](CC1=CC=CC=C1)NC(=O)OCC1=CN=CS1)CC1=CC=CC=C1
APOA1	DB00624	apolipoprotein A-I	approved; investigational	Testosterone	C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CC[C@@H]2O
APOA5	DB01076	apolipoprotein A-V	approved	Atorvastatin	CC(C)C1=C(C(=O)NC2=CC=CC=C2)C(=C(N1CC[C@@H](O)C[C@@H](O)CC(O)=O)C1=CC=C(F)C=C1)C1=CC=CC=C1
APOA5	DB00227	apolipoprotein A-V	approved; investigational	Lovastatin	CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12
APOA5	DB00641	apolipoprotein A-V	approved	Simvastatin	CCC(C)(C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CCC3C[C@@H](O)CC(=O)O3)[C@@H]12
APOA5	DB00363	apolipoprotein A-V	approved	Clozapine	CN1CCN(CC1)C1=NC2=CC(Cl)=CC=C2NC2=CC=CC=C12
APOA5	DB00334	apolipoprotein A-V	approved; investigational	Olanzapine	CN1CCN(CC1)C1=C2C=C(C)SC2=NC2=CC=CC=C2N1
APOB	DB01095	apolipoprotein B	approved	Fluvastatin	CC(C)N1C(\C=C\[C@H](O)C[C@H](O)CC(O)=O)=C(C2=CC=C(F)C=C2)C2=CC=CC=C12
APOB	DB00335	apolipoprotein B	approved	Atenolol	CC(C)NCC(O)COC1=CC=C(CC(N)=O)C=C1
APOB	DB01029	apolipoprotein B	approved; investigational	Irbesartan	CCCCC1=NC2(CCCC2)C(=O)N1CC1=CC=C(C=C1)C1=CC=CC=C1C1=NNN=N1
APOB	DB00930	apolipoprotein B	approved	Colesevelam	
APOB	DB00264	apolipoprotein B	approved; investigational	Metoprolol	COCCC1=CC=C(OCC(O)CNC(C)C)C=C1
APOC3	DB00363	apolipoprotein C-III	approved	Clozapine	CN1CCN(CC1)C1=NC2=CC(Cl)=CC=C2NC2=CC=CC=C12
APOC3	DB00334	apolipoprotein C-III	approved; investigational	Olanzapine	CN1CCN(CC1)C1=C2C=C(C)SC2=NC2=CC=CC=C2N1
APOC3	DB00503	apolipoprotein C-III	approved; investigational	Ritonavir	CC(C)[C@H](NC(=O)N(C)CC1=CSC(=N1)C(C)C)C(=O)N[C@H](C[C@H](O)[C@H](CC1=CC=CC=C1)NC(=O)OCC1=CN=CS1)CC1=CC=CC=C1
APOE	DB01095	apolipoprotein E	approved	Fluvastatin	CC(C)N1C(\C=C\[C@H](O)C[C@H](O)CC(O)=O)=C(C2=CC=C(F)C=C2)C2=CC=CC=C12
APOE	DB00459	apolipoprotein E	approved	Acitretin	COC1=C(C)C(C)=C(\C=C\C(\C)=C\C=C\C(\C)=C/C(O)=O)C(C)=C1
APOE	DB00175	apolipoprotein E	approved	Pravastatin	CC[C@H](C)C(=O)O[C@H]1C[C@H](O)C=C2C=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC(O)=O)[C@@H]12
APOE	DB01241	apolipoprotein E	approved	Gemfibrozil	CC1=CC(OCCCC(C)(C)C(O)=O)=C(C)C=C1
APOE	DB00989	apolipoprotein E	approved; investigational	Rivastigmine	CCN(C)C(=O)OC1=CC=CC(=C1)[C@H](C)N(C)C
APOE	DB00412	apolipoprotein E	approved; investigational	Rosiglitazone	CN(CCOC1=CC=C(CC2SC(=O)NC2=O)C=C1)C1=CC=CC=N1
APOE	DB01418	apolipoprotein E	approved	Acenocoumarol	CC(=O)CC(C1=CC=C(C=C1)[N+]([O-])=O)C1=C(O)OC2=CC=CC=C2C1=O
APOE	DB00982	apolipoprotein E	approved	Isotretinoin	CC(C=CC1=C(C)CCCC1(C)C)=CC=CC(C)=CC(O)=O
APOE	DB00682	apolipoprotein E	approved	Warfarin	CC(=O)CC(C1=CC=CC=C1)C1=C(O)OC2=CC=CC=C2C1=O
APOE	DB00843	apolipoprotein E	approved	Donepezil	COC1=C(OC)C=C2C(=O)C(CC3CCN(CC4=CC=CC=C4)CC3)CC2=C1
APOE	DB01039	apolipoprotein E	approved	Fenofibrate	CC(C)OC(=O)C(C)(C)OC1=CC=C(C=C1)C(=O)C1=CC=C(Cl)C=C1
APOE	DB00503	apolipoprotein E	approved; investigational	Ritonavir	CC(C)[C@H](NC(=O)N(C)CC1=CSC(=N1)C(C)C)C(=O)N[C@H](C[C@H](O)[C@H](CC1=CC=CC=C1)NC(=O)OCC1=CN=CS1)CC1=CC=CC=C1
APOE	DB00382	apolipoprotein E	approved	Tacrine	NC1=C2CCCCC2=NC2=CC=CC=C12
APOE	DB00122	apolipoprotein E	approved; nutraceutical	Choline	C[N+](C)(C)CCO
APOE	DB00641	apolipoprotein E	approved	Simvastatin	CCC(C)(C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CCC3C[C@@H](O)CC(=O)O3)[C@@H]12
APOE	DB00674	apolipoprotein E	approved	Galantamine	COC1=C2O[C@H]3C[C@@H](O)C=C[C@]33CCN(C)CC(C=C1)=C23
APOE	DB00334	apolipoprotein E	approved; investigational	Olanzapine	CN1CCN(CC1)C1=C2C=C(C)SC2=NC2=CC=CC=C2N1
APOE	DB00264	apolipoprotein E	approved; investigational	Metoprolol	COCCC1=CC=C(OCC(O)CNC(C)C)C=C1
APRT	DB00173	adenine phosphoribosyltransferase	approved; nutraceutical	Adenine	NC1=C2NC=NC2=NC=N1
APRT	DB01632	adenine phosphoribosyltransferase	experimental	Alpha-Phosphoribosylpyrophosphoric Acid	O[C@H]1[C@@H](O)[C@@H](O[P@](O)(=O)OP(O)(O)=O)O[C@@H]1COP(O)(O)=O
APRT	DB03506	adenine phosphoribosyltransferase	experimental	9-Deazaadenine	Nc1ncnc2ccnc12
APRT	DB04272	adenine phosphoribosyltransferase	experimental	Citric Acid	OC(=O)CC(O)(CC(O)=O)C(O)=O
APRT	DB00640	adenine phosphoribosyltransferase	approved; investigational	Adenosine	NC1=C2N=CN([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)C2=NC=N1
ARF1	DB02774	ADP-ribosylation factor 1	experimental	1,3-Propandiol	OCCCO
ARF1	DB04077	ADP-ribosylation factor 1	experimental	Glycerol	OCC(O)CO
ARF1	DB04121	ADP-ribosylation factor 1	experimental	Guanosine-3'-Monophosphate-5'-Diphosphate	NC1=NC2=C(N=CN2[C@@H]2O[C@@H](CO[P@](O)(=O)OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@H]2O)C(=O)N1
ARF1	DB04137	ADP-ribosylation factor 1	experimental	Guanosine-5'-Triphosphate	NC1=NC2=C(N=CN2[C@@H]2O[C@@H](CO[P@](O)(=O)O[P@@](O)(=O)OP(O)(O)=O)[C@H](O)[C@H]2O)C(=O)N1
ARF1	DB04315	ADP-ribosylation factor 1	experimental	Guanosine-5'-Diphosphate	NC1=NC2=C(N=CN2[C@@H]2O[C@@H](CO[P@](O)(=O)OP(O)(O)=O)[C@H](O)[C@H]2O)C(=O)N1
ARF1	DB07348	ADP-ribosylation factor 1	experimental	1,6,7,8,9,11A,12,13,14,14A-DECAHYDRO-1,13-DIHYDROXY-6-METHYL-4H-CYCLOPENT[F]OXACYCLOTRIDECIN-4-ONE	C[C@H]1CCC\C=C\[C@@H]2C[C@H](O)C[C@H]2[C@H](O)\C=C\C(=O)O1
ARF1	DB08231	ADP-ribosylation factor 1	experimental	MYRISTIC ACID	CCCCCCCCCCCCCC(O)=O
ARF1	DB00122	ADP-ribosylation factor 1	approved; nutraceutical	Choline	C[N+](C)(C)CCO
ARG1	DB00129	arginase, liver	approved; nutraceutical	L-Ornithine	NCCC[C@H](N)C(O)=O
ARG1	DB01983	arginase, liver	experimental	2(S)-Amino-6-Boronohexanoic Acid	N[C@@H](CCCC[B-](O)(O)O)C(O)=O
ARG1	DB02381	arginase, liver	experimental	Nor-N-Omega-Hydroxy-L-Arginine	N[C@@H](CCNC(=N)NO)C(O)=O
ARG1	DB02499	arginase, liver	experimental	Dinor-N(Omega)-Hydroxy-L-Arginine	N[C@@H](C\N=C(/N)NO)C(O)=O
ARG1	DB02689	arginase, liver	experimental	S-{2-[Amino(Dihydroxy)-Lambda~4~-Sulfanyl]Ethyl}-D-Cysteine	N[C@@H](CSCCS(N)(O)O)C(O)=O
ARG1	DB03144	arginase, liver	experimental	N-Omega-Hydroxy-L-Arginine	N[C@@H](CCCNC(=N)NO)C(O)=O
ARG1	DB03731	arginase, liver	experimental	S-2-(Boronoethyl)-L-Cysteine	N[C@@H](CSCC[B](O)(O)O)C(O)=O
ARG1	DB03904	arginase, liver	experimental	Urea	NC(N)=O
ARG1	DB04197	arginase, liver	experimental	Descarboxy-nor-N(Omega)-Hydroxy-L-Arginine	N\C(NO)=N/CCC[NH3+]
ARG1	DB04530	arginase, liver	experimental	S,S-(2-Hydroxyethyl)Thiocysteine	N[C@@H](CSSCCO)C(O)=O
ARG1	DB04585	arginase, liver	experimental	DEHYDRO-2(S)-AMINO-6-BORONOHEXANOIC ACID	N[C@@H](CC\C=C\[B-](O)(O)O)C(O)=O
ARG1	DB04648	arginase, liver	experimental	S-propylamine-L-cysteine	NCCCSC[C@H](N)CO
ARG1	DB01222	arginase, liver	approved; investigational	Budesonide	CCC[C@H]1O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO
ARG1	DB00588	arginase, liver	approved; investigational	Fluticasone Propionate	CCC(=O)O[C@@]1([C@H](C)C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)C(=O)SCF
ARG1	DB00716	arginase, liver	approved	Nedocromil	CCCC1=C2N(CC)C(=CC(=O)C2=CC2=C1OC(=CC2=O)C(O)=O)C(O)=O
ARG1	DB01001	arginase, liver	approved	Salbutamol	CC(C)(C)NCC(O)C1=CC(CO)=C(O)C=C1
ARG1	DB00125	arginase, liver	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
ARG2	DB00125	arginase 2	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
ARG2	DB00129	arginase 2	approved; nutraceutical	L-Ornithine	NCCC[C@H](N)C(O)=O
ARG2	DB03731	arginase 2	experimental	S-2-(Boronoethyl)-L-Cysteine	N[C@@H](CSCC[B](O)(O)O)C(O)=O
ARSA	DB01800	arylsulfatase A	experimental	N,4-Dihydroxy-N-Oxo-3-(Sulfooxy)Benzenaminium	OC1=CC=C(C=C1OS(O)(=O)=O)[N+]([O-])=O
ARSA	DB03821	arylsulfatase A	experimental	2-Amino-3-Hydroxy-3-Phosphonooxy-Propionic Acid	N[C@@H]([C@H](O)OP(O)(O)=O)C(O)=O
ARSE	DB00682	arylsulfatase E (chondrodysplasia punctata 1)	approved	Warfarin	CC(=O)CC(C1=CC=CC=C1)C1=C(O)OC2=CC=CC=C2C1=O
ASAH1	DB00143	N-acylsphingosine amidohydrolase (acid ceramidase) 1	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
ASL	DB00125	argininosuccinate lyase	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
ASL	DB02267	argininosuccinate lyase	experimental	Argininosuccinate	N[C@@H](CCCNC(=N)N[C@H](CC(O)=O)C(O)=O)C(O)=O
ASL	DB03814	argininosuccinate lyase	experimental	2-(N-Morpholino)-Ethanesulfonic Acid	[O-]S(=O)(=O)CC[NH+]1CCOCC1
ASL	DB03904	argininosuccinate lyase	experimental	Urea	NC(N)=O
ASMT	DB01065	acetylserotonin O-methyltransferase	approved; nutraceutical	Melatonin	COC1=CC2=C(NC=C2CCNC(C)=O)C=C1
ASMT	DB01356	acetylserotonin O-methyltransferase	approved	Lithium	[Li+]
ASNS	DB00128	asparagine synthetase (glutamine-hydrolyzing)	approved; nutraceutical	L-Aspartic Acid	N[C@@H](CC(O)=O)C(O)=O
ASNS	DB00142	asparagine synthetase (glutamine-hydrolyzing)	approved; nutraceutical	L-Glutamic Acid	N[C@@H](CCC(O)=O)C(O)=O
ASNS	DB00171	asparagine synthetase (glutamine-hydrolyzing)	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
ASNS	DB00174	asparagine synthetase (glutamine-hydrolyzing)	approved; nutraceutical	L-Asparagine	N[C@@H](CC(N)=O)C(O)=O
ASNS	DB00130	asparagine synthetase (glutamine-hydrolyzing)	approved; nutraceutical; investigational	L-Glutamine	N[C@@H](CCC(N)=O)C(O)=O
ASPA	DB00128	aspartoacylase	approved; nutraceutical	L-Aspartic Acid	N[C@@H](CC(O)=O)C(O)=O
ASS1	DB00125	argininosuccinate synthase 1	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
ASS1	DB00128	argininosuccinate synthase 1	approved; nutraceutical	L-Aspartic Acid	N[C@@H](CC(O)=O)C(O)=O
ASS1	DB00155	argininosuccinate synthase 1	approved; nutraceutical	L-Citrulline	N[C@@H](CCCNC(N)=O)C(O)=O
ASS1	DB00171	argininosuccinate synthase 1	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
ASS1	DB02267	argininosuccinate synthase 1	experimental	Argininosuccinate	N[C@@H](CCCNC(=N)N[C@H](CC(O)=O)C(O)=O)C(O)=O
ASS1	DB04395	argininosuccinate synthase 1	experimental	Phosphoaminophosphonic Acid-Adenylate Ester	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](CO[P@](O)(=O)O[P@@](O)(=O)NP(O)(O)=O)[C@H](O)[C@H]1O
ASS1	DB00536	argininosuccinate synthase 1	approved	Guanidine	NC(N)=N
ASS1	DB04077	argininosuccinate synthase 1	experimental	Glycerol	OCC(O)CO
ASS1	DB03904	argininosuccinate synthase 1	experimental	Urea	NC(N)=O
ATIC	DB00116	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase	approved; nutraceutical	Tetrahydrofolic acid	NC1=NC(=O)C2=C(NCC(CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)N2)N1
ATIC	DB00642	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase	approved; investigational	Pemetrexed	NC1=NC(=O)C2=C(NC=C2CCC2=CC=C(C=C2)C(=O)N[C@H](CCC(O)=O)C(O)=O)N1
ATIC	DB01700	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase	experimental	Aicar	NC(=O)C1=C(N)N(C=N1)[C@@H]1O[C@@H](COP(O)(O)=O)[C@H](O)[C@H]1O
ATIC	DB01972	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase	experimental	Guanosine-5'-Monophosphate	NC1=NC2=C(N=CN2[C@@H]2O[C@@H](COP(O)(O)=O)[C@H](O)[C@H]2O)C(=O)N1
ATIC	DB02309	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase	experimental	5--Monophosphate-9-Beta-D-Ribofuranosyl Xanthine	O[C@H]1[C@H](COP(O)(O)=O)O[C@H]([C@@H]1O)N1C=[NH+]C2=C1NC(=O)NC2=O
ATIC	DB03442	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase	experimental	2-[5-Hydroxy-3-Methyl-1-(2-Methyl-4-Sulfo-Phenyl)-1h-Pyrazol-4-Ylazo]-4-Sulfo-Benzoic Acid	CC1=NN(C(O)=C1\N=N\C1=CC(=CC=C1C(O)=O)S(O)(=O)=O)C1=CC=C(C=C1C)S(O)(=O)=O
ATIC	DB04057	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase	experimental	Beta-Dadf, Msa, Multisubstrate Adduct Inhibitor	O[C@@H]1[C@@H](O)[C@@H](O[C@H]1COP(O)(O)=O)N1C=NC(C(N)=O)=C1\C=C\C(=O)N(CC1=CC=C2N=C(N)NC(=O)C2=N1)C1=CC=C(C=C1)C(=O)N[C@H](CCC(O)=O)C(O)=O
ATIC	DB00145	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase	approved; nutraceutical	Glycine	NCC(O)=O
ATIC	DB00130	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase	approved; nutraceutical; investigational	L-Glutamine	N[C@@H](CCC(N)=O)C(O)=O
ATIC	DB00158	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase	approved; nutraceutical	Folic Acid	NC1=NC(=O)C2=NC(CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)=CN=C2N1
ATIC	DB00563	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
ATIC	DB00795	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase	approved	Sulfasalazine	OC(=O)C1=CC(=CC=C1O)\N=N\C1=CC=C(C=C1)S(=O)(=O)NC1=NC=CC=C1
ATIC	DB00640	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase	approved; investigational	Adenosine	NC1=C2N=CN([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)C2=NC=N1
ATP5A1	DB04216	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle	experimental	Quercetin	OC1=CC2=C(C(O)=C1)C(=O)C(O)=C(O2)C1=CC=C(O)C(O)=C1
ATP5A1	DB07384	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle	experimental	1-ACETYL-2-CARBOXYPIPERIDINE	CC(=O)N1CCCC[C@H]1C(O)=O
ATP5A1	DB07394	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle	experimental	AUROVERTIN B	CC[C@H]1O[C@]2(C)[C@H](OC(C)=O)[C@@]1(C)O[C@@H](\C=C\C=C\C=C\C1=C(C)C(OC)=CC(=O)O1)[C@@H]2O
ATP5A1	DB08399	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle	experimental	PICEATANNOL	OC1=CC(\C=C\C2=CC=C(O)C(O)=C2)=CC(O)=C1
ATP5A1	DB08629	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle	experimental	N1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINE	CC(C)C[C@H](N)CN1CCCN2CCC[C@@H]12
ATP5B	DB04216	ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide	experimental	Quercetin	OC1=CC2=C(C(O)=C1)C(=O)C(O)=C(O2)C1=CC=C(O)C(O)=C1
ATP5B	DB07384	ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide	experimental	1-ACETYL-2-CARBOXYPIPERIDINE	CC(=O)N1CCCC[C@H]1C(O)=O
ATP5B	DB07394	ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide	experimental	AUROVERTIN B	CC[C@H]1O[C@]2(C)[C@H](OC(C)=O)[C@@]1(C)O[C@@H](\C=C\C=C\C=C\C1=C(C)C(OC)=CC(=O)O1)[C@@H]2O
ATP5B	DB08399	ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide	experimental	PICEATANNOL	OC1=CC(\C=C\C2=CC=C(O)C(O)=C2)=CC(O)=C1
ATP5B	DB08629	ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide	experimental	N1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINE	CC(C)C[C@H](N)CN1CCCN2CCC[C@@H]12
AUH	DB00121	AU RNA binding protein/enoyl-CoA hydratase	approved; nutraceutical	Biotin	OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12
AUH	DB00149	AU RNA binding protein/enoyl-CoA hydratase	approved; nutraceutical	L-Leucine	CC(C)CC(N)C(O)=O
B3GAT1	DB01694	beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)	experimental	D-tartaric acid	O[C@@H]([C@@H](O)C(O)=O)C(O)=O
B3GAT1	DB03435	beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)	experimental	Uridine-5'-Diphosphate	O[C@@H]1[C@@H](O)[C@@H](O[C@H]1CO[P@](O)(=O)OP(O)(O)=O)N1C=CC(=O)NC1=O
B3GAT3	DB03041	beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)	experimental	Udp-Glucuronic Acid	O[C@H]1[C@H](CO[P@@](O)(=O)O[P@@](O)(=O)O[C@H]2O[C@H]([C@H](O)[C@@H](O)[C@@H]2O)C(O)=O)O[C@H]([C@@H]1O)N1C=CC(=O)NC1=O
B3GAT3	DB03435	beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)	experimental	Uridine-5'-Diphosphate	O[C@@H]1[C@@H](O)[C@@H](O[C@H]1CO[P@](O)(=O)OP(O)(O)=O)N1C=CC(=O)NC1=O
B4GALT1	DB00141	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1	approved; nutraceutical	N-Acetyl-D-glucosamine	CC(=O)N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O
B4GALT1	DB02696	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1	experimental	6-Aminohexyl-Uridine-C1,5'-Diphosphate	NCCCCCCO[P@](O)(=O)O[P@@](O)(=O)OC[C@@H]1O[C@H]([C@H](O)[C@H]1O)N1C=CC(=O)NC1=O
B4GALT1	DB03013	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1	experimental	Di(N-Acetyl-D-Glucosamine)	CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@H](O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2NC(C)=O)[C@@H]1O
B4GALT1	DB03501	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1	experimental	Uridine Diphosphate Galactose	OC[C@@H]1O[C@H](O[P@](O)(=O)O[P@@](O)(=O)OC[C@@H]2O[C@H]([C@H](O)[C@H]2O)N2C=CC(=O)NC2=O)[C@@H](O)[C@H](O)[C@H]1O
B4GALT1	DB03685	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1	experimental	Uridine-5'-Monophosphate	O[C@@H]1[C@@H](O)[C@@H](O[C@H]1COP(O)(O)=O)N1C=CC(=O)NC1=O
B4GALT1	DB03814	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1	experimental	2-(N-Morpholino)-Ethanesulfonic Acid	[O-]S(=O)(=O)CC[NH+]1CCOCC1
B4GALT2	DB00141	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2	approved; nutraceutical	N-Acetyl-D-glucosamine	CC(=O)N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O
B4GALT3	DB00141	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3	approved; nutraceutical	N-Acetyl-D-glucosamine	CC(=O)N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O
B4GALT4	DB00141	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4	approved; nutraceutical	N-Acetyl-D-glucosamine	CC(=O)N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O
BAAT	DB00145	bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)	approved; nutraceutical	Glycine	NCC(O)=O
BBOX1	DB00126	butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1	approved; nutraceutical	Vitamin C	OC[C@H](O)[C@H]1OC(=O)C(O)=C1O
BBOX1	DB00139	butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1	approved; nutraceutical	Succinic acid	OC(=O)CCC(O)=O
BBOX1	DB00145	butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1	approved; nutraceutical	Glycine	NCC(O)=O
BCAT1	DB00114	branched chain amino-acid transaminase 1, cytosolic	nutraceutical	Pyridoxal Phosphate	CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O
BCAT1	DB00142	branched chain amino-acid transaminase 1, cytosolic	approved; nutraceutical	L-Glutamic Acid	N[C@@H](CCC(O)=O)C(O)=O
BCAT1	DB00149	branched chain amino-acid transaminase 1, cytosolic	approved; nutraceutical	L-Leucine	CC(C)CC(N)C(O)=O
BCAT1	DB00161	branched chain amino-acid transaminase 1, cytosolic	approved; nutraceutical	L-Valine	CC(C)[C@H](N)C(O)=O
BCAT1	DB00167	branched chain amino-acid transaminase 1, cytosolic	approved; nutraceutical	L-Isoleucine	CC[C@H](C)[C@H](N)C(O)=O
BCAT1	DB07544	branched chain amino-acid transaminase 1, cytosolic	experimental	N'-(5-CHLOROBENZOFURAN-2-CARBONYL)-2-(TRIFLUOROMETHYL)BENZENESULFONOHYDRAZIDE	FC(F)(F)C1=CC=CC=C1S(=O)(=O)NNC(=O)C1=CC2=CC(Cl)=CC=C2O1
BCAT1	DB00121	branched chain amino-acid transaminase 1, cytosolic	approved; nutraceutical	Biotin	OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12
BCAT1	DB00130	branched chain amino-acid transaminase 1, cytosolic	approved; nutraceutical; investigational	L-Glutamine	N[C@@H](CCC(N)=O)C(O)=O
BCAT2	DB00114	branched chain amino-acid transaminase 2, mitochondrial	nutraceutical	Pyridoxal Phosphate	CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O
BCAT2	DB00142	branched chain amino-acid transaminase 2, mitochondrial	approved; nutraceutical	L-Glutamic Acid	N[C@@H](CCC(O)=O)C(O)=O
BCAT2	DB00149	branched chain amino-acid transaminase 2, mitochondrial	approved; nutraceutical	L-Leucine	CC(C)CC(N)C(O)=O
BCAT2	DB00167	branched chain amino-acid transaminase 2, mitochondrial	approved; nutraceutical	L-Isoleucine	CC[C@H](C)[C@H](N)C(O)=O
BCAT2	DB02142	branched chain amino-acid transaminase 2, mitochondrial	experimental	Pyridoxamine-5'-Phosphate	CC1=NC=C(COP(O)(O)=O)C(CN)=C1O
BCAT2	DB02635	branched chain amino-acid transaminase 2, mitochondrial	experimental	N-[O-Phosphono-Pyridoxyl]-Isoleucine	CC[C@@H](C)[C@H](NCC1=C(O)C(C)=NC=C1COP(O)(O)=O)C(O)=O
BCAT2	DB04074	branched chain amino-acid transaminase 2, mitochondrial	experimental	Alpha-ketoisovalerate	CC(C)C(=O)C(O)=O
BCAT2	DB00121	branched chain amino-acid transaminase 2, mitochondrial	approved; nutraceutical	Biotin	OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12
BCAT2	DB00161	branched chain amino-acid transaminase 2, mitochondrial	approved; nutraceutical	L-Valine	CC(C)[C@H](N)C(O)=O
BCAT2	DB00130	branched chain amino-acid transaminase 2, mitochondrial	approved; nutraceutical; investigational	L-Glutamine	N[C@@H](CCC(N)=O)C(O)=O
BDH1	DB00157	3-hydroxybutyrate dehydrogenase, type 1	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
BHMT	DB00134	betaine--homocysteine S-methyltransferase	approved; nutraceutical	L-Methionine	CSCC[C@H](N)C(O)=O
BHMT	DB02337	betaine--homocysteine S-methyltransferase	experimental	S-(D-Carboxybutyl)-L-Homocysteine	N[C@@H](CCSCCCCC(O)=O)C(O)=O
BHMT	DB04272	betaine--homocysteine S-methyltransferase	experimental	Citric Acid	OC(=O)CC(O)(CC(O)=O)C(O)=O
BHMT	DB00158	betaine--homocysteine S-methyltransferase	approved; nutraceutical	Folic Acid	NC1=NC(=O)C2=NC(CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)=CN=C2N1
BLVRA	DB00157	biliverdin reductase A	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
BLVRA	DB01907	biliverdin reductase A	experimental	Nicotinamide-Adenine-Dinucleotide	NC(=O)C1=CC=C[N+](=C1)[C@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@@H]1O
BLVRB	DB00140	biliverdin reductase B (flavin reductase (NADPH))	approved; nutraceutical	Riboflavin	CC1=C(C)C=C2N(C[C@H](O)[C@H](O)[C@H](O)CO)C3=NC(=O)NC(=O)C3=NC2=C1
BLVRB	DB00157	biliverdin reductase B (flavin reductase (NADPH))	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
BLVRB	DB02073	biliverdin reductase B (flavin reductase (NADPH))	experimental	Biliverdine Ix Alpha	CC1=C(C=C)\C(NC1=O)=C\C1=N\C(=C/c2nc(\C=C3\NC(=O)C(C=C)=C3C)c(C)c2CCC(O)=O)\C(CCC(O)=O)=C1C
BLVRB	DB03247	biliverdin reductase B (flavin reductase (NADPH))	experimental	Riboflavin Monophosphate	CC1=CC2=C(C=C1C)N(C[C@@H](O)[C@@H](O)[C@H](O)COP(O)(O)=O)C1=NC(=O)NC(=O)C1=N2
BLVRB	DB03461	biliverdin reductase B (flavin reductase (NADPH))	experimental	2'-Monophosphoadenosine 5'-Diphosphoribose	NC(=O)C1=CC=C[N+](=C1)[C@@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@@H]2O[C@H]([C@H](OP(O)(O)=O)[C@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@H]1O
BLVRB	DB04345	biliverdin reductase B (flavin reductase (NADPH))	experimental	7,8-dimethylalloxazine	CC1=CC2=NC3=C(N=C2C=C1C)C(=O)NC(=O)N3
BLVRB	DB04363	biliverdin reductase B (flavin reductase (NADPH))	experimental	Mesobiliverdin Iv Alpha	CCC1=C(C)C(=O)N\C1=C\C1=N\C(=C/c2nc(\C=C3/NC(=O)C(C)=C3CC)c(CCC(O)=O)c2C)\C(C)=C1CCC(O)=O
BLVRB	DB00987	biliverdin reductase B (flavin reductase (NADPH))	approved; investigational	Cytarabine	NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O
BMP1	DB01033	bone morphogenetic protein 1	approved	Mercaptopurine	S=C1N=CNC2=C1NC=N2
BMP1	DB00563	bone morphogenetic protein 1	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
BST1	DB01660	bone marrow stromal cell antigen 1	experimental	Adenosine-5'-Diphosphate Monothiophosphate	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](CO[P@](O)(=O)O[P@@](O)(=O)OP(O)(O)=S)[C@H](O)[C@H]1O
BST1	DB02483	bone marrow stromal cell antigen 1	experimental	Etheno-Nad	O[C@H]1O[C@H](CO[P@](O)(=O)O[P@@](O)(=O)OC[C@@H]2O[C@H]([C@H](O)[C@H]2O)N2C=NC3=C2N=CN2C=CN=C32)[C@@H](O)[C@@H]1O
BST1	DB02701	bone marrow stromal cell antigen 1	experimental	Nicotinamide	NC(=O)C1=CC=CN=C1
BST1	DB03227	bone marrow stromal cell antigen 1	experimental	Nicotinamide Mononucleotide	NC(=O)C1=CC=C[N+](=C1)[C@@H]1O[C@@H](COP(O)(O)=O)[C@H](O)[C@H]1O
BST1	DB03732	bone marrow stromal cell antigen 1	experimental	Etheno-Nadp	O[C@H]1O[C@H](CO[P@](O)(=O)O[P@@](O)(=O)OC[C@@H]2O[C@H]([C@H](OP(O)(O)=O)[C@H]2O)N2C=NC3=C2N=CN2C=CN=C32)[C@@H](O)[C@@H]1O
CA1	DB00232	carbonic anhydrase I	approved	Methyclothiazide	CN1C(CCl)NC2=CC(Cl)=C(C=C2S1(=O)=O)S(N)(=O)=O
CA1	DB00311	carbonic anhydrase I	approved	Ethoxzolamide	CCOC1=CC2=C(C=C1)N=C(S2)S(N)(=O)=O
CA1	DB00381	carbonic anhydrase I	approved	Amlodipine	CCOC(=O)C1=C(COCCN)NC(C)=C(C1C1=CC=CC=C1Cl)C(=O)OC
CA1	DB00423	carbonic anhydrase I	approved	Methocarbamol	COC1=CC=CC=C1OCC(O)COC(N)=O
CA1	DB00436	carbonic anhydrase I	approved	Bendroflumethiazide	NS(=O)(=O)C1=CC2=C(NC(CC3=CC=CC=C3)NS2(=O)=O)C=C1C(F)(F)F
CA1	DB00562	carbonic anhydrase I	approved	Benzthiazide	NS(=O)(=O)C1=C(Cl)C=C2NC(CSCC3=CC=CC=C3)=NS(=O)(=O)C2=C1
CA1	DB00606	carbonic anhydrase I	approved	Cyclothiazide	NS(=O)(=O)C1=C(Cl)C=C2NC(NS(=O)(=O)C2=C1)C1CC2CC1C=C2
CA1	DB00703	carbonic anhydrase I	approved	Methazolamide	CN1N=C(S\C1=N/C(C)=O)S(N)(=O)=O
CA1	DB00774	carbonic anhydrase I	approved	Hydroflumethiazide	NS(=O)(=O)C1=CC2=C(NCNS2(=O)=O)C=C1C(F)(F)F
CA1	DB00819	carbonic anhydrase I	approved	Acetazolamide	CC(=O)NC1=NN=C(S1)S(N)(=O)=O
CA1	DB00869	carbonic anhydrase I	approved	Dorzolamide	CCNC1CC(C)S(=O)(=O)C2=C1C=C(S2)S(N)(=O)=O
CA1	DB00880	carbonic anhydrase I	approved	Chlorothiazide	NS(=O)(=O)C1=C(Cl)C=C2NC=NS(=O)(=O)C2=C1
CA1	DB00909	carbonic anhydrase I	approved; investigational	Zonisamide	NS(=O)(=O)CC1=NOC2=CC=CC=C12
CA1	DB00999	carbonic anhydrase I	approved	Hydrochlorothiazide	NS(=O)(=O)C1=C(Cl)C=C2NCNS(=O)(=O)C2=C1
CA1	DB01021	carbonic anhydrase I	approved	Trichlormethiazide	NS(=O)(=O)C1=C(Cl)C=C2NC(NS(=O)(=O)C2=C1)C(Cl)Cl
CA1	DB01031	carbonic anhydrase I	illicit; approved	Ethinamate	NC(=O)OC1(CCCCC1)C#C
CA1	DB01119	carbonic anhydrase I	approved	Diazoxide	CC1=NS(=O)(=O)C2=C(N1)C=CC(Cl)=C2
CA1	DB01144	carbonic anhydrase I	approved	Dichlorphenamide	NS(=O)(=O)C1=CC(=C(Cl)C(Cl)=C1)S(N)(=O)=O
CA1	DB01194	carbonic anhydrase I	approved	Brinzolamide	CCN[C@H]1CN(CCCOC)S(=O)(=O)C2=C1C=C(S2)S(N)(=O)=O
CA1	DB01325	carbonic anhydrase I	approved	Quinethazone	CCC1NC(=O)C2=CC(=C(Cl)C=C2N1)S(N)(=O)=O
CA1	DB08155	carbonic anhydrase I	experimental	N-{2-[4-(AMINOSULFONYL)PHENYL]ETHYL}ACETAMIDE	CC(=O)NCCC1=CC=C(C=C1)S(N)(=O)=O
CA1	DB08156	carbonic anhydrase I	experimental	3-[4-(AMINOSULFONYL)PHENYL]PROPANOIC ACID	NS(=O)(=O)C1=CC=C(CCC(O)=O)C=C1
CA1	DB08157	carbonic anhydrase I	experimental	ETHYL 3-[4-(AMINOSULFONYL)PHENYL]PROPANOATE	CCOC(=O)CCC1=CC=C(C=C1)S(N)(=O)=O
CA12	DB00562	carbonic anhydrase XII	approved	Benzthiazide	NS(=O)(=O)C1=C(Cl)C=C2NC(CSCC3=CC=CC=C3)=NS(=O)(=O)C2=C1
CA12	DB00774	carbonic anhydrase XII	approved	Hydroflumethiazide	NS(=O)(=O)C1=CC2=C(NCNS2(=O)=O)C=C1C(F)(F)F
CA12	DB00909	carbonic anhydrase XII	approved; investigational	Zonisamide	NS(=O)(=O)CC1=NOC2=CC=CC=C12
CA12	DB00999	carbonic anhydrase XII	approved	Hydrochlorothiazide	NS(=O)(=O)C1=C(Cl)C=C2NCNS(=O)(=O)C2=C1
CA13	DB00909	carbonic anhydrase XIII	approved; investigational	Zonisamide	NS(=O)(=O)CC1=NOC2=CC=CC=C12
CA13	DB07115	carbonic anhydrase XIII	experimental	N-(4-chlorobenzyl)-N-methylbenzene-1,4-disulfonamide	CN(CC1=CC=C(Cl)C=C1)S(=O)(=O)C1=CC=C(C=C1)S(N)(=O)=O
CA14	DB00819	carbonic anhydrase XIV	approved	Acetazolamide	CC(=O)NC1=NN=C(S1)S(N)(=O)=O
CA14	DB00909	carbonic anhydrase XIV	approved; investigational	Zonisamide	NS(=O)(=O)CC1=NOC2=CC=CC=C12
CA14	DB02687	carbonic anhydrase XIV	experimental	Beta-D-Mannose	OC[C@@H]1O[C@H](O)[C@@H](O)[C@H](O)[C@H]1O
CA2	DB00232	carbonic anhydrase II	approved	Methyclothiazide	CN1C(CCl)NC2=CC(Cl)=C(C=C2S1(=O)=O)S(N)(=O)=O
CA2	DB00273	carbonic anhydrase II	approved; investigational	Topiramate	CC1(C)O[C@@H]2CO[C@@]3(COS(N)(=O)=O)OC(C)(C)O[C@H]3[C@@H]2O1
CA2	DB00311	carbonic anhydrase II	approved	Ethoxzolamide	CCOC1=CC2=C(C=C1)N=C(S2)S(N)(=O)=O
CA2	DB00436	carbonic anhydrase II	approved	Bendroflumethiazide	NS(=O)(=O)C1=CC2=C(NC(CC3=CC=CC=C3)NS2(=O)=O)C=C1C(F)(F)F
CA2	DB00562	carbonic anhydrase II	approved	Benzthiazide	NS(=O)(=O)C1=C(Cl)C=C2NC(CSCC3=CC=CC=C3)=NS(=O)(=O)C2=C1
CA2	DB00606	carbonic anhydrase II	approved	Cyclothiazide	NS(=O)(=O)C1=C(Cl)C=C2NC(NS(=O)(=O)C2=C1)C1CC2CC1C=C2
CA2	DB00695	carbonic anhydrase II	approved	Furosemide	NS(=O)(=O)C1=C(Cl)C=C(NCC2=CC=CO2)C(=C1)C(O)=O
CA2	DB00703	carbonic anhydrase II	approved	Methazolamide	CN1N=C(S\C1=N/C(C)=O)S(N)(=O)=O
CA2	DB00774	carbonic anhydrase II	approved	Hydroflumethiazide	NS(=O)(=O)C1=CC2=C(NCNS2(=O)=O)C=C1C(F)(F)F
CA2	DB00819	carbonic anhydrase II	approved	Acetazolamide	CC(=O)NC1=NN=C(S1)S(N)(=O)=O
CA2	DB00869	carbonic anhydrase II	approved	Dorzolamide	CCNC1CC(C)S(=O)(=O)C2=C1C=C(S2)S(N)(=O)=O
CA2	DB00880	carbonic anhydrase II	approved	Chlorothiazide	NS(=O)(=O)C1=C(Cl)C=C2NC=NS(=O)(=O)C2=C1
CA2	DB00909	carbonic anhydrase II	approved; investigational	Zonisamide	NS(=O)(=O)CC1=NOC2=CC=CC=C12
CA2	DB00999	carbonic anhydrase II	approved	Hydrochlorothiazide	NS(=O)(=O)C1=C(Cl)C=C2NCNS(=O)(=O)C2=C1
CA2	DB01021	carbonic anhydrase II	approved	Trichlormethiazide	NS(=O)(=O)C1=C(Cl)C=C2NC(NS(=O)(=O)C2=C1)C(Cl)Cl
CA2	DB01031	carbonic anhydrase II	illicit; approved	Ethinamate	NC(=O)OC1(CCCCC1)C#C
CA2	DB01119	carbonic anhydrase II	approved	Diazoxide	CC1=NS(=O)(=O)C2=C(N1)C=CC(Cl)=C2
CA2	DB01144	carbonic anhydrase II	approved	Dichlorphenamide	NS(=O)(=O)C1=CC(=C(Cl)C(Cl)=C1)S(N)(=O)=O
CA2	DB01194	carbonic anhydrase II	approved	Brinzolamide	CCN[C@H]1CN(CCCOC)S(=O)(=O)C2=C1C=C(S2)S(N)(=O)=O
CA2	DB01325	carbonic anhydrase II	approved	Quinethazone	CCC1NC(=O)C2=CC(=C(Cl)C=C2N1)S(N)(=O)=O
CA2	DB01671	carbonic anhydrase II	experimental	4-(Hydroxymercury)Benzoic Acid	O[Hg]C1=CC=C(C=C1)C(O)=O
CA2	DB01748	carbonic anhydrase II	experimental	N-Benzyl-4-Sulfamoyl-Benzamide	NS(=O)(=O)C1=CC=C(C=C1)C(=O)NCC1=CC=CC=C1
CA2	DB01784	carbonic anhydrase II	experimental	4-Flourobenzenesulfonamide	NS(=O)(=O)C1=CC=C(F)C=C1
CA2	DB01942	carbonic anhydrase II	experimental	Formic Acid	OC=O
CA2	DB01964	carbonic anhydrase II	experimental	AL5424	COC1=CC=C(C=C1)N1C[C@H](O)C2=C(SC(=C2)S(N)(=O)=O)S1(=O)=O
CA2	DB02069	carbonic anhydrase II	experimental	N-(2-Flouro-Benzyl)-4-Sulfamoyl-Benzamide	NS(=O)(=O)C1=CC=C(C=C1)C(=O)NCC1=CC=CC=C1F
CA2	DB02087	carbonic anhydrase II	experimental	3,5-Difluorobenzenesulfonamide	NS(=O)(=O)C1=CC(F)=CC(F)=C1
CA2	DB02220	carbonic anhydrase II	experimental	Al7089a	CN[C@H]1CN(C2=CC=CC(OC)=C2)S(=O)(=O)C2=C1C=C(S2)S(N)(=O)=O
CA2	DB02221	carbonic anhydrase II	experimental	4-(Aminosulfonyl)-N-[(2,4,6-Trifluorophenyl)Methyl]-Benzamide	NS(=O)(=O)C1=CC=C(C=C1)C(=O)NCC1=C(F)C=C(F)C=C1F
CA2	DB02292	carbonic anhydrase II	experimental	6-Oxo-8,9,10,11-Tetrahydro-7h-Cyclohepta[C][1]Benzopyran-3-O-Sulfamate	NS(=O)(=O)OC1=CC=C2C3=C(CCCCC3)C(=O)OC2=C1
CA2	DB02429	carbonic anhydrase II	experimental	4-(Aminosulfonyl)-N-[(4-Fluorophenyl)Methyl]-Benzamide	NS(=O)(=O)C1=CC=C(C=C1)C(=O)NCC1=CC=C(F)C=C1
CA2	DB02479	carbonic anhydrase II	experimental	(R)-N-(3-Indol-1-Yl-2-Methyl-Propyl)-4-Sulfamoyl-Benzamide	C[C@H](CNC(=O)C1=CC=C(C=C1)S(N)(=O)=O)CN1C=CC2=CC=CC=C12
CA2	DB02535	carbonic anhydrase II	experimental	Aminodi(Ethyloxy)Ethylaminocarbonylbenzenesulfonamide	NCCOCCOCCNC(=O)C1=CC=C(C=C1)S(N)(=O)=O
CA2	DB02602	carbonic anhydrase II	experimental	AL7182	COC1=CC(=CC=C1)N1CCC2=C(SC(=C2)S(N)(=O)=O)S1(=O)=O
CA2	DB02610	carbonic anhydrase II	experimental	N-(2,3,4,5,6-Pentaflouro-Benzyl)-4-Sulfamoyl-Benzamide	NS(=O)(=O)C1=CC=C(C=C1)C(=O)NCC1=C(F)C(F)=C(F)C(F)=C1F
CA2	DB02679	carbonic anhydrase II	experimental	Cyanamide	NC#N
CA2	DB02861	carbonic anhydrase II	experimental	4-(Aminosulfonyl)-N-[(3,4,5-Trifluorophenyl)Methyl]-Benzamide	NS(=O)(=O)C1=CC=C(C=C1)C(=O)NCC1=CC(F)=C(F)C(F)=C1
CA2	DB02866	carbonic anhydrase II	experimental	Dansylamide	CN(C)C1=C2C=CC=C(C2=CC=C1)S(N)(=O)=O
CA2	DB02894	carbonic anhydrase II	experimental	Sulfamic Acid 2,3-O-(1-Methylethylidene)-4,5-O-Sulfonyl-Beta-Fructopyranose Ester	CC1(C)O[C@H]2[C@H]3OS(=O)(=O)O[C@H]3CO[C@@]2(COS(N)(=O)=O)O1
CA2	DB02986	carbonic anhydrase II	experimental	N-(2-Thienylmethyl)-2,5-Thiophenedisulfonamide	NS(=O)(=O)C1=CC=C(S1)S(=O)(=O)NCC1=CC=CS1
CA2	DB03039	carbonic anhydrase II	experimental	4-(Aminosulfonyl)-N-[(2,5-Difluorophenyl)Methyl]-Benzamide	NS(=O)(=O)C1=CC=C(C=C1)C(=O)NCC1=CC(F)=CC=C1F
CA2	DB03221	carbonic anhydrase II	experimental	AL7099A	CN[C@@H]1CN(C2=CC=CC(OC)=C2)S(=O)(=O)C2=C1C=C(S2)S(N)(=O)=O
CA2	DB03262	carbonic anhydrase II	experimental	Al-6619, [2h-Thieno[3,2-E]-1,2-Thiazine-6-Sulfonamide,2-(3-Hydroxyphenyl)-3-(4-Morpholinyl)-, 1,1-Dioxide]	NS(=O)(=O)C1=CC2=C(S1)S(=O)(=O)N(C(CN1CCOCC1)=C2)C1=CC(O)=CC=C1
CA2	DB03270	carbonic anhydrase II	experimental	2,6-Difluorobenzenesulfonamide	NS(=O)(=O)C1=C(F)C=CC=C1F
CA2	DB03294	carbonic anhydrase II	experimental	1-Methyl-3-Oxo-1,3-Dihydro-Benzo[C]Isothiazole-5-Sulfonic Acid Amide	CN1SC(=O)C2=CC(=CC=C12)S(N)(=O)=O
CA2	DB03333	carbonic anhydrase II	experimental	(4-sulfamoyl-phenyl)-thiocarbamic acid O-(2-thiophen-3-yl-ethyl) ester	NS(=O)(=O)C1=CC=C(NC(=S)OCCC2=CSC=C2)C=C1
CA2	DB03385	carbonic anhydrase II	experimental	4-Methylimidazole	Cc1cncn1
CA2	DB03526	carbonic anhydrase II	experimental	AL5927	COC1=CC=C(CNS(=O)(=O)C2=CC=C(S2)S(N)(=O)=O)C=C1
CA2	DB03594	carbonic anhydrase II	experimental	1,2,4-Triazole	c1ncnn1
CA2	DB03596	carbonic anhydrase II	experimental	N-[2-(1h-Indol-5-Yl)-Butyl]-4-Sulfamoyl-Benzamide	CC[C@H](CNC(=O)C1=CC=C(C=C1)S(N)(=O)=O)C1=CC2=C(NC=C2)C=C1
CA2	DB03598	carbonic anhydrase II	experimental	Al-6629, [2h-Thieno[3,2-E]-1,2-Thiazine-6-Sulfonamide,2-(3-Methoxyphenyl)-3-(4-Morpholinyl)-, 1,1-Dioxide]	COC1=CC=CC(=C1)N1C(CN2CCOCC2)=CC2=C(SC(=C2)S(N)(=O)=O)S1(=O)=O
CA2	DB03674	carbonic anhydrase II	experimental	Methyl Mercury Ion	C[Hg+]
CA2	DB03697	carbonic anhydrase II	experimental	4-Sulfonamide-[1-(4-Aminobutane)]Benzamide	NCCCCNC(=O)C1=CC=C(C=C1)S(N)(=O)=O
CA2	DB03844	carbonic anhydrase II	experimental	N-(2,6-Diflouro-Benzyl)-4-Sulfamoyl-Benzamide	NS(=O)(=O)C1=CC=C(C=C1)C(=O)NCC1=C(F)C=CC=C1F
CA2	DB03877	carbonic anhydrase II	experimental	AL4623	CCN[C@@H]1CN(CCOC)S(=O)(=O)C2=C1C=C(S2)S(N)(=O)=O
CA2	DB03904	carbonic anhydrase II	experimental	Urea	NC(N)=O
CA2	DB03950	carbonic anhydrase II	experimental	(S)-N-(3-Indol-1-Yl-2-Methyl-Propyl)-4-Sulfamoyl-Benzamide	C[C@@H](CNC(=O)C1=CC=C(C=C1)S(N)(=O)=O)CN1C=CC2=CC=CC=C12
CA2	DB03975	carbonic anhydrase II	experimental	Mercuribenzoic Acid	OC(=O)C1=CC=C([Hg])C=C1
CA2	DB04002	carbonic anhydrase II	experimental	4-Sulfonamide-[4-(Thiomethylaminobutane)]Benzamide	NS(=O)(=O)C1=CC=C(C=C1)C(=O)NCCCCNCS
CA2	DB04081	carbonic anhydrase II	experimental	(4s-Trans)-4-(Methylamino)-5,6-Dihydro-6-Methyl-4h-Thieno(2,3-B)Thiopyran-2-Sulfonamide-7,7-Dioxide	CN[C@@H]1C[C@H](C)S(=O)(=O)C2=C1C=C(S2)S(N)(=O)=O
CA2	DB04089	carbonic anhydrase II	experimental	AL5300	NS(=O)(=O)C1=CC2=C(S1)S(=O)(=O)N(CC1=CC=CS1)C[C@@H]2O
CA2	DB04180	carbonic anhydrase II	experimental	4-(Aminosulfonyl)-N-[(2,4-Difluorophenyl)Methyl]-Benzamide	NS(=O)(=O)C1=CC=C(C=C1)C(=O)NCC1=C(F)C=C(F)C=C1
CA2	DB04203	carbonic anhydrase II	experimental	3-Mercuri-4-Aminobenzenesulfonamide	NC1=CC=C(C=C1[Hg])S(N)(=O)=O
CA2	DB04371	carbonic anhydrase II	experimental	AL6528	COC1=CC(=CC=C1)N1C=CC2=C(SC(=C2)S(N)(=O)=O)S1(=O)=O
CA2	DB04394	carbonic anhydrase II	experimental	3-Nitro-4-(2-Oxo-Pyrrolidin-1-Yl)-Benzenesulfonamide	NS(=O)(=O)C1=CC=C(N2CCCC2=O)C(=C1)[N+]([O-])=O
CA2	DB04549	carbonic anhydrase II	experimental	4-(Aminosulfonyl)-N-[(2,3,4-Trifluorophenyl)Methyl]-Benzamide	NS(=O)(=O)C1=CC=C(C=C1)C(=O)NCC1=C(F)C(F)=C(F)C=C1
CA2	DB04600	carbonic anhydrase II	experimental	4-[(3-BROMO-4-O-SULFAMOYLBENZYL)(4-CYANOPHENYL)AMINO]-4H-[1,2,4]-TRIAZOLE	NS(=O)(=O)OC1=CC=C(CN(N2C=NN=C2)C2=CC=C(C=C2)C#N)C=C1Br
CA2	DB04601	carbonic anhydrase II	experimental	4-[(4-O-SULFAMOYLBENZYL)(4-CYANOPHENYL)AMINO]-4H-[1,2,4]-TRIAZOLE	NS(=O)(=O)OC1=CC=C(CN(N2C=NN=C2)C2=CC=C(C=C2)C#N)C=C1
CA2	DB04763	carbonic anhydrase II	experimental	1-N-(4-SULFAMOYLPHENYL-ETHYL)-2,4,6-TRIMETHYLPYRIDINIUM	CC1=CC(C)=[N+](CCC2=CC=C(C=C2)S(N)(=O)=O)C(C)=C1
CA2	DB06891	carbonic anhydrase II	experimental	5-{[(4-AMINO-3-CHLORO-5-FLUOROPHENYL)SULFONYL]AMINO}-1,3,4-THIADIAZOLE-2-SULFONAMIDE	NC1=C(F)C=C(C=C1Cl)S(=O)(=O)NC1=NN=C(S1)S(N)(=O)=O
CA2	DB06954	carbonic anhydrase II	experimental	2-(cycloheptylmethyl)-1,1-dioxido-1-benzothiophen-6-yl sulfamate	NS(=O)(=O)OC1=CC=C2C=C(CC3CCCCCC3)S(=O)(=O)C2=C1
CA2	DB07048	carbonic anhydrase II	experimental	N-[(2R)-5-(aminosulfonyl)-2,3-dihydro-1H-inden-2-yl]-2-propylpentanamide	CCCC(CCC)C(=O)N[C@@H]1CC2=C(C1)C=C(C=C2)S(N)(=O)=O
CA2	DB07050	carbonic anhydrase II	experimental	5-[(phenylsulfonyl)amino]-1,3,4-thiadiazole-2-sulfonamide	NS(=O)(=O)C1=NN=C(NS(=O)(=O)C2=CC=CC=C2)S1
CA2	DB07363	carbonic anhydrase II	experimental	THIOPHENE-2,5-DISULFONIC ACID 2-AMIDE-5-(4-METHYL-BENZYLAMIDE)	CC1=CC=C(CNS(=O)(=O)C2=CC=C(S2)S(N)(=O)=O)C=C1
CA2	DB07467	carbonic anhydrase II	experimental	4-chloro-N-[(2S)-2-methyl-2,3-dihydro-1H-indol-1-yl]-3-sulfamoylbenzamide	C[C@H]1CC2=CC=CC=C2N1NC(=O)C1=CC=C(Cl)C(=C1)S(N)(=O)=O
CA2	DB07476	carbonic anhydrase II	experimental	N-[4-(AMINOSULFONYL)PHENYL]-2-MERCAPTOBENZAMIDE	NS(=O)(=O)C1=CC=C(NC(=O)C2=CC=CC=C2S)C=C1
CA2	DB07596	carbonic anhydrase II	experimental	(17beta)-17-(cyanomethyl)-2-methoxyestra-1(10),2,4-trien-3-yl sulfamate	COC1=C(OS(N)(=O)=O)C=C2CC[C@H]3[C@@H]4CC[C@H](CC#N)[C@@]4(C)CC[C@@H]3C2=C1
CA2	DB07632	carbonic anhydrase II	experimental	5-(2-chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide	NS(=O)(=O)C1=NN=C(S1)C1=CC=CC=C1Cl
CA2	DB07710	carbonic anhydrase II	experimental	PHENYLALANYLAMINODI(ETHYLOXY)ETHYL BENZENESULFONAMIDEAMINOCARBONYLBENZENESULFONAMIDE	N[C@@H](CC1=CC=CC=C1)C(=O)NCCOCCOCCNC(=O)C1=CC=C(C=C1)S(N)(=O)=O
CA2	DB07742	carbonic anhydrase II	experimental	N-(2,3-DIFLUORO-BENZYL)-4-SULFAMOYL-BENZAMIDE	NS(=O)(=O)C1=CC=C(C=C1)C(=O)NCC1=CC=CC(F)=C1F
CA2	DB08046	carbonic anhydrase II	experimental	2-chloro-5-[(1S)-1-hydroxy-3-oxo-2H-isoindol-1-yl]benzenesulfonamide	NS(=O)(=O)C1=CC(=CC=C1Cl)[C@@]1(O)NC(=O)C2=CC=CC=C12
CA2	DB08083	carbonic anhydrase II	experimental	2-(1,3-thiazol-4-yl)-1H-benzimidazole-5-sulfonamide	NS(=O)(=O)C1=CC=C2NC(=NC2=C1)C1=CSC=N1
CA2	DB08155	carbonic anhydrase II	experimental	N-{2-[4-(AMINOSULFONYL)PHENYL]ETHYL}ACETAMIDE	CC(=O)NCCC1=CC=C(C=C1)S(N)(=O)=O
CA2	DB08156	carbonic anhydrase II	experimental	3-[4-(AMINOSULFONYL)PHENYL]PROPANOIC ACID	NS(=O)(=O)C1=CC=C(CCC(O)=O)C=C1
CA2	DB08157	carbonic anhydrase II	experimental	ETHYL 3-[4-(AMINOSULFONYL)PHENYL]PROPANOATE	CCOC(=O)CCC1=CC=C(C=C1)S(N)(=O)=O
CA2	DB08165	carbonic anhydrase II	experimental	indane-5-sulfonamide	NS(=O)(=O)C1=CC=C2CCCC2=C1
CA2	DB08202	carbonic anhydrase II	experimental	4-({[(4-METHYLPIPERAZIN-1-YL)AMINO]CARBONOTHIOYL}AMINO)BENZENESULFONAMIDE	CN1CCN(CC1)NC(=S)NC1=CC=C(C=C1)S(N)(=O)=O
CA2	DB08301	carbonic anhydrase II	experimental	N-({[4-(AMINOSULFONYL)PHENYL]AMINO}CARBONYL)-4-METHYLBENZENESULFONAMIDE	CC1=CC=C(C=C1)S(=O)(=O)NC(=O)NC1=CC=C(C=C1)S(N)(=O)=O
CA2	DB08329	carbonic anhydrase II	experimental	SULTHIAME	NS(=O)(=O)C1=CC=C(C=C1)N1CCCCS1(=O)=O
CA2	DB08416	carbonic anhydrase II	experimental	(9BETA,13ALPHA,14BETA,17ALPHA)-2-METHOXYESTRA-1,3,5(10)-TRIENE-3,17-DIYL DISULFAMATE	COC1=CC2=C(CC[C@H]3[C@@H]4CC[C@H](OS(N)(=O)=O)[C@@]4(C)CC[C@H]23)C=C1OS(N)(=O)=O
CA2	DB08418	carbonic anhydrase II	experimental	(4aS,4bR,10bS,12aS)-12a-methyl-1,3-dioxo-2-(pyridin-3-ylmethyl)-1,2,3,4,4a,4b,5,6,10b,11,12,12a-dodecahydronaphtho[2,1-f]isoquinolin-8-yl sulfamate	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(OS(N)(=O)=O)=C4)[C@@H]1CC(=O)N(CC1=CC=CN=C1)C2=O
CA2	DB08645	carbonic anhydrase II	experimental	6-CHLORO-3-(DICHLOROMETHYL)-3,4-DIHYDRO-2H-1,2,4-BENZOTHIADIAZINE-7-SULFONAMIDE 1,1-DIOXIDE	NS(=O)(=O)C1=C(Cl)C=C2N[C@H](NS(=O)(=O)C2=C1)C(Cl)Cl
CA2	DB08659	carbonic anhydrase II	experimental	2-(hydrazinocarbonyl)-3-phenyl-1H-indole-5-sulfonamide	NNC(=O)C1=C(C2=C(N1)C=CC(=C2)S(N)(=O)=O)C1=CC=CC=C1
CA2	DB08765	carbonic anhydrase II	experimental	6-HYDROXY-1,3-BENZOTHIAZOLE-2-SULFONAMIDE	NS(=O)(=O)C1=NC2=C(S1)C=C(O)C=C2
CA2	DB08782	carbonic anhydrase II	experimental	4-(2-AMINOETHYL)BENZENESULFONAMIDE	NCCC1=CC=C(C=C1)S(N)(=O)=O
CA2	DB00259	carbonic anhydrase II	approved	Sulfanilamide	NC1=CC=C(C=C1)S(N)(=O)=O
CA3	DB00819	carbonic anhydrase III, muscle specific	approved	Acetazolamide	CC(=O)NC1=NN=C(S1)S(N)(=O)=O
CA3	DB00909	carbonic anhydrase III, muscle specific	approved; investigational	Zonisamide	NS(=O)(=O)CC1=NOC2=CC=CC=C12
CA3	DB01033	carbonic anhydrase III, muscle specific	approved	Mercaptopurine	S=C1N=CNC2=C1NC=N2
CA3	DB00563	carbonic anhydrase III, muscle specific	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
CA4	DB00232	carbonic anhydrase IV	approved	Methyclothiazide	CN1C(CCl)NC2=CC(Cl)=C(C=C2S1(=O)=O)S(N)(=O)=O
CA4	DB00273	carbonic anhydrase IV	approved; investigational	Topiramate	CC1(C)O[C@@H]2CO[C@@]3(COS(N)(=O)=O)OC(C)(C)O[C@H]3[C@@H]2O1
CA4	DB00311	carbonic anhydrase IV	approved	Ethoxzolamide	CCOC1=CC2=C(C=C1)N=C(S2)S(N)(=O)=O
CA4	DB00436	carbonic anhydrase IV	approved	Bendroflumethiazide	NS(=O)(=O)C1=CC2=C(NC(CC3=CC=CC=C3)NS2(=O)=O)C=C1C(F)(F)F
CA4	DB00562	carbonic anhydrase IV	approved	Benzthiazide	NS(=O)(=O)C1=C(Cl)C=C2NC(CSCC3=CC=CC=C3)=NS(=O)(=O)C2=C1
CA4	DB00606	carbonic anhydrase IV	approved	Cyclothiazide	NS(=O)(=O)C1=C(Cl)C=C2NC(NS(=O)(=O)C2=C1)C1CC2CC1C=C2
CA4	DB00703	carbonic anhydrase IV	approved	Methazolamide	CN1N=C(S\C1=N/C(C)=O)S(N)(=O)=O
CA4	DB00774	carbonic anhydrase IV	approved	Hydroflumethiazide	NS(=O)(=O)C1=CC2=C(NCNS2(=O)=O)C=C1C(F)(F)F
CA4	DB00819	carbonic anhydrase IV	approved	Acetazolamide	CC(=O)NC1=NN=C(S1)S(N)(=O)=O
CA4	DB00869	carbonic anhydrase IV	approved	Dorzolamide	CCNC1CC(C)S(=O)(=O)C2=C1C=C(S2)S(N)(=O)=O
CA4	DB00880	carbonic anhydrase IV	approved	Chlorothiazide	NS(=O)(=O)C1=C(Cl)C=C2NC=NS(=O)(=O)C2=C1
CA4	DB00909	carbonic anhydrase IV	approved; investigational	Zonisamide	NS(=O)(=O)CC1=NOC2=CC=CC=C12
CA4	DB00999	carbonic anhydrase IV	approved	Hydrochlorothiazide	NS(=O)(=O)C1=C(Cl)C=C2NCNS(=O)(=O)C2=C1
CA4	DB01021	carbonic anhydrase IV	approved	Trichlormethiazide	NS(=O)(=O)C1=C(Cl)C=C2NC(NS(=O)(=O)C2=C1)C(Cl)Cl
CA4	DB01144	carbonic anhydrase IV	approved	Dichlorphenamide	NS(=O)(=O)C1=CC(=C(Cl)C(Cl)=C1)S(N)(=O)=O
CA4	DB01194	carbonic anhydrase IV	approved	Brinzolamide	CCN[C@H]1CN(CCCOC)S(=O)(=O)C2=C1C=C(S2)S(N)(=O)=O
CA5A	DB00909	carbonic anhydrase VA, mitochondrial	approved; investigational	Zonisamide	NS(=O)(=O)CC1=NOC2=CC=CC=C12
CA5A	DB01194	carbonic anhydrase VA, mitochondrial	approved	Brinzolamide	CCN[C@H]1CN(CCCOC)S(=O)(=O)C2=C1C=C(S2)S(N)(=O)=O
CA5A	DB03385	carbonic anhydrase VA, mitochondrial	experimental	4-Methylimidazole	Cc1cncn1
CA5B	DB00909	carbonic anhydrase VB, mitochondrial	approved; investigational	Zonisamide	NS(=O)(=O)CC1=NOC2=CC=CC=C12
CA7	DB00311	carbonic anhydrase VII	approved	Ethoxzolamide	CCOC1=CC2=C(C=C1)N=C(S2)S(N)(=O)=O
CA7	DB00703	carbonic anhydrase VII	approved	Methazolamide	CN1N=C(S\C1=N/C(C)=O)S(N)(=O)=O
CA7	DB00819	carbonic anhydrase VII	approved	Acetazolamide	CC(=O)NC1=NN=C(S1)S(N)(=O)=O
CA7	DB00909	carbonic anhydrase VII	approved; investigational	Zonisamide	NS(=O)(=O)CC1=NOC2=CC=CC=C12
CA7	DB01144	carbonic anhydrase VII	approved	Dichlorphenamide	NS(=O)(=O)C1=CC(=C(Cl)C(Cl)=C1)S(N)(=O)=O
CA8	DB00909	carbonic anhydrase VIII	approved; investigational	Zonisamide	NS(=O)(=O)CC1=NOC2=CC=CC=C12
CA9	DB00562	carbonic anhydrase IX	approved	Benzthiazide	NS(=O)(=O)C1=C(Cl)C=C2NC(CSCC3=CC=CC=C3)=NS(=O)(=O)C2=C1
CA9	DB00774	carbonic anhydrase IX	approved	Hydroflumethiazide	NS(=O)(=O)C1=CC2=C(NCNS2(=O)=O)C=C1C(F)(F)F
CA9	DB00909	carbonic anhydrase IX	approved; investigational	Zonisamide	NS(=O)(=O)CC1=NOC2=CC=CC=C12
CA9	DB00999	carbonic anhydrase IX	approved	Hydrochlorothiazide	NS(=O)(=O)C1=C(Cl)C=C2NCNS(=O)(=O)C2=C1
CACNA1A	DB00230	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	illicit; approved; investigational	Pregabalin	CC(C)C[C@H](CN)CC(O)=O
CACNA1A	DB00661	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	approved	Verapamil	COC1=C(OC)C=C(CCN(C)CCCC(C#N)(C(C)C)C2=CC(OC)=C(OC)C=C2)C=C1
CACNA1A	DB00836	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	approved	Loperamide	CN(C)C(=O)C(CCN1CCC(O)(CC1)C1=CC=C(Cl)C=C1)(C1=CC=CC=C1)C1=CC=CC=C1
CACNA1A	DB01244	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	approved	Bepridil	CC(C)COCC(CN(CC1=CC=CC=C1)C1=CC=CC=C1)N1CCCC1
CACNB2	DB00270	calcium channel, voltage-dependent, beta 2 subunit	approved	Isradipine	COC(=O)C1=C(C)NC(C)=C(C1C1=CC=CC2=NON=C12)C(=O)OC(C)C
CACNB2	DB00381	calcium channel, voltage-dependent, beta 2 subunit	approved	Amlodipine	CCOC(=O)C1=C(COCCN)NC(C)=C(C1C1=CC=CC=C1Cl)C(=O)OC
CACNB2	DB00393	calcium channel, voltage-dependent, beta 2 subunit	approved	Nimodipine	COCCOC(=O)C1=C(C)NC(C)=C(C1C1=CC(=CC=C1)[N+]([O-])=O)C(=O)OC(C)C
CACNB2	DB00401	calcium channel, voltage-dependent, beta 2 subunit	approved	Nisoldipine	COC(=O)C1=C(C)NC(C)=C(C1C1=CC=CC=C1[N+]([O-])=O)C(=O)OCC(C)C
CACNB2	DB00622	calcium channel, voltage-dependent, beta 2 subunit	approved	Nicardipine	COC(=O)C1=C(C)NC(C)=C(C1C1=CC(=CC=C1)[N+]([O-])=O)C(=O)OCCN(C)CC1=CC=CC=C1
CACNB2	DB00653	calcium channel, voltage-dependent, beta 2 subunit	approved	Magnesium Sulfate	[Mg++].[O-]S([O-])(=O)=O
CACNB2	DB00661	calcium channel, voltage-dependent, beta 2 subunit	approved	Verapamil	COC1=C(OC)C=C(CCN(C)CCCC(C#N)(C(C)C)C2=CC(OC)=C(OC)C=C2)C=C1
CACNB2	DB01023	calcium channel, voltage-dependent, beta 2 subunit	approved; investigational	Felodipine	CCOC(=O)C1=C(C)NC(C)=C(C1C1=C(Cl)C(Cl)=CC=C1)C(=O)OC
CACNB2	DB01054	calcium channel, voltage-dependent, beta 2 subunit	approved	Nitrendipine	CCOC(=O)C1=C(C)NC(C)=C(C1C1=CC(=CC=C1)[N+]([O-])=O)C(=O)OC
CACNB2	DB01115	calcium channel, voltage-dependent, beta 2 subunit	approved	Nifedipine	COC(=O)C1=C(C)NC(C)=C(C1C1=CC=CC=C1[N+]([O-])=O)C(=O)OC
CACNB2	DB01388	calcium channel, voltage-dependent, beta 2 subunit	withdrawn	Mibefradil	COCC(=O)O[C@]1(CCN(C)CCCC2=NC3=CC=CC=C3N2)CCC2=C(C=CC(F)=C2)[C@@H]1C(C)C
CACNB2	DB06712	calcium channel, voltage-dependent, beta 2 subunit	approved	Nilvadipine	COC(=O)C1=C(NC(C)=C(C1C1=CC(=CC=C1)[N+]([O-])=O)C(=O)OC(C)C)C#N
CACNB3	DB00393	calcium channel, voltage-dependent, beta 3 subunit	approved	Nimodipine	COCCOC(=O)C1=C(C)NC(C)=C(C1C1=CC(=CC=C1)[N+]([O-])=O)C(=O)OC(C)C
CACNB3	DB00661	calcium channel, voltage-dependent, beta 3 subunit	approved	Verapamil	COC1=C(OC)C=C(CCN(C)CCCC(C#N)(C(C)C)C2=CC(OC)=C(OC)C=C2)C=C1
CACNB3	DB01388	calcium channel, voltage-dependent, beta 3 subunit	withdrawn	Mibefradil	COCC(=O)O[C@]1(CCN(C)CCCC2=NC3=CC=CC=C3N2)CCC2=C(C=CC(F)=C2)[C@@H]1C(C)C
CAD	DB00128	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase	approved; nutraceutical	L-Aspartic Acid	N[C@@H](CC(O)=O)C(O)=O
CAD	DB03459	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase	experimental	N-(Phosphonacetyl)-L-Aspartic Acid	OC(=O)C[C@@H](NC(=O)CP(O)(O)=O)C(O)=O
CAD	DB00130	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase	approved; nutraceutical; investigational	L-Glutamine	N[C@@H](CCC(N)=O)C(O)=O
CALM1	DB00527	calmodulin 1 (phosphorylase kinase, delta)	approved	Dibucaine	CCCCOC1=NC2=CC=CC=C2C(=C1)C(=O)NCCN(CC)CC
CALM1	DB00622	calmodulin 1 (phosphorylase kinase, delta)	approved	Nicardipine	COC(=O)C1=C(C)NC(C)=C(C1C1=CC(=CC=C1)[N+]([O-])=O)C(=O)OCCN(C)CC1=CC=CC=C1
CALM1	DB00623	calmodulin 1 (phosphorylase kinase, delta)	approved	Fluphenazine	OCCN1CCN(CCCN2C3=CC=CC=C3SC3=C2C=C(C=C3)C(F)(F)F)CC1
CALM1	DB00753	calmodulin 1 (phosphorylase kinase, delta)	approved	Isoflurane	FC(F)OC(Cl)C(F)(F)F
CALM1	DB00831	calmodulin 1 (phosphorylase kinase, delta)	approved	Trifluoperazine	CN1CCN(CCCN2C3=CC=CC=C3SC3=C2C=C(C=C3)C(F)(F)F)CC1
CALM1	DB00836	calmodulin 1 (phosphorylase kinase, delta)	approved	Loperamide	CN(C)C(=O)C(CCN1CCC(O)(CC1)C1=CC=C(Cl)C=C1)(C1=CC=CC=C1)C1=CC=CC=C1
CALM1	DB00850	calmodulin 1 (phosphorylase kinase, delta)	approved	Perphenazine	OCCN1CCN(CCCN2C3=CC=CC=C3SC3=C2C=C(Cl)C=C3)CC1
CALM1	DB00925	calmodulin 1 (phosphorylase kinase, delta)	approved	Phenoxybenzamine	CC(COC1=CC=CC=C1)N(CCCl)CC1=CC=CC=C1
CALM1	DB01023	calmodulin 1 (phosphorylase kinase, delta)	approved; investigational	Felodipine	CCOC(=O)C1=C(C)NC(C)=C(C1C1=C(Cl)C(Cl)=CC=C1)C(=O)OC
CALM1	DB01065	calmodulin 1 (phosphorylase kinase, delta)	approved; nutraceutical	Melatonin	COC1=CC2=C(NC=C2CCNC(C)=O)C=C1
CALM1	DB01069	calmodulin 1 (phosphorylase kinase, delta)	approved	Promethazine	CC(CN1C2=CC=CC=C2SC2=CC=CC=C12)N(C)C
CALM1	DB01100	calmodulin 1 (phosphorylase kinase, delta)	approved	Pimozide	FC1=CC=C(C=C1)C(CCCN1CCC(CC1)N1C(=O)NC2=CC=CC=C12)C1=CC=C(F)C=C1
CALM1	DB01115	calmodulin 1 (phosphorylase kinase, delta)	approved	Nifedipine	COC(=O)C1=C(C)NC(C)=C(C1C1=CC=CC=C1[N+]([O-])=O)C(=O)OC
CALM1	DB01244	calmodulin 1 (phosphorylase kinase, delta)	approved	Bepridil	CC(C)COCC(CN(CC1=CC=CC=C1)C1=CC=CC=C1)N1CCCC1
CALM1	DB01429	calmodulin 1 (phosphorylase kinase, delta)	approved	Aprindine	CCN(CC)CCCN(C1CC2=CC=CC=C2C1)C1=CC=CC=C1
CALM1	DB02868	calmodulin 1 (phosphorylase kinase, delta)	experimental	3''-(Beta-Chloroethyl)-2'',4''-Dioxo-3, 5''-Spiro-Oxazolidino-4-Deacetoxy-Vinblastine	CC[C@@]1(O)C[C@@H]2C[N@@](C1)CCc1c(nc3ccccc13)[C@@](C2)(C(=O)OC)C1=CC2=C(C=C1OC)N(C)[C@H]1[C@]3(C[C@@]4(CC)C=CCN5CC[C@@]21[C@@H]45)OC(=O)N(CCCl)C3=O
CALM1	DB03900	calmodulin 1 (phosphorylase kinase, delta)	experimental	2-Methyl-2-Propanol	CC(C)(C)O
CALM1	DB03977	calmodulin 1 (phosphorylase kinase, delta)	experimental	N-Trimethyllysine	C[N+](C)(C)CCCC[C@@H](N)C(O)=O
CALM1	DB04513	calmodulin 1 (phosphorylase kinase, delta)	experimental	N-(6-Aminohexyl)-5-Chloro-1-Naphthalenesulfonamide	NCCCCCCNS(=O)(=O)C1=CC=CC2=C1C=CC=C2Cl
CALM1	DB04825	calmodulin 1 (phosphorylase kinase, delta)	withdrawn	Prenylamine	CC(CC1=CC=CC=C1)NCCC(C1=CC=CC=C1)C1=CC=CC=C1
CALM1	DB04841	calmodulin 1 (phosphorylase kinase, delta)	approved	Flunarizine	FC1=CC=C(C=C1)C(N1CCN(C\C=C\C2=CC=CC=C2)CC1)C1=CC=C(F)C=C1
CALM1	DB08039	calmodulin 1 (phosphorylase kinase, delta)	experimental	(3Z)-N,N-DIMETHYL-2-OXO-3-(4,5,6,7-TETRAHYDRO-1H-INDOL-2-YLMETHYLIDENE)-2,3-DIHYDRO-1H-INDOLE-5-SULFONAMIDE	CN(C)S(=O)(=O)C1=CC=C2NC(=O)\C(=C/C3=CC4=C(CCCC4)N3)C2=C1
CALM1	DB08231	calmodulin 1 (phosphorylase kinase, delta)	experimental	MYRISTIC ACID	CCCCCCCCCCCCCC(O)=O
CALM1	DB00360	calmodulin 1 (phosphorylase kinase, delta)	approved; investigational	Tetrahydrobiopterin	CC(O)C(O)C1CNC2=C(N1)C(=O)N=C(N)N2
CALM1	DB00864	calmodulin 1 (phosphorylase kinase, delta)	approved; investigational	Tacrolimus	CO[C@@H]1C[C@@H](CC[C@H]1O)\C=C(/C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H]([C@H](C[C@H]2C)OC)[C@H](C[C@@H](C)C\C(C)=C\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]1C)OC
CALM1	DB00125	calmodulin 1 (phosphorylase kinase, delta)	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
CALM1	DB00435	calmodulin 1 (phosphorylase kinase, delta)	approved	Nitric Oxide	[N]=O
CALM2	DB00360	calmodulin 2 (phosphorylase kinase, delta)	approved; investigational	Tetrahydrobiopterin	CC(O)C(O)C1CNC2=C(N1)C(=O)N=C(N)N2
CALM2	DB00864	calmodulin 2 (phosphorylase kinase, delta)	approved; investigational	Tacrolimus	CO[C@@H]1C[C@@H](CC[C@H]1O)\C=C(/C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H]([C@H](C[C@H]2C)OC)[C@H](C[C@@H](C)C\C(C)=C\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]1C)OC
CALM2	DB00125	calmodulin 2 (phosphorylase kinase, delta)	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
CALM2	DB00435	calmodulin 2 (phosphorylase kinase, delta)	approved	Nitric Oxide	[N]=O
CALM3	DB00360	calmodulin 3 (phosphorylase kinase, delta)	approved; investigational	Tetrahydrobiopterin	CC(O)C(O)C1CNC2=C(N1)C(=O)N=C(N)N2
CALM3	DB00864	calmodulin 3 (phosphorylase kinase, delta)	approved; investigational	Tacrolimus	CO[C@@H]1C[C@@H](CC[C@H]1O)\C=C(/C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H]([C@H](C[C@H]2C)OC)[C@H](C[C@@H](C)C\C(C)=C\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]1C)OC
CALM3	DB00125	calmodulin 3 (phosphorylase kinase, delta)	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
CALM3	DB00435	calmodulin 3 (phosphorylase kinase, delta)	approved	Nitric Oxide	[N]=O
CALR	DB01065	calreticulin	approved; nutraceutical	Melatonin	COC1=CC2=C(NC=C2CCNC(C)=O)C=C1
CALR	DB00864	calreticulin	approved; investigational	Tacrolimus	CO[C@@H]1C[C@@H](CC[C@H]1O)\C=C(/C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H]([C@H](C[C@H]2C)OC)[C@H](C[C@@H](C)C\C(C)=C\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]1C)OC
CANT1	DB03486	calcium activated nucleotidase 1	experimental	Phosphomethylphosphonic Acid Guanosyl Ester	NC1=NC2=C(N=CN2[C@@H]2O[C@@H](CO[P@@](O)(=O)CP(O)(O)=O)[C@H](O)[C@H]2O)C(=O)N1
CANT1	DB03754	calcium activated nucleotidase 1	experimental	Tris(Hydroxymethyl)Aminomethane	[NH3+]C(CO)(CO)CO
CAT	DB01213	catalase	approved	Fomepizole	CC1=CNN=C1
CAT	DB03014	catalase	experimental	Heme	CC1=C(CCC(O)=O)C2=CC3=[N+]4C(=CC5=C(C=C)C(C)=C6C=C7C(C=C)=C(C)C8=[N+]7[Fe@]4(N2C1=C8)N56)C(C)=C3CCC(O)=O
CAT	DB02235	catalase	experimental	Methionine Sulfoxide	C[S@](=O)CC[C@@H](N)C(O)=O
CAT	DB01942	catalase	experimental	Formic Acid	OC=O
CAT	DB03790	catalase	experimental	S-Dioxymethionine	CS(=O)(=O)CC[C@@H](N)C(O)=O
CAT	DB00997	catalase	approved; investigational	Doxorubicin	COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3O[C@H]3C[C@H](N)[C@H](O)[C@H](C)O3)C(=O)CO)C(O)=C1C2=O
CAV1	DB00394	caveolin 1, caveolae protein, 22kDa	approved	Beclomethasone	C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
CAV1	DB00443	caveolin 1, caveolae protein, 22kDa	approved	Betamethasone	C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
CAV1	DB01222	caveolin 1, caveolae protein, 22kDa	approved; investigational	Budesonide	CCC[C@H]1O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO
CAV1	DB01410	caveolin 1, caveolae protein, 22kDa	approved; investigational	Ciclesonide	CC(C)C(=O)OCC(=O)[C@@]12OC(O[C@@H]1C[C@H]1[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@]21C)C1CCCCC1
CAV1	DB01260	caveolin 1, caveolae protein, 22kDa	approved; investigational	Desonide	CC1(C)O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO
CAV1	DB01234	caveolin 1, caveolae protein, 22kDa	approved; investigational	Dexamethasone	C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
CAV1	DB00180	caveolin 1, caveolae protein, 22kDa	approved; investigational	Flunisolide	CC1(C)O[C@@H]2C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO
CAV1	DB00588	caveolin 1, caveolae protein, 22kDa	approved; investigational	Fluticasone Propionate	CCC(=O)O[C@@]1([C@H](C)C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)C(=O)SCF
CAV1	DB00741	caveolin 1, caveolae protein, 22kDa	approved	Hydrocortisone	C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
CAV1	DB00959	caveolin 1, caveolae protein, 22kDa	approved	Methylprednisolone	C[C@H]1C[C@H]2[C@@H]3CC[C@](O)(C(=O)CO)[C@@]3(C)C[C@H](O)[C@@H]2[C@@]2(C)C=CC(=O)C=C12
CAV1	DB00764	caveolin 1, caveolae protein, 22kDa	approved	Mometasone	C[C@@H]1C[C@H]2C3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CCl
CAV1	DB01384	caveolin 1, caveolae protein, 22kDa	approved	Paramethasone	C[C@@H]1C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
CAV1	DB00860	caveolin 1, caveolae protein, 22kDa	approved	Prednisolone	C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
CAV1	DB00635	caveolin 1, caveolae protein, 22kDa	approved	Prednisone	C[C@]12CC(=O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
CAV1	DB00896	caveolin 1, caveolae protein, 22kDa	approved	Rimexolone	CCC(=O)[C@@]1(C)[C@H](C)CC2C3CCC4=CC(=O)C=C[C@]4(C)C3[C@@H](O)C[C@]12C
CAV1	DB00620	caveolin 1, caveolae protein, 22kDa	approved	Triamcinolone	C[C@]12C[C@H](O)[C@@]3(F)[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1C[C@@H](O)[C@]2(O)C(=O)CO
CAV1	DB00125	caveolin 1, caveolae protein, 22kDa	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
CAV1	DB00155	caveolin 1, caveolae protein, 22kDa	approved; nutraceutical	L-Citrulline	N[C@@H](CCCNC(N)=O)C(O)=O
CAV1	DB00435	caveolin 1, caveolae protein, 22kDa	approved	Nitric Oxide	[N]=O
CAV1	DB00131	caveolin 1, caveolae protein, 22kDa	approved; nutraceutical	Adenosine monophosphate	NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
CAV1	DB00171	caveolin 1, caveolae protein, 22kDa	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
CAV1	DB00360	caveolin 1, caveolae protein, 22kDa	approved; investigational	Tetrahydrobiopterin	CC(O)C(O)C1CNC2=C(N1)C(=O)N=C(N)N2
CBR1	DB03556	carbonyl reductase 1	experimental	2-(2-{2-[2-(2-{2-[2-(2-Ethoxy-Ethoxy)-Ethoxy]-Ethoxy}-Ethoxy)-Ethoxy]-Ethoxy}-Ethoxy)-Ethanol, Polyethyleneglycol Peg400	CCOCCOCCOCCOCCOCCOCCOCCOCCO
CBR1	DB04463	carbonyl reductase 1	experimental	3-(4-Amino-1-Tert-Butyl-1h-Pyrazolo[3,4-D]Pyrimidin-3-Yl)Phenol	CC(C)(C)N1N=C(C2=C(N)N=CN=C12)C1=CC=CC(O)=C1
CBR1	DB00694	carbonyl reductase 1	approved	Daunorubicin	COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3O[C@H]3C[C@H](N)[C@H](O)[C@H](C)O3)C(C)=O)C(O)=C1C2=O
CBR1	DB00997	carbonyl reductase 1	approved; investigational	Doxorubicin	COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3O[C@H]3C[C@H](N)[C@H](O)[C@H](C)O3)C(=O)CO)C(O)=C1C2=O
CBR3	DB00694	carbonyl reductase 3	approved	Daunorubicin	COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3O[C@H]3C[C@H](N)[C@H](O)[C@H](C)O3)C(C)=O)C(O)=C1C2=O
CBR3	DB00997	carbonyl reductase 3	approved; investigational	Doxorubicin	COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3O[C@H]3C[C@H](N)[C@H](O)[C@H](C)O3)C(=O)CO)C(O)=C1C2=O
CBR3	DB00445	carbonyl reductase 3	approved	Epirubicin	COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3O[C@H]3C[C@H](N)[C@@H](O)[C@H](C)O3)C(=O)CO)C(O)=C1C2=O
CBS	DB00114	cystathionine-beta-synthase	nutraceutical	Pyridoxal Phosphate	CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O
CBS	DB00118	cystathionine-beta-synthase	approved; nutraceutical	S-Adenosylmethionine	C[S+](CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C(N)N=CN=C12
CBS	DB00133	cystathionine-beta-synthase	approved; nutraceutical	L-Serine	N[C@@H](CO)C(O)=O
CBS	DB00151	cystathionine-beta-synthase	approved; nutraceutical	L-Cysteine	N[C@@H](CS)C(O)=O
CBS	DB00165	cystathionine-beta-synthase	approved; nutraceutical	Pyridoxine	CC1=NC=C(CO)C(CO)=C1O
CBS	DB03014	cystathionine-beta-synthase	experimental	Heme	CC1=C(CCC(O)=O)C2=CC3=[N+]4C(=CC5=C(C=C)C(C)=C6C=C7C(C=C)=C(C)C8=[N+]7[Fe@]4(N2C1=C8)N56)C(C)=C3CCC(O)=O
CBS	DB00175	cystathionine-beta-synthase	approved	Pravastatin	CC[C@H](C)C(=O)O[C@H]1C[C@H](O)C=C2C=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC(O)=O)[C@@H]12
CBS	DB00563	cystathionine-beta-synthase	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
CBS	DB00158	cystathionine-beta-synthase	approved; nutraceutical	Folic Acid	NC1=NC(=O)C2=NC(CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)=CN=C2N1
CCBL1	DB00114	cysteine conjugate-beta lyase, cytoplasmic	nutraceutical	Pyridoxal Phosphate	CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O
CCBL1	DB02142	cysteine conjugate-beta lyase, cytoplasmic	experimental	Pyridoxamine-5'-Phosphate	CC1=NC=C(COP(O)(O)=O)C(CN)=C1O
CCBL1	DB02556	cysteine conjugate-beta lyase, cytoplasmic	experimental	D-Phenylalanine	N[C@H](CC1=CC=CC=C1)C(O)=O
CCBL1	DB04083	cysteine conjugate-beta lyase, cytoplasmic	experimental	N'-Pyridoxyl-Lysine-5'-Monophosphate	CC1=NC=C(COP(O)(O)=O)C(CNCCCC[C@@H](N)C(O)=O)=C1O
CCBL1	DB07950	cysteine conjugate-beta lyase, cytoplasmic	experimental	1H-INDOL-3-YLACETIC ACID	OC(=O)CC1=CNC2=C1C=CC=C2
CCBL2	DB00114	cysteine conjugate-beta lyase 2	nutraceutical	Pyridoxal Phosphate	CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O
CCBL2	DB00142	cysteine conjugate-beta lyase 2	approved; nutraceutical	L-Glutamic Acid	N[C@@H](CCC(O)=O)C(O)=O
CDA	DB00987	cytidine deaminase	approved; investigational	Cytarabine	NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O
CDA	DB01101	cytidine deaminase	approved; investigational	Capecitabine	CCCCCOC(=O)NC1=NC(=O)N(C=C1F)[C@@H]1O[C@H](C)[C@@H](O)[C@H]1O
CDA	DB00544	cytidine deaminase	approved	Fluorouracil	FC1=CNC(=O)NC1=O
CDA	DB02745	cytidine deaminase	experimental	Uridine	OC[C@@H]1O[C@H]([C@H](O)[C@H]1O)N1C=CC(=O)NC1=O
CDA	DB00928	cytidine deaminase	approved; investigational	Azacitidine	NC1=NC(=O)N(C=N1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
CDA	DB00313	cytidine deaminase	approved; investigational	Valproic Acid	CCCC(CCC)C(O)=O
CDA	DB00441	cytidine deaminase	approved	Gemcitabine	NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](CO)[C@@H](O)C1(F)F
CDA	DB00515	cytidine deaminase	approved	Cisplatin	N[Pt](N)(Cl)Cl
CDIPT	DB03106	CDP-diacylglycerol--inositol 3-phosphatidyltransferase	experimental	Myo-Inositol	O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O
CDK8	DB03496	cyclin-dependent kinase 8	experimental; investigational	Flavopiridol	CN1CC[C@@H]([C@H](O)C1)C1=C(O)C=C(O)C2=C1OC(=CC2=O)C1=CC=CC=C1Cl
CDO1	DB00151	cysteine dioxygenase type 1	approved; nutraceutical	L-Cysteine	N[C@@H](CS)C(O)=O
CDO1	DB00157	cysteine dioxygenase type 1	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
CEPT1	DB00171	choline/ethanolamine phosphotransferase 1	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
CEPT1	DB00122	choline/ethanolamine phosphotransferase 1	approved; nutraceutical	Choline	C[N+](C)(C)CCO
CES1	DB00198	carboxylesterase 1	approved	Oseltamivir	CCOC(=O)C1=C[C@@H](OC(CC)CC)[C@H](NC(C)=O)[C@@H](N)C1
CES1	DB00583	carboxylesterase 1	approved	L-Carnitine	C[N+](C)(C)C[C@H](O)CC([O-])=O
CES1	DB01599	carboxylesterase 1	approved	Probucol	CC(C)(SC1=CC(=C(O)C(=C1)C(C)(C)C)C(C)(C)C)SC1=CC(=C(O)C(=C1)C(C)(C)C)C(C)(C)C
CES1	DB02161	carboxylesterase 1	experimental	Hydroxy-Phenyl-Acetic Acid 8-Methyl-8-Aza-Bicyclo[3.2.1]Oct-3-Yl Ester	CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)[C@H](O)C1=CC=CC=C1
CES1	DB02659	carboxylesterase 1	experimental	Cholic Acid	C[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C
CES1	DB02944	carboxylesterase 1	experimental	Alpha-D-Mannose	OC[C@@H]1O[C@H](O)[C@@H](O)[C@H](O)[C@H]1O
CES1	DB03056	carboxylesterase 1	experimental	4-Piperidino-Piperidine	C1CCN(CC1)C1CCNCC1
CES1	DB03721	carboxylesterase 1	experimental	O-Sialic Acid	CC(=O)N[C@H]1[C@H](O)C[C@](O)(O[C@@H]1[C@@H](O)[C@@H](O)CO)C(O)=O
CES1	DB04509	carboxylesterase 1	experimental	N-Methylnaloxonium	C[N@@+]1(CC=C)CC[C@]23[C@H]4OC5=C(O)C=CC(C[C@@H]1[C@]2(O)CCC4=O)=C35
CES1	DB04795	carboxylesterase 1	experimental	Thenoyltrifluoroacetone	FC(F)(F)C(=O)CC(=O)C1=CC=CS1
CES1	DB04838	carboxylesterase 1	approved	Cyclandelate	CC1CC(CC(C)(C)C1)OC(=O)C(O)C1=CC=CC=C1
CES1	DB07821	carboxylesterase 1	experimental	(1R)-1,2,2-TRIMETHYLPROPYL (R)-METHYLPHOSPHINATE	C[C@@H](OP(C)=O)C(C)(C)C
CES1	DB08224	carboxylesterase 1	experimental	(1S,7S,8S,8AR)-1,2,3,7,8,8A-HEXAHYDRO-7-METHYL-8-[2-[(2R,4R)-TETRAHYDRO-4-HY DROXY-6-OXO-2H-PYRAN-2-YL]ETHYL]-1-NAPHTHALENOL	C[C@H]1C=CC2=CCC[C@H](O)[C@@H]2[C@H]1CC[C@H]1C[C@@H](O)CC(=O)O1
CES1	DB00951	carboxylesterase 1	approved	Isoniazid	NNC(=O)C1=CC=NC=C1
CES1	DB00422	carboxylesterase 1	approved; investigational	Methylphenidate	COC(=O)C(C1CCCCN1)C1=CC=CC=C1
CES1	DB06209	carboxylesterase 1	approved; investigational	Prasugrel	CC(=O)OC1=CC2=C(CCN(C2)C(C(=O)C2CC2)C2=CC=CC=C2F)S1
CES1	DB01101	carboxylesterase 1	approved; investigational	Capecitabine	CCCCCOC(=O)NC1=NC(=O)N(C=C1F)[C@@H]1O[C@H](C)[C@@H](O)[C@H]1O
CES1	DB00544	carboxylesterase 1	approved	Fluorouracil	FC1=CNC(=O)NC1=O
CES1	DB00762	carboxylesterase 1	approved; investigational	Irinotecan	CCC1=C2CN3C(=CC4=C(COC(=O)[C@]4(O)CC)C3=O)C2=NC2=C1C=C(OC(=O)N1CCC(CC1)N1CCCCC1)C=C2
CES1	DB00519	carboxylesterase 1	approved	Trandolapril	CCOC(=O)[C@H](CCC1=CC=CC=C1)N[C@@H](C)C(=O)N1[C@H]2CCCC[C@@H]2C[C@H]1C(O)=O
CES2	DB00951	carboxylesterase 2	approved	Isoniazid	NNC(=O)C1=CC=NC=C1
CES2	DB06209	carboxylesterase 2	approved; investigational	Prasugrel	CC(=O)OC1=CC2=C(CCN(C2)C(C(=O)C2CC2)C2=CC=CC=C2F)S1
CES2	DB01101	carboxylesterase 2	approved; investigational	Capecitabine	CCCCCOC(=O)NC1=NC(=O)N(C=C1F)[C@@H]1O[C@H](C)[C@@H](O)[C@H]1O
CES2	DB00544	carboxylesterase 2	approved	Fluorouracil	FC1=CNC(=O)NC1=O
CES2	DB00762	carboxylesterase 2	approved; investigational	Irinotecan	CCC1=C2CN3C(=CC4=C(COC(=O)[C@]4(O)CC)C3=O)C2=NC2=C1C=C(OC(=O)N1CCC(CC1)N1CCCCC1)C=C2
CETP	DB01095	cholesteryl ester transfer protein, plasma	approved	Fluvastatin	CC(C)N1C(\C=C\[C@H](O)C[C@H](O)CC(O)=O)=C(C2=CC=C(F)C=C2)C2=CC=CC=C12
CETP	DB01076	cholesteryl ester transfer protein, plasma	approved	Atorvastatin	CC(C)C1=C(C(=O)NC2=CC=CC=C2)C(=C(N1CC[C@@H](O)C[C@@H](O)CC(O)=O)C1=CC=C(F)C=C1)C1=CC=CC=C1
CETP	DB00175	cholesteryl ester transfer protein, plasma	approved	Pravastatin	CC[C@H](C)C(=O)O[C@H]1C[C@H](O)C=C2C=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC(O)=O)[C@@H]12
CETP	DB00264	cholesteryl ester transfer protein, plasma	approved; investigational	Metoprolol	COCCC1=CC=C(OCC(O)CNC(C)C)C=C1
CGA	DB02944	glycoprotein hormones, alpha polypeptide	experimental	Alpha-D-Mannose	OC[C@@H]1O[C@H](O)[C@@H](O)[C@H](O)[C@H]1O
CGA	DB00451	glycoprotein hormones, alpha polypeptide	approved	Levothyroxine	N[C@@H](CC1=CC(I)=C(OC2=CC(I)=C(O)C(I)=C2)C(I)=C1)C(O)=O
CGB	DB01033	chorionic gonadotropin, beta polypeptide	approved	Mercaptopurine	S=C1N=CNC2=C1NC=N2
CGB	DB00563	chorionic gonadotropin, beta polypeptide	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
CHAT	DB00122	choline O-acetyltransferase	approved; nutraceutical	Choline	C[N+](C)(C)CCO
CHAT	DB01156	choline O-acetyltransferase	approved	Bupropion	CC(NC(C)(C)C)C(=O)C1=CC(Cl)=CC=C1
CHAT	DB03128	choline O-acetyltransferase	experimental	Acetylcholine	CC(=O)OCC[N+](C)(C)C
CHAT	DB00843	choline O-acetyltransferase	approved	Donepezil	COC1=C(OC)C=C2C(=O)C(CC3CCN(CC4=CC=CC=C4)CC3)CC2=C1
CHIA	DB03109	chitinase, acidic	experimental	N-Acetyl-D-Allosamine	CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@H](O)[C@@H]1O
CHIA	DB04404	chitinase, acidic	experimental	Allosamizoline	CN(C)C1=N[C@@H]2[C@@H](O)[C@@H](O)[C@H](CO)[C@@H]2O1
CHIA	DB04628	chitinase, acidic	experimental	Allosamidin	CN(C)C1=N[C@@H]2[C@@H](O)[C@H](O[C@@H]3O[C@H](CO)[C@@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@@H](O)[C@H]4NC(C)=O)[C@@H](O)[C@H]3NC(C)=O)[C@@H](CO)[C@@H]2O1
CHIT1	DB03109	chitinase 1 (chitotriosidase)	experimental	N-Acetyl-D-Allosamine	CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@H](O)[C@@H]1O
CHIT1	DB03539	chitinase 1 (chitotriosidase)	experimental	2-(Acetylamino)-2-Deoxy-6-O-Methyl-Alpha-D-Allopyranose	OC[C@H]1[C@H](O)[C@@H](O)[C@H]2N=C(O[C@@H]12)N=C
CHIT1	DB03632	chitinase 1 (chitotriosidase)	experimental	Argifin	CNC(=O)NC(=N)NCCC[C@H]1NC(=O)[C@@H](C)NC(=O)C[C@@H](NC(=O)C[C@@H](NC(=O)[C@@H](CC2=CC=CC=C2)N(C)C1=O)C(O)=O)C(O)=O
CHIT1	DB04350	chitinase 1 (chitotriosidase)	experimental	Argadin	CC(=O)N\C(N)=N\CCC[C@@H]1NC(=O)[C@H](CCCC(O)=O)NC(=O)[C@H](CC2=CN=CN2)N2[C@H](O)C[C@H](NC(=O)[C@H]3CCCN3C1=O)C2=O
CHIT1	DB04404	chitinase 1 (chitotriosidase)	experimental	Allosamizoline	CN(C)C1=N[C@@H]2[C@@H](O)[C@@H](O)[C@H](CO)[C@@H]2O1
CHKA	DB00171	choline kinase alpha	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
CHKA	DB00122	choline kinase alpha	approved; nutraceutical	Choline	C[N+](C)(C)CCO
CHPT1	DB00709	choline phosphotransferase 1	approved; investigational	Lamivudine	NC1=NC(=O)N(C=C1)[C@@H]1CS[C@H](CO)O1
CHRM3	DB00185	cholinergic receptor, muscarinic 3	approved	Cevimeline	C[C@@H]1O[C@@]2(CS1)CN1CCC2CC1
CHRM3	DB00193	cholinergic receptor, muscarinic 3	approved; investigational	Tramadol	COC1=CC=CC(=C1)[C@@]1(O)CCCC[C@@H]1CN(C)C
CHRM3	DB00202	cholinergic receptor, muscarinic 3	approved	Succinylcholine	C[N+](C)(C)CCOC(=O)CCC(=O)OCC[N+](C)(C)C
CHRM3	DB00246	cholinergic receptor, muscarinic 3	approved	Ziprasidone	ClC1=C(CCN2CCN(CC2)C2=NSC3=CC=CC=C23)C=C2CC(=O)NC2=C1
CHRM3	DB00280	cholinergic receptor, muscarinic 3	approved	Disopyramide	CC(C)N(CCC(C(N)=O)(C1=CC=CC=C1)C1=CC=CC=N1)C(C)C
CHRM3	DB00321	cholinergic receptor, muscarinic 3	approved	Amitriptyline	CN(C)CCC=C1C2=CC=CC=C2CCC2=CC=CC=C12
CHRM3	DB00332	cholinergic receptor, muscarinic 3	approved	Ipratropium bromide	CC(C)[N+]1(C)[C@@H]2CC[C@@H]1CC(C2)OC(=O)C(CO)C1=CC=CC=C1
CHRM3	DB00334	cholinergic receptor, muscarinic 3	approved; investigational	Olanzapine	CN1CCN(CC1)C1=C2C=C(C)SC2=NC2=CC=CC=C2N1
CHRM3	DB00340	cholinergic receptor, muscarinic 3	approved	Metixene	CN1CCCC(CC2C3=CC=CC=C3SC3=CC=CC=C23)C1
CHRM3	DB00342	cholinergic receptor, muscarinic 3	approved; withdrawn	Terfenadine	CC(C)(C)C1=CC=C(C=C1)C(O)CCCN1CCC(CC1)C(O)(C1=CC=CC=C1)C1=CC=CC=C1
CHRM3	DB00363	cholinergic receptor, muscarinic 3	approved	Clozapine	CN1CCN(CC1)C1=NC2=CC(Cl)=CC=C2NC2=CC=CC=C12
CHRM3	DB00376	cholinergic receptor, muscarinic 3	approved	Trihexyphenidyl	OC(CCN1CCCCC1)(C1CCCCC1)C1=CC=CC=C1
CHRM3	DB00383	cholinergic receptor, muscarinic 3	approved	Oxyphencyclimine	CN1CCCN=C1COC(=O)C(O)(C1CCCCC1)C1=CC=CC=C1
CHRM3	DB00387	cholinergic receptor, muscarinic 3	approved	Procyclidine	OC(CCN1CCCC1)(C1CCCCC1)C1=CC=CC=C1
CHRM3	DB00420	cholinergic receptor, muscarinic 3	approved	Promazine	CN(C)CCCN1C2=CC=CC=C2SC2=CC=CC=C12
CHRM3	DB00424	cholinergic receptor, muscarinic 3	approved	Hyoscyamine	CN1C2CCC1CC(C2)OC(=O)[C@H](CO)C1=CC=CC=C1
CHRM3	DB00434	cholinergic receptor, muscarinic 3	approved	Cyproheptadine	CN1CCC(CC1)=C1C2=CC=CC=C2C=CC2=CC=CC=C12
CHRM3	DB00458	cholinergic receptor, muscarinic 3	approved	Imipramine	CN(C)CCCN1C2=CC=CC=C2CCC2=CC=CC=C12
CHRM3	DB00462	cholinergic receptor, muscarinic 3	approved	Methylscopolamine	[Br-].C[N+]1(C)[C@H]2C[C@@H](C[C@H]1C1OC21)OC(=O)[C@H](CO)C1=CC=CC=C1
CHRM3	DB00496	cholinergic receptor, muscarinic 3	approved; investigational	Darifenacin	NC(=O)C([C@@H]1CCN(CCC2=CC3=C(OCC3)C=C2)C1)(C1=CC=CC=C1)C1=CC=CC=C1
CHRM3	DB00505	cholinergic receptor, muscarinic 3	approved	Tridihexethyl	CC[N+](CC)(CC)CCC(O)(C1CCCCC1)C1=CC=CC=C1
CHRM3	DB00517	cholinergic receptor, muscarinic 3	approved	Anisotropine Methylbromide	[Br-].CCCC(CCC)C(=O)O[C@@H]1C[C@@H]2CC[C@H](C1)[N+]2(C)C
CHRM3	DB00540	cholinergic receptor, muscarinic 3	approved	Nortriptyline	CNCCC=C1C2=CC=CC=C2CCC2=CC=CC=C12
CHRM3	DB00572	cholinergic receptor, muscarinic 3	approved	Atropine	CN1[C@H]2CC[C@@H]1CC(C2)OC(=O)C(CO)C1=CC=CC=C1
CHRM3	DB00622	cholinergic receptor, muscarinic 3	approved	Nicardipine	COC(=O)C1=C(C)NC(C)=C(C1C1=CC(=CC=C1)[N+]([O-])=O)C(=O)OCCN(C)CC1=CC=CC=C1
CHRM3	DB00715	cholinergic receptor, muscarinic 3	approved; investigational	Paroxetine	FC1=CC=C(C=C1)[C@@H]1CCNC[C@H]1COC1=CC2=C(OCO2)C=C1
CHRM3	DB00725	cholinergic receptor, muscarinic 3	approved	Homatropine Methylbromide	[Br-].C[N+]1(C)[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)C(O)C1=CC=CC=C1
CHRM3	DB00729	cholinergic receptor, muscarinic 3	approved	Diphemanil Methylsulfate	COS([O-])(=O)=O.C[N+]1(C)CCC(CC1)=C(C1=CC=CC=C1)C1=CC=CC=C1
CHRM3	DB00747	cholinergic receptor, muscarinic 3	approved	Scopolamine	CN1C2CC(CC1C1OC21)OC(=O)C(CO)C1=CC=CC=C1
CHRM3	DB00767	cholinergic receptor, muscarinic 3	approved	Benzquinamide	CCN(CC)C(=O)C1CN2CCC3=CC(OC)=C(OC)C=C3C2CC1OC(C)=O
CHRM3	DB00777	cholinergic receptor, muscarinic 3	approved	Propiomazine	CCC(=O)C1=CC2=C(SC3=CC=CC=C3N2CC(C)N(C)C)C=C1
CHRM3	DB00809	cholinergic receptor, muscarinic 3	approved	Tropicamide	CCN(CC1=CC=NC=C1)C(=O)C(CO)C1=CC=CC=C1
CHRM3	DB00835	cholinergic receptor, muscarinic 3	approved	Brompheniramine	CN(C)CCC(C1=CC=C(Br)C=C1)C1=CC=CC=N1
CHRM3	DB00934	cholinergic receptor, muscarinic 3	approved	Maprotiline	CNCCCC12CCC(C3=CC=CC=C13)C1=CC=CC=C21
CHRM3	DB01036	cholinergic receptor, muscarinic 3	approved; investigational	Tolterodine	CC(C)N(CC[C@@H](C1=CC=CC=C1)C1=C(O)C=CC(C)=C1)C(C)C
CHRM3	DB01062	cholinergic receptor, muscarinic 3	approved; investigational	Oxybutynin	CCN(CC)CC#CCOC(=O)C(O)(C1CCCCC1)C1=CC=CC=C1
CHRM3	DB01069	cholinergic receptor, muscarinic 3	approved	Promethazine	CC(CN1C2=CC=CC=C2SC2=CC=CC=C12)N(C)C
CHRM3	DB01085	cholinergic receptor, muscarinic 3	approved	Pilocarpine	CC[C@H]1[C@@H](CC2=CN=CN2C)COC1=O
CHRM3	DB01142	cholinergic receptor, muscarinic 3	approved	Doxepin	CN(C)CC\C=C1/C2=CC=CC=C2COC2=CC=CC=C12
CHRM3	DB01151	cholinergic receptor, muscarinic 3	approved	Desipramine	CNCCCN1C2=CC=CC=C2CCC2=CC=CC=C12
CHRM3	DB01224	cholinergic receptor, muscarinic 3	approved	Quetiapine	OCCOCCN1CCN(CC1)C1=NC2=CC=CC=C2SC2=CC=CC=C12
CHRM3	DB01226	cholinergic receptor, muscarinic 3	approved	Mivacurium	COC1=CC(C[C@@H]2C3=CC(OC)=C(OC)C=C3CC[N+]2(C)CCCOC(=O)CC\C=C\CCC(=O)OCCC[N+]2(C)CCC3=CC(OC)=C(OC)C=C3[C@H]2CC2=CC(OC)=C(OC)C(OC)=C2)=CC(OC)=C1OC
CHRM3	DB01231	cholinergic receptor, muscarinic 3	approved	Diphenidol	OC(CCCN1CCCCC1)(C1=CC=CC=C1)C1=CC=CC=C1
CHRM3	DB01238	cholinergic receptor, muscarinic 3	approved; investigational	Aripiprazole	ClC1=CC=CC(N2CCN(CCCCOC3=CC4=C(CCC(=O)N4)C=C3)CC2)=C1Cl
CHRM3	DB01239	cholinergic receptor, muscarinic 3	approved	Chlorprothixene	CN(C)CCC=C1C2=CC=CC=C2SC2=C1C=C(Cl)C=C2
CHRM3	DB01337	cholinergic receptor, muscarinic 3	approved	Pancuronium	CC(=O)O[C@H]1[C@H](C[C@H]2[C@@H]3CC[C@H]4C[C@H](OC(C)=O)[C@H](C[C@]4(C)[C@H]3CC[C@]12C)[N+]1(C)CCCCC1)[N+]1(C)CCCCC1
CHRM3	DB01338	cholinergic receptor, muscarinic 3	approved	Pipecuronium	CC(=O)O[C@H]1[C@H](C[C@H]2[C@@H]3CC[C@H]4C[C@H](OC(C)=O)[C@H](C[C@]4(C)[C@H]3CC[C@]12C)N1CC[N+](C)(C)CC1)N1CC[N+](C)(C)CC1
CHRM3	DB01403	cholinergic receptor, muscarinic 3	approved	Methotrimeprazine	COC1=CC2=C(SC3=C(C=CC=C3)N2C[C@H](C)CN(C)C)C=C1
CHRM3	DB01409	cholinergic receptor, muscarinic 3	approved	Tiotropium	C[N+]1(C)[C@H]2CC(C[C@@H]1[C@@H]1O[C@H]21)OC(=O)C(O)(C1=CC=CS1)C1=CC=CS1
CHRM3	DB01591	cholinergic receptor, muscarinic 3	approved	Solifenacin	OC(=O)CCC(O)=O.O=C(O[C@H]1CN2CCC1CC2)N1CCC2=CC=CC=C2[C@@H]1C1=CC=CC=C1
CHRM3	DB01625	cholinergic receptor, muscarinic 3	approved	Isopropamide	CC(C)[N+](C)(CCC(C(N)=O)(C1=CC=CC=C1)C1=CC=CC=C1)C(C)C
CHRM3	DB04843	cholinergic receptor, muscarinic 3	approved	Mepenzolate	C[N+]1(C)CCCC(C1)OC(=O)C(O)(C1=CC=CC=C1)C1=CC=CC=C1
CHRM3	DB06702	cholinergic receptor, muscarinic 3	approved	Fesoterodine	CC(C)N(CC[C@H](C1=CC=CC=C1)C1=C(OC(=O)C(C)C)C=CC(CO)=C1)C(C)C
CHRM3	DB06709	cholinergic receptor, muscarinic 3	approved	Methacholine	CC(C[N+](C)(C)C)OC(C)=O
CHST1	DB01033	carbohydrate (keratan sulfate Gal-6) sulfotransferase 1	approved	Mercaptopurine	S=C1N=CNC2=C1NC=N2
CHST1	DB00563	carbohydrate (keratan sulfate Gal-6) sulfotransferase 1	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
CHST3	DB01248	carbohydrate (chondroitin 6) sulfotransferase 3	approved; investigational	Docetaxel	CC(=O)O[C@@]12CO[C@@H]1C[C@H](O)[C@]1(C)[C@@H]2[C@H](OC(=O)C2=CC=CC=C2)[C@]2(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C3=CC=CC=C3)C(C)=C([C@@H](O)C1=O)C2(C)C
CHST3	DB01041	carbohydrate (chondroitin 6) sulfotransferase 3	approved; withdrawn; investigational	Thalidomide	O=C1N(C2CCC(=O)NC2=O)C(=O)C2=CC=CC=C12
CKB	DB00148	creatine kinase, brain	approved; nutraceutical	Creatine	CN(CC(O)=O)C(N)=N
CKM	DB00148	creatine kinase, muscle	approved; nutraceutical	Creatine	CN(CC(O)=O)C(N)=N
CKM	DB02490	creatine kinase, muscle	experimental	(Diaminomethyl-Methyl-Amino)-Acetic Acid	CN(CC(O)=O)C(N)N
CKM	DB03431	creatine kinase, muscle	experimental	Adenosine-5'-Diphosphate	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](CO[P@](O)(=O)OP(O)(O)=O)[C@H](O)[C@H]1O
CKM	DB04027	creatine kinase, muscle	experimental	D-Arginine	N[C@@H](CCCNC(N)=[NH2+])C(O)=O
CKMT1A	DB00148	creatine kinase, mitochondrial 1A	approved; nutraceutical	Creatine	CN(CC(O)=O)C(N)=N
CKMT2	DB00148	creatine kinase, mitochondrial 2 (sarcomeric)	approved; nutraceutical	Creatine	CN(CC(O)=O)C(N)=N
CLPS	DB04233	colipase, pancreatic	experimental	(Hydroxyethyloxy)Tri(Ethyloxy)Octane	CCCCCCCCOCCOCCOCCOCCO
CLPS	DB08222	colipase, pancreatic	experimental	METHOXYUNDECYLPHOSPHINIC ACID	CCCCCCCCCCC[P@@](O)(=O)OC
CMAS	DB04555	cytidine monophosphate N-acetylneuraminic acid synthetase	experimental	Cytidine-5'-Diphosphate	NC1=NC(=O)N(C=C1)[C@@H]1O[C@@H](CO[P@](O)(=O)OP(O)(O)=O)[C@H](O)[C@H]1O
CMPK1	DB00441	cytidine monophosphate (UMP-CMP) kinase 1, cytosolic	approved	Gemcitabine	NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](CO)[C@@H](O)C1(F)F
CMPK1	DB03403	cytidine monophosphate (UMP-CMP) kinase 1, cytosolic	experimental	Cytidine-5'-Monophosphate	NC1=NC(=O)N(C=C1)[C@@H]1O[C@@H](COP(O)(O)=O)[C@H](O)[C@H]1O
CMPK1	DB03431	cytidine monophosphate (UMP-CMP) kinase 1, cytosolic	experimental	Adenosine-5'-Diphosphate	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](CO[P@](O)(=O)OP(O)(O)=O)[C@H](O)[C@H]1O
CMPK1	DB03435	cytidine monophosphate (UMP-CMP) kinase 1, cytosolic	experimental	Uridine-5'-Diphosphate	O[C@@H]1[C@@H](O)[C@@H](O[C@H]1CO[P@](O)(=O)OP(O)(O)=O)N1C=CC(=O)NC1=O
CMPK1	DB03664	cytidine monophosphate (UMP-CMP) kinase 1, cytosolic	experimental	P1-(Adenosine-5'-P5-(Uridine-5')Pentaphosphate	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](CO[P@](O)(=O)O[P@@](O)(=O)O[P@](O)(=O)O[P@](O)(=O)O[P@@](O)(=O)OC[C@@H]2O[C@H]([C@H](O)[C@H]2O)N2C=CC(=O)NC2=O)[C@H](O)[C@H]1O
CMPK1	DB04444	cytidine monophosphate (UMP-CMP) kinase 1, cytosolic	experimental	Tetrafluoroaluminate Ion	F[Al](F)(F)[F-]
CMPK1	DB00987	cytidine monophosphate (UMP-CMP) kinase 1, cytosolic	approved; investigational	Cytarabine	NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O
CMPK1	DB00709	cytidine monophosphate (UMP-CMP) kinase 1, cytosolic	approved; investigational	Lamivudine	NC1=NC(=O)N(C=C1)[C@@H]1CS[C@H](CO)O1
CMPK1	DB00544	cytidine monophosphate (UMP-CMP) kinase 1, cytosolic	approved	Fluorouracil	FC1=CNC(=O)NC1=O
CMPK1	DB00130	cytidine monophosphate (UMP-CMP) kinase 1, cytosolic	approved; nutraceutical; investigational	L-Glutamine	N[C@@H](CCC(N)=O)C(O)=O
CNOT8	DB01033	CCR4-NOT transcription complex, subunit 8	approved	Mercaptopurine	S=C1N=CNC2=C1NC=N2
CNOT8	DB00563	CCR4-NOT transcription complex, subunit 8	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
COASY	DB00151	CoA synthase	approved; nutraceutical	L-Cysteine	N[C@@H](CS)C(O)=O
COMT	DB00118	catechol-O-methyltransferase	approved; nutraceutical	S-Adenosylmethionine	C[S+](CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C(N)N=CN=C12
COMT	DB00323	catechol-O-methyltransferase	approved; withdrawn	Tolcapone	CC1=CC=C(C=C1)C(=O)C1=CC(=C(O)C(O)=C1)[N+]([O-])=O
COMT	DB00494	catechol-O-methyltransferase	approved; investigational	Entacapone	CCN(CC)C(=O)C(=C\C1=CC(=C(O)C(O)=C1)[N+]([O-])=O)\C#N
COMT	DB02105	catechol-O-methyltransferase	experimental	3,5-Dinitrocatechol	OC1=CC(=CC(=C1O)[N+]([O-])=O)[N+]([O-])=O
COMT	DB03336	catechol-O-methyltransferase	experimental	BIA	OC1=CC(=CC(=C1O)[N+]([O-])=O)C(=O)CCN1CCN(CC1)C1=CC(=CC=C1)C(F)(F)F
COMT	DB03907	catechol-O-methyltransferase	experimental	N-{3-[5-(6-Amino-Purin-9-Yl)-3,4-Dihydroxy-Tetrahydro-Furan-2-Yl]-Allyl}-2,3-Dihydroxy-5-Nitro-Benzamide	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](\C=C\CNC(=O)C2=CC(=CC(O)=C2O)[N](O)=O)[C@H](O)[C@H]1O
COMT	DB04820	catechol-O-methyltransferase	withdrawn	Nialamide	O=C(CCNNC(=O)C1=CC=NC=C1)NCC1=CC=CC=C1
COMT	DB07462	catechol-O-methyltransferase	experimental	(3,4-DIHYDROXY-2-NITROPHENYL)(PHENYL)METHANONE	OC1=CC=C(C(=O)C2=CC=CC=C2)C(=C1O)[N+]([O-])=O
COMT	DB08049	catechol-O-methyltransferase	experimental	7,8-dihydroxy-4-phenyl-2H-chromen-2-one	OC1=CC=C2C(OC(=O)C=C2C2=CC=CC=C2)=C1O
COMT	DB00286	catechol-O-methyltransferase	approved	Conjugated Estrogens	[Na+].C[C@]12CC[C@H]3[C@@H](CCC4=CC(OS([O-])(=O)=O)=CC=C34)[C@@H]1CCC2=O
COMT	DB00571	catechol-O-methyltransferase	approved; investigational	Propranolol	CC(C)NCC(O)COC1=CC=CC2=CC=CC=C12
COMT	DB00215	catechol-O-methyltransferase	approved	Citalopram	CN(C)CCCC1(OCC2=C1C=CC(=C2)C#N)C1=CC=C(F)C=C1
COMT	DB00472	catechol-O-methyltransferase	approved	Fluoxetine	CNCCC(OC1=CC=C(C=C1)C(F)(F)F)C1=CC=CC=C1
COMT	DB00988	catechol-O-methyltransferase	approved	Dopamine	NCCC1=CC(O)=C(O)C=C1
COMT	DB00318	catechol-O-methyltransferase	illicit; approved	Codeine	COC1=C2O[C@H]3[C@@H](O)C=C[C@H]4[C@H]5CC(C=C1)=C2[C@@]34CCN5C
COMT	DB00907	catechol-O-methyltransferase	illicit; approved	Cocaine	COC(=O)[C@@H]1C2CCC(C[C@@H]1OC(=O)C1=CC=CC=C1)N2C
COMT	DB00476	catechol-O-methyltransferase	approved	Duloxetine	CNCC[C@H](OC1=CC=CC2=CC=CC=C12)C1=CC=CS1
COMT	DB00864	catechol-O-methyltransferase	approved; investigational	Tacrolimus	CO[C@@H]1C[C@@H](CC[C@H]1O)\C=C(/C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H]([C@H](C[C@H]2C)OC)[C@H](C[C@@H](C)C\C(C)=C\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]1C)OC
COMT	DB00640	catechol-O-methyltransferase	approved; investigational	Adenosine	NC1=C2N=CN([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)C2=NC=N1
COMT	DB00134	catechol-O-methyltransferase	approved; nutraceutical	L-Methionine	CSCC[C@H](N)C(O)=O
COMT	DB01156	catechol-O-methyltransferase	approved	Bupropion	CC(NC(C)(C)C)C(=O)C1=CC(Cl)=CC=C1
COMT	DB00334	catechol-O-methyltransferase	approved; investigational	Olanzapine	CN1CCN(CC1)C1=C2C=C(C)SC2=NC2=CC=CC=C2N1
COMT	DB01452	catechol-O-methyltransferase	illicit; experimental	Heroin	CN1CC[C@]23[C@H]4OC5=C(OC(C)=O)C=CC(C[C@@H]1[C@@H]2C=C[C@@H]4OC(C)=O)=C35
COMT	DB00734	catechol-O-methyltransferase	approved; investigational	Risperidone	CC1=C(CCN2CCC(CC2)C2=NOC3=C2C=CC(F)=C3)C(=O)N2CCCCC2=N1
COMT	DB00295	catechol-O-methyltransferase	approved; investigational	Morphine	CN1CC[C@]23[C@H]4OC5=C(O)C=CC(C[C@@H]1[C@@H]2C=C[C@@H]4O)=C35
COMT	DB00745	catechol-O-methyltransferase	approved; investigational	Modafinil	NC(=O)CS(=O)C(C1=CC=CC=C1)C1=CC=CC=C1
COMT	DB00115	catechol-O-methyltransferase	approved; nutraceutical	Cyanocobalamin	[C@@H]1([C@H]2N3C4=C(C5=[N]6C(C([C@@H]5CCC(N)=O)(C)C)=CC5=[N]7C(=C(C8=[N]([C@@]2([C@@]([C@@H]8CCC(N)=O)(C)CC(N)=O)C)[Co]367([N]2=CN(C3=CC(=C(C)C=C23)C)[C@H]2O[C@H](CO)[C@@H](OP(O)(=O)O[C@H](C)CNC(=O)CC[C@]14C)[C@H]2O)C#N)C)[C@@]([C@@H]5CCC(N)=O)(C)CC(N)=O)C)CC(N)=O
COMT	DB00158	catechol-O-methyltransferase	approved; nutraceutical	Folic Acid	NC1=NC(=O)C2=NC(CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)=CN=C2N1
COMT	DB01454	catechol-O-methyltransferase	illicit; experimental	3,4-Methylenedioxymethamphetamine	CNC(C)CC1=CC2=C(OCO2)C=C1
COMT	DB01235	catechol-O-methyltransferase	approved	Levodopa	N[C@@H](CC1=CC(O)=C(O)C=C1)C(O)=O
COMT	DB00668	catechol-O-methyltransferase	approved	Epinephrine	CNC[C@H](O)C1=CC(O)=C(O)C=C1
COMT	DB01033	catechol-O-methyltransferase	approved	Mercaptopurine	S=C1N=CNC2=C1NC=N2
COMT	DB00945	catechol-O-methyltransferase	approved	Acetylsalicylic acid	CC(=O)OC1=CC=CC=C1C(O)=O
COMT	DB00968	catechol-O-methyltransferase	approved	Methyldopa	C[C@](N)(CC1=CC(O)=C(O)C=C1)C(O)=O
COMT	DB00184	catechol-O-methyltransferase	approved	Nicotine	CN1CCCC1C1=CN=CC=C1
COMT	DB00515	catechol-O-methyltransferase	approved	Cisplatin	N[Pt](N)(Cl)Cl
COMT	DB00422	catechol-O-methyltransferase	approved; investigational	Methylphenidate	COC(=O)C(C1CCCCN1)C1=CC=CC=C1
CP	DB01033	ceruloplasmin (ferroxidase)	approved	Mercaptopurine	S=C1N=CNC2=C1NC=N2
CP	DB00563	ceruloplasmin (ferroxidase)	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
CPOX	DB03766	coproporphyrinogen oxidase	experimental	Propanoic Acid	CCC(O)=O
CPOX	DB03793	coproporphyrinogen oxidase	experimental	Benzoic Acid	OC(=O)C1=CC=CC=C1
CPOX	DB00145	coproporphyrinogen oxidase	approved; nutraceutical	Glycine	NCC(O)=O
CPS1	DB00125	carbamoyl-phosphate synthase 1, mitochondrial	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
CPS1	DB03904	carbamoyl-phosphate synthase 1, mitochondrial	experimental	Urea	NC(N)=O
CPT1A	DB00583	carnitine palmitoyltransferase 1A (liver)	approved	L-Carnitine	C[N+](C)(C)C[C@H](O)CC([O-])=O
CPT1A	DB01074	carnitine palmitoyltransferase 1A (liver)	approved	Perhexiline	C(C(C1CCCCC1)C1CCCCC1)C1CCCCN1
CPT2	DB00583	carnitine palmitoyltransferase 2	approved	L-Carnitine	C[N+](C)(C)C[C@H](O)CC([O-])=O
CPT2	DB01074	carnitine palmitoyltransferase 2	approved	Perhexiline	C(C(C1CCCCC1)C1CCCCC1)C1CCCCN1
CPT2	DB01076	carnitine palmitoyltransferase 2	approved	Atorvastatin	CC(C)C1=C(C(=O)NC2=CC=CC=C2)C(=C(N1CC[C@@H](O)C[C@@H](O)CC(O)=O)C1=CC=C(F)C=C1)C1=CC=CC=C1
CPT2	DB00439	carnitine palmitoyltransferase 2	withdrawn	Cerivastatin	COCC1=C(C2=CC=C(F)C=C2)C(\C=C\[C@@H](O)C[C@@H](O)CC(O)=O)=C(C(C)C)N=C1C(C)C
CPT2	DB01095	carnitine palmitoyltransferase 2	approved	Fluvastatin	CC(C)N1C(\C=C\[C@H](O)C[C@H](O)CC(O)=O)=C(C2=CC=C(F)C=C2)C2=CC=CC=C12
CPT2	DB00175	carnitine palmitoyltransferase 2	approved	Pravastatin	CC[C@H](C)C(=O)O[C@H]1C[C@H](O)C=C2C=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC(O)=O)[C@@H]12
CPT2	DB01098	carnitine palmitoyltransferase 2	approved	Rosuvastatin	CC(C)C1=NC(=NC(C2=CC=C(F)C=C2)=C1\C=C\[C@H](O)C[C@@H](O)CC(O)=O)N(C)S(=O)(=O)C
CPT2	DB00641	carnitine palmitoyltransferase 2	approved	Simvastatin	CCC(C)(C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CCC3C[C@@H](O)CC(=O)O3)[C@@H]12
CRAT	DB00583	carnitine O-acetyltransferase	approved	L-Carnitine	C[N+](C)(C)C[C@H](O)CC([O-])=O
CRAT	DB01992	carnitine O-acetyltransferase	experimental	Coenzyme A	CC(C)(CO[P@](O)(=O)O[P@@](O)(=O)OC[C@@H]1O[C@H]([C@H](O)[C@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N)[C@@H](O)C(=O)NCCC(=O)NCCS
CRAT	DB02648	carnitine O-acetyltransferase	experimental	(3-Carboxy-2-(R)-Hydroxy-Propyl)-Trimethyl-Ammonium	C[N+](C)(C)C[C@H](O)CC(O)=O
CREBBP	DB00619	CREB binding protein	approved	Imatinib	CN1CCN(CC2=CC=C(C=C2)C(=O)NC2=CC(NC3=NC=CC(=N3)C3=CN=CC=C3)=C(C)C=C2)CC1
CREBBP	DB01234	CREB binding protein	approved; investigational	Dexamethasone	C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
CREBBP	DB00864	CREB binding protein	approved; investigational	Tacrolimus	CO[C@@H]1C[C@@H](CC[C@H]1O)\C=C(/C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H]([C@H](C[C@H]2C)OC)[C@H](C[C@@H](C)C\C(C)=C\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]1C)OC
CREBBP	DB00171	CREB binding protein	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
CREBBP	DB00269	CREB binding protein	approved	Chlorotrianisene	COC1=CC=C(C=C1)C(Cl)=C(C1=CC=C(OC)C=C1)C1=CC=C(OC)C=C1
CREBBP	DB00286	CREB binding protein	approved	Conjugated Estrogens	[Na+].C[C@]12CC[C@H]3[C@@H](CCC4=CC(OS([O-])(=O)=O)=CC=C34)[C@@H]1CCC2=O
CREBBP	DB00890	CREB binding protein	approved	Dienestrol	CC=C(C(=CC)C1=CC=C(O)C=C1)C1=CC=C(O)C=C1
CREBBP	DB00255	CREB binding protein	approved	Diethylstilbestrol	CCC(=C(CC)C1=CC=C(O)C=C1)C1=CC=C(O)C=C1
CREBBP	DB00783	CREB binding protein	approved; investigational	Estradiol	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CC[C@@H]2O
CREBBP	DB00655	CREB binding protein	approved	Estrone	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CCC2=O
CREBBP	DB00977	CREB binding protein	approved	Ethinyl Estradiol	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CC[C@@]2(O)C#C
CROT	DB00583	carnitine O-octanoyltransferase	approved	L-Carnitine	C[N+](C)(C)C[C@H](O)CC([O-])=O
CROT	DB02648	carnitine O-octanoyltransferase	experimental	(3-Carboxy-2-(R)-Hydroxy-Propyl)-Trimethyl-Ammonium	C[N+](C)(C)C[C@H](O)CC(O)=O
CROT	DB03832	carnitine O-octanoyltransferase	experimental	3-Carboxy-N,N,N-Trimethyl-2-(Octanoyloxy)Propan-1-Aminium	CCCCCCCC(=O)O[C@@H](CC(O)=O)C[N+](C)(C)C
CSAD	DB00114	cysteine sulfinic acid decarboxylase	nutraceutical	Pyridoxal Phosphate	CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O
CSAD	DB00151	cysteine sulfinic acid decarboxylase	approved; nutraceutical	L-Cysteine	N[C@@H](CS)C(O)=O
CSNK1G2	DB03083	casein kinase 1, gamma 2	experimental	IC261	COC1=CC(OC)=C(\C=C2\C(=O)NC3=CC=CC=C23)C(OC)=C1
CSNK1G2	DB03693	casein kinase 1, gamma 2	experimental	N-(2-Aminoethyl)-5-Chloroisoquinoline-8-Sulfonamide	NCCNS(=O)(=O)C1=CC=C(Cl)C2=C1C=NC=C2
CSNK1G2	DB04604	casein kinase 1, gamma 2	experimental	5-iodotubercidin	NC1=C2C(I)=CN([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)C2=NC=N1
CTGF	DB02010	connective tissue growth factor	experimental	Staurosporine	CN[C@@H]1C[C@@H]2O[C@](C)([C@@H]1OC)N1C3=C(C=CC=C3)C3=C1C1=C(C4=C(C=CC=C4)N21)C1=C3CNC1=O
CTH	DB00114	cystathionase (cystathionine gamma-lyase)	nutraceutical	Pyridoxal Phosphate	CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O
CTH	DB00151	cystathionase (cystathionine gamma-lyase)	approved; nutraceutical	L-Cysteine	N[C@@H](CS)C(O)=O
CTH	DB02328	cystathionase (cystathionine gamma-lyase)	experimental	2-[(3-Hydroxy-2-Methyl-5-Phosphonooxymethyl-Pyridin-4-Ylmethyl)-Imino]-5-Phosphono-Pent-3-Enoic Acid	CC1=NC=C(COP(O)(O)=O)C(C\N=C(\C=C\CP(O)(O)=O)/C(O)=O)=C1O
CTH	DB03928	cystathionase (cystathionine gamma-lyase)	experimental	Carboxymethylthio-3-(3-Chlorophenyl)-1,2,4-Oxadiazol	OC(=O)CSC1=NC(=NO1)C1=CC=CC(Cl)=C1
CTH	DB04217	cystathionase (cystathionine gamma-lyase)	experimental	L-2-amino-3-butynoic acid	N[C@@H](C#C)C(O)=O
CTH	DB01008	cystathionase (cystathionine gamma-lyase)	approved; investigational	Busulfan	CS(=O)(=O)OCCCCOS(C)(=O)=O
CTNNB1	DB03904	catenin (cadherin-associated protein), beta 1, 88kDa	experimental	Urea	NC(N)=O
CTNNB1	DB00125	catenin (cadherin-associated protein), beta 1, 88kDa	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
CTNNB1	DB00435	catenin (cadherin-associated protein), beta 1, 88kDa	approved	Nitric Oxide	[N]=O
CTNNB1	DB00122	catenin (cadherin-associated protein), beta 1, 88kDa	approved; nutraceutical	Choline	C[N+](C)(C)CCO
CTNNB1	DB00482	catenin (cadherin-associated protein), beta 1, 88kDa	approved; investigational	Celecoxib	CC1=CC=C(C=C1)C1=CC(=NN1C1=CC=C(C=C1)S(N)(=O)=O)C(F)(F)F
CTPS1	DB00130	CTP synthase 1	approved; nutraceutical; investigational	L-Glutamine	N[C@@H](CCC(N)=O)C(O)=O
CTSA	DB03014	cathepsin A	experimental	Heme	CC1=C(CCC(O)=O)C2=CC3=[N+]4C(=CC5=C(C=C)C(C)=C6C=C7C(C=C)=C(C)C8=[N+]7[Fe@]4(N2C1=C8)N56)C(C)=C3CCC(O)=O
CTSA	DB07690	cathepsin A	experimental	(3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID	C[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C
CUBN	DB00200	cubilin (intrinsic factor-cobalamin receptor)	approved	Hydroxocobalamin	C([C@@H]1[C@]2(CCC(NC[C@H](OP(O[C@@H]3[C@H](O[C@@H]([C@@H]3O)N3C=[N]([Co+]456([N]7=C8C=C9[N]4=C(C(C)=C2N5[C@H]1[C@@]1([N]6=C(C(C)=C7[C@@](CC(N)=O)([C@@H]8CCC(N)=O)C)[C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)C)[C@H](C9(C)C)CCC(N)=O)O)C1=CC(=C(C=C31)C)C)CO)([O-])=O)C)=O)C)C(N)=O
CUBN	DB00136	cubilin (intrinsic factor-cobalamin receptor)	approved; nutraceutical	Calcitriol	C[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2C(CCC[C@]12C)=CC=C1C[C@@H](O)C[C@H](O)C1=C
DAO	DB02838	D-amino-acid oxidase	experimental	3,4-Dihydro-2h-Pyrrolium-5-Carboxylate	[O-]C(=O)C1=[NH+]CCC1
DAO	DB02988	D-amino-acid oxidase	experimental	Imino-Tryptophan	OC(=O)C(=N)CC1=CNC2=CC=CC=C12
DAO	DB03147	D-amino-acid oxidase	experimental	Flavin-Adenine Dinucleotide	CC1=CC2=C(C=C1C)N(C[C@H](O)[C@H](O)[C@H](O)CO[P@](O)(=O)O[P@@](O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC3=C1N=CN=C3N)C1=NC(=O)NC(=O)C1=N2
DAO	DB03225	D-amino-acid oxidase	experimental	D-Tryptophan	N[C@@H](Cc1cnc2ccccc12)C(O)=O
DAO	DB03531	D-amino-acid oxidase	experimental	Flavin-Adenine Dinucleotide-N5-Isobutyl Ketone	CC(C)C(=O)[N+]1=C2C(=O)NC(=O)N=C2N(C[C@@H](O)[C@@H](O)[C@H](O)CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@@H]2O[C@H]([C@H](O)[C@H]2O)N2C=NC3=C2N=CN=C3N)C2=CC(C)=C(C)C=C12
DAO	DB03793	D-amino-acid oxidase	experimental	Benzoic Acid	OC(=O)C1=CC=CC=C1
DAO	DB04166	D-amino-acid oxidase	experimental	2-Aminobenzoic Acid	NC1=CC=CC=C1C(O)=O
DAO	DB07979	D-amino-acid oxidase	experimental	(2E)-3-(3,4-DIHYDROXYPHENYL)-2-IMINOPROPANOIC ACID	OC(=O)C(=N)CC1=CC(O)=C(O)C=C1
DAO	DB00145	D-amino-acid oxidase	approved; nutraceutical	Glycine	NCC(O)=O
DAO	DB00160	D-amino-acid oxidase	approved; nutraceutical	L-Alanine	C[C@H](N)C(O)=O
DBH	DB00126	dopamine beta-hydroxylase (dopamine beta-monooxygenase)	approved; nutraceutical	Vitamin C	OC[C@H](O)[C@H]1OC(=O)C(O)=C1O
DBH	DB00822	dopamine beta-hydroxylase (dopamine beta-monooxygenase)	approved	Disulfiram	CCN(CC)C(=S)SSC(=S)N(CC)CC
DBH	DB00988	dopamine beta-hydroxylase (dopamine beta-monooxygenase)	approved	Dopamine	NCCC1=CC(O)=C(O)C=C1
DBH	DB00184	dopamine beta-hydroxylase (dopamine beta-monooxygenase)	approved	Nicotine	CN1CCCC1C1=CN=CC=C1
DBH	DB00135	dopamine beta-hydroxylase (dopamine beta-monooxygenase)	approved; nutraceutical	L-Tyrosine	N[C@@H](CC1=CC=C(O)C=C1)C(O)=O
DBH	DB00360	dopamine beta-hydroxylase (dopamine beta-monooxygenase)	approved; investigational	Tetrahydrobiopterin	CC(O)C(O)C1CNC2=C(N1)C(=O)N=C(N)N2
DBH	DB00368	dopamine beta-hydroxylase (dopamine beta-monooxygenase)	approved	Norepinephrine	NC[C@H](O)C1=CC(O)=C(O)C=C1
DBH	DB01235	dopamine beta-hydroxylase (dopamine beta-monooxygenase)	approved	Levodopa	N[C@@H](CC1=CC(O)=C(O)C=C1)C(O)=O
DBH	DB01156	dopamine beta-hydroxylase (dopamine beta-monooxygenase)	approved	Bupropion	CC(NC(C)(C)C)C(=O)C1=CC(Cl)=CC=C1
DCK	DB01073	deoxycytidine kinase	approved	Fludarabine	NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@@H]3O)C2=NC(F)=N1
DCK	DB02594	deoxycytidine kinase	experimental	2'-Deoxycytidine	NC1=NC(=O)N(C=C1)[C@H]1C[C@@H](O)[C@H](CO)O1
DCK	DB03431	deoxycytidine kinase	experimental	Adenosine-5'-Diphosphate	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](CO[P@](O)(=O)OP(O)(O)=O)[C@H](O)[C@H]1O
DCK	DB00709	deoxycytidine kinase	approved; investigational	Lamivudine	NC1=NC(=O)N(C=C1)[C@@H]1CS[C@H](CO)O1
DCK	DB00694	deoxycytidine kinase	approved	Daunorubicin	COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3O[C@H]3C[C@H](N)[C@H](O)[C@H](C)O3)C(C)=O)C(O)=C1C2=O
DCK	DB00773	deoxycytidine kinase	approved	Etoposide	COC1=CC(=CC(OC)=C1O)[C@H]1[C@@H]2[C@H](COC2=O)[C@H](O[C@@H]2O[C@@H]3CO[C@@H](C)O[C@H]3[C@H](O)[C@H]2O)C2=CC3=C(OCO3)C=C12
DCK	DB00619	deoxycytidine kinase	approved	Imatinib	CN1CCN(CC2=CC=C(C=C2)C(=O)NC2=CC(NC3=NC=CC(=N3)C3=CN=CC=C3)=C(C)C=C2)CC1
DCK	DB01204	deoxycytidine kinase	approved; investigational	Mitoxantrone	OCCNCCNC1=C2C(=O)C3=C(O)C=CC(O)=C3C(=O)C2=C(NCCNCCO)C=C1
DCK	DB00541	deoxycytidine kinase	approved; investigational	Vincristine	CC[C@]1(O)C[C@H]2CN(C1)CCC1=C(NC3=CC=CC=C13)[C@@](C2)(C(=O)OC)C1=C(OC)C=C2N(C=O)[C@@H]3[C@]4(CCN5CC=C[C@](CC)([C@@H]45)[C@@H](OC(C)=O)[C@]3(O)C(=O)OC)C2=C1
DCK	DB02745	deoxycytidine kinase	experimental	Uridine	OC[C@@H]1O[C@H]([C@H](O)[C@H]1O)N1C=CC(=O)NC1=O
DCK	DB00987	deoxycytidine kinase	approved; investigational	Cytarabine	NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O
DCK	DB00441	deoxycytidine kinase	approved	Gemcitabine	NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](CO)[C@@H](O)C1(F)F
DCK	DB00515	deoxycytidine kinase	approved	Cisplatin	N[Pt](N)(Cl)Cl
DCN	DB01006	decorin	approved; investigational	Letrozole	N#CC1=CC=C(C=C1)C(N1C=NC=N1)C1=CC=C(C=C1)C#N
DCP1B	DB00184	decapping mRNA 1B	approved	Nicotine	CN1CCCC1C1=CN=CC=C1
DCPS	DB01649	decapping enzyme, scavenger	experimental	7-Methyl-Gpppa	CN1C=[N+]([C@@H]2O[C@H](CO[P@](O)(=O)O[P@](O)(=O)O[P@](O)(=O)OC[C@H]3O[C@H]([C@H](O)[C@@H]3O)N3C=NC4=C(N)N=CN=C34)[C@@H](O)[C@H]2O)C2=C1C(=O)N=C(N)N2
DCPS	DB01960	decapping enzyme, scavenger	experimental	7n-Methyl-8-Hydroguanosine-5'-Diphosphate	CN1CN([C@@H]2O[C@@H](CO[P@](O)(=O)OP(O)(O)=O)[C@H](O)[C@H]2O)C2=C1C(=O)NC(N)=N2
DCPS	DB03593	decapping enzyme, scavenger	experimental	N7-Methyl-Guanosine-5'-Monophosphate	C[N+]1=CN([C@@H]2O[C@@H](COP(O)(O)=O)[C@H](O)[C@H]2O)C2=C1C(=O)NC(N)=N2
DCPS	DB03958	decapping enzyme, scavenger	experimental	Mrna Cap Analog N7-Methyl Gpppg	C[N+]1=CN([C@@H]2O[C@@H](CO[P@](O)(=O)O[P@](O)(=O)O[P@@](O)(=O)OC[C@@H]3O[C@H]([C@H](O)[C@H]3O)N3C=NC4=C3N=C(N)NC4=O)[C@H](O)[C@H]2O)C2=C1C(=O)NC(N)=N2
DCPS	DB07642	decapping enzyme, scavenger	experimental	5-{[1-(2-fluorobenzyl)piperidin-4-yl]methoxy}quinazoline-2,4-diamine	NC1=NC2=CC=CC(OCC3CCN(CC4=CC=CC=C4F)CC3)=C2C(N)=N1
DCPS	DB07643	decapping enzyme, scavenger	experimental	5-{[1-(2,3-dichlorobenzyl)piperidin-4-yl]methoxy}quinazoline-2,4-diamine	NC1=NC2=C(C(N)=N1)C(OCC1CCN(CC3=C(Cl)C(Cl)=CC=C3)CC1)=CC=C2
DCPS	DB07644	decapping enzyme, scavenger	experimental	5-[(1S)-1-(3-chlorophenyl)ethoxy]quinazoline-2,4-diamine	C[C@H](OC1=C2C(N)=NC(N)=NC2=CC=C1)C1=CC(Cl)=CC=C1
DCTD	DB04077	dCMP deaminase	experimental	Glycerol	OCC(O)CO
DCTD	DB00987	dCMP deaminase	approved; investigational	Cytarabine	NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O
DCTD	DB00130	dCMP deaminase	approved; nutraceutical; investigational	L-Glutamine	N[C@@H](CCC(N)=O)C(O)=O
DCTD	DB00441	dCMP deaminase	approved	Gemcitabine	NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](CO)[C@@H](O)C1(F)F
DCTD	DB01101	dCMP deaminase	approved; investigational	Capecitabine	CCCCCOC(=O)NC1=NC(=O)N(C=C1F)[C@@H]1O[C@H](C)[C@@H](O)[C@H]1O
DDC	DB00114	dopa decarboxylase (aromatic L-amino acid decarboxylase)	nutraceutical	Pyridoxal Phosphate	CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O
DDC	DB00190	dopa decarboxylase (aromatic L-amino acid decarboxylase)	approved	Carbidopa	C[C@@](CC1=CC(O)=C(O)C=C1)(NN)C(O)=O
DDC	DB00126	dopa decarboxylase (aromatic L-amino acid decarboxylase)	approved; nutraceutical	Vitamin C	OC[C@H](O)[C@H]1OC(=O)C(O)=C1O
DDC	DB00184	dopa decarboxylase (aromatic L-amino acid decarboxylase)	approved	Nicotine	CN1CCCC1C1=CN=CC=C1
DDC	DB01235	dopa decarboxylase (aromatic L-amino acid decarboxylase)	approved	Levodopa	N[C@@H](CC1=CC(O)=C(O)C=C1)C(O)=O
DDC	DB00988	dopa decarboxylase (aromatic L-amino acid decarboxylase)	approved	Dopamine	NCCC1=CC(O)=C(O)C=C1
DDC	DB00135	dopa decarboxylase (aromatic L-amino acid decarboxylase)	approved; nutraceutical	L-Tyrosine	N[C@@H](CC1=CC=C(O)C=C1)C(O)=O
DDC	DB00360	dopa decarboxylase (aromatic L-amino acid decarboxylase)	approved; investigational	Tetrahydrobiopterin	CC(O)C(O)C1CNC2=C(N1)C(=O)N=C(N)N2
DDC	DB00150	dopa decarboxylase (aromatic L-amino acid decarboxylase)	approved; nutraceutical	L-Tryptophan	N[C@@H](CC1=CNC2=CC=CC=C12)C(O)=O
DDC	DB01001	dopa decarboxylase (aromatic L-amino acid decarboxylase)	approved	Salbutamol	CC(C)(C)NCC(O)C1=CC(CO)=C(O)C=C1
DDX6	DB01694	DEAD (Asp-Glu-Ala-Asp) box helicase 6	experimental	D-tartaric acid	O[C@@H]([C@@H](O)C(O)=O)C(O)=O
DECR1	DB01907	2,4-dienoyl CoA reductase 1, mitochondrial	experimental	Nicotinamide-Adenine-Dinucleotide	NC(=O)C1=CC=C[N+](=C1)[C@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@@H]1O
DECR1	DB03461	2,4-dienoyl CoA reductase 1, mitochondrial	experimental	2'-Monophosphoadenosine 5'-Diphosphoribose	NC(=O)C1=CC=C[N+](=C1)[C@@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@@H]2O[C@H]([C@H](OP(O)(O)=O)[C@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@H]1O
DECR1	DB08604	2,4-dienoyl CoA reductase 1, mitochondrial	experimental	TRICLOSAN	OC1=C(OC2=C(Cl)C=C(Cl)C=C2)C=CC(Cl)=C1
DECR1	DB08605	2,4-dienoyl CoA reductase 1, mitochondrial	experimental	6-METHYL-2(PROPANE-1-SULFONYL)-2H-THIENO[3,2-D][1,2,3]DIAZABORININ-1-OL	CCCS(=O)(=O)N1N=CC2=C(C=C(C)S2)B1O
DGKA	DB00163	diacylglycerol kinase, alpha 80kDa	approved; nutraceutical	Vitamin E	CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCC2=C(O1)C(C)=C(C)C(O)=C2C
DGKD	DB00144	diacylglycerol kinase, delta 130kDa	approved; nutraceutical	Phosphatidylserine	CCCC(=O)O[C@H](COC(=O)CC)COP(O)(=O)OC[C@H](N)C(O)=O
DGKG	DB00144	diacylglycerol kinase, gamma 90kDa	approved; nutraceutical	Phosphatidylserine	CCCC(=O)O[C@H](COC(=O)CC)COP(O)(=O)OC[C@H](N)C(O)=O
DHCR7	DB00157	7-dehydrocholesterol reductase	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
DHFR	DB00157	dihydrofolate reductase	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
DHFR	DB00205	dihydrofolate reductase	approved	Pyrimethamine	CCC1=C(C(N)=NC(N)=N1)C1=CC=C(Cl)C=C1
DHFR	DB00440	dihydrofolate reductase	approved	Trimethoprim	COC1=CC(CC2=CN=C(N)N=C2N)=CC(OC)=C1OC
DHFR	DB00563	dihydrofolate reductase	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
DHFR	DB00642	dihydrofolate reductase	approved; investigational	Pemetrexed	NC1=NC(=O)C2=C(NC=C2CCC2=CC=C(C=C2)C(=O)N[C@H](CCC(O)=O)C(O)=O)N1
DHFR	DB01131	dihydrofolate reductase	approved	Proguanil	CC(C)\N=C(/N)N=C(N)NC1=CC=C(Cl)C=C1
DHFR	DB01157	dihydrofolate reductase	approved	Trimetrexate	COC1=CC(NCC2=C(C)C3=C(C=C2)N=C(N)N=C3N)=CC(OC)=C1OC
DHFR	DB02104	dihydrofolate reductase	experimental	2,4-Diamino-5-Methyl-6-[(3,4,5-Trimethoxy-N-Methylanilino)Methyl]Pyrido[2,3-D]Pyrimidine	COC1=CC(=CC(OC)=C1OC)N(C)CC1=C(C)C2=C(N)N=C(N)N=C2N=C1
DHFR	DB02427	dihydrofolate reductase	experimental	2,4-Diamino-6-[N-(2',5'-Dimethoxybenzyl)-N-Methylamino]Quinazoline	COC1=CC(CN(C)C2=CC=C3N=C(N)N=C(N)C3=C2)=C(OC)C=C1
DHFR	DB02559	dihydrofolate reductase	experimental	6-(Octahydro-1h-Indol-1-Ylmethyl)Decahydroquinazoline-2,4-Diamine	N[C@H]1N[C@@H](N)[C@@H]2C[C@@H](CN3CC[C@H]4CCCC[C@H]34)CC[C@@H]2N1
DHFR	DB02583	dihydrofolate reductase	experimental	N6-(2,5-Dimethoxy-Benzyl)-N6-Methyl-Pyrido[2,3-D]Pyrimidine-2,4,6-Triamine	COC1=CC(CN(C)C2=CC3=C(N=C2)N=C(N)N=C3N)=C(OC)C=C1
DHFR	DB02919	dihydrofolate reductase	experimental	2,4-Diamino-6-[N-(3',4',5'-Trimethoxybenzyl)-N-Methylamino]Pyrido[2,3-D]Pyrimidine	COC1=CC(CN(C)C2=CN=C3N=C(N)N=C(N)C3=C2)=CC(OC)=C1OC
DHFR	DB03060	dihydrofolate reductase	experimental	Sri-9662	COC1=CC(\C=C/C2=C(C)C3=C(N)N=C(N)N=C3N=C2)=C(OC)C=C1
DHFR	DB03125	dihydrofolate reductase	experimental	2,4-Diamino-5-(3,4,5-Trimethoxy-Benzyl)-Pyrimidin-1-Ium	COC1=CC(CC2=C[NH+]=C(N)N=C2N)=CC(OC)=C1OC
DHFR	DB03351	dihydrofolate reductase	experimental	Sri-9439	CC1=C(CNC2=CC=CC3=NC=CC=C23)C=NC2=NC(N)=NC(N)=C12
DHFR	DB03461	dihydrofolate reductase	experimental	2'-Monophosphoadenosine 5'-Diphosphoribose	NC(=O)C1=CC=C[N+](=C1)[C@@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@@H]2O[C@H]([C@H](OP(O)(O)=O)[C@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@H]1O
DHFR	DB03695	dihydrofolate reductase	experimental	6-(2,5-Dimethoxy-Benzyl)-5-Methyl-Pyrido[2,3-D]Pyrimidine-2,4-Diamine	COC1=CC(CC2=C(C)C3=C(N=C2)N=C(N)N=C3N)=C(OC)C=C1
DHFR	DB03886	dihydrofolate reductase	experimental	Biopterin	C[C@@H](O)[C@@H](O)C1=CN=C2N=C(N)NC(=O)C2=N1
DHFR	DB03987	dihydrofolate reductase	experimental	2,4-Diamino-6-[N-(3',5'-Dimethoxybenzyl)-N-Methylamino]Pyrido[2,3-D]Pyrimidine	COC1=CC(OC)=CC(CN(C)C2=CN=C3N=C(N)N=C(N)C3=C2)=C1
DHFR	DB07140	dihydrofolate reductase	experimental	5-[(3R)-3-(5-methoxybiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine	COC1=CC(=CC(=C1)[C@@H](C)C#CC1=C(C)N=C(N)N=C1N)C1=CC=CC=C1
DHFR	DB07141	dihydrofolate reductase	experimental	5-[(3R)-3-(5-methoxy-4'-methylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine	COC1=CC(=CC(=C1)[C@@H](C)C#CC1=C(C)N=C(N)N=C1N)C1=CC=C(C)C=C1
DHFR	DB07142	dihydrofolate reductase	experimental	5-[(3R)-3-(5-methoxy-3',5'-dimethylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine	COC1=CC(=CC(=C1)[C@@H](C)C#CC1=C(C)N=C(N)N=C1N)C1=CC(C)=CC(C)=C1
DHFR	DB07144	dihydrofolate reductase	experimental	5-[(3R)-3-(5-methoxy-2',6'-dimethylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine	COC1=CC(=CC(=C1)[C@@H](C)C#CC1=C(N)N=C(N)N=C1C)C1=C(C)C=CC=C1C
DHFR	DB08234	dihydrofolate reductase	experimental	5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]-6-ethylpyrimidine-2,4-diamine	CCC1=NC(N)=NC(N)=C1C#CCC1=CC(OC)=CC=C1OC
DHFR	DB08406	dihydrofolate reductase	experimental	[N-(2,4-DIAMINOPTERIDIN-6-YL)-METHYL]-DIBENZ[B,F]AZEPINE	NC1=NC2=C(N=C(CN3C4=CC=CC=C4C=CC4=CC=CC=C34)C=N2)C(N)=N1
DHFR	DB08448	dihydrofolate reductase	experimental	(4aS)-5-[(2,4-diaminopteridin-6-yl)methyl]-4a,5-dihydro-2H-dibenzo[b,f]azepin-8-ol	NC1=NC(N)=C2N=C(CN3[C@H]4C=CCC=C4C=CC4=CC(O)=CC=C34)C=NC2=N1
DHFR	DB08642	dihydrofolate reductase	experimental	(2R,6S)-6-{[methyl(3,4,5-trimethoxyphenyl)amino]methyl}-1,2,5,6,7,8-hexahydroquinazoline-2,4-diamine	COC1=CC(=CC(OC)=C1OC)N(C)C[C@H]1CCC2=C(C1)C(N)=N[C@H](N)N2
DHFR	DB01929	dihydrofolate reductase	experimental	5-Chloryl-2,4,6-Quinazolinetriamine	NC1=C(C2=C(N)N=C(N)N=C2C=C1)[Cl](=O)=O
DHFR	DB01958	dihydrofolate reductase	experimental	5-[4-Tert-Butylphenylsulfanyl]-2,4-Quinazolinediamine	CC(C)(C)C1=CC=C(SC2=CC=CC3=C2C(N)=NC(N)=N3)C=C1
DHFR	DB02001	dihydrofolate reductase	experimental	5-(4-Morpholin-4-Yl-Phenylsulfanyl)-2,4-Quinazolinediamine	NC1=NC2=C(C(N)=N1)C(SC1=CC=C(C=C1)N1CCOCC1)=CC=C2
DHFR	DB02402	dihydrofolate reductase	experimental	5-(4-Methoxyphenoxy)-2,4-Quinazolinediamine	COC1=CC=C(OC2=CC=CC3=NC(N)=NC(N)=C23)C=C1
DHFR	DB03814	dihydrofolate reductase	experimental	2-(N-Morpholino)-Ethanesulfonic Acid	[O-]S(=O)(=O)CC[NH+]1CCOCC1
DHFR	DB04163	dihydrofolate reductase	experimental	5-Phenylsulfanyl-2,4-Quinazolinediamine	NC1=NC2=C(C(N)=N1)C(SC1=CC=CC=C1)=CC=C2
DHFR	DB04306	dihydrofolate reductase	experimental	5-[(4-Methylphenyl)Sulfanyl]-2,4-Quinazolinediamine	CC1=CC=C(SC2=CC=CC3=C2C(N)=NC(N)=N3)C=C1
DHFR	DB02026	dihydrofolate reductase	experimental	Furo[2,3d]Pyrimidine Antifolate	CN(CC1=COC2=C1C(N)=NC(N)=N2)C1=CC=C(C=C1)C(=O)N[C@H](CCC(O)=O)C(O)=O
DHFR	DB02809	dihydrofolate reductase	experimental	Brodimoprim-4,6-Dicarboxylate	COC1=CC(CC2=C[NH+]=C(N)N=C2N)=CC(OCCC[C@@H](CCC([O-])=O)C([O-])=O)=C1Br
DHFR	DB04007	dihydrofolate reductase	experimental	Bromo-WR99210	CC1(C)N=C(N)N=C(N)N1OCCCOC1=CC=C(Br)C=C1
DHFR	DB02015	dihydrofolate reductase	experimental	Dihydrofolic Acid	NC1=NC(=O)C2=C(NCC(CNC3=CC=C(C=C3)C(=O)N[C@H](CCC(O)=O)C(O)=O)=N2)N1
DHFR	DB02363	dihydrofolate reductase	experimental	2'-Monophosphoadenosine-5'-Diphosphate	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](CO[P@](O)(=O)OP(O)(O)=O)[C@H](O)[C@H]1OP(O)(O)=O
DHFR	DB02718	dihydrofolate reductase	experimental	5-Formyl-6-Hydrofolic Acid	NC1=NC(=O)C2=C(N1)N=C[C@@H](CNC1=CC=C(C=C1)C(=O)N[C@H](CCC(O)=O)C(O)=O)N2C=O
DHFR	DB03625	dihydrofolate reductase	experimental	5,10-Dideazatetrahydrofolic Acid	NC1=NC(=O)C2=C(NC[C@@H](CCC3=CC=C(C=C3)C(=O)N[C@H](CCC(O)=O)C(O)=O)C2)N1
DHFR	DB03904	dihydrofolate reductase	experimental	Urea	NC(N)=O
DHFR	DB07262	dihydrofolate reductase	experimental	1-{[N-(1-IMINO-GUANIDINO-METHYL)]SULFANYLMETHYL}-3-TRIFLUOROMETHYL-BENZENE	NC(=N)NC(=N)SCC1=CC=CC(=C1)C(F)(F)F
DHFR	DB07938	dihydrofolate reductase	experimental	5-[[(2R)-2-cyclopropyl-7,8-dimethoxy-chroman-5-yl]methyl]pyrimidine-2,4-diamine	COC1=C(OC)C2=C(CC[C@@H](O2)C2CC2)C(CC2=CN=C(N)N=C2N)=C1
DHFR	DB08741	dihydrofolate reductase	experimental	5-[[(2R)-2-cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl]methyl]pyrimidine-2,4-diamine	COC1=CC(CC2=C(N)N=C(N)N=C2)=C2C=C[C@H](OC2=C1OC)C1CC1
DHFR	DB00515	dihydrofolate reductase	approved	Cisplatin	N[Pt](N)(Cl)Cl
DHFR	DB00531	dihydrofolate reductase	approved; investigational	Cyclophosphamide	ClCCN(CCCl)P1(=O)NCCCO1
DHFR	DB00970	dihydrofolate reductase	approved	Dactinomycin	CC(C)C1NC(=O)C(NC(=O)C2=C3N=C4C(OC3=C(C)C=C2)=C(C)C(=O)C(N)=C4C(=O)NC2C(C)OC(=O)C(C(C)C)N(C)C(=O)CN(C)C(=O)C3CCCN3C(=O)C(NC2=O)C(C)C)C(C)OC(=O)C(C(C)C)N(C)C(=O)CN(C)C(=O)C2CCCN2C1=O
DHFR	DB00997	dihydrofolate reductase	approved; investigational	Doxorubicin	COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3O[C@H]3C[C@H](N)[C@H](O)[C@H](C)O3)C(=O)CO)C(O)=C1C2=O
DHFR	DB00541	dihydrofolate reductase	approved; investigational	Vincristine	CC[C@]1(O)C[C@H]2CN(C1)CCC1=C(NC3=CC=CC=C13)[C@@](C2)(C(=O)OC)C1=C(OC)C=C2N(C=O)[C@@H]3[C@]4(CCN5CC=C[C@](CC)([C@@H]45)[C@@H](OC(C)=O)[C@]3(O)C(=O)OC)C2=C1
DHFR	DB00145	dihydrofolate reductase	approved; nutraceutical	Glycine	NCC(O)=O
DHFR	DB00133	dihydrofolate reductase	approved; nutraceutical	L-Serine	N[C@@H](CO)C(O)=O
DHFR	DB00158	dihydrofolate reductase	approved; nutraceutical	Folic Acid	NC1=NC(=O)C2=NC(CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)=CN=C2N1
DHFR	DB00544	dihydrofolate reductase	approved	Fluorouracil	FC1=CNC(=O)NC1=O
DHFR	DB01050	dihydrofolate reductase	approved	Ibuprofen	CC(C)CC1=CC=C(C=C1)C(C)C(O)=O
DHODH	DB01097	dihydroorotate dehydrogenase (quinone)	approved; investigational	Leflunomide	CC1=C(C=NO1)C(=O)NC1=CC=C(C=C1)C(F)(F)F
DHODH	DB01117	dihydroorotate dehydrogenase (quinone)	approved	Atovaquone	OC1=C([C@H]2CC[C@@H](CC2)C2=CC=C(Cl)C=C2)C(=O)C2=CC=CC=C2C1=O
DHODH	DB02262	dihydroorotate dehydrogenase (quinone)	experimental	Orotic Acid	OC(=O)C1=CC(=O)NC(=O)N1
DHODH	DB02613	dihydroorotate dehydrogenase (quinone)	experimental	Decylamine-N,N-Dimethyl-N-Oxide	CCCCCCCCCC[N+](C)(C)[O-]
DHODH	DB03247	dihydroorotate dehydrogenase (quinone)	experimental	Riboflavin Monophosphate	CC1=CC2=C(C=C1C)N(C[C@@H](O)[C@@H](O)[C@H](O)COP(O)(O)=O)C1=NC(=O)NC(=O)C1=N2
DHODH	DB03480	dihydroorotate dehydrogenase (quinone)	experimental	Brequinar Analog	CC1=C(N=C2C=CC(F)=CC2=C1C(O)=O)C1=CC=C(C=C1)C1=CC=CC=C1
DHODH	DB03523	dihydroorotate dehydrogenase (quinone)	experimental	6-Fluoro-2-(2'-Fluoro-1,1'-Biphenyl-4-Yl)-3-Methylquinoline-4-Carboxylic Acid	CC1=C(N=C2C=CC(F)=CC2=C1C(O)=O)C1=CC=C(C=C1)C1=CC=CC=C1F
DHODH	DB03805	dihydroorotate dehydrogenase (quinone)	experimental	Antiproliferative Agent A771726	C[C@@H](O)[C@@H](C#N)C(=O)NC1=CC=C(C=C1)C(F)(F)F
DHODH	DB04147	dihydroorotate dehydrogenase (quinone)	experimental	Lauryl Dimethylamine-N-Oxide	CCCCCCCCCCCC[N+](C)(C)[O-]
DHODH	DB04281	dihydroorotate dehydrogenase (quinone)	experimental	2-[4-(4-Chlorophenyl)Cyclohexylidene]-3,4-Dihydroxy-1(2h)-Naphthalenone	OC1=C(O)C(=C2CCC(CC2)C2=CC=C(Cl)C=C2)C(=O)C2=C1C=CC=C2
DHODH	DB04583	dihydroorotate dehydrogenase (quinone)	experimental	5-(AMINOCARBONYL)-1,1':4',1''-TERPHENYL-3-CARBOXYLICACID	NC(=O)C1=CC(=CC(=C1)C1=CC=C(C=C1)C1=CC=CC=C1)C(O)=O
DHODH	DB07443	dihydroorotate dehydrogenase (quinone)	experimental	(2Z)-N-biphenyl-4-yl-2-cyano-3-hydroxybut-2-enamide	C\C(O)=C(/C#N)C(=O)NC1=CC=C(C=C1)C1=CC=CC=C1
DHODH	DB07559	dihydroorotate dehydrogenase (quinone)	experimental	(2Z)-2-cyano-N-(2,2'-dichlorobiphenyl-4-yl)-3-hydroxybut-2-enamide	C\C(O)=C(/C#N)C(=O)NC1=CC(Cl)=C(C=C1)C1=CC=CC=C1Cl
DHODH	DB07561	dihydroorotate dehydrogenase (quinone)	experimental	(2Z)-2-cyano-N-(3'-ethoxybiphenyl-4-yl)-3-hydroxybut-2-enamide	CCOC1=CC(=CC=C1)C1=CC=C(NC(=O)C(\C#N)=C(\C)O)C=C1
DHODH	DB07646	dihydroorotate dehydrogenase (quinone)	experimental	UNDECYLAMINE-N,N-DIMETHYL-N-OXIDE	CCCCCCCCCCC[N+](C)(C)[O-]
DHODH	DB07975	dihydroorotate dehydrogenase (quinone)	experimental	2-({[3,5-DIFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)CYCLOPENT-1-ENE-1-CARBOXYLIC ACID	OC(=O)C1=C(CCC1)C(=O)NC1=C(F)C=C(C=C1F)C1=CC=CC(OC(F)(F)F)=C1
DHODH	DB07976	dihydroorotate dehydrogenase (quinone)	experimental	3-{[(3-FLUORO-3'-METHOXYBIPHENYL-4-YL)AMINO]CARBONYL}THIOPHENE-2-CARBOXYLIC ACID	COC1=CC=CC(=C1)C1=CC=C(NC(=O)C2=C(SC=C2)C(O)=O)C(F)=C1
DHODH	DB07977	dihydroorotate dehydrogenase (quinone)	experimental	3-({[3,5-DIFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)THIOPHENE-2-CARBOXYLIC ACID	OC(=O)C1=C(C=CS1)C(=O)NC1=C(F)C=C(C=C1F)C1=CC(OC(F)(F)F)=CC=C1
DHODH	DB07978	dihydroorotate dehydrogenase (quinone)	experimental	2-({[2,3,5,6-TETRAFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)CYCLOPENTA-1,3-DIENE-1-CARBOXYLIC ACID	OC(=O)C1=C(C=CC1)C(=O)NC1=C(F)C(F)=C(C(F)=C1F)C1=CC(OC(F)(F)F)=CC=C1
DHODH	DB08006	dihydroorotate dehydrogenase (quinone)	experimental	N-anthracen-2-yl-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-amine	CC1=NC2=NC=NN2C(NC2=CC3=CC4=CC=CC=C4C=C3C=C2)=C1
DHODH	DB08008	dihydroorotate dehydrogenase (quinone)	experimental	5-methyl-N-[4-(trifluoromethyl)phenyl][1,2,4]triazolo[1,5-a]pyrimidin-7-amine	CC1=NC2=NC=NN2C(NC2=CC=C(C=C2)C(F)(F)F)=C1
DHODH	DB08169	dihydroorotate dehydrogenase (quinone)	experimental	(2Z)-N-biphenyl-4-yl-2-cyano-3-cyclopropyl-3-hydroxyprop-2-enamide	O\C(C1CC1)=C(\C#N)C(=O)NC1=CC=C(C=C1)C1=CC=CC=C1
DHODH	DB08172	dihydroorotate dehydrogenase (quinone)	experimental	(2Z)-N-(3-chloro-2'-methoxybiphenyl-4-yl)-2-cyano-3-hydroxybut-2-enamide	COC1=CC=CC=C1C1=CC(Cl)=C(NC(=O)C(\C#N)=C(\C)O)C=C1
DHODH	DB08249	dihydroorotate dehydrogenase (quinone)	experimental	3,6,9,12,15-PENTAOXATRICOSAN-1-OL	CCCCCCCCOCCOCCOCCOCCOCCO
DHODH	DB00130	dihydroorotate dehydrogenase (quinone)	approved; nutraceutical; investigational	L-Glutamine	N[C@@H](CCC(N)=O)C(O)=O
DHPS	DB01907	deoxyhypusine synthase	experimental	Nicotinamide-Adenine-Dinucleotide	NC(=O)C1=CC=C[N+](=C1)[C@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@@H]1O
DHPS	DB03639	deoxyhypusine synthase	experimental	1-Guanidinium-7-Aminoheptane	NCCCCCCCNC(N)N
DHPS	DB01033	deoxyhypusine synthase	approved	Mercaptopurine	S=C1N=CNC2=C1NC=N2
DHPS	DB00563	deoxyhypusine synthase	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
DHRS3	DB00162	dehydrogenase/reductase (SDR family) member 3	approved; nutraceutical	Vitamin A	CC(=CCO)C=CC=C(C)C=CC1=C(C)CCCC1(C)C
DHRS4	DB00162	dehydrogenase/reductase (SDR family) member 4	approved; nutraceutical	Vitamin A	CC(=CCO)C=CC=C(C)C=CC1=C(C)CCCC1(C)C
DHRS4L2	DB01907	dehydrogenase/reductase (SDR family) member 4 like 2	experimental	Nicotinamide-Adenine-Dinucleotide	NC(=O)C1=CC=C[N+](=C1)[C@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@@H]1O
DHRS4L2	DB04200	dehydrogenase/reductase (SDR family) member 4 like 2	experimental	Matairesinol	COC1=CC(C[C@H]2COC(=O)[C@@H]2CC2=CC=C(O)C(OC)=C2)=CC=C1O
DIO1	DB00451	deiodinase, iodothyronine, type I	approved	Levothyroxine	N[C@@H](CC1=CC(I)=C(OC2=CC(I)=C(O)C(I)=C2)C(I)=C1)C(O)=O
DIO2	DB00451	deiodinase, iodothyronine, type II	approved	Levothyroxine	N[C@@H](CC1=CC(I)=C(OC2=CC(I)=C(O)C(I)=C2)C(I)=C1)C(O)=O
DIO3	DB00451	deiodinase, iodothyronine, type III	approved	Levothyroxine	N[C@@H](CC1=CC(I)=C(OC2=CC(I)=C(O)C(I)=C2)C(I)=C1)C(O)=O
DLAT	DB00157	dihydrolipoamide S-acetyltransferase	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
DLAT	DB03758	dihydrolipoamide S-acetyltransferase	experimental	Radicicol	C[C@@H]1C[C@H]2O[C@@H]2CCCCC(=O)C[C@H]2[C@H](Cl)C(=O)CC(=O)[C@H]2C(=O)O1
DLAT	DB03760	dihydrolipoamide S-acetyltransferase	experimental	Dihydrolipoic Acid	OC(=O)CCCC[C@@H](S)CCS
DLD	DB00157	dihydrolipoamide dehydrogenase	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
DLD	DB01907	dihydrolipoamide dehydrogenase	experimental	Nicotinamide-Adenine-Dinucleotide	NC(=O)C1=CC=C[N+](=C1)[C@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@@H]1O
DLD	DB03147	dihydrolipoamide dehydrogenase	experimental	Flavin-Adenine Dinucleotide	CC1=CC2=C(C=C1C)N(C[C@H](O)[C@H](O)[C@H](O)CO[P@](O)(=O)O[P@@](O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC3=C1N=CN=C3N)C1=NC(=O)NC(=O)C1=N2
DNMT1	DB00928	DNA (cytosine-5-)-methyltransferase 1	approved; investigational	Azacitidine	NC1=NC(=O)N(C=N1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
DNMT1	DB01035	DNA (cytosine-5-)-methyltransferase 1	approved	Procainamide	CCN(CC)CCNC(=O)C1=CC=C(N)C=C1
DNMT1	DB01099	DNA (cytosine-5-)-methyltransferase 1	approved	Flucytosine	NC1=C(F)C=NC(=O)N1
DNMT1	DB01262	DNA (cytosine-5-)-methyltransferase 1	approved; investigational	Decitabine	NC1=NC(=O)N(C=N1)[C@H]1C[C@H](O)[C@@H](CO)O1
DPP4	DB01076	dipeptidyl-peptidase 4	approved	Atorvastatin	CC(C)C1=C(C(=O)NC2=CC=CC=C2)C(=C(N1CC[C@@H](O)C[C@@H](O)CC(O)=O)C1=CC=C(F)C=C1)C1=CC=CC=C1
DPP4	DB01261	dipeptidyl-peptidase 4	approved; investigational	Sitagliptin	N[C@@H](CC(=O)N1CCN2C(C1)=NN=C2C(F)(F)F)CC1=CC(F)=C(F)C=C1F
DPP4	DB01884	dipeptidyl-peptidase 4	experimental	2-Amino-3-Methyl-1-Pyrrolidin-1-Yl-Butan-1-One	CC(C)[C@H](N)C(=O)N1CCCC1
DPP4	DB02004	dipeptidyl-peptidase 4	experimental	5-(Aminomethyl)-6-(2,4-Dichlorophenyl)-2-(3,5-Dimethoxyphenyl)Pyrimidin-4-Amine	COC1=CC(=CC(OC)=C1)C1=NC(=C(CN)C(N)=N1)C1=CC=C(Cl)C=C1Cl
DPP4	DB02944	dipeptidyl-peptidase 4	experimental	Alpha-D-Mannose	OC[C@@H]1O[C@H](O)[C@@H](O)[C@H](O)[C@H]1O
DPP4	DB03253	dipeptidyl-peptidase 4	experimental	(2s)-Pyrrolidin-2-Ylmethylamine	NC[C@@H]1CCCN1
DPP4	DB03660	dipeptidyl-peptidase 4	experimental	Iodo-Phenylalanine	N[C@@H](CC1=CC=C(I)C=C1)C(O)=O
DPP4	DB04491	dipeptidyl-peptidase 4	experimental	Diisopropylphosphono Group	CC(C)OP(=O)OC(C)C
DPP4	DB04577	dipeptidyl-peptidase 4	experimental	1-(1-phenylcyclopentyl)methylamine	NCC1(CCCC1)C1=CC=CC=C1
DPP4	DB04578	dipeptidyl-peptidase 4	experimental	(S)-2-[(R)-3-amino-4-(2-fluorophenyl)butyryl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide	N[C@@H](CC(=O)N1CC2=CC=CC=C2C[C@H]1C(N)=O)CC1=CC=CC=C1F
DPP4	DB04876	dipeptidyl-peptidase 4	approved; investigational	Vildagliptin	OC12CC3CC(C1)CC(C3)(C2)NCC(=O)N1CCC[C@H]1C#N
DPP4	DB06335	dipeptidyl-peptidase 4	approved; investigational	Saxagliptin	N[C@H](C(=O)N1[C@H]2C[C@H]2C[C@H]1C#N)C12CC3CC(CC(O)(C3)C1)C2
DPP4	DB06880	dipeptidyl-peptidase 4	experimental	(1S)-2-[(2S,5R)-2-(AMINOMETHYL)-5-PROP-1-YN-1-YLPYRROLIDIN-1-YL]-1-CYCLOPENTYL-2-OXOETHANAMINE	CC#C[C@H]1CC[C@@H](CN)N1C(=O)[C@@H](N)C1CCCC1
DPP4	DB06939	dipeptidyl-peptidase 4	experimental	N-(TRANS-4-{(1S,2S)-2-AMINO-3-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-1-METHYL-3-OXOPROPYL}CYCLOHEXYL)-N-METHYLACETAMIDE	C[C@H]([C@H](N)C(=O)N1CC[C@H](F)C1)[C@H]1CC[C@@H](CC1)N(C)C(C)=O
DPP4	DB06993	dipeptidyl-peptidase 4	experimental	(2S,3S)-4-cyclopropyl-3-{(3R,5R)-3-[2-fluoro-4-(methylsulfonyl)phenyl]-1,2,4-oxadiazolidin-5-yl}-1-[(3S)-3-fluoropyrrolidin-1-yl]-1-oxobutan-2-amine	CS(=O)(=O)C1=CC=C([C@H]2NO[C@@H](N2)[C@@H](CC2CC2)[C@H](N)C(=O)N2CC[C@H](F)C2)C(F)=C1
DPP4	DB06994	dipeptidyl-peptidase 4	experimental	(2S,3S)-3-{3-[2-chloro-4-(methylsulfonyl)phenyl]-1,2,4-oxadiazol-5-yl}-1-cyclopentylidene-4-cyclopropyl-1-fluorobutan-2-amine	CS(=O)(=O)C1=CC=C(C2=NOC(=N2)[C@@H](CC2CC2)[C@H](N)C(F)=C2CCCC2)C(Cl)=C1
DPP4	DB07015	dipeptidyl-peptidase 4	experimental	(3R,4R)-4-(pyrrolidin-1-ylcarbonyl)-1-(quinoxalin-2-ylcarbonyl)pyrrolidin-3-amine	N[C@H]1CN(C[C@H]1C(=O)N1CCCC1)C(=O)C1=CN=C2C=CC=CC2=N1
DPP4	DB07021	dipeptidyl-peptidase 4	experimental	(7R,8R)-8-(2,4,5-trifluorophenyl)-6,7,8,9-tetrahydroimidazo[1,2-a:4,5-c']dipyridin-7-amine	N[C@H]1CN2C(C[C@@H]1C1=CC(F)=C(F)C=C1F)=NC1=C2C=CN=C1
DPP4	DB07067	dipeptidyl-peptidase 4	experimental	(2S,3S)-3-{3-[4-(METHYLSULFONYL)PHENYL]-1,2,4-OXADIAZOL-5-YL}-1-OXO-1-PYRROLIDIN-1-YLBUTAN-2-AMINE	C[C@@H]([C@H](N)C(=O)N1CCCC1)C1=NC(=NO1)C1=CC=C(C=C1)S(C)(=O)=O
DPP4	DB07072	dipeptidyl-peptidase 4	experimental	(1S,2R,5S)-5-[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]-2-(2,4,5-TRIFLUOROPHENYL)CYCLOHEXANAMINE	N[C@H]1C[C@H](CC[C@@H]1C1=C(F)C=C(F)C(F)=C1)N1CCN2C(C1)=NN=C2C(F)(F)F
DPP4	DB07081	dipeptidyl-peptidase 4	experimental	(2R)-4-[(8R)-8-METHYL-2-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[1,5-A]PYRAZIN-7(8H)-YL]-4-OXO-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-AMINE	C[C@H]1N(CCN2N=C(N=C12)C(F)(F)F)C(=O)C[C@H](N)CC1=C(F)C=C(F)C(F)=C1
DPP4	DB07092	dipeptidyl-peptidase 4	experimental	(2S,3S)-3-AMINO-4-(3,3-DIFLUOROPYRROLIDIN-1-YL)-N,N-DIMETHYL-4-OXO-2-(TRANS-4-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-6-YLCYCLOHEXYL)BUTANAMIDE	CN(C)C(=O)[C@H]([C@H](N)C(=O)N1CCC(F)(F)C1)[C@H]1CC[C@@H](CC1)C1=CN2N=CN=C2C=C1
DPP4	DB07135	dipeptidyl-peptidase 4	experimental	(2S,3S)-3-AMINO-4-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-N,N-DIMETHYL-4-OXO-2-(TRANS-4-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-5-YLCYCLOHEXYL)BUTANAMIDE	CN(C)C(=O)[C@H]([C@H](N)C(=O)N1CC[C@H](F)C1)[C@H]1CC[C@@H](CC1)C1=CC=CC2=NC=NN12
DPP4	DB07154	dipeptidyl-peptidase 4	experimental	(3R)-4-[(3R)-3-AMINO-4-(2,4,5-TRIFLUOROPHENYL)BUTANOYL]-3-METHYL-1,4-DIAZEPAN-2-ONE	C[C@H]1N(CCCNC1=O)C(=O)C[C@H](N)CC1=C(F)C=C(F)C(F)=C1
DPP4	DB07181	dipeptidyl-peptidase 4	experimental	4'-[(1R)-1-amino-2-(2,5-difluorophenyl)ethyl]biphenyl-3-carboxamide	N[C@H](CC1=CC(F)=CC=C1F)C1=CC=C(C=C1)C1=CC=CC(=C1)C(N)=O
DPP4	DB07193	dipeptidyl-peptidase 4	experimental	(2R,3R)-7-(methylsulfonyl)-3-(2,4,5-trifluorophenyl)-1,2,3,4-tetrahydropyrido[1,2-a]benzimidazol-2-amine	CS(=O)(=O)C1=CC=C2N3C[C@H](N)[C@H](CC3=NC2=C1)C1=C(F)C=C(F)C(F)=C1
DPP4	DB07239	dipeptidyl-peptidase 4	experimental	7-(aminomethyl)-6-(2-chlorophenyl)-1-methyl-1H-benzimidazole-5-carbonitrile	CN1C=NC2=CC(C#N)=C(C(CN)=C12)C1=C(Cl)C=CC=C1
DPP4	DB07271	dipeptidyl-peptidase 4	experimental	(3R)-4-[(3R)-3-AMINO-4-(2,4,5-TRIFLUOROPHENYL)BUTANOYL]-3-(2,2,2-TRIFLUOROETHYL)-1,4-DIAZEPAN-2-ONE	N[C@@H](CC(=O)N1CCCNC(=O)[C@H]1CC(F)(F)F)CC1=C(F)C=C(F)C(F)=C1
DPP4	DB07328	dipeptidyl-peptidase 4	experimental	METHYL 4-{[({[(2R,5S)-5-{[(2S)-2-(AMINOMETHYL)PYRROLIDIN-1-YL]CARBONYL}PYRROLIDIN-2-YL]METHYL}AMINO)CARBONYL]AMINO}BENZOATE	COC(=O)C1=CC=C(NC(=O)NC[C@H]2CC[C@H](N2)C(=O)N2CCC[C@H]2CN)C=C1
DPP4	DB07356	dipeptidyl-peptidase 4	experimental	(1S)-2-[(2S,5R)-2-(AMINOMETHYL)-5-ETHYNYLPYRROLIDIN-1-YL]-1-CYCLOPENTYL-2-OXOETHANAMINE	NC[C@@H]1CC[C@H](C#C)N1C(=O)[C@@H](N)C1CCCC1
DPP4	DB07412	dipeptidyl-peptidase 4	experimental	1-biphenyl-2-ylmethanamine	NCC1=C(C=CC=C1)C1=CC=CC=C1
DPP4	DB07465	dipeptidyl-peptidase 4	experimental	(1S,3S,5S)-2-{(2S)-2-amino-2-[(1R,3S,5R,7S)-3-hydroxytricyclo[3.3.1.1~3,7~]dec-1-yl]acetyl}-2-azabicyclo[3.1.0]hexane-3-carbonitrile	N[C@H](C(=O)N1[C@H]2C[C@H]2C[C@H]1C#N)[C@]12C[C@H]3C[C@H](C[C@](O)(C3)C1)C2
DPP4	DB07482	dipeptidyl-peptidase 4	experimental	(2R)-N-[(2R)-2-(DIHYDROXYBORYL)-1-L-PROLYLPYRROLIDIN-2-YL]-N-[(5R)-5-(DIHYDROXYBORYL)-1-L-PROLYLPYRROLIDIN-2-YL]-L-PROLINAMIDE	OB(O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1
DPP4	DB07666	dipeptidyl-peptidase 4	experimental	(3R,4S)-1-{6-[3-(METHYLSULFONYL)PHENYL]PYRIMIDIN-4-YL}-4-(2,4,5-TRIFLUOROPHENYL)PYRROLIDIN-3-AMINE	CS(=O)(=O)C1=CC=CC(=C1)C1=NC=NC(=C1)N1C[C@H](N)[C@H](C1)C1=CC(F)=C(F)C=C1F
DPP4	DB07779	dipeptidyl-peptidase 4	experimental	N-({(2S)-1-[(3R)-3-AMINO-4-(2-FLUOROPHENYL)BUTANOYL]PYRROLIDIN-2-YL}METHYL)BENZAMIDE	N[C@@H](CC(=O)N1CCC[C@H]1CNC(=O)C1=CC=CC=C1)CC1=C(F)C=CC=C1
DPP4	DB07830	dipeptidyl-peptidase 4	experimental	(4R,5R)-5-AMINO-1-[2-(1,3-BENZODIOXOL-5-YL)ETHYL]-4-(2,4,5-TRIFLUOROPHENYL)PIPERIDIN-2-ONE	N[C@H]1CN(CCC2=CC=C3OCOC3=C2)C(=O)C[C@@H]1C1=CC(F)=C(F)C=C1F
DPP4	DB07851	dipeptidyl-peptidase 4	experimental	(3R,4S)-1-(3,4-DIMETHOXYPHENYL)-3-(3-METHYLPHENYL)PIPERIDIN-4-AMINE	COC1=C(OC)C=C(C=C1)N1CC[C@H](N)[C@@H](C1)C1=CC(C)=CC=C1
DPP4	DB08024	dipeptidyl-peptidase 4	experimental	1-[2-(S)-AMINO-3-BIPHENYL-4-YL-PROPIONYL]-PYRROLIDINE-2-(S)-CARBONITRILE	NC[C@@H]1CCCN1C(=O)[C@@H](N)CC1=CC=C(C=C1)C1=CC=CC=C1
DPP4	DB08044	dipeptidyl-peptidase 4	experimental	(1S,6R)-3-{[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]CARBONYL}-6-(2,4,5-TRIFLUOROPHENYL)CYCLOHEX-3-EN-1-AMINE	N[C@H]1CC(=CC[C@@H]1C1=CC(F)=C(F)C=C1F)C(=O)N1CCN2C(C1)=NN=C2C(F)(F)F
DPP4	DB08051	dipeptidyl-peptidase 4	experimental	(2R)-4-(2-BENZOYL-1,2-DIAZEPAN-1-YL)-4-OXO-1-(2,4,5-TRIFLUOROPHENYL)BUTAN-2-AMINE	N[C@@H](CC(=O)N1CCCCCN1C(=O)C1=CC=CC=C1)CC1=C(F)C=C(F)C(F)=C1
DPP4	DB08164	dipeptidyl-peptidase 4	experimental	(3R,4R)-1-{6-[3-(METHYLSULFONYL)PHENYL]PYRIMIDIN-4-YL}-4-(2,4,5-TRIFLUOROPHENYL)PIPERIDIN-3-AMINE	CS(=O)(=O)C1=CC(=CC=C1)C1=CC(=NC=N1)N1CC[C@@H]([C@@H](N)C1)C1=CC(F)=C(F)C=C1F
DPP4	DB08382	dipeptidyl-peptidase 4	experimental	2-(4-{(3S,5S)-5-[(3,3-difluoropyrrolidin-1-yl)carbonyl]pyrrolidin-3-yl}piperazin-1-yl)pyrimidine	FC1(F)CCN(C1)C(=O)[C@@H]1C[C@@H](CN1)N1CCN(CC1)C1=NC=CC=N1
DPP4	DB08429	dipeptidyl-peptidase 4	experimental	N-({(2S)-1-[(3R)-3-amino-4-(3-chlorophenyl)butanoyl]pyrrolidin-2-yl}methyl)-3-(methylsulfonyl)benzamide	CS(=O)(=O)C1=CC(=CC=C1)C(=O)NC[C@@H]1CCCN1C(=O)C[C@H](N)CC1=CC(Cl)=CC=C1
DPP4	DB08445	dipeptidyl-peptidase 4	experimental	(3R,4S)-1-[6-(6-METHOXYPYRIDIN-3-YL)PYRIMIDIN-4-YL]-4-(2,4,5-TRIFLUOROPHENYL)PYRROLIDIN-3-AMINE	COC1=CC=C(C=N1)C1=NC=NC(=C1)N1C[C@H](N)[C@H](C1)C1=C(F)C=C(F)C(F)=C1
DPP4	DB08504	dipeptidyl-peptidase 4	experimental	6-(4-{(1S,2S)-2-AMINO-1-[(DIMETHYLAMINO)CARBONYL]-3-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-3-OXOPROPYL}PHENYL)-1H-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-4-IUM	CN(C)C(=O)[C@H]([C@H](N)C(=O)N1CC[C@H](F)C1)C1=CC=C(C=C1)C1=CN2N=CN=C2C=C1
DPP4	DB08530	dipeptidyl-peptidase 4	experimental	7-BENZYL-1,3-DIMETHYL-8-PIPERAZIN-1-YL-3,7-DIHYDRO-PURINE-2,6-DIONE	CN1C2=C(N(CC3=CC=CC=C3)C(=N2)N2CC[NH2+]CC2)C(=O)N(C)C1=O
DPP4	DB08588	dipeptidyl-peptidase 4	experimental	2-({2-[(3R)-3-AMINOPIPERIDIN-1-YL]-4-OXOQUINAZOLIN-3(4H)-YL}METHYL)BENZONITRILE	N[C@@H]1CCCN(C1)C1=NC2=C(C=CC=C2)C(=O)N1CC1=C(C=CC=C1)C#N
DPP4	DB08672	dipeptidyl-peptidase 4	experimental	4-[(3R)-3-{[2-(4-FLUOROPHENYL)-2-OXOETHYL]AMINO}BUTYL]BENZAMIDE	C[C@H](CCC1=CC=C(C=C1)C(N)=O)NCC(=O)C1=CC=C(F)C=C1
DPP4	DB08743	dipeptidyl-peptidase 4	experimental	2-({8-[(3R)-3-AMINOPIPERIDIN-1-YL]-1,3-DIMETHYL-2,6-DIOXO-1,2,3,6-TETRAHYDRO-7H-PURIN-7-YL}METHYL)BENZONITRILE	CN1C2=C(N(CC3=CC=CC=C3C#N)C(=N2)N2CCC[C@@H](N)C2)C(=O)N(C)C1=O
DPYD	DB02303	dihydropyrimidine dehydrogenase	experimental	(5s)-5-Iododihydro-2,4(1h,3h)-Pyrimidinedione	I[C@@H]1CNC(=O)NC1=O
DPYD	DB02338	dihydropyrimidine dehydrogenase	experimental	Nadph Dihydro-Nicotinamide-Adenine-Dinucleotidephosphate	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@@H](CO[P@](O)(=O)O[P@@](O)(=O)OC[C@@H]2O[C@H]([C@H](OP(O)(O)=O)[C@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@H]1O
DPYD	DB03048	dihydropyrimidine dehydrogenase	experimental	6-Carboxymethyluracil	OC(=O)CC1=CC(=O)NC(=O)N1
DPYD	DB03147	dihydropyrimidine dehydrogenase	experimental	Flavin-Adenine Dinucleotide	CC1=CC2=C(C=C1C)N(C[C@H](O)[C@H](O)[C@H](O)CO[P@](O)(=O)O[P@@](O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC3=C1N=CN=C3N)C1=NC(=O)NC(=O)C1=N2
DPYD	DB03247	dihydropyrimidine dehydrogenase	experimental	Riboflavin Monophosphate	CC1=CC2=C(C=C1C)N(C[C@@H](O)[C@@H](O)[C@H](O)COP(O)(O)=O)C1=NC(=O)NC(=O)C1=N2
DPYD	DB03419	dihydropyrimidine dehydrogenase	experimental	Uracil	O=C1NC=CC(=O)N1
DPYD	DB03554	dihydropyrimidine dehydrogenase	experimental	5-Iodouracil	IC1=CNC(=O)NC1=O
DPYD	DB01248	dihydropyrimidine dehydrogenase	approved; investigational	Docetaxel	CC(=O)O[C@@]12CO[C@@H]1C[C@H](O)[C@]1(C)[C@@H]2[C@H](OC(=O)C2=CC=CC=C2)[C@]2(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C3=CC=CC=C3)C(C)=C([C@@H](O)C1=O)C2(C)C
DPYD	DB00515	dihydropyrimidine dehydrogenase	approved	Cisplatin	N[Pt](N)(Cl)Cl
DPYD	DB00650	dihydropyrimidine dehydrogenase	approved	Leucovorin	NC1=NC(=O)C2=C(NCC(CNC3=CC=C(C=C3)C(=O)N[C@H](CCC(O)=O)C(O)=O)N2C=O)N1
DPYD	DB00526	dihydropyrimidine dehydrogenase	approved; investigational	Oxaliplatin	O=C1O[Pt]2(N[C@@H]3CCCC[C@H]3N2)OC1=O
DPYD	DB00293	dihydropyrimidine dehydrogenase	approved; investigational	Raltitrexed	CN(CC1=CC2=C(NC(C)=NC2=O)C=C1)C1=CC=C(S1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
DPYD	DB00563	dihydropyrimidine dehydrogenase	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
DPYD	DB01101	dihydropyrimidine dehydrogenase	approved; investigational	Capecitabine	CCCCCOC(=O)NC1=NC(=O)N(C=C1F)[C@@H]1O[C@H](C)[C@@H](O)[C@H]1O
DPYD	DB00762	dihydropyrimidine dehydrogenase	approved; investigational	Irinotecan	CCC1=C2CN3C(=CC4=C(COC(=O)[C@]4(O)CC)C3=O)C2=NC2=C1C=C(OC(=O)N1CCC(CC1)N1CCCCC1)C=C2
DPYD	DB01033	dihydropyrimidine dehydrogenase	approved	Mercaptopurine	S=C1N=CNC2=C1NC=N2
DPYD	DB00544	dihydropyrimidine dehydrogenase	approved	Fluorouracil	FC1=CNC(=O)NC1=O
DPYD	DB01143	dihydropyrimidine dehydrogenase	approved; investigational	Amifostine	NCCCNCCSP(O)(O)=O
DPYD	DB00958	dihydropyrimidine dehydrogenase	approved	Carboplatin	N.N.O=C1O[Pt]OC(=O)C11CCC1
DPYD	DB01229	dihydropyrimidine dehydrogenase	approved	Paclitaxel	CC(=O)O[C@@H]1C2=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)C3=CC=CC=C3)[C@@H]3[C@@]4(CO[C@@H]4C[C@H](O)[C@@]3(C)C1=O)OC(C)=O)C2(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)C1=CC=CC=C1)C1=CC=CC=C1
DPYS	DB00544	dihydropyrimidinase	approved	Fluorouracil	FC1=CNC(=O)NC1=O
DTYMK	DB00130	deoxythymidylate kinase (thymidylate kinase)	approved; nutraceutical; investigational	L-Glutamine	N[C@@H](CCC(N)=O)C(O)=O
DTYMK	DB00495	deoxythymidylate kinase (thymidylate kinase)	approved	Zidovudine	CC1=CN([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2)C(=O)NC1=O
DUT	DB03413	deoxyuridine triphosphatase	experimental	Deoxyuridine-5'-Diphosphate	O[C@@H]1C[C@@H](O[C@H]1CO[P@](O)(=O)OP(O)(O)=O)N1C=CC(=O)NC1=O
DUT	DB04685	deoxyuridine triphosphatase	experimental	1-{(2S,5S)-4-FLUORO-5-[(TRITYLOXY)METHYL]TETRAHYDROFURAN-2-YL}PYRIMIDINE-2,4(1H,3H)-DIONE	F[C@H]1C[C@@H](O[C@@H]1COC(C1=CC=CC=C1)(C1=CC=CC=C1)C1=CC=CC=C1)N1C=CC(=O)NC1=O
DUT	DB00544	deoxyuridine triphosphatase	approved	Fluorouracil	FC1=CNC(=O)NC1=O
EARS2	DB00142	glutamyl-tRNA synthetase 2, mitochondrial	approved; nutraceutical	L-Glutamic Acid	N[C@@H](CCC(O)=O)C(O)=O
EARS2	DB00145	glutamyl-tRNA synthetase 2, mitochondrial	approved; nutraceutical	Glycine	NCC(O)=O
EARS2	DB00160	glutamyl-tRNA synthetase 2, mitochondrial	approved; nutraceutical	L-Alanine	C[C@H](N)C(O)=O
EARS2	DB00125	glutamyl-tRNA synthetase 2, mitochondrial	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
EARS2	DB00151	glutamyl-tRNA synthetase 2, mitochondrial	approved; nutraceutical	L-Cysteine	N[C@@H](CS)C(O)=O
EARS2	DB00130	glutamyl-tRNA synthetase 2, mitochondrial	approved; nutraceutical; investigational	L-Glutamine	N[C@@H](CCC(N)=O)C(O)=O
EARS2	DB00117	glutamyl-tRNA synthetase 2, mitochondrial	approved; nutraceutical	L-Histidine	N[C@@H](CC1=CN=CN1)C(O)=O
EARS2	DB00149	glutamyl-tRNA synthetase 2, mitochondrial	approved; nutraceutical	L-Leucine	CC(C)CC(N)C(O)=O
EARS2	DB00123	glutamyl-tRNA synthetase 2, mitochondrial	approved; nutraceutical	L-Lysine	NCCCC[C@H](N)C(O)=O
EARS2	DB00134	glutamyl-tRNA synthetase 2, mitochondrial	approved; nutraceutical	L-Methionine	CSCC[C@H](N)C(O)=O
EARS2	DB00120	glutamyl-tRNA synthetase 2, mitochondrial	approved; nutraceutical	L-Phenylalanine	N[C@@H](CC1=CC=CC=C1)C(O)=O
EARS2	DB00133	glutamyl-tRNA synthetase 2, mitochondrial	approved; nutraceutical	L-Serine	N[C@@H](CO)C(O)=O
EARS2	DB00156	glutamyl-tRNA synthetase 2, mitochondrial	approved; nutraceutical	L-Threonine	C[C@@H](O)[C@H](N)C(O)=O
EARS2	DB00150	glutamyl-tRNA synthetase 2, mitochondrial	approved; nutraceutical	L-Tryptophan	N[C@@H](CC1=CNC2=CC=CC=C12)C(O)=O
EARS2	DB00135	glutamyl-tRNA synthetase 2, mitochondrial	approved; nutraceutical	L-Tyrosine	N[C@@H](CC1=CC=C(O)C=C1)C(O)=O
EARS2	DB00161	glutamyl-tRNA synthetase 2, mitochondrial	approved; nutraceutical	L-Valine	CC(C)[C@H](N)C(O)=O
ECHS1	DB00123	enoyl CoA hydratase, short chain, 1, mitochondrial	approved; nutraceutical	L-Lysine	NCCCC[C@H](N)C(O)=O
ECI1	DB02910	enoyl-CoA delta isomerase 1	experimental	Octanoyl-Coenzyme A	CCCCCCCC(=O)SCCNC(=O)CCNC(=O)[C@@H](O)C(C)(C)CO[P@](O)(=O)O[P@@](O)(=O)OC[C@@H]1O[C@H]([C@H](O)[C@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N
ECI1	DB03127	enoyl-CoA delta isomerase 1	experimental	Benzamidine	NC(=[NH2+])C1=CC=CC=C1
ECI2	DB08231	enoyl-CoA delta isomerase 2	experimental	MYRISTIC ACID	CCCCCCCCCCCCCC(O)=O
EEF2	DB02059	eukaryotic translation elongation factor 2	experimental	Adenosine-5-Diphosphoribose	NC1=C2N=CN([C@@H]3O[C@H](CO[P@@](O)(=O)O[P@@](O)(=O)OC[C@H]4O[C@H](O)[C@H](O)[C@@H]4O)[C@@H](O)[C@H]3O)C2=NC=N1
EEF2	DB03223	eukaryotic translation elongation factor 2	experimental	Diphthamide	C[N+](C)(C)[C@@H](CCc1ncc(C[C@H](N)C(O)=O)n1)C(N)=O
EEF2	DB04315	eukaryotic translation elongation factor 2	experimental	Guanosine-5'-Diphosphate	NC1=NC2=C(N=CN2[C@@H]2O[C@@H](CO[P@](O)(=O)OP(O)(O)=O)[C@H](O)[C@H]2O)C(=O)N1
EEF2	DB08348	eukaryotic translation elongation factor 2	experimental	N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE	CN(C)CC(=O)NC1=CC2=C(NC(=O)C3=CC=CC=C23)C=C1
EEF2	DB00877	eukaryotic translation elongation factor 2	approved; investigational	Sirolimus	CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1O
EHHADH	DB00157	enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
EIF2B5	DB00877	eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa	approved; investigational	Sirolimus	CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1O
EIF2S1	DB00877	eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa	approved; investigational	Sirolimus	CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1O
EIF2S2	DB00877	eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa	approved; investigational	Sirolimus	CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1O
EIF2S3	DB00877	eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa	approved; investigational	Sirolimus	CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1O
EIF3A	DB00877	eukaryotic translation initiation factor 3, subunit A	approved; investigational	Sirolimus	CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1O
EIF4A1	DB00877	eukaryotic translation initiation factor 4A1	approved; investigational	Sirolimus	CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1O
EIF4A1	DB01033	eukaryotic translation initiation factor 4A1	approved	Mercaptopurine	S=C1N=CNC2=C1NC=N2
EIF4A1	DB00563	eukaryotic translation initiation factor 4A1	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
EIF4B	DB00877	eukaryotic translation initiation factor 4B	approved; investigational	Sirolimus	CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1O
EIF4E	DB01649	eukaryotic translation initiation factor 4E	experimental	7-Methyl-Gpppa	CN1C=[N+]([C@@H]2O[C@H](CO[P@](O)(=O)O[P@](O)(=O)O[P@](O)(=O)OC[C@H]3O[C@H]([C@H](O)[C@@H]3O)N3C=NC4=C(N)N=CN=C34)[C@@H](O)[C@H]2O)C2=C1C(=O)N=C(N)N2
EIF4E	DB01960	eukaryotic translation initiation factor 4E	experimental	7n-Methyl-8-Hydroguanosine-5'-Diphosphate	CN1CN([C@@H]2O[C@@H](CO[P@](O)(=O)OP(O)(O)=O)[C@H](O)[C@H]2O)C2=C1C(=O)NC(N)=N2
EIF4E	DB02716	eukaryotic translation initiation factor 4E	experimental	7-Methyl-Guanosine-5'-Triphosphate	C[N+]1=CN([C@@H]2O[C@@H](CO[P@](O)(=O)O[P@@](O)(=O)OP(O)(O)=O)[C@H](O)[C@H]2O)C2=C1C(=O)NC(N)=N2
EIF4E	DB08217	eukaryotic translation initiation factor 4E	experimental	2,2,5,5-TETRAMETHYL-3-(SULFANYLMETHYL)-2,5-DIHYDRO-1H-PYRROL-1-OL	CC1(C)C=C(CS)C(C)(C)N1O
EIF4E	DB00877	eukaryotic translation initiation factor 4E	approved; investigational	Sirolimus	CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1O
EIF4EBP1	DB00877	eukaryotic translation initiation factor 4E binding protein 1	approved; investigational	Sirolimus	CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1O
EIF4G1	DB00877	eukaryotic translation initiation factor 4 gamma, 1	approved; investigational	Sirolimus	CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1O
ELOVL4	DB00132	ELOVL fatty acid elongase 4	approved; nutraceutical	Alpha-Linolenic Acid	CC\C=C/C\C=C/C\C=C/CCCCCCCC(O)=O
ENO1	DB04066	enolase 1, (alpha)	experimental	Para-Coumaric Acid	OC(=O)\C=C\C1=CC=C(O)C=C1
ENPP1	DB00811	ectonucleotide pyrophosphatase/phosphodiesterase 1	approved	Ribavirin	NC(=O)C1=NN(C=N1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
ENPP1	DB01143	ectonucleotide pyrophosphatase/phosphodiesterase 1	approved; investigational	Amifostine	NCCCNCCSP(O)(O)=O
ENPP1	DB00131	ectonucleotide pyrophosphatase/phosphodiesterase 1	approved; nutraceutical	Adenosine monophosphate	NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
ENPP1	DB00171	ectonucleotide pyrophosphatase/phosphodiesterase 1	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
EP300	DB00171	E1A binding protein p300	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
EP300	DB00119	E1A binding protein p300	approved; nutraceutical	Pyruvic acid	CC(=O)C(O)=O
EP300	DB01234	E1A binding protein p300	approved; investigational	Dexamethasone	C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
EP300	DB00269	E1A binding protein p300	approved	Chlorotrianisene	COC1=CC=C(C=C1)C(Cl)=C(C1=CC=C(OC)C=C1)C1=CC=C(OC)C=C1
EP300	DB00286	E1A binding protein p300	approved	Conjugated Estrogens	[Na+].C[C@]12CC[C@H]3[C@@H](CCC4=CC(OS([O-])(=O)=O)=CC=C34)[C@@H]1CCC2=O
EP300	DB00890	E1A binding protein p300	approved	Dienestrol	CC=C(C(=CC)C1=CC=C(O)C=C1)C1=CC=C(O)C=C1
EP300	DB00255	E1A binding protein p300	approved	Diethylstilbestrol	CCC(=C(CC)C1=CC=C(O)C=C1)C1=CC=C(O)C=C1
EP300	DB00783	E1A binding protein p300	approved; investigational	Estradiol	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CC[C@@H]2O
EP300	DB00655	E1A binding protein p300	approved	Estrone	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CCC2=O
EP300	DB00977	E1A binding protein p300	approved	Ethinyl Estradiol	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CC[C@@]2(O)C#C
EPHX1	DB00252	epoxide hydrolase 1, microsomal (xenobiotic)	approved	Phenytoin	O=C1NC(=O)C(N1)(C1=CC=CC=C1)C1=CC=CC=C1
EPHX1	DB01248	epoxide hydrolase 1, microsomal (xenobiotic)	approved; investigational	Docetaxel	CC(=O)O[C@@]12CO[C@@H]1C[C@H](O)[C@]1(C)[C@@H]2[C@H](OC(=O)C2=CC=CC=C2)[C@]2(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C3=CC=CC=C3)C(C)=C([C@@H](O)C1=O)C2(C)C
EPHX1	DB00564	epoxide hydrolase 1, microsomal (xenobiotic)	approved; investigational	Carbamazepine	NC(=O)N1C2=CC=CC=C2C=CC2=CC=CC=C12
EPHX1	DB00313	epoxide hydrolase 1, microsomal (xenobiotic)	approved; investigational	Valproic Acid	CCCC(CCC)C(O)=O
EPHX1	DB00917	epoxide hydrolase 1, microsomal (xenobiotic)	approved	Dinoprostone	CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O
EPHX1	DB01240	epoxide hydrolase 1, microsomal (xenobiotic)	approved	Epoprostenol	CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)C[C@@H]2OC(C[C@H]12)=CCCCC(O)=O
EPHX1	DB00682	epoxide hydrolase 1, microsomal (xenobiotic)	approved	Warfarin	CC(=O)CC(C1=CC=CC=C1)C1=C(O)OC2=CC=CC=C2C1=O
EPHX2	DB01248	epoxide hydrolase 2, cytoplasmic	approved; investigational	Docetaxel	CC(=O)O[C@@]12CO[C@@H]1C[C@H](O)[C@]1(C)[C@@H]2[C@H](OC(=O)C2=CC=CC=C2)[C@]2(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C3=CC=CC=C3)C(C)=C([C@@H](O)C1=O)C2(C)C
EPRS	DB00142	glutamyl-prolyl-tRNA synthetase	approved; nutraceutical	L-Glutamic Acid	N[C@@H](CCC(O)=O)C(O)=O
EPRS	DB00172	glutamyl-prolyl-tRNA synthetase	approved; nutraceutical	L-Proline	OC(=O)[C@@H]1CCCN1
EPRS	DB02510	glutamyl-prolyl-tRNA synthetase	experimental	'5'-O-(N-(L-Prolyl)-Sulfamoyl)Adenosine	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](COS(=O)(=O)NC(=O)[C@@H]2CCCN2)[C@H](O)[C@H]1O
EPRS	DB02684	glutamyl-prolyl-tRNA synthetase	experimental	5'-O-(N-(L-Cysteinyl)-Sulfamoyl)Adenosine	N[C@H](CS)C(=O)NS(=O)(=O)OC[C@@H]1O[C@H]([C@H](O)[C@H]1O)N1C=NC2=C1N=CN=C2N
EPRS	DB03376	glutamyl-prolyl-tRNA synthetase	experimental	'5'-O-(N-(L-Alanyl)-Sulfamoyl)Adenosine	C[C@H](N)C(=O)NS(=O)(=O)OC[C@@H]1O[C@H]([C@H](O)[C@H]1O)N1C=NC2=C1N=CN=C2N
EPRS	DB00145	glutamyl-prolyl-tRNA synthetase	approved; nutraceutical	Glycine	NCC(O)=O
EPRS	DB00160	glutamyl-prolyl-tRNA synthetase	approved; nutraceutical	L-Alanine	C[C@H](N)C(O)=O
EPRS	DB00125	glutamyl-prolyl-tRNA synthetase	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
EPRS	DB00151	glutamyl-prolyl-tRNA synthetase	approved; nutraceutical	L-Cysteine	N[C@@H](CS)C(O)=O
EPRS	DB00130	glutamyl-prolyl-tRNA synthetase	approved; nutraceutical; investigational	L-Glutamine	N[C@@H](CCC(N)=O)C(O)=O
EPRS	DB00117	glutamyl-prolyl-tRNA synthetase	approved; nutraceutical	L-Histidine	N[C@@H](CC1=CN=CN1)C(O)=O
EPRS	DB00149	glutamyl-prolyl-tRNA synthetase	approved; nutraceutical	L-Leucine	CC(C)CC(N)C(O)=O
EPRS	DB00123	glutamyl-prolyl-tRNA synthetase	approved; nutraceutical	L-Lysine	NCCCC[C@H](N)C(O)=O
EPRS	DB00134	glutamyl-prolyl-tRNA synthetase	approved; nutraceutical	L-Methionine	CSCC[C@H](N)C(O)=O
EPRS	DB00120	glutamyl-prolyl-tRNA synthetase	approved; nutraceutical	L-Phenylalanine	N[C@@H](CC1=CC=CC=C1)C(O)=O
EPRS	DB00133	glutamyl-prolyl-tRNA synthetase	approved; nutraceutical	L-Serine	N[C@@H](CO)C(O)=O
EPRS	DB00156	glutamyl-prolyl-tRNA synthetase	approved; nutraceutical	L-Threonine	C[C@@H](O)[C@H](N)C(O)=O
EPRS	DB00150	glutamyl-prolyl-tRNA synthetase	approved; nutraceutical	L-Tryptophan	N[C@@H](CC1=CNC2=CC=CC=C12)C(O)=O
EPRS	DB00135	glutamyl-prolyl-tRNA synthetase	approved; nutraceutical	L-Tyrosine	N[C@@H](CC1=CC=C(O)C=C1)C(O)=O
EPRS	DB00161	glutamyl-prolyl-tRNA synthetase	approved; nutraceutical	L-Valine	CC(C)[C@H](N)C(O)=O
ESRRA	DB00197	estrogen-related receptor alpha	withdrawn	Troglitazone	CC1=C(C)C2=C(CCC(C)(COC3=CC=C(CC4SC(=O)NC4=O)C=C3)O2)C(C)=C1O
ESRRA	DB06833	estrogen-related receptor alpha	experimental	1-CYCLOHEXYL-N-{[1-(4-METHYLPHENYL)-1H-INDOL-3-YL]METHYL}METHANAMINE	CC1=CC=C(C=C1)N1C=C(CNCC2CCCCC2)C2=CC=CC=C12
ESRRA	DB01241	estrogen-related receptor alpha	approved	Gemfibrozil	CC1=CC(OCCCC(C)(C)C(O)=O)=C(C)C=C1
F10	DB00170	coagulation factor X	approved; nutraceutical	Menadione	CC1=CC(=O)C2=CC=CC=C2C1=O
F10	DB00569	coagulation factor X	approved; investigational	Fondaparinux sodium	[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].CO[C@H]1O[C@H](COS([O-])(=O)=O)[C@@H](O[C@@H]2O[C@H]([C@@H](O[C@H]3O[C@H](COS([O-])(=O)=O)[C@@H](O[C@@H]4O[C@@H]([C@@H](O[C@H]5O[C@H](COS([O-])(=O)=O)[C@@H](O)[C@H](O)[C@H]5NS([O-])(=O)=O)[C@H](O)[C@H]4O)C([O-])=O)[C@H](OS([O-])(=O)=O)[C@H]3NS([O-])(=O)=O)[C@H](O)[C@H]2OS([O-])(=O)=O)C([O-])=O)[C@H](O)[C@H]1NS([O-])(=O)=O
F10	DB01109	coagulation factor X	approved; investigational	Heparin	CC(=O)NC1C(O)OC(COS(O)(=O)=O)C(OC2OC(C(OC3OC(CO)C(OC4OC(C(O)C(O)C4OS(O)(=O)=O)C(O)=O)C(OS(O)(=O)=O)C3NS(O)(=O)=O)C(O)C2OS(O)(=O)=O)C(O)=O)C1O
F10	DB01225	coagulation factor X	approved; investigational	Enoxaparin	CC(=O)NC1C(O)OC(COS(O)(=O)=O)C(OC2OC(C(OC3OC(CO)C(OC4OC(C(O)C(O)C4OS(O)(=O)=O)C(O)=O)C(OS(O)(=O)=O)C3NS(O)(=O)=O)C(O)C2OS(O)(=O)=O)C(O)=O)C1O
F10	DB03847	coagulation factor X	experimental	Gamma-Carboxy-Glutamic Acid	N[C@@H](CC(C(O)=O)C(O)=O)C(O)=O
F10	DB04673	coagulation factor X	experimental	4-[(5-CHLOROINDOL-2-YL)SULFONYL]-2-(2-METHYLPROPYL)-1-[[5-(PYRIDIN-4-YL)PYRIMIDIN-2-YL]CARBONYL]PIPERAZINE	ClC1=CC2=C(NC(=C2)S(=O)(=O)N2CCN(CC2)C(=O)C2=NC=C(C=N2)C2=CC=NC=C2)C=C1
F10	DB06920	coagulation factor X	experimental	(2R,4R)-N~1~-(4-CHLOROPHENYL)-N~2~-[2-FLUORO-4-(2-OXOPYRIDIN-1(2H)-YL)PHENYL]-4-METHOXYPYRROLIDINE-1,2-DICARBOXAMIDE	CO[C@@H]1C[C@@H](N(C1)C(=O)NC1=CC=C(Cl)C=C1)C(=O)NC1=CC=C(C=C1F)N1C=CC=CC1=O
F10	DB07211	coagulation factor X	experimental	(2R)-2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}PROPENE-1-SULFONAMIDE	C[C@@H](C(=O)N1CCOCC1)N1CC[C@H](NS(=O)(=O)\C=C(/C)C2=CC=C(Cl)S2)C1=O
F10	DB07261	coagulation factor X	experimental	THIENO[3,2-B]PYRIDINE-2-SULFONIC ACID [1-(1-AMINO-ISOQUINOLIN-7-YLMETHYL)-2-OXO-PYRROLDIN-3-YL]-AMIDE	NC1=NC=CC2=C1C=C(CN1CC[C@H](NS(=O)(=O)C3=CC4=C(S3)C=CC=N4)C1=O)C=C2
F10	DB07277	coagulation factor X	experimental	2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}ETHANESULFONAMIDE	C[C@H](N1CC[C@H](NS(=O)(=O)CCC2=CC=C(Cl)S2)C1=O)C(=O)N1CCOCC1
F10	DB07278	coagulation factor X	experimental	2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}ETHENESULFONAMIDE	C[C@@H](C(=O)N1CCOCC1)N1CC[C@H](NS(=O)(=O)\C=C\C2=CC=C(Cl)S2)C1=O
F10	DB07605	coagulation factor X	experimental	2-({4-[(5-CHLORO-1H-INDOL-2-YL)SULFONYL]PIPERAZIN-1-YL}CARBONYL)THIENO[3,2-B]PYRIDINE 4-OXIDE	[O-][N+]1=CC=CC2=C1C=C(S2)C(=O)N1CCN(CC1)S(=O)(=O)C1=CC2=CC(Cl)=CC=C2N1
F10	DB07629	coagulation factor X	experimental	N-((1R,2S)-2-(5-CHLORO-1H-INDOLE-2-CARBOXAMIDO)CYCLOHEXYL)-5-METHYL-4,5,6,7-TETRAHYDROTHIAZOLO[5,4-C]PYRIDINE-2-CARBOXAMIDE	CN1CCC2=C(C1)SC(=N2)C(=O)N[C@@H]1CCCC[C@@H]1NC(=O)C1=CC2=C(N1)C=CC(Cl)=C2
F10	DB07630	coagulation factor X	experimental	N-((1R,2R)-2-(5-CHLORO-1H-INDOLE-2-CARBOXAMIDO)CYCLOHEXYL)-5-METHYL-4,5,6,7-TETRAHYDROTHIAZOLO[5,4-C]PYRIDINE-2-CARBOXAMIDE	CN1CCC2=C(C1)SC(=N2)C(=O)N[C@@H]1CCCC[C@H]1NC(=O)C1=CC2=C(N1)C=CC(Cl)=C2
F10	DB07800	coagulation factor X	experimental	N-(2-(((5-CHLORO-2-PYRIDINYL)AMINO)SULFONYL)PHENYL)-4-(2-OXO-1(2H)-PYRIDINYL)BENZAMIDE	ClC1=CN=C(NS(=O)(=O)C2=C(NC(=O)C3=CC=C(C=C3)N3C=CC=CC3=O)C=CC=C2)C=C1
F10	DB07804	coagulation factor X	experimental	5-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}-1H-1,2,4-TRIAZOLE-3-SULFONAMIDE	C[C@H](N1CC[C@H](NS(=O)(=O)C2=NNC(=N2)C2=CC=C(Cl)S2)C1=O)C(=O)N1CCOCC1
F10	DB07843	coagulation factor X	experimental	5-CHLORO-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}-1-BENZOTHIOPHENE-2-SULFONAMIDE	C[C@H](N1CC[C@H](NS(=O)(=O)C2=CC3=C(S2)C=CC(Cl)=C3)C1=O)C(=O)N1CCOCC1
F10	DB07844	coagulation factor X	experimental	6-CHLORO-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}-1-BENZOTHIOPHENE-2-SULFONAMIDE	C[C@H](N1CC[C@H](NS(=O)(=O)C2=CC3=C(S2)C=C(Cl)C=C3)C1=O)C(=O)N1CCOCC1
F10	DB07847	coagulation factor X	experimental	6-CHLORO-N-{(3S)-1-[(1S)-1-METHYL-2-(4-MORPHOLINYL)-2-OXO ETHYL]-2-OXO-3-PYRROLIDINYL}-2-NAPHTHALENESULFONAMIDE	C[C@H](N1CC[C@H](NS(=O)(=O)C2=CC3=CC=C(Cl)C=C3C=C2)C1=O)C(=O)N1CCOCC1
F10	DB07848	coagulation factor X	experimental	5-CHLORO-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-5-CHLORO-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-SULFONAMIDE	C[C@H](N1CC[C@H](NS(=O)(=O)C2=CC3=C(N2)C=CC(Cl)=C3)C1=O)C(=O)N1CCOCC1
F10	DB07872	coagulation factor X	experimental	5-chloro-N-[(3R)-1-(2-{[2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl]amino}-2-oxoethyl)pyrrolidin-3-yl]thiophene-2-carboxamide	FC1=C(NC(=O)CN2CC[C@H](C2)NC(=O)C2=CC=C(Cl)S2)C=CC(=C1)N1C=CC=CC1=O
F10	DB07875	coagulation factor X	experimental	5-Chloro-thiophene-2-carboxylic acid ((3S,4S)-1-{[2-fluoro-4-(2-oxo-2H-pyridin-1-yl)-phenylcarbamoyl]-methyl}-4-hydroxy-pyrrolidin-3-yl)-amide	O[C@H]1CN(CC(=O)NC2=C(F)C=C(C=C2)N2C=CC=CC2=O)C[C@@H]1NC(=O)C1=CC=C(Cl)S1
F10	DB07973	coagulation factor X	experimental	N-(1-ISOPROPYLPIPERIDIN-4-YL)-1-(3-METHOXYBENZYL)-1H-INDOLE-2-CARBOXAMIDE	COC1=CC(CN2C(=CC3=C2C=CC=C3)C(=O)NC2CCN(CC2)C(C)C)=CC=C1
F10	DB07974	coagulation factor X	experimental	1-{2-[(4-CHLOROPHENYL)AMINO]-2-OXOETHYL}-N-(1-ISOPROPYLPIPERIDIN-4-YL)-1H-INDOLE-2-CARBOXAMIDE	CC(C)N1CCC(CC1)NC(=O)C1=CC2=C(C=CC=C2)N1CC(=O)NC1=CC=C(Cl)C=C1
F10	DB08143	coagulation factor X	experimental	5-CHLORO-THIOPHENE-2-CARBOXYLIC ACID ((3S,4S)-4-FLUORO- 1-{[2-FLUORO-4-(2-OXO-2H-PYRIDIN-1-YL)-PHENYLCARBAMOYL]-METHYL}-PYRROLIDIN-3-YL)-AMIDE	F[C@H]1CN(CC(=O)NC2=CC=C(C=C2F)N2C=CC=CC2=O)C[C@@H]1NC(=O)C1=CC=C(Cl)S1
F10	DB08173	coagulation factor X	experimental	5-CHLORO-N-(2-(4-(2-OXOPYRIDIN-1(2H)-YL)BENZAMIDO)ETHYL)THIOPHENE-2-CARBOXAMIDE	ClC1=CC=C(S1)C(=O)NCCNC(=O)C1=CC=C(C=C1)N1C=CC=CC1=O
F10	DB08174	coagulation factor X	experimental	5-CHLORO-N-((1R,2S)-2-(4-(2-OXOPYRIDIN-1(2H)-YL)BENZAMIDO) CYCLOPENTYL)THIOPHENE-2-CARBOXAMIDE	ClC1=CC=C(S1)C(=O)N[C@@H]1CCC[C@@H]1NC(=O)C1=CC=C(C=C1)N1C=CC=CC1=O
F10	DB08426	coagulation factor X	experimental	THIENO[3,2-B]PYRIDINE-2-SULFONIC ACID [2-OXO-1-(1H-PYRROLO[2,3-C]PYRIDIN-2-YLMETHYL)-PYRROLIDIN-3-YL]-AMIDE	O=C1[C@H](CCN1CC1=CC2=C(N1)C=NC=C2)NS(=O)(=O)C1=CC2=C(S1)C=CC=N2
F10	DB08477	coagulation factor X	experimental	5-chloro-N-({(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide	ClC1=CC=C(S1)C(=O)NC[C@H]1CN(C(=O)O1)C1=CC=C(C=C1)N1CCOCC1=O
F10	DB08487	coagulation factor X	experimental	3-({4-[(6-CHLORO-1-BENZOTHIEN-2-YL)SULFONYL]-2-OXOPIPERAZIN-1-YL}METHYL)BENZENECARBOXIMIDAMIDE	NC(=N)C1=CC(CN2CCN(CC2=O)S(=O)(=O)C2=CC3=C(S2)C=C(Cl)C=C3)=CC=C1
F10	DB08488	coagulation factor X	experimental	4-{[(E)-2-(5-CHLOROTHIEN-2-YL)VINYL]SULFONYL}-1-(1H-PYRROLO[3,2-C]PYRIDIN-2-YLMETHYL)PIPERAZIN-2-ONE	ClC1=CC=C(S1)\C=C\S(=O)(=O)N1CCN(CC2=CC3=C(N2)C=CN=C3)C(=O)C1
F10	DB08495	coagulation factor X	experimental	4-({4-[(6-CHLORO-1-BENZOTHIEN-2-YL)SULFONYL]-2-OXOPIPERAZIN-1-YL}METHYL)BENZENECARBOXIMIDAMIDE	NC(=N)C1=CC=C(CN2CCN(CC2=O)S(=O)(=O)C2=CC3=C(S2)C=C(Cl)C=C3)C=C1
F10	DB08745	coagulation factor X	experimental	4-[[(1E)-2-(4-CHLOROPHENYL)ETHENYL]SULFONYL]-1-[[1-(4-PYRIDINYL)-4-PIPERIDINYL]METHYL]PIPERAZINONE	ClC1=CC=C(\C=C\S(=O)(=O)N2CCN(CC3CCN(CC3)C3=CC=NC=C3)C(=O)C2)C=C1
F10	DB08746	coagulation factor X	experimental	1-[[(1E)-2-(4-CHLOROPHENYL)ETHENYL]SULFONYL]-4-[[1-(4-PYRIDINYL)-4-PIPERIDINYL]METHYL]PIPERAZINE	ClC1=CC=C(\C=C\S(=O)(=O)N2CCN(CC3CCN(CC3)C3=CC=NC=C3)CC2)C=C1
F10	DB00682	coagulation factor X	approved	Warfarin	CC(=O)CC(C1=CC=CC=C1)C1=C(O)OC2=CC=CC=C2C1=O
F2	DB00170	coagulation factor II (thrombin)	approved; nutraceutical	Menadione	CC1=CC(=O)C2=CC=CC=C2C1=O
F2	DB00278	coagulation factor II (thrombin)	approved; investigational	Argatroban	C[C@@H]1CCN([C@H](C1)C(O)=O)C(=O)[C@H](CCCN=C(N)N)NS(=O)(=O)C1=CC=CC2=C1NC[C@H](C)C2
F2	DB01123	coagulation factor II (thrombin)	approved	Proflavine	NC1=CC2=NC3=C(C=CC(N)=C3)C=C2C=C1
F2	DB01766	coagulation factor II (thrombin)	experimental	Beta-(2-Naphthyl)-Alanine	N[C@@H](CC1=CC=C2C=CC=CC2=C1)C(O)=O
F2	DB01767	coagulation factor II (thrombin)	experimental	Hemi-Babim	NC(=N)C1=CC2=C(NC(CC3=NC4=C(N3)C=CC=C4)=N2)C=C1
F2	DB02193	coagulation factor II (thrombin)	experimental	2-(2-Hydroxy-Phenyl)-1h-Benzoimidazole-5-Carboxamidine	NC(=[NH2+])C1=CC2=C(N\C(N2)=C2/C=CC=CC2=O)C=C1
F2	DB02351	coagulation factor II (thrombin)	experimental	Hirulog	CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)CNC(=O)CNC(=O)CNC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](N)CC1=CC=CC=C1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC(C)C)C(O)=O
F2	DB02723	coagulation factor II (thrombin)	experimental	4-Oxo-2-Phenylmethanesulfonyl-Octahydro-Pyrrolo[1,2-a]Pyrazine-6-Carboxylic Acid [1-(N-Hydroxycarbamimidoyl)-Piperidin-4-Ylmethyl]-Amide	O\N=C(/N)N1CCC(CC1)CNC(=O)[C@@H]1CC[C@H]2CN(CC(=O)N12)S(=O)(=O)CC1=CC=CC=C1
F2	DB03136	coagulation factor II (thrombin)	experimental	4-Iodobenzo[B]Thiophene-2-Carboxamidine	NC(=[NH2+])C1=CC2=C(S1)C=CC=C2I
F2	DB03159	coagulation factor II (thrombin)	experimental	CRA_8696	NC(=[NH2+])C1=CC=C2NC(=CC2=C1)C1=CC=CC(=C1[O-])C1=CC=CC=C1
F2	DB03847	coagulation factor II (thrombin)	experimental	Gamma-Carboxy-Glutamic Acid	N[C@@H](CC(C(O)=O)C(O)=O)C(O)=O
F2	DB03865	coagulation factor II (thrombin)	experimental	6-Chloro-2-(2-Hydroxy-Biphenyl-3-Yl)-1h-Indole-5-Carboxamidine	NC(=[NH2+])C1=CC2=C(NC(=C2)C2=CC=CC(=C2O)C2=CC=CC=C2)C=C1Cl
F2	DB04136	coagulation factor II (thrombin)	experimental	Lysophosphotidylserine	CCCCCCCCCCCCCC[C@H](O)OC[C@H](O)CO[P@@](O)(=O)OC[C@H](N)C(O)=O
F2	DB04591	coagulation factor II (thrombin)	experimental	N-{2,2-DIFLUORO-2-[(2R)-PIPERIDIN-2-YL]ETHYL}-2-[2-(1H-1,2,4-TRIAZOL-1-YL)BENZYL][1,3]OXAZOLO[4,5-C]PYRIDIN-4-AMINE	FC(F)(CNC1=NC=CC2=C1N=C(CC1=CC=CC=C1N1C=NC=N1)O2)[C@H]1CCCCN1
F2	DB04697	coagulation factor II (thrombin)	experimental	TRANS-4-(GUANIDINOMETHYL)-CYCLOHEXANE-L-YL-D-3-CYCLOHEXYLALANYL-L-AZETIDINE-2-YL-D-TYROSINYL-L-HOMOARGININAMIDE	NC(N)=NCCCC[C@H](NC(=O)[C@@H](CC1=CC=C(O)C=C1)NC(=O)[C@@H]1CCN1C(=O)[C@@H](CC1CCCCC1)NC(=O)[C@@H]1CC[C@H](CN=C(N)N)CC1)C(N)=O
F2	DB04722	coagulation factor II (thrombin)	experimental	2-(3-CHLORO-6-{[2,2-DIFLUORO-2-(1-OXIDOPYRIDIN-2-YL)ETHYL]AMINO}-1-OXIDOPYRIDIN-2-YL)-N-[1-(3-CHLOROPHENYL)ETHYL]ACETAMIDE	C[C@@H](NC(=O)CC1=[N+]([O-])C(NCC(F)(F)C2=[N+]([O-])C=CC=C2)=CC=C1Cl)C1=CC=CC(Cl)=C1
F2	DB04771	coagulation factor II (thrombin)	experimental	1-GUANIDINO-4-(N-NITRO-BENZOYLAMINO-L-LEUCYL-L-PROLYLAMINO)BUTANE	CC(C)C[C@H](NC(=O)C1=CC=C(C=C1)[N+]([O-])=O)C(=O)N1CCC[C@H]1C(=O)NCCCCN=C(N)N
F2	DB04772	coagulation factor II (thrombin)	experimental	1-GUANIDINO-4-(N-PHENYLMETHANESULFONYL-L-LEUCYL-L-PROLYLAMINO)BUTANE	CC(C)C[C@H](NS(=O)(=O)CC1=CC=CC=C1)C(=O)N1CCC[C@H]1C(=O)NCCCCN=C(N)N
F2	DB04786	coagulation factor II (thrombin)	approved	Suramin	CC1=C(NC(=O)C2=CC(NC(=O)NC3=CC=CC(=C3)C(=O)NC3=C(C)C=CC(=C3)C(=O)NC3=C4C(C=C(C=C4S(O)(=O)=O)S(O)(=O)=O)=C(C=C3)S(O)(=O)=O)=CC=C2)C=C(C=C1)C(=O)NC1=C2C(C=C(C=C2S(O)(=O)=O)S(O)(=O)=O)=C(C=C1)S(O)(=O)=O
F2	DB04898	coagulation factor II (thrombin)	approved; withdrawn; investigational	Ximelagatran	CCOC(=O)CN[C@@H](C(=O)N1CC[C@H]1C(=O)NCC1=CC=C(C=C1)C(\N)=N\O)C1CCCCC1
F2	DB06695	coagulation factor II (thrombin)	approved	Dabigatran etexilate	CCCCCCOC(=O)N=C(N)C1=CC=C(NCC2=NC3=C(C=CC(=C3)C(=O)N(CCC(=O)OCC)C3=CC=CC=N3)N2C)C=C1
F2	DB06838	coagulation factor II (thrombin)	experimental	methyl L-phenylalaninate	COC(=O)[C@@H](N)CC1=CC=CC=C1
F2	DB06841	coagulation factor II (thrombin)	experimental	D-phenylalanyl-N-[(1S)-4-{[amino(iminio)methyl]amino}-1-(chloroacetyl)butyl]-L-prolinamide	N[C@H](CC1=CC=CC=C1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=[NH2+])C(=O)CCl
F2	DB06845	coagulation factor II (thrombin)	experimental	(S)-N-(4-carbamimidoylbenzyl)-1-(2-(cyclopentylamino)ethanoyl)pyrrolidine-2-carboxamide	NC(=N)C1=CC=C(CNC(=O)[C@@H]2CCCN2C(=O)CNC2CCCC2)C=C1
F2	DB06850	coagulation factor II (thrombin)	experimental	(S)-N-(4-carbamimidoylbenzyl)-1-(2-(cyclohexylamino)ethanoyl)pyrrolidine-2-carboxamide	NC(=N)C1=CC=C(CNC(=O)[C@@H]2CCCN2C(=O)CNC2CCCCC2)C=C1
F2	DB06853	coagulation factor II (thrombin)	experimental	N-cycloheptylglycyl-N-(4-carbamimidoylbenzyl)-L-prolinamide	NC(=N)C1=CC=C(CNC(=O)[C@@H]2CCCN2C(=O)CNC2CCCCCC2)C=C1
F2	DB06854	coagulation factor II (thrombin)	experimental	2-(2-HYDROXY-BIPHENYL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE	NC(=N)C1=CC2=C(NC(=N2)C2=CC=CC(C3=CC=CC=C3)=C2O)C=C1
F2	DB06858	coagulation factor II (thrombin)	experimental	N-cyclooctylglycyl-N-(4-carbamimidoylbenzyl)-L-prolinamide	NC(=N)C1=CC=C(CNC(=O)[C@@H]2CCCN2C(=O)CNC2CCCCCCC2)C=C1
F2	DB06859	coagulation factor II (thrombin)	experimental	N-ALLYL-5-AMIDINOAMINOOXY-PROPYLOXY-3-CHLORO-N-CYCLOPENTYLBENZAMIDE	NC(=N)NOCCCOC1=CC(Cl)=CC(=C1)C(=O)N(CC=C)C1CCCC1
F2	DB06861	coagulation factor II (thrombin)	experimental	6-(2-HYDROXY-CYCLOPENTYL)-7-OXO-HEPTANAMIDINE	NC(=N)CCCC[C@@H](C=O)[C@H]1CCC[C@@H]1O
F2	DB06865	coagulation factor II (thrombin)	experimental	6-CARBAMIMIDOYL-2-[2-HYDROXY-6-(4-HYDROXY-PHENYL)-INDAN-1-YL]-HEXANOIC ACID	NC(=N)CCCC[C@H]([C@@H]1[C@@H](O)CC2=C1C=C(C=C2)C1=CC=C(O)C=C1)C(O)=O
F2	DB06866	coagulation factor II (thrombin)	experimental	6-CARBAMIMIDOYL-2-[2-HYDROXY-5-(3-METHOXY-PHENYL)-INDAN-1-YL]-HEXANOIC ACID	COC1=CC=CC(=C1)C1=CC2=C(C=C1)[C@H]([C@@H](CCCCC(N)=N)C(O)=O)[C@@H](O)C2
F2	DB06868	coagulation factor II (thrombin)	experimental	N-(3-chlorobenzyl)-1-(4-methylpentanoyl)-L-prolinamide	CC(C)CCC(=O)N1CCC[C@H]1C(=O)NCC1=CC(Cl)=CC=C1
F2	DB06869	coagulation factor II (thrombin)	experimental	1-[2-AMINO-2-CYCLOHEXYL-ACETYL]-PYRROLIDINE-3-CARBOXYLIC ACID 5-CHLORO-2-(2-ETHYLCARBAMOYL-ETHOXY)-BENZYLAMIDE	CCNC(=O)COC1=C(CNC(=O)[C@@H]2CCCN2C(=O)[C@H](N)C2CCCCC2)C=C(Cl)C=C1
F2	DB06878	coagulation factor II (thrombin)	experimental	1-[(2R)-2-aminobutanoyl]-N-(3-chlorobenzyl)-L-prolinamide	CC[C@@H](N)C(=O)N1CCC[C@H]1C(=O)NCC1=CC=CC(Cl)=C1
F2	DB06911	coagulation factor II (thrombin)	experimental	D-leucyl-N-(3-chlorobenzyl)-L-prolinamide	CC(C)C[C@@H](N)C(=O)N1CCC[C@H]1C(=O)NCC1=CC(Cl)=CC=C1
F2	DB06919	coagulation factor II (thrombin)	experimental	D-phenylalanyl-N-(3-chlorobenzyl)-L-prolinamide	N[C@H](CC1=CC=CC=C1)C(=O)N1CCC[C@H]1C(=O)NCC1=CC(Cl)=CC=C1
F2	DB06929	coagulation factor II (thrombin)	experimental	1-butanoyl-N-(4-carbamimidoylbenzyl)-L-prolinamide	CCCC(=O)N1CCC[C@H]1C(=O)NCC1=CC=C(C=C1)C(N)=N
F2	DB06936	coagulation factor II (thrombin)	experimental	N-(4-carbamimidoylbenzyl)-1-(4-methylpentanoyl)-L-prolinamide	CC(C)CCC(=O)N1CCC[C@H]1C(=O)NCC1=CC=C(C=C1)C(N)=N
F2	DB06942	coagulation factor II (thrombin)	experimental	N-(4-carbamimidoylbenzyl)-1-(3-phenylpropanoyl)-L-prolinamide	NC(=N)C1=CC=C(CNC(=O)[C@@H]2CCCN2C(=O)CCC2=CC=CC=C2)C=C1
F2	DB06947	coagulation factor II (thrombin)	experimental	1-[(2R)-2-aminobutanoyl]-N-(4-carbamimidoylbenzyl)-L-prolinamide	CC[C@@H](N)C(=O)N1CCC[C@H]1C(=O)NCC1=CC=C(C=C1)C(N)=N
F2	DB06996	coagulation factor II (thrombin)	experimental	D-leucyl-N-(4-carbamimidoylbenzyl)-L-prolinamide	CC(C)C[C@@H](N)C(=O)N1CCC[C@H]1C(=O)NCC1=CC=C(C=C1)C(N)=N
F2	DB07005	coagulation factor II (thrombin)	experimental	D-phenylalanyl-N-{4-[amino(iminio)methyl]benzyl}-L-prolinamide	N[C@H](CC1=CC=CC=C1)C(=O)N1CCC[C@H]1C(=O)NCC1=CC=C(C=C1)C(N)=[NH2+]
F2	DB07016	coagulation factor II (thrombin)	experimental	(3R)-8-(dioxidosulfanyl)-3-methyl-1,2,3,4-tetrahydroquinoline	C[C@H]1CNC2=C(C1)C=CC=C2S(=O)=O
F2	DB07027	coagulation factor II (thrombin)	experimental	D-phenylalanyl-N-(3-fluorobenzyl)-L-prolinamide	N[C@H](CC1=CC=CC=C1)C(=O)N1CCC[C@H]1C(=O)NCC1=CC=CC(F)=C1
F2	DB07083	coagulation factor II (thrombin)	experimental	beta-phenyl-D-phenylalanyl-N-propyl-L-prolinamide	CCCNC(=O)[C@@H]1CCCN1C(=O)[C@H](N)C(C1=CC=CC=C1)C1=CC=CC=C1
F2	DB07088	coagulation factor II (thrombin)	experimental	(S)-N-(4-carbamimidoylbenzyl)-1-(2-(cyclopentyloxy)ethanoyl)pyrrolidine-2-carboxamide	NC(=N)C1=CC=C(CNC(=O)[C@@H]2CCCN2C(=O)COC2CCCC2)C=C1
F2	DB07091	coagulation factor II (thrombin)	experimental	(S)-N-(4-carbamimidoylbenzyl)-1-(2-(cyclohexyloxy)ethanoyl)pyrrolidine-2-carboxamide	NC(=N)C1=CC=C(CNC(=O)[C@@H]2CCCN2C(=O)COC2CCCCC2)C=C1
F2	DB07095	coagulation factor II (thrombin)	experimental	(S)-N-(4-carbamimidoylbenzyl)-1-(3-cyclopentylpropanoyl)pyrrolidine-2-carboxamide	NC(=N)C1=CC=C(CNC(=O)[C@@H]2CCCN2C(=O)CCC2CCCC2)C=C1
F2	DB07105	coagulation factor II (thrombin)	experimental	2-[2-(4-CHLORO-PHENYLSULFANYL)-ACETYLAMINO]-3-(4-GUANIDINO-PHENYL)-PROPIONAMIDE	NC(=N)NC1=CC=C(C[C@H](NC(=O)CSC2=CC=C(Cl)C=C2)C(N)=O)C=C1
F2	DB07120	coagulation factor II (thrombin)	experimental	N4-(N,N-DIPHENYLCARBAMOYL)-AMINOGUANIDINE	NC(=N)NNC(=O)N(C1=CC=CC=C1)C1=CC=CC=C1
F2	DB07128	coagulation factor II (thrombin)	experimental	N7-BUTYL-N2-(5-CHLORO-2-METHYLPHENYL)-5-METHYL[1,2,4]TRIAZOLO[1,5-A]PYRIMIDINE-2,7-DIAMINE	CCCCNC1=CC(C)=NC2=NC(NC3=CC(Cl)=CC=C3C)=NN12
F2	DB07131	coagulation factor II (thrombin)	experimental	(S)-N-(4-carbamimidoylbenzyl)-1-(3-cyclohexylpropanoyl)pyrrolidine-2-carboxamide	NC(=N)C1=CC=C(CNC(=O)[C@@H]2CCCN2C(=O)CCC2CCCCC2)C=C1
F2	DB07133	coagulation factor II (thrombin)	experimental	D-phenylalanyl-N-(3-methylbenzyl)-L-prolinamide	CC1=CC=CC(CNC(=O)[C@@H]2CCCN2C(=O)[C@H](N)CC2=CC=CC=C2)=C1
F2	DB07143	coagulation factor II (thrombin)	experimental	D-phenylalanyl-N-benzyl-L-prolinamide	N[C@H](CC1=CC=CC=C1)C(=O)N1CCC[C@H]1C(=O)NCC1=CC=CC=C1
F2	DB07165	coagulation factor II (thrombin)	experimental	N-(5-CHLORO-BENZO[B]THIOPHEN-3-YLMETHYL)-2-[6-CHLORO-OXO-3-(2-PYRIDIN-2-YL-ETHYLAMINO)-2H-PYRAZIN-1-YL]-ACETAMIDE	O[C@@H]1N(CC(=O)NCC2=CSC3=CC=C(Cl)C=C23)[C@H](Cl)CN=C1NCCC1=NC=CC=C1
F2	DB07190	coagulation factor II (thrombin)	experimental	3-cyclohexyl-D-alanyl-N-(3-chlorobenzyl)-L-prolinamide	N[C@H](CC1CCCCC1)C(=O)N1CCC[C@H]1C(=O)NCC1=CC(Cl)=CC=C1
F2	DB07211	coagulation factor II (thrombin)	experimental	(2R)-2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}PROPENE-1-SULFONAMIDE	C[C@@H](C(=O)N1CCOCC1)N1CC[C@H](NS(=O)(=O)\C=C(/C)C2=CC=C(Cl)S2)C1=O
F2	DB07277	coagulation factor II (thrombin)	experimental	2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}ETHANESULFONAMIDE	C[C@H](N1CC[C@H](NS(=O)(=O)CCC2=CC=C(Cl)S2)C1=O)C(=O)N1CCOCC1
F2	DB07278	coagulation factor II (thrombin)	experimental	2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}ETHENESULFONAMIDE	C[C@@H](C(=O)N1CCOCC1)N1CC[C@H](NS(=O)(=O)\C=C\C2=CC=C(Cl)S2)C1=O
F2	DB07279	coagulation factor II (thrombin)	experimental	N-ETHYL-N-ISOPROPYL-3-METHYL-5-{[(2S)-2-(PYRIDIN-4-YLAMINO)PROPYL]OXY}BENZAMIDE	CCN(C(C)C)C(=O)C1=CC(C)=CC(OC[C@H](C)NC2=CC=NC=C2)=C1
F2	DB07353	coagulation factor II (thrombin)	experimental	4-(2,5-DIAMINO-5-HYDROXY-PENTYL)-PHENOL	N[C@@H](O)CC[C@@H](N)CC1=CC=C(O)C=C1
F2	DB07366	coagulation factor II (thrombin)	experimental	2-[N'-(4-AMINO-BUTYL)-HYDRAZINOCARBONYL]-PYRROLIDINE-1-CARBOXYLIC ACID BENZYL ESTER	NCCCCNNC(=O)[C@@H]1CCCN1C(=O)OCC1=CC=CC=C1
F2	DB07376	coagulation factor II (thrombin)	experimental	5-(DIMETHYLAMINO)-1-NAPHTHALENESULFONIC ACID(DANSYL ACID)	CN(C)C1=C2C=CC=C(C2=CC=C1)S(O)(=O)=O
F2	DB07400	coagulation factor II (thrombin)	experimental	1-ETHOXYCARBONYL-D-PHE-PRO-2(4-AMINOBUTYL)HYDRAZINE	CCOC(=O)N[C@H](CC1=CC=CC=C1)C(=O)N1CCC[C@H]1C(=O)NNCCCCN
F2	DB07440	coagulation factor II (thrombin)	experimental	4-TERT-BUTYLBENZENESULFONIC ACID	CC(C)(C)C1=CC=C(C=C1)S(O)(=O)=O
F2	DB07461	coagulation factor II (thrombin)	experimental	3-AMINO-3-BENZYL-9-CARBOXAMIDE[4.3.0]BICYCLO-1,6-DIAZANONAN-2-ONE	N[C@@]1(CC2=CC=CC=C2)CCN2CC[C@@H](C=O)N2C1=O
F2	DB07508	coagulation factor II (thrombin)	experimental	4-(5-BENZENESULFONYLAMINO-1-METHYL-1H-BENZOIMIDAZOL-2-YLMETHYL)-BENZAMIDINE	CN1C(CC2=CC=C(C=C2)C(N)=N)=NC2=C1C=CC(NS(=O)(=O)C1=CC=CC=C1)=C2
F2	DB07515	coagulation factor II (thrombin)	experimental	1-(2-{[(6-AMINO-2-METHYLPYRIDIN-3-YL)METHYL]AMINO}ETHYL)-6-CHLORO-3-[(2,2-DIFLUORO-2-PYRIDIN-2-YLETHYL)AMINO]-1,4-DIHYDROPYRAZIN-2-OL	C[C@H]1N[C@@H](N)CC[C@@H]1CNCCN1[C@H](O)C(NCC(F)(F)C2=NC=CC=C2)=NC=C1Cl
F2	DB07521	coagulation factor II (thrombin)	experimental	6-CHLORO-1-(2-{[(5-CHLORO-1-BENZOTHIEN-3-YL)METHYL]AMINO}ETHYL)-3-[(2-PYRIDIN-2-YLETHYL)AMINO]-1,4-DIHYDROPYRAZIN-2-OL	O[C@@H]1N(CCNCC2=CSC3=CC=C(Cl)C=C23)[C@@H](Cl)CN=C1NCC[C@@H]1CCCCN1
F2	DB07522	coagulation factor II (thrombin)	experimental	N-[(2R,3S)-3-AMINO-2-HYDROXY-4-PHENYLBUTYL]NAPHTHALENE-2-SULFONAMIDE	N[C@@H](CC1=CC=CC=C1)[C@H](O)CNS(=O)(=O)C1=CC=C2C=CC=CC2=C1
F2	DB07527	coagulation factor II (thrombin)	experimental	N-[(2R,3S)-3-AMINO-2-HYDROXY-4-PHENYLBUTYL]-4-METHOXY-2,3,6-TRIMETHYLBENZENESULFONAMIDE	COC1=CC(C)=C(C(C)=C1C)S(=O)(=O)NC[C@@H](O)[C@@H](N)CC1=CC=CC=C1
F2	DB07548	coagulation factor II (thrombin)	experimental	2-(6-CHLORO-3-{[2,2-DIFLUORO-2-(2-PYRIDINYL)ETHYL]AMINO}-2-OXO-1(2H)-PYRAZINYL)-N-[(2-FLUORO-6-PYRIDINYL)METHYL]ACETAMIDE	CC1=CN=C(NCC(F)(F)C2=CC=CC=N2)C(=O)N1CC(=O)NCC1=C(F)C=CC=N1
F2	DB07549	coagulation factor II (thrombin)	experimental	2-(6-CHLORO-3-{[2,2-DIFLUORO-2-(2-PYRIDINYL)ETHYL]AMINO}-2-OXO-1(2H)-PYRAZINYL)-N-[(2-FLUORO-3-METHYL-6-PYRIDINYL)METHYL]ACETAMIDE	CC1=C[NH+]=C(NCC(F)(F)C2=[NH+]C=CC=C2)C(=O)N1CC(=O)NCC1=C(F)C(C)=CC=N1
F2	DB07550	coagulation factor II (thrombin)	experimental	2-(6-CHLORO-3-{[2,2-DIFLUORO-2-(1-OXIDO-2-PYRIDINYL)ETHYL]AMINO}-2-OXO-1(2H)-PYRAZINYL)-N-[(2-FLUOROPHENYL)METHYL]ACETAMIDE	[O-][N+]1=CC=CC=C1C(F)(F)CNC1=NC=C(Cl)N(CC(=O)NCC2=C(F)C=CC=C2)C1=O
F2	DB07639	coagulation factor II (thrombin)	experimental	3-(7-DIAMINOMETHYL-NAPHTHALEN-2-YL)-PROPIONIC ACID ETHYL ESTER	CCOC(=O)[C@@H](CC1=CC=C2C=CC(=CC2=C1)C(N)N)C1=CC=C(O[C@H]2CCNC2)C=C1
F2	DB07658	coagulation factor II (thrombin)	experimental	AC-(D)PHE-PRO-BOROLYS-OH	CC(=O)N[C@H](CC1=CC=CC=C1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)B(O)O
F2	DB07659	coagulation factor II (thrombin)	experimental	AC-(D)PHE-PRO-BOROHOMOLYS-OH	CC(=O)N[C@H](CC1=CC=CC=C1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCCN)B(O)O
F2	DB07660	coagulation factor II (thrombin)	experimental	AC-(D)PHE-PRO-BOROHOMOORNITHINE-OH	CC(=O)N[C@H](CC1=CC=CC=C1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN)B(O)O
F2	DB07665	coagulation factor II (thrombin)	experimental	N-[2-(carbamimidamidooxy)ethyl]-2-{6-cyano-3-[(2,2-difluoro-2-pyridin-2-ylethyl)amino]-2-fluorophenyl}acetamide	NC(=N)NOCCNC(=O)CC1=C(C=CC(NCC(F)(F)C2=NC=CC=C2)=C1F)C#N
F2	DB07718	coagulation factor II (thrombin)	experimental	3-(4-HYDROXY-PHENYL)PYRUVIC ACID	OC(=O)C(=O)CC1=CC=C(O)C=C1
F2	DB07741	coagulation factor II (thrombin)	experimental	4-(1R,3AS,4R,8AS,8BR)-[1-DIFLUOROMETHYL-2-(4-FLUOROBENZYL)-3-OXODECAHYDROPYRROLO[3,4-A]PYRROLIZIN-4-YL]BENZAMIDINE	NC(N)C1=CC=C(C=C1)[C@H]1[C@@H]2[C@H]([C@@H]3CCCN13)[C@@H](C(F)F)N(CC1=CC=C(F)C=C1)C2=O
F2	DB07796	coagulation factor II (thrombin)	experimental	(3ASR,4RS,8ASR,8BRS)-4-(2-(4-FLUOROBENZYL)-1,3-DIOXODEACAHYDROPYRROLO[3,4-A] PYRROLIZIN-4-YL)BENZAMIDINE	NC(=[NH2+])C1=CC=C(C=C1)[C@H]1[C@@H]2[C@H]([C@@H]3CCCN13)C(=O)N(CC1=CC=C(F)C=C1)C2=O
F2	DB07809	coagulation factor II (thrombin)	experimental	4-({[4-(3-METHYLBENZOYL)PYRIDIN-2-YL]AMINO}METHYL)BENZENECARBOXIMIDAMIDE	CC1=CC=CC(=C1)C(=O)C1=CC=NC(NCC2=CC=C(C=C2)C(N)=N)=C1
F2	DB07897	coagulation factor II (thrombin)	experimental	1-(HYDROXYMETHYLENEAMINO)-8-HYDROXY-OCTANE	OCCCCCCCCNCO
F2	DB07934	coagulation factor II (thrombin)	experimental	[[CYCLOHEXANESULFONYL-GLYCYL]-3[PYRIDIN-4-YL-AMINOMETHYL]ALANYL]PIPERIDINE	O=C(CNS(=O)(=O)C1CCCCC1)N[C@H](CCNC1=CC=[NH+]C=C1)C(=O)N1CCCCC1
F2	DB07944	coagulation factor II (thrombin)	experimental	N-{3-METHYL-5-[2-(PYRIDIN-4-YLAMINO)-ETHOXY]-PHENYL}-BENZENESULFONAMIDE	CC1=CC(OCCNC2=CC=[NH+]C=C2)=CC(NS(=O)(=O)C2=CC=CC=C2)=C1
F2	DB07946	coagulation factor II (thrombin)	experimental	N-[2-({[amino(imino)methyl]amino}oxy)ethyl]-2-{6-chloro-3-[(2,2-difluoro-2-phenylethyl)amino]-2-fluorophenyl}acetamide	NC(=N)NOCCNC(=O)CC1=C(Cl)C=CC(NCC(F)(F)C2=CC=CC=C2)=C1F
F2	DB08061	coagulation factor II (thrombin)	experimental	4-[3-(4-CHLOROPHENYL)-1H-PYRAZOL-5-YL]PIPERIDINE	ClC1=CC=C(C=C1)C1=NNC(=C1)C1CCNCC1
F2	DB08062	coagulation factor II (thrombin)	experimental	3-(4-CHLOROPHENYL)-5-(METHYLTHIO)-4H-1,2,4-TRIAZOLE	CSC1=NN=C(N1)C1=CC=C(Cl)C=C1
F2	DB08152	coagulation factor II (thrombin)	experimental	{(2S)-1-[N-(tert-butoxycarbonyl)glycyl]pyrrolidin-2-yl}methyl (3-chlorophenyl)acetate	CC(C)(C)OC(=O)NCC(=O)N1CCC[C@H]1COC(=O)CC1=CC(Cl)=CC=C1
F2	DB08187	coagulation factor II (thrombin)	experimental	METHYL-PHE-PRO-AMINO-CYCLOHEXYLGLYCINE	CN[C@H](CC1=CC=CC=C1)C(=O)N1CCC[C@H]1C(=O)NC[C@@H]1CC[C@H](N)CC1
F2	DB08254	coagulation factor II (thrombin)	experimental	2-NAPHTHALENESULFONIC ACID	OS(=O)(=O)C1=CC2=C(C=CC=C2)C=C1
F2	DB08422	coagulation factor II (thrombin)	experimental	[PHENYLALANINYL-PROLINYL]-[2-(PYRIDIN-4-YLAMINO)-ETHYL]-AMINE	N[C@H](CC1=CC=CC=C1)C(=O)N1CCC[C@H]1C(=O)NCCNC1=CC=NC=C1
F2	DB08546	coagulation factor II (thrombin)	experimental	4-[(3AS,4R,7R,8AS,8BR)-2-(1,3-BENZODIOXOL-5-YLMETHYL)-7-HYDROXY-1,3-DIOXODECAHYDROPYRROLO[3,4-A]PYRROLIZIN-4-YL]BENZENECARBOXIMIDAMIDE	NC(=N)C1=CC=C(C=C1)[C@H]1[C@@H]2[C@H]([C@@H]3C[C@@H](O)CN13)C(=O)N(CC1=CC=C3OCOC3=C1)C2=O
F2	DB08624	coagulation factor II (thrombin)	experimental	BENZOTHIAZOLE	N[C@@H](CCCNC(N)=N)C(=O)C1=NC2=CC=CC=C2S1
F2	DB00945	coagulation factor II (thrombin)	approved	Acetylsalicylic acid	CC(=O)OC1=CC=CC=C1C(O)=O
F2	DB00682	coagulation factor II (thrombin)	approved	Warfarin	CC(=O)CC(C1=CC=CC=C1)C1=C(O)OC2=CC=CC=C2C1=O
F2	DB00269	coagulation factor II (thrombin)	approved	Chlorotrianisene	COC1=CC=C(C=C1)C(Cl)=C(C1=CC=C(OC)C=C1)C1=CC=C(OC)C=C1
F2	DB00286	coagulation factor II (thrombin)	approved	Conjugated Estrogens	[Na+].C[C@]12CC[C@H]3[C@@H](CCC4=CC(OS([O-])(=O)=O)=CC=C34)[C@@H]1CCC2=O
F2	DB00890	coagulation factor II (thrombin)	approved	Dienestrol	CC=C(C(=CC)C1=CC=C(O)C=C1)C1=CC=C(O)C=C1
F2	DB00255	coagulation factor II (thrombin)	approved	Diethylstilbestrol	CCC(=C(CC)C1=CC=C(O)C=C1)C1=CC=C(O)C=C1
F2	DB00783	coagulation factor II (thrombin)	approved; investigational	Estradiol	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CC[C@@H]2O
F2	DB00655	coagulation factor II (thrombin)	approved	Estrone	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CCC2=O
F2	DB00977	coagulation factor II (thrombin)	approved	Ethinyl Estradiol	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CC[C@@]2(O)C#C
F2	DB00122	coagulation factor II (thrombin)	approved; nutraceutical	Choline	C[N+](C)(C)CCO
F2	DB00125	coagulation factor II (thrombin)	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
F2	DB00435	coagulation factor II (thrombin)	approved	Nitric Oxide	[N]=O
F2	DB00668	coagulation factor II (thrombin)	approved	Epinephrine	CNC[C@H](O)C1=CC(O)=C(O)C=C1
F2	DB00460	coagulation factor II (thrombin)	approved; investigational	Verteporfin	COC(=O)CCC1=C2NC(\C=C3/N=C(/C=C4\N\C(=C/C5=N/C(=C\2)/C(CCC(O)=O)=C5C)C(C=C)=C4C)C2=CC=C([C@@H](C(=O)OC)[C@@]32C)C(=O)OC)=C1C
F2	DB00717	coagulation factor II (thrombin)	approved	Norethindrone	C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@H]34)[C@@H]1CC[C@@]2(O)C#C
F7	DB00170	coagulation factor VII (serum prothrombin conversion accelerator)	approved; nutraceutical	Menadione	CC1=CC(=O)C2=CC=CC=C2C1=O
F7	DB04590	coagulation factor VII (serum prothrombin conversion accelerator)	experimental	(2R)-({4-[AMINO(IMINO)METHYL]PHENYL}AMINO){5-ETHOXY-2-FLUORO-3-[(3R)-TETRAHYDROFURAN-3-YLOXY]PHENYL}ACETICACID	CCOC1=CC([C@@H](NC2=CC=C(C=C2)C(N)=N)C(O)=O)=C(F)C(O[C@@H]2CCOC2)=C1
F7	DB04593	coagulation factor VII (serum prothrombin conversion accelerator)	experimental	3-({1-[3-CARBAMIMIDOYL-1-(4-CARBAMIMIDOYL-BENZYLCARBAMOYL)-PROPYLCARBAMOYL]-2-METHYL-BUTYLSULFAMOYL}-METHYL)-BENZOIC ACID	CC[C@@H](C)[C@@H](NS(=O)(=O)CC1=CC(=CC=C1)C(O)=O)C(=O)N[C@@H](CCC(N)=N)C(=O)NCC1=CC=C(C=C1)C(N)=N
F7	DB04606	coagulation factor VII (serum prothrombin conversion accelerator)	experimental	2-[2-ETHANESULFONYLAMINO-3-(5-PROPOXY-1H-INDOL-3-YL)-PROPIONYLAMINO]-PENTANEDIOIC ACID 5-AMIDE 1-(4-CARBAMIMIDOYL-BENZYLAMIDE)	CCCOC1=CC2=C(NC=C2C[C@@H](NS(=O)(=O)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)NCC2=CC=C(C=C2)C(N)=N)C=C1
F7	DB04758	coagulation factor VII (serum prothrombin conversion accelerator)	experimental	2-[2-ETHANESULFONYLAMINO-3-(1H-INDOL-3-YL)-PROPIONYLAMINO]-PENTANEDIOIC ACID 5-AMIDE 1-(4-CARBAMIM IDOYL-BENZYLAMIDE)	CCS(=O)(=O)N[C@H](CC1=CNC2=CC=CC=C12)C(=O)N[C@@H](CCC(N)=O)C(=O)NCC1=CC=C(C=C1)C(N)=N
F7	DB04767	coagulation factor VII (serum prothrombin conversion accelerator)	experimental	N-[1-(4-CARBAMIMIDOYL-BENZYLCARBAMOYL)-3-METHYLSULFANYL-PROPYL]-3-HYDROXY-2-PROPOXYAMINO-BUTYRAMID	CCCS(=O)(=O)N[C@H]([C@H](C)O)C(=O)N[C@@H](CCSC)C(=O)NCC1=CC=C(C=C1)C(N)=N
F7	DB07207	coagulation factor VII (serum prothrombin conversion accelerator)	experimental	2-(4-HYDROXY-5-PHENYL-1H-PYRAZOL-3-YL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE	NC(=N)C1=CC=C2NC(=NC2=C1)C1=NNC(=C1O)C1=CC=CC=C1
F7	DB07247	coagulation factor VII (serum prothrombin conversion accelerator)	experimental	[2'-HYDROXY-3'-(1H-PYRROLO[3,2-C]PYRIDIN-2-YL)-BIPHENYL-3-YLMETHYL]-UREA	NC(=O)NCC1=CC(=CC=C1)C1=C(O)C(=CC=C1)C1=CC2=C(N1)C=CN=C2
F7	DB07376	coagulation factor VII (serum prothrombin conversion accelerator)	experimental	5-(DIMETHYLAMINO)-1-NAPHTHALENESULFONIC ACID(DANSYL ACID)	CN(C)C1=C2C=CC=C(C2=CC=C1)S(O)(=O)=O
F7	DB08232	coagulation factor VII (serum prothrombin conversion accelerator)	experimental	{5-(5-AMINO-1H-PYRROLO[3,2-B]PYRIDIN-2-YL)-6-HYDROXY-3'-NITRO-BIPHENYL-3-YL]-ACETIC ACID	NC1=CC=C2NC(=CC2=N1)C1=CC(CC(O)=O)=CC(=C1O)C1=CC=CC(=C1)[N+]([O-])=O
F7	DB00175	coagulation factor VII (serum prothrombin conversion accelerator)	approved	Pravastatin	CC[C@H](C)C(=O)O[C@H]1C[C@H](O)C=C2C=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC(O)=O)[C@@H]12
F7	DB00682	coagulation factor VII (serum prothrombin conversion accelerator)	approved	Warfarin	CC(=O)CC(C1=CC=CC=C1)C1=C(O)OC2=CC=CC=C2C1=O
F9	DB00170	coagulation factor IX	approved; nutraceutical	Menadione	CC1=CC(=O)C2=CC=CC=C2C1=O
F9	DB03847	coagulation factor IX	experimental	Gamma-Carboxy-Glutamic Acid	N[C@@H](CC(C(O)=O)C(O)=O)C(O)=O
F9	DB00682	coagulation factor IX	approved	Warfarin	CC(=O)CC(C1=CC=CC=C1)C1=C(O)OC2=CC=CC=C2C1=O
F9	DB00668	coagulation factor IX	approved	Epinephrine	CNC[C@H](O)C1=CC(O)=C(O)C=C1
FABP6	DB02659	fatty acid binding protein 6, ileal	experimental	Cholic Acid	C[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C
FABP6	DB02691	fatty acid binding protein 6, ileal	experimental	N-Cholylglycine	C[C@H](CCC(=O)NCC(O)=O)[C@@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@H]4C[C@@H](O)CC[C@]4(C)[C@H]3C[C@@H](O)[C@]12C
FABP6	DB04348	fatty acid binding protein 6, ileal	experimental	Taurocholic Acid	C[C@H](CCC(=O)NCCS(O)(=O)=O)[C@@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@H]4C[C@@H](O)CC[C@]4(C)[C@H]3C[C@@H](O)[C@]12C
FABP6	DB00145	fatty acid binding protein 6, ileal	approved; nutraceutical	Glycine	NCC(O)=O
FADS1	DB00132	fatty acid desaturase 1	approved; nutraceutical	Alpha-Linolenic Acid	CC\C=C/C\C=C/C\C=C/CCCCCCCC(O)=O
FADS1	DB00159	fatty acid desaturase 1	approved; nutraceutical	Icosapent	CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O
FADS2	DB00132	fatty acid desaturase 2	approved; nutraceutical	Alpha-Linolenic Acid	CC\C=C/C\C=C/C\C=C/CCCCCCCC(O)=O
FAH	DB00143	fumarylacetoacetate hydrolase (fumarylacetoacetase)	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
FAH	DB00120	fumarylacetoacetate hydrolase (fumarylacetoacetase)	approved; nutraceutical	L-Phenylalanine	N[C@@H](CC1=CC=CC=C1)C(O)=O
FAH	DB00135	fumarylacetoacetate hydrolase (fumarylacetoacetase)	approved; nutraceutical	L-Tyrosine	N[C@@H](CC1=CC=C(O)C=C1)C(O)=O
FAH	DB00360	fumarylacetoacetate hydrolase (fumarylacetoacetase)	approved; investigational	Tetrahydrobiopterin	CC(O)C(O)C1CNC2=C(N1)C(=O)N=C(N)N2
FASN	DB01034	fatty acid synthase	approved	Cerulenin	CC=CCC=CCCC(=O)[C@H]1O[C@H]1C(N)=O
FASN	DB01083	fatty acid synthase	approved; investigational	Orlistat	CCCCCCCCCCC[C@@H](C[C@@H]1OC(=O)[C@H]1CCCCCC)OC(=O)[C@H](CC(C)C)NC=O
FASN	DB00363	fatty acid synthase	approved	Clozapine	CN1CCN(CC1)C1=NC2=CC(Cl)=CC=C2NC2=CC=CC=C12
FASN	DB00502	fatty acid synthase	approved	Haloperidol	OC1(CCN(CCCC(=O)C2=CC=C(F)C=C2)CC1)C1=CC=C(Cl)C=C1
FBP1	DB00131	fructose-1,6-bisphosphatase 1	approved; nutraceutical	Adenosine monophosphate	NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
FBP1	DB02778	fructose-1,6-bisphosphatase 1	experimental	2,5-Anhydroglucitol-1,6-Biphosphate	O[C@@H]1[C@@H](O)[C@H](COP(O)(O)=O)O[C@H]1COP(O)(O)=O
FBP1	DB02848	fructose-1,6-bisphosphatase 1	experimental	{4-[3-(6,7-Diethoxy-Quinazolin-4-Ylamino)-Phenyl]-Thiazol-2-Yl}-Methanol	CCOC1=C(OCC)C=C2C(NC3=CC=CC(=C3)C3=CSC(CO)=N3)=NC=NC2=C1
FBP1	DB04175	fructose-1,6-bisphosphatase 1	experimental	Mdl-29951	OC(=O)CCC1=C(NC2=C1C(Cl)=CC(Cl)=C2)C(O)=O
FBP1	DB04493	fructose-1,6-bisphosphatase 1	experimental	Fructose-6-Phosphate	OC[C@]1(O)O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O
FBP1	DB07270	fructose-1,6-bisphosphatase 1	experimental	N-[7-(3-AMINOPHENYL)-5-METHOXY-1,3-BENZOXAZOL-2-YL]-2,5-DICHLOROBENZENESULFONAMIDE	COC1=CC2=C(OC(NS(=O)(=O)C3=CC(Cl)=CC=C3Cl)=N2)C(=C1)C1=CC(N)=CC=C1
FBP1	DB07312	fructose-1,6-bisphosphatase 1	experimental	2,5-DICHLORO-N-(5-CHLORO-1,3-BENZOXAZOL-2-YL)BENZENESULFONAMIDE	ClC1=CC=C2OC(NS(=O)(=O)C3=CC(Cl)=CC=C3Cl)=NC2=C1
FBP1	DB07321	fructose-1,6-bisphosphatase 1	experimental	2,5-DICHLORO-N-[5-METHOXY-7-(6-METHOXYPYRIDIN-3-YL)-1,3-BENZOXAZOL-2-YL]BENZENESULFONAMIDE	COC1=CC2=C(OC(NS(=O)(=O)C3=CC(Cl)=CC=C3Cl)=N2)C(=C1)C1=CN=C(OC)C=C1
FBP1	DB08484	fructose-1,6-bisphosphatase 1	experimental	4-AMINO-N-[(2-SULFANYLETHYL)CARBAMOYL]BENZENESULFONAMIDE	NC1=CC=C(C=C1)S(=O)(=O)NC(=O)NCCS
FBP2	DB00121	fructose-1,6-bisphosphatase 2	approved; nutraceutical	Biotin	OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12
FBXW7	DB00877	F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase	approved; investigational	Sirolimus	CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1O
FDFT1	DB00630	farnesyl-diphosphate farnesyltransferase 1	approved	Alendronate	NCCCC(O)(P(O)(O)=O)P(O)(O)=O
FDFT1	DB00710	farnesyl-diphosphate farnesyltransferase 1	approved; investigational	Ibandronate	CCCCCN(C)CCC(O)(P(O)(O)=O)P(O)(O)=O
FDFT1	DB00282	farnesyl-diphosphate farnesyltransferase 1	approved	Pamidronate	NCCC(O)(P(O)(O)=O)P(O)(O)=O
FDFT1	DB00884	farnesyl-diphosphate farnesyltransferase 1	approved; investigational	Risedronate	OC(CC1=CN=CC=C1)(P(O)(O)=O)P(O)(O)=O
FDFT1	DB00399	farnesyl-diphosphate farnesyltransferase 1	approved	Zoledronate	OC(CN1C=CN=C1)(P(O)(O)=O)P(O)(O)=O
FDPS	DB00282	farnesyl diphosphate synthase	approved	Pamidronate	NCCC(O)(P(O)(O)=O)P(O)(O)=O
FDPS	DB00399	farnesyl diphosphate synthase	approved	Zoledronate	OC(CN1C=CN=C1)(P(O)(O)=O)P(O)(O)=O
FDPS	DB00630	farnesyl diphosphate synthase	approved	Alendronate	NCCCC(O)(P(O)(O)=O)P(O)(O)=O
FDPS	DB00710	farnesyl diphosphate synthase	approved; investigational	Ibandronate	CCCCCN(C)CCC(O)(P(O)(O)=O)P(O)(O)=O
FDPS	DB00884	farnesyl diphosphate synthase	approved; investigational	Risedronate	OC(CC1=CN=CC=C1)(P(O)(O)=O)P(O)(O)=O
FDPS	DB01785	farnesyl diphosphate synthase	experimental	Dimethylallyl Diphosphate	CC(C)=CCO[P@](O)(=O)OP(O)(O)=O
FDPS	DB02508	farnesyl diphosphate synthase	experimental	Isopentyl Pyrophosphate	CC(C)CCO[P@](O)(=O)OP(O)(O)=O
FDPS	DB02552	farnesyl diphosphate synthase	experimental	Geranyl Diphosphate	CC(C)=CCC\C(C)=C\CO[P@@](=O)(O)OP(=O)(O)O
FDPS	DB04714	farnesyl diphosphate synthase	experimental	ISOPENTENYL PYROPHOSPHATE	CC(=C)CCO[P@](O)(=O)OP(O)(O)=O
FDPS	DB07780	farnesyl diphosphate synthase	experimental	FARNESYL DIPHOSPHATE	CC(C)=CCC\C(C)=C\CC\C(C)=C\CO[P@@](=O)(O)OP(=O)(O)O
FDPS	DB07841	farnesyl diphosphate synthase	experimental	GERANYLGERANYL DIPHOSPHATE	CC(C)=CCC\C(C)=C/CC\C(C)=C\CC\C(C)=C\CO[P@@](O)(=O)OP(O)(O)=O
FDPS	DB00481	farnesyl diphosphate synthase	approved; investigational	Raloxifene	OC1=CC=C(C=C1)C1=C(C(=O)C2=CC=C(OCCN3CCCCC3)C=C2)C2=C(S1)C=C(O)C=C2
FECH	DB02659	ferrochelatase	experimental	Cholic Acid	C[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C
FECH	DB00145	ferrochelatase	approved; nutraceutical	Glycine	NCC(O)=O
FFAR1	DB00159	free fatty acid receptor 1	approved; nutraceutical	Icosapent	CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O
FHIT	DB02373	fragile histidine triad	experimental	Adenosine Monotungstate	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](CO[W](O)(O)=O)[C@H](O)[C@H]1O
FHIT	DB04173	fragile histidine triad	experimental	Fructose	OC[C@@H]1O[C@@](O)(CO)[C@H](O)[C@H]1O
FHIT	DB04389	fragile histidine triad	experimental	Ado-P-Ch2-P-Ps-Ado	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](CO[P@@](O)(=O)C[P@](O)(=O)O[P@](S)(=O)OC[C@@H]2O[C@H]([C@H](O)[C@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@H]1O
FMO1	DB00458	flavin containing monooxygenase 1	approved	Imipramine	CN(C)CCCN1C2=CC=CC=C2CCC2=CC=CC=C12
FMO1	DB00184	flavin containing monooxygenase 1	approved	Nicotine	CN1CCCC1C1=CN=CC=C1
FMO1	DB00675	flavin containing monooxygenase 1	approved	Tamoxifen	CC\C(=C(/C1=CC=CC=C1)C1=CC=C(OCCN(C)C)C=C1)C1=CC=CC=C1
FMO2	DB00675	flavin containing monooxygenase 2 (non-functional)	approved	Tamoxifen	CC\C(=C(/C1=CC=CC=C1)C1=CC=C(OCCN(C)C)C=C1)C1=CC=CC=C1
FMO3	DB00184	flavin containing monooxygenase 3	approved	Nicotine	CN1CCCC1C1=CN=CC=C1
FMO3	DB01098	flavin containing monooxygenase 3	approved	Rosuvastatin	CC(C)C1=NC(=NC(C2=CC=C(F)C=C2)=C1\C=C\[C@H](O)C[C@@H](O)CC(O)=O)N(C)S(=O)(=O)C
FMO3	DB00675	flavin containing monooxygenase 3	approved	Tamoxifen	CC\C(=C(/C1=CC=CC=C1)C1=CC=C(OCCN(C)C)C=C1)C1=CC=CC=C1
FMO4	DB00763	flavin containing monooxygenase 4	approved	Methimazole	CN1C=CNC1=S
FPGS	DB00142	folylpolyglutamate synthase	approved; nutraceutical	L-Glutamic Acid	N[C@@H](CCC(O)=O)C(O)=O
FPGS	DB00293	folylpolyglutamate synthase	approved; investigational	Raltitrexed	CN(CC1=CC2=C(NC(C)=NC2=O)C=C1)C1=CC=C(S1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
FPGS	DB00544	folylpolyglutamate synthase	approved	Fluorouracil	FC1=CNC(=O)NC1=O
FPGS	DB00650	folylpolyglutamate synthase	approved	Leucovorin	NC1=NC(=O)C2=C(NCC(CNC3=CC=C(C=C3)C(=O)N[C@H](CCC(O)=O)C(O)=O)N2C=O)N1
FPGS	DB00145	folylpolyglutamate synthase	approved; nutraceutical	Glycine	NCC(O)=O
FPGS	DB00133	folylpolyglutamate synthase	approved; nutraceutical	L-Serine	N[C@@H](CO)C(O)=O
FPGS	DB00515	folylpolyglutamate synthase	approved	Cisplatin	N[Pt](N)(Cl)Cl
FPGS	DB00252	folylpolyglutamate synthase	approved	Phenytoin	O=C1NC(=O)C(N1)(C1=CC=CC=C1)C1=CC=CC=C1
FPGS	DB00563	folylpolyglutamate synthase	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
FPGS	DB00642	folylpolyglutamate synthase	approved; investigational	Pemetrexed	NC1=NC(=O)C2=C(NC=C2CCC2=CC=C(C=C2)C(=O)N[C@H](CCC(O)=O)C(O)=O)N1
FSHB	DB00171	follicle stimulating hormone, beta polypeptide	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
FTCD	DB00114	formimidoyltransferase cyclodeaminase	nutraceutical	Pyridoxal Phosphate	CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O
FTCD	DB00116	formimidoyltransferase cyclodeaminase	approved; nutraceutical	Tetrahydrofolic acid	NC1=NC(=O)C2=C(NCC(CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)N2)N1
FTCD	DB00142	formimidoyltransferase cyclodeaminase	approved; nutraceutical	L-Glutamic Acid	N[C@@H](CCC(O)=O)C(O)=O
FTCD	DB03256	formimidoyltransferase cyclodeaminase	experimental	5-Formyl-5,6,7,8-Tetrahydrofolate	NC1=NC(=O)C2=C(NC[C@H](CNC3=CC=C(C=C3)C(=O)N[C@H](CCC(O)=O)C(O)=O)N2C=O)N1
FTCD	DB00117	formimidoyltransferase cyclodeaminase	approved; nutraceutical	L-Histidine	N[C@@H](CC1=CN=CN1)C(O)=O
FTH1	DB00563	ferritin, heavy polypeptide 1	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
FURIN	DB03600	furin (paired basic amino acid cleaving enzyme)	experimental	Decanoic Acid	CCCCCCCCCC(O)=O
G6PC	DB00121	glucose-6-phosphatase, catalytic subunit	approved; nutraceutical	Biotin	OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12
G6PD	DB01582	glucose-6-phosphate dehydrogenase	approved	Sulfamethazine	CC1=CC(C)=NC(NS(=O)(=O)C2=CC=C(N)C=C2)=N1
G6PD	DB00608	glucose-6-phosphate dehydrogenase	approved	Chloroquine	CCN(CC)CCCC(C)NC1=C2C=CC(Cl)=CC2=NC=C1
G6PD	DB00250	glucose-6-phosphate dehydrogenase	approved; investigational	Dapsone	NC1=CC=C(C=C1)S(=O)(=O)C1=CC=C(N)C=C1
G6PD	DB01033	glucose-6-phosphate dehydrogenase	approved	Mercaptopurine	S=C1N=CNC2=C1NC=N2
G6PD	DB00563	glucose-6-phosphate dehydrogenase	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
G6PD	DB00783	glucose-6-phosphate dehydrogenase	approved; investigational	Estradiol	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CC[C@@H]2O
G6PD	DB00675	glucose-6-phosphate dehydrogenase	approved	Tamoxifen	CC\C(=C(/C1=CC=CC=C1)C1=CC=C(OCCN(C)C)C=C1)C1=CC=CC=C1
G6PD	DB01087	glucose-6-phosphate dehydrogenase	approved	Primaquine	COC1=CC(NC(C)CCCN)=C2N=CC=CC2=C1
GAA	DB00284	glucosidase, alpha; acid	approved; investigational	Acarbose	C[C@H]1O[C@H](O[C@@H]2[C@@H](CO)O[C@H](O[C@@H]3[C@@H](CO)O[C@@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1N[C@H]1C=C(CO)[C@H](O)[C@H](O)[C@H]1O
GAA	DB00491	glucosidase, alpha; acid	approved	Miglitol	OCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO
GAD1	DB00114	glutamate decarboxylase 1 (brain, 67kDa)	nutraceutical	Pyridoxal Phosphate	CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O
GAD1	DB00142	glutamate decarboxylase 1 (brain, 67kDa)	approved; nutraceutical	L-Glutamic Acid	N[C@@H](CCC(O)=O)C(O)=O
GAD2	DB00142	glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)	approved; nutraceutical	L-Glutamic Acid	N[C@@H](CCC(O)=O)C(O)=O
GAD2	DB00114	glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)	nutraceutical	Pyridoxal Phosphate	CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O
GALE	DB01861	UDP-galactose-4-epimerase	experimental	Glucose-Uridine-C1,5'-Diphosphate	OC[C@@H]1O[C@H](O[P@](O)(=O)O[P@@](O)(=O)OC[C@@H]2O[C@H]([C@H](O)[C@H]2O)N2C=CC(=O)NC2=O)[C@@H](O)[C@H](O)[C@H]1O
GALE	DB01907	UDP-galactose-4-epimerase	experimental	Nicotinamide-Adenine-Dinucleotide	NC(=O)C1=CC=C[N+](=C1)[C@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@@H]1O
GALE	DB02196	UDP-galactose-4-epimerase	experimental	Uridine-Diphosphate-N-Acetylgalactosamine	CC(=O)N[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1O[P@](O)(=O)O[P@](O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=CC(=O)NC1=O
GALE	DB03095	UDP-galactose-4-epimerase	experimental	Tetramethylammonium Ion	C[N+](C)(C)C
GALE	DB03397	UDP-galactose-4-epimerase	experimental	Uridine-Diphosphate-N-Acetylglucosamine	CC(=O)N[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[P@](O)(=O)O[P@](O)(=O)OC[C@@H]1O[C@H]([C@H](O)[C@H]1O)N1C=CC(=O)NC1=O
GALE	DB03501	UDP-galactose-4-epimerase	experimental	Uridine Diphosphate Galactose	OC[C@@H]1O[C@H](O[P@](O)(=O)O[P@@](O)(=O)OC[C@@H]2O[C@H]([C@H](O)[C@H]2O)N2C=CC(=O)NC2=O)[C@@H](O)[C@H](O)[C@H]1O
GALE	DB04355	UDP-galactose-4-epimerase	experimental	Uridine-5'-Monophosphate Glucopyranosyl-Monophosphateester	OC[C@@H]1O[C@H](O[P@](O)(=O)O[P@@](O)(=O)OC[C@@H]2O[C@H]([C@H](O)[C@H]2O)N2C=CC(=O)NC2=O)[C@@H](O)[C@H](O)[C@H]1O
GALE	DB02421	UDP-galactose-4-epimerase	experimental	Uridine-5'-Diphosphate-Mannose	OC[C@@H]1O[C@H](O[P@](O)(=O)O[P@@](O)(=O)OC[C@@H]2O[C@H]([C@H](O)[C@H]2O)N2C=CC(=O)NC2=O)[C@@H](O)[C@H](O)[C@H]1O
GALE	DB02790	UDP-galactose-4-epimerase	experimental	Phenyl-Uridine-5'-Diphosphate	O[C@@H]1[C@@H](O)[C@@H](O[C@H]1CO[P@](O)(=O)O[P@@](O)(=O)OC1=CC=CC=C1)N1C=CC(=O)NC1=O
GALE	DB03435	UDP-galactose-4-epimerase	experimental	Uridine-5'-Diphosphate	O[C@@H]1[C@@H](O)[C@@H](O[C@H]1CO[P@](O)(=O)OP(O)(O)=O)N1C=CC(=O)NC1=O
GALE	DB04097	UDP-galactose-4-epimerase	experimental	Uridine-5'-Diphosphate-4-Deoxy-4-Fluoro-Alpha-D-Galactose	OC[C@@H]1O[C@H](O[P@](O)(=O)O[P@@](O)(=O)OC[C@@H]2O[C@H]([C@H](O)[C@H]2O)N2C=CC(=O)NC2=O)[C@@H](O)[C@H](O)[C@H]1F
GALK1	DB03431	galactokinase 1	experimental	Adenosine-5'-Diphosphate	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](CO[P@](O)(=O)OP(O)(O)=O)[C@H](O)[C@H]1O
GALK1	DB04395	galactokinase 1	experimental	Phosphoaminophosphonic Acid-Adenylate Ester	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](CO[P@](O)(=O)O[P@@](O)(=O)NP(O)(O)=O)[C@H](O)[C@H]1O
GALM	DB02379	galactose mutarotase (aldose 1-epimerase)	experimental	Beta-D-Glucose	OC[C@@H]1O[C@H](O)[C@@H](O)[C@H](O)[C@H]1O
GALM	DB03142	galactose mutarotase (aldose 1-epimerase)	experimental	Alpha-L-Arabinose	OC[C@@H]1O[C@@H](O)[C@H](O)[C@H]1O
GALM	DB03389	galactose mutarotase (aldose 1-epimerase)	experimental	alpha-D-Xylopyranose	O[C@@H]1CO[C@H](O)[C@H](O)[C@H]1O
GALM	DB03773	galactose mutarotase (aldose 1-epimerase)	experimental	6-Deoxy-Alpha-D-Glucose	C[C@@H]1O[C@H](O)[C@@H](O)[C@H](O)[C@H]1O
GALNT7	DB01033	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)	approved	Mercaptopurine	S=C1N=CNC2=C1NC=N2
GALNT7	DB00563	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
GALT	DB01861	galactose-1-phosphate uridylyltransferase	experimental	Glucose-Uridine-C1,5'-Diphosphate	OC[C@@H]1O[C@H](O[P@](O)(=O)O[P@@](O)(=O)OC[C@@H]2O[C@H]([C@H](O)[C@H]2O)N2C=CC(=O)NC2=O)[C@@H](O)[C@H](O)[C@H]1O
GALT	DB03435	galactose-1-phosphate uridylyltransferase	experimental	Uridine-5'-Diphosphate	O[C@@H]1[C@@H](O)[C@@H](O[C@H]1CO[P@](O)(=O)OP(O)(O)=O)N1C=CC(=O)NC1=O
GALT	DB03685	galactose-1-phosphate uridylyltransferase	experimental	Uridine-5'-Monophosphate	O[C@@H]1[C@@H](O)[C@@H](O[C@H]1COP(O)(O)=O)N1C=CC(=O)NC1=O
GAMT	DB00148	guanidinoacetate N-methyltransferase	approved; nutraceutical	Creatine	CN(CC(O)=O)C(N)=N
GAMT	DB00536	guanidinoacetate N-methyltransferase	approved	Guanidine	NC(N)=N
GAMT	DB01752	guanidinoacetate N-methyltransferase	experimental	S-Adenosyl-L-Homocysteine	N[C@@H](CCSC[C@@H]1O[C@H]([C@H](O)[C@H]1O)N1C=NC2=C1N=CN=C2N)C(O)=O
GAMT	DB02751	guanidinoacetate N-methyltransferase	experimental	N-[Amino(Imino)Methyl]Glycine	NC(=N)NCC(O)=O
GAMT	DB00145	guanidinoacetate N-methyltransferase	approved; nutraceutical	Glycine	NCC(O)=O
GAMT	DB00125	guanidinoacetate N-methyltransferase	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
GAPDH	DB00157	glyceraldehyde-3-phosphate dehydrogenase	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
GAPDH	DB01907	glyceraldehyde-3-phosphate dehydrogenase	experimental	Nicotinamide-Adenine-Dinucleotide	NC(=O)C1=CC=C[N+](=C1)[C@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@@H]1O
GAPDH	DB02059	glyceraldehyde-3-phosphate dehydrogenase	experimental	Adenosine-5-Diphosphoribose	NC1=C2N=CN([C@@H]3O[C@H](CO[P@@](O)(=O)O[P@@](O)(=O)OC[C@H]4O[C@H](O)[C@H](O)[C@@H]4O)[C@@H](O)[C@H]3O)C2=NC=N1
GAPDH	DB03893	glyceraldehyde-3-phosphate dehydrogenase	experimental	Thionicotinamide-Adenine-Dinucleotide	NC(=S)C1=CC=C[N+](=C1)[C@@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@@H]2O[C@H]([C@H](O)[C@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@H]1O
GAPDH	DB07347	glyceraldehyde-3-phosphate dehydrogenase	experimental	4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE	NCCC1=CC=C(C=C1)S(F)(=O)=O
GAPDH	DB02263	glyceraldehyde-3-phosphate dehydrogenase	experimental	Glyceraldehyde-3-Phosphate	O[C@H](COP(O)(O)=O)C=O
GAPDH	DB00269	glyceraldehyde-3-phosphate dehydrogenase	approved	Chlorotrianisene	COC1=CC=C(C=C1)C(Cl)=C(C1=CC=C(OC)C=C1)C1=CC=C(OC)C=C1
GAPDH	DB00286	glyceraldehyde-3-phosphate dehydrogenase	approved	Conjugated Estrogens	[Na+].C[C@]12CC[C@H]3[C@@H](CCC4=CC(OS([O-])(=O)=O)=CC=C34)[C@@H]1CCC2=O
GAPDH	DB00890	glyceraldehyde-3-phosphate dehydrogenase	approved	Dienestrol	CC=C(C(=CC)C1=CC=C(O)C=C1)C1=CC=C(O)C=C1
GAPDH	DB00255	glyceraldehyde-3-phosphate dehydrogenase	approved	Diethylstilbestrol	CCC(=C(CC)C1=CC=C(O)C=C1)C1=CC=C(O)C=C1
GAPDH	DB00783	glyceraldehyde-3-phosphate dehydrogenase	approved; investigational	Estradiol	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CC[C@@H]2O
GAPDH	DB00655	glyceraldehyde-3-phosphate dehydrogenase	approved	Estrone	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CCC2=O
GAPDH	DB00977	glyceraldehyde-3-phosphate dehydrogenase	approved	Ethinyl Estradiol	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CC[C@@]2(O)C#C
GAPDHS	DB00157	glyceraldehyde-3-phosphate dehydrogenase, spermatogenic	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
GAPDHS	DB01907	glyceraldehyde-3-phosphate dehydrogenase, spermatogenic	experimental	Nicotinamide-Adenine-Dinucleotide	NC(=O)C1=CC=C[N+](=C1)[C@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@@H]1O
GAPDHS	DB02205	glyceraldehyde-3-phosphate dehydrogenase, spermatogenic	experimental	6-(1,1-Dimethylallyl)-2-(1-Hydroxy-1-Methylethyl)-2,3-Dihydro-7h-Furo[3,2-G]Chromen-7-One	CC(C)(O)[C@@H]1CC2=C(O1)C=C1OC(=O)C(=CC1=C2)C(C)(C)C=C
GAPDHS	DB03331	glyceraldehyde-3-phosphate dehydrogenase, spermatogenic	experimental	N-Naphthalen-1-Ylmethyl-2'-[3,5-Dimethoxybenzamido]-2'-Deoxy-Adenosine	COC1=CC(=CC(OC)=C1)C(=O)N[C@@H]1[C@@H](O)[C@H](CO)O[C@H]1N1C=NC2=C1N=CN=C2NCC1=CC=CC2=C1C=CC=C2
GAPDHS	DB04477	glyceraldehyde-3-phosphate dehydrogenase, spermatogenic	experimental	N-1,2,3,4-Tetrahydronaphth-1-Yl-2'-[3,5-Dimethoxybenzamido]-2'-Deoxy-Adenosine	COC1=CC(=CC(OC)=C1)C(=O)N[C@@H]1[C@@H](O)[C@H](CO)O[C@H]1N1C=NC2=C1N=CN=C2N[C@@H]1CCCC2=CC=CC=C12
GART	DB00642	phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase	approved; investigational	Pemetrexed	NC1=NC(=O)C2=C(NC=C2CCC2=CC=C(C=C2)C(=O)N[C@H](CCC(O)=O)C(O)=O)N1
GART	DB02236	phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase	experimental	Glycinamide Ribonucleotide	NCC(=O)N[C@@H]1O[C@@H](COP([O-])([O-])=O)[C@H](O)[C@H]1O
GART	DB03546	phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase	experimental	10-CF3C(OH)2-DDACTHF	N[C@@H]1N[C@H](N)[C@@H](CCC[C@@H](C2=CC=C(C=C2)C(=O)N[C@H](CCC(O)=O)C(O)=O)C(O)(O)C(F)(F)F)C(=O)N1
GART	DB00145	phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase	approved; nutraceutical	Glycine	NCC(O)=O
GART	DB00130	phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase	approved; nutraceutical; investigational	L-Glutamine	N[C@@H](CCC(N)=O)C(O)=O
GART	DB00563	phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
GATA4	DB00864	GATA binding protein 4	approved; investigational	Tacrolimus	CO[C@@H]1C[C@@H](CC[C@H]1O)\C=C(/C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H]([C@H](C[C@H]2C)OC)[C@H](C[C@@H](C)C\C(C)=C\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]1C)OC
GATM	DB00129	glycine amidinotransferase (L-arginine:glycine amidinotransferase)	approved; nutraceutical	L-Ornithine	NCCC[C@H](N)C(O)=O
GATM	DB00145	glycine amidinotransferase (L-arginine:glycine amidinotransferase)	approved; nutraceutical	Glycine	NCC(O)=O
GATM	DB02068	glycine amidinotransferase (L-arginine:glycine amidinotransferase)	experimental	Delta-Amino Valeric Acid	[NH3+]CCCCC(O)=O
GATM	DB02530	glycine amidinotransferase (L-arginine:glycine amidinotransferase)	experimental	Gamma(Amino)-Butyric Acid	NCCCC(O)=O
GATM	DB04185	glycine amidinotransferase (L-arginine:glycine amidinotransferase)	experimental	Norvaline	CCC[C@H](N)C(O)=O
GATM	DB04454	glycine amidinotransferase (L-arginine:glycine amidinotransferase)	experimental	Alpha-Aminobutyric Acid	CC[C@@H](N)C(O)=O
GATM	DB00125	glycine amidinotransferase (L-arginine:glycine amidinotransferase)	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
GATM	DB00515	glycine amidinotransferase (L-arginine:glycine amidinotransferase)	approved	Cisplatin	N[Pt](N)(Cl)Cl
GBA	DB03106	glucosidase, beta, acid	experimental	Myo-Inositol	O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O
GBA	DB03740	glucosidase, beta, acid	experimental	2-(Acetylamino)-2-Deoxy-a-D-Glucopyranose	CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@H](O)[C@@H]1O
GBA	DB08283	glucosidase, beta, acid	experimental	(2R,3R,4R,5S)-2-(HYDROXYMETHYL)-1-NONYLPIPERIDINE-3,4,5-TRIOL	CCCCCCCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO
GBE1	DB01033	glucan (1,4-alpha-), branching enzyme 1	approved	Mercaptopurine	S=C1N=CNC2=C1NC=N2
GBE1	DB00563	glucan (1,4-alpha-), branching enzyme 1	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
GC	DB00136	group-specific component (vitamin D binding protein)	approved; nutraceutical	Calcitriol	C[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2C(CCC[C@]12C)=CC=C1C[C@@H](O)C[C@H](O)C1=C
GCAT	DB00114	glycine C-acetyltransferase	nutraceutical	Pyridoxal Phosphate	CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O
GCAT	DB00145	glycine C-acetyltransferase	approved; nutraceutical	Glycine	NCC(O)=O
GCDH	DB03147	glutaryl-CoA dehydrogenase	experimental	Flavin-Adenine Dinucleotide	CC1=CC2=C(C=C1C)N(C[C@H](O)[C@H](O)[C@H](O)CO[P@](O)(=O)O[P@@](O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC3=C1N=CN=C3N)C1=NC(=O)NC(=O)C1=N2
GCDH	DB03245	glutaryl-CoA dehydrogenase	experimental	S-4-Nitrobutyryl-Coa	CC(C)(CO[P@](O)(=O)O[P@@](O)(=O)OC[C@@H]1O[C@H]([C@H](O)[C@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N)[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)CCC[N](O)=O
GCDH	DB00123	glutaryl-CoA dehydrogenase	approved; nutraceutical	L-Lysine	NCCCC[C@H](N)C(O)=O
GCK	DB02379	glucokinase (hexokinase 4)	experimental	Beta-D-Glucose	OC[C@@H]1O[C@H](O)[C@@H](O)[C@H](O)[C@H]1O
GCK	DB07358	glucokinase (hexokinase 4)	experimental	2-amino-N-(4-methyl-1,3-thiazol-2-yl)-5-[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]benzamide	CN1C=NN=C1SC1=CC=C(N)C(=C1)C(=O)NC1=NC(C)=CS1
GCK	DB07359	glucokinase (hexokinase 4)	experimental	3-[(4-fluorophenyl)sulfanyl]-N-(4-methyl-1,3-thiazol-2-yl)-6-[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]pyridine-2-carboxamide	CN1C=NN=C1SC1=NC(C(=O)NC2=NC(C)=CS2)=C(SC2=CC=C(F)C=C2)C=C1
GCK	DB08118	glucokinase (hexokinase 4)	experimental	2-(methylamino)-N-(4-methyl-1,3-thiazol-2-yl)-5-[(4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl]benzamide	CNC1=C(C=C(SC2=NN=CN2C)C=C1)C(=O)NC1=NC(C)=CS1
GCK	DB08210	glucokinase (hexokinase 4)	experimental	2-AMINO-4-FLUORO-5-[(1-METHYL-1H-IMIDAZOL-2-YL)SULFANYL]-N-(1,3-THIAZOL-2-YL)BENZAMIDE	CN1C=CN=C1SC1=CC(C(=O)NC2=NC=CS2)=C(N)C=C1F
GCLC	DB00142	glutamate-cysteine ligase, catalytic subunit	approved; nutraceutical	L-Glutamic Acid	N[C@@H](CCC(O)=O)C(O)=O
GCLC	DB00151	glutamate-cysteine ligase, catalytic subunit	approved; nutraceutical	L-Cysteine	N[C@@H](CS)C(O)=O
GCLC	DB00515	glutamate-cysteine ligase, catalytic subunit	approved	Cisplatin	N[Pt](N)(Cl)Cl
GCLC	DB00143	glutamate-cysteine ligase, catalytic subunit	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
GCLM	DB00142	glutamate-cysteine ligase, modifier subunit	approved; nutraceutical	L-Glutamic Acid	N[C@@H](CCC(O)=O)C(O)=O
GCLM	DB00151	glutamate-cysteine ligase, modifier subunit	approved; nutraceutical	L-Cysteine	N[C@@H](CS)C(O)=O
GCLM	DB00515	glutamate-cysteine ligase, modifier subunit	approved	Cisplatin	N[Pt](N)(Cl)Cl
GCLM	DB00143	glutamate-cysteine ligase, modifier subunit	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
GFER	DB00260	growth factor, augmenter of liver regeneration	approved	Cycloserine	NC1CONC1=O
GFER	DB01993	growth factor, augmenter of liver regeneration	experimental	N-(5'-Phosphopyridoxyl)-D-Alanine	C[C@@H](NCC1=C(O)C(C)=NC=C1COP(O)(O)=O)C(O)=O
GFER	DB02142	growth factor, augmenter of liver regeneration	experimental	Pyridoxamine-5'-Phosphate	CC1=NC=C(COP(O)(O)=O)C(CN)=C1O
GFER	DB03097	growth factor, augmenter of liver regeneration	experimental	Pmp-Hydroxyisoxazole, Pyridoxamine-5-Phosphate-Hydroxyisoxazole	CC1=NC=C(COP(O)(O)=O)C(CNC2=CON=C2O)=C1O
GFER	DB03327	growth factor, augmenter of liver regeneration	experimental	{1-[(3-Hydroxy-Methyl-5-Phosphonooxy-Methyl-Pyridin-4-Ylmethyl)-Amino]-Ethyl}-Phosphonic Acid	C[C@@H](NCC1=C(O)C(C)=NC=C1COP(O)(O)=O)P(O)(O)=O
GFER	DB03579	growth factor, augmenter of liver regeneration	experimental	Pyridoxyl-N,O-Cycloserylamide-5-Monophosphate	CC1=NC=C(COP(O)(O)=O)C(CN[C@@H]2CONC2=O)=C1O
GFER	DB03766	growth factor, augmenter of liver regeneration	experimental	Propanoic Acid	CCC(O)=O
GFER	DB03801	growth factor, augmenter of liver regeneration	experimental	Lysine Nz-Carboxylic Acid	N[C@@H](CCCCNC(O)=O)C(O)=O
GFER	DB04467	growth factor, augmenter of liver regeneration	experimental	Pyridoxyl-Alanine-5-Phosphate	C[C@@H](NCC1=C(O)C(C)=NC=C1COP(O)(O)=O)C(O)=O
GGCX	DB00142	gamma-glutamyl carboxylase	approved; nutraceutical	L-Glutamic Acid	N[C@@H](CCC(O)=O)C(O)=O
GGCX	DB00170	gamma-glutamyl carboxylase	approved; nutraceutical	Menadione	CC1=CC(=O)C2=CC=CC=C2C1=O
GGCX	DB01022	gamma-glutamyl carboxylase	approved	Phytonadione	CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC\C(C)=C\CC1=C(C)C(=O)C2=C(C=CC=C2)C1=O
GGCX	DB01125	gamma-glutamyl carboxylase	approved	Anisindione	COC1=CC=C(C=C1)C1C(=O)C2=CC=CC=C2C1=O
GGCX	DB00682	gamma-glutamyl carboxylase	approved	Warfarin	CC(=O)CC(C1=CC=CC=C1)C1=C(O)OC2=CC=CC=C2C1=O
GGPS1	DB00399	geranylgeranyl diphosphate synthase 1	approved	Zoledronate	OC(CN1C=CN=C1)(P(O)(O)=O)P(O)(O)=O
GGPS1	DB02552	geranylgeranyl diphosphate synthase 1	experimental	Geranyl Diphosphate	CC(C)=CCC\C(C)=C\CO[P@@](=O)(O)OP(=O)(O)O
GGPS1	DB04695	geranylgeranyl diphosphate synthase 1	experimental	FARNESYL THIOPYROPHOSPHATE	CC(C)=CCC\C(C)=C\CC\C(C)=C/CS[P@@](=O)(O)OP(O)(=O)O
GGPS1	DB04714	geranylgeranyl diphosphate synthase 1	experimental	ISOPENTENYL PYROPHOSPHATE	CC(=C)CCO[P@](O)(=O)OP(O)(O)=O
GGPS1	DB06830	geranylgeranyl diphosphate synthase 1	experimental	(1-HYDROXYHEPTANE-1,1-DIYL)BIS(PHOSPHONIC ACID)	CCCCCCC(O)(P(O)(O)=O)P(O)(O)=O
GGPS1	DB06931	geranylgeranyl diphosphate synthase 1	experimental	(1-HYDROXYNONANE-1,1-DIYL)BIS(PHOSPHONIC ACID)	CCCCCCCCC(O)(P(O)(O)=O)P(O)(O)=O
GGPS1	DB07221	geranylgeranyl diphosphate synthase 1	experimental	(2,2-DIPHOSPHONOETHYL)(DODECYL)DIMETHYLPHOSPHONIUM	CCCCCCCCCCCC[P+](C)(C)CC(P(O)(O)=O)P(O)(O)=O
GGPS1	DB07410	geranylgeranyl diphosphate synthase 1	experimental	[2-(3-DIBENZOFURAN-4-YL-PHENYL)-1-HYDROXY-1-PHOSPHONO-ETHYL]-PHOSPHONIC ACID	OC(CC1=CC(=CC=C1)C1=CC=CC2=C1OC1=C2C=CC=C1)(P(O)(O)=O)P(O)(O)=O
GGPS1	DB07780	geranylgeranyl diphosphate synthase 1	experimental	FARNESYL DIPHOSPHATE	CC(C)=CCC\C(C)=C\CC\C(C)=C\CO[P@@](=O)(O)OP(=O)(O)O
GGPS1	DB07841	geranylgeranyl diphosphate synthase 1	experimental	GERANYLGERANYL DIPHOSPHATE	CC(C)=CCC\C(C)=C/CC\C(C)=C\CC\C(C)=C\CO[P@@](O)(=O)OP(O)(O)=O
GGPS1	DB07873	geranylgeranyl diphosphate synthase 1	experimental	(1-HYDROXYDODECANE-1,1-DIYL)BIS(PHOSPHONIC ACID)	CCCCCCCCCCCC(O)(P(O)(O)=O)P(O)(O)=O
GGPS1	DB08529	geranylgeranyl diphosphate synthase 1	experimental	(6E,11E)-HEPTADECA-6,11-DIENE-9,9-DIYLBIS(PHOSPHONIC ACID)	CCCCC\C=C\CC(C\C=C\CCCCC)(P(O)(O)=O)P(O)(O)=O
GGT1	DB00143	gamma-glutamyltransferase 1	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
GGT5	DB00143	gamma-glutamyltransferase 5	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
GGT5	DB00145	gamma-glutamyltransferase 5	approved; nutraceutical	Glycine	NCC(O)=O
GIP	DB00363	gastric inhibitory polypeptide	approved	Clozapine	CN1CCN(CC1)C1=NC2=CC(Cl)=CC=C2NC2=CC=CC=C12
GLA	DB02944	galactosidase, alpha	experimental	Alpha-D-Mannose	OC[C@@H]1O[C@H](O)[C@@H](O)[C@H](O)[C@H]1O
GLDC	DB00114	glycine dehydrogenase (decarboxylating)	nutraceutical	Pyridoxal Phosphate	CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O
GLDC	DB00145	glycine dehydrogenase (decarboxylating)	approved; nutraceutical	Glycine	NCC(O)=O
GLO1	DB00143	glyoxalase I	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
GLO1	DB00328	glyoxalase I	approved; investigational	Indomethacin	COC1=CC2=C(C=C1)N(C(=O)C1=CC=C(Cl)C=C1)C(C)=C2CC(O)=O
GLO1	DB03130	glyoxalase I	experimental	S-P-Nitrobenzyloxycarbonylglutathione	N[C@@H](CCC(=O)N[C@H](CS[C@H](O)OCC1=CC=C(C=C1)[N+]([O-])=O)C(=O)NCC(O)=O)C(O)=O
GLO1	DB03330	glyoxalase I	experimental	S-(N-Hydroxy-N-Iodophenylcarbamoyl)Glutathione	N[C@@H](CCC(=O)N[C@H](CS[C@H](O)N(O)C1=CC=C(I)C=C1)C(=O)NCC(O)=O)C(O)=O
GLO1	DB03345	glyoxalase I	experimental	Beta-Mercaptoethanol	OCCS
GLO1	DB03602	glyoxalase I	experimental	S-Benzyl-Glutathione	N[C@@H](CCC(=O)N[C@H](CSCC1=CC=CC=C1)C(=O)NCC(O)=O)C(O)=O
GLO1	DB04132	glyoxalase I	experimental	S-Hexylglutathione	CCCCCCSC[C@@H](NC(=O)CC[C@H]([NH3+])C(O)=O)C(=O)NCC(O)=O
GLO1	DB08179	glyoxalase I	experimental	methyl 4-(2,3-dihydroxy-5-methylphenoxy)-2-hydroxy-6-methylbenzoate	COC(=O)C1=C(C)C=C(OC2=C(O)C(O)=CC(C)=C2)C=C1O
GLRX	DB00143	glutaredoxin (thioltransferase)	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
GLS	DB00142	glutaminase	approved; nutraceutical	L-Glutamic Acid	N[C@@H](CCC(O)=O)C(O)=O
GLS	DB00149	glutaminase	approved; nutraceutical	L-Leucine	CC(C)CC(N)C(O)=O
GLS	DB00130	glutaminase	approved; nutraceutical; investigational	L-Glutamine	N[C@@H](CCC(N)=O)C(O)=O
GLS2	DB00142	glutaminase 2 (liver, mitochondrial)	approved; nutraceutical	L-Glutamic Acid	N[C@@H](CCC(O)=O)C(O)=O
GLS2	DB00130	glutaminase 2 (liver, mitochondrial)	approved; nutraceutical; investigational	L-Glutamine	N[C@@H](CCC(N)=O)C(O)=O
GLUD1	DB00142	glutamate dehydrogenase 1	approved; nutraceutical	L-Glutamic Acid	N[C@@H](CCC(O)=O)C(O)=O
GLUD1	DB00157	glutamate dehydrogenase 1	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
GLUD1	DB00756	glutamate dehydrogenase 1	approved	Hexachlorophene	OC1=C(CC2=C(O)C(Cl)=CC(Cl)=C2Cl)C(Cl)=C(Cl)C=C1Cl
GLUD1	DB01907	glutamate dehydrogenase 1	experimental	Nicotinamide-Adenine-Dinucleotide	NC(=O)C1=CC=C[N+](=C1)[C@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@@H]1O
GLUD1	DB03431	glutamate dehydrogenase 1	experimental	Adenosine-5'-Diphosphate	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](CO[P@](O)(=O)OP(O)(O)=O)[C@H](O)[C@H]1O
GLUD1	DB04137	glutamate dehydrogenase 1	experimental	Guanosine-5'-Triphosphate	NC1=NC2=C(N=CN2[C@@H]2O[C@@H](CO[P@](O)(=O)O[P@@](O)(=O)OP(O)(O)=O)[C@H](O)[C@H]2O)C(=O)N1
GLUD1	DB00130	glutamate dehydrogenase 1	approved; nutraceutical; investigational	L-Glutamine	N[C@@H](CCC(N)=O)C(O)=O
GLUD2	DB00142	glutamate dehydrogenase 2	approved; nutraceutical	L-Glutamic Acid	N[C@@H](CCC(O)=O)C(O)=O
GLUD2	DB00157	glutamate dehydrogenase 2	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
GLUD2	DB01907	glutamate dehydrogenase 2	experimental	Nicotinamide-Adenine-Dinucleotide	NC(=O)C1=CC=C[N+](=C1)[C@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@@H]1O
GLUL	DB02663	glutamate-ammonia ligase	experimental	2-Amino-4-(Hydroxymethyl-Phosphinyl)Butanoic Acid	C[P@@](O)(=O)CC[C@@H](N)C(O)=O
GLUL	DB03431	glutamate-ammonia ligase	experimental	Adenosine-5'-Diphosphate	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](CO[P@](O)(=O)OP(O)(O)=O)[C@H](O)[C@H]1O
GLUL	DB00130	glutamate-ammonia ligase	approved; nutraceutical; investigational	L-Glutamine	N[C@@H](CCC(N)=O)C(O)=O
GLUL	DB00142	glutamate-ammonia ligase	approved; nutraceutical	L-Glutamic Acid	N[C@@H](CCC(O)=O)C(O)=O
GM2A	DB02261	GM2 ganglioside activator	experimental	Platelet Activating Factor	CCCCCCCCCCCCCCCCOC[C@H](CO[P@@]([O-])(=O)OCC[N+](C)(C)C)OC(C)=O
GM2A	DB03633	GM2 ganglioside activator	experimental	Lpc-Ether	CCCCCCCCCCCCCCCCCCOC[C@@H](O)CO[P@@](O)(=O)OCC[N+](C)(C)C
GM2A	DB04660	GM2 ganglioside activator	experimental	Glycerylphosphorylcholine	C[N+](C)(C)CCO[P@](O)(=O)OC[C@H](O)CO
GM2A	DB08231	GM2 ganglioside activator	experimental	MYRISTIC ACID	CCCCCCCCCCCCCC(O)=O
GMDS	DB02547	GDP-mannose 4,6-dehydratase	experimental	Guanosine-5'-Diphosphate-Rhamnose	C[C@@H]1O[C@H](O[P@](O)(=O)O[P@@](O)(=O)OC[C@@H]2O[C@H]([C@H](O)[C@H]2O)N2C=NC3=C2N=C(N)NC3=O)[C@@H](O)[C@H](O)[C@H]1O
GMDS	DB04315	GDP-mannose 4,6-dehydratase	experimental	Guanosine-5'-Diphosphate	NC1=NC2=C(N=CN2[C@@H]2O[C@@H](CO[P@](O)(=O)OP(O)(O)=O)[C@H](O)[C@H]2O)C(=O)N1
GMPR	DB01972	guanosine monophosphate reductase	experimental	Guanosine-5'-Monophosphate	NC1=NC2=C(N=CN2[C@@H]2O[C@@H](COP(O)(O)=O)[C@H](O)[C@H]2O)C(=O)N1
GMPS	DB00142	guanine monphosphate synthase	approved; nutraceutical	L-Glutamic Acid	N[C@@H](CCC(O)=O)C(O)=O
GMPS	DB02212	guanine monphosphate synthase	experimental	Pyrophosphate 2-	O[P@]([O-])(=O)O[P@@](O)([O-])=O
GMPS	DB04272	guanine monphosphate synthase	experimental	Citric Acid	OC(=O)CC(O)(CC(O)=O)C(O)=O
GMPS	DB00130	guanine monphosphate synthase	approved; nutraceutical; investigational	L-Glutamine	N[C@@H](CCC(N)=O)C(O)=O
GNA11	DB00125	guanine nucleotide binding protein (G protein), alpha 11 (Gq class)	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
GNA11	DB00435	guanine nucleotide binding protein (G protein), alpha 11 (Gq class)	approved	Nitric Oxide	[N]=O
GNAI1	DB00945	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1	approved	Acetylsalicylic acid	CC(=O)OC1=CC=CC=C1C(O)=O
GNAI1	DB00125	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
GNAI1	DB00435	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1	approved	Nitric Oxide	[N]=O
GNAI1	DB00396	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1	approved	Progesterone	CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C
GNAI1	DB00171	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
GNAI1	DB01064	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1	approved	Isoproterenol	CC(C)NCC(O)C1=CC(O)=C(O)C=C1
GNAI1	DB00938	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1	approved	Salmeterol	OCC1=C(O)C=CC(=C1)C(O)CNCCCCCCOCCCCC1=CC=CC=C1
GNAI2	DB00125	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
GNAI2	DB00435	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	approved	Nitric Oxide	[N]=O
GNAI2	DB00938	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	approved	Salmeterol	OCC1=C(O)C=CC(=C1)C(O)CNCCCCCCOCCCCC1=CC=CC=C1
GNAQ	DB00864	guanine nucleotide binding protein (G protein), q polypeptide	approved; investigational	Tacrolimus	CO[C@@H]1C[C@@H](CC[C@H]1O)\C=C(/C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H]([C@H](C[C@H]2C)OC)[C@H](C[C@@H](C)C\C(C)=C\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]1C)OC
GNAQ	DB00171	guanine nucleotide binding protein (G protein), q polypeptide	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
GNAQ	DB00131	guanine nucleotide binding protein (G protein), q polypeptide	approved; nutraceutical	Adenosine monophosphate	NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
GNAQ	DB00125	guanine nucleotide binding protein (G protein), q polypeptide	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
GNAQ	DB00155	guanine nucleotide binding protein (G protein), q polypeptide	approved; nutraceutical	L-Citrulline	N[C@@H](CCCNC(N)=O)C(O)=O
GNAQ	DB00435	guanine nucleotide binding protein (G protein), q polypeptide	approved	Nitric Oxide	[N]=O
GNAQ	DB00608	guanine nucleotide binding protein (G protein), q polypeptide	approved	Chloroquine	CCN(CC)CCCC(C)NC1=C2C=CC(Cl)=CC2=NC=C1
GNAS	DB02587	GNAS complex locus	experimental	Forskolin	CC(=O)O[C@H]1[C@@H](O)[C@H]2C(C)(C)CC[C@H](O)[C@]2(C)[C@@]2(O)C(=O)C[C@@](C)(O[C@]12C)C=C
GNAS	DB06843	GNAS complex locus	experimental	2',5'-DIDEOXY-ADENOSINE 3'-MONOPHOSPHATE	C[C@H]1O[C@H](C[C@@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N
GNAS	DB00515	GNAS complex locus	approved	Cisplatin	N[Pt](N)(Cl)Cl
GNAS	DB00544	GNAS complex locus	approved	Fluorouracil	FC1=CNC(=O)NC1=O
GNAS	DB00394	GNAS complex locus	approved	Beclomethasone	C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
GNAS	DB00443	GNAS complex locus	approved	Betamethasone	C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
GNAS	DB01222	GNAS complex locus	approved; investigational	Budesonide	CCC[C@H]1O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO
GNAS	DB01410	GNAS complex locus	approved; investigational	Ciclesonide	CC(C)C(=O)OCC(=O)[C@@]12OC(O[C@@H]1C[C@H]1[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@]21C)C1CCCCC1
GNAS	DB01260	GNAS complex locus	approved; investigational	Desonide	CC1(C)O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO
GNAS	DB01234	GNAS complex locus	approved; investigational	Dexamethasone	C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
GNAS	DB00180	GNAS complex locus	approved; investigational	Flunisolide	CC1(C)O[C@@H]2C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO
GNAS	DB00588	GNAS complex locus	approved; investigational	Fluticasone Propionate	CCC(=O)O[C@@]1([C@H](C)C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)C(=O)SCF
GNAS	DB00741	GNAS complex locus	approved	Hydrocortisone	C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
GNAS	DB00959	GNAS complex locus	approved	Methylprednisolone	C[C@H]1C[C@H]2[C@@H]3CC[C@](O)(C(=O)CO)[C@@]3(C)C[C@H](O)[C@@H]2[C@@]2(C)C=CC(=O)C=C12
GNAS	DB00764	GNAS complex locus	approved	Mometasone	C[C@@H]1C[C@H]2C3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CCl
GNAS	DB01384	GNAS complex locus	approved	Paramethasone	C[C@@H]1C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
GNAS	DB00860	GNAS complex locus	approved	Prednisolone	C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
GNAS	DB00635	GNAS complex locus	approved	Prednisone	C[C@]12CC(=O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
GNAS	DB00896	GNAS complex locus	approved	Rimexolone	CCC(=O)[C@@]1(C)[C@H](C)CC2C3CCC4=CC(=O)C=C[C@]4(C)C3[C@@H](O)C[C@]12C
GNAS	DB00620	GNAS complex locus	approved	Triamcinolone	C[C@]12C[C@H](O)[C@@]3(F)[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1C[C@@H](O)[C@]2(O)C(=O)CO
GNAS	DB00125	GNAS complex locus	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
GNAS	DB00155	GNAS complex locus	approved; nutraceutical	L-Citrulline	N[C@@H](CCCNC(N)=O)C(O)=O
GNAS	DB00435	GNAS complex locus	approved	Nitric Oxide	[N]=O
GNAS	DB00988	GNAS complex locus	approved	Dopamine	NCCC1=CC(O)=C(O)C=C1
GNAS	DB00131	GNAS complex locus	approved; nutraceutical	Adenosine monophosphate	NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
GNAS	DB00171	GNAS complex locus	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
GNAS	DB00770	GNAS complex locus	approved; investigational	Alprostadil	CCCCC[C@H](O)C=C[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(O)=O
GNAS	DB00668	GNAS complex locus	approved	Epinephrine	CNC[C@H](O)C1=CC(O)=C(O)C=C1
GNAS	DB00396	GNAS complex locus	approved	Progesterone	CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C
GNAS	DB01064	GNAS complex locus	approved	Isoproterenol	CC(C)NCC(O)C1=CC(O)=C(O)C=C1
GNAS	DB01105	GNAS complex locus	illicit; approved; withdrawn; investigational	Sibutramine	CC(C)CC(N(C)C)C1(CCC1)C1=CC=C(Cl)C=C1
GNAS	DB00938	GNAS complex locus	approved	Salmeterol	OCC1=C(O)C=CC(=C1)C(O)CNCCCCCCOCCCCC1=CC=CC=C1
GNB1	DB07752	guanine nucleotide binding protein (G protein), beta polypeptide 1	experimental	FARNESYL	C\C=C(/C)CC\C=C(/C)CCC=C(C)C
GNB1	DB00945	guanine nucleotide binding protein (G protein), beta polypeptide 1	approved	Acetylsalicylic acid	CC(=O)OC1=CC=CC=C1C(O)=O
GNB1	DB00394	guanine nucleotide binding protein (G protein), beta polypeptide 1	approved	Beclomethasone	C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
GNB1	DB00443	guanine nucleotide binding protein (G protein), beta polypeptide 1	approved	Betamethasone	C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
GNB1	DB01222	guanine nucleotide binding protein (G protein), beta polypeptide 1	approved; investigational	Budesonide	CCC[C@H]1O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO
GNB1	DB01410	guanine nucleotide binding protein (G protein), beta polypeptide 1	approved; investigational	Ciclesonide	CC(C)C(=O)OCC(=O)[C@@]12OC(O[C@@H]1C[C@H]1[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@]21C)C1CCCCC1
GNB1	DB01260	guanine nucleotide binding protein (G protein), beta polypeptide 1	approved; investigational	Desonide	CC1(C)O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO
GNB1	DB01234	guanine nucleotide binding protein (G protein), beta polypeptide 1	approved; investigational	Dexamethasone	C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
GNB1	DB00180	guanine nucleotide binding protein (G protein), beta polypeptide 1	approved; investigational	Flunisolide	CC1(C)O[C@@H]2C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO
GNB1	DB00588	guanine nucleotide binding protein (G protein), beta polypeptide 1	approved; investigational	Fluticasone Propionate	CCC(=O)O[C@@]1([C@H](C)C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)C(=O)SCF
GNB1	DB00741	guanine nucleotide binding protein (G protein), beta polypeptide 1	approved	Hydrocortisone	C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
GNB1	DB00959	guanine nucleotide binding protein (G protein), beta polypeptide 1	approved	Methylprednisolone	C[C@H]1C[C@H]2[C@@H]3CC[C@](O)(C(=O)CO)[C@@]3(C)C[C@H](O)[C@@H]2[C@@]2(C)C=CC(=O)C=C12
GNB1	DB00764	guanine nucleotide binding protein (G protein), beta polypeptide 1	approved	Mometasone	C[C@@H]1C[C@H]2C3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CCl
GNB1	DB01384	guanine nucleotide binding protein (G protein), beta polypeptide 1	approved	Paramethasone	C[C@@H]1C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
GNB1	DB00860	guanine nucleotide binding protein (G protein), beta polypeptide 1	approved	Prednisolone	C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
GNB1	DB00635	guanine nucleotide binding protein (G protein), beta polypeptide 1	approved	Prednisone	C[C@]12CC(=O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
GNB1	DB00896	guanine nucleotide binding protein (G protein), beta polypeptide 1	approved	Rimexolone	CCC(=O)[C@@]1(C)[C@H](C)CC2C3CCC4=CC(=O)C=C[C@]4(C)C3[C@@H](O)C[C@]12C
GNB1	DB00620	guanine nucleotide binding protein (G protein), beta polypeptide 1	approved	Triamcinolone	C[C@]12C[C@H](O)[C@@]3(F)[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1C[C@@H](O)[C@]2(O)C(=O)CO
GNB1	DB00125	guanine nucleotide binding protein (G protein), beta polypeptide 1	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
GNB1	DB00155	guanine nucleotide binding protein (G protein), beta polypeptide 1	approved; nutraceutical	L-Citrulline	N[C@@H](CCCNC(N)=O)C(O)=O
GNB1	DB00435	guanine nucleotide binding protein (G protein), beta polypeptide 1	approved	Nitric Oxide	[N]=O
GNB1	DB00988	guanine nucleotide binding protein (G protein), beta polypeptide 1	approved	Dopamine	NCCC1=CC(O)=C(O)C=C1
GNB1	DB00171	guanine nucleotide binding protein (G protein), beta polypeptide 1	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
GNB1	DB00131	guanine nucleotide binding protein (G protein), beta polypeptide 1	approved; nutraceutical	Adenosine monophosphate	NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
GNB1	DB00396	guanine nucleotide binding protein (G protein), beta polypeptide 1	approved	Progesterone	CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C
GNB3	DB00575	guanine nucleotide binding protein (G protein), beta polypeptide 3	approved	Clonidine	ClC1=CC=CC(Cl)=C1NC1=NCCN1
GNB3	DB00363	guanine nucleotide binding protein (G protein), beta polypeptide 3	approved	Clozapine	CN1CCN(CC1)C1=NC2=CC(Cl)=CC=C2NC2=CC=CC=C12
GNB3	DB00540	guanine nucleotide binding protein (G protein), beta polypeptide 3	approved	Nortriptyline	CNCCC=C1C2=CC=CC=C2CCC2=CC=CC=C12
GNB3	DB00918	guanine nucleotide binding protein (G protein), beta polypeptide 3	approved; investigational	Almotriptan	CN(C)CCC1=CNC2=C1C=C(CS(=O)(=O)N1CCCC1)C=C2
GNB3	DB00334	guanine nucleotide binding protein (G protein), beta polypeptide 3	approved; investigational	Olanzapine	CN1CCN(CC1)C1=C2C=C(C)SC2=NC2=CC=CC=C2N1
GNB3	DB00216	guanine nucleotide binding protein (G protein), beta polypeptide 3	approved; investigational	Eletriptan	CN1CCC[C@@H]1CC1=CNC2=C1C=C(CCS(=O)(=O)C1=CC=CC=C1)C=C2
GNB3	DB00952	guanine nucleotide binding protein (G protein), beta polypeptide 3	approved; investigational	Naratriptan	CNS(=O)(=O)CCC1=CC2=C(NC=C2C2CCN(C)CC2)C=C1
GNB3	DB00953	guanine nucleotide binding protein (G protein), beta polypeptide 3	approved	Rizatriptan	CN(C)CCC1=CNC2=C1C=C(CN1C=NC=N1)C=C2
GNB3	DB00669	guanine nucleotide binding protein (G protein), beta polypeptide 3	approved; investigational	Sumatriptan	CNS(=O)(=O)CC1=CC2=C(NC=C2CCN(C)C)C=C1
GNB3	DB00315	guanine nucleotide binding protein (G protein), beta polypeptide 3	approved; investigational	Zolmitriptan	CN(C)CCC1=CNC2=C1C=C(C[C@@H]1COC(=O)N1)C=C2
GNB3	DB00203	guanine nucleotide binding protein (G protein), beta polypeptide 3	approved; investigational	Sildenafil	CCCC1=NN(C)C2=C1NC(=NC2=O)C1=C(OCC)C=CC(=C1)S(=O)(=O)N1CCN(C)CC1
GNB3	DB01076	guanine nucleotide binding protein (G protein), beta polypeptide 3	approved	Atorvastatin	CC(C)C1=C(C(=O)NC2=CC=CC=C2)C(=C(N1CC[C@@H](O)C[C@@H](O)CC(O)=O)C1=CC=C(F)C=C1)C1=CC=CC=C1
GNB3	DB01095	guanine nucleotide binding protein (G protein), beta polypeptide 3	approved	Fluvastatin	CC(C)N1C(\C=C\[C@H](O)C[C@H](O)CC(O)=O)=C(C2=CC=C(F)C=C2)C2=CC=CC=C12
GNB3	DB00227	guanine nucleotide binding protein (G protein), beta polypeptide 3	approved; investigational	Lovastatin	CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12
GNB3	DB00175	guanine nucleotide binding protein (G protein), beta polypeptide 3	approved	Pravastatin	CC[C@H](C)C(=O)O[C@H]1C[C@H](O)C=C2C=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC(O)=O)[C@@H]12
GNB3	DB01098	guanine nucleotide binding protein (G protein), beta polypeptide 3	approved	Rosuvastatin	CC(C)C1=NC(=NC(C2=CC=C(F)C=C2)=C1\C=C\[C@H](O)C[C@@H](O)CC(O)=O)N(C)S(=O)(=O)C
GNB3	DB00641	guanine nucleotide binding protein (G protein), beta polypeptide 3	approved	Simvastatin	CCC(C)(C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CCC3C[C@@H](O)CC(=O)O3)[C@@H]12
GNB3	DB00177	guanine nucleotide binding protein (G protein), beta polypeptide 3	approved; investigational	Valsartan	CCCCC(=O)N(CC1=CC=C(C=C1)C1=CC=CC=C1C1=NNN=N1)[C@@H](C(C)C)C(O)=O
GNB3	DB01392	guanine nucleotide binding protein (G protein), beta polypeptide 3	approved	Yohimbine	COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCC4=C(NC5=CC=CC=C45)[C@@H]3C[C@H]12
GNB3	DB01105	guanine nucleotide binding protein (G protein), beta polypeptide 3	illicit; approved; withdrawn; investigational	Sibutramine	CC(C)CC(N(C)C)C1(CCC1)C1=CC=C(Cl)C=C1
GNB3	DB00999	guanine nucleotide binding protein (G protein), beta polypeptide 3	approved	Hydrochlorothiazide	NS(=O)(=O)C1=C(Cl)C=C2NCNS(=O)(=O)C2=C1
GNB3	DB00335	guanine nucleotide binding protein (G protein), beta polypeptide 3	approved	Atenolol	CC(C)NCC(O)COC1=CC=C(CC(N)=O)C=C1
GNB5	DB00125	guanine nucleotide binding protein (G protein), beta 5	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
GNB5	DB00435	guanine nucleotide binding protein (G protein), beta 5	approved	Nitric Oxide	[N]=O
GNG10	DB01033	guanine nucleotide binding protein (G protein), gamma 10	approved	Mercaptopurine	S=C1N=CNC2=C1NC=N2
GNG10	DB00563	guanine nucleotide binding protein (G protein), gamma 10	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
GNG2	DB01159	guanine nucleotide binding protein (G protein), gamma 2	approved	Halothane	FC(F)(F)C(Cl)Br
GNG2	DB00125	guanine nucleotide binding protein (G protein), gamma 2	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
GNG2	DB00435	guanine nucleotide binding protein (G protein), gamma 2	approved	Nitric Oxide	[N]=O
GNGT1	DB07752	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1	experimental	FARNESYL	C\C=C(/C)CC\C=C(/C)CCC=C(C)C
GNGT1	DB00945	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1	approved	Acetylsalicylic acid	CC(=O)OC1=CC=CC=C1C(O)=O
GNGT1	DB00394	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1	approved	Beclomethasone	C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
GNGT1	DB00443	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1	approved	Betamethasone	C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
GNGT1	DB01222	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1	approved; investigational	Budesonide	CCC[C@H]1O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO
GNGT1	DB01410	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1	approved; investigational	Ciclesonide	CC(C)C(=O)OCC(=O)[C@@]12OC(O[C@@H]1C[C@H]1[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@]21C)C1CCCCC1
GNGT1	DB01260	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1	approved; investigational	Desonide	CC1(C)O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO
GNGT1	DB01234	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1	approved; investigational	Dexamethasone	C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
GNGT1	DB00180	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1	approved; investigational	Flunisolide	CC1(C)O[C@@H]2C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO
GNGT1	DB00588	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1	approved; investigational	Fluticasone Propionate	CCC(=O)O[C@@]1([C@H](C)C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)C(=O)SCF
GNGT1	DB00741	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1	approved	Hydrocortisone	C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
GNGT1	DB00959	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1	approved	Methylprednisolone	C[C@H]1C[C@H]2[C@@H]3CC[C@](O)(C(=O)CO)[C@@]3(C)C[C@H](O)[C@@H]2[C@@]2(C)C=CC(=O)C=C12
GNGT1	DB00764	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1	approved	Mometasone	C[C@@H]1C[C@H]2C3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CCl
GNGT1	DB01384	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1	approved	Paramethasone	C[C@@H]1C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
GNGT1	DB00860	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1	approved	Prednisolone	C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
GNGT1	DB00635	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1	approved	Prednisone	C[C@]12CC(=O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
GNGT1	DB00896	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1	approved	Rimexolone	CCC(=O)[C@@]1(C)[C@H](C)CC2C3CCC4=CC(=O)C=C[C@]4(C)C3[C@@H](O)C[C@]12C
GNGT1	DB00620	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1	approved	Triamcinolone	C[C@]12C[C@H](O)[C@@]3(F)[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1C[C@@H](O)[C@]2(O)C(=O)CO
GNGT1	DB00125	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
GNGT1	DB00155	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1	approved; nutraceutical	L-Citrulline	N[C@@H](CCCNC(N)=O)C(O)=O
GNGT1	DB00435	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1	approved	Nitric Oxide	[N]=O
GNGT1	DB00988	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1	approved	Dopamine	NCCC1=CC(O)=C(O)C=C1
GNGT1	DB00171	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
GNGT1	DB00131	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1	approved; nutraceutical	Adenosine monophosphate	NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
GNGT1	DB00396	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1	approved	Progesterone	CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C
GNMT	DB00118	glycine N-methyltransferase	approved; nutraceutical	S-Adenosylmethionine	C[S+](CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C(N)N=CN=C12
GNMT	DB00145	glycine N-methyltransferase	approved; nutraceutical	Glycine	NCC(O)=O
GNMT	DB01752	glycine N-methyltransferase	experimental	S-Adenosyl-L-Homocysteine	N[C@@H](CCSC[C@@H]1O[C@H]([C@H](O)[C@H]1O)N1C=NC2=C1N=CN=C2N)C(O)=O
GNMT	DB04272	glycine N-methyltransferase	experimental	Citric Acid	OC(=O)CC(O)(CC(O)=O)C(O)=O
GNPDA1	DB02379	glucosamine-6-phosphate deaminase 1	experimental	Beta-D-Glucose	OC[C@@H]1O[C@H](O)[C@@H](O)[C@H](O)[C@H]1O
GNPDA1	DB02445	glucosamine-6-phosphate deaminase 1	experimental	2-Deoxy-2-Amino Glucitol-6-Phosphate	N[C@H](CO)[C@H](O)[C@@H](O)[C@H](O)COP(O)(O)=O
GNPDA1	DB03951	glucosamine-6-phosphate deaminase 1	experimental	16g	CC(=O)N[C@H]1[C@H](O)O[C@H](COP(O)(O)=O)[C@H](O)[C@@H]1O
GOT1	DB00114	glutamic-oxaloacetic transaminase 1, soluble	nutraceutical	Pyridoxal Phosphate	CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O
GOT1	DB00128	glutamic-oxaloacetic transaminase 1, soluble	approved; nutraceutical	L-Aspartic Acid	N[C@@H](CC(O)=O)C(O)=O
GOT1	DB00142	glutamic-oxaloacetic transaminase 1, soluble	approved; nutraceutical	L-Glutamic Acid	N[C@@H](CCC(O)=O)C(O)=O
GOT1	DB00151	glutamic-oxaloacetic transaminase 1, soluble	approved; nutraceutical	L-Cysteine	N[C@@H](CS)C(O)=O
GOT1	DB04299	glutamic-oxaloacetic transaminase 1, soluble	experimental	Maleic Acid	OC(=O)\C=C\C(O)=O
GOT1	DB00121	glutamic-oxaloacetic transaminase 1, soluble	approved; nutraceutical	Biotin	OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12
GOT1	DB00130	glutamic-oxaloacetic transaminase 1, soluble	approved; nutraceutical; investigational	L-Glutamine	N[C@@H](CCC(N)=O)C(O)=O
GOT2	DB00114	glutamic-oxaloacetic transaminase 2, mitochondrial	nutraceutical	Pyridoxal Phosphate	CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O
GOT2	DB00128	glutamic-oxaloacetic transaminase 2, mitochondrial	approved; nutraceutical	L-Aspartic Acid	N[C@@H](CC(O)=O)C(O)=O
GOT2	DB00142	glutamic-oxaloacetic transaminase 2, mitochondrial	approved; nutraceutical	L-Glutamic Acid	N[C@@H](CCC(O)=O)C(O)=O
GOT2	DB02783	glutamic-oxaloacetic transaminase 2, mitochondrial	experimental	4'-Deoxy-4'-Acetylyamino-Pyridoxal-5'-Phosphate	CC1=NC=C(COP(O)(O)=O)C(CNOCC(O)=O)=C1O
GOT2	DB00121	glutamic-oxaloacetic transaminase 2, mitochondrial	approved; nutraceutical	Biotin	OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12
GOT2	DB00130	glutamic-oxaloacetic transaminase 2, mitochondrial	approved; nutraceutical; investigational	L-Glutamine	N[C@@H](CCC(N)=O)C(O)=O
GPC1	DB00435	glypican 1	approved	Nitric Oxide	[N]=O
GPD1	DB00157	glycerol-3-phosphate dehydrogenase 1 (soluble)	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
GPHN	DB01942	gephyrin	experimental	Formic Acid	OC=O
GPHN	DB03766	gephyrin	experimental	Propanoic Acid	CCC(O)=O
GPI	DB02007	glucose-6-phosphate isomerase	experimental	Alpha-D-Glucose-6-Phosphate	O[C@H]1O[C@@H](COP(O)(O)=O)[C@H](O)[C@@H](O)[C@@H]1O
GPI	DB02076	glucose-6-phosphate isomerase	experimental	6-Phosphogluconic Acid	O[C@H](COP(O)(O)=O)[C@H](O)[C@H](O)[C@@H](O)C(O)=O
GPI	DB02093	glucose-6-phosphate isomerase	experimental	5-Phospho-D-Arabinohydroxamic Acid	ONC(=O)[C@H](O)[C@H](O)[C@@H](O)COP(O)(O)=O
GPI	DB02548	glucose-6-phosphate isomerase	experimental	Sorbitol 6-phosphate	OC[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)COP(O)(O)=O
GPI	DB03042	glucose-6-phosphate isomerase	experimental	5-Phosphoarabinonic Acid	O[C@H](COP(O)(O)=O)[C@H](O)[C@H](O)C(O)=O
GPI	DB03581	glucose-6-phosphate isomerase	experimental	Glucose-6-Phosphate	O[C@H](COP(O)(O)=O)[C@H](O)[C@H](O)[C@@H](O)C=O
GPI	DB03937	glucose-6-phosphate isomerase	experimental	Erythose-4-Phosphate	O[C@@H](COP(O)(O)=O)[C@@H](O)C=O
GPI	DB04493	glucose-6-phosphate isomerase	experimental	Fructose-6-Phosphate	OC[C@]1(O)O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O
GPI	DB00121	glucose-6-phosphate isomerase	approved; nutraceutical	Biotin	OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12
GPT	DB00114	glutamic-pyruvate transaminase (alanine aminotransferase)	nutraceutical	Pyridoxal Phosphate	CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O
GPT	DB00142	glutamic-pyruvate transaminase (alanine aminotransferase)	approved; nutraceutical	L-Glutamic Acid	N[C@@H](CCC(O)=O)C(O)=O
GPT	DB00160	glutamic-pyruvate transaminase (alanine aminotransferase)	approved; nutraceutical	L-Alanine	C[C@H](N)C(O)=O
GPT	DB00780	glutamic-pyruvate transaminase (alanine aminotransferase)	approved	Phenelzine	NNCCC1=CC=CC=C1
GPT	DB04898	glutamic-pyruvate transaminase (alanine aminotransferase)	approved; withdrawn; investigational	Ximelagatran	CCOC(=O)CN[C@@H](C(=O)N1CC[C@H]1C(=O)NCC1=CC=C(C=C1)C(\N)=N\O)C1CCCCC1
GPT2	DB00114	glutamic pyruvate transaminase (alanine aminotransferase) 2	nutraceutical	Pyridoxal Phosphate	CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O
GPT2	DB00142	glutamic pyruvate transaminase (alanine aminotransferase) 2	approved; nutraceutical	L-Glutamic Acid	N[C@@H](CCC(O)=O)C(O)=O
GPT2	DB00160	glutamic pyruvate transaminase (alanine aminotransferase) 2	approved; nutraceutical	L-Alanine	C[C@H](N)C(O)=O
GPT2	DB00780	glutamic pyruvate transaminase (alanine aminotransferase) 2	approved	Phenelzine	NNCCC1=CC=CC=C1
GPX1	DB00143	glutathione peroxidase 1	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
GPX1	DB01694	glutathione peroxidase 1	experimental	D-tartaric acid	O[C@@H]([C@@H](O)C(O)=O)C(O)=O
GPX1	DB01942	glutathione peroxidase 1	experimental	Formic Acid	OC=O
GPX1	DB01975	glutathione peroxidase 1	experimental	AMPCPR	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](CO[P@@](O)(=O)C[P@](O)(=O)OC[C@H]2O[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H]1O
GPX1	DB02059	glutathione peroxidase 1	experimental	Adenosine-5-Diphosphoribose	NC1=C2N=CN([C@@H]3O[C@H](CO[P@@](O)(=O)O[P@@](O)(=O)OC[C@H]4O[C@H](O)[C@H](O)[C@@H]4O)[C@@H](O)[C@H]3O)C2=NC=N1
GPX1	DB03148	glutathione peroxidase 1	experimental	Phosphomethylphosphonic Acid Adenosyl Ester	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](CO[P@@](O)(=O)CP(O)(O)=O)[C@H](O)[C@H]1O
GPX1	DB01992	glutathione peroxidase 1	experimental	Coenzyme A	CC(C)(CO[P@](O)(=O)O[P@@](O)(=O)OC[C@@H]1O[C@H]([C@H](O)[C@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N)[C@@H](O)C(=O)NCCC(=O)NCCS
GPX1	DB03014	glutathione peroxidase 1	experimental	Heme	CC1=C(CCC(O)=O)C2=CC3=[N+]4C(=CC5=C(C=C)C(C)=C6C=C7C(C=C)=C(C)C8=[N+]7[Fe@]4(N2C1=C8)N56)C(C)=C3CCC(O)=O
GPX1	DB03766	glutathione peroxidase 1	experimental	Propanoic Acid	CCC(O)=O
GPX1	DB03247	glutathione peroxidase 1	experimental	Riboflavin Monophosphate	CC1=CC2=C(C=C1C)N(C[C@@H](O)[C@@H](O)[C@H](O)COP(O)(O)=O)C1=NC(=O)NC(=O)C1=N2
GPX1	DB03382	glutathione peroxidase 1	experimental	S-Oxy Cysteine	N[C@@H](C[S]=O)C(O)=O
GPX1	DB03661	glutathione peroxidase 1	experimental	Cysteinesulfonic Acid	N[C@@H](CS(O)(=O)=O)C(O)=O
GPX1	DB04580	glutathione peroxidase 1	experimental	1-Methyl-2-quinolone	CN1C(=O)C=CC2=CC=CC=C12
GPX1	DB04605	glutathione peroxidase 1	experimental	5-Aminoisoquinoline	NC1=CC=CC2=C1C=CN=C2
GPX1	DB00515	glutathione peroxidase 1	approved	Cisplatin	N[Pt](N)(Cl)Cl
GPX1	DB00171	glutathione peroxidase 1	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
GPX1	DB01205	glutathione peroxidase 1	approved	Flumazenil	CCOC(=O)C1=C2CN(C)C(=O)C3=C(C=CC(F)=C3)N2C=N1
GPX1	DB00997	glutathione peroxidase 1	approved; investigational	Doxorubicin	COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3O[C@H]3C[C@H](N)[C@H](O)[C@H](C)O3)C(=O)CO)C(O)=C1C2=O
GPX1	DB00783	glutathione peroxidase 1	approved; investigational	Estradiol	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CC[C@@H]2O
GPX1	DB00675	glutathione peroxidase 1	approved	Tamoxifen	CC\C(=C(/C1=CC=CC=C1)C1=CC=C(OCCN(C)C)C=C1)C1=CC=CC=C1
GPX2	DB00143	glutathione peroxidase 2 (gastrointestinal)	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
GPX2	DB00515	glutathione peroxidase 2 (gastrointestinal)	approved	Cisplatin	N[Pt](N)(Cl)Cl
GPX3	DB00143	glutathione peroxidase 3 (plasma)	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
GPX3	DB00515	glutathione peroxidase 3 (plasma)	approved	Cisplatin	N[Pt](N)(Cl)Cl
GPX4	DB00143	glutathione peroxidase 4	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
GPX5	DB00143	glutathione peroxidase 5 (epididymal androgen-related protein)	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
GPX5	DB00515	glutathione peroxidase 5 (epididymal androgen-related protein)	approved	Cisplatin	N[Pt](N)(Cl)Cl
GPX6	DB00143	glutathione peroxidase 6 (olfactory)	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
GPX6	DB00515	glutathione peroxidase 6 (olfactory)	approved	Cisplatin	N[Pt](N)(Cl)Cl
GPX7	DB00143	glutathione peroxidase 7	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
GPX7	DB00515	glutathione peroxidase 7	approved	Cisplatin	N[Pt](N)(Cl)Cl
GRHPR	DB00145	glyoxylate reductase/hydroxypyruvate reductase	approved; nutraceutical	Glycine	NCC(O)=O
GRHPR	DB00160	glyoxylate reductase/hydroxypyruvate reductase	approved; nutraceutical	L-Alanine	C[C@H](N)C(O)=O
GSR	DB00143	glutathione reductase	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
GSR	DB00157	glutathione reductase	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
GSR	DB00262	glutathione reductase	approved	Carmustine	ClCCNC(=O)N(CCCl)N=O
GSR	DB01644	glutathione reductase	experimental	3,6-Dihydroxy-Xanthene-9-Propionic Acid	OC(=O)CCC1C2=CC=C(O)C=C2OC2=C1C=CC(O)=C2
GSR	DB01907	glutathione reductase	experimental	Nicotinamide-Adenine-Dinucleotide	NC(=O)C1=CC=C[N+](=C1)[C@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@@H]1O
GSR	DB02153	glutathione reductase	experimental	3-Sulfinoalanine	N[C@@H](C[S@@](O)=O)C(O)=O
GSR	DB02553	glutathione reductase	experimental	Glutathionylspermidine Disulfide	NCCCCNCCCNC(=O)CNC(=O)[C@@H](CSSC[C@@H](NC(=O)CC[C@@H](N)C(O)=O)C(=O)NCC(=O)NCCCNCCCCN)NC(=O)CC[C@H](N)C(O)=O
GSR	DB02895	glutathione reductase	experimental	3-(Prop-2-Ene-1-Sulfinyl)-Propene-1-Thiol	S\C=C\C[S@](=O)CC=C
GSR	DB03147	glutathione reductase	experimental	Flavin-Adenine Dinucleotide	CC1=CC2=C(C=C1C)N(C[C@H](O)[C@H](O)[C@H](O)CO[P@](O)(=O)O[P@@](O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC3=C1N=CN=C3N)C1=NC(=O)NC(=O)C1=N2
GSR	DB03310	glutathione reductase	experimental	Oxidized Glutathione Disulfide	N[C@H](CCC(=O)N[C@H](CSSC[C@@H](NC(=O)CC[C@@H](N)C(O)=O)C(=O)NCC(O)=O)C(=O)NCC(O)=O)C(O)=O
GSR	DB03867	glutathione reductase	experimental	Meta-Nitro-Tyrosine	N[C@@H](CC1=CC=C(O)C(=C1)[N+]([O-])=O)C(O)=O
GSR	DB07393	glutathione reductase	experimental	2-(2-PHENYL-3-PYRIDIN-2-YL-4,5,6,7-TETRAHYDRO-2H-ISOPHOSPHINDOL-1-YL)PYRIDINE	C1CCC2=C(P(C(=C2C1)C1=NC=CC=C1)C1=CC=CC=C1)C1=NC=CC=C1
GSR	DB07714	glutathione reductase	experimental	6-(3-METHYL-1,4-DIOXO-1,4-DIHYDRONAPHTHALEN-2-YL)HEXANOIC ACID	CC1=C(CCCCCC(O)=O)C(=O)C2=CC=CC=C2C1=O
GSR	DB00515	glutathione reductase	approved	Cisplatin	N[Pt](N)(Cl)Cl
GSS	DB00143	glutathione synthetase	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
GSS	DB00145	glutathione synthetase	approved; nutraceutical	Glycine	NCC(O)=O
GSS	DB00151	glutathione synthetase	approved; nutraceutical	L-Cysteine	N[C@@H](CS)C(O)=O
GSS	DB03408	glutathione synthetase	experimental	Gamma-Glutamylcysteine	N[C@@H](CCC(=O)N[C@H](CS)C(O)=O)C(O)=O
GSS	DB03431	glutathione synthetase	experimental	Adenosine-5'-Diphosphate	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](CO[P@](O)(=O)OP(O)(O)=O)[C@H](O)[C@H]1O
GSS	DB04395	glutathione synthetase	experimental	Phosphoaminophosphonic Acid-Adenylate Ester	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](CO[P@](O)(=O)O[P@@](O)(=O)NP(O)(O)=O)[C@H](O)[C@H]1O
GSS	DB00515	glutathione synthetase	approved	Cisplatin	N[Pt](N)(Cl)Cl
GSS	DB01033	glutathione synthetase	approved	Mercaptopurine	S=C1N=CNC2=C1NC=N2
GSS	DB00563	glutathione synthetase	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
GSTA1	DB00143	glutathione S-transferase alpha 1	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
GSTA1	DB01915	glutathione S-transferase alpha 1	experimental	S-Hydroxycysteine	N[C@@H](CSO)C(O)=O
GSTA1	DB02486	glutathione S-transferase alpha 1	experimental	2-Hydroxyethyl Disulfide	OCCSSCCO
GSTA1	DB02943	glutathione S-transferase alpha 1	experimental	N-(4-Aminobutanoyl)-S-(4-Methoxybenzyl)-L-Cysteinylglycine	COC1=CC=C(CSC[C@@H](NC(=O)CCCN)C(=O)NCC(O)=O)C=C1
GSTA1	DB03003	glutathione S-transferase alpha 1	experimental	Glutathione Sulfonic Acid	N[C@@H](CCC(=O)N[C@H](CS(O)(=O)=O)C(=O)NCC(O)=O)C(O)=O
GSTA1	DB03602	glutathione S-transferase alpha 1	experimental	S-Benzyl-Glutathione	N[C@@H](CCC(=O)N[C@H](CSCC1=CC=CC=C1)C(=O)NCC(O)=O)C(O)=O
GSTA1	DB04132	glutathione S-transferase alpha 1	experimental	S-Hexylglutathione	CCCCCCSC[C@@H](NC(=O)CC[C@H]([NH3+])C(O)=O)C(=O)NCC(O)=O
GSTA1	DB04572	glutathione S-transferase alpha 1	approved	Thiotepa	S=P(N1CC1)(N1CC1)N1CC1
GSTA1	DB00682	glutathione S-transferase alpha 1	approved	Warfarin	CC(=O)CC(C1=CC=CC=C1)C1=C(O)OC2=CC=CC=C2C1=O
GSTA1	DB00993	glutathione S-transferase alpha 1	approved	Azathioprine	CN1C=NC(=C1SC1=NC=NC2=C1NC=N2)[N+]([O-])=O
GSTA1	DB01033	glutathione S-transferase alpha 1	approved	Mercaptopurine	S=C1N=CNC2=C1NC=N2
GSTA1	DB00515	glutathione S-transferase alpha 1	approved	Cisplatin	N[Pt](N)(Cl)Cl
GSTA1	DB00291	glutathione S-transferase alpha 1	approved	Chlorambucil	OC(=O)CCCC1=CC=C(C=C1)N(CCCl)CCCl
GSTA1	DB00997	glutathione S-transferase alpha 1	approved; investigational	Doxorubicin	COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3O[C@H]3C[C@H](N)[C@H](O)[C@H](C)O3)C(=O)CO)C(O)=C1C2=O
GSTA1	DB00773	glutathione S-transferase alpha 1	approved	Etoposide	COC1=CC(=CC(OC)=C1O)[C@H]1[C@@H]2[C@H](COC2=O)[C@H](O[C@@H]2O[C@@H]3CO[C@@H](C)O[C@H]3[C@H](O)[C@H]2O)C2=CC3=C(OCO3)C=C12
GSTA1	DB01204	glutathione S-transferase alpha 1	approved; investigational	Mitoxantrone	OCCNCCNC1=C2C(=O)C3=C(O)C=CC(O)=C3C(=O)C2=C(NCCNCCO)C=C1
GSTA1	DB00541	glutathione S-transferase alpha 1	approved; investigational	Vincristine	CC[C@]1(O)C[C@H]2CN(C1)CCC1=C(NC3=CC=CC=C13)[C@@](C2)(C(=O)OC)C1=C(OC)C=C2N(C=O)[C@@H]3[C@]4(CCN5CC=C[C@](CC)([C@@H]45)[C@@H](OC(C)=O)[C@]3(O)C(=O)OC)C2=C1
GSTA1	DB00531	glutathione S-transferase alpha 1	approved; investigational	Cyclophosphamide	ClCCN(CCCl)P1(=O)NCCCO1
GSTA1	DB01008	glutathione S-transferase alpha 1	approved; investigational	Busulfan	CS(=O)(=O)OCCCCOS(C)(=O)=O
GSTA1	DB01101	glutathione S-transferase alpha 1	approved; investigational	Capecitabine	CCCCCOC(=O)NC1=NC(=O)N(C=C1F)[C@@H]1O[C@H](C)[C@@H](O)[C@H]1O
GSTA1	DB00762	glutathione S-transferase alpha 1	approved; investigational	Irinotecan	CCC1=C2CN3C(=CC4=C(COC(=O)[C@]4(O)CC)C3=O)C2=NC2=C1C=C(OC(=O)N1CCC(CC1)N1CCCCC1)C=C2
GSTA1	DB00526	glutathione S-transferase alpha 1	approved; investigational	Oxaliplatin	O=C1O[Pt]2(N[C@@H]3CCCC[C@H]3N2)OC1=O
GSTA1	DB01026	glutathione S-transferase alpha 1	approved; investigational	Ketoconazole	CC(=O)N1CCN(CC1)C1=CC=C(OC[C@@H]2CO[C@](CN3C=CN=C3)(O2)C2=C(Cl)C=C(Cl)C=C2)C=C1
GSTA1	DB01110	glutathione S-transferase alpha 1	approved; investigational	Miconazole	ClC1=CC(Cl)=C(COC(CN2C=CN=C2)C2=C(Cl)C=C(Cl)C=C2)C=C1
GSTA2	DB00143	glutathione S-transferase alpha 2	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
GSTA2	DB00608	glutathione S-transferase alpha 2	approved	Chloroquine	CCN(CC)CCCC(C)NC1=C2C=CC(Cl)=CC2=NC=C1
GSTA2	DB00515	glutathione S-transferase alpha 2	approved	Cisplatin	N[Pt](N)(Cl)Cl
GSTA2	DB01248	glutathione S-transferase alpha 2	approved; investigational	Docetaxel	CC(=O)O[C@@]12CO[C@@H]1C[C@H](O)[C@]1(C)[C@@H]2[C@H](OC(=O)C2=CC=CC=C2)[C@]2(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C3=CC=CC=C3)C(C)=C([C@@H](O)C1=O)C2(C)C
GSTA2	DB00993	glutathione S-transferase alpha 2	approved	Azathioprine	CN1C=NC(=C1SC1=NC=NC2=C1NC=N2)[N+]([O-])=O
GSTA2	DB01033	glutathione S-transferase alpha 2	approved	Mercaptopurine	S=C1N=CNC2=C1NC=N2
GSTA2	DB01026	glutathione S-transferase alpha 2	approved; investigational	Ketoconazole	CC(=O)N1CCN(CC1)C1=CC=C(OC[C@@H]2CO[C@](CN3C=CN=C3)(O2)C2=C(Cl)C=C(Cl)C=C2)C=C1
GSTA2	DB01110	glutathione S-transferase alpha 2	approved; investigational	Miconazole	ClC1=CC(Cl)=C(COC(CN2C=CN=C2)C2=C(Cl)C=C(Cl)C=C2)C=C1
GSTA3	DB00143	glutathione S-transferase alpha 3	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
GSTA3	DB04521	glutathione S-transferase alpha 3	experimental	GSHNA	CCCCC[C@H]1O[C@@H](O)C[C@@H]1SC[C@@H](NC(=O)CC[C@H](N)C(O)=O)C(=O)NCC(O)=O
GSTA3	DB00515	glutathione S-transferase alpha 3	approved	Cisplatin	N[Pt](N)(Cl)Cl
GSTA3	DB01248	glutathione S-transferase alpha 3	approved; investigational	Docetaxel	CC(=O)O[C@@]12CO[C@@H]1C[C@H](O)[C@]1(C)[C@@H]2[C@H](OC(=O)C2=CC=CC=C2)[C@]2(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C3=CC=CC=C3)C(C)=C([C@@H](O)C1=O)C2(C)C
GSTA4	DB00143	glutathione S-transferase alpha 4	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
GSTA4	DB00515	glutathione S-transferase alpha 4	approved	Cisplatin	N[Pt](N)(Cl)Cl
GSTA4	DB01248	glutathione S-transferase alpha 4	approved; investigational	Docetaxel	CC(=O)O[C@@]12CO[C@@H]1C[C@H](O)[C@]1(C)[C@@H]2[C@H](OC(=O)C2=CC=CC=C2)[C@]2(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C3=CC=CC=C3)C(C)=C([C@@H](O)C1=O)C2(C)C
GSTA5	DB00143	glutathione S-transferase alpha 5	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
GSTA5	DB00515	glutathione S-transferase alpha 5	approved	Cisplatin	N[Pt](N)(Cl)Cl
GSTK1	DB00143	glutathione S-transferase kappa 1	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
GSTK1	DB04700	glutathione S-transferase kappa 1	experimental	GLUTATHIONE SULFINATE	N[C@@H](CCC(=O)N[C@@H](C[S@](O)=O)C(=O)NCC(O)=O)C(O)=O
GSTM1	DB00143	glutathione S-transferase mu 1	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
GSTM1	DB01834	glutathione S-transferase mu 1	experimental	(9r,10r)-9-(S-Glutathionyl)-10-Hydroxy-9,10-Dihydrophenanthrene	N[C@@H](CCC(=O)N[C@H](CS[C@H]1[C@H](O)C2=CC=CC=C2C2=CC=CC=C12)C(=O)NCC(O)=O)C(O)=O
GSTM1	DB02165	glutathione S-transferase mu 1	experimental	Zinc Trihydroxide	O[Zn-](O)O
GSTM1	DB02458	glutathione S-transferase mu 1	experimental	Glutathione S-(2,4 Dinitrobenzene)	N[C@@H](CCC(=O)N[C@H](CSC1=CC=C(C=C1[N+]([O-])=O)[N+]([O-])=O)C(=O)NCC(O)=O)C(O)=O
GSTM1	DB03314	glutathione S-transferase mu 1	experimental	Fluorotryptophane	N[C@@H](CC1=CNC2=C1C=C(F)C=C2)C(O)=O
GSTM1	DB04187	glutathione S-transferase mu 1	experimental	(9s,10s)-9-(S-Glutathionyl)-10-Hydroxy-9,10-Dihydrophenanthrene	N[C@@H](CCC(=O)N[C@H](CS[C@H]1[C@H](O)C2=CC=CC=C2C2=CC=CC=C12)C(=O)NCC(O)=O)C(O)=O
GSTM1	DB01234	glutathione S-transferase mu 1	approved; investigational	Dexamethasone	C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
GSTM1	DB04572	glutathione S-transferase mu 1	approved	Thiotepa	S=P(N1CC1)(N1CC1)N1CC1
GSTM1	DB01248	glutathione S-transferase mu 1	approved; investigational	Docetaxel	CC(=O)O[C@@]12CO[C@@H]1C[C@H](O)[C@]1(C)[C@@H]2[C@H](OC(=O)C2=CC=CC=C2)[C@]2(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C3=CC=CC=C3)C(C)=C([C@@H](O)C1=O)C2(C)C
GSTM1	DB00412	glutathione S-transferase mu 1	approved; investigational	Rosiglitazone	CN(CCOC1=CC=C(CC2SC(=O)NC2=O)C=C1)C1=CC=CC=N1
GSTM1	DB00993	glutathione S-transferase mu 1	approved	Azathioprine	CN1C=NC(=C1SC1=NC=NC2=C1NC=N2)[N+]([O-])=O
GSTM1	DB01181	glutathione S-transferase mu 1	approved	Ifosfamide	ClCCNP1(=O)OCCCN1CCCl
GSTM1	DB00526	glutathione S-transferase mu 1	approved; investigational	Oxaliplatin	O=C1O[Pt]2(N[C@@H]3CCCC[C@H]3N2)OC1=O
GSTM1	DB00445	glutathione S-transferase mu 1	approved	Epirubicin	COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3O[C@H]3C[C@H](N)[C@@H](O)[C@H](C)O3)C(=O)CO)C(O)=C1C2=O
GSTM1	DB00951	glutathione S-transferase mu 1	approved	Isoniazid	NNC(=O)C1=CC=NC=C1
GSTM1	DB00515	glutathione S-transferase mu 1	approved	Cisplatin	N[Pt](N)(Cl)Cl
GSTM1	DB00531	glutathione S-transferase mu 1	approved; investigational	Cyclophosphamide	ClCCN(CCCl)P1(=O)NCCCO1
GSTM1	DB00544	glutathione S-transferase mu 1	approved	Fluorouracil	FC1=CNC(=O)NC1=O
GSTM1	DB00291	glutathione S-transferase mu 1	approved	Chlorambucil	OC(=O)CCCC1=CC=C(C=C1)N(CCCl)CCCl
GSTM1	DB00997	glutathione S-transferase mu 1	approved; investigational	Doxorubicin	COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3O[C@H]3C[C@H](N)[C@H](O)[C@H](C)O3)C(=O)CO)C(O)=C1C2=O
GSTM1	DB01204	glutathione S-transferase mu 1	approved; investigational	Mitoxantrone	OCCNCCNC1=C2C(=O)C3=C(O)C=CC(O)=C3C(=O)C2=C(NCCNCCO)C=C1
GSTM1	DB00444	glutathione S-transferase mu 1	approved	Teniposide	COC1=CC(=CC(OC)=C1O)[C@H]1[C@@H]2[C@H](COC2=O)[C@H](O[C@@H]2O[C@@H]3COC(O[C@H]3[C@H](O)[C@H]2O)C2=CC=CS2)C2=CC3=C(OCO3)C=C12
GSTM1	DB01008	glutathione S-transferase mu 1	approved; investigational	Busulfan	CS(=O)(=O)OCCCCOS(C)(=O)=O
GSTM1	DB01042	glutathione S-transferase mu 1	approved	Melphalan	NC(CC1=CC=C(C=C1)N(CCCl)CCCl)C(O)=O
GSTM1	DB00564	glutathione S-transferase mu 1	approved; investigational	Carbamazepine	NC(=O)N1C2=CC=CC=C2C=CC2=CC=CC=C12
GSTM1	DB00987	glutathione S-transferase mu 1	approved; investigational	Cytarabine	NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O
GSTM1	DB00694	glutathione S-transferase mu 1	approved	Daunorubicin	COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3O[C@H]3C[C@H](N)[C@H](O)[C@H](C)O3)C(C)=O)C(O)=C1C2=O
GSTM1	DB00773	glutathione S-transferase mu 1	approved	Etoposide	COC1=CC(=CC(OC)=C1O)[C@H]1[C@@H]2[C@H](COC2=O)[C@H](O[C@@H]2O[C@@H]3CO[C@@H](C)O[C@H]3[C@H](O)[C@H]2O)C2=CC3=C(OCO3)C=C12
GSTM1	DB00650	glutathione S-transferase mu 1	approved	Leucovorin	NC1=NC(=O)C2=C(NCC(CNC3=CC=C(C=C3)C(=O)N[C@H](CCC(O)=O)C(O)=O)N2C=O)N1
GSTM1	DB01033	glutathione S-transferase mu 1	approved	Mercaptopurine	S=C1N=CNC2=C1NC=N2
GSTM1	DB00563	glutathione S-transferase mu 1	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
GSTM1	DB00635	glutathione S-transferase mu 1	approved	Prednisone	C[C@]12CC(=O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
GSTM1	DB00541	glutathione S-transferase mu 1	approved; investigational	Vincristine	CC[C@]1(O)C[C@H]2CN(C1)CCC1=C(NC3=CC=CC=C13)[C@@](C2)(C(=O)OC)C1=C(OC)C=C2N(C=O)[C@@H]3[C@]4(CCN5CC=C[C@](CC)([C@@H]45)[C@@H](OC(C)=O)[C@]3(O)C(=O)OC)C2=C1
GSTM1	DB01143	glutathione S-transferase mu 1	approved; investigational	Amifostine	NCCCNCCSP(O)(O)=O
GSTM1	DB00958	glutathione S-transferase mu 1	approved	Carboplatin	N.N.O=C1O[Pt]OC(=O)C11CCC1
GSTM1	DB01229	glutathione S-transferase mu 1	approved	Paclitaxel	CC(=O)O[C@@H]1C2=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)C3=CC=CC=C3)[C@@H]3[C@@]4(CO[C@@H]4C[C@H](O)[C@@]3(C)C1=O)OC(C)=O)C2(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)C1=CC=CC=C1)C1=CC=CC=C1
GSTM1	DB01101	glutathione S-transferase mu 1	approved; investigational	Capecitabine	CCCCCOC(=O)NC1=NC(=O)N(C=C1F)[C@@H]1O[C@H](C)[C@@H](O)[C@H]1O
GSTM1	DB00762	glutathione S-transferase mu 1	approved; investigational	Irinotecan	CCC1=C2CN3C(=CC4=C(COC(=O)[C@]4(O)CC)C3=O)C2=NC2=C1C=C(OC(=O)N1CCC(CC1)N1CCCCC1)C=C2
GSTM1	DB00382	glutathione S-transferase mu 1	approved	Tacrine	NC1=C2CCCCC2=NC2=CC=CC=C12
GSTM1	DB01060	glutathione S-transferase mu 1	approved	Amoxicillin	CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)C3=CC=C(O)C=C3)C(=O)N2[C@H]1C(O)=O
GSTM1	DB00766	glutathione S-transferase mu 1	approved	Clavulanate	OC\C=C1/O[C@@H]2CC(=O)N2[C@H]1C(O)=O
GSTM1	DB00197	glutathione S-transferase mu 1	withdrawn	Troglitazone	CC1=C(C)C2=C(CCC(C)(COC3=CC=C(CC4SC(=O)NC4=O)C=C3)O2)C(C)=C1O
GSTM2	DB00143	glutathione S-transferase mu 2 (muscle)	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
GSTM2	DB02458	glutathione S-transferase mu 2 (muscle)	experimental	Glutathione S-(2,4 Dinitrobenzene)	N[C@@H](CCC(=O)N[C@H](CSC1=CC=C(C=C1[N+]([O-])=O)[N+]([O-])=O)C(=O)NCC(O)=O)C(O)=O
GSTM2	DB03310	glutathione S-transferase mu 2 (muscle)	experimental	Oxidized Glutathione Disulfide	N[C@H](CCC(=O)N[C@H](CSSC[C@@H](NC(=O)CC[C@@H](N)C(O)=O)C(=O)NCC(O)=O)C(=O)NCC(O)=O)C(O)=O
GSTM2	DB04701	glutathione S-transferase mu 2 (muscle)	experimental	S-METHYL-GLUTATHIONE	CSC[C@H](NC(=O)CC[C@H](N)C(O)=O)C(=O)NCC(O)=O
GSTM2	DB00515	glutathione S-transferase mu 2 (muscle)	approved	Cisplatin	N[Pt](N)(Cl)Cl
GSTM2	DB01008	glutathione S-transferase mu 2 (muscle)	approved; investigational	Busulfan	CS(=O)(=O)OCCCCOS(C)(=O)=O
GSTM2	DB00988	glutathione S-transferase mu 2 (muscle)	approved	Dopamine	NCCC1=CC(O)=C(O)C=C1
GSTM2	DB00668	glutathione S-transferase mu 2 (muscle)	approved	Epinephrine	CNC[C@H](O)C1=CC(O)=C(O)C=C1
GSTM3	DB00143	glutathione S-transferase mu 3 (brain)	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
GSTM3	DB00958	glutathione S-transferase mu 3 (brain)	approved	Carboplatin	N.N.O=C1O[Pt]OC(=O)C11CCC1
GSTM3	DB00997	glutathione S-transferase mu 3 (brain)	approved; investigational	Doxorubicin	COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3O[C@H]3C[C@H](N)[C@H](O)[C@H](C)O3)C(=O)CO)C(O)=C1C2=O
GSTM3	DB01181	glutathione S-transferase mu 3 (brain)	approved	Ifosfamide	ClCCNP1(=O)OCCCN1CCCl
GSTM3	DB00515	glutathione S-transferase mu 3 (brain)	approved	Cisplatin	N[Pt](N)(Cl)Cl
GSTM3	DB00531	glutathione S-transferase mu 3 (brain)	approved; investigational	Cyclophosphamide	ClCCN(CCCl)P1(=O)NCCCO1
GSTM4	DB00143	glutathione S-transferase mu 4	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
GSTM4	DB03003	glutathione S-transferase mu 4	experimental	Glutathione Sulfonic Acid	N[C@@H](CCC(=O)N[C@H](CS(O)(=O)=O)C(=O)NCC(O)=O)C(O)=O
GSTM4	DB03032	glutathione S-transferase mu 4	experimental	S-Octylglutathione	CCCCCCCCSC[C@@H](NC(=O)CC[C@H](N)C(O)=O)C(=O)NCC(O)=O
GSTM4	DB03597	glutathione S-transferase mu 4	experimental	Gamma-Glutamyl[S-(2-Iodobenzyl)Cysteinyl]Glycine	N[C@@H](CCC(=O)N[C@H](CSCC1=CC=CC=C1I)C(=O)NCC(O)=O)C(O)=O
GSTM4	DB03706	glutathione S-transferase mu 4	experimental	1-Hydroxy-2-S-Glutathionyl-3-Para-Nitrophenoxy-Propane	N[C@@H](CCC(=O)N[C@H](CS[C@H](CO)COC1=CC=C(C=C1)[N+]([O-])=O)C(=O)NCC(O)=O)C(O)=O
GSTM4	DB04132	glutathione S-transferase mu 4	experimental	S-Hexylglutathione	CCCCCCSC[C@@H](NC(=O)CC[C@H]([NH3+])C(O)=O)C(=O)NCC(O)=O
GSTM4	DB00515	glutathione S-transferase mu 4	approved	Cisplatin	N[Pt](N)(Cl)Cl
GSTM5	DB00143	glutathione S-transferase mu 5	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
GSTM5	DB00515	glutathione S-transferase mu 5	approved	Cisplatin	N[Pt](N)(Cl)Cl
GSTM5	DB01248	glutathione S-transferase mu 5	approved; investigational	Docetaxel	CC(=O)O[C@@]12CO[C@@H]1C[C@H](O)[C@]1(C)[C@@H]2[C@H](OC(=O)C2=CC=CC=C2)[C@]2(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C3=CC=CC=C3)C(C)=C([C@@H](O)C1=O)C2(C)C
GSTO1	DB00143	glutathione S-transferase omega 1	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
GSTO1	DB00515	glutathione S-transferase omega 1	approved	Cisplatin	N[Pt](N)(Cl)Cl
GSTO1	DB01169	glutathione S-transferase omega 1	approved; investigational	Arsenic trioxide	O1[As]2O[As]1O2
GSTO2	DB00143	glutathione S-transferase omega 2	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
GSTO2	DB00515	glutathione S-transferase omega 2	approved	Cisplatin	N[Pt](N)(Cl)Cl
GSTO2	DB01169	glutathione S-transferase omega 2	approved; investigational	Arsenic trioxide	O1[As]2O[As]1O2
GSTP1	DB00143	glutathione S-transferase pi 1	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
GSTP1	DB01242	glutathione S-transferase pi 1	approved	Clomipramine	CN(C)CCCN1C2=CC=CC=C2CCC2=C1C=C(Cl)C=C2
GSTP1	DB01834	glutathione S-transferase pi 1	experimental	(9r,10r)-9-(S-Glutathionyl)-10-Hydroxy-9,10-Dihydrophenanthrene	N[C@@H](CCC(=O)N[C@H](CS[C@H]1[C@H](O)C2=CC=CC=C2C2=CC=CC=C12)C(=O)NCC(O)=O)C(O)=O
GSTP1	DB01915	glutathione S-transferase pi 1	experimental	S-Hydroxycysteine	N[C@@H](CSO)C(O)=O
GSTP1	DB02633	glutathione S-transferase pi 1	experimental	Cibacron Blue	NC1=C(C=C(NC2=CC=C(NC3=NC(Cl)=NC(NC4=CC=CC=C4S(O)(=O)=O)=N3)C(=C2)S(O)(=O)=O)C2=C1C(=O)C1=CC=CC=C1C2=O)S(O)(=O)=O
GSTP1	DB03003	glutathione S-transferase pi 1	experimental	Glutathione Sulfonic Acid	N[C@@H](CCC(=O)N[C@H](CS(O)(=O)=O)C(=O)NCC(O)=O)C(O)=O
GSTP1	DB03686	glutathione S-transferase pi 1	experimental	S-(P-Nitrobenzyl)Glutathione	N[C@@H](CCC(=O)N[C@H](CSCC1=CC=C(C=C1)[N+]([O-])=O)C(=O)NCC(O)=O)C(O)=O
GSTP1	DB03814	glutathione S-transferase pi 1	experimental	2-(N-Morpholino)-Ethanesulfonic Acid	[O-]S(=O)(=O)CC[NH+]1CCOCC1
GSTP1	DB04077	glutathione S-transferase pi 1	experimental	Glycerol	OCC(O)CO
GSTP1	DB04132	glutathione S-transferase pi 1	experimental	S-Hexylglutathione	CCCCCCSC[C@@H](NC(=O)CC[C@H]([NH3+])C(O)=O)C(=O)NCC(O)=O
GSTP1	DB04339	glutathione S-transferase pi 1	experimental	Carboxymethylenecysteine	N[C@@H](CSCC(O)=O)C(O)=O
GSTP1	DB07849	glutathione S-transferase pi 1	experimental	S-NONYL-CYSTEINE	CCCCCCCCCSC[C@H](N)C(O)=O
GSTP1	DB08370	glutathione S-transferase pi 1	experimental	S-(4-BROMOBENZYL)CYSTEINE	N[C@@H](CSCC1=CC=C(Br)C=C1)C(O)=O
GSTP1	DB00443	glutathione S-transferase pi 1	approved	Betamethasone	C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
GSTP1	DB01234	glutathione S-transferase pi 1	approved; investigational	Dexamethasone	C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
GSTP1	DB00997	glutathione S-transferase pi 1	approved; investigational	Doxorubicin	COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3O[C@H]3C[C@H](N)[C@H](O)[C@H](C)O3)C(=O)CO)C(O)=C1C2=O
GSTP1	DB01236	glutathione S-transferase pi 1	approved	Sevoflurane	FCOC(C(F)(F)F)C(F)(F)F
GSTP1	DB04572	glutathione S-transferase pi 1	approved	Thiotepa	S=P(N1CC1)(N1CC1)N1CC1
GSTP1	DB01229	glutathione S-transferase pi 1	approved	Paclitaxel	CC(=O)O[C@@H]1C2=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)C3=CC=CC=C3)[C@@H]3[C@@]4(CO[C@@H]4C[C@H](O)[C@@]3(C)C1=O)OC(C)=O)C2(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)C1=CC=CC=C1)C1=CC=CC=C1
GSTP1	DB00928	glutathione S-transferase pi 1	approved; investigational	Azacitidine	NC1=NC(=O)N(C=N1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
GSTP1	DB00313	glutathione S-transferase pi 1	approved; investigational	Valproic Acid	CCCC(CCC)C(O)=O
GSTP1	DB00445	glutathione S-transferase pi 1	approved	Epirubicin	COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3O[C@H]3C[C@H](N)[C@@H](O)[C@H](C)O3)C(=O)CO)C(O)=C1C2=O
GSTP1	DB00205	glutathione S-transferase pi 1	approved	Pyrimethamine	CCC1=C(C(N)=NC(N)=N1)C1=CC=C(Cl)C=C1
GSTP1	DB01248	glutathione S-transferase pi 1	approved; investigational	Docetaxel	CC(=O)O[C@@]12CO[C@@H]1C[C@H](O)[C@]1(C)[C@@H]2[C@H](OC(=O)C2=CC=CC=C2)[C@]2(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C3=CC=CC=C3)C(C)=C([C@@H](O)C1=O)C2(C)C
GSTP1	DB00544	glutathione S-transferase pi 1	approved	Fluorouracil	FC1=CNC(=O)NC1=O
GSTP1	DB00291	glutathione S-transferase pi 1	approved	Chlorambucil	OC(=O)CCCC1=CC=C(C=C1)N(CCCl)CCCl
GSTP1	DB01204	glutathione S-transferase pi 1	approved; investigational	Mitoxantrone	OCCNCCNC1=C2C(=O)C3=C(O)C=CC(O)=C3C(=O)C2=C(NCCNCCO)C=C1
GSTP1	DB00515	glutathione S-transferase pi 1	approved	Cisplatin	N[Pt](N)(Cl)Cl
GSTP1	DB00526	glutathione S-transferase pi 1	approved; investigational	Oxaliplatin	O=C1O[Pt]2(N[C@@H]3CCCC[C@H]3N2)OC1=O
GSTP1	DB00531	glutathione S-transferase pi 1	approved; investigational	Cyclophosphamide	ClCCN(CCCl)P1(=O)NCCCO1
GSTP1	DB00958	glutathione S-transferase pi 1	approved	Carboplatin	N.N.O=C1O[Pt]OC(=O)C11CCC1
GSTP1	DB00762	glutathione S-transferase pi 1	approved; investigational	Irinotecan	CCC1=C2CN3C(=CC4=C(COC(=O)[C@]4(O)CC)C3=O)C2=NC2=C1C=C(OC(=O)N1CCC(CC1)N1CCCCC1)C=C2
GSTP1	DB00987	glutathione S-transferase pi 1	approved; investigational	Cytarabine	NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O
GSTP1	DB00694	glutathione S-transferase pi 1	approved	Daunorubicin	COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3O[C@H]3C[C@H](N)[C@H](O)[C@H](C)O3)C(C)=O)C(O)=C1C2=O
GSTP1	DB00773	glutathione S-transferase pi 1	approved	Etoposide	COC1=CC(=CC(OC)=C1O)[C@H]1[C@@H]2[C@H](COC2=O)[C@H](O[C@@H]2O[C@@H]3CO[C@@H](C)O[C@H]3[C@H](O)[C@H]2O)C2=CC3=C(OCO3)C=C12
GSTP1	DB00650	glutathione S-transferase pi 1	approved	Leucovorin	NC1=NC(=O)C2=C(NCC(CNC3=CC=C(C=C3)C(=O)N[C@H](CCC(O)=O)C(O)=O)N2C=O)N1
GSTP1	DB01033	glutathione S-transferase pi 1	approved	Mercaptopurine	S=C1N=CNC2=C1NC=N2
GSTP1	DB00563	glutathione S-transferase pi 1	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
GSTP1	DB00635	glutathione S-transferase pi 1	approved	Prednisone	C[C@]12CC(=O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
GSTP1	DB00541	glutathione S-transferase pi 1	approved; investigational	Vincristine	CC[C@]1(O)C[C@H]2CN(C1)CCC1=C(NC3=CC=CC=C13)[C@@](C2)(C(=O)OC)C1=C(OC)C=C2N(C=O)[C@@H]3[C@]4(CCN5CC=C[C@](CC)([C@@H]45)[C@@H](OC(C)=O)[C@]3(O)C(=O)OC)C2=C1
GSTP1	DB01042	glutathione S-transferase pi 1	approved	Melphalan	NC(CC1=CC=C(C=C1)N(CCCl)CCCl)C(O)=O
GSTP1	DB01008	glutathione S-transferase pi 1	approved; investigational	Busulfan	CS(=O)(=O)OCCCCOS(C)(=O)=O
GSTP1	DB01101	glutathione S-transferase pi 1	approved; investigational	Capecitabine	CCCCCOC(=O)NC1=NC(=O)N(C=C1F)[C@@H]1O[C@H](C)[C@@H](O)[C@H]1O
GSTT1	DB00143	glutathione S-transferase theta 1	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
GSTT1	DB01234	glutathione S-transferase theta 1	approved; investigational	Dexamethasone	C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
GSTT1	DB00650	glutathione S-transferase theta 1	approved	Leucovorin	NC1=NC(=O)C2=C(NCC(CNC3=CC=C(C=C3)C(=O)N[C@H](CCC(O)=O)C(O)=O)N2C=O)N1
GSTT1	DB00997	glutathione S-transferase theta 1	approved; investigational	Doxorubicin	COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3O[C@H]3C[C@H](N)[C@H](O)[C@H](C)O3)C(=O)CO)C(O)=C1C2=O
GSTT1	DB04572	glutathione S-transferase theta 1	approved	Thiotepa	S=P(N1CC1)(N1CC1)N1CC1
GSTT1	DB00412	glutathione S-transferase theta 1	approved; investigational	Rosiglitazone	CN(CCOC1=CC=C(CC2SC(=O)NC2=O)C=C1)C1=CC=CC=N1
GSTT1	DB00958	glutathione S-transferase theta 1	approved	Carboplatin	N.N.O=C1O[Pt]OC(=O)C11CCC1
GSTT1	DB01181	glutathione S-transferase theta 1	approved	Ifosfamide	ClCCNP1(=O)OCCCN1CCCl
GSTT1	DB00526	glutathione S-transferase theta 1	approved; investigational	Oxaliplatin	O=C1O[Pt]2(N[C@@H]3CCCC[C@H]3N2)OC1=O
GSTT1	DB00445	glutathione S-transferase theta 1	approved	Epirubicin	COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3O[C@H]3C[C@H](N)[C@@H](O)[C@H](C)O3)C(=O)CO)C(O)=C1C2=O
GSTT1	DB00515	glutathione S-transferase theta 1	approved	Cisplatin	N[Pt](N)(Cl)Cl
GSTT1	DB00531	glutathione S-transferase theta 1	approved; investigational	Cyclophosphamide	ClCCN(CCCl)P1(=O)NCCCO1
GSTT1	DB00544	glutathione S-transferase theta 1	approved	Fluorouracil	FC1=CNC(=O)NC1=O
GSTT1	DB00444	glutathione S-transferase theta 1	approved	Teniposide	COC1=CC(=CC(OC)=C1O)[C@H]1[C@@H]2[C@H](COC2=O)[C@H](O[C@@H]2O[C@@H]3COC(O[C@H]3[C@H](O)[C@H]2O)C2=CC=CS2)C2=CC3=C(OCO3)C=C12
GSTT1	DB01042	glutathione S-transferase theta 1	approved	Melphalan	NC(CC1=CC=C(C=C1)N(CCCl)CCCl)C(O)=O
GSTT1	DB00564	glutathione S-transferase theta 1	approved; investigational	Carbamazepine	NC(=O)N1C2=CC=CC=C2C=CC2=CC=CC=C12
GSTT1	DB00987	glutathione S-transferase theta 1	approved; investigational	Cytarabine	NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O
GSTT1	DB00694	glutathione S-transferase theta 1	approved	Daunorubicin	COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3O[C@H]3C[C@H](N)[C@H](O)[C@H](C)O3)C(C)=O)C(O)=C1C2=O
GSTT1	DB00773	glutathione S-transferase theta 1	approved	Etoposide	COC1=CC(=CC(OC)=C1O)[C@H]1[C@@H]2[C@H](COC2=O)[C@H](O[C@@H]2O[C@@H]3CO[C@@H](C)O[C@H]3[C@H](O)[C@H]2O)C2=CC3=C(OCO3)C=C12
GSTT1	DB01033	glutathione S-transferase theta 1	approved	Mercaptopurine	S=C1N=CNC2=C1NC=N2
GSTT1	DB00563	glutathione S-transferase theta 1	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
GSTT1	DB00635	glutathione S-transferase theta 1	approved	Prednisone	C[C@]12CC(=O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
GSTT1	DB00541	glutathione S-transferase theta 1	approved; investigational	Vincristine	CC[C@]1(O)C[C@H]2CN(C1)CCC1=C(NC3=CC=CC=C13)[C@@](C2)(C(=O)OC)C1=C(OC)C=C2N(C=O)[C@@H]3[C@]4(CCN5CC=C[C@](CC)([C@@H]45)[C@@H](OC(C)=O)[C@]3(O)C(=O)OC)C2=C1
GSTT1	DB01008	glutathione S-transferase theta 1	approved; investigational	Busulfan	CS(=O)(=O)OCCCCOS(C)(=O)=O
GSTT1	DB01101	glutathione S-transferase theta 1	approved; investigational	Capecitabine	CCCCCOC(=O)NC1=NC(=O)N(C=C1F)[C@@H]1O[C@H](C)[C@@H](O)[C@H]1O
GSTT1	DB00762	glutathione S-transferase theta 1	approved; investigational	Irinotecan	CCC1=C2CN3C(=CC4=C(COC(=O)[C@]4(O)CC)C3=O)C2=NC2=C1C=C(OC(=O)N1CCC(CC1)N1CCCCC1)C=C2
GSTT1	DB00382	glutathione S-transferase theta 1	approved	Tacrine	NC1=C2CCCCC2=NC2=CC=CC=C12
GSTT1	DB01060	glutathione S-transferase theta 1	approved	Amoxicillin	CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)C3=CC=C(O)C=C3)C(=O)N2[C@H]1C(O)=O
GSTT1	DB00766	glutathione S-transferase theta 1	approved	Clavulanate	OC\C=C1/O[C@@H]2CC(=O)N2[C@H]1C(O)=O
GSTT1	DB00951	glutathione S-transferase theta 1	approved	Isoniazid	NNC(=O)C1=CC=NC=C1
GSTT1	DB00197	glutathione S-transferase theta 1	withdrawn	Troglitazone	CC1=C(C)C2=C(CCC(C)(COC3=CC=C(CC4SC(=O)NC4=O)C=C3)O2)C(C)=C1O
GSTT2	DB00515	glutathione S-transferase theta 2	approved	Cisplatin	N[Pt](N)(Cl)Cl
GSTT2	DB01248	glutathione S-transferase theta 2	approved; investigational	Docetaxel	CC(=O)O[C@@]12CO[C@@H]1C[C@H](O)[C@]1(C)[C@@H]2[C@H](OC(=O)C2=CC=CC=C2)[C@]2(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C3=CC=CC=C3)C(C)=C([C@@H](O)C1=O)C2(C)C
GSTZ1	DB00143	glutathione S-transferase zeta 1	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
GSTZ1	DB04447	glutathione S-transferase zeta 1	experimental	1,4-Dithiothreitol	O[C@H](CS)[C@H](O)CS
GSTZ1	DB00515	glutathione S-transferase zeta 1	approved	Cisplatin	N[Pt](N)(Cl)Cl
GSTZ1	DB00120	glutathione S-transferase zeta 1	approved; nutraceutical	L-Phenylalanine	N[C@@H](CC1=CC=CC=C1)C(O)=O
GSTZ1	DB00135	glutathione S-transferase zeta 1	approved; nutraceutical	L-Tyrosine	N[C@@H](CC1=CC=C(O)C=C1)C(O)=O
GSTZ1	DB00360	glutathione S-transferase zeta 1	approved; investigational	Tetrahydrobiopterin	CC(O)C(O)C1CNC2=C(N1)C(=O)N=C(N)N2
GUCY1B3	DB00171	guanylate cyclase 1, soluble, beta 3	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
GUCY1B3	DB00125	guanylate cyclase 1, soluble, beta 3	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
GUCY1B3	DB00155	guanylate cyclase 1, soluble, beta 3	approved; nutraceutical	L-Citrulline	N[C@@H](CCCNC(N)=O)C(O)=O
GUCY1B3	DB00435	guanylate cyclase 1, soluble, beta 3	approved	Nitric Oxide	[N]=O
GUCY2D	DB00131	guanylate cyclase 2D, membrane (retina-specific)	approved; nutraceutical	Adenosine monophosphate	NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
GUCY2D	DB00125	guanylate cyclase 2D, membrane (retina-specific)	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
GUCY2D	DB00155	guanylate cyclase 2D, membrane (retina-specific)	approved; nutraceutical	L-Citrulline	N[C@@H](CCCNC(N)=O)C(O)=O
GUCY2D	DB00435	guanylate cyclase 2D, membrane (retina-specific)	approved	Nitric Oxide	[N]=O
GUK1	DB01972	guanylate kinase 1	experimental	Guanosine-5'-Monophosphate	NC1=NC2=C(N=CN2[C@@H]2O[C@@H](COP(O)(O)=O)[C@H](O)[C@H]2O)C(=O)N1
GUK1	DB03431	guanylate kinase 1	experimental	Adenosine-5'-Diphosphate	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](CO[P@](O)(=O)OP(O)(O)=O)[C@H](O)[C@H]1O
GUK1	DB01942	guanylate kinase 1	experimental	Formic Acid	OC=O
GUK1	DB00130	guanylate kinase 1	approved; nutraceutical; investigational	L-Glutamine	N[C@@H](CCC(N)=O)C(O)=O
GUSB	DB02944	glucuronidase, beta	experimental	Alpha-D-Mannose	OC[C@@H]1O[C@H](O)[C@@H](O)[C@H](O)[C@H]1O
GYS2	DB01033	glycogen synthase 2 (liver)	approved	Mercaptopurine	S=C1N=CNC2=C1NC=N2
HAAO	DB00130	3-hydroxyanthranilate 3,4-dioxygenase	approved; nutraceutical; investigational	L-Glutamine	N[C@@H](CCC(N)=O)C(O)=O
HAAO	DB00160	3-hydroxyanthranilate 3,4-dioxygenase	approved; nutraceutical	L-Alanine	C[C@H](N)C(O)=O
HAAO	DB00150	3-hydroxyanthranilate 3,4-dioxygenase	approved; nutraceutical	L-Tryptophan	N[C@@H](CC1=CNC2=CC=CC=C12)C(O)=O
HADH	DB00157	hydroxyacyl-CoA dehydrogenase	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
HADH	DB01907	hydroxyacyl-CoA dehydrogenase	experimental	Nicotinamide-Adenine-Dinucleotide	NC(=O)C1=CC=C[N+](=C1)[C@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@@H]1O
HADH	DB03059	hydroxyacyl-CoA dehydrogenase	experimental	Acetoacetyl-Coenzyme A	CC(=O)CC(=O)SCCNC(=O)CCNC(=O)[C@@H](O)C(C)(C)CO[P@](O)(=O)O[P@@](O)(=O)OC[C@@H]1O[C@H]([C@H](O)[C@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N
HADH	DB03612	hydroxyacyl-CoA dehydrogenase	experimental	3-Hydroxybutyryl-Coenzyme A	C[C@@H](O)CC(=O)SCCNC(=O)CCNC(=O)[C@@H](O)C(C)(C)CO[P@](O)(=O)O[P@@](O)(=O)OC[C@@H]1O[C@H]([C@H](O)[C@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N
HADH	DB00123	hydroxyacyl-CoA dehydrogenase	approved; nutraceutical	L-Lysine	NCCCC[C@H](N)C(O)=O
HADHA	DB00157	hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
HAGH	DB00143	hydroxyacylglutathione hydrolase	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
HAGH	DB03889	hydroxyacylglutathione hydrolase	experimental	S-(N-Hydroxy-N-Bromophenylcarbamoyl)Glutathione	N[C@@H](CCC(=O)N[C@H](CS[C@H](O)N(O)C1=CC=C(Br)C=C1)C(=O)NCC(O)=O)C(O)=O
HAL	DB00117	histidine ammonia-lyase	approved; nutraceutical	L-Histidine	N[C@@H](CC1=CN=CN1)C(O)=O
HAL	DB06946	histidine ammonia-lyase	experimental	(2S,3S)-3-(4-fluorophenyl)-2,3-dihydroxypropanoic acid	O[C@@H]([C@@H](O)C1=CC=C(F)C=C1)C(O)=O
HAL	DB01880	histidine ammonia-lyase	experimental	3,4-Dihydroxycinnamic Acid	OC(=O)\C=C\C1=CC(O)=C(O)C=C1
HAL	DB04066	histidine ammonia-lyase	experimental	Para-Coumaric Acid	OC(=O)\C=C\C1=CC=C(O)C=C1
HAO1	DB02164	hydroxyacid oxidase (glycolate oxidase) 1	experimental	N-Sulfo-Flavin Mononucleotide	CC1=CC2=C(C=C1C)[N+](=C1C(=O)NC(=O)N=C1N2C[C@@H](O)[C@@H](O)[C@H](O)COP(O)(O)=O)S([O-])(=O)=O
HAO1	DB02279	hydroxyacid oxidase (glycolate oxidase) 1	experimental	Benzoylformic Acid	OC(=O)C(=O)C1=CC=CC=C1
HAO1	DB03014	hydroxyacid oxidase (glycolate oxidase) 1	experimental	Heme	CC1=C(CCC(O)=O)C2=CC3=[N+]4C(=CC5=C(C=C)C(C)=C6C=C7C(C=C)=C(C)C8=[N+]7[Fe@]4(N2C1=C8)N56)C(C)=C3CCC(O)=O
HAO1	DB03064	hydroxyacid oxidase (glycolate oxidase) 1	experimental	3-Decyl-2,5-Dioxo-4-Hydroxy-3-Pyrroline	CCCCCCCCCCC1=C(O)C(=O)NC1=O
HAO1	DB03247	hydroxyacid oxidase (glycolate oxidase) 1	experimental	Riboflavin Monophosphate	CC1=CC2=C(C=C1C)N(C[C@@H](O)[C@@H](O)[C@H](O)COP(O)(O)=O)C1=NC(=O)NC(=O)C1=N2
HAO1	DB03884	hydroxyacid oxidase (glycolate oxidase) 1	experimental	3-Phenylpyruvic Acid	OC(=O)C(=O)CC1=CC=CC=C1
HAO1	DB04374	hydroxyacid oxidase (glycolate oxidase) 1	experimental	4-Carboxy-5-(1-Pentyl)Hexylsulfanyl-1,2,3-Triazole	CCCCCC(CCCCC)SC1=C(N=NN1)C(O)=O
HAO1	DB06979	hydroxyacid oxidase (glycolate oxidase) 1	experimental	5-(dodecylthio)-1H-1,2,3-triazole-4-carboxylic acid	CCCCCCCCCCCCSC1=C(N=NN1)C(O)=O
HAO1	DB07060	hydroxyacid oxidase (glycolate oxidase) 1	experimental	3-(INDOL-3-YL) LACTATE	O[C@@H](CC1=CNC2=C1C=CC=C2)C(O)=O
HAO1	DB07907	hydroxyacid oxidase (glycolate oxidase) 1	experimental	(2S)-2-HYDROXYOCTANOIC ACID	CCCCCC[C@H](O)C(O)=O
HAO1	DB00145	hydroxyacid oxidase (glycolate oxidase) 1	approved; nutraceutical	Glycine	NCC(O)=O
HAO1	DB00160	hydroxyacid oxidase (glycolate oxidase) 1	approved; nutraceutical	L-Alanine	C[C@H](N)C(O)=O
HDAC3	DB02546	histone deacetylase 3	approved; investigational	Vorinostat	ONC(=O)CCCCCCC(=O)NC1=CC=CC=C1
HDAC3	DB00313	histone deacetylase 3	approved; investigational	Valproic Acid	CCCC(CCC)C(O)=O
HDC	DB00114	histidine decarboxylase	nutraceutical	Pyridoxal Phosphate	CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O
HDC	DB00117	histidine decarboxylase	approved; nutraceutical	L-Histidine	N[C@@H](CC1=CN=CN1)C(O)=O
HDC	DB00667	histidine decarboxylase	approved	Histamine Phosphate	OP(O)(O)=O.OP(O)(O)=O.NCCC1=CN=CN1
HEMK1	DB01752	HemK methyltransferase family member 1	experimental	S-Adenosyl-L-Homocysteine	N[C@@H](CCSC[C@@H]1O[C@H]([C@H](O)[C@H]1O)N1C=NC2=C1N=CN=C2N)C(O)=O
HEXB	DB02813	hexosaminidase B (beta polypeptide)	experimental	2-Acetamido-2-Deoxy-D-Glucono-1,5-Lactone	CC(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)OC1=O
HEXB	DB03747	hexosaminidase B (beta polypeptide)	experimental	3ar,5r,6s,7r,7ar-5-Hydroxymethyl-2-Methyl-5,6,7,7a-Tetrahydro-3ah-Pyrano[3,2-D]Thiazole-6,7-Diol	CC1=N[C@H]2[C@H](O[C@@H](CO)[C@H](O)[C@H]2O)S1
HEXB	DB03861	hexosaminidase B (beta polypeptide)	experimental	(2r,3r,4s,5r)-2-Acetamido-3,4-Dihydroxy-5-Hydroxymethyl-Piperidinium	CC(=O)N[C@@H]1NC[C@@H](CO)[C@H](O)[C@H]1O
HGD	DB00143	homogentisate 1,2-dioxygenase	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
HGD	DB00120	homogentisate 1,2-dioxygenase	approved; nutraceutical	L-Phenylalanine	N[C@@H](CC1=CC=CC=C1)C(O)=O
HGD	DB00135	homogentisate 1,2-dioxygenase	approved; nutraceutical	L-Tyrosine	N[C@@H](CC1=CC=C(O)C=C1)C(O)=O
HGD	DB00360	homogentisate 1,2-dioxygenase	approved; investigational	Tetrahydrobiopterin	CC(O)C(O)C1CNC2=C(N1)C(=O)N=C(N)N2
HIBADH	DB00157	3-hydroxyisobutyrate dehydrogenase	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
HIBADH	DB00161	3-hydroxyisobutyrate dehydrogenase	approved; nutraceutical	L-Valine	CC(C)[C@H](N)C(O)=O
HIBCH	DB04216	3-hydroxyisobutyryl-CoA hydrolase	experimental	Quercetin	OC1=CC2=C(C(O)=C1)C(=O)C(O)=C(O2)C1=CC=C(O)C(O)=C1
HIBCH	DB00161	3-hydroxyisobutyryl-CoA hydrolase	approved; nutraceutical	L-Valine	CC(C)[C@H](N)C(O)=O
HIF1A	DB08687	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	experimental	N-[(1-CHLORO-4-HYDROXYISOQUINOLIN-3-YL)CARBONYL]GLYCINE	OC(=O)CNC(=O)C1=C(O)C2=CC=CC=C2C(Cl)=N1
HIF1A	DB00171	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
HIF1A	DB00119	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	approved; nutraceutical	Pyruvic acid	CC(=O)C(O)=O
HIF1A	DB00694	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	approved	Daunorubicin	COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3O[C@H]3C[C@H](N)[C@H](O)[C@H](C)O3)C(C)=O)C(O)=C1C2=O
HIF1A	DB00997	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	approved; investigational	Doxorubicin	COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3O[C@H]3C[C@H](N)[C@H](O)[C@H](C)O3)C(=O)CO)C(O)=C1C2=O
HIF1A	DB00773	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	approved	Etoposide	COC1=CC(=CC(OC)=C1O)[C@H]1[C@@H]2[C@H](COC2=O)[C@H](O[C@@H]2O[C@@H]3CO[C@@H](C)O[C@H]3[C@H](O)[C@H]2O)C2=CC3=C(OCO3)C=C12
HIF1A	DB01204	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	approved; investigational	Mitoxantrone	OCCNCCNC1=C2C(=O)C3=C(O)C=CC(O)=C3C(=O)C2=C(NCCNCCO)C=C1
HIF1A	DB00155	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	approved; nutraceutical	L-Citrulline	N[C@@H](CCCNC(N)=O)C(O)=O
HIF1A	DB00125	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
HIF1A	DB00435	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	approved	Nitric Oxide	[N]=O
HK1	DB02007	hexokinase 1	experimental	Alpha-D-Glucose-6-Phosphate	O[C@H]1O[C@@H](COP(O)(O)=O)[C@H](O)[C@@H](O)[C@@H]1O
HK1	DB02379	hexokinase 1	experimental	Beta-D-Glucose	OC[C@@H]1O[C@H](O)[C@@H](O)[C@H](O)[C@H]1O
HK1	DB03431	hexokinase 1	experimental	Adenosine-5'-Diphosphate	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](CO[P@](O)(=O)OP(O)(O)=O)[C@H](O)[C@H]1O
HK1	DB04395	hexokinase 1	experimental	Phosphoaminophosphonic Acid-Adenylate Ester	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](CO[P@](O)(=O)O[P@@](O)(=O)NP(O)(O)=O)[C@H](O)[C@H]1O
HMBS	DB00145	hydroxymethylbilane synthase	approved; nutraceutical	Glycine	NCC(O)=O
HMGCR	DB00157	3-hydroxy-3-methylglutaryl-CoA reductase	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
HMGCR	DB00175	3-hydroxy-3-methylglutaryl-CoA reductase	approved	Pravastatin	CC[C@H](C)C(=O)O[C@H]1C[C@H](O)C=C2C=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC(O)=O)[C@@H]12
HMGCR	DB00227	3-hydroxy-3-methylglutaryl-CoA reductase	approved; investigational	Lovastatin	CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12
HMGCR	DB00439	3-hydroxy-3-methylglutaryl-CoA reductase	withdrawn	Cerivastatin	COCC1=C(C2=CC=C(F)C=C2)C(\C=C\[C@@H](O)C[C@@H](O)CC(O)=O)=C(C(C)C)N=C1C(C)C
HMGCR	DB00641	3-hydroxy-3-methylglutaryl-CoA reductase	approved	Simvastatin	CCC(C)(C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CCC3C[C@@H](O)CC(=O)O3)[C@@H]12
HMGCR	DB01076	3-hydroxy-3-methylglutaryl-CoA reductase	approved	Atorvastatin	CC(C)C1=C(C(=O)NC2=CC=CC=C2)C(=C(N1CC[C@@H](O)C[C@@H](O)CC(O)=O)C1=CC=C(F)C=C1)C1=CC=CC=C1
HMGCR	DB01095	3-hydroxy-3-methylglutaryl-CoA reductase	approved	Fluvastatin	CC(C)N1C(\C=C\[C@H](O)C[C@H](O)CC(O)=O)=C(C2=CC=C(F)C=C2)C2=CC=CC=C12
HMGCR	DB01098	3-hydroxy-3-methylglutaryl-CoA reductase	approved	Rosuvastatin	CC(C)C1=NC(=NC(C2=CC=C(F)C=C2)=C1\C=C\[C@H](O)C[C@@H](O)CC(O)=O)N(C)S(=O)(=O)C
HMGCR	DB01992	3-hydroxy-3-methylglutaryl-CoA reductase	experimental	Coenzyme A	CC(C)(CO[P@](O)(=O)O[P@@](O)(=O)OC[C@@H]1O[C@H]([C@H](O)[C@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N)[C@@H](O)C(=O)NCCC(=O)NCCS
HMGCR	DB03431	3-hydroxy-3-methylglutaryl-CoA reductase	experimental	Adenosine-5'-Diphosphate	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](CO[P@](O)(=O)OP(O)(O)=O)[C@H](O)[C@H]1O
HMGCR	DB03461	3-hydroxy-3-methylglutaryl-CoA reductase	experimental	2'-Monophosphoadenosine 5'-Diphosphoribose	NC(=O)C1=CC=C[N+](=C1)[C@@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@@H]2O[C@H]([C@H](OP(O)(O)=O)[C@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@H]1O
HMGCR	DB04377	3-hydroxy-3-methylglutaryl-CoA reductase	experimental	3-Hydroxy-3-Methyl-Glutaric Acid	CC(O)(CC(O)=O)CC(O)=O
HMGCR	DB04447	3-hydroxy-3-methylglutaryl-CoA reductase	experimental	1,4-Dithiothreitol	O[C@H](CS)[C@H](O)CS
HMGCR	DB06693	3-hydroxy-3-methylglutaryl-CoA reductase	experimental	Mevastatin	CC[C@H](C)C(=O)O[C@H]1CCC=C2C=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC(O)=O)[C@@H]12
HMGCR	DB06846	3-hydroxy-3-methylglutaryl-CoA reductase	experimental	7-[3-(4-FLUORO-PHENYL)-1-ISOPROPYL-1H-INDOL-2-YL]-3,5-DIHYDROXY-HEPTANOIC ACID	CC(C)N1C(CC[C@@H](O)C[C@@H](O)CC(O)=O)=C(C2=C1C=CC=C2)C1=CC=C(F)C=C1
HMGCR	DB01907	3-hydroxy-3-methylglutaryl-CoA reductase	experimental	Nicotinamide-Adenine-Dinucleotide	NC(=O)C1=CC=C[N+](=C1)[C@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@@H]1O
HMGCR	DB03518	3-hydroxy-3-methylglutaryl-CoA reductase	experimental	(R)-Mevalonate	C[C@@](O)(CCO)CC([O-])=O
HMGCR	DB03785	3-hydroxy-3-methylglutaryl-CoA reductase	experimental	(3r,5r)-7-((1r,2r,6s,8r,8as)-2,6-Dimethyl-8-{[(2r)-2-Methylbutanoyl]Oxy}-1,2,6,7,8,8a-Hexahydronaphthalen-1-Yl)-3,5-Dihydroxyheptanoic Acid	CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC(O)=O)[C@@H]12
HMGCR	DB00363	3-hydroxy-3-methylglutaryl-CoA reductase	approved	Clozapine	CN1CCN(CC1)C1=NC2=CC(Cl)=CC=C2NC2=CC=CC=C12
HMGCR	DB00502	3-hydroxy-3-methylglutaryl-CoA reductase	approved	Haloperidol	OC1(CCN(CCCC(=O)C2=CC=C(F)C=C2)CC1)C1=CC=C(Cl)C=C1
HMGCR	DB00264	3-hydroxy-3-methylglutaryl-CoA reductase	approved; investigational	Metoprolol	COCCC1=CC=C(OCC(O)CNC(C)C)C=C1
HMGCS1	DB00363	3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)	approved	Clozapine	CN1CCN(CC1)C1=NC2=CC(Cl)=CC=C2NC2=CC=CC=C12
HMGCS1	DB00502	3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)	approved	Haloperidol	OC1(CCN(CCCC(=O)C2=CC=C(F)C=C2)CC1)C1=CC=C(Cl)C=C1
HMOX1	DB00157	heme oxygenase (decycling) 1	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
HMOX1	DB01942	heme oxygenase (decycling) 1	experimental	Formic Acid	OC=O
HMOX1	DB02073	heme oxygenase (decycling) 1	experimental	Biliverdine Ix Alpha	CC1=C(C=C)\C(NC1=O)=C\C1=N\C(=C/c2nc(\C=C3\NC(=O)C(C=C)=C3C)c(C)c2CCC(O)=O)\C(CCC(O)=O)=C1C
HMOX1	DB02468	heme oxygenase (decycling) 1	experimental	12-Phenylheme	C[C@H]1[C@H](C=C)C2=CC3=C(C)C(CCC(O)=O)=C4C=C5C(CCC(O)=O)=C(C)C6=[N+]5[Fe]5(N34)N3C(=C6)C(C)=C(C=C)C3=C(C1=[N+]25)C1=CC=CC=C1
HMOX1	DB03014	heme oxygenase (decycling) 1	experimental	Heme	CC1=C(CCC(O)=O)C2=CC3=[N+]4C(=CC5=C(C=C)C(C)=C6C=C7C(C=C)=C(C)C8=[N+]7[Fe@]4(N2C1=C8)N56)C(C)=C3CCC(O)=O
HMOX1	DB03906	heme oxygenase (decycling) 1	experimental	2-Phenylheme	CC1=C(C=C)C2=CC3=[N+]4C(=CC5=C(C)C(CCC(O)=O)=C6N5[Fe]44N2C1=CC1=[N+]4C(C(CCC(O)=O)=C1C)=C6C1=CC=CC=C1)C(C=C)=C3C
HMOX1	DB04803	heme oxygenase (decycling) 1	experimental	Verdoheme	[Fe+4].CC(=C)\C1=N\C=C/C2=C(CCC(O)=O)C(C)=C([N-]2)\C=C2/N=C(/[O+]=C3\[N-]\C(=C/1)C(C)=C3C=C)C(C)=C2C=C
HMOX1	DB06914	heme oxygenase (decycling) 1	experimental	1-({2-[2-(4-CHLOROPHENYL)ETHYL]-1,3-DIOXOLAN-2-YL}METHYL)-1H-IMIDAZOLE	ClC1=CC=C(CCC2(CN3C=CN=C3)OCCO2)C=C1
HMOX1	DB07342	heme oxygenase (decycling) 1	experimental	1-(adamantan-1-yl)-2-(1H-imidazol-1-yl)ethanone	O=C(CN1C=CN=C1)C12CC3CC(CC(C3)C1)C2
HMOX2	DB00157	heme oxygenase (decycling) 2	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
HMOX2	DB03014	heme oxygenase (decycling) 2	experimental	Heme	CC1=C(CCC(O)=O)C2=CC3=[N+]4C(=CC5=C(C=C)C(C)=C6C=C7C(C=C)=C(C)C8=[N+]7[Fe@]4(N2C1=C8)N56)C(C)=C3CCC(O)=O
HNMT	DB00613	histamine N-methyltransferase	approved	Amodiaquine	CCN(CC)CC1=C(O)C=CC(NC2=C3C=CC(Cl)=CC3=NC=C2)=C1
HNMT	DB01752	histamine N-methyltransferase	experimental	S-Adenosyl-L-Homocysteine	N[C@@H](CCSC[C@@H]1O[C@H]([C@H](O)[C@H]1O)N1C=NC2=C1N=CN=C2N)C(O)=O
HNMT	DB04655	histamine N-methyltransferase	experimental	METOPRINE, METHODICHLOROPHEN	CC1=C(C(N)=NC(N)=N1)C1=CC(Cl)=C(Cl)C=C1
HNMT	DB07106	histamine N-methyltransferase	experimental	4-(DIMETHYLAMINO)BUTYL IMIDOTHIOCARBAMATE	CN(C)CCCCSC(N)=N
HNMT	DB01454	histamine N-methyltransferase	illicit; experimental	3,4-Methylenedioxymethamphetamine	CNC(C)CC1=CC2=C(OCO2)C=C1
HNMT	DB00668	histamine N-methyltransferase	approved	Epinephrine	CNC[C@H](O)C1=CC(O)=C(O)C=C1
HNMT	DB01033	histamine N-methyltransferase	approved	Mercaptopurine	S=C1N=CNC2=C1NC=N2
HNMT	DB00667	histamine N-methyltransferase	approved	Histamine Phosphate	OP(O)(O)=O.OP(O)(O)=O.NCCC1=CN=CN1
HPD	DB00143	4-hydroxyphenylpyruvate dioxygenase	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
HPD	DB00120	4-hydroxyphenylpyruvate dioxygenase	approved; nutraceutical	L-Phenylalanine	N[C@@H](CC1=CC=CC=C1)C(O)=O
HPD	DB00135	4-hydroxyphenylpyruvate dioxygenase	approved; nutraceutical	L-Tyrosine	N[C@@H](CC1=CC=C(O)C=C1)C(O)=O
HPD	DB00360	4-hydroxyphenylpyruvate dioxygenase	approved; investigational	Tetrahydrobiopterin	CC(O)C(O)C1CNC2=C(N1)C(=O)N=C(N)N2
HPGDS	DB00143	hematopoietic prostaglandin D synthase	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
HPGDS	DB01897	hematopoietic prostaglandin D synthase	experimental	2-(2f-Benzothiazolyl)-5-Styryl-3-(4f-Phthalhydrazidyl)Tetrazolium Chloride	O=C1NNC(=O)C2=CC(=CC=C12)[N+]1=NC(\C=C\C2=CC=CC=C2)=NN1C1=NC2=C(S1)C=CC=C2
HPGDS	DB04077	hematopoietic prostaglandin D synthase	experimental	Glycerol	OCC(O)CO
HPGDS	DB07613	hematopoietic prostaglandin D synthase	experimental	3-phenyl-5-(1H-pyrazol-3-yl)isoxazole	N1C=CC(=N1)C1=CC(=NO1)C1=CC=CC=C1
HPGDS	DB07614	hematopoietic prostaglandin D synthase	experimental	PHENYL-5-(1H-PYRAZOL-3-YL)-1,3-THIAZOLE	N1C=CC(=N1)C1=CN=C(S1)C1=CC=CC=C1
HPGDS	DB07615	hematopoietic prostaglandin D synthase	experimental	2-{[(2E)-3-(3,4-dimethoxyphenyl)prop-2-enoyl]amino}benzoic acid	COC1=CC=C(\C=C\C(=O)NC2=CC=CC=C2C(O)=O)C=C1OC
HPGDS	DB07616	hematopoietic prostaglandin D synthase	experimental	4-{[4-(4-fluoro-3-methylphenyl)-1,3-thiazol-2-yl]amino}-2-hydroxybenzoic acid	CC1=CC(=CC=C1F)C1=CSC(NC2=CC=C(C(O)=O)C(O)=C2)=N1
HPGDS	DB07917	hematopoietic prostaglandin D synthase	experimental	4-(BENZHYDRYLOXY)-1-[3-(1H-TETRAAZOL-5-YL)PROPYL]PIPERIDINE	C(CN1CCC(CC1)OC(C1=CC=CC=C1)C1=CC=CC=C1)CC1=NN=NN1
HPGDS	DB08313	hematopoietic prostaglandin D synthase	experimental	nocodazole	COC(=O)NC1=NC2=CC=C(C=C2N1)C(=O)C1=CC=CS1
HPGDS	DB08695	hematopoietic prostaglandin D synthase	experimental	3-(4-nitrophenyl)-1H-pyrazole	[O-][N+](=O)C1=CC=C(C=C1)C1=NNC=C1
HPGDS	DB08790	hematopoietic prostaglandin D synthase	experimental	1-PHENYL-1H-PYRAZOLE-4-CARBOXYLIC ACID	OC(=O)C1=CN(N=C1)C1=CC=CC=C1
HPRT1	DB00993	hypoxanthine phosphoribosyltransferase 1	approved	Azathioprine	CN1C=NC(=C1SC1=NC=NC2=C1NC=N2)[N+]([O-])=O
HPRT1	DB01033	hypoxanthine phosphoribosyltransferase 1	approved	Mercaptopurine	S=C1N=CNC2=C1NC=N2
HPRT1	DB01632	hypoxanthine phosphoribosyltransferase 1	experimental	Alpha-Phosphoribosylpyrophosphoric Acid	O[C@H]1[C@@H](O)[C@@H](O[P@](O)(=O)OP(O)(O)=O)O[C@@H]1COP(O)(O)=O
HPRT1	DB02212	hypoxanthine phosphoribosyltransferase 1	experimental	Pyrophosphate 2-	O[P@]([O-])(=O)O[P@@](O)([O-])=O
HPRT1	DB02309	hypoxanthine phosphoribosyltransferase 1	experimental	5--Monophosphate-9-Beta-D-Ribofuranosyl Xanthine	O[C@H]1[C@H](COP(O)(O)=O)O[C@H]([C@@H]1O)N1C=[NH+]C2=C1NC(=O)NC2=O
HPRT1	DB03153	hypoxanthine phosphoribosyltransferase 1	experimental	3h-Pyrazolo[4,3-D]Pyrimidin-7-Ol	OC1=NC=NC2=C1N=NC2
HPRT1	DB04356	hypoxanthine phosphoribosyltransferase 1	experimental	9-Deazaguanine	NC1=Nc2ccnc2C(=O)N1
HPRT1	DB00173	hypoxanthine phosphoribosyltransferase 1	approved; nutraceutical	Adenine	NC1=C2NC=NC2=NC=N1
HPRT1	DB00640	hypoxanthine phosphoribosyltransferase 1	approved; investigational	Adenosine	NC1=C2N=CN([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)C2=NC=N1
HPRT1	DB00515	hypoxanthine phosphoribosyltransferase 1	approved	Cisplatin	N[Pt](N)(Cl)Cl
HPRT1	DB00441	hypoxanthine phosphoribosyltransferase 1	approved	Gemcitabine	NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](CO)[C@@H](O)C1(F)F
HPRT1	DB00352	hypoxanthine phosphoribosyltransferase 1	approved	Thioguanine	NC1=NC(=S)C2=C(N1)N=CN2
HPRT1	DB00563	hypoxanthine phosphoribosyltransferase 1	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
HS3ST3A1	DB01812	heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1	experimental	Adenosine-3'-5'-Diphosphate	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](COP(O)(O)=O)[C@H](OP(O)(O)=O)[C@H]1O
HS3ST3A1	DB02264	heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1	experimental	O2-Sulfo-Glucuronic Acid	O[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1OS(O)(=O)=O)C(O)=O
HS3ST3A1	DB03959	heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1	experimental	N,O6-Disulfo-Glucosamine	O[C@H]1O[C@@H](COS(O)(=O)=O)[C@H](O)[C@@H](O)[C@@H]1NS(O)(=O)=O
HS3ST3A1	DB03981	heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1	experimental	1,4-Dideoxy-5-Dehydro-O2-Sulfo-Glucuronic Acid	O[C@@H]1C=C(OC[C@H]1OS(O)(=O)=O)C(O)=O
HS3ST3A1	DB04272	heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1	experimental	Citric Acid	OC(=O)CC(O)(CC(O)=O)C(O)=O
HSD11B1	DB00157	hydroxysteroid (11-beta) dehydrogenase 1	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
HSD11B1	DB02329	hydroxysteroid (11-beta) dehydrogenase 1	experimental	Carbenoxolone	CC1(C)[C@@H](CC[C@]2(C)[C@@H]1CC[C@]1(C)[C@H]2C(=O)C=C2[C@@H]3C[C@@](C)(CC[C@@]3(C)CC[C@@]12C)C(O)=O)OC(=O)CCC(O)=O
HSD11B1	DB03461	hydroxysteroid (11-beta) dehydrogenase 1	experimental	2'-Monophosphoadenosine 5'-Diphosphoribose	NC(=O)C1=CC=C[N+](=C1)[C@@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@@H]2O[C@H]([C@H](OP(O)(O)=O)[C@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@H]1O
HSD11B1	DB03814	hydroxysteroid (11-beta) dehydrogenase 1	experimental	2-(N-Morpholino)-Ethanesulfonic Acid	[O-]S(=O)(=O)CC[NH+]1CCOCC1
HSD11B1	DB04652	hydroxysteroid (11-beta) dehydrogenase 1	experimental	(11-BETA)-11,21-DIHYDROXY-PREGN-4-ENE-3,20-DIONE	C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)CO
HSD11B1	DB06992	hydroxysteroid (11-beta) dehydrogenase 1	experimental	(3,3-dimethylpiperidin-1-yl)(6-(3-fluoro-4-methylphenyl)pyridin-2-yl)methanone	CC1=CC=C(C=C1F)C1=NC(=CC=C1)C(=O)N1CCCC(C)(C)C1
HSD11B1	DB07017	hydroxysteroid (11-beta) dehydrogenase 1	experimental	(5S)-2-{[(1S)-1-(4-fluorophenyl)ethyl]amino}-5-(1-hydroxy-1-methylethyl)-5-methyl-1,3-thiazol-4(5H)-one	C[C@H](NC1=NC(=O)[C@@](C)(S1)C(C)(C)O)C1=CC=C(F)C=C1
HSD11B1	DB07049	hydroxysteroid (11-beta) dehydrogenase 1	experimental	(2R)-1-[(4-tert-butylphenyl)sulfonyl]-2-methyl-4-(4-nitrophenyl)piperazine	C[C@@H]1CN(CCN1S(=O)(=O)C1=CC=C(C=C1)C(C)(C)C)C1=CC=C(C=C1)[N+]([O-])=O
HSD11B1	DB07056	hydroxysteroid (11-beta) dehydrogenase 1	experimental	2-(6-{[(3-chloro-2-methylphenyl)sulfonyl]amino}pyridin-2-yl)-N,N-diethylacetamide	CCN(CC)C(=O)CC1=CC=CC(NS(=O)(=O)C2=C(C)C(Cl)=CC=C2)=N1
HSD11B1	DB07310	hydroxysteroid (11-beta) dehydrogenase 1	experimental	(5S)-2-{[(1S)-1-(2-fluorophenyl)ethyl]amino}-5-methyl-5-(trifluoromethyl)-1,3-thiazol-4(5H)-one	C[C@H](NC1=NC(=O)[C@](C)(S1)C(F)(F)F)C1=C(F)C=CC=C1
HSD11B1	DB07316	hydroxysteroid (11-beta) dehydrogenase 1	experimental	N-{1-[(1-carbamoylcyclopropyl)methyl]piperidin-4-yl}-N-cyclopropyl-4-[(1S)-2,2,2-trifluoro-1-hydroxy-1-methylethyl]benzamide	C[C@](O)(C1=CC=C(C=C1)C(=O)N(C1CC1)C1CCN(CC2(CC2)C(N)=O)CC1)C(F)(F)F
HSD11B1	DB07619	hydroxysteroid (11-beta) dehydrogenase 1	experimental	N-cyclopropyl-N-(trans-4-pyridin-3-ylcyclohexyl)-4-[(1S)-2,2,2-trifluoro-1-hydroxy-1-methylethyl]benzamide	C[C@](O)(C1=CC=C(C=C1)C(=O)N(C1CC1)[C@H]1CC[C@@H](CC1)C1=CC=CN=C1)C(F)(F)F
HSD11B1	DB07624	hydroxysteroid (11-beta) dehydrogenase 1	experimental	1-{[(3R)-3-methyl-4-({4-[(1S)-2,2,2-trifluoro-1-hydroxy-1-methylethyl]phenyl}sulfonyl)piperazin-1-yl]methyl}cyclopropanecarboxamide	C[C@@H]1CN(CC2(CC2)C(N)=O)CCN1S(=O)(=O)C1=CC=C(C=C1)[C@](C)(O)C(F)(F)F
HSD11B1	DB07866	hydroxysteroid (11-beta) dehydrogenase 1	experimental	(5S)-2-(cyclooctylamino)-5-methyl-5-propyl-1,3-thiazol-4(5H)-one	CCC[C@]1(C)SC(NC2CCCCCCC2)=NC1=O
HSD11B1	DB08277	hydroxysteroid (11-beta) dehydrogenase 1	experimental	2-(2-CHLORO-4-FLUOROPHENOXY)-2-METHYL-N-[(1R,2S,3S,5S,7S)-5-(METHYLSULFONYL)-2-ADAMANTYL]PROPANAMIDE	CC(C)(OC1=C(Cl)C=C(F)C=C1)C(=O)N[C@H]1[C@H]2C[C@H]3C[C@@H]1C[C@](C3)(C2)S(C)(=O)=O
HSD11B1	DB08280	hydroxysteroid (11-beta) dehydrogenase 1	experimental	(1S,3R,4S,5S,7S)-4-{[2-(4-METHOXYPHENOXY)-2-METHYLPROPANOYL]AMINO}ADAMANTANE-1-CARBOXAMIDE	COC1=CC=C(OC(C)(C)C(=O)N[C@H]2[C@H]3C[C@H]4C[C@@H]2C[C@](C4)(C3)C(N)=O)C=C1
HSD11B1	DB08771	hydroxysteroid (11-beta) dehydrogenase 1	experimental	(5R)-2-[(2-fluorophenyl)amino]-5-(1-methylethyl)-1,3-thiazol-4(5H)-one	CC(C)[C@H]1SC(NC2=C(F)C=CC=C2)=NC1=O
HSD11B1	DB00741	hydroxysteroid (11-beta) dehydrogenase 1	approved	Hydrocortisone	C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
HSD11B1	DB01132	hydroxysteroid (11-beta) dehydrogenase 1	approved; investigational	Pioglitazone	CCC1=CN=C(CCOC2=CC=C(CC3SC(=O)NC3=O)C=C2)C=C1
HSD11B1	DB00412	hydroxysteroid (11-beta) dehydrogenase 1	approved; investigational	Rosiglitazone	CN(CCOC1=CC=C(CC2SC(=O)NC2=O)C=C1)C1=CC=CC=N1
HSD11B1	DB00197	hydroxysteroid (11-beta) dehydrogenase 1	withdrawn	Troglitazone	CC1=C(C)C2=C(CCC(C)(COC3=CC=C(CC4SC(=O)NC4=O)C=C3)O2)C(C)=C1O
HSD11B1	DB00635	hydroxysteroid (11-beta) dehydrogenase 1	approved	Prednisone	C[C@]12CC(=O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
HSD17B1	DB00157	hydroxysteroid (17-beta) dehydrogenase 1	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
HSD17B1	DB01536	hydroxysteroid (17-beta) dehydrogenase 1	illicit; experimental	4-Androstenedione	C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CCC2=O
HSD17B1	DB01561	hydroxysteroid (17-beta) dehydrogenase 1	illicit; experimental	Androstanedione	C[C@]12CC[C@H]3[C@@H](CC[C@H]4CC(=O)CC[C@]34C)[C@@H]1CCC2=O
HSD17B1	DB01708	hydroxysteroid (17-beta) dehydrogenase 1	nutraceutical	Dehydroepiandrosterone	C[C@]12CC[C@H]3[C@@H](CC=C4C[C@@H](O)CC[C@]34C)[C@@H]1CCC2=O
HSD17B1	DB01907	hydroxysteroid (17-beta) dehydrogenase 1	experimental	Nicotinamide-Adenine-Dinucleotide	NC(=O)C1=CC=C[N+](=C1)[C@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@@H]1O
HSD17B1	DB02187	hydroxysteroid (17-beta) dehydrogenase 1	experimental	Equilin	C[C@]12CC[C@H]3C(=CCC4=C3C=CC(O)=C4)[C@@H]1CCC2=O
HSD17B1	DB02323	hydroxysteroid (17-beta) dehydrogenase 1	experimental	EM-1745	C[C@]12CC[C@H]3[C@@H](CCC4=CC(O)=CC=C34)[C@@H]1C[C@@H](CCCCCCCCC(=O)OC[C@@H]1O[C@H]([C@H](O)[C@H]1O)N1C=NC3=C1N=CN=C3N)[C@H]2O
HSD17B1	DB02901	hydroxysteroid (17-beta) dehydrogenase 1	illicit; experimental	Dihydrotestosterone	CC12CCC3C(CCC4CC(=O)CCC34C)C1CCC2O
HSD17B1	DB03461	hydroxysteroid (17-beta) dehydrogenase 1	experimental	2'-Monophosphoadenosine 5'-Diphosphoribose	NC(=O)C1=CC=C[N+](=C1)[C@@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@@H]2O[C@H]([C@H](OP(O)(O)=O)[C@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@H]1O
HSD17B10	DB00157	hydroxysteroid (17-beta) dehydrogenase 10	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
HSD17B10	DB01907	hydroxysteroid (17-beta) dehydrogenase 10	experimental	Nicotinamide-Adenine-Dinucleotide	NC(=O)C1=CC=C[N+](=C1)[C@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@@H]1O
HSD17B10	DB02820	hydroxysteroid (17-beta) dehydrogenase 10	experimental	1-Azepan-1-Yl-2-Phenyl-2-(4-Thioxo-1,4-Dihydro-Pyrazolo[3,4-D]Pyrimidin-5-Yl)Ethanone Adduct	NC(=O)C1=CN(C=C[C@H]1N1C=C2C(=N1)N=CN([C@@H](C(=O)N1CCCCCC1)C1=CC=CC=C1)C2=S)[C@@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@]([O-])(=O)OC[C@@H]2O[C@H]([C@H]([O-])[C@H]2[O-])N2C=NC3=C2N=CN=C3N)[C@H](O)[C@H]1O
HSD17B3	DB00157	hydroxysteroid (17-beta) dehydrogenase 3	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
HSD17B3	DB00396	hydroxysteroid (17-beta) dehydrogenase 3	approved	Progesterone	CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C
HSD17B3	DB00624	hydroxysteroid (17-beta) dehydrogenase 3	approved; investigational	Testosterone	C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CC[C@@H]2O
HSD17B4	DB00157	hydroxysteroid (17-beta) dehydrogenase 4	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
HSD17B4	DB01907	hydroxysteroid (17-beta) dehydrogenase 4	experimental	Nicotinamide-Adenine-Dinucleotide	NC(=O)C1=CC=C[N+](=C1)[C@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@@H]1O
HSD17B4	DB03192	hydroxysteroid (17-beta) dehydrogenase 4	experimental	3r-Hydroxydecanoyl-Coa	CCCCCCC[C@H](O)CC(=O)SCCNC(=O)CCNC(=O)[C@@H](O)C(C)(C)CO[P@](O)(=O)O[P@@](O)(=O)OC[C@@H]1O[C@H]([C@H](O)[C@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N
HSD17B4	DB00145	hydroxysteroid (17-beta) dehydrogenase 4	approved; nutraceutical	Glycine	NCC(O)=O
HSD17B7	DB00157	hydroxysteroid (17-beta) dehydrogenase 7	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
HSD3B1	DB00157	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
HSD3B1	DB01108	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1	approved; withdrawn; investigational	Trilostane	C[C@]12CC[C@H]3[C@@H](CC[C@@]45O[C@@H]4C(O)=C(C[C@]35C)C#N)[C@@H]1CC[C@@H]2O
HSD3B1	DB01536	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1	illicit; experimental	4-Androstenedione	C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CCC2=O
HSD3B2	DB00157	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
HSD3B2	DB01108	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2	approved; withdrawn; investigational	Trilostane	C[C@]12CC[C@H]3[C@@H](CC[C@@]45O[C@@H]4C(O)=C(C[C@]35C)C#N)[C@@H]1CC[C@@H]2O
HSD3B7	DB00145	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7	approved; nutraceutical	Glycine	NCC(O)=O
HSPA8	DB03431	heat shock 70kDa protein 8	experimental	Adenosine-5'-Diphosphate	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](CO[P@](O)(=O)OP(O)(O)=O)[C@H](O)[C@H]1O
HSPA8	DB07045	heat shock 70kDa protein 8	experimental	(2R,3R,4S,5R)-2-[6-amino-8-[(3,4-dichlorophenyl)methylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol	NC1=C2N=C(NCC3=CC=C(Cl)C(Cl)=C3)N([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)C2=NC=N1
HSPA8	DB00458	heat shock 70kDa protein 8	approved	Imipramine	CN(C)CCCN1C2=CC=CC=C2CCC2=CC=CC=C12
HSPB1	DB00125	heat shock 27kDa protein 1	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
HSPB1	DB00435	heat shock 27kDa protein 1	approved	Nitric Oxide	[N]=O
HSPB1	DB00269	heat shock 27kDa protein 1	approved	Chlorotrianisene	COC1=CC=C(C=C1)C(Cl)=C(C1=CC=C(OC)C=C1)C1=CC=C(OC)C=C1
HSPB1	DB00286	heat shock 27kDa protein 1	approved	Conjugated Estrogens	[Na+].C[C@]12CC[C@H]3[C@@H](CCC4=CC(OS([O-])(=O)=O)=CC=C34)[C@@H]1CCC2=O
HSPB1	DB00890	heat shock 27kDa protein 1	approved	Dienestrol	CC=C(C(=CC)C1=CC=C(O)C=C1)C1=CC=C(O)C=C1
HSPB1	DB00255	heat shock 27kDa protein 1	approved	Diethylstilbestrol	CCC(=C(CC)C1=CC=C(O)C=C1)C1=CC=C(O)C=C1
HSPB1	DB00783	heat shock 27kDa protein 1	approved; investigational	Estradiol	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CC[C@@H]2O
HSPB1	DB00655	heat shock 27kDa protein 1	approved	Estrone	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CCC2=O
HSPB1	DB00977	heat shock 27kDa protein 1	approved	Ethinyl Estradiol	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CC[C@@]2(O)C#C
HSPB1	DB00143	heat shock 27kDa protein 1	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
IDH1	DB01727	isocitrate dehydrogenase 1 (NADP+), soluble	experimental	Isocitric Acid	O[C@@H]([C@H](CC(O)=O)C(O)=O)C(O)=O
IDH1	DB03461	isocitrate dehydrogenase 1 (NADP+), soluble	experimental	2'-Monophosphoadenosine 5'-Diphosphoribose	NC(=O)C1=CC=C[N+](=C1)[C@@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@@H]2O[C@H]([C@H](OP(O)(O)=O)[C@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@H]1O
IDH3A	DB00157	isocitrate dehydrogenase 3 (NAD+) alpha	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
IDH3B	DB00157	isocitrate dehydrogenase 3 (NAD+) beta	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
IDH3G	DB00157	isocitrate dehydrogenase 3 (NAD+) gamma	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
IDI1	DB01785	isopentenyl-diphosphate delta isomerase 1	experimental	Dimethylallyl Diphosphate	CC(C)=CCO[P@](O)(=O)OP(O)(O)=O
IMPA1	DB01356	inositol(myo)-1(or 4)-monophosphatase 1	approved	Lithium	[Li+]
IMPA1	DB03542	inositol(myo)-1(or 4)-monophosphatase 1	experimental	L-Myo-Inositol-1-Phosphate	O[C@H]1[C@H](O)[C@@H](O)[C@H](OP([O-])([O-])=O)[C@@H](O)[C@@H]1O
IMPA2	DB01356	inositol(myo)-1(or 4)-monophosphatase 2	approved	Lithium	[Li+]
IMPDH1	DB00157	IMP (inosine 5'-monophosphate) dehydrogenase 1	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
IMPDH1	DB00688	IMP (inosine 5'-monophosphate) dehydrogenase 1	approved; investigational	Mycophenolate mofetil	COC1=C(C\C=C(/C)CCC(=O)OCCN2CCOCC2)C(O)=C2C(=O)OCC2=C1C
IMPDH1	DB00811	IMP (inosine 5'-monophosphate) dehydrogenase 1	approved	Ribavirin	NC(=O)C1=NN(C=N1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
IMPDH1	DB01024	IMP (inosine 5'-monophosphate) dehydrogenase 1	approved	Mycophenolic acid	COC1=C(C\C=C(/C)CCC(O)=O)C(O)=C2C(=O)OCC2=C1C
IMPDH1	DB03948	IMP (inosine 5'-monophosphate) dehydrogenase 1	experimental	6-Chloropurine Riboside, 5'-Monophosphate	O[C@H]1[C@H](COP(O)(O)=O)O[C@H]([C@@H]1O)N1C=NC2=C1N=C[NH+]=C2Cl
IMPDH1	DB00993	IMP (inosine 5'-monophosphate) dehydrogenase 1	approved	Azathioprine	CN1C=NC(=C1SC1=NC=NC2=C1NC=N2)[N+]([O-])=O
IMPDH2	DB00157	IMP (inosine 5'-monophosphate) dehydrogenase 2	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
IMPDH2	DB00688	IMP (inosine 5'-monophosphate) dehydrogenase 2	approved; investigational	Mycophenolate mofetil	COC1=C(C\C=C(/C)CCC(=O)OCCN2CCOCC2)C(O)=C2C(=O)OCC2=C1C
IMPDH2	DB01024	IMP (inosine 5'-monophosphate) dehydrogenase 2	approved	Mycophenolic acid	COC1=C(C\C=C(/C)CCC(O)=O)C(O)=C2C(=O)OCC2=C1C
IMPDH2	DB01693	IMP (inosine 5'-monophosphate) dehydrogenase 2	experimental	Ribavirin Monophosphate	NC(=O)C1=NN(C=N1)[C@@H]1O[C@@H](COP(O)(O)=O)[C@H](O)[C@H]1O
IMPDH2	DB01907	IMP (inosine 5'-monophosphate) dehydrogenase 2	experimental	Nicotinamide-Adenine-Dinucleotide	NC(=O)C1=CC=C[N+](=C1)[C@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@@H]1O
IMPDH2	DB03070	IMP (inosine 5'-monophosphate) dehydrogenase 2	experimental	Selenazole-4-Carboxyamide-Adenine Dinucleotide	NC(=O)C1=C[Se]C(=N1)[C@@H]1O[C@@H](CO[P@](O)(=O)O[P@@](O)(=O)OC[C@@H]2O[C@H]([C@H](O)[C@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@H]1O
IMPDH2	DB03948	IMP (inosine 5'-monophosphate) dehydrogenase 2	experimental	6-Chloropurine Riboside, 5'-Monophosphate	O[C@H]1[C@H](COP(O)(O)=O)O[C@H]([C@@H]1O)N1C=NC2=C1N=C[NH+]=C2Cl
IMPDH2	DB04566	IMP (inosine 5'-monophosphate) dehydrogenase 2	experimental	Inosinic Acid	O[C@H]1[C@H](COP(O)(O)=O)O[C@H]([C@@H]1O)N1C=NC2=C1N=CNC2=O
IMPDH2	DB00993	IMP (inosine 5'-monophosphate) dehydrogenase 2	approved	Azathioprine	CN1C=NC(=C1SC1=NC=NC2=C1NC=N2)[N+]([O-])=O
IMPDH2	DB00158	IMP (inosine 5'-monophosphate) dehydrogenase 2	approved; nutraceutical	Folic Acid	NC1=NC(=O)C2=NC(CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)=CN=C2N1
IMPDH2	DB00563	IMP (inosine 5'-monophosphate) dehydrogenase 2	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
INHA	DB00609	inhibin, alpha	approved	Ethionamide	CCC1=NC=CC(=C1)C(N)=S
INHA	DB00951	inhibin, alpha	approved	Isoniazid	NNC(=O)C1=CC=NC=C1
INHA	DB01907	inhibin, alpha	experimental	Nicotinamide-Adenine-Dinucleotide	NC(=O)C1=CC=C[N+](=C1)[C@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@@H]1O
INHA	DB02990	inhibin, alpha	experimental	C16-Fatty-Acyl-Substrate-Mimic	CCCCCCCCCCCCCCCC(=O)SCCNC(C)=O
INHA	DB04289	inhibin, alpha	experimental	Genz-10850	O=C(N1CCN(CC1)C1C2=CC=CC=C2C2=CC=CC=C12)C1=CC2=C(NC=C2)C=C1
INHA	DB07090	inhibin, alpha	experimental	(3S)-N-(3-CHLORO-2-METHYLPHENYL)-1-CYCLOHEXYL-5-OXOPYRROLIDINE-3-CARBOXAMIDE	CC1=C(NC(=O)[C@@H]2CN(C3CCCCC3)C(=O)C2)C=CC=C1Cl
INHA	DB07123	inhibin, alpha	experimental	N-(4-METHYLBENZOYL)-4-BENZYLPIPERIDINE	CC1=CC=C(C=C1)C(=O)N1CCC(CC2=CC=CC=C2)CC1
INHA	DB07155	inhibin, alpha	experimental	(3S)-1-CYCLOHEXYL-5-OXO-N-PHENYLPYRROLIDINE-3-CARBOXAMIDE	O=C(NC1=CC=CC=C1)[C@@H]1CN(C2CCCCC2)C(=O)C1
INHA	DB07178	inhibin, alpha	experimental	5-PENTYL-2-PHENOXYPHENOL	CCCCCC1=CC(O)=C(OC2=CC=CC=C2)C=C1
INHA	DB07188	inhibin, alpha	experimental	(3S)-1-CYCLOHEXYL-N-(3,5-DICHLOROPHENYL)-5-OXOPYRROLIDINE-3-CARBOXAMIDE	ClC1=CC(NC(=O)[C@@H]2CN(C3CCCCC3)C(=O)C2)=CC(Cl)=C1
INHA	DB07192	inhibin, alpha	experimental	(3S)-N-(3-BROMOPHENYL)-1-CYCLOHEXYL-5-OXOPYRROLIDINE-3-CARBOXAMIDE	BrC1=CC(NC(=O)[C@@H]2CN(C3CCCCC3)C(=O)C2)=CC=C1
INHA	DB07222	inhibin, alpha	experimental	(3S)-N-(5-CHLORO-2-METHYLPHENYL)-1-CYCLOHEXYL-5-OXOPYRROLIDINE-3-CARBOXAMIDE	CC1=C(NC(=O)[C@@H]2CN(C3CCCCC3)C(=O)C2)C=C(Cl)C=C1
INHA	DB07287	inhibin, alpha	experimental	2-(2,4-DICHLOROPHENOXY)-5-(PYRIDIN-2-YLMETHYL)PHENOL	OC1=CC(CC2=CC=CC=N2)=CC=C1OC1=CC=C(Cl)C=C1Cl
INHA	DB08604	inhibin, alpha	experimental	TRICLOSAN	OC1=C(OC2=C(Cl)C=C(Cl)C=C2)C=CC(Cl)=C1
INHA	DB04393	inhibin, alpha	experimental	Diclosan	OC1=C(OC2=CC=C(Cl)C=C2)C=CC(Cl)=C1
INHA	DB01691	inhibin, alpha	experimental	Indole Naphthyridinone	CN(CC1=CN(C)C2=CC=CC=C12)C(=O)\C=C\C1=CN=C2NC(=O)CCC2=C1
INHA	DB01865	inhibin, alpha	experimental	3-(6-Aminopyridin-3-Yl)-N-Methyl-N-[(1-Methyl-1h-Indol-2-Yl)Methyl]Acrylamide	CN(CC1=CC2=C(C=CC=C2)N1C)C(=O)\C=C\C1=CN=C(N)C=C1
INHA	DB02379	inhibin, alpha	experimental	Beta-D-Glucose	OC[C@@H]1O[C@H](O)[C@@H](O)[C@H](O)[C@H]1O
INHA	DB03030	inhibin, alpha	experimental	4-(2-Thienyl)-1-(4-Methylbenzyl)-1h-Imidazole	CC1=CC=C(CN2C=NC(=C2)C2=CC=CS2)C=C1
INHA	DB03534	inhibin, alpha	experimental	3-[(Acetyl-Methyl-Amino)-Methyl]-4-Amino-N-Methyl-N-(1-Methyl-1h-Indol-2-Ylmethyl)-Benzamide	CN(CC1=C(N)C=CC(=C1)C(=O)N(C)CC1=CC2=C(C=CC=C2)N1C)C(C)=O
INHA	DB04030	inhibin, alpha	experimental	1,3,4,9-Tetrahydro-2-(Hydroxybenzoyl)-9-[(4-Hydroxyphenyl)Methyl]-6-Methoxy-2h-Pyrido[3,4-B]Indole	OC1=CC=C(CN2C3=C(CCN(C3)C(=O)C3=CC=C(O)C=C3)C3=CC=CC=C23)C=C1
INHA	DB08265	inhibin, alpha	experimental	2-(TOLUENE-4-SULFONYL)-2H-BENZO[D][1,2,3]DIAZABORININ-1-OL	CC1=CC=C(C=C1)S(=O)(=O)N1N=CC2=C(C=CC=C2)B1O
INHA	DB08605	inhibin, alpha	experimental	6-METHYL-2(PROPANE-1-SULFONYL)-2H-THIENO[3,2-D][1,2,3]DIAZABORININ-1-OL	CCCS(=O)(=O)N1N=CC2=C(C=C(C)S2)B1O
INPP1	DB01356	inositol polyphosphate-1-phosphatase	approved	Lithium	[Li+]
INPPL1	DB00877	inositol polyphosphate phosphatase-like 1	approved; investigational	Sirolimus	CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1O
INS	DB01776	insulin	experimental	M-Cresol	CC1=CC=CC(O)=C1
INS	DB08231	insulin	experimental	MYRISTIC ACID	CCCCCCCCCCCCCC(O)=O
INS	DB00121	insulin	approved; nutraceutical	Biotin	OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12
INS	DB00877	insulin	approved; investigational	Sirolimus	CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1O
INS	DB00122	insulin	approved; nutraceutical	Choline	C[N+](C)(C)CCO
IQGAP1	DB00125	IQ motif containing GTPase activating protein 1	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
IQGAP1	DB00435	IQ motif containing GTPase activating protein 1	approved	Nitric Oxide	[N]=O
ISYNA1	DB01907	inositol-3-phosphate synthase 1	experimental	Nicotinamide-Adenine-Dinucleotide	NC(=O)C1=CC=C[N+](=C1)[C@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@@H]1O
ITPA	DB01033	inosine triphosphatase (nucleoside triphosphate pyrophosphatase)	approved	Mercaptopurine	S=C1N=CNC2=C1NC=N2
ITPA	DB00563	inosine triphosphatase (nucleoside triphosphate pyrophosphatase)	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
ITPA	DB00993	inosine triphosphatase (nucleoside triphosphate pyrophosphatase)	approved	Azathioprine	CN1C=NC(=C1SC1=NC=NC2=C1NC=N2)[N+]([O-])=O
ITPA	DB00158	inosine triphosphatase (nucleoside triphosphate pyrophosphatase)	approved; nutraceutical	Folic Acid	NC1=NC(=O)C2=NC(CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)=CN=C2N1
ITPKA	DB01863	inositol-trisphosphate 3-kinase A	experimental	Inositol 1,3,4,5-Tetrakisphosphate	O[C@H]1[C@H](OP(O)(O)=O)[C@@H](O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@@H]1OP(O)(O)=O
ITPKA	DB03401	inositol-trisphosphate 3-kinase A	experimental	D-Myo-Inositol-1,4,5-Triphosphate	O[C@@H]1[C@@H](O)[C@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@H](O)[C@H]1OP(O)(O)=O
ITPKA	DB03431	inositol-trisphosphate 3-kinase A	experimental	Adenosine-5'-Diphosphate	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](CO[P@](O)(=O)OP(O)(O)=O)[C@H](O)[C@H]1O
ITPKA	DB04395	inositol-trisphosphate 3-kinase A	experimental	Phosphoaminophosphonic Acid-Adenylate Ester	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](CO[P@](O)(=O)O[P@@](O)(=O)NP(O)(O)=O)[C@H](O)[C@H]1O
IVD	DB03147	isovaleryl-CoA dehydrogenase	experimental	Flavin-Adenine Dinucleotide	CC1=CC2=C(C=C1C)N(C[C@H](O)[C@H](O)[C@H](O)CO[P@](O)(=O)O[P@@](O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC3=C1N=CN=C3N)C1=NC(=O)NC(=O)C1=N2
IVD	DB04036	isovaleryl-CoA dehydrogenase	experimental	Coenzyme a Persulfide	CC(C)(CO[P@](O)(=O)O[P@@](O)(=O)OC[C@@H]1O[C@H]([C@H](O)[C@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N)[C@@H](O)C(=O)NCCC(=O)NCCSS
IVD	DB00121	isovaleryl-CoA dehydrogenase	approved; nutraceutical	Biotin	OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12
IVD	DB00149	isovaleryl-CoA dehydrogenase	approved; nutraceutical	L-Leucine	CC(C)CC(N)C(O)=O
IYD	DB03374	iodotyrosine deiodinase	experimental	3,5-Diiodotyrosine	N[C@@H](CC1=CC(I)=C(O)C(I)=C1)C(O)=O
KCNJ11	DB00222	potassium inwardly-rectifying channel, subfamily J, member 11	approved	Glimepiride	CCC1=C(C)CN(C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC2CCC(C)CC2)C1=O
KCNJ11	DB00308	potassium inwardly-rectifying channel, subfamily J, member 11	approved	Ibutilide	CCCCCCCN(CC)CCCC(O)C1=CC=C(NS(C)(=O)=O)C=C1
KCNJ11	DB00661	potassium inwardly-rectifying channel, subfamily J, member 11	approved	Verapamil	COC1=C(OC)C=C(CCN(C)CCCC(C#N)(C(C)C)C2=CC(OC)=C(OC)C=C2)C=C1
KCNJ11	DB00922	potassium inwardly-rectifying channel, subfamily J, member 11	approved; investigational	Levosimendan	C[C@@H]1CC(=O)NN=C1C1=CC=C(NN=C(C#N)C#N)C=C1
KCNJ11	DB01016	potassium inwardly-rectifying channel, subfamily J, member 11	approved	Glyburide	COC1=C(C=C(Cl)C=C1)C(=O)NCCC1=CC=C(C=C1)S(=O)(=O)NC(=O)NC1CCCCC1
KCNJ11	DB01119	potassium inwardly-rectifying channel, subfamily J, member 11	approved	Diazoxide	CC1=NS(=O)(=O)C2=C(N1)C=CC(Cl)=C2
KCNJ11	DB01154	potassium inwardly-rectifying channel, subfamily J, member 11	approved	Thiamylal	CCCC(C)C1(CC=C)C(=O)NC(=S)NC1=O
KCNJ11	DB00912	potassium inwardly-rectifying channel, subfamily J, member 11	approved; investigational	Repaglinide	CCOC1=C(C=CC(CC(=O)N[C@@H](CC(C)C)C2=CC=CC=C2N2CCCCC2)=C1)C(O)=O
KCNJ11	DB00121	potassium inwardly-rectifying channel, subfamily J, member 11	approved; nutraceutical	Biotin	OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12
KCNJ11	DB01124	potassium inwardly-rectifying channel, subfamily J, member 11	approved	Tolbutamide	CCCCNC(=O)NS(=O)(=O)C1=CC=C(C)C=C1
KMO	DB00130	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	approved; nutraceutical; investigational	L-Glutamine	N[C@@H](CCC(N)=O)C(O)=O
KMO	DB00160	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	approved; nutraceutical	L-Alanine	C[C@H](N)C(O)=O
KMO	DB00150	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	approved; nutraceutical	L-Tryptophan	N[C@@H](CC1=CNC2=CC=CC=C12)C(O)=O
KYNU	DB00114	kynureninase	nutraceutical	Pyridoxal Phosphate	CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O
KYNU	DB00160	kynureninase	approved; nutraceutical	L-Alanine	C[C@H](N)C(O)=O
KYNU	DB07069	kynureninase	experimental	3-Hydroxyhippuric acid	OC(=O)CNC(=O)C1=CC(O)=CC=C1
KYNU	DB02343	kynureninase	experimental	3,6,9,12,15-Pentaoxaheptadecane	CCOCCOCCOCCOCCOCC
KYNU	DB00130	kynureninase	approved; nutraceutical; investigational	L-Glutamine	N[C@@H](CCC(N)=O)C(O)=O
KYNU	DB00150	kynureninase	approved; nutraceutical	L-Tryptophan	N[C@@H](CC1=CNC2=CC=CC=C12)C(O)=O
LCMT1	DB00149	leucine carboxyl methyltransferase 1	approved; nutraceutical	L-Leucine	CC(C)CC(N)C(O)=O
LCMT2	DB00149	leucine carboxyl methyltransferase 2	approved; nutraceutical	L-Leucine	CC(C)CC(N)C(O)=O
LCT	DB00126	lactase	approved; nutraceutical	Vitamin C	OC[C@H](O)[C@H]1OC(=O)C(O)=C1O
LCT	DB02376	lactase	experimental	D-Gluconhydroximo-1,5-Lactam	OC[C@H]1N\C(=N/O)[C@@H](O)[C@@H](O)[C@@H]1O
LCT	DB02471	lactase	experimental	Nojirimycine Tetrazole	OC[C@H]1[C@H](O)[C@@H](O)[C@H](O)C2=NN=NN12
LCT	DB02944	lactase	experimental	Alpha-D-Mannose	OC[C@@H]1O[C@H](O)[C@@H](O)[C@H](O)[C@H]1O
LCT	DB03389	lactase	experimental	alpha-D-Xylopyranose	O[C@@H]1CO[C@H](O)[C@H](O)[C@H]1O
LCT	DB04282	lactase	experimental	2-Deoxy-2fluoro-Glucose	OC[C@H]1O[C@@H](O)[C@H](F)[C@@H](O)[C@@H]1O
LCT	DB04564	lactase	experimental	Gluconolactone	OC[C@H]1OC(=O)[C@H](O)[C@@H](O)[C@@H]1O
LCT	DB04659	lactase	experimental	(1S,2S,3R,4S,5S)-2,3,4-TRIHYDROXY-5-(HYDROXYMETHYL)CYCLOHEXYL (1E)-2-PHENYL-N-(SULFOOXY)ETHANIMIDOTHIOATE	OC[C@H]1C[C@@H](S\C(=N/OS(O)(=O)=O)CC2=CC=CC=C2)[C@H](O)[C@@H](O)[C@@H]1O
LCT	DB04779	lactase	experimental	ETHYL (1E)-2-PHENYL-N-(SULFOOXY)ETHANIMIDOTHIOATE	CCS\C(CC1=CC=CC=C1)=N/OS(O)(=O)=O
LCT	DB08558	lactase	experimental	2-HYDROXYMETHYL-6-OCTYLSULFANYL-TETRAHYDRO-PYRAN-3,4,5-TRIOL	CCCCCCCCS[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O
LCT	DB04465	lactase	experimental	Lactose	OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O
LDHA	DB00157	lactate dehydrogenase A	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
LDHA	DB01907	lactate dehydrogenase A	experimental	Nicotinamide-Adenine-Dinucleotide	NC(=O)C1=CC=C[N+](=C1)[C@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@@H]1O
LDHA	DB02483	lactate dehydrogenase A	experimental	Etheno-Nad	O[C@H]1O[C@H](CO[P@](O)(=O)O[P@@](O)(=O)OC[C@@H]2O[C@H]([C@H](O)[C@H]2O)N2C=NC3=C2N=CN2C=CN=C32)[C@@H](O)[C@@H]1O
LDHA	DB02701	lactate dehydrogenase A	experimental	Nicotinamide	NC(=O)C1=CC=CN=C1
LDHA	DB03940	lactate dehydrogenase A	experimental	Oxamic Acid	NC(=O)C(O)=O
LDHA	DB00171	lactate dehydrogenase A	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
LDHA	DB00119	lactate dehydrogenase A	approved; nutraceutical	Pyruvic acid	CC(=O)C(O)=O
LDHAL6A	DB00157	lactate dehydrogenase A-like 6A	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
LDHAL6B	DB00157	lactate dehydrogenase A-like 6B	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
LDHB	DB00157	lactate dehydrogenase B	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
LDHB	DB01907	lactate dehydrogenase B	experimental	Nicotinamide-Adenine-Dinucleotide	NC(=O)C1=CC=C[N+](=C1)[C@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@@H]1O
LDHB	DB02401	lactate dehydrogenase B	experimental	4-Hydroxy-1,2,5-Oxadiazole-3-Carboxylic Acid	OC(=O)C1=NON=C1O
LDHB	DB03940	lactate dehydrogenase B	experimental	Oxamic Acid	NC(=O)C(O)=O
LDHC	DB00157	lactate dehydrogenase C	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
LDLR	DB00707	low density lipoprotein receptor	approved; investigational	Porfimer	CC(O)C1=C(C)/C2=C/C3=C(C(C)OC(C)C4=C(C)/C5=C/C6=C(C(C)O)C(C)=C(N6)\C=C6/N=C(/C=C7\N=C(\C=C\4/N\5)C(C)=C7CCC(O)=O)C(CCC(O)=O)=C6C)C(C)=C(N3)\C=C3/N=C(/C=C4\N=C(\C=C\1/N\2)C(C)=C4CCC(O)=O)C(CCC(O)=O)=C3C
LDLR	DB02944	low density lipoprotein receptor	experimental	Alpha-D-Mannose	OC[C@@H]1O[C@H](O)[C@@H](O)[C@H](O)[C@H]1O
LDLR	DB01095	low density lipoprotein receptor	approved	Fluvastatin	CC(C)N1C(\C=C\[C@H](O)C[C@H](O)CC(O)=O)=C(C2=CC=C(F)C=C2)C2=CC=CC=C12
LDLR	DB00335	low density lipoprotein receptor	approved	Atenolol	CC(C)NCC(O)COC1=CC=C(CC(N)=O)C=C1
LDLR	DB01029	low density lipoprotein receptor	approved; investigational	Irbesartan	CCCCC1=NC2(CCCC2)C(=O)N1CC1=CC=C(C=C1)C1=CC=CC=C1C1=NNN=N1
LDLR	DB01076	low density lipoprotein receptor	approved	Atorvastatin	CC(C)C1=C(C(=O)NC2=CC=CC=C2)C(=C(N1CC[C@@H](O)C[C@@H](O)CC(O)=O)C1=CC=C(F)C=C1)C1=CC=CC=C1
LDLR	DB00264	low density lipoprotein receptor	approved; investigational	Metoprolol	COCCC1=CC=C(OCC(O)CNC(C)C)C=C1
LEP	DB00734	leptin	approved; investigational	Risperidone	CC1=C(CCN2CCC(CC2)C2=NOC3=C2C=CC(F)=C3)C(=O)N2CCCCC2=N1
LEP	DB01041	leptin	approved; withdrawn; investigational	Thalidomide	O=C1N(C2CCC(=O)NC2=O)C(=O)C2=CC=CC=C12
LEP	DB00334	leptin	approved; investigational	Olanzapine	CN1CCN(CC1)C1=C2C=C(C)SC2=NC2=CC=CC=C2N1
LEP	DB00898	leptin	approved	Ethanol	CCO
LGMN	DB00136	legumain	approved; nutraceutical	Calcitriol	C[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2C(CCC[C@]12C)=CC=C1C[C@@H](O)C[C@H](O)C1=C
LIPC	DB00682	lipase, hepatic	approved	Warfarin	CC(=O)CC(C1=CC=CC=C1)C1=C(O)OC2=CC=CC=C2C1=O
LIPC	DB01095	lipase, hepatic	approved	Fluvastatin	CC(C)N1C(\C=C\[C@H](O)C[C@H](O)CC(O)=O)=C(C2=CC=C(F)C=C2)C2=CC=CC=C12
LIPC	DB00375	lipase, hepatic	approved	Colestipol	ClCC1CO1.NCCNCCNCCNCCN
LIPC	DB00264	lipase, hepatic	approved; investigational	Metoprolol	COCCC1=CC=C(OCC(O)CNC(C)C)C=C1
LIPF	DB01083	lipase, gastric	approved; investigational	Orlistat	CCCCCCCCCCC[C@@H](C[C@@H]1OC(=O)[C@H]1CCCCCC)OC(=O)[C@H](CC(C)C)NC=O
LIPF	DB02457	lipase, gastric	experimental	Undecyl-Phosphinic Acid Butyl Ester	CCCCCCCCCCCP(=O)OCCCC
LPA	DB00513	lipoprotein, Lp(a)	approved; investigational	Aminocaproic Acid	NCCCCCC(O)=O
LPIN1	DB00412	lipin 1	approved; investigational	Rosiglitazone	CN(CCOC1=CC=C(CC2SC(=O)NC2=O)C=C1)C1=CC=CC=N1
LPL	DB00741	lipoprotein lipase	approved	Hydrocortisone	C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
LPL	DB01132	lipoprotein lipase	approved; investigational	Pioglitazone	CCC1=CN=C(CCOC2=CC=C(CC3SC(=O)NC3=O)C=C2)C=C1
LPL	DB00412	lipoprotein lipase	approved; investigational	Rosiglitazone	CN(CCOC1=CC=C(CC2SC(=O)NC2=O)C=C1)C1=CC=CC=N1
LPL	DB00197	lipoprotein lipase	withdrawn	Troglitazone	CC1=C(C)C2=C(CCC(C)(COC3=CC=C(CC4SC(=O)NC4=O)C=C3)O2)C(C)=C1O
LPL	DB01095	lipoprotein lipase	approved	Fluvastatin	CC(C)N1C(\C=C\[C@H](O)C[C@H](O)CC(O)=O)=C(C2=CC=C(F)C=C2)C2=CC=CC=C12
LPL	DB00363	lipoprotein lipase	approved	Clozapine	CN1CCN(CC1)C1=NC2=CC(Cl)=CC=C2NC2=CC=CC=C12
LPL	DB00334	lipoprotein lipase	approved; investigational	Olanzapine	CN1CCN(CC1)C1=C2C=C(C)SC2=NC2=CC=CC=C2N1
LPL	DB01039	lipoprotein lipase	approved	Fenofibrate	CC(C)OC(=O)C(C)(C)OC1=CC=C(C=C1)C(=O)C1=CC=C(Cl)C=C1
LPL	DB00264	lipoprotein lipase	approved; investigational	Metoprolol	COCCC1=CC=C(OCC(O)CNC(C)C)C=C1
LRAT	DB00162	lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)	approved; nutraceutical	Vitamin A	CC(=CCO)C=CC=C(C)C=CC1=C(C)CCCC1(C)C
LRP2	DB00798	low density lipoprotein receptor-related protein 2	approved	Gentamicin	CNC(C)C1CCC(N)C(OC2C(N)CC(N)C(OC3OCC(C)(O)C(NC)C3O)C2O)O1
LRP2	DB00136	low density lipoprotein receptor-related protein 2	approved; nutraceutical	Calcitriol	C[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2C(CCC[C@]12C)=CC=C1C[C@@H](O)C[C@H](O)C1=C
LRP2	DB00515	low density lipoprotein receptor-related protein 2	approved	Cisplatin	N[Pt](N)(Cl)Cl
LSM2	DB00564	LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)	approved; investigational	Carbamazepine	NC(=O)N1C2=CC=CC=C2C=CC2=CC=CC=C12
LTA4H	DB02062	leukotriene A4 hydrolase	experimental	N-[3-[(1-Aminoethyl)(Hydroxy)Phosphoryl]-2-(1,1'-Biphenyl-4-Ylmethyl)Propanoyl]Alanine	C[C@H](N)[P@](O)(=O)C[C@@H](CC1=CC=C(C=C1)C1=CC=CC=C1)C(=O)N[C@@H](C)C(O)=O
LTA4H	DB02352	leukotriene A4 hydrolase	experimental	3-(Benzyloxy)Pyridin-2-Amine	NC1=NC=CC=C1OCC1=CC=CC=C1
LTA4H	DB03424	leukotriene A4 hydrolase	experimental	Bestatin	CC(C)C[C@@H](NC(=O)[C@@H](O)[C@H](N)CC1=CC=CC=C1)C(O)=O
LTA4H	DB06828	leukotriene A4 hydrolase	experimental	5-[2-(1H-pyrrol-1-yl)ethoxy]-1H-indole	C(CN1C=CC=C1)OC1=CC2=C(NC=C2)C=C1
LTA4H	DB06851	leukotriene A4 hydrolase	experimental	N-(pyridin-3-ylmethyl)aniline	C(NC1=CC=CC=C1)C1=CC=CN=C1
LTA4H	DB06917	leukotriene A4 hydrolase	experimental	(4-fluorophenyl)(pyridin-4-yl)methanone	FC1=CC=C(C=C1)C(=O)C1=CC=NC=C1
LTA4H	DB07094	leukotriene A4 hydrolase	experimental	1-(2,2'-bithiophen-5-yl)methanamine	NCC1=CC=C(S1)C1=CC=CS1
LTA4H	DB07099	leukotriene A4 hydrolase	experimental	N-[4-(benzyloxy)phenyl]glycinamide	NCC(=O)NC1=CC=C(OCC2=CC=CC=C2)C=C1
LTA4H	DB07102	leukotriene A4 hydrolase	experimental	(2S)-2-amino-5-oxo-5-[(4-phenylmethoxyphenyl)amino]pentanoic acid	N[C@@H](CCC(=O)NC1=CC=C(OCC2=CC=CC=C2)C=C1)C(O)=O
LTA4H	DB07104	leukotriene A4 hydrolase	experimental	4-amino-N-[4-(benzyloxy)phenyl]butanamide	NCCCC(=O)NC1=CC=C(OCC2=CC=CC=C2)C=C1
LTA4H	DB07196	leukotriene A4 hydrolase	experimental	N-methyl-1-(2-thiophen-2-ylphenyl)methanamine	CNCC1=CC=CC=C1C1=CC=CS1
LTA4H	DB07237	leukotriene A4 hydrolase	experimental	{4-[(2R)-pyrrolidin-2-ylmethoxy]phenyl}(4-thiophen-3-ylphenyl)methanone	O=C(C1=CC=C(OC[C@H]2CCCN2)C=C1)C1=CC=C(C=C1)C1=CSC=C1
LTA4H	DB07258	leukotriene A4 hydrolase	experimental	(R)-pyridin-4-yl[4-(2-pyrrolidin-1-ylethoxy)phenyl]methanol	O[C@@H](C1=CC=NC=C1)C1=CC=C(OCCN2CCCC2)C=C1
LTA4H	DB07259	leukotriene A4 hydrolase	experimental	1-(4-thiophen-2-ylphenyl)methanamine	NCC1=CC=C(C=C1)C1=CC=CS1
LTA4H	DB07260	leukotriene A4 hydrolase	experimental	N-benzyl-4-[(2R)-pyrrolidin-2-ylmethoxy]aniline	C(NC1=CC=C(OC[C@H]2CCCN2)C=C1)C1=CC=CC=C1
LTA4H	DB07292	leukotriene A4 hydrolase	experimental	4-(2-amino-1,3-thiazol-4-yl)phenol	NC1=NC(=CS1)C1=CC=C(O)C=C1
LTA4H	DB08040	leukotriene A4 hydrolase	experimental	N-[(2R)-2-benzyl-4-(hydroxyamino)-4-oxobutanoyl]-L-alanine	C[C@H](NC(=O)[C@@H](CC(=O)NO)CC1=CC=CC=C1)C(O)=O
LTA4H	DB08466	leukotriene A4 hydrolase	experimental	5-[2-(4-hydroxyphenyl)ethyl]benzene-1,3-diol	OC1=CC=C(CCC2=CC(O)=CC(O)=C2)C=C1
LTA4H	DB00143	leukotriene A4 hydrolase	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
LTA4H	DB00145	leukotriene A4 hydrolase	approved; nutraceutical	Glycine	NCC(O)=O
LTA4H	DB00471	leukotriene A4 hydrolase	approved	Montelukast	OC(=O)CC1(CC1)CS[C@H](CCC1=CC=CC=C1C(O)(C)C)C1=CC=CC(\C=C\C2=NC3=C(C=CC(Cl)=C3)C=C2)=C1
LTC4S	DB00143	leukotriene C4 synthase	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
LTC4S	DB00145	leukotriene C4 synthase	approved; nutraceutical	Glycine	NCC(O)=O
LTC4S	DB00945	leukotriene C4 synthase	approved	Acetylsalicylic acid	CC(=O)OC1=CC=CC=C1C(O)=O
LTC4S	DB00471	leukotriene C4 synthase	approved	Montelukast	OC(=O)CC1(CC1)CS[C@H](CCC1=CC=CC=C1C(O)(C)C)C1=CC=CC(\C=C\C2=NC3=C(C=CC(Cl)=C3)C=C2)=C1
LYPLA1	DB00360	lysophospholipase I	approved; investigational	Tetrahydrobiopterin	CC(O)C(O)C1CNC2=C(N1)C(=O)N=C(N)N2
MAN1B1	DB01955	mannosidase, alpha, class 1B, member 1	experimental	1,4-Butanediol	OCCCCO
MAN1B1	DB02422	mannosidase, alpha, class 1B, member 1	experimental	Methyl-2-S-(Alpha-D-Mannopyranosyl)-2-Thio-Alpha-D-Mannopyranoside	CO[C@H]1O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]1S[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O
MAN1B1	DB02742	mannosidase, alpha, class 1B, member 1	experimental	Kifunensine	OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@@H]2NC(=O)C(=O)N12
MAN1B1	DB02944	mannosidase, alpha, class 1B, member 1	experimental	Alpha-D-Mannose	OC[C@@H]1O[C@H](O)[C@@H](O)[C@H](O)[C@H]1O
MAN1B1	DB03206	mannosidase, alpha, class 1B, member 1	experimental	1-Deoxynojirimycin	OC[C@@H]1NC[C@@H](O)[C@H](O)[C@H]1O
MAN1B1	DB00694	mannosidase, alpha, class 1B, member 1	approved	Daunorubicin	COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3O[C@H]3C[C@H](N)[C@H](O)[C@H](C)O3)C(C)=O)C(O)=C1C2=O
MAN2A1	DB02034	mannosidase, alpha, class 2A, member 1	experimental	Swainsonine	O[C@@H]1CN2CCC[C@H](O)[C@H]2[C@@H]1O
MAN2A1	DB02318	mannosidase, alpha, class 2A, member 1	experimental	2-Deoxy-2-Fluoro-Alpha-D-Mannosyl Fluoride	OC[C@H]1O[C@@H](F)[C@H](F)[C@@H](O)[C@@H]1O
MAN2A1	DB02492	mannosidase, alpha, class 2A, member 1	experimental	Ghavamiol	OC[C@H](OS([O-])([O-])[O-])[C@@H](O)CN1C[C@@H](O)[C@H](O)[C@H]1CO
MAN2A1	DB02742	mannosidase, alpha, class 2A, member 1	experimental	Kifunensine	OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@@H]2NC(=O)C(=O)N12
MAN2A1	DB03008	mannosidase, alpha, class 2A, member 1	experimental	5-Fluoro-Beta-L-Gulosyl Fluoride	OC[C@@]1(F)O[C@H](F)[C@@H](O)[C@H](O)[C@H]1O
MAN2A1	DB03414	mannosidase, alpha, class 2A, member 1	experimental	5-Thio-a/B-D-Mannopyranosylamine	N[C@@H]1S[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O
MAN2A1	DB03955	mannosidase, alpha, class 2A, member 1	experimental	1,5-Dideoxy-1,5-Imino-D-Mannitol	OC[C@@H]1NC[C@@H](O)[C@H](O)[C@H]1O
MAN2A1	DB06984	mannosidase, alpha, class 2A, member 1	experimental	(1R,2R,3R,4S,5R)-4-(BENZYLAMINO)-5-(METHYLTHIO)CYCLOPENTANE-1,2,3-TRIOL	CS[C@H]1[C@H](O)[C@H](O)[C@H](O)[C@@H]1NCC1=CC=CC=C1
MAN2A1	DB08321	mannosidase, alpha, class 2A, member 1	experimental	(1S,2S,3R,6R)-4-(hydroxymethyl)-6-(octylamino)cyclohex-4-ene-1,2,3-triol	CCCCCCCCN[C@@H]1C=C(CO)[C@@H](O)[C@H](O)[C@H]1O
MAOA	DB00191	monoamine oxidase A	illicit; approved	Phentermine	CC(C)(N)CC1=CC=CC=C1
MAOA	DB00752	monoamine oxidase A	approved	Tranylcypromine	N[C@@H]1CC1C1=CC=CC=C1
MAOA	DB00780	monoamine oxidase A	approved	Phenelzine	NNCCC1=CC=CC=C1
MAOA	DB00805	monoamine oxidase A	approved	Minaprine	CC1=CC(=NN=C1NCCN1CCOCC1)C1=CC=CC=C1
MAOA	DB00909	monoamine oxidase A	approved; investigational	Zonisamide	NS(=O)(=O)CC1=NOC2=CC=CC=C12
MAOA	DB01037	monoamine oxidase A	approved; investigational	Selegiline	C[C@H](CC1=CC=CC=C1)N(C)CC#C
MAOA	DB01171	monoamine oxidase A	approved	Moclobemide	ClC1=CC=C(C=C1)C(=O)NCCN1CCOCC1
MAOA	DB01247	monoamine oxidase A	approved	Isocarboxazid	CC1=CC(=NO1)C(=O)NNCC1=CC=CC=C1
MAOA	DB01442	monoamine oxidase A	illicit; experimental	MMDA	COC1=CC(CC(C)N)=CC2=C1OCO2
MAOA	DB01472	monoamine oxidase A	illicit; experimental	4-Methoxyamphetamine	COC1=CC=C(CC(C)N)C=C1
MAOA	DB01577	monoamine oxidase A	illicit; approved	Methamphetamine	CN[C@@H](C)CC1=CC=CC=C1
MAOA	DB01626	monoamine oxidase A	approved	Pargyline	CN(CC#C)CC1=CC=CC=C1
MAOA	DB03147	monoamine oxidase A	experimental	Flavin-Adenine Dinucleotide	CC1=CC2=C(C=C1C)N(C[C@H](O)[C@H](O)[C@H](O)CO[P@](O)(=O)O[P@@](O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC3=C1N=CN=C3N)C1=NC(=O)NC(=O)C1=N2
MAOA	DB04017	monoamine oxidase A	experimental	N-Methyl-N-Propargyl-3-(2,4-Dichlorophenoxy)Propylamine	CN(CCCOC1=CC=C(Cl)C=C1Cl)CC#C
MAOA	DB04820	monoamine oxidase A	withdrawn	Nialamide	O=C(CCNNC(=O)C1=CC=NC=C1)NCC1=CC=CC=C1
MAOA	DB04821	monoamine oxidase A	withdrawn	Nomifensine	CN1CC(C2=CC=CC=C2)C2=C(C1)C(N)=CC=C2
MAOA	DB04832	monoamine oxidase A	withdrawn	Zimelidine	CN(C)CC=C(C1=CC=C(Br)C=C1)C1=CN=CC=C1
MAOA	DB07641	monoamine oxidase A	experimental	DECYL(DIMETHYL)PHOSPHINE OXIDE	CCCCCCCCCCP(C)(C)=O
MAOA	DB07919	monoamine oxidase A	experimental	7-METHOXY-1-METHYL-9H-BETA-CARBOLINE	COC1=CC=C2C(NC3=C2C=CN=C3C)=C1
MAOA	DB00215	monoamine oxidase A	approved	Citalopram	CN(C)CCCC1(OCC2=C1C=CC(=C2)C#N)C1=CC=C(F)C=C1
MAOA	DB00176	monoamine oxidase A	approved; investigational	Fluvoxamine	COCCCCC(=NOCCN)C1=CC=C(C=C1)C(F)(F)F
MAOA	DB00715	monoamine oxidase A	approved; investigational	Paroxetine	FC1=CC=C(C=C1)[C@@H]1CCNC[C@H]1COC1=CC2=C(OCO2)C=C1
MAOA	DB01104	monoamine oxidase A	approved	Sertraline	CN[C@H]1CC[C@@H](C2=CC(Cl)=C(Cl)C=C2)C2=CC=CC=C12
MAOA	DB00184	monoamine oxidase A	approved	Nicotine	CN1CCCC1C1=CN=CC=C1
MAOA	DB00988	monoamine oxidase A	approved	Dopamine	NCCC1=CC(O)=C(O)C=C1
MAOA	DB00368	monoamine oxidase A	approved	Norepinephrine	NC[C@H](O)C1=CC(O)=C(O)C=C1
MAOA	DB00126	monoamine oxidase A	approved; nutraceutical	Vitamin C	OC[C@H](O)[C@H]1OC(=O)C(O)=C1O
MAOA	DB00472	monoamine oxidase A	approved	Fluoxetine	CNCCC(OC1=CC=C(C=C1)C(F)(F)F)C1=CC=CC=C1
MAOA	DB00734	monoamine oxidase A	approved; investigational	Risperidone	CC1=C(CCN2CCC(CC2)C2=NOC3=C2C=CC(F)=C3)C(=O)N2CCCCC2=N1
MAOB	DB00191	monoamine oxidase B	illicit; approved	Phentermine	CC(C)(N)CC1=CC=CC=C1
MAOB	DB00752	monoamine oxidase B	approved	Tranylcypromine	N[C@@H]1CC1C1=CC=CC=C1
MAOB	DB00780	monoamine oxidase B	approved	Phenelzine	NNCCC1=CC=CC=C1
MAOB	DB00909	monoamine oxidase B	approved; investigational	Zonisamide	NS(=O)(=O)CC1=NOC2=CC=CC=C12
MAOB	DB01037	monoamine oxidase B	approved; investigational	Selegiline	C[C@H](CC1=CC=CC=C1)N(C)CC#C
MAOB	DB01247	monoamine oxidase B	approved	Isocarboxazid	CC1=CC(=NO1)C(=O)NNCC1=CC=CC=C1
MAOB	DB01367	monoamine oxidase B	approved	Rasagiline	C#CCN[C@@H]1CCC2=CC=CC=C12
MAOB	DB01442	monoamine oxidase B	illicit; experimental	MMDA	COC1=CC(CC(C)N)=CC2=C1OCO2
MAOB	DB01472	monoamine oxidase B	illicit; experimental	4-Methoxyamphetamine	COC1=CC=C(CC(C)N)C=C1
MAOB	DB01577	monoamine oxidase B	illicit; approved	Methamphetamine	CN[C@@H](C)CC1=CC=CC=C1
MAOB	DB01626	monoamine oxidase B	approved	Pargyline	CN(CC#C)CC1=CC=CC=C1
MAOB	DB02095	monoamine oxidase B	experimental	Isatin	O=C1NC2=CC=CC=C2C1=O
MAOB	DB02211	monoamine oxidase B	experimental	N-Methyl-N-Propargyl-1(R)-Aminoindan	CN(CC#C)[C@@H]1CCC2=C1C=CC=C2
MAOB	DB02509	monoamine oxidase B	experimental	Farnesol	CC(C)=CCC\C(C)=C/CC\C(C)=C/CO
MAOB	DB02643	monoamine oxidase B	experimental	N-Dodecyl-N,N-Dimethyl-3-Ammonio-1-Propanesulfonate	CCCCCCCCCCCC[N+](C)(C)CCCS(O)(=O)=O
MAOB	DB02939	monoamine oxidase B	experimental	[(1e)-4-Phenylbut-1-Enyl]Benzene	C(CC1=CC=CC=C1)\C=C\C1=CC=CC=C1
MAOB	DB03147	monoamine oxidase B	experimental	Flavin-Adenine Dinucleotide	CC1=CC2=C(C=C1C)N(C[C@H](O)[C@H](O)[C@H](O)CO[P@](O)(=O)O[P@@](O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC3=C1N=CN=C3N)C1=NC(=O)NC(=O)C1=N2
MAOB	DB03894	monoamine oxidase B	experimental	N-Propargyl-1(S)-Aminoindan	C#CCN[C@H]1CCC2=C1C=CC=C2
MAOB	DB04147	monoamine oxidase B	experimental	Lauryl Dimethylamine-N-Oxide	CCCCCCCCCCCC[N+](C)(C)[O-]
MAOB	DB04307	monoamine oxidase B	experimental	5-Hydroxy-N-Propargyl-1(R)-Aminoindan	OC1=CC=C2CC[C@@H](NCC#C)C2=C1
MAOB	DB04677	monoamine oxidase B	experimental	N-METHYL-N-[(1R)-1-METHYL-2-PHENYLETHYL]PROP-2-EN-1-AMINE	C[C@H](CC1=CC=CC=C1)N(C)CC=C
MAOB	DB04820	monoamine oxidase B	withdrawn	Nialamide	O=C(CCNNC(=O)C1=CC=NC=C1)NCC1=CC=CC=C1
MAOB	DB04821	monoamine oxidase B	withdrawn	Nomifensine	CN1CC(C2=CC=CC=C2)C2=C(C1)C(N)=CC=C2
MAOB	DB04832	monoamine oxidase B	withdrawn	Zimelidine	CN(C)CC=C(C1=CC=C(Br)C=C1)C1=CN=CC=C1
MAOB	DB07512	monoamine oxidase B	experimental	7-[(3-CHLOROBENZYL)OXY]-2-OXO-2H-CHROMENE-4-CARBALDEHYDE	ClC1=CC=CC(COC2=CC=C3C(OC(=O)C=C3C=O)=C2)=C1
MAOB	DB07513	monoamine oxidase B	experimental	7-[(3-CHLOROBENZYL)OXY]-4-[(METHYLAMINO)METHYL]-2H-CHROMEN-2-ONE	CNCC1=CC(=O)OC2=C1C=CC(OCC1=CC=CC(Cl)=C1)=C2
MAOB	DB08082	monoamine oxidase B	experimental	N-(2-AMINOETHYL)-P-CHLOROBENZAMIDE	OCCNC(=O)C1=CC=C(Cl)C=C1
MAOB	DB08176	monoamine oxidase B	experimental	(1Z)-4-(4-FLUOROPHENYL)-2-METHYLIDENEBUTAN-1-IMINE	FC1=CC=C(CCC(=C)C=N)C=C1
MAOB	DB08480	monoamine oxidase B	experimental	4-HYDROXY-N-PROPARGYL-1(R)-AMINOINDAN	OC1=CC=CC2=C1CC[C@H]2\N=C\C=C
MAOB	DB08516	monoamine oxidase B	experimental	(S)-(+)-2-[4-(FLUOROBENZYLOXY-BENZYLAMINO)PROPIONAMIDE]	C[C@H](\N=C\C1=CC=C(OCC2=CC(F)=CC=C2)C=C1)C(N)=O
MAOB	DB00988	monoamine oxidase B	approved	Dopamine	NCCC1=CC(O)=C(O)C=C1
MAOB	DB00368	monoamine oxidase B	approved	Norepinephrine	NC[C@H](O)C1=CC(O)=C(O)C=C1
MAOB	DB01394	monoamine oxidase B	approved	Colchicine	COC1=C(OC)C(OC)=C2C(CC[C@H](NC(C)=O)C3=CC(=O)C(OC)=CC=C23)=C1
MAOB	DB00864	monoamine oxidase B	approved; investigational	Tacrolimus	CO[C@@H]1C[C@@H](CC[C@H]1O)\C=C(/C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H]([C@H](C[C@H]2C)OC)[C@H](C[C@@H](C)C\C(C)=C\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]1C)OC
MAOB	DB00370	monoamine oxidase B	approved	Mirtazapine	CN1CCN2C(C1)C1=CC=CC=C1CC1=C2N=CC=C1
MAOB	DB00715	monoamine oxidase B	approved; investigational	Paroxetine	FC1=CC=C(C=C1)[C@@H]1CCNC[C@H]1COC1=CC2=C(OCO2)C=C1
MAOB	DB00215	monoamine oxidase B	approved	Citalopram	CN(C)CCCC1(OCC2=C1C=CC(=C2)C#N)C1=CC=C(F)C=C1
MAOB	DB00734	monoamine oxidase B	approved; investigational	Risperidone	CC1=C(CCN2CCC(CC2)C2=NOC3=C2C=CC(F)=C3)C(=O)N2CCCCC2=N1
MAPK11	DB01234	mitogen-activated protein kinase 11	approved; investigational	Dexamethasone	C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
MAPK11	DB00398	mitogen-activated protein kinase 11	approved; investigational	Sorafenib	CNC(=O)C1=NC=CC(OC2=CC=C(NC(=O)NC3=CC(=C(Cl)C=C3)C(F)(F)F)C=C2)=C1
MAPK11	DB00435	mitogen-activated protein kinase 11	approved	Nitric Oxide	[N]=O
MAPK11	DB00125	mitogen-activated protein kinase 11	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
MAPK14	DB01761	mitogen-activated protein kinase 14	experimental	4-[5-[2-(1-Phenyl-Ethylamino)-Pyrimidin-4-Yl]-1-Methyl-4-(3-Trifluoromethylphenyl)-1h-Imidazol-2-Yl]-Piperidine	C[C@H](NC1=NC=CC(=N1)C1=C(N=C(C2CCNCC2)N1C)C1=CC(=CC=C1)C(F)(F)F)C1=CC=CC=C1
MAPK14	DB01807	mitogen-activated protein kinase 14	experimental	N-[(3z)-5-Tert-Butyl-2-Phenyl-1,2-Dihydro-3h-Pyrazol-3-Ylidene]-N'-(4-Chlorophenyl)Urea	CC(C)(C)C1=C\C(=N/C(=O)NC2=CC=C(Cl)C=C2)N(N1)C1=CC=CC=C1
MAPK14	DB01948	mitogen-activated protein kinase 14	experimental	1-(2,6-Dichlorophenyl)-5-(2,4-Difluorophenyl)-7-Piperidin-4-Yl-3,4-Dihydroquinolin-2(1h)-One	FC1=CC=C(C(F)=C1)C1=CC(=CC2=C1CCC(=O)N2C1=C(Cl)C=CC=C1Cl)C1CCNCC1
MAPK14	DB01953	mitogen-activated protein kinase 14	experimental	Inhibitor of P38 Kinase	C(CC1=CC=NC=C1)C1=CNC2=CC=CC=C12
MAPK14	DB01988	mitogen-activated protein kinase 14	experimental	6((S)-3-Benzylpiperazin-1-Yl)-3-(Naphthalen-2-Yl)-4-(Pyridin-4-Yl)Pyrazine	C([C@H]1CN(CCN1)C1=NN=C(C2=CC3=CC=CC=C3C=C2)C(=C1)C1=CC=NC=C1)C1=CC=CC=C1
MAPK14	DB02195	mitogen-activated protein kinase 14	experimental	3-(4-Fluorophenyl)-1-Hydroxy-2-(Pyridin-4-Yl)-1h-Pyrrolo[3,2-B]Pyridine	ON1C2=CC=CN=C2C(=C1C1=CC=NC=C1)C1=CC=C(F)C=C1
MAPK14	DB02277	mitogen-activated protein kinase 14	experimental	1-(5-Tert-Butyl-2-Methyl-2h-Pyrazol-3-Yl)-3-(4-Chloro-Phenyl)-Urea	CN1N=C(C=C1NC(=O)NC1=CC=C(Cl)C=C1)C(C)(C)C
MAPK14	DB02352	mitogen-activated protein kinase 14	experimental	3-(Benzyloxy)Pyridin-2-Amine	NC1=NC=CC=C1OCC1=CC=CC=C1
MAPK14	DB02873	mitogen-activated protein kinase 14	experimental	1-(2,6-Dichlorophenyl)-5-(2,4-Difluorophenyl)-7-Piperazin-1-Yl-3,4-Dihydroquinazolin-2(1h)-One	FC1=CC=C(C(F)=C1)C1=C2CNC(=O)N(C2=CC(=C1)N1CCNCC1)C1=C(Cl)C=CC=C1Cl
MAPK14	DB02984	mitogen-activated protein kinase 14	experimental	4-[3-Methylsulfanylanilino]-6,7-Dimethoxyquinazoline	COC1=CC2=NC=NC(NC3=CC(SC)=CC=C3)=C2C=C1OC
MAPK14	DB03044	mitogen-activated protein kinase 14	experimental	1-(5-Tert-Butyl-2-P-Tolyl-2h-Pyrazol-3-Yl)-3-[4-(2-Morpholin-4-Yl-Ethoxy)-Naphthalen-1-Yl]-Urea	CC1=CC=C(C=C1)N1N=C(C=C1NC(=O)NC1=CC=C(OCCN2CCOCC2)C2=C1C=CC=C2)C(C)(C)C
MAPK14	DB03110	mitogen-activated protein kinase 14	experimental	2-Chlorophenol	OC1=CC=CC=C1Cl
MAPK14	DB03980	mitogen-activated protein kinase 14	experimental	4-(Fluorophenyl)-1-Cyclopropylmethyl-5-(2-Amino-4-Pyrimidinyl)Imidazole	NC1=NC(=CC=N1)C1=C(N=CN1CC1CC1)C1=CC=C(F)C=C1
MAPK14	DB04338	mitogen-activated protein kinase 14	experimental	SB220025	NC1=NC=CC(=N1)C1=C(N=CN1C1CCNCC1)C1=CC=C(F)C=C1
MAPK14	DB04632	mitogen-activated protein kinase 14	experimental	4-(2-HYDROXYBENZYLAMINO)-N-(3-(4-FLUOROPHENOXY)PHENYL)PIPERIDINE-1-SULFONAMIDE	OC1=C(CNC2CCN(CC2)S(=O)(=O)NC2=CC(OC3=CC=C(F)C=C3)=CC=C2)C=CC=C1
MAPK14	DB04797	mitogen-activated protein kinase 14	experimental	Triazolopyridine	CC(C)C1=NN=C2C=CC(=CN12)C1=C(N=CO1)C1=CC=C(F)C=C1
MAPK14	DB06882	mitogen-activated protein kinase 14	experimental	1-[1-(3-aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl]-3-naphthalen-1-ylurea	CC(C)(C)C1=NN(C(NC(=O)NC2=C3C=CC=CC3=CC=C2)=C1)C1=CC=CC(N)=C1
MAPK14	DB06940	mitogen-activated protein kinase 14	experimental	N-ethyl-4-{[5-(methoxycarbamoyl)-2-methylphenyl]amino}-5-methylpyrrolo[2,1-f][1,2,4]triazine-6-carboxamide	CCNC(=O)C1=CN2N=CN=C(NC3=CC(=CC=C3C)C(=O)NOC)C2=C1C
MAPK14	DB06991	mitogen-activated protein kinase 14	experimental	N-[2-methyl-5-(methylcarbamoyl)phenyl]-2-{[(1R)-1-methylpropyl]amino}-1,3-thiazole-5-carboxamide	CC[C@@H](C)NC1=NC=C(S1)C(=O)NC1=C(C)C=CC(=C1)C(=O)NC
MAPK14	DB07138	mitogen-activated protein kinase 14	experimental	5-(2,6-dichlorophenyl)-2-[(2,4-difluorophenyl)sulfanyl]-6H-pyrimido[1,6-b]pyridazin-6-one	FC1=CC(F)=C(SC2=NN3C=NC(=O)C(=C3C=C2)C2=C(Cl)C=CC=C2Cl)C=C1
MAPK14	DB07307	mitogen-activated protein kinase 14	experimental	N-cyclopropyl-4-methyl-3-[1-(2-methylphenyl)phthalazin-6-yl]benzamide	CC1=CC=CC=C1C1=NN=CC2=C1C=CC(=C2)C1=C(C)C=CC(=C1)C(=O)NC1CC1
MAPK14	DB07459	mitogen-activated protein kinase 14	experimental	4-PHENOXY-N-(PYRIDIN-2-YLMETHYL)BENZAMIDE	O=C(NCC1=NC=CC=C1)C1=CC=C(OC2=CC=CC=C2)C=C1
MAPK14	DB07607	mitogen-activated protein kinase 14	experimental	4-[5-(3-IODO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-1H-IMIDAZOL-4-YL]-PYRIDINE	C[S@@](=O)C1=CC=C(C=C1)C1=NC(=C(N1)C1=CC(I)=CC=C1)C1=CC=NC=C1
MAPK14	DB07811	mitogen-activated protein kinase 14	experimental	N-cyclopropyl-2',6-dimethyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-3-carboxamide	CC1=NN=C(O1)C1=CC=C(C(C)=C1)C1=CC(=CC=C1C)C(=O)NC1CC1
MAPK14	DB07829	mitogen-activated protein kinase 14	experimental	4-[3-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL]PYRIDINE	FC1=CC=C(C=C1)C1=NNC=C1C1=CC=NC=C1
MAPK14	DB07832	mitogen-activated protein kinase 14	experimental	4-{4-[(5-hydroxy-2-methylphenyl)amino]quinolin-7-yl}-1,3-thiazole-2-carbaldehyde	CC1=C(NC2=CC=NC3=CC(=CC=C23)C2=CSC(C=O)=N2)C=C(O)C=C1
MAPK14	DB07833	mitogen-activated protein kinase 14	experimental	N-(3-cyanophenyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)-4-biphenylcarboxamide	CC1=NN=C(O1)C1=CC=C(C)C(=C1)C1=CC=C(C=C1)C(=O)NC1=CC(=CC=C1)C#N
MAPK14	DB07834	mitogen-activated protein kinase 14	experimental	N-(cyclopropylmethyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-4-carboxamide	CC1=NN=C(O1)C1=CC=C(C)C(=C1)C1=CC=C(C=C1)C(=O)NCC1CC1
MAPK14	DB07835	mitogen-activated protein kinase 14	experimental	N~3~-cyclopropyl-N~4~'-(cyclopropylmethyl)-6-methylbiphenyl-3,4'-dicarboxamide	CC1=CC=C(C=C1C1=CC=C(C=C1)C(=O)NCC1CC1)C(=O)NC1CC1
MAPK14	DB07941	mitogen-activated protein kinase 14	experimental	3-{3-bromo-4-[(2,4-difluorobenzyl)oxy]-6-methyl-2-oxopyridin-1(2H)-yl}-N,4-dimethylbenzamide	CNC(=O)C1=CC=C(C)C(=C1)N1C(C)=CC(OCC2=C(F)C=C(F)C=C2)=C(Br)C1=O
MAPK14	DB07942	mitogen-activated protein kinase 14	experimental	2-fluoro-4-[4-(4-fluorophenyl)-1H-pyrazol-3-yl]pyridine	FC1=CC=C(C=C1)C1=CNN=C1C1=CC(F)=NC=C1
MAPK14	DB07943	mitogen-activated protein kinase 14	experimental	2-{4-[5-(4-chlorophenyl)-4-pyrimidin-4-yl-1H-pyrazol-3-yl]piperidin-1-yl}-2-oxoethanol	OCC(=O)N1CCC(CC1)C1=NNC(=C1C1=NC=NC=C1)C1=CC=C(Cl)C=C1
MAPK14	DB08064	mitogen-activated protein kinase 14	experimental	N-(3-TERT-BUTYL-1H-PYRAZOL-5-YL)-N'-{4-CHLORO-3-[(PYRIDIN-3-YLOXY)METHYL]PHENYL}UREA	CC(C)(C)C1=NNC(NC(=O)NC2=CC=C(Cl)C(COC3=CC=CN=C3)=C2)=C1
MAPK14	DB08068	mitogen-activated protein kinase 14	experimental	N-[4-CHLORO-3-(PYRIDIN-3-YLOXYMETHYL)-PHENYL]-3-FLUORO-	F[C@@H]1C[C@H](CC(=C1)C(=O)NC1=CC=C(Cl)C(COC2=CN=CC=C2)=C1)N1CCOCC1
MAPK14	DB08091	mitogen-activated protein kinase 14	experimental	3-FLUORO-5-MORPHOLIN-4-YL-N-[3-(2-PYRIDIN-4-YLETHYL)-1H-INDOL-5-YL]BENZAMIDE	FC1=CC(=CC(=C1)C(=O)NC1=CC=C2NC=C(CCC3=CC=NC=C3)C2=C1)N1CCOCC1
MAPK14	DB08092	mitogen-activated protein kinase 14	experimental	3-FLUORO-N-1H-INDOL-5-YL-5-MORPHOLIN-4-YLBENZAMIDE	FC1=CC(=CC(=C1)C(=O)NC1=CC=C2NC=CC2=C1)N1CCOCC1
MAPK14	DB08093	mitogen-activated protein kinase 14	experimental	3-(1-NAPHTHYLMETHOXY)PYRIDIN-2-AMINE	NC1=C(OCC2=CC=CC3=CC=CC=C23)C=CC=N1
MAPK14	DB08095	mitogen-activated protein kinase 14	experimental	3-(2-CHLOROPHENYL)-1-(2-{[(1S)-2-HYDROXY-1,2-DIMETHYLPROPYL]AMINO}PYRIMIDIN-4-YL)-1-(4-METHOXYPHENYL)UREA	COC1=CC=C(C=C1)N(C(=O)NC1=CC=CC=C1Cl)C1=NC(N[C@@H](C)C(C)(C)O)=NC=C1
MAPK14	DB08096	mitogen-activated protein kinase 14	experimental	8-(2-CHLOROPHENYLAMINO)-2-(2,6-DIFLUOROPHENYLAMINO)-9-ETHYL-9H-PURINE-1,7-DIIUM	CCN1C(NC2=CC=CC=C2Cl)=NC2=C1N=C(NC1=C(F)C=CC=C1F)N=C2
MAPK14	DB08097	mitogen-activated protein kinase 14	experimental	2-(2,6-DIFLUOROPHENOXY)-N-(2-FLUOROPHENYL)-9-ISOPROPYL-9H-PURIN-8-AMINE	CC(C)N1C(NC2=CC=CC=C2F)=NC2=CN=C(OC3=C(F)C=CC=C3F)N=C12
MAPK14	DB08242	mitogen-activated protein kinase 14	experimental	N,4-dimethyl-3-[(1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)amino]benzamide	CNC(=O)C1=CC(NC2=C3C=NN(C3=NC=N2)C2=CC=CC=C2)=C(C)C=C1
MAPK14	DB08349	mitogen-activated protein kinase 14	experimental	N-cyclopropyl-3-{[1-(2,4-difluorophenyl)-7-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridin-4-yl]amino}-4-methylbenzamide	CN1C2=C(C=NN2C2=C(F)C=C(F)C=C2)C(NC2=C(C)C=CC(=C2)C(=O)NC2CC2)=CC1=O
MAPK14	DB08351	mitogen-activated protein kinase 14	experimental	N-cyclopropyl-4-methyl-3-{2-[(2-morpholin-4-ylethyl)amino]quinazolin-6-yl}benzamide	CC1=CC=C(C=C1C1=CC2=C(C=C1)N=C(NCCN1CCOCC1)N=C2)C(=O)NC1CC1
MAPK14	DB08352	mitogen-activated protein kinase 14	experimental	6-[4-(2-fluorophenyl)-1,3-oxazol-5-yl]-N-(1-methylethyl)-1,3-benzothiazol-2-amine	CC(C)NC1=NC2=C(S1)C=C(C=C2)C1=C(N=CO1)C1=CC=CC=C1F
MAPK14	DB08395	mitogen-activated protein kinase 14	experimental	2-(ETHOXYMETHYL)-4-(4-FLUOROPHENYL)-3-[2-(2-HYDROXYPHENOXY)PYRIMIDIN-4-YL]ISOXAZOL-5(2H)-ONE	CCOCN1OC(=O)C(=C1C1=CC=NC(OC2=CC=CC=C2O)=N1)C1=CC=C(F)C=C1
MAPK14	DB08423	mitogen-activated protein kinase 14	experimental	[5-AMINO-1-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL][3-(PIPERIDIN-4-YLOXY)PHENYL]METHANONE	NC1=C(C=NN1C1=CC=C(F)C=C1)C(=O)C1=CC(OC2CCNCC2)=CC=C1
MAPK14	DB08424	mitogen-activated protein kinase 14	experimental	[5-AMINO-1-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL](3-{[(2R)-2,3-DIHYDROXYPROPYL]OXY}PHENYL)METHANONE	NC1=C(C=NN1C1=CC=C(F)C=C1)C(=O)C1=CC=CC(OC[C@@H](O)CO)=C1
MAPK14	DB08521	mitogen-activated protein kinase 14	experimental	4-[5-(4-FLUORO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-3H-IMIDAZOL-4-YL]-PYRIDINE	C[S@@](=O)C1=CC=C(C=C1)C1=NC(=C(N1)C1=CC=NC=C1)C1=CC=C(F)C=C1
MAPK14	DB08522	mitogen-activated protein kinase 14	experimental	4-(4-FLUOROPHENYL)-1-CYCLOROPROPYLMETHYL-5-(4-PYRIDYL)-IMIDAZOLE	FC1=CC=C(C=C1)C1=C(N(CC2CC2)C=N1)C1=CC=NC=C1
MAPK14	DB08730	mitogen-activated protein kinase 14	experimental	3-FLUORO-5-MORPHOLIN-4-YL-N-[1-(2-PYRIDIN-4-YLETHYL)-1H-INDOL-6-YL]BENZAMIDE	FC1=CC(=CC(=C1)C(=O)NC1=CC=C2C=CN(CCC3=CC=NC=C3)C2=C1)N1CCOCC1
MAPK14	DB00724	mitogen-activated protein kinase 14	approved; investigational	Imiquimod	CC(C)CN1C=NC2=C1C1=CC=CC=C1N=C2N
MAPK14	DB00122	mitogen-activated protein kinase 14	approved; nutraceutical	Choline	C[N+](C)(C)CCO
MAPK14	DB00864	mitogen-activated protein kinase 14	approved; investigational	Tacrolimus	CO[C@@H]1C[C@@H](CC[C@H]1O)\C=C(/C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H]([C@H](C[C@H]2C)OC)[C@H](C[C@@H](C)C\C(C)=C\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]1C)OC
MAPK14	DB01234	mitogen-activated protein kinase 14	approved; investigational	Dexamethasone	C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
MAPK14	DB00608	mitogen-activated protein kinase 14	approved	Chloroquine	CCN(CC)CCCC(C)NC1=C2C=CC(Cl)=CC2=NC=C1
MAPK14	DB00877	mitogen-activated protein kinase 14	approved; investigational	Sirolimus	CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1O
MAPK14	DB00171	mitogen-activated protein kinase 14	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
MAPK14	DB00398	mitogen-activated protein kinase 14	approved; investigational	Sorafenib	CNC(=O)C1=NC=CC(OC2=CC=C(NC(=O)NC3=CC(=C(Cl)C=C3)C(F)(F)F)C=C2)=C1
MAPK14	DB00125	mitogen-activated protein kinase 14	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
MAPK14	DB00435	mitogen-activated protein kinase 14	approved	Nitric Oxide	[N]=O
MAPKAPK2	DB02010	mitogen-activated protein kinase-activated protein kinase 2	experimental	Staurosporine	CN[C@@H]1C[C@@H]2O[C@](C)([C@@H]1OC)N1C3=C(C=CC=C3)C3=C1C1=C(C4=C(C=CC=C4)N21)C1=C3CNC1=O
MAPKAPK2	DB03431	mitogen-activated protein kinase-activated protein kinase 2	experimental	Adenosine-5'-Diphosphate	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](CO[P@](O)(=O)OP(O)(O)=O)[C@H](O)[C@H]1O
MAPKAPK2	DB07234	mitogen-activated protein kinase-activated protein kinase 2	experimental	3-{[(1R)-1-phenylethyl]amino}-4-(pyridin-4-ylamino)cyclobut-3-ene-1,2-dione	C[C@@H](NC1=C(NC2=CC=NC=C2)C(=O)C1=O)C1=CC=CC=C1
MAPKAPK2	DB07406	mitogen-activated protein kinase-activated protein kinase 2	experimental	(4R)-N-[4-({[2-(DIMETHYLAMINO)ETHYL]AMINO}CARBONYL)-1,3-THIAZOL-2-YL]-4-METHYL-1-OXO-2,3,4,9-TETRAHYDRO-1H-BETA-CARBOLINE-6-CARBOXAMIDE	C[C@H]1CNC(=O)C2=C1C1=CC(=CC=C1N2)C(=O)NC1=NC(=CS1)C(=O)NCCN(C)C
MAPKAPK2	DB07430	mitogen-activated protein kinase-activated protein kinase 2	experimental	(10R)-10-methyl-3-(6-methylpyridin-3-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one	C[C@@H]1CNC2=C(SC3=C2C2=C(C=C3)N=C(C=C2)C2=CN=C(C)C=C2)C(=O)N1
MAPKAPK2	DB07431	mitogen-activated protein kinase-activated protein kinase 2	experimental	(3R)-3-(aminomethyl)-9-methoxy-1,2,3,4-tetrahydro-5H-[1]benzothieno[3,2-e][1,4]diazepin-5-one	COC1=CC2=C(SC3=C2NC[C@@H](CN)NC3=O)C=C1
MAPKAPK2	DB07728	mitogen-activated protein kinase-activated protein kinase 2	experimental	2-[2-(2-FLUOROPHENYL)PYRIDIN-4-YL]-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE	FC1=C(C=CC=C1)C1=CC(=CC=N1)C1=CC2=C(CCNC2=O)N1
MAPKAPK2	DB08358	mitogen-activated protein kinase-activated protein kinase 2	experimental	2-(2-QUINOLIN-3-YLPYRIDIN-4-YL)-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE	O=C1NCCC2=C1C=C(N2)C1=CC(=NC=C1)C1=CC2=C(C=CC=C2)N=C1
MAPKAPK2	DB00143	mitogen-activated protein kinase-activated protein kinase 2	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
MARCKS	DB00864	myristoylated alanine-rich protein kinase C substrate	approved; investigational	Tacrolimus	CO[C@@H]1C[C@@H](CC[C@H]1O)\C=C(/C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H]([C@H](C[C@H]2C)OC)[C@H](C[C@@H](C)C\C(C)=C\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]1C)OC
MARS	DB00145	methionyl-tRNA synthetase	approved; nutraceutical	Glycine	NCC(O)=O
MARS	DB00160	methionyl-tRNA synthetase	approved; nutraceutical	L-Alanine	C[C@H](N)C(O)=O
MARS	DB00125	methionyl-tRNA synthetase	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
MARS	DB00151	methionyl-tRNA synthetase	approved; nutraceutical	L-Cysteine	N[C@@H](CS)C(O)=O
MARS	DB00130	methionyl-tRNA synthetase	approved; nutraceutical; investigational	L-Glutamine	N[C@@H](CCC(N)=O)C(O)=O
MARS	DB00117	methionyl-tRNA synthetase	approved; nutraceutical	L-Histidine	N[C@@H](CC1=CN=CN1)C(O)=O
MARS	DB00149	methionyl-tRNA synthetase	approved; nutraceutical	L-Leucine	CC(C)CC(N)C(O)=O
MARS	DB00123	methionyl-tRNA synthetase	approved; nutraceutical	L-Lysine	NCCCC[C@H](N)C(O)=O
MARS	DB00134	methionyl-tRNA synthetase	approved; nutraceutical	L-Methionine	CSCC[C@H](N)C(O)=O
MARS	DB00120	methionyl-tRNA synthetase	approved; nutraceutical	L-Phenylalanine	N[C@@H](CC1=CC=CC=C1)C(O)=O
MARS	DB00172	methionyl-tRNA synthetase	approved; nutraceutical	L-Proline	OC(=O)[C@@H]1CCCN1
MARS	DB00133	methionyl-tRNA synthetase	approved; nutraceutical	L-Serine	N[C@@H](CO)C(O)=O
MARS	DB00156	methionyl-tRNA synthetase	approved; nutraceutical	L-Threonine	C[C@@H](O)[C@H](N)C(O)=O
MARS	DB00150	methionyl-tRNA synthetase	approved; nutraceutical	L-Tryptophan	N[C@@H](CC1=CNC2=CC=CC=C12)C(O)=O
MARS	DB00135	methionyl-tRNA synthetase	approved; nutraceutical	L-Tyrosine	N[C@@H](CC1=CC=C(O)C=C1)C(O)=O
MARS	DB00161	methionyl-tRNA synthetase	approved; nutraceutical	L-Valine	CC(C)[C@H](N)C(O)=O
MARS2	DB00145	methionyl-tRNA synthetase 2, mitochondrial	approved; nutraceutical	Glycine	NCC(O)=O
MARS2	DB00160	methionyl-tRNA synthetase 2, mitochondrial	approved; nutraceutical	L-Alanine	C[C@H](N)C(O)=O
MARS2	DB00125	methionyl-tRNA synthetase 2, mitochondrial	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
MARS2	DB00151	methionyl-tRNA synthetase 2, mitochondrial	approved; nutraceutical	L-Cysteine	N[C@@H](CS)C(O)=O
MARS2	DB00130	methionyl-tRNA synthetase 2, mitochondrial	approved; nutraceutical; investigational	L-Glutamine	N[C@@H](CCC(N)=O)C(O)=O
MARS2	DB00117	methionyl-tRNA synthetase 2, mitochondrial	approved; nutraceutical	L-Histidine	N[C@@H](CC1=CN=CN1)C(O)=O
MARS2	DB00149	methionyl-tRNA synthetase 2, mitochondrial	approved; nutraceutical	L-Leucine	CC(C)CC(N)C(O)=O
MARS2	DB00123	methionyl-tRNA synthetase 2, mitochondrial	approved; nutraceutical	L-Lysine	NCCCC[C@H](N)C(O)=O
MARS2	DB00134	methionyl-tRNA synthetase 2, mitochondrial	approved; nutraceutical	L-Methionine	CSCC[C@H](N)C(O)=O
MARS2	DB00120	methionyl-tRNA synthetase 2, mitochondrial	approved; nutraceutical	L-Phenylalanine	N[C@@H](CC1=CC=CC=C1)C(O)=O
MARS2	DB00133	methionyl-tRNA synthetase 2, mitochondrial	approved; nutraceutical	L-Serine	N[C@@H](CO)C(O)=O
MARS2	DB00156	methionyl-tRNA synthetase 2, mitochondrial	approved; nutraceutical	L-Threonine	C[C@@H](O)[C@H](N)C(O)=O
MARS2	DB00150	methionyl-tRNA synthetase 2, mitochondrial	approved; nutraceutical	L-Tryptophan	N[C@@H](CC1=CNC2=CC=CC=C12)C(O)=O
MARS2	DB00135	methionyl-tRNA synthetase 2, mitochondrial	approved; nutraceutical	L-Tyrosine	N[C@@H](CC1=CC=C(O)C=C1)C(O)=O
MARS2	DB00161	methionyl-tRNA synthetase 2, mitochondrial	approved; nutraceutical	L-Valine	CC(C)[C@H](N)C(O)=O
MAT1A	DB00118	methionine adenosyltransferase I, alpha	approved; nutraceutical	S-Adenosylmethionine	C[S+](CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C(N)N=CN=C12
MAT1A	DB03191	methionine adenosyltransferase I, alpha	experimental	3-Oxiran-2ylalanine	N[C@@H](C[C@@H]1CO1)C(O)=O
MAT1A	DB03431	methionine adenosyltransferase I, alpha	experimental	Adenosine-5'-Diphosphate	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](CO[P@](O)(=O)OP(O)(O)=O)[C@H](O)[C@H]1O
MAT1A	DB03611	methionine adenosyltransferase I, alpha	experimental	L-2-Amino-4-Methoxy-Cis-but-3-Enoic Acid	CO\C=C\[C@@H](N)C(O)=O
MAT2A	DB00118	methionine adenosyltransferase II, alpha	approved; nutraceutical	S-Adenosylmethionine	C[S+](CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C(N)N=CN=C12
MCCC1	DB00121	methylcrotonoyl-CoA carboxylase 1 (alpha)	approved; nutraceutical	Biotin	OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12
MCCC1	DB00149	methylcrotonoyl-CoA carboxylase 1 (alpha)	approved; nutraceutical	L-Leucine	CC(C)CC(N)C(O)=O
MCCC2	DB00121	methylcrotonoyl-CoA carboxylase 2 (beta)	approved; nutraceutical	Biotin	OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12
MCCC2	DB00149	methylcrotonoyl-CoA carboxylase 2 (beta)	approved; nutraceutical	L-Leucine	CC(C)CC(N)C(O)=O
MCCC2	DB01033	methylcrotonoyl-CoA carboxylase 2 (beta)	approved	Mercaptopurine	S=C1N=CNC2=C1NC=N2
MCCC2	DB00563	methylcrotonoyl-CoA carboxylase 2 (beta)	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
MCEE	DB00121	methylmalonyl CoA epimerase	approved; nutraceutical	Biotin	OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12
MDH1	DB00157	malate dehydrogenase 1, NAD (soluble)	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
MDH1	DB01907	malate dehydrogenase 1, NAD (soluble)	experimental	Nicotinamide-Adenine-Dinucleotide	NC(=O)C1=CC=C[N+](=C1)[C@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@@H]1O
MDH1	DB03461	malate dehydrogenase 1, NAD (soluble)	experimental	2'-Monophosphoadenosine 5'-Diphosphoribose	NC(=O)C1=CC=C[N+](=C1)[C@@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@@H]2O[C@H]([C@H](OP(O)(O)=O)[C@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@H]1O
MDH1	DB00121	malate dehydrogenase 1, NAD (soluble)	approved; nutraceutical	Biotin	OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12
MDH2	DB00157	malate dehydrogenase 2, NAD (mitochondrial)	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
MDH2	DB04272	malate dehydrogenase 2, NAD (mitochondrial)	experimental	Citric Acid	OC(=O)CC(O)(CC(O)=O)C(O)=O
MDH2	DB00121	malate dehydrogenase 2, NAD (mitochondrial)	approved; nutraceutical	Biotin	OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12
ME1	DB00157	malic enzyme 1, NADP(+)-dependent, cytosolic	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
ME1	DB03461	malic enzyme 1, NADP(+)-dependent, cytosolic	experimental	2'-Monophosphoadenosine 5'-Diphosphoribose	NC(=O)C1=CC=C[N+](=C1)[C@@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@@H]2O[C@H]([C@H](OP(O)(O)=O)[C@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@H]1O
ME2	DB00157	malic enzyme 2, NAD(+)-dependent, mitochondrial	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
ME2	DB01677	malic enzyme 2, NAD(+)-dependent, mitochondrial	experimental	Fumarate	[O-]C(=O)\C=C\C([O-])=O
ME2	DB01907	malic enzyme 2, NAD(+)-dependent, mitochondrial	experimental	Nicotinamide-Adenine-Dinucleotide	NC(=O)C1=CC=C[N+](=C1)[C@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@@H]1O
ME2	DB03499	malic enzyme 2, NAD(+)-dependent, mitochondrial	experimental	Malate Ion	O[C@H](CC(O)=O)C([O-])=O
ME2	DB03589	malic enzyme 2, NAD(+)-dependent, mitochondrial	experimental	Alpha-Ketomalonic Acid	OC(=O)C(=O)C(O)=O
ME2	DB03680	malic enzyme 2, NAD(+)-dependent, mitochondrial	experimental	Tartronate	OC(C([O-])=O)C([O-])=O
ME3	DB00157	malic enzyme 3, NADP(+)-dependent, mitochondrial	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
ME3	DB01907	malic enzyme 3, NADP(+)-dependent, mitochondrial	experimental	Nicotinamide-Adenine-Dinucleotide	NC(=O)C1=CC=C[N+](=C1)[C@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@@H]1O
ME3	DB03680	malic enzyme 3, NADP(+)-dependent, mitochondrial	experimental	Tartronate	OC(C([O-])=O)C([O-])=O
ME3	DB00184	malic enzyme 3, NADP(+)-dependent, mitochondrial	approved	Nicotine	CN1CCCC1C1=CN=CC=C1
MED1	DB08696	mediator complex subunit 1	experimental	5-{2-[1-(1-METHYL-PROPYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-2-METHYLENE-CYCLOHEXANE-1,3-DIOL	CC[C@H](C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C/C=C1C[C@@H](O)C(=C)[C@H](O)C1
MED1	DB00755	mediator complex subunit 1	approved; nutraceutical; investigational	Tretinoin	CC(C=CC1=C(C)CCCC1(C)C)=CC=CC(C)=CC(O)=O
MGAM	DB00284	maltase-glucoamylase (alpha-glucosidase)	approved; investigational	Acarbose	C[C@H]1O[C@H](O[C@@H]2[C@@H](CO)O[C@H](O[C@@H]3[C@@H](CO)O[C@@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1N[C@H]1C=C(CO)[C@H](O)[C@H](O)[C@H]1O
MGAM	DB00491	maltase-glucoamylase (alpha-glucosidase)	approved	Miglitol	OCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO
MGAM	DB04878	maltase-glucoamylase (alpha-glucosidase)	approved; investigational	Voglibose	OCC(CO)N[C@H]1C[C@](O)(CO)[C@@H](O)[C@H](O)[C@H]1O
MGAM	DB04465	maltase-glucoamylase (alpha-glucosidase)	experimental	Lactose	OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O
MGST1	DB00143	microsomal glutathione S-transferase 1	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
MGST2	DB00143	microsomal glutathione S-transferase 2	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
MGST2	DB01008	microsomal glutathione S-transferase 2	approved; investigational	Busulfan	CS(=O)(=O)OCCCCOS(C)(=O)=O
MGST2	DB01042	microsomal glutathione S-transferase 2	approved	Melphalan	NC(CC1=CC=C(C=C1)N(CCCl)CCCl)C(O)=O
MGST3	DB00143	microsomal glutathione S-transferase 3	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
MIF	DB01880	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	experimental	3,4-Dihydroxycinnamic Acid	OC(=O)\C=C\C1=CC(O)=C(O)C=C1
MIF	DB02728	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	experimental	7-Hydroxy-2-Oxo-Chromene-3-Carboxylic Acid Ethyl Ester	CCOC(=O)C1=CC2=CC=C(O)C=C2OC1=O
MIF	DB04272	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	experimental	Citric Acid	OC(=O)CC(O)(CC(O)=O)C(O)=O
MIF	DB07718	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	experimental	3-(4-HYDROXY-PHENYL)PYRUVIC ACID	OC(=O)C(=O)CC1=CC=C(O)C=C1
MIF	DB07888	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	experimental	3-(4-HYDROXYPHENYL)-4,5-DIHYDRO-5-ISOXAZOLE-ACETIC ACID METHYL ESTER	COC(=O)C[C@H]1CC(=NO1)C1=CC=C(O)C=C1
MIF	DB08333	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	experimental	4-HYDROXYBENZALDEHYDE O-(CYCLOHEXYLCARBONYL)OXIME	OC1=CC=C(\C=N\OC(=O)C2CCCCC2)C=C1
MIF	DB08334	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	experimental	3-FLUORO-4-HYDROXYBENZALDEHYDE O-(CYCLOHEXYLCARBONYL)OXIME	OC1=CC=C(\C=N\OC(=O)C2CCCCC2)C=C1F
MIF	DB08335	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	experimental	4-HYDROXYBENZALDEHYDE O-(3,3-DIMETHYLBUTANOYL)OXIME	CC(C)(C)CC(=O)O\N=C\C1=CC=C(O)C=C1
MIF	DB08765	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	experimental	6-HYDROXY-1,3-BENZOTHIAZOLE-2-SULFONAMIDE	NS(=O)(=O)C1=NC2=C(S1)C=C(O)C=C2
MLXIPL	DB00131	MLX interacting protein-like	approved; nutraceutical	Adenosine monophosphate	NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
MLXIPL	DB00171	MLX interacting protein-like	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
MMAB	DB00200	methylmalonic aciduria (cobalamin deficiency) cblB type	approved	Hydroxocobalamin	C([C@@H]1[C@]2(CCC(NC[C@H](OP(O[C@@H]3[C@H](O[C@@H]([C@@H]3O)N3C=[N]([Co+]456([N]7=C8C=C9[N]4=C(C(C)=C2N5[C@H]1[C@@]1([N]6=C(C(C)=C7[C@@](CC(N)=O)([C@@H]8CCC(N)=O)C)[C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)C)[C@H](C9(C)C)CCC(N)=O)O)C1=CC(=C(C=C31)C)C)CO)([O-])=O)C)=O)C)C(N)=O
MOCOS	DB00114	molybdenum cofactor sulfurase	nutraceutical	Pyridoxal Phosphate	CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O
MOCOS	DB00993	molybdenum cofactor sulfurase	approved	Azathioprine	CN1C=NC(=C1SC1=NC=NC2=C1NC=N2)[N+]([O-])=O
MPST	DB02761	mercaptopyruvate sulfurtransferase	experimental	S-Mercaptocysteine	N[C@@H](CSS)C(O)=O
MPST	DB03352	mercaptopyruvate sulfurtransferase	experimental	S-Arsonocysteine	N[C@@H](CS[As](O)(O)=O)C(O)=O
MSMO1	DB00157	methylsterol monooxygenase 1	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
MTAP	DB00173	methylthioadenosine phosphorylase	approved; nutraceutical	Adenine	NC1=C2NC=NC2=NC=N1
MTAP	DB02158	methylthioadenosine phosphorylase	experimental	(1s)-1-(9-Deazaadenin-9-Yl)-1,4,5-Trideoxy-1,4-Imino-5-Methylthio-D-Ribitol	CSC[C@H]1N[C@H]([C@H](O)[C@@H]1O)C1=CNC2=C1N=CN[C@H]2N
MTAP	DB02281	methylthioadenosine phosphorylase	experimental	Formycin	Nc1ncnc2c(nnc12)[C@@H]1O[C@@H](CO)[C@H](O)[C@H]1O
MTAP	DB02282	methylthioadenosine phosphorylase	experimental	5'-Deoxy-5'-Methylthioadenosine	CSC[C@@H]1O[C@H]([C@H](O)[C@H]1O)N1C=NC2=C1N=CN=C2N
MTAP	DB02933	methylthioadenosine phosphorylase	experimental	5'-Deoxy-5'-(Methylthio)-Tubercidin	CSC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=CC2=C(N)N=CN=C12
MTHFD1	DB00116	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase	approved; nutraceutical	Tetrahydrofolic acid	NC1=NC(=O)C2=C(NCC(CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)N2)N1
MTHFD1	DB00157	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
MTHFD1	DB02358	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase	experimental	LY374571	NC1=NC(O)=C(N)C(NC(=O)NC2=CC=C(C=C2)C(=O)N[C@H](CCC(O)=O)C(O)=O)=N1
MTHFD1	DB03461	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase	experimental	2'-Monophosphoadenosine 5'-Diphosphoribose	NC(=O)C1=CC=C[N+](=C1)[C@@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@@H]2O[C@H]([C@H](OP(O)(O)=O)[C@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@H]1O
MTHFD1	DB04322	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase	experimental	LY249543	NC1=NC(O)=C2C[C@@H](CCC3=CC=C(C=C3)C(=O)N[C@H](CCC(O)=O)C(O)=O)CNC2=N1
MTHFD1	DB00145	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase	approved; nutraceutical	Glycine	NCC(O)=O
MTHFD1	DB00133	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase	approved; nutraceutical	L-Serine	N[C@@H](CO)C(O)=O
MTHFD1	DB00158	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase	approved; nutraceutical	Folic Acid	NC1=NC(=O)C2=NC(CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)=CN=C2N1
MTHFD1	DB00563	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
MTHFD2	DB00116	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase	approved; nutraceutical	Tetrahydrofolic acid	NC1=NC(=O)C2=C(NCC(CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)N2)N1
MTHFD2	DB00157	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
MTHFD2	DB00563	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
MTHFD2	DB00158	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase	approved; nutraceutical	Folic Acid	NC1=NC(=O)C2=NC(CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)=CN=C2N1
MTHFR	DB03147	methylenetetrahydrofolate reductase (NAD(P)H)	experimental	Flavin-Adenine Dinucleotide	CC1=CC2=C(C=C1C)N(C[C@H](O)[C@H](O)[C@H](O)CO[P@](O)(=O)O[P@@](O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC3=C1N=CN=C3N)C1=NC(=O)NC(=O)C1=N2
MTHFR	DB00115	methylenetetrahydrofolate reductase (NAD(P)H)	approved; nutraceutical	Cyanocobalamin	[C@@H]1([C@H]2N3C4=C(C5=[N]6C(C([C@@H]5CCC(N)=O)(C)C)=CC5=[N]7C(=C(C8=[N]([C@@]2([C@@]([C@@H]8CCC(N)=O)(C)CC(N)=O)C)[Co]367([N]2=CN(C3=CC(=C(C)C=C23)C)[C@H]2O[C@H](CO)[C@@H](OP(O)(=O)O[C@H](C)CNC(=O)CC[C@]14C)[C@H]2O)C#N)C)[C@@]([C@@H]5CCC(N)=O)(C)CC(N)=O)C)CC(N)=O
MTHFR	DB00116	methylenetetrahydrofolate reductase (NAD(P)H)	approved; nutraceutical	Tetrahydrofolic acid	NC1=NC(=O)C2=C(NCC(CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)N2)N1
MTHFR	DB01234	methylenetetrahydrofolate reductase (NAD(P)H)	approved; investigational	Dexamethasone	C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
MTHFR	DB00515	methylenetetrahydrofolate reductase (NAD(P)H)	approved	Cisplatin	N[Pt](N)(Cl)Cl
MTHFR	DB00970	methylenetetrahydrofolate reductase (NAD(P)H)	approved	Dactinomycin	CC(C)C1NC(=O)C(NC(=O)C2=C3N=C4C(OC3=C(C)C=C2)=C(C)C(=O)C(N)=C4C(=O)NC2C(C)OC(=O)C(C(C)C)N(C)C(=O)CN(C)C(=O)C3CCCN3C(=O)C(NC2=O)C(C)C)C(C)OC(=O)C(C(C)C)N(C)C(=O)CN(C)C(=O)C2CCCN2C1=O
MTHFR	DB00313	methylenetetrahydrofolate reductase (NAD(P)H)	approved; investigational	Valproic Acid	CCCC(CCC)C(O)=O
MTHFR	DB00526	methylenetetrahydrofolate reductase (NAD(P)H)	approved; investigational	Oxaliplatin	O=C1O[Pt]2(N[C@@H]3CCCC[C@H]3N2)OC1=O
MTHFR	DB01101	methylenetetrahydrofolate reductase (NAD(P)H)	approved; investigational	Capecitabine	CCCCCOC(=O)NC1=NC(=O)N(C=C1F)[C@@H]1O[C@H](C)[C@@H](O)[C@H]1O
MTHFR	DB00175	methylenetetrahydrofolate reductase (NAD(P)H)	approved	Pravastatin	CC[C@H](C)C(=O)O[C@H]1C[C@H](O)C=C2C=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC(O)=O)[C@@H]12
MTHFR	DB00145	methylenetetrahydrofolate reductase (NAD(P)H)	approved; nutraceutical	Glycine	NCC(O)=O
MTHFR	DB00133	methylenetetrahydrofolate reductase (NAD(P)H)	approved; nutraceutical	L-Serine	N[C@@H](CO)C(O)=O
MTHFR	DB00165	methylenetetrahydrofolate reductase (NAD(P)H)	approved; nutraceutical	Pyridoxine	CC1=NC=C(CO)C(CO)=C1O
MTHFR	DB00531	methylenetetrahydrofolate reductase (NAD(P)H)	approved; investigational	Cyclophosphamide	ClCCN(CCCl)P1(=O)NCCCO1
MTHFR	DB01248	methylenetetrahydrofolate reductase (NAD(P)H)	approved; investigational	Docetaxel	CC(=O)O[C@@]12CO[C@@H]1C[C@H](O)[C@]1(C)[C@@H]2[C@H](OC(=O)C2=CC=CC=C2)[C@]2(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C3=CC=CC=C3)C(C)=C([C@@H](O)C1=O)C2(C)C
MTHFR	DB00997	methylenetetrahydrofolate reductase (NAD(P)H)	approved; investigational	Doxorubicin	COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3O[C@H]3C[C@H](N)[C@H](O)[C@H](C)O3)C(=O)CO)C(O)=C1C2=O
MTHFR	DB01229	methylenetetrahydrofolate reductase (NAD(P)H)	approved	Paclitaxel	CC(=O)O[C@@H]1C2=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)C3=CC=CC=C3)[C@@H]3[C@@]4(CO[C@@H]4C[C@H](O)[C@@]3(C)C1=O)OC(C)=O)C2(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)C1=CC=CC=C1)C1=CC=CC=C1
MTHFR	DB01030	methylenetetrahydrofolate reductase (NAD(P)H)	approved; investigational	Topotecan	CC[C@@]1(O)C(=O)OCC2=C1C=C1N(CC3=CC4=C(C=CC(O)=C4CN(C)C)N=C13)C2=O
MTHFR	DB00293	methylenetetrahydrofolate reductase (NAD(P)H)	approved; investigational	Raltitrexed	CN(CC1=CC2=C(NC(C)=NC2=O)C=C1)C1=CC=C(S1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
MTHFR	DB00795	methylenetetrahydrofolate reductase (NAD(P)H)	approved	Sulfasalazine	OC(=O)C1=CC(=CC=C1O)\N=N\C1=CC=C(C=C1)S(=O)(=O)NC1=NC=CC=C1
MTHFR	DB00987	methylenetetrahydrofolate reductase (NAD(P)H)	approved; investigational	Cytarabine	NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O
MTHFR	DB00694	methylenetetrahydrofolate reductase (NAD(P)H)	approved	Daunorubicin	COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3O[C@H]3C[C@H](N)[C@H](O)[C@H](C)O3)C(C)=O)C(O)=C1C2=O
MTHFR	DB00773	methylenetetrahydrofolate reductase (NAD(P)H)	approved	Etoposide	COC1=CC(=CC(OC)=C1O)[C@H]1[C@@H]2[C@H](COC2=O)[C@H](O[C@@H]2O[C@@H]3CO[C@@H](C)O[C@H]3[C@H](O)[C@H]2O)C2=CC3=C(OCO3)C=C12
MTHFR	DB00650	methylenetetrahydrofolate reductase (NAD(P)H)	approved	Leucovorin	NC1=NC(=O)C2=C(NCC(CNC3=CC=C(C=C3)C(=O)N[C@H](CCC(O)=O)C(O)=O)N2C=O)N1
MTHFR	DB01033	methylenetetrahydrofolate reductase (NAD(P)H)	approved	Mercaptopurine	S=C1N=CNC2=C1NC=N2
MTHFR	DB00563	methylenetetrahydrofolate reductase (NAD(P)H)	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
MTHFR	DB00635	methylenetetrahydrofolate reductase (NAD(P)H)	approved	Prednisone	C[C@]12CC(=O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
MTHFR	DB00541	methylenetetrahydrofolate reductase (NAD(P)H)	approved; investigational	Vincristine	CC[C@]1(O)C[C@H]2CN(C1)CCC1=C(NC3=CC=CC=C13)[C@@](C2)(C(=O)OC)C1=C(OC)C=C2N(C=O)[C@@H]3[C@]4(CCN5CC=C[C@](CC)([C@@H]45)[C@@H](OC(C)=O)[C@]3(O)C(=O)OC)C2=C1
MTHFR	DB00158	methylenetetrahydrofolate reductase (NAD(P)H)	approved; nutraceutical	Folic Acid	NC1=NC(=O)C2=NC(CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)=CN=C2N1
MTHFR	DB00460	methylenetetrahydrofolate reductase (NAD(P)H)	approved; investigational	Verteporfin	COC(=O)CCC1=C2NC(\C=C3/N=C(/C=C4\N\C(=C/C5=N/C(=C\2)/C(CCC(O)=O)=C5C)C(C=C)=C4C)C2=CC=C([C@@H](C(=O)OC)[C@@]32C)C(=O)OC)=C1C
MTHFR	DB00544	methylenetetrahydrofolate reductase (NAD(P)H)	approved	Fluorouracil	FC1=CNC(=O)NC1=O
MTHFR	DB00762	methylenetetrahydrofolate reductase (NAD(P)H)	approved; investigational	Irinotecan	CCC1=C2CN3C(=CC4=C(COC(=O)[C@]4(O)CC)C3=O)C2=NC2=C1C=C(OC(=O)N1CCC(CC1)N1CCCCC1)C=C2
MTHFR	DB00958	methylenetetrahydrofolate reductase (NAD(P)H)	approved	Carboplatin	N.N.O=C1O[Pt]OC(=O)C11CCC1
MTHFR	DB00642	methylenetetrahydrofolate reductase (NAD(P)H)	approved; investigational	Pemetrexed	NC1=NC(=O)C2=C(NC=C2CCC2=CC=C(C=C2)C(=O)N[C@H](CCC(O)=O)C(O)=O)N1
MTOR	DB00337	mechanistic target of rapamycin (serine/threonine kinase)	approved; investigational	Pimecrolimus	CC[C@@H]1\C=C(C)/C[C@H](C)C[C@H](OC)[C@H]2O[C@](O)([C@H](C)C[C@@H]2OC)C(=O)C(=O)N2CCCC[C@H]2C(=O)O[C@@H]([C@@H](C)[C@@H](O)CC1=O)C(\C)=C\[C@@H]1CC[C@H](Cl)[C@@H](C1)OC
MTOR	DB00877	mechanistic target of rapamycin (serine/threonine kinase)	approved; investigational	Sirolimus	CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1O
MTOR	DB01590	mechanistic target of rapamycin (serine/threonine kinase)	approved; investigational	Everolimus	CO[C@@H]1C[C@H](C[C@H](C)C2CC(=O)[C@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@@H](C)C[C@@H](C)\C=C\C=C\C=C(C)\[C@H](C[C@H]3CC[C@H](C)[C@](O)(O3)C(=O)C(=O)N3CCCC[C@@H]3C(=O)O2)OC)CC[C@H]1OCCO
MTOR	DB06287	mechanistic target of rapamycin (serine/threonine kinase)	approved; investigational	Temsirolimus	OCC(C)(CO)C(=O)O[C@@H]1CC[C@@H](C[C@@H](C)[C@@H]2CC(=O)[C@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@@H](OC)C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)C[C@H]1OC
MTR	DB00115	5-methyltetrahydrofolate-homocysteine methyltransferase	approved; nutraceutical	Cyanocobalamin	[C@@H]1([C@H]2N3C4=C(C5=[N]6C(C([C@@H]5CCC(N)=O)(C)C)=CC5=[N]7C(=C(C8=[N]([C@@]2([C@@]([C@@H]8CCC(N)=O)(C)CC(N)=O)C)[Co]367([N]2=CN(C3=CC(=C(C)C=C23)C)[C@H]2O[C@H](CO)[C@@H](OP(O)(=O)O[C@H](C)CNC(=O)CC[C@]14C)[C@H]2O)C#N)C)[C@@]([C@@H]5CCC(N)=O)(C)CC(N)=O)C)CC(N)=O
MTR	DB00116	5-methyltetrahydrofolate-homocysteine methyltransferase	approved; nutraceutical	Tetrahydrofolic acid	NC1=NC(=O)C2=C(NCC(CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)N2)N1
MTR	DB00134	5-methyltetrahydrofolate-homocysteine methyltransferase	approved; nutraceutical	L-Methionine	CSCC[C@H](N)C(O)=O
MTR	DB00200	5-methyltetrahydrofolate-homocysteine methyltransferase	approved	Hydroxocobalamin	C([C@@H]1[C@]2(CCC(NC[C@H](OP(O[C@@H]3[C@H](O[C@@H]([C@@H]3O)N3C=[N]([Co+]456([N]7=C8C=C9[N]4=C(C(C)=C2N5[C@H]1[C@@]1([N]6=C(C(C)=C7[C@@](CC(N)=O)([C@@H]8CCC(N)=O)C)[C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)C)[C@H](C9(C)C)CCC(N)=O)O)C1=CC(=C(C=C31)C)C)CO)([O-])=O)C)=O)C)C(N)=O
MTR	DB03614	5-methyltetrahydrofolate-homocysteine methyltransferase	experimental	Co-Methylcobalamin	C[C@H](CNC(=O)CC[C@]1(C)[C@@H](CC(N)=O)C2=[N+]3C1=C(C)C1=[N+]4C(=CC5=[N+]6C(=C(C)C7=[N+]([C@]2(C)[C@](C)(CC(N)=O)[C@@H]7CCC(N)=O)[Co]346C)[C@](C)(CC(N)=O)[C@H]5CCC(N)=O)C(C)(C)[C@@H]1CCC(N)=O)O[P@](O)(=O)O[C@H]1[C@H](CO)O[C@H]([C@@H]1O)N1C=NC2=C1C=C(C)C(C)=C2
MTR	DB00515	5-methyltetrahydrofolate-homocysteine methyltransferase	approved	Cisplatin	N[Pt](N)(Cl)Cl
MTR	DB00531	5-methyltetrahydrofolate-homocysteine methyltransferase	approved; investigational	Cyclophosphamide	ClCCN(CCCl)P1(=O)NCCCO1
MTR	DB00970	5-methyltetrahydrofolate-homocysteine methyltransferase	approved	Dactinomycin	CC(C)C1NC(=O)C(NC(=O)C2=C3N=C4C(OC3=C(C)C=C2)=C(C)C(=O)C(N)=C4C(=O)NC2C(C)OC(=O)C(C(C)C)N(C)C(=O)CN(C)C(=O)C3CCCN3C(=O)C(NC2=O)C(C)C)C(C)OC(=O)C(C(C)C)N(C)C(=O)CN(C)C(=O)C2CCCN2C1=O
MTR	DB00997	5-methyltetrahydrofolate-homocysteine methyltransferase	approved; investigational	Doxorubicin	COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3O[C@H]3C[C@H](N)[C@H](O)[C@H](C)O3)C(=O)CO)C(O)=C1C2=O
MTR	DB00541	5-methyltetrahydrofolate-homocysteine methyltransferase	approved; investigational	Vincristine	CC[C@]1(O)C[C@H]2CN(C1)CCC1=C(NC3=CC=CC=C13)[C@@](C2)(C(=O)OC)C1=C(OC)C=C2N(C=O)[C@@H]3[C@]4(CCN5CC=C[C@](CC)([C@@H]45)[C@@H](OC(C)=O)[C@]3(O)C(=O)OC)C2=C1
MTR	DB01611	5-methyltetrahydrofolate-homocysteine methyltransferase	approved	Hydroxychloroquine	CCN(CCO)CCCC(C)NC1=C2C=CC(Cl)=CC2=NC=C1
MTR	DB00795	5-methyltetrahydrofolate-homocysteine methyltransferase	approved	Sulfasalazine	OC(=O)C1=CC(=CC=C1O)\N=N\C1=CC=C(C=C1)S(=O)(=O)NC1=NC=CC=C1
MTR	DB00898	5-methyltetrahydrofolate-homocysteine methyltransferase	approved	Ethanol	CCO
MTR	DB00544	5-methyltetrahydrofolate-homocysteine methyltransferase	approved	Fluorouracil	FC1=CNC(=O)NC1=O
MTR	DB00650	5-methyltetrahydrofolate-homocysteine methyltransferase	approved	Leucovorin	NC1=NC(=O)C2=C(NCC(CNC3=CC=C(C=C3)C(=O)N[C@H](CCC(O)=O)C(O)=O)N2C=O)N1
MTR	DB00526	5-methyltetrahydrofolate-homocysteine methyltransferase	approved; investigational	Oxaliplatin	O=C1O[Pt]2(N[C@@H]3CCCC[C@H]3N2)OC1=O
MTR	DB00640	5-methyltetrahydrofolate-homocysteine methyltransferase	approved; investigational	Adenosine	NC1=C2N=CN([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)C2=NC=N1
MTR	DB00158	5-methyltetrahydrofolate-homocysteine methyltransferase	approved; nutraceutical	Folic Acid	NC1=NC(=O)C2=NC(CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)=CN=C2N1
MTR	DB00165	5-methyltetrahydrofolate-homocysteine methyltransferase	approved; nutraceutical	Pyridoxine	CC1=NC=C(CO)C(CO)=C1O
MTR	DB00563	5-methyltetrahydrofolate-homocysteine methyltransferase	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
MTR	DB00460	5-methyltetrahydrofolate-homocysteine methyltransferase	approved; investigational	Verteporfin	COC(=O)CCC1=C2NC(\C=C3/N=C(/C=C4\N\C(=C/C5=N/C(=C\2)/C(CCC(O)=O)=C5C)C(C=C)=C4C)C2=CC=C([C@@H](C(=O)OC)[C@@]32C)C(=O)OC)=C1C
MTTP	DB01094	microsomal triglyceride transfer protein	approved	Hesperetin	COC1=C(O)C=C(C=C1)[C@@H]1CC(=O)C2=C(O)C=C(O)C=C2O1
MUC2	DB01411	mucin 2, oligomeric mucus/gel-forming	approved	Pranlukast	O=C(NC1=CC2=C(C=C1)C(=O)C=C(O2)C1=NNN=N1)C1=CC=C(OCCCCC2=CC=CC=C2)C=C1
MUC2	DB01234	mucin 2, oligomeric mucus/gel-forming	approved; investigational	Dexamethasone	C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
MUC21	DB00564	mucin 21, cell surface associated	approved; investigational	Carbamazepine	NC(=O)N1C2=CC=CC=C2C=CC2=CC=CC=C12
MUC21	DB00252	mucin 21, cell surface associated	approved	Phenytoin	O=C1NC(=O)C(N1)(C1=CC=CC=C1)C1=CC=CC=C1
MUC5AC	DB01234	mucin 5AC, oligomeric mucus/gel-forming	approved; investigational	Dexamethasone	C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
MUT	DB00115	methylmalonyl CoA mutase	approved; nutraceutical	Cyanocobalamin	[C@@H]1([C@H]2N3C4=C(C5=[N]6C(C([C@@H]5CCC(N)=O)(C)C)=CC5=[N]7C(=C(C8=[N]([C@@]2([C@@]([C@@H]8CCC(N)=O)(C)CC(N)=O)C)[Co]367([N]2=CN(C3=CC(=C(C)C=C23)C)[C@H]2O[C@H](CO)[C@@H](OP(O)(=O)O[C@H](C)CNC(=O)CC[C@]14C)[C@H]2O)C#N)C)[C@@]([C@@H]5CCC(N)=O)(C)CC(N)=O)C)CC(N)=O
MUT	DB00200	methylmalonyl CoA mutase	approved	Hydroxocobalamin	C([C@@H]1[C@]2(CCC(NC[C@H](OP(O[C@@H]3[C@H](O[C@@H]([C@@H]3O)N3C=[N]([Co+]456([N]7=C8C=C9[N]4=C(C(C)=C2N5[C@H]1[C@@]1([N]6=C(C(C)=C7[C@@](CC(N)=O)([C@@H]8CCC(N)=O)C)[C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)C)[C@H](C9(C)C)CCC(N)=O)O)C1=CC(=C(C=C31)C)C)CO)([O-])=O)C)=O)C)C(N)=O
MUT	DB00121	methylmalonyl CoA mutase	approved; nutraceutical	Biotin	OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12
MVK	DB04695	mevalonate kinase	experimental	FARNESYL THIOPYROPHOSPHATE	CC(C)=CCC\C(C)=C\CC\C(C)=C/CS[P@@](=O)(O)OP(O)(=O)O
NADK	DB00160	NAD kinase	approved; nutraceutical	L-Alanine	C[C@H](N)C(O)=O
NADK	DB00130	NAD kinase	approved; nutraceutical; investigational	L-Glutamine	N[C@@H](CCC(N)=O)C(O)=O
NADK	DB00150	NAD kinase	approved; nutraceutical	L-Tryptophan	N[C@@H](CC1=CNC2=CC=CC=C12)C(O)=O
NADSYN1	DB00142	NAD synthetase 1	approved; nutraceutical	L-Glutamic Acid	N[C@@H](CCC(O)=O)C(O)=O
NADSYN1	DB00160	NAD synthetase 1	approved; nutraceutical	L-Alanine	C[C@H](N)C(O)=O
NADSYN1	DB00130	NAD synthetase 1	approved; nutraceutical; investigational	L-Glutamine	N[C@@H](CCC(N)=O)C(O)=O
NADSYN1	DB00150	NAD synthetase 1	approved; nutraceutical	L-Tryptophan	N[C@@H](CC1=CNC2=CC=CC=C12)C(O)=O
NAGK	DB00141	N-acetylglucosamine kinase	approved; nutraceutical	N-Acetyl-D-glucosamine	CC(=O)N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O
NAGLU	DB00141	N-acetylglucosaminidase, alpha	approved; nutraceutical	N-Acetyl-D-glucosamine	CC(=O)N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O
NAGS	DB00142	N-acetylglutamate synthase	approved; nutraceutical	L-Glutamic Acid	N[C@@H](CCC(O)=O)C(O)=O
NAGS	DB00125	N-acetylglutamate synthase	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
NAGS	DB03904	N-acetylglutamate synthase	experimental	Urea	NC(N)=O
NAMPT	DB00627	nicotinamide phosphoribosyltransferase	approved; nutraceutical; investigational	Niacin	OC(=O)C1=CN=CC=C1
NAMPT	DB00412	nicotinamide phosphoribosyltransferase	approved; investigational	Rosiglitazone	CN(CCOC1=CC=C(CC2SC(=O)NC2=O)C=C1)C1=CC=CC=N1
NAT1	DB01006	N-acetyltransferase 1 (arylamine N-acetyltransferase)	approved; investigational	Letrozole	N#CC1=CC=C(C=C1)C(N1C=NC=N1)C1=CC=C(C=C1)C#N
NAT1	DB00951	N-acetyltransferase 1 (arylamine N-acetyltransferase)	approved	Isoniazid	NNC(=O)C1=CC=NC=C1
NAT1	DB00259	N-acetyltransferase 1 (arylamine N-acetyltransferase)	approved	Sulfanilamide	NC1=CC=C(C=C1)S(N)(=O)=O
NAT1	DB01015	N-acetyltransferase 1 (arylamine N-acetyltransferase)	approved	Sulfamethoxazole	CC1=CC(NS(=O)(=O)C2=CC=C(N)C=C2)=NO1
NAT2	DB01248	N-acetyltransferase 2 (arylamine N-acetyltransferase)	approved; investigational	Docetaxel	CC(=O)O[C@@]12CO[C@@H]1C[C@H](O)[C@]1(C)[C@@H]2[C@H](OC(=O)C2=CC=CC=C2)[C@]2(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C3=CC=CC=C3)C(C)=C([C@@H](O)C1=O)C2(C)C
NAT2	DB01041	N-acetyltransferase 2 (arylamine N-acetyltransferase)	approved; withdrawn; investigational	Thalidomide	O=C1N(C2CCC(=O)NC2=O)C(=O)C2=CC=CC=C12
NAT2	DB00250	N-acetyltransferase 2 (arylamine N-acetyltransferase)	approved; investigational	Dapsone	NC1=CC=C(C=C1)S(=O)(=O)C1=CC=C(N)C=C1
NAT2	DB01068	N-acetyltransferase 2 (arylamine N-acetyltransferase)	illicit; approved	Clonazepam	[O-][N+](=O)C1=CC2=C(NC(=O)CN=C2C2=CC=CC=C2Cl)C=C1
NAT2	DB00951	N-acetyltransferase 2 (arylamine N-acetyltransferase)	approved	Isoniazid	NNC(=O)C1=CC=NC=C1
NAT2	DB00259	N-acetyltransferase 2 (arylamine N-acetyltransferase)	approved	Sulfanilamide	NC1=CC=C(C=C1)S(N)(=O)=O
NAT2	DB00945	N-acetyltransferase 2 (arylamine N-acetyltransferase)	approved	Acetylsalicylic acid	CC(=O)OC1=CC=CC=C1C(O)=O
NAT2	DB00277	N-acetyltransferase 2 (arylamine N-acetyltransferase)	approved	Theophylline	CN1C2=C(NC=N2)C(=O)N(C)C1=O
NAT2	DB00898	N-acetyltransferase 2 (arylamine N-acetyltransferase)	approved	Ethanol	CCO
NAT2	DB01412	N-acetyltransferase 2 (arylamine N-acetyltransferase)	approved	Theobromine	CN1C=NC2=C1C(=O)NC(=O)N2C
NAT2	DB00286	N-acetyltransferase 2 (arylamine N-acetyltransferase)	approved	Conjugated Estrogens	[Na+].C[C@]12CC[C@H]3[C@@H](CCC4=CC(OS([O-])(=O)=O)=CC=C34)[C@@H]1CCC2=O
NAT2	DB00201	N-acetyltransferase 2 (arylamine N-acetyltransferase)	approved	Caffeine	CN1C=NC2=C1C(=O)N(C)C(=O)N2C
NAT2	DB00811	N-acetyltransferase 2 (arylamine N-acetyltransferase)	approved	Ribavirin	NC(=O)C1=NN(C=N1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
NAT2	DB00514	N-acetyltransferase 2 (arylamine N-acetyltransferase)	approved	Dextromethorphan	COC1=CC2=C(C[C@H]3[C@H]4CCCC[C@@]24CCN3C)C=C1
NAT2	DB01582	N-acetyltransferase 2 (arylamine N-acetyltransferase)	approved	Sulfamethazine	CC1=CC(C)=NC(NS(=O)(=O)C2=CC=C(N)C=C2)=N1
NAT2	DB00563	N-acetyltransferase 2 (arylamine N-acetyltransferase)	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
NAT2	DB00795	N-acetyltransferase 2 (arylamine N-acetyltransferase)	approved	Sulfasalazine	OC(=O)C1=CC(=CC=C1O)\N=N\C1=CC=C(C=C1)S(=O)(=O)NC1=NC=CC=C1
NAT2	DB01015	N-acetyltransferase 2 (arylamine N-acetyltransferase)	approved	Sulfamethoxazole	CC1=CC(NS(=O)(=O)C2=CC=C(N)C=C2)=NO1
NAT2	DB01035	N-acetyltransferase 2 (arylamine N-acetyltransferase)	approved	Procainamide	CCN(CC)CCNC(=O)C1=CC=C(N)C=C1
NAT2	DB01275	N-acetyltransferase 2 (arylamine N-acetyltransferase)	approved	Hydralazine	NNC1=NN=CC2=CC=CC=C12
NCOA1	DB01645	nuclear receptor coactivator 1	experimental	Genistein	OC1=CC=C(C=C1)C1=COC2=C(C(O)=CC(O)=C2)C1=O
NCOA1	DB04652	nuclear receptor coactivator 1	experimental	(11-BETA)-11,21-DIHYDROXY-PREGN-4-ENE-3,20-DIONE	C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)CO
NCOA1	DB06832	nuclear receptor coactivator 1	experimental	2-(3-FLUORO-4-HYDROXYPHENYL)-7-VINYL-1,3-BENZOXAZOL-5-OL	OC1=CC2=C(OC(=N2)C2=CC=C(O)C(F)=C2)C(C=C)=C1
NCOA1	DB06875	nuclear receptor coactivator 1	experimental	3-(3-FLUORO-4-HYDROXYPHENYL)-7-HYDROXY-1-NAPHTHONITRILE	OC1=CC=C2C=C(C=C(C#N)C2=C1)C1=CC=C(O)C(F)=C1
NCOA1	DB06908	nuclear receptor coactivator 1	experimental	(2S)-3-(1-{[2-(2-CHLOROPHENYL)-5-METHYL-1,3-OXAZOL-4-YL]METHYL}-1H-INDOL-5-YL)-2-ETHOXYPROPANOIC ACID	CCO[C@@H](CC1=CC2=C(C=C1)N(CC1=C(C)OC(=N1)C1=C(Cl)C=CC=C1)C=C2)C(O)=O
NCOA1	DB06927	nuclear receptor coactivator 1	experimental	[5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN-7-YL]ACETONITRILE	OC1=CC=C(C=C1)C1=CC2=C(O1)C(CC#N)=CC(O)=C2
NCOA1	DB07009	nuclear receptor coactivator 1	experimental	2-(5-HYDROXY-NAPHTHALEN-1-YL)-1,3-BENZOOXAZOL-6-OL	OC1=CC2=C(C=C1)N=C(O2)C1=C2C=CC=C(O)C2=CC=C1
NCOA1	DB07080	nuclear receptor coactivator 1	experimental	N-(2,2,2-TRIFLUOROETHYL)-N-{4-[2,2,2-TRIFLUORO-1-HYDROXY-1-(TRIFLUOROMETHYL)ETHYL]PHENYL}BENZENESULFONAMIDE	OC(C1=CC=C(C=C1)N(CC(F)(F)F)S(=O)(=O)C1=CC=CC=C1)(C(F)(F)F)C(F)(F)F
NCOA1	DB07119	nuclear receptor coactivator 1	experimental	1-CHLORO-6-(4-HYDROXYPHENYL)-2-NAPHTHOL	OC1=CC=C(C=C1)C1=CC=C2C(C=CC(O)=C2Cl)=C1
NCOA1	DB07150	nuclear receptor coactivator 1	experimental	4-(4-HYDROXYPHENYL)-1-NAPHTHALDEHYDE OXIME	O\N=C\C1=C2C=CC=CC2=C(C=C1)C1=CC=C(O)C=C1
NCOA1	DB07198	nuclear receptor coactivator 1	experimental	5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN-7-CARBONITRILE	OC1=CC=C(C=C1)C1=CC2=C(O1)C(=CC(O)=C2)C#N
NCOA1	DB07215	nuclear receptor coactivator 1	experimental	2-METHYL-2-(4-{[({4-METHYL-2-[4-(TRIFLUOROMETHYL)PHENYL]-1,3-THIAZOL-5-YL}CARBONYL)AMINO]METHYL}PHENOXY)PROPANOIC ACID	CC1=C(SC(=N1)C1=CC=C(C=C1)C(F)(F)F)C(=O)NCC1=CC=C(OC(C)(C)C(O)=O)C=C1
NCOA1	DB07230	nuclear receptor coactivator 1	experimental	3-BROMO-6-HYDROXY-2-(4-HYDROXYPHENYL)-1H-INDEN-1-ONE	OC1=CC=C(C=C1)C1=C(Br)C2=C(C=C(O)C=C2)C1=O
NCOA1	DB07236	nuclear receptor coactivator 1	experimental	3-(6-HYDROXY-NAPHTHALEN-2-YL)-BENZO[D]ISOOXAZOL-6-OL	OC1=CC2=C(C=C1)C(=NO2)C1=CC2=C(C=C1)C=C(O)C=C2
NCOA1	DB07530	nuclear receptor coactivator 1	experimental	(1R,3R)-5-[(2E)-3-{(1S,3R)-2,2,3-trimethyl-3-[6,6,6-trifluoro-5-hydroxy-5-(trifluoromethyl)hex-3-yn-1-yl]cyclopentyl}prop-2-en-1-ylidene]cyclohexane-1,3-diol	O[C@H]1C[C@H](O)CC(=C\C=C\[C@@H]2CC[C@](C)(CCC#CC(O)(C(F)(F)F)C(F)(F)F)C2(C)C)C1
NCOA1	DB07557	nuclear receptor coactivator 1	experimental	(5BETA)-PREGNANE-3,20-DIONE	CC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C
NCOA1	DB07724	nuclear receptor coactivator 1	experimental	3-{5-methoxy-1-[(4-methoxyphenyl)sulfonyl]-1H-indol-3-yl}propanoic acid	COC1=CC=C(C=C1)S(=O)(=O)N1C=C(CCC(O)=O)C2=CC(OC)=CC=C12
NCOA1	DB08220	nuclear receptor coactivator 1	experimental	(8alpha,10alpha,13alpha,17beta)-17-[(4-hydroxyphenyl)carbonyl]androsta-3,5-diene-3-carboxylic acid	C[C@]12CC[C@H]3[C@@H](CC=C4C=C(CC[C@]34C)C(O)=O)[C@@H]1CC[C@@H]2C(=O)C1=CC=C(O)C=C1
NCOA1	DB08231	nuclear receptor coactivator 1	experimental	MYRISTIC ACID	CCCCCCCCCCCCCC(O)=O
NCOA1	DB08483	nuclear receptor coactivator 1	experimental	(2S)-2-methoxy-3-{4-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]-1-benzothiophen-7-yl}propanoic acid	CO[C@@H](CC1=CC=C(OCCC2=C(C)OC(=N2)C2=CC=CC=C2)C2=C1SC=C2)C(O)=O
NCOA1	DB08742	nuclear receptor coactivator 1	experimental	1,3-CYCLOHEXANEDIOL, 4-METHYLENE-5-[(2E)-[(1S,3AS,7AS)-OCTAHYDRO-1-(5-HYDROXY-5-METHYL-1,3-HEXADIYNYL)-7A-METHYL-4H-INDEN-4-YLIDENE]ETHYLIDENE]-, (1R,3S,5Z)	O[C@H]1C[C@H](O)C(=C)\C(=C/C=C2\CCC[C@]3(C)[C@H](CC[C@@H]23)C#CC#CC(C)(O)C)C1
NCOA1	DB00755	nuclear receptor coactivator 1	approved; nutraceutical; investigational	Tretinoin	CC(C=CC1=C(C)CCCC1(C)C)=CC=CC(C)=CC(O)=O
NCOA2	DB01645	nuclear receptor coactivator 2	experimental	Genistein	OC1=CC=C(C=C1)C1=COC2=C(C(O)=CC(O)=C2)C1=O
NCOA2	DB02998	nuclear receptor coactivator 2	experimental	Methyltrienolone	C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3C=C[C@]12C
NCOA2	DB06871	nuclear receptor coactivator 2	experimental	17-METHYL-17-ALPHA-DIHYDROEQUILENIN	C[C@@]1(O)CC[C@H]2C3=C(CC[C@]12C)C1=CC=C(O)C=C1C=C3
NCOA2	DB06898	nuclear receptor coactivator 2	experimental	4-(2-amino-1-methyl-1H-imidazo[4,5-b]pyridin-6-yl)phenol	CN1C(N)=NC2=C1C=C(C=N2)C1=CC=C(O)C=C1
NCOA2	DB07080	nuclear receptor coactivator 2	experimental	N-(2,2,2-TRIFLUOROETHYL)-N-{4-[2,2,2-TRIFLUORO-1-HYDROXY-1-(TRIFLUOROMETHYL)ETHYL]PHENYL}BENZENESULFONAMIDE	OC(C1=CC=C(C=C1)N(CC(F)(F)F)S(=O)(=O)C1=CC=CC=C1)(C(F)(F)F)C(F)(F)F
NCOA2	DB07086	nuclear receptor coactivator 2	experimental	4-[(1S,2S,5S)-5-(HYDROXYMETHYL)-8-METHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL	CC1=CC[C@]2(CO)CO[C@@H]([C@H]1C2)C1=CC=C(O)C=C1
NCOA2	DB07087	nuclear receptor coactivator 2	experimental	4-[(1S,2S,5S,9R)-5-(HYDROXYMETHYL)-8,9-DIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL	C[C@H]1CC[C@]2(CO)CO[C@@H]([C@H]1[C@H]2C)C1=CC=C(O)C=C1
NCOA2	DB07195	nuclear receptor coactivator 2	experimental	4-[(1S,2S,5S)-5-(HYDROXYMETHYL)-6,8,9-TRIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL	C[C@H]1C=C(C)[C@@H]2[C@H](C)[C@@]1(CO)CO[C@@H]2C1=CC=C(O)C=C1
NCOA2	DB07678	nuclear receptor coactivator 2	experimental	(9ALPHA,13BETA,17BETA)-2-[(1Z)-BUT-1-EN-1-YL]ESTRA-1,3,5(10)-TRIENE-3,17-DIOL	CC\C=C\C1=CC2=C(CC[C@@H]3[C@@H]4CC[C@H](O)[C@@]4(C)CC[C@@H]23)C=C1O
NCOA2	DB07707	nuclear receptor coactivator 2	experimental	(9BETA,11ALPHA,13ALPHA,14BETA,17ALPHA)-11-(METHOXYMETHYL)ESTRA-1(10),2,4-TRIENE-3,17-DIOL	COC[C@H]1C[C@]2(C)[C@@H](O)CC[C@H]2[C@@H]2CCC3=CC(O)=CC=C3[C@@H]12
NCOA2	DB07708	nuclear receptor coactivator 2	experimental	3-CHLORO-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL	OC1=CC=C(C=C1)N1N=C2C=CC(O)=CC2=C1Cl
NCOA2	DB07712	nuclear receptor coactivator 2	experimental	3-ETHYL-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL	CCC1=C2C=C(O)C=CC2=NN1C1=CC=C(O)C=C1
NCOA2	DB07863	nuclear receptor coactivator 2	experimental	2-chloro-5-nitro-N-phenylbenzamide	[O-][N+](=O)C1=CC=C(Cl)C(=C1)C(=O)NC1=CC=CC=C1
NCOA2	DB07932	nuclear receptor coactivator 2	experimental	dimethyl (1R,4S)-5,6-bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylate	COC(=O)C1=C([C@H]2O[C@@H]1C(=C2C1=CC=C(O)C=C1)C1=CC=C(O)C=C1)C(=O)OC
NCOA2	DB08047	nuclear receptor coactivator 2	experimental	4-[1-allyl-7-(trifluoromethyl)-1H-indazol-3-yl]benzene-1,3-diol	OC1=CC(O)=C(C=C1)C1=NN(CC=C)C2=C1C=CC=C2C(F)(F)F
NCOA2	DB08048	nuclear receptor coactivator 2	experimental	4-(6-HYDROXY-1H-INDAZOL-3-YL)BENZENE-1,3-DIOL	OC1=CC=C2C(NN=C2C2=CC=C(O)C=C2O)=C1
NCOA2	DB08175	nuclear receptor coactivator 2	experimental	(2E,4E)-11-METHOXY-3,7,11-TRIMETHYLDODECA-2,4-DIENOIC ACID	COC(C)(C)CCC[C@H](C)C\C=C\C(\C)=C\C(O)=O
NCOA2	DB08320	nuclear receptor coactivator 2	experimental	DIETHYL (1R,2S,3R,4S)-5,6-BIS(4-HYDROXYPHENYL)-7-OXABICYCLO[2.2.1]HEPT-5-ENE-2,3-DICARBOXYLATE	CCOC(=O)[C@H]1[C@@H]2O[C@H]([C@H]1C(=O)OCC)C(=C2C1=CC=C(O)C=C1)C1=CC=C(O)C=C1
NCOA2	DB08398	nuclear receptor coactivator 2	experimental	2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE	CN1C(N)=NC2=NC=C(C=C12)C1=CC=CC=C1
NCOA2	DB08402	nuclear receptor coactivator 2	experimental	2-[(2,4-DICHLOROBENZOYL)AMINO]-5-(PYRIMIDIN-2-YLOXY)BENZOIC ACID	OC(=O)C1=C(NC(=O)C2=C(Cl)C=C(Cl)C=C2)C=CC(OC2=NC=CC=N2)=C1
NCOA2	DB08595	nuclear receptor coactivator 2	experimental	4-[(1S,2R,5S)-4,4,8-TRIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL	CC1=CC[C@H]2C[C@@H]1[C@@H](OC2(C)C)C1=CC=C(O)C=C1
NCOA2	DB08601	nuclear receptor coactivator 2	experimental	tributylstannanyl	CCCC[Sn](CCCC)CCCC
NCOA2	DB08773	nuclear receptor coactivator 2	experimental	RALOXIFENE CORE	OC1=CC=C(C=C1)C1=CC2=C(S1)C=C(O)C=C2
NCOR2	DB00755	nuclear receptor corepressor 2	approved; nutraceutical; investigational	Tretinoin	CC(C=CC1=C(C)CCCC1(C)C)=CC=CC(C)=CC(O)=O
NCOR2	DB01001	nuclear receptor corepressor 2	approved	Salbutamol	CC(C)(C)NCC(O)C1=CC(CO)=C(O)C=C1
NDST1	DB01812	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	experimental	Adenosine-3'-5'-Diphosphate	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](COP(O)(O)=O)[C@H](OP(O)(O)=O)[C@H]1O
NEU1	DB00198	sialidase 1 (lysosomal sialidase)	approved	Oseltamivir	CCOC(=O)C1=C[C@@H](OC(CC)CC)[C@H](NC(C)=O)[C@@H](N)C1
NEU2	DB00198	sialidase 2 (cytosolic sialidase)	approved	Oseltamivir	CCOC(=O)C1=C[C@@H](OC(CC)CC)[C@H](NC(C)=O)[C@@H](N)C1
NEU2	DB00558	sialidase 2 (cytosolic sialidase)	approved; investigational	Zanamivir	CC(=O)N[C@@H]1[C@H](C=C(O[C@H]1[C@H](O)[C@H](O)CO)C(O)=O)N=C(N)N
NEU2	DB03991	sialidase 2 (cytosolic sialidase)	experimental	2-Deoxy-2,3-Dehydro-N-Acetyl-Neuraminic Acid	CC(=O)N[C@@H]1[C@@H](O)C=C(O[C@H]1[C@H](O)[C@@H](O)CO)C(O)=O
NEU2	DB07960	sialidase 2 (cytosolic sialidase)	experimental	5-ACETAMIDO-5,6-DIHYDRO-4-HYDROXY-6-ISOBUTOXY-4H-PYRAN-2-CARBOXYLIC ACID	CC(C)CO[C@@H]1OC(=C[C@H](O)[C@H]1NC(C)=O)C(O)=O
NFS1	DB00114	NFS1 nitrogen fixation 1 homolog (S. cerevisiae)	nutraceutical	Pyridoxal Phosphate	CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O
NFS1	DB00151	NFS1 nitrogen fixation 1 homolog (S. cerevisiae)	approved; nutraceutical	L-Cysteine	N[C@@H](CS)C(O)=O
NFS1	DB00160	NFS1 nitrogen fixation 1 homolog (S. cerevisiae)	approved; nutraceutical	L-Alanine	C[C@H](N)C(O)=O
NME1	DB02181	NME/NM23 nucleoside diphosphate kinase 1	experimental	2'-Deoxyguanosine-5'-Triphosphate	NC1=NC2=C(N=CN2[C@H]2C[C@@H](O)[C@H](CO[P@@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)O2)C(=O)N1
NME1	DB02212	NME/NM23 nucleoside diphosphate kinase 1	experimental	Pyrophosphate 2-	O[P@]([O-])(=O)O[P@@](O)([O-])=O
NME1	DB02345	NME/NM23 nucleoside diphosphate kinase 1	experimental	Selenocysteine	N[C@@H](C[SeH])C(O)=O
NME1	DB02569	NME/NM23 nucleoside diphosphate kinase 1	experimental	2',3'-Dehydro-2',3'-Deoxy-Thymidine 5'-Diphosphate	CC1=CN([C@@H]2O[C@H](CO[P@@](O)(=O)OP(O)(O)=O)C=C2)C(=O)NC1=O
NME1	DB02607	NME/NM23 nucleoside diphosphate kinase 1	experimental	Adenosine Phosphonoacetic Acid	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](COC(=O)CP(O)(O)=O)[C@H](O)[C@H]1O
NME1	DB02887	NME/NM23 nucleoside diphosphate kinase 1	experimental	2',3'-Dehydro-2',3'-Deoxy-Thymidine 5'-Triphosphate	CC1=CN([C@@H]2O[C@H](CO[P@@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)C=C2)C(=O)NC1=O
NME1	DB03103	NME/NM23 nucleoside diphosphate kinase 1	experimental	Thymidine-5'- Diphosphate	CC1=CN([C@H]2C[C@@H](O)[C@H](CO[P@](O)(=O)OP(O)(O)=O)O2)C(=O)NC1=O
NME1	DB03431	NME/NM23 nucleoside diphosphate kinase 1	experimental	Adenosine-5'-Diphosphate	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](CO[P@](O)(=O)OP(O)(O)=O)[C@H](O)[C@H]1O
NME1	DB03491	NME/NM23 nucleoside diphosphate kinase 1	experimental	2'-Deoxyguanosine-5'-Diphosphate	NC1=NC2=C(N=CN2[C@H]2C[C@@H](O)[C@H](CO[P@](O)(=O)OP(O)(O)=O)O2)C(=O)N1
NME1	DB04068	NME/NM23 nucleoside diphosphate kinase 1	experimental	Fudp	OP(O)(=O)O[P@@](O)(=O)OC[C@H]1O[C@@H](C[C@@H]1F)N1C=CC(=O)NC1=O
NME1	DB04315	NME/NM23 nucleoside diphosphate kinase 1	experimental	Guanosine-5'-Diphosphate	NC1=NC2=C(N=CN2[C@@H]2O[C@@H](CO[P@](O)(=O)OP(O)(O)=O)[C@H](O)[C@H]2O)C(=O)N1
NME1	DB04366	NME/NM23 nucleoside diphosphate kinase 1	experimental	3'-Deoxy 3'-Amino Adenosine-5'-Diphosphate	N[C@H]1[C@H](CO[P@](O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)N1C=NC2=C1N=CN=C2N
NME1	DB04542	NME/NM23 nucleoside diphosphate kinase 1	experimental	3'-Azido-3'-Deoxythymidine-5'-Diphosphate	CC1=CN([C@H]2C[C@@H](N=[N+]=[N-])[C@H](CO[P@](O)(=O)OP(O)(O)=O)O2)C(=O)NC1=O
NME1	DB00709	NME/NM23 nucleoside diphosphate kinase 1	approved; investigational	Lamivudine	NC1=NC(=O)N(C=C1)[C@@H]1CS[C@H](CO)O1
NME1	DB00171	NME/NM23 nucleoside diphosphate kinase 1	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
NME1	DB00495	NME/NM23 nucleoside diphosphate kinase 1	approved	Zidovudine	CC1=CN([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2)C(=O)NC1=O
NME1	DB00544	NME/NM23 nucleoside diphosphate kinase 1	approved	Fluorouracil	FC1=CNC(=O)NC1=O
NME1	DB00122	NME/NM23 nucleoside diphosphate kinase 1	approved; nutraceutical	Choline	C[N+](C)(C)CCO
NME1	DB00130	NME/NM23 nucleoside diphosphate kinase 1	approved; nutraceutical; investigational	L-Glutamine	N[C@@H](CCC(N)=O)C(O)=O
NME2	DB04315	NME/NM23 nucleoside diphosphate kinase 2	experimental	Guanosine-5'-Diphosphate	NC1=NC2=C(N=CN2[C@@H]2O[C@@H](CO[P@](O)(=O)OP(O)(O)=O)[C@H](O)[C@H]2O)C(=O)N1
NME2	DB00709	NME/NM23 nucleoside diphosphate kinase 2	approved; investigational	Lamivudine	NC1=NC(=O)N(C=C1)[C@@H]1CS[C@H](CO)O1
NME2	DB00171	NME/NM23 nucleoside diphosphate kinase 2	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
NME2	DB00495	NME/NM23 nucleoside diphosphate kinase 2	approved	Zidovudine	CC1=CN([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2)C(=O)NC1=O
NME2	DB00544	NME/NM23 nucleoside diphosphate kinase 2	approved	Fluorouracil	FC1=CNC(=O)NC1=O
NME2	DB00130	NME/NM23 nucleoside diphosphate kinase 2	approved; nutraceutical; investigational	L-Glutamine	N[C@@H](CCC(N)=O)C(O)=O
NMNAT1	DB01907	nicotinamide nucleotide adenylyltransferase 1	experimental	Nicotinamide-Adenine-Dinucleotide	NC(=O)C1=CC=C[N+](=C1)[C@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@@H]1O
NMNAT1	DB03227	nicotinamide nucleotide adenylyltransferase 1	experimental	Nicotinamide Mononucleotide	NC(=O)C1=CC=C[N+](=C1)[C@@H]1O[C@@H](COP(O)(O)=O)[C@H](O)[C@H]1O
NMNAT1	DB04099	nicotinamide nucleotide adenylyltransferase 1	experimental	Deamido-Nad+	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](CO[P@](O)(=O)O[P@@](O)(=O)OC[C@@H]2O[C@H]([C@H](O)[C@H]2O)[N+]2=CC=CC(=C2)C(O)=O)[C@H](O)[C@H]1O
NMNAT1	DB00160	nicotinamide nucleotide adenylyltransferase 1	approved; nutraceutical	L-Alanine	C[C@H](N)C(O)=O
NMNAT1	DB00130	nicotinamide nucleotide adenylyltransferase 1	approved; nutraceutical; investigational	L-Glutamine	N[C@@H](CCC(N)=O)C(O)=O
NMNAT1	DB00150	nicotinamide nucleotide adenylyltransferase 1	approved; nutraceutical	L-Tryptophan	N[C@@H](CC1=CNC2=CC=CC=C12)C(O)=O
NMNAT2	DB00160	nicotinamide nucleotide adenylyltransferase 2	approved; nutraceutical	L-Alanine	C[C@H](N)C(O)=O
NMNAT2	DB00130	nicotinamide nucleotide adenylyltransferase 2	approved; nutraceutical; investigational	L-Glutamine	N[C@@H](CCC(N)=O)C(O)=O
NMNAT2	DB00150	nicotinamide nucleotide adenylyltransferase 2	approved; nutraceutical	L-Tryptophan	N[C@@H](CC1=CNC2=CC=CC=C12)C(O)=O
NMNAT3	DB01907	nicotinamide nucleotide adenylyltransferase 3	experimental	Nicotinamide-Adenine-Dinucleotide	NC(=O)C1=CC=C[N+](=C1)[C@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@@H]1O
NMNAT3	DB02596	nicotinamide nucleotide adenylyltransferase 3	experimental	Alpha,Beta-Methyleneadenosine-5'-Triphosphate	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](CO[P@@](O)(=O)C[P@](O)(=O)OP(O)(O)=O)[C@H](O)[C@H]1O
NMNAT3	DB03227	nicotinamide nucleotide adenylyltransferase 3	experimental	Nicotinamide Mononucleotide	NC(=O)C1=CC=C[N+](=C1)[C@@H]1O[C@@H](COP(O)(O)=O)[C@H](O)[C@H]1O
NMNAT3	DB04099	nicotinamide nucleotide adenylyltransferase 3	experimental	Deamido-Nad+	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](CO[P@](O)(=O)O[P@@](O)(=O)OC[C@@H]2O[C@H]([C@H](O)[C@H]2O)[N+]2=CC=CC(=C2)C(O)=O)[C@H](O)[C@H]1O
NMNAT3	DB00160	nicotinamide nucleotide adenylyltransferase 3	approved; nutraceutical	L-Alanine	C[C@H](N)C(O)=O
NMNAT3	DB00130	nicotinamide nucleotide adenylyltransferase 3	approved; nutraceutical; investigational	L-Glutamine	N[C@@H](CCC(N)=O)C(O)=O
NMNAT3	DB00150	nicotinamide nucleotide adenylyltransferase 3	approved; nutraceutical	L-Tryptophan	N[C@@H](CC1=CNC2=CC=CC=C12)C(O)=O
NNMT	DB00627	nicotinamide N-methyltransferase	approved; nutraceutical; investigational	Niacin	OC(=O)C1=CN=CC=C1
NNMT	DB00640	nicotinamide N-methyltransferase	approved; investigational	Adenosine	NC1=C2N=CN([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)C2=NC=N1
NNMT	DB00134	nicotinamide N-methyltransferase	approved; nutraceutical	L-Methionine	CSCC[C@H](N)C(O)=O
NNMT	DB00158	nicotinamide N-methyltransferase	approved; nutraceutical	Folic Acid	NC1=NC(=O)C2=NC(CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)=CN=C2N1
NNT	DB00157	nicotinamide nucleotide transhydrogenase	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
NNT	DB01763	nicotinamide nucleotide transhydrogenase	experimental	Tatp	NC(=S)C1=CC=C[N+](=C1)[C@@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@@H]2O[C@H]([C@H](OP(O)(O)=O)[C@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@H]1O
NNT	DB03461	nicotinamide nucleotide transhydrogenase	experimental	2'-Monophosphoadenosine 5'-Diphosphoribose	NC(=O)C1=CC=C[N+](=C1)[C@@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@@H]2O[C@H]([C@H](OP(O)(O)=O)[C@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@H]1O
NOS1	DB00155	nitric oxide synthase 1 (neuronal)	approved; nutraceutical	L-Citrulline	N[C@@H](CCCNC(N)=O)C(O)=O
NOS1	DB01821	nitric oxide synthase 1 (neuronal)	experimental	L-N(Omega)-Nitroarginine-2,4-L-Diaminobutyric Amide	NCC[C@@H](NC(=O)[C@@H](N)CCCNC(=N)N[N+]([O-])=O)C(N)=O
NOS1	DB01942	nitric oxide synthase 1 (neuronal)	experimental	Formic Acid	OC=O
NOS1	DB01997	nitric oxide synthase 1 (neuronal)	experimental	3-Bromo-7-Nitroindazole	[O-][N+](=O)c1cccc2c(Br)nnc12
NOS1	DB02027	nitric oxide synthase 1 (neuronal)	experimental	N-{(4s)-4-Amino-5-[(2-Aminoethyl)Amino]Pentyl}-N'-Nitroguanidine	NCCNC[C@@H](N)CCCNC(=N)N[N+]([O-])=O
NOS1	DB02044	nitric oxide synthase 1 (neuronal)	experimental	N-(3-(Aminomethyl)Benzyl)Acetamidine	CC(=N)NCC1=CC=CC(CN)=C1
NOS1	DB02077	nitric oxide synthase 1 (neuronal)	experimental	L-N(Omega)-Nitroarginine-(4r)-Amino-L-Proline Amide	N[C@@H](CCCNC(=N)N[N+]([O-])=O)C(=O)N[C@H]1CN[C@@H](C1)C(N)=O
NOS1	DB02143	nitric oxide synthase 1 (neuronal)	experimental	N-Isopropyl-N'-Hydroxyguanidine	CC(C)NC(=N)NO
NOS1	DB02644	nitric oxide synthase 1 (neuronal)	experimental	N-Omega-Propyl-L-Arginine	CCCNC(=[NH2+])NCCC[C@H](N)C(O)=O
NOS1	DB02692	nitric oxide synthase 1 (neuronal)	experimental	(6r,1'r,2's)-5,6,7,8 Tetrahydrobiopterin	C[C@@H](O)[C@H](O)[C@H]1CNC2=C(N1)C(=O)NC(N)=N2
NOS1	DB02727	nitric oxide synthase 1 (neuronal)	experimental	N-Butyl-N'-Hydroxyguanidine	CCCCNC(=N)NO
NOS1	DB02944	nitric oxide synthase 1 (neuronal)	experimental	Alpha-D-Mannose	OC[C@@H]1O[C@H](O)[C@@H](O)[C@H](O)[C@H]1O
NOS1	DB02991	nitric oxide synthase 1 (neuronal)	experimental	S-Ethyl-N-[4-(Trifluoromethyl)Phenyl]Isothiourea	CCS\C(N)=N\C1=CC=C(C=C1)C(F)(F)F
NOS1	DB03014	nitric oxide synthase 1 (neuronal)	experimental	Heme	CC1=C(CCC(O)=O)C2=CC3=[N+]4C(=CC5=C(C=C)C(C)=C6C=C7C(C=C)=C(C)C8=[N+]7[Fe@]4(N2C1=C8)N56)C(C)=C3CCC(O)=O
NOS1	DB03144	nitric oxide synthase 1 (neuronal)	experimental	N-Omega-Hydroxy-L-Arginine	N[C@@H](CCCNC(=N)NO)C(O)=O
NOS1	DB03147	nitric oxide synthase 1 (neuronal)	experimental	Flavin-Adenine Dinucleotide	CC1=CC2=C(C=C1C)N(C[C@H](O)[C@H](O)[C@H](O)CO[P@](O)(=O)O[P@@](O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC3=C1N=CN=C3N)C1=NC(=O)NC(=O)C1=N2
NOS1	DB03247	nitric oxide synthase 1 (neuronal)	experimental	Riboflavin Monophosphate	CC1=CC2=C(C=C1C)N(C[C@@H](O)[C@@H](O)[C@H](O)COP(O)(O)=O)C1=NC(=O)NC(=O)C1=N2
NOS1	DB03449	nitric oxide synthase 1 (neuronal)	experimental	N-(4-(2-((3-Chlorophenylmethyl)Amino)Ethyl)Phenyl)-2-Thiophecarboxamidine	ClC1=CC=CC(CNCCC2=CC=C(NC(=N)C3=CC=CS3)C=C2)=C1
NOS1	DB03461	nitric oxide synthase 1 (neuronal)	experimental	2'-Monophosphoadenosine 5'-Diphosphoribose	NC(=O)C1=CC=C[N+](=C1)[C@@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@@H]2O[C@H]([C@H](OP(O)(O)=O)[C@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@H]1O
NOS1	DB03707	nitric oxide synthase 1 (neuronal)	experimental	S-Ethyl-N-Phenyl-Isothiourea	CCS\C(N)=N\C1=CC=CC=C1
NOS1	DB03710	nitric oxide synthase 1 (neuronal)	experimental	N5-(1-Imino-3-Butenyl)-L-Ornithine	CCCC(=[NH2+])NCCC[C@@H](N)C(O)=O
NOS1	DB03892	nitric oxide synthase 1 (neuronal)	experimental	5-N-Allyl-Arginine	N[C@@H](CCCN\C(N)=[NH+]\CC=C)C(O)=O
NOS1	DB04223	nitric oxide synthase 1 (neuronal)	experimental	Nitroarginine	N[C@@H](CCCNC(=N)N[N+]([O-])=O)C(O)=O
NOS1	DB08018	nitric oxide synthase 1 (neuronal)	experimental	N-{(3S,4S)-4-[(6-AMINO-4-METHYLPYRIDIN-2-YL)METHYL]PYRROLIDIN-3-YL}-N'-(4-CHLOROBENZYL)ETHANE-1,2-DIAMINE	CC1=CC(C[C@H]2CNC[C@H]2NCCNCC2=CC=C(Cl)C=C2)=NC(N)=C1
NOS1	DB08019	nitric oxide synthase 1 (neuronal)	experimental	N-{(3R,4S)-4-[(6-amino-4-methylpyridin-2-yl)methyl]pyrrolidin-3-yl}-N'-(3-chlorobenzyl)ethane-1,2-diamine	CC1=CC(C[C@H]2CNC[C@@H]2NCCNCC2=CC(Cl)=CC=C2)=NC(N)=C1
NOS1	DB00997	nitric oxide synthase 1 (neuronal)	approved; investigational	Doxorubicin	COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3O[C@H]3C[C@H](N)[C@H](O)[C@H](C)O3)C(=O)CO)C(O)=C1C2=O
NOS1	DB00171	nitric oxide synthase 1 (neuronal)	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
NOS1	DB00125	nitric oxide synthase 1 (neuronal)	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
NOS1	DB00435	nitric oxide synthase 1 (neuronal)	approved	Nitric Oxide	[N]=O
NOS2	DB00125	nitric oxide synthase 2, inducible	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
NOS2	DB00155	nitric oxide synthase 2, inducible	approved; nutraceutical	L-Citrulline	N[C@@H](CCCNC(N)=O)C(O)=O
NOS2	DB01110	nitric oxide synthase 2, inducible	approved; investigational	Miconazole	ClC1=CC(Cl)=C(COC(CN2C=CN=C2)C2=C(Cl)C=C(Cl)C=C2)C=C1
NOS2	DB01234	nitric oxide synthase 2, inducible	approved; investigational	Dexamethasone	C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
NOS2	DB01686	nitric oxide synthase 2, inducible	experimental	N,N-dimethylarginine	N[C@@H](CCC\N=C(/N)N(C)C)C(O)=O
NOS2	DB01835	nitric oxide synthase 2, inducible	experimental	4r-Fluoro-N6-Ethanimidoyl-L-Lysine	CC(=N)NCC[C@@H](F)C[C@H](N)C(O)=O
NOS2	DB01997	nitric oxide synthase 2, inducible	experimental	3-Bromo-7-Nitroindazole	[O-][N+](=O)c1cccc2c(Br)nnc12
NOS2	DB02044	nitric oxide synthase 2, inducible	experimental	N-(3-(Aminomethyl)Benzyl)Acetamidine	CC(=N)NCC1=CC=CC(CN)=C1
NOS2	DB02207	nitric oxide synthase 2, inducible	experimental	7-Nitroindazole	[O-][N+](=O)c1cccc2cnnc12
NOS2	DB02234	nitric oxide synthase 2, inducible	experimental	Ethylisothiourea	CCSC(N)=N
NOS2	DB02462	nitric oxide synthase 2, inducible	experimental	Thiocoumarin	CN(C)CCCOC1=CC(=O)SC2=CC=CC=C12
NOS2	DB02533	nitric oxide synthase 2, inducible	experimental	Aminoguanidine	NNC(N)=N
NOS2	DB02539	nitric oxide synthase 2, inducible	experimental	S-Ethylisothiourea	CCSC(N)=N
NOS2	DB02644	nitric oxide synthase 2, inducible	experimental	N-Omega-Propyl-L-Arginine	CCCNC(=[NH2+])NCCC[C@H](N)C(O)=O
NOS2	DB02692	nitric oxide synthase 2, inducible	experimental	(6r,1'r,2's)-5,6,7,8 Tetrahydrobiopterin	C[C@@H](O)[C@H](O)[C@H]1CNC2=C(N1)C(=O)NC(N)=N2
NOS2	DB03014	nitric oxide synthase 2, inducible	experimental	Heme	CC1=C(CCC(O)=O)C2=CC3=[N+]4C(=CC5=C(C=C)C(C)=C6C=C7C(C=C)=C(C)C8=[N+]7[Fe@]4(N2C1=C8)N56)C(C)=C3CCC(O)=O
NOS2	DB03100	nitric oxide synthase 2, inducible	experimental	6-Nitroindazole	[O-][N+](=O)c1ccc2cnnc2c1
NOS2	DB03144	nitric oxide synthase 2, inducible	experimental	N-Omega-Hydroxy-L-Arginine	N[C@@H](CCCNC(=N)NO)C(O)=O
NOS2	DB03271	nitric oxide synthase 2, inducible	experimental	7,8-Dihydro-L-Biopterin	C[C@@H](O)[C@@H](O)C1=NC2=C(NC1)N=C(N)NC2=O
NOS2	DB03449	nitric oxide synthase 2, inducible	experimental	N-(4-(2-((3-Chlorophenylmethyl)Amino)Ethyl)Phenyl)-2-Thiophecarboxamidine	ClC1=CC=CC(CNCCC2=CC=C(NC(=N)C3=CC=CS3)C=C2)=C1
NOS2	DB03953	nitric oxide synthase 2, inducible	experimental	L-Thiocitrulline	N[C@@H](CCC\N=C(/N)S)C(O)=O
NOS2	DB04400	nitric oxide synthase 2, inducible	experimental	7,8-Dihydrobiopterin	C[C@@H](O)[C@@H](O)C1=NC2=C(NC1)N=C(N)NC2=O
NOS2	DB04534	nitric oxide synthase 2, inducible	experimental	5-Nitroindazole	[O-][N+](=O)c1ccc2nncc2c1
NOS2	DB06879	nitric oxide synthase 2, inducible	experimental	5-(4'-AMINO-1'-ETHYL-5',8'-DIFLUORO-1'H-SPIRO[PIPERIDINE-4,2'-QUINAZOLINE]-1-YLCARBONYL)PICOLINONITRILE	CCN1C2=C(F)C=CC(F)=C2C(N)=NC11CCN(CC1)C(=O)C1=CN=C(CC1)C#N
NOS2	DB06916	nitric oxide synthase 2, inducible	experimental	N-[2-(1,3-BENZODIOXOL-5-YL)ETHYL]-1-[2-(1H-IMIDAZOL-1-YL)-6-METHYLPYRIMIDIN-4-YL]-D-PROLINAMIDE	CC1=CC(=NC(=N1)N1C=CN=C1)N1CCC[C@@H]1C(=O)NCCC1=CC2=C(OCO2)C=C1
NOS2	DB07002	nitric oxide synthase 2, inducible	experimental	4-({4-[(4-methoxypyridin-2-yl)amino]piperidin-1-yl}carbonyl)benzonitrile	COC1=CC=NC(NC2CCN(CC2)C(=O)C2=CC=C(C=C2)C#N)=C1
NOS2	DB07003	nitric oxide synthase 2, inducible	experimental	(2S)-2-methyl-2,3-dihydrothieno[2,3-f][1,4]oxazepin-5-amine	C[C@H]1CN=C(N)C2=C(O1)C=CS2
NOS2	DB07007	nitric oxide synthase 2, inducible	experimental	(3R)-3-[(1,2,3,4-tetrahydroisoquinolin-7-yloxy)methyl]-2,3-dihydrothieno[2,3-f][1,4]oxazepin-5-amine	NC1=N[C@H](COC2=CC=C3CCNCC3=C2)COC2=C1SC=C2
NOS2	DB07008	nitric oxide synthase 2, inducible	experimental	4-(1,3-BENZODIOXOL-5-YLOXY)-2-[4-(1H-IMIDAZOL-1-YL)PHENOXY]PYRIMIDINE	C1OC2=C(O1)C=C(OC1=CC=NC(OC3=CC=C(C=C3)N3C=CN=C3)=N1)C=C2
NOS2	DB07011	nitric oxide synthase 2, inducible	experimental	(3S)-1-(1,3-BENZODIOXOL-5-YLMETHYL)-3-[4-(1H-IMIDAZOL-1-YL)PHENOXY]PIPERIDINE	C(N1CCC[C@@H](C1)OC1=CC=C(C=C1)N1C=CN=C1)C1=CC2=C(OCO2)C=C1
NOS2	DB07029	nitric oxide synthase 2, inducible	experimental	4-(1,3-BENZODIOXOL-5-YLOXY)-2-[4-(1H-IMIDAZOL-1-YL)PHENOXY]-6-METHYLPYRIMIDINE	CC1=NC(OC2=CC=C(C=C2)N2C=CN=C2)=NC(OC2=CC3=C(OCO3)C=C2)=C1
NOS2	DB07306	nitric oxide synthase 2, inducible	experimental	ETHYL 4-[(4-CHLOROPYRIDIN-2-YL)AMINO]PIPERIDINE-1-CARBOXYLATE	CCOC(=O)N1CCC(CC1)NC1=NC=CC(Cl)=C1
NOS2	DB07318	nitric oxide synthase 2, inducible	experimental	N-[2-(4-AMINO-5,8-DIFLUORO-1,2-DIHYDROQUINAZOLIN-2-YL)ETHYL]-3-FURAMIDE	NC1=N[C@H](CCNC(=O)C2=COC=C2)NC2=C(F)C=CC(F)=C12
NOS2	DB07388	nitric oxide synthase 2, inducible	experimental	ETHYL 4-[(4-METHYLPYRIDIN-2-YL)AMINO]PIPERIDINE-1-CARBOXYLATE	CCOC(=O)N1CCC(CC1)NC1=NC=CC(C)=C1
NOS2	DB07389	nitric oxide synthase 2, inducible	experimental	N-[2-(6-AMINO-4-METHYLPYRIDIN-2-YL)ETHYL]-4-CYANOBENZAMIDE	CC1=CC(N)=NC(CCNC(=O)C2=CC=C(C=C2)C#N)=C1
NOS2	DB07405	nitric oxide synthase 2, inducible	experimental	1-(6-CYANO-3-PYRIDYLCARBONYL)-5',8'-DIFLUOROSPIRO[PIPERIDINE-4,2'(1'H)-QUINAZOLINE]-4'-AMINE	NC1=NC2(CCN(CC2)C(=O)C2=CC=C(N=C2)C#N)NC2=C(F)C=CC(F)=C12
NOS2	DB08214	nitric oxide synthase 2, inducible	experimental	4-(1H-IMIDAZOL-1-YL)PHENOL	OC1=CC=C(C=C1)N1C=CN=C1
NOS2	DB08750	nitric oxide synthase 2, inducible	experimental	1-[4-(AMINOMETHYL)BENZOYL]-5'-FLUORO-1'H-SPIRO[PIPERIDINE-4,2'-QUINAZOLIN]-4'-AMINE	NCC1=CC=C(C=C1)C(=O)N1CCC2(CC1)NC1=CC=CC(F)=C1C(N)=N2
NOS2	DB00997	nitric oxide synthase 2, inducible	approved; investigational	Doxorubicin	COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3O[C@H]3C[C@H](N)[C@H](O)[C@H](C)O3)C(=O)CO)C(O)=C1C2=O
NOS2	DB00435	nitric oxide synthase 2, inducible	approved	Nitric Oxide	[N]=O
NOS2	DB00227	nitric oxide synthase 2, inducible	approved; investigational	Lovastatin	CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12
NOS3	DB00125	nitric oxide synthase 3 (endothelial cell)	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
NOS3	DB00155	nitric oxide synthase 3 (endothelial cell)	approved; nutraceutical	L-Citrulline	N[C@@H](CCCNC(N)=O)C(O)=O
NOS3	DB00360	nitric oxide synthase 3 (endothelial cell)	approved; investigational	Tetrahydrobiopterin	CC(O)C(O)C1CNC2=C(N1)C(=O)N=C(N)N2
NOS3	DB01110	nitric oxide synthase 3 (endothelial cell)	approved; investigational	Miconazole	ClC1=CC(Cl)=C(COC(CN2C=CN=C2)C2=C(Cl)C=C(Cl)C=C2)C=C1
NOS3	DB01686	nitric oxide synthase 3 (endothelial cell)	experimental	N,N-dimethylarginine	N[C@@H](CCC\N=C(/N)N(C)C)C(O)=O
NOS3	DB01821	nitric oxide synthase 3 (endothelial cell)	experimental	L-N(Omega)-Nitroarginine-2,4-L-Diaminobutyric Amide	NCC[C@@H](NC(=O)[C@@H](N)CCCNC(=N)N[N+]([O-])=O)C(N)=O
NOS3	DB01833	nitric oxide synthase 3 (endothelial cell)	experimental	L-2-Amino-4-(Guanidinooxy)Butyric Acid	N[C@@H](CCONC(N)=N)C(O)=O
NOS3	DB01997	nitric oxide synthase 3 (endothelial cell)	experimental	3-Bromo-7-Nitroindazole	[O-][N+](=O)c1cccc2c(Br)nnc12
NOS3	DB02027	nitric oxide synthase 3 (endothelial cell)	experimental	N-{(4s)-4-Amino-5-[(2-Aminoethyl)Amino]Pentyl}-N'-Nitroguanidine	NCCNC[C@@H](N)CCCNC(=N)N[N+]([O-])=O
NOS3	DB02044	nitric oxide synthase 3 (endothelial cell)	experimental	N-(3-(Aminomethyl)Benzyl)Acetamidine	CC(=N)NCC1=CC=CC(CN)=C1
NOS3	DB02048	nitric oxide synthase 3 (endothelial cell)	experimental	1,2,4-Triazole-Carboxamidine	NC(=[NH2+])N1C=NC=N1
NOS3	DB02077	nitric oxide synthase 3 (endothelial cell)	experimental	L-N(Omega)-Nitroarginine-(4r)-Amino-L-Proline Amide	N[C@@H](CCCNC(=N)N[N+]([O-])=O)C(=O)N[C@H]1CN[C@@H](C1)C(N)=O
NOS3	DB02141	nitric oxide synthase 3 (endothelial cell)	experimental	S,S'-(1,4-Phenylene-Bis(1,2-Ethanediyl))Bis-Isothiourea	NC(=N)SCCC1=CC=C(CCSC(N)=N)C=C1
NOS3	DB02207	nitric oxide synthase 3 (endothelial cell)	experimental	7-Nitroindazole	[O-][N+](=O)c1cccc2cnnc12
NOS3	DB02234	nitric oxide synthase 3 (endothelial cell)	experimental	Ethylisothiourea	CCSC(N)=N
NOS3	DB02335	nitric oxide synthase 3 (endothelial cell)	experimental	2-Aminothiazoline	NC1=NCCS1
NOS3	DB02589	nitric oxide synthase 3 (endothelial cell)	experimental	Se-Ethyl-Isoselenourea	CC[Se]C(N)=N
NOS3	DB02692	nitric oxide synthase 3 (endothelial cell)	experimental	(6r,1'r,2's)-5,6,7,8 Tetrahydrobiopterin	C[C@@H](O)[C@H](O)[C@H]1CNC2=C(N1)C(=O)NC(N)=N2
NOS3	DB02911	nitric oxide synthase 3 (endothelial cell)	experimental	2,4-Diamino-6-Phenyl-5,6,7,8,-Tetrahydropteridine	NC1=NC2=C(N[C@@H](CN2)C2=CC=CC=C2)C(N)=N1
NOS3	DB02979	nitric oxide synthase 3 (endothelial cell)	experimental	N1,N14-Bis((S-Methyl)Isothioureido)Tetradecane	CS\C(N)=N\CCCCCCCCCCCCCC\N=C(/N)SC
NOS3	DB02994	nitric oxide synthase 3 (endothelial cell)	experimental	Hydroxydimethylarsine Oxide	C[As](C)(O)=O
NOS3	DB03014	nitric oxide synthase 3 (endothelial cell)	experimental	Heme	CC1=C(CCC(O)=O)C2=CC3=[N+]4C(=CC5=C(C=C)C(C)=C6C=C7C(C=C)=C(C)C8=[N+]7[Fe@]4(N2C1=C8)N56)C(C)=C3CCC(O)=O
NOS3	DB03065	nitric oxide synthase 3 (endothelial cell)	experimental	7-Nitroindazole-2-Carboxamidine	NC(=N)N1C=C2C=CC=C(C2=N1)[N+]([O-])=O
NOS3	DB03100	nitric oxide synthase 3 (endothelial cell)	experimental	6-Nitroindazole	[O-][N+](=O)c1ccc2cnnc2c1
NOS3	DB03144	nitric oxide synthase 3 (endothelial cell)	experimental	N-Omega-Hydroxy-L-Arginine	N[C@@H](CCCNC(=N)NO)C(O)=O
NOS3	DB03305	nitric oxide synthase 3 (endothelial cell)	experimental	N5-Iminoethyl-L-Ornithine	CC(=N)NCCC[C@@H](N)C(O)=O
NOS3	DB03332	nitric oxide synthase 3 (endothelial cell)	experimental	5,6-Cyclic-Tetrahydropteridine	NC1=NC2=C(N3[C@@H](COC3=O)CN2)C(=O)N1
NOS3	DB03707	nitric oxide synthase 3 (endothelial cell)	experimental	S-Ethyl-N-Phenyl-Isothiourea	CCS\C(N)=N\C1=CC=CC=C1
NOS3	DB03910	nitric oxide synthase 3 (endothelial cell)	experimental	S,S'-(1,3-Phenylene-Bis(1,2-Ethanediyl))Bis-Isothiourea	NC(=N)SCCC1=CC(CCSC(N)=N)=CC=C1
NOS3	DB03918	nitric oxide synthase 3 (endothelial cell)	experimental	6s-5,6,7,8-Tetrahydrobiopterin	C[C@@H](O)[C@H](O)[C@H]1CNC2=C(N1)C(=O)NC(N)=N2
NOS3	DB03963	nitric oxide synthase 3 (endothelial cell)	experimental	S-(Dimethylarsenic)Cysteine	C[As](C)SC[C@@H](N)C(O)=O
NOS3	DB03974	nitric oxide synthase 3 (endothelial cell)	experimental	L-Homoarginine	N[C@@H](CCCCNC([NH3+])=N)C(O)=O
NOS3	DB04018	nitric oxide synthase 3 (endothelial cell)	experimental	S-Isopropyl-Isothiourea	CC(C)SC(N)=N
NOS3	DB04223	nitric oxide synthase 3 (endothelial cell)	experimental	Nitroarginine	N[C@@H](CCCNC(=N)N[N+]([O-])=O)C(O)=O
NOS3	DB04534	nitric oxide synthase 3 (endothelial cell)	experimental	5-Nitroindazole	[O-][N+](=O)c1ccc2nncc2c1
NOS3	DB04559	nitric oxide synthase 3 (endothelial cell)	experimental	N-(Chlorophenyl)-N'-Hydroxyguanidine	ONC(=N)NC1=CC=C(Cl)C=C1
NOS3	DB07001	nitric oxide synthase 3 (endothelial cell)	experimental	(3S,5E)-3-propyl-3,4-dihydrothieno[2,3-f][1,4]oxazepin-5(2H)-imine	CCC[C@H]1COC2=C(SC=C2)C(=N)N1
NOS3	DB07244	nitric oxide synthase 3 (endothelial cell)	experimental	5-{4-[(3,5-DIFLUOROBENZYL)AMINO]PHENYL}-6-ETHYLPYRIMIDINE-2,4-DIAMINE	CCC1=C(C(N)=NC(N)=N1)C1=CC=C(NCC2=CC(F)=CC(F)=C2)C=C1
NOS3	DB07388	nitric oxide synthase 3 (endothelial cell)	experimental	ETHYL 4-[(4-METHYLPYRIDIN-2-YL)AMINO]PIPERIDINE-1-CARBOXYLATE	CCOC(=O)N1CCC(CC1)NC1=NC=CC(C)=C1
NOS3	DB08018	nitric oxide synthase 3 (endothelial cell)	experimental	N-{(3S,4S)-4-[(6-AMINO-4-METHYLPYRIDIN-2-YL)METHYL]PYRROLIDIN-3-YL}-N'-(4-CHLOROBENZYL)ETHANE-1,2-DIAMINE	CC1=CC(C[C@H]2CNC[C@H]2NCCNCC2=CC=C(Cl)C=C2)=NC(N)=C1
NOS3	DB08019	nitric oxide synthase 3 (endothelial cell)	experimental	N-{(3R,4S)-4-[(6-amino-4-methylpyridin-2-yl)methyl]pyrrolidin-3-yl}-N'-(3-chlorobenzyl)ethane-1,2-diamine	CC1=CC(C[C@H]2CNC[C@@H]2NCCNCC2=CC(Cl)=CC=C2)=NC(N)=C1
NOS3	DB00999	nitric oxide synthase 3 (endothelial cell)	approved	Hydrochlorothiazide	NS(=O)(=O)C1=C(Cl)C=C2NCNS(=O)(=O)C2=C1
NOS3	DB00119	nitric oxide synthase 3 (endothelial cell)	approved; nutraceutical	Pyruvic acid	CC(=O)C(O)=O
NOS3	DB00790	nitric oxide synthase 3 (endothelial cell)	approved	Perindopril	CCC[C@H](N[C@@H](C)C(=O)N1[C@H]2CCCC[C@H]2C[C@H]1C(O)=O)C(=O)OCC
NOS3	DB00584	nitric oxide synthase 3 (endothelial cell)	approved	Enalapril	CCOC(=O)[C@@H](CCC1=CC=CC=C1)N[C@@H](C)C(=O)N1CCC[C@H]1C(O)=O
NOS3	DB00122	nitric oxide synthase 3 (endothelial cell)	approved; nutraceutical	Choline	C[N+](C)(C)CCO
NOS3	DB00394	nitric oxide synthase 3 (endothelial cell)	approved	Beclomethasone	C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
NOS3	DB01222	nitric oxide synthase 3 (endothelial cell)	approved; investigational	Budesonide	CCC[C@H]1O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO
NOS3	DB01410	nitric oxide synthase 3 (endothelial cell)	approved; investigational	Ciclesonide	CC(C)C(=O)OCC(=O)[C@@]12OC(O[C@@H]1C[C@H]1[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@]21C)C1CCCCC1
NOS3	DB01260	nitric oxide synthase 3 (endothelial cell)	approved; investigational	Desonide	CC1(C)O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO
NOS3	DB01234	nitric oxide synthase 3 (endothelial cell)	approved; investigational	Dexamethasone	C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
NOS3	DB00180	nitric oxide synthase 3 (endothelial cell)	approved; investigational	Flunisolide	CC1(C)O[C@@H]2C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO
NOS3	DB00588	nitric oxide synthase 3 (endothelial cell)	approved; investigational	Fluticasone Propionate	CCC(=O)O[C@@]1([C@H](C)C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)C(=O)SCF
NOS3	DB00741	nitric oxide synthase 3 (endothelial cell)	approved	Hydrocortisone	C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
NOS3	DB00443	nitric oxide synthase 3 (endothelial cell)	approved	Betamethasone	C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
NOS3	DB00959	nitric oxide synthase 3 (endothelial cell)	approved	Methylprednisolone	C[C@H]1C[C@H]2[C@@H]3CC[C@](O)(C(=O)CO)[C@@]3(C)C[C@H](O)[C@@H]2[C@@]2(C)C=CC(=O)C=C12
NOS3	DB00764	nitric oxide synthase 3 (endothelial cell)	approved	Mometasone	C[C@@H]1C[C@H]2C3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CCl
NOS3	DB01384	nitric oxide synthase 3 (endothelial cell)	approved	Paramethasone	C[C@@H]1C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
NOS3	DB00860	nitric oxide synthase 3 (endothelial cell)	approved	Prednisolone	C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
NOS3	DB00635	nitric oxide synthase 3 (endothelial cell)	approved	Prednisone	C[C@]12CC(=O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
NOS3	DB00896	nitric oxide synthase 3 (endothelial cell)	approved	Rimexolone	CCC(=O)[C@@]1(C)[C@H](C)CC2C3CCC4=CC(=O)C=C[C@]4(C)C3[C@@H](O)C[C@]12C
NOS3	DB00620	nitric oxide synthase 3 (endothelial cell)	approved	Triamcinolone	C[C@]12C[C@H](O)[C@@]3(F)[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1C[C@@H](O)[C@]2(O)C(=O)CO
NOS3	DB00131	nitric oxide synthase 3 (endothelial cell)	approved; nutraceutical	Adenosine monophosphate	NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
NOS3	DB00435	nitric oxide synthase 3 (endothelial cell)	approved	Nitric Oxide	[N]=O
NOS3	DB00171	nitric oxide synthase 3 (endothelial cell)	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
NOS3	DB01076	nitric oxide synthase 3 (endothelial cell)	approved	Atorvastatin	CC(C)C1=C(C(=O)NC2=CC=CC=C2)C(=C(N1CC[C@@H](O)C[C@@H](O)CC(O)=O)C1=CC=C(F)C=C1)C1=CC=CC=C1
NOS3	DB01098	nitric oxide synthase 3 (endothelial cell)	approved	Rosuvastatin	CC(C)C1=NC(=NC(C2=CC=C(F)C=C2)=C1\C=C\[C@H](O)C[C@@H](O)CC(O)=O)N(C)S(=O)(=O)C
NOS3	DB00675	nitric oxide synthase 3 (endothelial cell)	approved	Tamoxifen	CC\C(=C(/C1=CC=CC=C1)C1=CC=C(OCCN(C)C)C=C1)C1=CC=CC=C1
NOS3	DB01095	nitric oxide synthase 3 (endothelial cell)	approved	Fluvastatin	CC(C)N1C(\C=C\[C@H](O)C[C@H](O)CC(O)=O)=C(C2=CC=C(F)C=C2)C2=CC=CC=C12
NOS3	DB00563	nitric oxide synthase 3 (endothelial cell)	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
NOS3	DB00203	nitric oxide synthase 3 (endothelial cell)	approved; investigational	Sildenafil	CCCC1=NN(C)C2=C1NC(=NC2=O)C1=C(OCC)C=CC(=C1)S(=O)(=O)N1CCN(C)CC1
NOS3	DB03128	nitric oxide synthase 3 (endothelial cell)	experimental	Acetylcholine	CC(=O)OCC[N+](C)(C)C
NOS3	DB00727	nitric oxide synthase 3 (endothelial cell)	approved; investigational	Nitroglycerin	[O-][N+](=O)OCC(CO[N+]([O-])=O)O[N+]([O-])=O
NOS3	DB00388	nitric oxide synthase 3 (endothelial cell)	approved	Phenylephrine	CNC[C@H](O)C1=CC(O)=CC=C1
NOS3	DB01275	nitric oxide synthase 3 (endothelial cell)	approved	Hydralazine	NNC1=NN=CC2=CC=CC=C12
NOS3	DB01115	nitric oxide synthase 3 (endothelial cell)	approved	Nifedipine	COC(=O)C1=C(C)NC(C)=C(C1C1=CC=CC=C1[N+]([O-])=O)C(=O)OC
NOS3	DB00531	nitric oxide synthase 3 (endothelial cell)	approved; investigational	Cyclophosphamide	ClCCN(CCCl)P1(=O)NCCCO1
NOS3	DB00997	nitric oxide synthase 3 (endothelial cell)	approved; investigational	Doxorubicin	COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3O[C@H]3C[C@H](N)[C@H](O)[C@H](C)O3)C(=O)CO)C(O)=C1C2=O
NOS3	DB00544	nitric oxide synthase 3 (endothelial cell)	approved	Fluorouracil	FC1=CNC(=O)NC1=O
NOS3	DB00158	nitric oxide synthase 3 (endothelial cell)	approved; nutraceutical	Folic Acid	NC1=NC(=O)C2=NC(CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)=CN=C2N1
NQO1	DB00170	NAD(P)H dehydrogenase, quinone 1	approved; nutraceutical	Menadione	CC1=CC(=O)C2=CC=CC=C2C1=O
NQO1	DB00266	NAD(P)H dehydrogenase, quinone 1	approved	Dicumarol	OC1=C(CC2=C(O)OC3=CC=CC=C3C2=O)C(=O)C2=CC=CC=C2O1
NQO1	DB01927	NAD(P)H dehydrogenase, quinone 1	experimental	Duroquinone	CC1=C(C)C(=O)C(C)=C(C)C1=O
NQO1	DB02395	NAD(P)H dehydrogenase, quinone 1	experimental	3-Hydroxymethyl-5-Aziridinyl-1methyl-2-[1h-Indole-4,7-Dione]-Propanol	CN1C(CCCO)=C(CO)C2=C1C(=O)C=C(N1CC1)C2=O
NQO1	DB02400	NAD(P)H dehydrogenase, quinone 1	experimental	5-Methoxy-1,2-Dimethyl-3-(4-Nitrophenoxymethyl)Indole-4,7-Dione	COC1=CC(=O)C2=C(C(COC3=CC=C(C=C3)[N+]([O-])=O)=C(C)N2C)C1=O
NQO1	DB02633	NAD(P)H dehydrogenase, quinone 1	experimental	Cibacron Blue	NC1=C(C=C(NC2=CC=C(NC3=NC(Cl)=NC(NC4=CC=CC=C4S(O)(=O)=O)=N3)C(=C2)S(O)(=O)=O)C2=C1C(=O)C1=CC=CC=C1C2=O)S(O)(=O)=O
NQO1	DB03147	NAD(P)H dehydrogenase, quinone 1	experimental	Flavin-Adenine Dinucleotide	CC1=CC2=C(C=C1C)N(C[C@H](O)[C@H](O)[C@H](O)CO[P@](O)(=O)O[P@@](O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC3=C1N=CN=C3N)C1=NC(=O)NC(=O)C1=N2
NQO1	DB03626	NAD(P)H dehydrogenase, quinone 1	experimental	5-Methoxy-1,2-Dimethyl-3-(Phenoxymethyl)Indole-4,7-Dione	COC1=CC(=O)C2=C(C(COC3=CC=CC=C3)=C(C)N2C)C1=O
NQO1	DB04090	NAD(P)H dehydrogenase, quinone 1	experimental	2,5-Diaziridin-1-Yl-3-(Hydroxymethyl)-6-Methylcyclohexa-2,5-Diene-1,4-Dione	CC1=C(N2CC2)C(=O)C(CO)=C(N2CC2)C1=O
NQO1	DB04392	NAD(P)H dehydrogenase, quinone 1	experimental	Bishydroxy[2h-1-Benzopyran-2-One,1,2-Benzopyrone]	O=C1OC2=CC=CC=C2C(=O)[C@@H]1C[C@H]1C(=O)OC2=C(C=CC=C2)C1=O
NQO1	DB07385	NAD(P)H dehydrogenase, quinone 1	experimental	3-(HYDROXYMETHYL)-1-METHYL-5-(2-METHYLAZIRIDIN-1-YL)-2-PHENYL-1H-INDOLE-4,7-DIONE	C[C@@H]1CN1C1=CC(=O)C2=C(C(CO)=C(N2C)C2=CC=CC=C2)C1=O
NQO1	DB00818	NAD(P)H dehydrogenase, quinone 1	approved; investigational	Propofol	CC(C)C1=CC=CC(C(C)C)=C1O
NQO1	DB00997	NAD(P)H dehydrogenase, quinone 1	approved; investigational	Doxorubicin	COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3O[C@H]3C[C@H](N)[C@H](O)[C@H](C)O3)C(=O)CO)C(O)=C1C2=O
NQO1	DB00515	NAD(P)H dehydrogenase, quinone 1	approved	Cisplatin	N[Pt](N)(Cl)Cl
NQO1	DB00305	NAD(P)H dehydrogenase, quinone 1	approved	Mitomycin	CO[C@]12[C@H]3N[C@H]3CN1C1=C([C@H]2COC(N)=O)C(=O)C(N)=C(C)C1=O
NQO1	DB00773	NAD(P)H dehydrogenase, quinone 1	approved	Etoposide	COC1=CC(=CC(OC)=C1O)[C@H]1[C@@H]2[C@H](COC2=O)[C@H](O[C@@H]2O[C@@H]3CO[C@@H](C)O[C@H]3[C@H](O)[C@H]2O)C2=CC3=C(OCO3)C=C12
NQO1	DB00445	NAD(P)H dehydrogenase, quinone 1	approved	Epirubicin	COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3O[C@H]3C[C@H](N)[C@@H](O)[C@H](C)O3)C(=O)CO)C(O)=C1C2=O
NQO1	DB03033	NAD(P)H dehydrogenase, quinone 1	experimental	1-Methyloxy-4-Sulfone-Benzene	COC1=CC=C(C=C1)[S](=O)=O
NQO1	DB01022	NAD(P)H dehydrogenase, quinone 1	approved	Phytonadione	CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC\C(C)=C\CC1=C(C)C(=O)C2=C(C=CC=C2)C1=O
NR1D1	DB01356	nuclear receptor subfamily 1, group D, member 1	approved	Lithium	[Li+]
NSDHL	DB00157	NAD(P) dependent steroid dehydrogenase-like	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
NT5C	DB00987	5', 3'-nucleotidase, cytosolic	approved; investigational	Cytarabine	NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O
NT5C	DB00709	5', 3'-nucleotidase, cytosolic	approved; investigational	Lamivudine	NC1=NC(=O)N(C=C1)[C@@H]1CS[C@H](CO)O1
NT5C	DB02745	5', 3'-nucleotidase, cytosolic	experimental	Uridine	OC[C@@H]1O[C@H]([C@H](O)[C@H]1O)N1C=CC(=O)NC1=O
NT5C	DB00544	5', 3'-nucleotidase, cytosolic	approved	Fluorouracil	FC1=CNC(=O)NC1=O
NT5C1A	DB00640	5'-nucleotidase, cytosolic IA	approved; investigational	Adenosine	NC1=C2N=CN([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)C2=NC=N1
NT5C1A	DB02745	5'-nucleotidase, cytosolic IA	experimental	Uridine	OC[C@@H]1O[C@H]([C@H](O)[C@H]1O)N1C=CC(=O)NC1=O
NT5C1B	DB00640	5'-nucleotidase, cytosolic IB	approved; investigational	Adenosine	NC1=C2N=CN([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)C2=NC=N1
NT5C2	DB00171	5'-nucleotidase, cytosolic II	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
NT5C2	DB00811	5'-nucleotidase, cytosolic II	approved	Ribavirin	NC(=O)C1=NN(C=N1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
NT5C2	DB00173	5'-nucleotidase, cytosolic II	approved; nutraceutical	Adenine	NC1=C2NC=NC2=NC=N1
NT5C2	DB00515	5'-nucleotidase, cytosolic II	approved	Cisplatin	N[Pt](N)(Cl)Cl
NT5C2	DB00441	5'-nucleotidase, cytosolic II	approved	Gemcitabine	NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](CO)[C@@H](O)C1(F)F
NT5C2	DB00987	5'-nucleotidase, cytosolic II	approved; investigational	Cytarabine	NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O
NT5C2	DB00640	5'-nucleotidase, cytosolic II	approved; investigational	Adenosine	NC1=C2N=CN([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)C2=NC=N1
NT5E	DB00806	5'-nucleotidase, ecto (CD73)	approved; investigational	Pentoxifylline	CN1C=NC2=C1C(=O)N(CCCCC(C)=O)C(=O)N2C
NT5E	DB00640	5'-nucleotidase, ecto (CD73)	approved; investigational	Adenosine	NC1=C2N=CN([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)C2=NC=N1
NT5E	DB02745	5'-nucleotidase, ecto (CD73)	experimental	Uridine	OC[C@@H]1O[C@H]([C@H](O)[C@H]1O)N1C=CC(=O)NC1=O
NT5E	DB00352	5'-nucleotidase, ecto (CD73)	approved	Thioguanine	NC1=NC(=S)C2=C(N1)N=CN2
NT5E	DB01033	5'-nucleotidase, ecto (CD73)	approved	Mercaptopurine	S=C1N=CNC2=C1NC=N2
NT5E	DB01120	5'-nucleotidase, ecto (CD73)	approved	Gliclazide	CC1=CC=C(C=C1)S(=O)(=O)NC(=O)NN1CC2CCCC2C1
NT5E	DB00563	5'-nucleotidase, ecto (CD73)	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
NT5E	DB00795	5'-nucleotidase, ecto (CD73)	approved	Sulfasalazine	OC(=O)C1=CC(=CC=C1O)\N=N\C1=CC=C(C=C1)S(=O)(=O)NC1=NC=CC=C1
NT5E	DB02010	5'-nucleotidase, ecto (CD73)	experimental	Staurosporine	CN[C@@H]1C[C@@H]2O[C@](C)([C@@H]1OC)N1C3=C(C=CC=C3)C3=C1C1=C(C4=C(C=CC=C4)N21)C1=C3CNC1=O
NT5M	DB00987	5',3'-nucleotidase, mitochondrial	approved; investigational	Cytarabine	NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O
NT5M	DB02745	5',3'-nucleotidase, mitochondrial	experimental	Uridine	OC[C@@H]1O[C@H]([C@H](O)[C@H]1O)N1C=CC(=O)NC1=O
NUDT9	DB02379	nudix (nucleoside diphosphate linked moiety X)-type motif 9	experimental	Beta-D-Glucose	OC[C@@H]1O[C@H](O)[C@@H](O)[C@H](O)[C@H]1O
NUDT9	DB04352	nudix (nucleoside diphosphate linked moiety X)-type motif 9	experimental	[(2r,3s,4s,5r)-3,4,5-Trihydroxytetrahydrofuran-2-Yl]Methyl Dihydrogen Phosphate	O[C@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@@H]1O
NUP155	DB00682	nucleoporin 155kDa	approved	Warfarin	CC(=O)CC(C1=CC=CC=C1)C1=C(O)OC2=CC=CC=C2C1=O
NUP214	DB00864	nucleoporin 214kDa	approved; investigational	Tacrolimus	CO[C@@H]1C[C@@H](CC[C@H]1O)\C=C(/C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H]([C@H](C[C@H]2C)OC)[C@H](C[C@@H](C)C\C(C)=C\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]1C)OC
OAT	DB00114	ornithine aminotransferase	nutraceutical	Pyridoxal Phosphate	CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O
OAT	DB00129	ornithine aminotransferase	approved; nutraceutical	L-Ornithine	NCCC[C@H](N)C(O)=O
OAT	DB02054	ornithine aminotransferase	experimental	Gabaculine	NC1=CC=CC(=C1)C(O)=O
OAT	DB02821	ornithine aminotransferase	experimental	Canaline	NOCC[C@@H](N)C(O)=O
OAT	DB00125	ornithine aminotransferase	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
OAT	DB03904	ornithine aminotransferase	experimental	Urea	NC(N)=O
OAT	DB00172	ornithine aminotransferase	approved; nutraceutical	L-Proline	OC(=O)[C@@H]1CCCN1
OAZ1	DB00129	ornithine decarboxylase antizyme 1	approved; nutraceutical	L-Ornithine	NCCC[C@H](N)C(O)=O
OAZ2	DB00129	ornithine decarboxylase antizyme 2	approved; nutraceutical	L-Ornithine	NCCC[C@H](N)C(O)=O
OAZ3	DB00129	ornithine decarboxylase antizyme 3	approved; nutraceutical	L-Ornithine	NCCC[C@H](N)C(O)=O
ODC1	DB00114	ornithine decarboxylase 1	nutraceutical	Pyridoxal Phosphate	CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O
ODC1	DB00127	ornithine decarboxylase 1	approved; nutraceutical	Spermine	NCCCNCCCCNCCCN
ODC1	DB01917	ornithine decarboxylase 1	experimental	Putrescine	NCCCCN
ODC1	DB02209	ornithine decarboxylase 1	experimental	Pyridoxine-5'-Phosphate	CC1=NC=C(COP(O)(O)=O)C(CO)=C1O
ODC1	DB02824	ornithine decarboxylase 1	experimental	N-Pyridoxyl-Glycine-5-Monophosphate	CC1=NC=C(COP(O)(O)=O)C(CNCC(O)=O)=C1O
ODC1	DB03856	ornithine decarboxylase 1	experimental	Alpha-Difluoromethylornithine	NCCC[C@@](N)(C(F)F)C(O)=O
ODC1	DB04083	ornithine decarboxylase 1	experimental	N'-Pyridoxyl-Lysine-5'-Monophosphate	CC1=NC=C(COP(O)(O)=O)C(CNCCCC[C@@H](N)C(O)=O)=C1O
ODC1	DB04263	ornithine decarboxylase 1	experimental	G418	CN[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@@H]([C@@H](C)O)[C@H](O)[C@@H](O)[C@@H]3N)[C@H]2O)OC[C@]1(C)O
ODC1	DB00125	ornithine decarboxylase 1	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
ODC1	DB03904	ornithine decarboxylase 1	experimental	Urea	NC(N)=O
ODC1	DB00134	ornithine decarboxylase 1	approved; nutraceutical	L-Methionine	CSCC[C@H](N)C(O)=O
OGDH	DB00157	oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
OPLAH	DB00142	5-oxoprolinase (ATP-hydrolysing)	approved; nutraceutical	L-Glutamic Acid	N[C@@H](CCC(O)=O)C(O)=O
OTC	DB00129	ornithine carbamoyltransferase	approved; nutraceutical	L-Ornithine	NCCC[C@H](N)C(O)=O
OTC	DB00155	ornithine carbamoyltransferase	approved; nutraceutical	L-Citrulline	N[C@@H](CCCNC(N)=O)C(O)=O
OTC	DB02011	ornithine carbamoyltransferase	experimental	N-(Phosphonoacetyl)-L-Ornithine	N[C@@H](CCCNC(=O)CP(O)(O)=O)C(O)=O
OTC	DB03519	ornithine carbamoyltransferase	experimental	2-Amino-Pentanoic Acid	CCC[C@H](N)C(O)=O
OTC	DB04185	ornithine carbamoyltransferase	experimental	Norvaline	CCC[C@H](N)C(O)=O
OTC	DB00125	ornithine carbamoyltransferase	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
OTC	DB03904	ornithine carbamoyltransferase	experimental	Urea	NC(N)=O
OXCT1	DB00139	3-oxoacid CoA transferase 1	approved; nutraceutical	Succinic acid	OC(=O)CCC(O)=O
OXCT1	DB02731	3-oxoacid CoA transferase 1	experimental	Thimerosal	CC[Hg]SC1=CC=CC=C1C(O)=O
OXCT2	DB00139	3-oxoacid CoA transferase 2	approved; nutraceutical	Succinic acid	OC(=O)CCC(O)=O
P4HA1	DB00126	prolyl 4-hydroxylase, alpha polypeptide I	approved; nutraceutical	Vitamin C	OC[C@H](O)[C@H]1OC(=O)C(O)=C1O
P4HA1	DB00139	prolyl 4-hydroxylase, alpha polypeptide I	approved; nutraceutical	Succinic acid	OC(=O)CCC(O)=O
P4HA1	DB00172	prolyl 4-hydroxylase, alpha polypeptide I	approved; nutraceutical	L-Proline	OC(=O)[C@@H]1CCCN1
P4HA1	DB01275	prolyl 4-hydroxylase, alpha polypeptide I	approved	Hydralazine	NNC1=NN=CC2=CC=CC=C12
P4HA2	DB00139	prolyl 4-hydroxylase, alpha polypeptide II	approved; nutraceutical	Succinic acid	OC(=O)CCC(O)=O
P4HA2	DB00172	prolyl 4-hydroxylase, alpha polypeptide II	approved; nutraceutical	L-Proline	OC(=O)[C@@H]1CCCN1
P4HB	DB03615	prolyl 4-hydroxylase, beta polypeptide	experimental	Ribostamycin	NC[C@@H]1O[C@H](O[C@H]2[C@H](N)C[C@H](N)[C@@H](O)[C@@H]2O[C@@H]2O[C@@H](CO)[C@H](O)[C@H]2O)[C@@H](N)[C@H](O)[C@H]1O
P4HB	DB00171	prolyl 4-hydroxylase, beta polypeptide	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
P4HB	DB00119	prolyl 4-hydroxylase, beta polypeptide	approved; nutraceutical	Pyruvic acid	CC(=O)C(O)=O
PABPC1	DB00877	poly(A) binding protein, cytoplasmic 1	approved; investigational	Sirolimus	CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1O
PAFAH1B3	DB07821	platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)	experimental	(1R)-1,2,2-TRIMETHYLPROPYL (R)-METHYLPHOSPHINATE	C[C@@H](OP(C)=O)C(C)(C)C
PAH	DB00120	phenylalanine hydroxylase	approved; nutraceutical	L-Phenylalanine	N[C@@H](CC1=CC=CC=C1)C(O)=O
PAH	DB00360	phenylalanine hydroxylase	approved; investigational	Tetrahydrobiopterin	CC(O)C(O)C1CNC2=C(N1)C(=O)N=C(N)N2
PAH	DB00368	phenylalanine hydroxylase	approved	Norepinephrine	NC[C@H](O)C1=CC(O)=C(O)C=C1
PAH	DB00668	phenylalanine hydroxylase	approved	Epinephrine	CNC[C@H](O)C1=CC(O)=C(O)C=C1
PAH	DB02562	phenylalanine hydroxylase	experimental	Quinonoid 7,8-Tetrahydrobiopterin	C[C@@H](O)[C@H](O)[C@H]1CNC2=NC(N)=NC(=O)C2=N1
PAH	DB02692	phenylalanine hydroxylase	experimental	(6r,1'r,2's)-5,6,7,8 Tetrahydrobiopterin	C[C@@H](O)[C@H](O)[C@H]1CNC2=C(N1)C(=O)NC(N)=N2
PAH	DB03673	phenylalanine hydroxylase	experimental	Beta(2-Thienyl)Alanine	N[C@@H](CC1=CC=CS1)C(O)=O
PAH	DB04400	phenylalanine hydroxylase	experimental	7,8-Dihydrobiopterin	C[C@@H](O)[C@@H](O)C1=NC2=C(NC1)N=C(N)NC2=O
PAH	DB04419	phenylalanine hydroxylase	experimental	Norleucine	CCCC[C@@H](N)C(O)=O
PAH	DB06262	phenylalanine hydroxylase	approved; investigational	Droxidopa	N[C@H]([C@@H](O)C1=CC(O)=C(O)C=C1)C(O)=O
PAH	DB03271	phenylalanine hydroxylase	experimental	7,8-Dihydro-L-Biopterin	C[C@@H](O)[C@@H](O)C1=NC2=C(NC1)N=C(N)NC2=O
PAH	DB00143	phenylalanine hydroxylase	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
PAH	DB00135	phenylalanine hydroxylase	approved; nutraceutical	L-Tyrosine	N[C@@H](CC1=CC=C(O)C=C1)C(O)=O
PAICS	DB00128	phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase	approved; nutraceutical	L-Aspartic Acid	N[C@@H](CC(O)=O)C(O)=O
PAICS	DB00145	phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase	approved; nutraceutical	Glycine	NCC(O)=O
PAICS	DB00130	phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase	approved; nutraceutical; investigational	L-Glutamine	N[C@@H](CCC(N)=O)C(O)=O
PANK2	DB00151	pantothenate kinase 2	approved; nutraceutical	L-Cysteine	N[C@@H](CS)C(O)=O
PAPSS1	DB02661	3'-phosphoadenosine 5'-phosphosulfate synthase 1	experimental	Adenosine-5'-Diphosphate-2',3'-Vanadate	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](CO[P@](O)(=O)OP(O)(O)=O)[C@H]2O[V](=O)(=O)O[C@H]12
PAPSS1	DB03431	3'-phosphoadenosine 5'-phosphosulfate synthase 1	experimental	Adenosine-5'-Diphosphate	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](CO[P@](O)(=O)OP(O)(O)=O)[C@H](O)[C@H]1O
PAPSS1	DB03708	3'-phosphoadenosine 5'-phosphosulfate synthase 1	experimental	Adenosine-5'-Phosphosulfate	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](CO[P@](O)(=O)OS(O)(=O)=O)[C@H](O)[C@H]1O
PAPSS1	DB04077	3'-phosphoadenosine 5'-phosphosulfate synthase 1	experimental	Glycerol	OCC(O)CO
PAPSS1	DB00783	3'-phosphoadenosine 5'-phosphosulfate synthase 1	approved; investigational	Estradiol	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CC[C@@H]2O
PC	DB00119	pyruvate carboxylase	approved; nutraceutical	Pyruvic acid	CC(=O)C(O)=O
PC	DB00121	pyruvate carboxylase	approved; nutraceutical	Biotin	OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12
PC	DB07497	pyruvate carboxylase	experimental	5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL	O=CCCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12
PCBD1	DB00143	pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
PCBD1	DB00120	pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha	approved; nutraceutical	L-Phenylalanine	N[C@@H](CC1=CC=CC=C1)C(O)=O
PCBD1	DB00135	pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha	approved; nutraceutical	L-Tyrosine	N[C@@H](CC1=CC=C(O)C=C1)C(O)=O
PCBD1	DB00360	pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha	approved; investigational	Tetrahydrobiopterin	CC(O)C(O)C1CNC2=C(N1)C(=O)N=C(N)N2
PCCA	DB00121	propionyl CoA carboxylase, alpha polypeptide	approved; nutraceutical	Biotin	OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12
PCCB	DB00121	propionyl CoA carboxylase, beta polypeptide	approved; nutraceutical	Biotin	OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12
PCCB	DB00161	propionyl CoA carboxylase, beta polypeptide	approved; nutraceutical	L-Valine	CC(C)[C@H](N)C(O)=O
PCK1	DB01819	phosphoenolpyruvate carboxykinase 1 (soluble)	experimental	Phosphoenolpyruvate	OC(=O)C(=C)OP(O)(O)=O
PCK1	DB02008	phosphoenolpyruvate carboxykinase 1 (soluble)	experimental	1-(2-Fluorobenzyl)-3-Butyl-8-(N-Acetyl-4-Aminobenzyl)-Xanthine	CCCCN1C2=C(NC(CC3=CC=C(NC(C)=O)C=C3)=N2)C(=O)N(CC2=CC=CC=C2F)C1=O
PCK1	DB03267	phosphoenolpyruvate carboxykinase 1 (soluble)	experimental	1-Allyl-3-Butyl-8-(N-Acetyl-4-Aminobenzyl)-Xanthine	CCCCN1C2=C(NC(CC3=CC=C(NC(C)=O)C=C3)=N2)C(=O)N(CC=C)C1=O
PCK1	DB03725	phosphoenolpyruvate carboxykinase 1 (soluble)	experimental	Phosphomethylphosphonic Acid-Guanylate Ester	NC1=NC2=C(N=CN2[C@@H]2O[C@@H](CO[P@@](O)(=O)O[P@@](O)(=O)CP(O)(O)=O)[C@H](O)[C@H]2O)C(=O)N1
PCK1	DB00121	phosphoenolpyruvate carboxykinase 1 (soluble)	approved; nutraceutical	Biotin	OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12
PCK2	DB00121	phosphoenolpyruvate carboxykinase 2 (mitochondrial)	approved; nutraceutical	Biotin	OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12
PCYT1A	DB00122	phosphate cytidylyltransferase 1, choline, alpha	approved; nutraceutical	Choline	C[N+](C)(C)CCO
PCYT1A	DB00709	phosphate cytidylyltransferase 1, choline, alpha	approved; investigational	Lamivudine	NC1=NC(=O)N(C=C1)[C@@H]1CS[C@H](CO)O1
PCYT1A	DB00171	phosphate cytidylyltransferase 1, choline, alpha	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PCYT1B	DB00122	phosphate cytidylyltransferase 1, choline, beta	approved; nutraceutical	Choline	C[N+](C)(C)CCO
PCYT2	DB00709	phosphate cytidylyltransferase 2, ethanolamine	approved; investigational	Lamivudine	NC1=NC(=O)N(C=C1)[C@@H]1CS[C@H](CO)O1
PDE10A	DB00975	phosphodiesterase 10A	approved	Dipyridamole	OCCN(CCO)C1=NC2=C(N=C(N=C2N2CCCCC2)N(CCO)CCO)C(=N1)N1CCCCC1
PDE10A	DB01113	phosphodiesterase 10A	approved	Papaverine	COC1=C(OC)C=C(CC2=NC=CC3=CC(OC)=C(OC)C=C23)C=C1
PDE10A	DB08383	phosphodiesterase 10A	experimental	4,5-bis(4-methoxyphenyl)-2-thiophen-2-yl-1H-imidazole	COC1=CC=C(C=C1)C1=C(N=C(N1)C1=CC=CS1)C1=CC=C(OC)C=C1
PDE10A	DB08384	phosphodiesterase 10A	experimental	2-({4-[4-(pyridin-4-ylmethyl)-1H-pyrazol-3-yl]phenoxy}methyl)quinoline	C(OC1=CC=C(C=C1)C1=NNC=C1CC1=CC=NC=C1)C1=NC2=CC=CC=C2C=C1
PDE10A	DB08386	phosphodiesterase 10A	experimental	2-{[4-(4-pyridin-4-yl-1H-pyrazol-3-yl)phenoxy]methyl}quinoline	C(OC1=CC=C(C=C1)C1=NNC=C1C1=CC=NC=C1)C1=CC=C2C=CC=CC2=N1
PDE10A	DB08387	phosphodiesterase 10A	experimental	2-{[4-(1-methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)phenoxy]methyl}quinoline	CN1C=C(C(=N1)C1=CC=C(OCC2=NC3=CC=CC=C3C=C2)C=C1)C1=CC=NC=C1
PDE10A	DB08389	phosphodiesterase 10A	experimental	6,7-DIMETHOXY-4-[(3R)-3-(2-NAPHTHYLOXY)PYRROLIDIN-1-YL]QUINAZOLINE	COC1=C(OC)C=C2C(=C1)N=CN=C2N1CC[C@H](C1)OC1=CC2=CC=CC=C2C=C1
PDE10A	DB08391	phosphodiesterase 10A	experimental	6,7-DIMETHOXY-4-[(3R)-3-(QUINOXALIN-2-YLOXY)PYRROLIDIN-1-YL]QUINAZOLINE	COC1=C(OC)C=C2C(=C1)N=CN=C2N1CC[C@H](C1)OC1=NC2=CC=CC=C2N=C1
PDE10A	DB08811	phosphodiesterase 10A	approved	Tofisopam	CCC1C2=CC(OC)=C(OC)C=C2C(=NN=C1C)C1=CC(OC)=C(OC)C=C1
PDE10A	DB01151	phosphodiesterase 10A	approved	Desipramine	CNCCCN1C2=CC=CC=C2CCC2=CC=CC=C12
PDE10A	DB00472	phosphodiesterase 10A	approved	Fluoxetine	CNCCC(OC1=CC=C(C=C1)C(F)(F)F)C1=CC=CC=C1
PDE11A	DB00820	phosphodiesterase 11A	approved; investigational	Tadalafil	CN1CC(=O)N2[C@H](CC3=C(NC4=CC=CC=C34)[C@H]2C2=CC3=C(OCO3)C=C2)C1=O
PDE11A	DB00472	phosphodiesterase 11A	approved	Fluoxetine	CNCCC(OC1=CC=C(C=C1)C(F)(F)F)C1=CC=CC=C1
PDE1A	DB00622	phosphodiesterase 1A, calmodulin-dependent	approved	Nicardipine	COC(=O)C1=C(C)NC(C)=C(C1C1=CC(=CC=C1)[N+]([O-])=O)C(=O)OCCN(C)CC1=CC=CC=C1
PDE1A	DB01023	phosphodiesterase 1A, calmodulin-dependent	approved; investigational	Felodipine	CCOC(=O)C1=C(C)NC(C)=C(C1C1=C(Cl)C(Cl)=CC=C1)C(=O)OC
PDE1A	DB01244	phosphodiesterase 1A, calmodulin-dependent	approved	Bepridil	CC(C)COCC(CN(CC1=CC=CC=C1)C1=CC=CC=C1)N1CCCC1
PDE1A	DB00472	phosphodiesterase 1A, calmodulin-dependent	approved	Fluoxetine	CNCCC(OC1=CC=C(C=C1)C(F)(F)F)C1=CC=CC=C1
PDE1B	DB00622	phosphodiesterase 1B, calmodulin-dependent	approved	Nicardipine	COC(=O)C1=C(C)NC(C)=C(C1C1=CC(=CC=C1)[N+]([O-])=O)C(=O)OCCN(C)CC1=CC=CC=C1
PDE1B	DB01023	phosphodiesterase 1B, calmodulin-dependent	approved; investigational	Felodipine	CCOC(=O)C1=C(C)NC(C)=C(C1C1=C(Cl)C(Cl)=CC=C1)C(=O)OC
PDE1B	DB01244	phosphodiesterase 1B, calmodulin-dependent	approved	Bepridil	CC(C)COCC(CN(CC1=CC=CC=C1)C1=CC=CC=C1)N1CCCC1
PDE1B	DB04530	phosphodiesterase 1B, calmodulin-dependent	experimental	S,S-(2-Hydroxyethyl)Thiocysteine	N[C@@H](CSSCCO)C(O)=O
PDE1B	DB01151	phosphodiesterase 1B, calmodulin-dependent	approved	Desipramine	CNCCCN1C2=CC=CC=C2CCC2=CC=CC=C12
PDE1B	DB00472	phosphodiesterase 1B, calmodulin-dependent	approved	Fluoxetine	CNCCC(OC1=CC=C(C=C1)C(F)(F)F)C1=CC=CC=C1
PDE1C	DB01151	phosphodiesterase 1C, calmodulin-dependent 70kDa	approved	Desipramine	CNCCCN1C2=CC=CC=C2CCC2=CC=CC=C12
PDE2A	DB02315	phosphodiesterase 2A, cGMP-stimulated	experimental	Cyclic Guanosine Monophosphate	NC1=NC2=C(N=CN2[C@H]2O[C@@H]3CO[P@](O)(=O)O[C@@H]3[C@@H]2O)C(=O)N1
PDE2A	DB07954	phosphodiesterase 2A, cGMP-stimulated	experimental	3-ISOBUTYL-1-METHYLXANTHINE	CC(C)CN1C2=C(N=CN2)C(=O)N(C)C1=O
PDE2A	DB08811	phosphodiesterase 2A, cGMP-stimulated	approved	Tofisopam	CCC1C2=CC(OC)=C(OC)C=C2C(=NN=C1C)C1=CC(OC)=C(OC)C=C1
PDE2A	DB00131	phosphodiesterase 2A, cGMP-stimulated	approved; nutraceutical	Adenosine monophosphate	NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PDE2A	DB00125	phosphodiesterase 2A, cGMP-stimulated	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
PDE2A	DB00155	phosphodiesterase 2A, cGMP-stimulated	approved; nutraceutical	L-Citrulline	N[C@@H](CCCNC(N)=O)C(O)=O
PDE2A	DB00435	phosphodiesterase 2A, cGMP-stimulated	approved	Nitric Oxide	[N]=O
PDE2A	DB01151	phosphodiesterase 2A, cGMP-stimulated	approved	Desipramine	CNCCCN1C2=CC=CC=C2CCC2=CC=CC=C12
PDE2A	DB00472	phosphodiesterase 2A, cGMP-stimulated	approved	Fluoxetine	CNCCC(OC1=CC=C(C=C1)C(F)(F)F)C1=CC=CC=C1
PDE3A	DB00235	phosphodiesterase 3A, cGMP-inhibited	approved	Milrinone	CC1=C(C=C(C#N)C(=O)N1)C1=CC=NC=C1
PDE3A	DB00261	phosphodiesterase 3A, cGMP-inhibited	approved	Anagrelide	Cl.ClC1=C(Cl)C2=C(C=C1)N=C1NC(=O)CN1C2
PDE3A	DB00277	phosphodiesterase 3A, cGMP-inhibited	approved	Theophylline	CN1C2=C(NC=N2)C(=O)N(C)C1=O
PDE3A	DB00922	phosphodiesterase 3A, cGMP-inhibited	approved; investigational	Levosimendan	C[C@@H]1CC(=O)NN=C1C1=CC=C(NN=C(C#N)C#N)C=C1
PDE3A	DB01166	phosphodiesterase 3A, cGMP-inhibited	approved	Cilostazol	O=C1CCC2=C(N1)C=CC(OCCCCC1=NN=NN1C1CCCCC1)=C2
PDE3A	DB01223	phosphodiesterase 3A, cGMP-inhibited	approved	Aminophylline	NCCN.CN1C2=C(NC=N2)C(=O)N(C)C1=O.CN1C2=C(NC=N2)C(=O)N(C)C1=O
PDE3A	DB01303	phosphodiesterase 3A, cGMP-inhibited	approved	Oxtriphylline	C[N+](C)(C)CCO.CN1C2=C([N-]C=N2)C(=O)N(C)C1=O
PDE3A	DB01427	phosphodiesterase 3A, cGMP-inhibited	approved	Amrinone	NC1=CC(=CNC1=O)C1=CC=NC=C1
PDE3A	DB04880	phosphodiesterase 3A, cGMP-inhibited	approved; investigational	Enoximone	CSC1=CC=C(C=C1)C(=O)C1=C(C)NC(=O)N1
PDE3A	DB05266	phosphodiesterase 3A, cGMP-inhibited	approved; investigational	Ibudilast	CC(C)C(=O)C1=C2C=CC=CN2N=C1C(C)C
PDE3A	DB08811	phosphodiesterase 3A, cGMP-inhibited	approved	Tofisopam	CCC1C2=CC(OC)=C(OC)C=C2C(=NN=C1C)C1=CC(OC)=C(OC)C=C1
PDE3A	DB00131	phosphodiesterase 3A, cGMP-inhibited	approved; nutraceutical	Adenosine monophosphate	NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PDE3A	DB00125	phosphodiesterase 3A, cGMP-inhibited	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
PDE3A	DB00155	phosphodiesterase 3A, cGMP-inhibited	approved; nutraceutical	L-Citrulline	N[C@@H](CCCNC(N)=O)C(O)=O
PDE3A	DB00435	phosphodiesterase 3A, cGMP-inhibited	approved	Nitric Oxide	[N]=O
PDE3A	DB01151	phosphodiesterase 3A, cGMP-inhibited	approved	Desipramine	CNCCCN1C2=CC=CC=C2CCC2=CC=CC=C12
PDE3A	DB00472	phosphodiesterase 3A, cGMP-inhibited	approved	Fluoxetine	CNCCC(OC1=CC=C(C=C1)C(F)(F)F)C1=CC=CC=C1
PDE3B	DB01640	phosphodiesterase 3B, cGMP-inhibited	experimental	(5r)-6-(4-{[2-(3-Iodobenzyl)-3-Oxocyclohex-1-En-1-Yl]Amino}Phenyl)-5-Methyl-4,5-Dihydropyridazin-3(2h)-One	C[C@H]1CC(=O)NN=C1C1=CC=C(NC2=C(CC3=CC=CC(I)=C3)C(=O)CCC2)C=C1
PDE3B	DB01970	phosphodiesterase 3B, cGMP-inhibited	experimental	Hg9a-9, Nonanoyl-N-Hydroxyethylglucamide	CCCCCCCCC(=O)N(CCO)C[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)CO
PDE3B	DB07954	phosphodiesterase 3B, cGMP-inhibited	experimental	3-ISOBUTYL-1-METHYLXANTHINE	CC(C)CN1C2=C(N=CN2)C(=O)N(C)C1=O
PDE3B	DB00131	phosphodiesterase 3B, cGMP-inhibited	approved; nutraceutical	Adenosine monophosphate	NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PDE3B	DB00125	phosphodiesterase 3B, cGMP-inhibited	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
PDE3B	DB00155	phosphodiesterase 3B, cGMP-inhibited	approved; nutraceutical	L-Citrulline	N[C@@H](CCCNC(N)=O)C(O)=O
PDE3B	DB00435	phosphodiesterase 3B, cGMP-inhibited	approved	Nitric Oxide	[N]=O
PDE4A	DB00277	phosphodiesterase 4A, cAMP-specific	approved	Theophylline	CN1C2=C(NC=N2)C(=O)N(C)C1=O
PDE4A	DB00651	phosphodiesterase 4A, cAMP-specific	approved	Dyphylline	CN1C2=C(N(CC(O)CO)C=N2)C(=O)N(C)C1=O
PDE4A	DB00806	phosphodiesterase 4A, cAMP-specific	approved; investigational	Pentoxifylline	CN1C=NC2=C1C(=O)N(CCCCC(C)=O)C(=O)N2C
PDE4A	DB00824	phosphodiesterase 4A, cAMP-specific	approved	Enprofylline	CCCN1C2=C(NC=N2)C(=O)NC1=O
PDE4A	DB00920	phosphodiesterase 4A, cAMP-specific	approved	Ketotifen	CN1CCC(CC1)=C1C2=C(SC=C2)C(=O)CC2=CC=CC=C12
PDE4A	DB00975	phosphodiesterase 4A, cAMP-specific	approved	Dipyridamole	OCCN(CCO)C1=NC2=C(N=C(N=C2N2CCCCC2)N(CCO)CCO)C(=N1)N1CCCCC1
PDE4A	DB01088	phosphodiesterase 4A, cAMP-specific	approved; investigational	Iloprost	CC#CCC(C)C(O)\C=C\C1C(O)CC2C\C(CC12)=C\CCCC(=O)OCC(=O)C1=CC=CC=C1
PDE4A	DB01303	phosphodiesterase 4A, cAMP-specific	approved	Oxtriphylline	C[N+](C)(C)CCO.CN1C2=C([N-]C=N2)C(=O)N(C)C1=O
PDE4A	DB01791	phosphodiesterase 4A, cAMP-specific	experimental	Piclamilast	COC1=CC=C(C=C1OC1CCCC1)C(=O)NC1=C(Cl)C=NC=C1Cl
PDE4A	DB05266	phosphodiesterase 4A, cAMP-specific	approved; investigational	Ibudilast	CC(C)C(=O)C1=C2C=CC=CN2N=C1C(C)C
PDE4A	DB06751	phosphodiesterase 4A, cAMP-specific	approved	Drotaverine	CCOC1=C(OCC)C=C(\C=C2/NCCC3=CC(OCC)=C(OCC)C=C23)C=C1
PDE4A	DB06842	phosphodiesterase 4A, cAMP-specific	experimental	(4R)-4-(3-butoxy-4-methoxybenzyl)imidazolidin-2-one	CCCCOC1=C(OC)C=CC(C[C@@H]2CNC(=O)N2)=C1
PDE4A	DB08299	phosphodiesterase 4A, cAMP-specific	experimental	4-[8-(3-nitrophenyl)-1,7-naphthyridin-6-yl]benzoic acid	OC(=O)C1=CC=C(C=C1)C1=NC(C2=CC=CC(=C2)[N+]([O-])=O)=C2N=CC=CC2=C1
PDE4A	DB08811	phosphodiesterase 4A, cAMP-specific	approved	Tofisopam	CCC1C2=CC(OC)=C(OC)C=C2C(=NN=C1C)C1=CC(OC)=C(OC)C=C1
PDE4A	DB01151	phosphodiesterase 4A, cAMP-specific	approved	Desipramine	CNCCCN1C2=CC=CC=C2CCC2=CC=CC=C12
PDE4A	DB00472	phosphodiesterase 4A, cAMP-specific	approved	Fluoxetine	CNCCC(OC1=CC=C(C=C1)C(F)(F)F)C1=CC=CC=C1
PDE4B	DB00131	phosphodiesterase 4B, cAMP-specific	approved; nutraceutical	Adenosine monophosphate	NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PDE4B	DB00201	phosphodiesterase 4B, cAMP-specific	approved	Caffeine	CN1C=NC2=C1C(=O)N(C)C(=O)N2C
PDE4B	DB00277	phosphodiesterase 4B, cAMP-specific	approved	Theophylline	CN1C2=C(NC=N2)C(=O)N(C)C1=O
PDE4B	DB00651	phosphodiesterase 4B, cAMP-specific	approved	Dyphylline	CN1C2=C(N(CC(O)CO)C=N2)C(=O)N(C)C1=O
PDE4B	DB00806	phosphodiesterase 4B, cAMP-specific	approved; investigational	Pentoxifylline	CN1C=NC2=C1C(=O)N(CCCCC(C)=O)C(=O)N2C
PDE4B	DB00824	phosphodiesterase 4B, cAMP-specific	approved	Enprofylline	CCCN1C2=C(NC=N2)C(=O)NC1=O
PDE4B	DB00920	phosphodiesterase 4B, cAMP-specific	approved	Ketotifen	CN1CCC(CC1)=C1C2=C(SC=C2)C(=O)CC2=CC=CC=C12
PDE4B	DB01088	phosphodiesterase 4B, cAMP-specific	approved; investigational	Iloprost	CC#CCC(C)C(O)\C=C\C1C(O)CC2C\C(CC12)=C\CCCC(=O)OCC(=O)C1=CC=CC=C1
PDE4B	DB01113	phosphodiesterase 4B, cAMP-specific	approved	Papaverine	COC1=C(OC)C=C(CC2=NC=CC3=CC(OC)=C(OC)C=C23)C=C1
PDE4B	DB01412	phosphodiesterase 4B, cAMP-specific	approved	Theobromine	CN1C=NC2=C1C(=O)NC(=O)N2C
PDE4B	DB01427	phosphodiesterase 4B, cAMP-specific	approved	Amrinone	NC1=CC(=CNC1=O)C1=CC=NC=C1
PDE4B	DB01647	phosphodiesterase 4B, cAMP-specific	experimental	(R)-Mesopram	CCCOC1=CC(=CC=C1OC)[C@]1(C)CNC(=O)O1
PDE4B	DB01791	phosphodiesterase 4B, cAMP-specific	experimental	Piclamilast	COC1=CC=C(C=C1OC1CCCC1)C(=O)NC1=C(Cl)C=NC=C1Cl
PDE4B	DB01954	phosphodiesterase 4B, cAMP-specific	experimental	4-[3-(Cyclopentyloxy)-4-Methoxyphenyl]-2-Pyrrolidinone	COC1=C(OC2CCCC2)C=C(C=C1)[C@@H]1CNC(=O)C1
PDE4B	DB01959	phosphodiesterase 4B, cAMP-specific	experimental	3,5-Dimethyl-1-(3-Nitrophenyl)-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester	CCOC(=O)C1=C(C)N(N=C1C)C1=CC(=CC=C1)[N+]([O-])=O
PDE4B	DB02660	phosphodiesterase 4B, cAMP-specific	experimental	Filaminast	COC1=CC=C(C=C1OC1CCCC1)C(\C)=N\OC(N)=O
PDE4B	DB03349	phosphodiesterase 4B, cAMP-specific	experimental	8-Bromo-Adenosine-5'-Monophosphate	NC1=NC=NC2=C1N=C(Br)N2[C@@H]1O[C@@H](COP(O)(O)=O)[C@H](O)[C@H]1O
PDE4B	DB03606	phosphodiesterase 4B, cAMP-specific	experimental	(S)-Rolipram	COC1=CC=C(C=C1OC1CCCC1)[C@@H]1CNC(=O)C1
PDE4B	DB03807	phosphodiesterase 4B, cAMP-specific	experimental	1-(2-Chlorophenyl)-3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester	CCOC(=O)C1=C(C)N(N=C1C)C1=C(Cl)C=CC=C1
PDE4B	DB03849	phosphodiesterase 4B, cAMP-specific	experimental	Cis-4-Cyano-4-[3-(Cyclopentyloxy)-4-Methoxyphenyl]Cyclohexanecarboxylic Acid	COC1=CC=C(C=C1OC1CCCC1)[C@@]1(CC[C@@H](CC1)C(O)=O)C#N
PDE4B	DB04149	phosphodiesterase 4B, cAMP-specific	experimental	(R)-Rolipram	COC1=CC=C(C=C1OC1CCCC1)[C@@H]1CNC(=O)C1
PDE4B	DB04530	phosphodiesterase 4B, cAMP-specific	experimental	S,S-(2-Hydroxyethyl)Thiocysteine	N[C@@H](CSSCCO)C(O)=O
PDE4B	DB05266	phosphodiesterase 4B, cAMP-specific	approved; investigational	Ibudilast	CC(C)C(=O)C1=C2C=CC=CN2N=C1C(C)C
PDE4B	DB06909	phosphodiesterase 4B, cAMP-specific	experimental	1-ethyl-N-(phenylmethyl)-4-(tetrahydro-2H-pyran-4-ylamino)-1H-pyrazolo[3,4-b]pyridine-5-carboxamide	CCN1N=CC2=C1N=CC(C(=O)NCC1=CC=CC=C1)=C2NC1CCOCC1
PDE4B	DB08299	phosphodiesterase 4B, cAMP-specific	experimental	4-[8-(3-nitrophenyl)-1,7-naphthyridin-6-yl]benzoic acid	OC(=O)C1=CC=C(C=C1)C1=NC(C2=CC=CC(=C2)[N+]([O-])=O)=C2N=CC=CC2=C1
PDE4B	DB01151	phosphodiesterase 4B, cAMP-specific	approved	Desipramine	CNCCCN1C2=CC=CC=C2CCC2=CC=CC=C12
PDE4B	DB00472	phosphodiesterase 4B, cAMP-specific	approved	Fluoxetine	CNCCC(OC1=CC=C(C=C1)C(F)(F)F)C1=CC=CC=C1
PDE4C	DB00651	phosphodiesterase 4C, cAMP-specific	approved	Dyphylline	CN1C2=C(N(CC(O)CO)C=N2)C(=O)N(C)C1=O
PDE4C	DB00920	phosphodiesterase 4C, cAMP-specific	approved	Ketotifen	CN1CCC(CC1)=C1C2=C(SC=C2)C(=O)CC2=CC=CC=C12
PDE4C	DB01088	phosphodiesterase 4C, cAMP-specific	approved; investigational	Iloprost	CC#CCC(C)C(O)\C=C\C1C(O)CC2C\C(CC12)=C\CCCC(=O)OCC(=O)C1=CC=CC=C1
PDE4C	DB01791	phosphodiesterase 4C, cAMP-specific	experimental	Piclamilast	COC1=CC=C(C=C1OC1CCCC1)C(=O)NC1=C(Cl)C=NC=C1Cl
PDE4C	DB05266	phosphodiesterase 4C, cAMP-specific	approved; investigational	Ibudilast	CC(C)C(=O)C1=C2C=CC=CN2N=C1C(C)C
PDE4C	DB01151	phosphodiesterase 4C, cAMP-specific	approved	Desipramine	CNCCCN1C2=CC=CC=C2CCC2=CC=CC=C12
PDE4C	DB00472	phosphodiesterase 4C, cAMP-specific	approved	Fluoxetine	CNCCC(OC1=CC=C(C=C1)C(F)(F)F)C1=CC=CC=C1
PDE4D	DB00131	phosphodiesterase 4D, cAMP-specific	approved; nutraceutical	Adenosine monophosphate	NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PDE4D	DB00651	phosphodiesterase 4D, cAMP-specific	approved	Dyphylline	CN1C2=C(N(CC(O)CO)C=N2)C(=O)N(C)C1=O
PDE4D	DB00920	phosphodiesterase 4D, cAMP-specific	approved	Ketotifen	CN1CCC(CC1)=C1C2=C(SC=C2)C(=O)CC2=CC=CC=C12
PDE4D	DB01088	phosphodiesterase 4D, cAMP-specific	approved; investigational	Iloprost	CC#CCC(C)C(O)\C=C\C1C(O)CC2C\C(CC12)=C\CCCC(=O)OCC(=O)C1=CC=CC=C1
PDE4D	DB01791	phosphodiesterase 4D, cAMP-specific	experimental	Piclamilast	COC1=CC=C(C=C1OC1CCCC1)C(=O)NC1=C(Cl)C=NC=C1Cl
PDE4D	DB01954	phosphodiesterase 4D, cAMP-specific	experimental	4-[3-(Cyclopentyloxy)-4-Methoxyphenyl]-2-Pyrrolidinone	COC1=C(OC2CCCC2)C=C(C=C1)[C@@H]1CNC(=O)C1
PDE4D	DB01959	phosphodiesterase 4D, cAMP-specific	experimental	3,5-Dimethyl-1-(3-Nitrophenyl)-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester	CCOC(=O)C1=C(C)N(N=C1C)C1=CC(=CC=C1)[N+]([O-])=O
PDE4D	DB02676	phosphodiesterase 4D, cAMP-specific	experimental	2-[3-(2-Hydroxy-1,1-Dihydroxymethyl-Ethylamino)-Propylamino]-2-Hydroxymethyl-Propane-1,3-Diol	OCC(CO)(CO)NCCCNC(CO)(CO)CO
PDE4D	DB02918	phosphodiesterase 4D, cAMP-specific	experimental	6-(4-Difluoromethoxy-3-Methoxy-Phenyl)-2h-Pyridazin-3-One	COC1=C(OC(F)F)C=CC(=C1)C1=NNC(=O)C=C1
PDE4D	DB03183	phosphodiesterase 4D, cAMP-specific	experimental	1-(4-Aminophenyl)-3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester	CCOC(=O)C1=C(C)N(N=C1C)C1=CC=C(N)C=C1
PDE4D	DB03606	phosphodiesterase 4D, cAMP-specific	experimental	(S)-Rolipram	COC1=CC=C(C=C1OC1CCCC1)[C@@H]1CNC(=O)C1
PDE4D	DB03849	phosphodiesterase 4D, cAMP-specific	experimental	Cis-4-Cyano-4-[3-(Cyclopentyloxy)-4-Methoxyphenyl]Cyclohexanecarboxylic Acid	COC1=CC=C(C=C1OC1CCCC1)[C@@]1(CC[C@@H](CC1)C(O)=O)C#N
PDE4D	DB04149	phosphodiesterase 4D, cAMP-specific	experimental	(R)-Rolipram	COC1=CC=C(C=C1OC1CCCC1)[C@@H]1CNC(=O)C1
PDE4D	DB04271	phosphodiesterase 4D, cAMP-specific	experimental	3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester	CCOC(=O)C1=C(C)NN=C1C
PDE4D	DB04469	phosphodiesterase 4D, cAMP-specific	experimental	1-(4-Methoxyphenyl)-3,5-Dimethyl-1h-Pyrazole-4-Carboxylic Acid Ethyl Ester	CCOC(=O)C1=C(C)N(N=C1C)C1=CC=C(OC)C=C1
PDE4D	DB05266	phosphodiesterase 4D, cAMP-specific	approved; investigational	Ibudilast	CC(C)C(=O)C1=C2C=CC=CN2N=C1C(C)C
PDE4D	DB06842	phosphodiesterase 4D, cAMP-specific	experimental	(4R)-4-(3-butoxy-4-methoxybenzyl)imidazolidin-2-one	CCCCOC1=C(OC)C=CC(C[C@@H]2CNC(=O)N2)=C1
PDE4D	DB07051	phosphodiesterase 4D, cAMP-specific	experimental	3,5-DIMETHYL-1-PHENYL-1H-PYRAZOLE-4-CARBOXYLIC ACID ETHYL ESTER	CCOC(=O)C1=C(C)N([NH+]=C1C)C1=CC=CC=C1
PDE4D	DB07954	phosphodiesterase 4D, cAMP-specific	experimental	3-ISOBUTYL-1-METHYLXANTHINE	CC(C)CN1C2=C(N=CN2)C(=O)N(C)C1=O
PDE4D	DB08299	phosphodiesterase 4D, cAMP-specific	experimental	4-[8-(3-nitrophenyl)-1,7-naphthyridin-6-yl]benzoic acid	OC(=O)C1=CC=C(C=C1)C1=NC(C2=CC=CC(=C2)[N+]([O-])=O)=C2N=CC=CC2=C1
PDE4D	DB01151	phosphodiesterase 4D, cAMP-specific	approved	Desipramine	CNCCCN1C2=CC=CC=C2CCC2=CC=CC=C12
PDE4D	DB00472	phosphodiesterase 4D, cAMP-specific	approved	Fluoxetine	CNCCC(OC1=CC=C(C=C1)C(F)(F)F)C1=CC=CC=C1
PDE4D	DB00465	phosphodiesterase 4D, cAMP-specific	approved	Ketorolac	OC(=O)C1CCN2C1=CC=C2C(=O)C1=CC=CC=C1
PDE4D	DB00533	phosphodiesterase 4D, cAMP-specific	withdrawn; investigational	Rofecoxib	CS(=O)(=O)C1=CC=C(C=C1)C1=C(C(=O)OC1)C1=CC=CC=C1
PDE5A	DB00203	phosphodiesterase 5A, cGMP-specific	approved; investigational	Sildenafil	CCCC1=NN(C)C2=C1NC(=NC2=O)C1=C(OCC)C=CC(=C1)S(=O)(=O)N1CCN(C)CC1
PDE5A	DB00277	phosphodiesterase 5A, cGMP-specific	approved	Theophylline	CN1C2=C(NC=N2)C(=O)N(C)C1=O
PDE5A	DB00806	phosphodiesterase 5A, cGMP-specific	approved; investigational	Pentoxifylline	CN1C=NC2=C1C(=O)N(CCCCC(C)=O)C(=O)N2C
PDE5A	DB00820	phosphodiesterase 5A, cGMP-specific	approved; investigational	Tadalafil	CN1CC(=O)N2[C@H](CC3=C(NC4=CC=CC=C34)[C@H]2C2=CC3=C(OCO3)C=C2)C1=O
PDE5A	DB00862	phosphodiesterase 5A, cGMP-specific	approved	Vardenafil	CCCC1=NC(C)=C2N1NC(=NC2=O)C1=C(OCC)C=CC(=C1)S(=O)(=O)N1CCN(CC)CC1
PDE5A	DB00975	phosphodiesterase 5A, cGMP-specific	approved	Dipyridamole	OCCN(CCO)C1=NC2=C(N=C(N=C2N2CCCCC2)N(CCO)CCO)C(=N1)N1CCCCC1
PDE5A	DB01972	phosphodiesterase 5A, cGMP-specific	experimental	Guanosine-5'-Monophosphate	NC1=NC2=C(N=CN2[C@@H]2O[C@@H](COP(O)(O)=O)[C@H](O)[C@H]2O)C(=O)N1
PDE5A	DB03597	phosphodiesterase 5A, cGMP-specific	experimental	Gamma-Glutamyl[S-(2-Iodobenzyl)Cysteinyl]Glycine	N[C@@H](CCC(=O)N[C@H](CSCC1=CC=CC=C1I)C(=O)NCC(O)=O)C(O)=O
PDE5A	DB04272	phosphodiesterase 5A, cGMP-specific	experimental	Citric Acid	OC(=O)CC(O)(CC(O)=O)C(O)=O
PDE5A	DB06267	phosphodiesterase 5A, cGMP-specific	approved; investigational	Udenafil	CCCOC1=C(C=C(C=C1)S(=O)(=O)NCCC1CCCN1C)C1=NC(=O)C2=C(N1)C(CCC)=NN2C
PDE5A	DB07954	phosphodiesterase 5A, cGMP-specific	experimental	3-ISOBUTYL-1-METHYLXANTHINE	CC(C)CN1C2=C(N=CN2)C(=O)N(C)C1=O
PDE5A	DB08729	phosphodiesterase 5A, cGMP-specific	experimental	5-ethoxy-4-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)thiophene-2-sulfonamide	CCCC1=NN(C)C2=C1N=C(NC2=O)C1=C(OCC)SC(=C1)S(N)(=O)=O
PDE5A	DB01151	phosphodiesterase 5A, cGMP-specific	approved	Desipramine	CNCCCN1C2=CC=CC=C2CCC2=CC=CC=C12
PDE5A	DB00472	phosphodiesterase 5A, cGMP-specific	approved	Fluoxetine	CNCCC(OC1=CC=C(C=C1)C(F)(F)F)C1=CC=CC=C1
PDE6A	DB00472	phosphodiesterase 6A, cGMP-specific, rod, alpha	approved	Fluoxetine	CNCCC(OC1=CC=C(C=C1)C(F)(F)F)C1=CC=CC=C1
PDE6C	DB01151	phosphodiesterase 6C, cGMP-specific, cone, alpha prime	approved	Desipramine	CNCCCN1C2=CC=CC=C2CCC2=CC=CC=C12
PDE6C	DB00472	phosphodiesterase 6C, cGMP-specific, cone, alpha prime	approved	Fluoxetine	CNCCC(OC1=CC=C(C=C1)C(F)(F)F)C1=CC=CC=C1
PDE6D	DB01151	phosphodiesterase 6D, cGMP-specific, rod, delta	approved	Desipramine	CNCCCN1C2=CC=CC=C2CCC2=CC=CC=C12
PDE6D	DB00472	phosphodiesterase 6D, cGMP-specific, rod, delta	approved	Fluoxetine	CNCCC(OC1=CC=C(C=C1)C(F)(F)F)C1=CC=CC=C1
PDE6G	DB00203	phosphodiesterase 6G, cGMP-specific, rod, gamma	approved; investigational	Sildenafil	CCCC1=NN(C)C2=C1NC(=NC2=O)C1=C(OCC)C=CC(=C1)S(=O)(=O)N1CCN(C)CC1
PDE6G	DB00862	phosphodiesterase 6G, cGMP-specific, rod, gamma	approved	Vardenafil	CCCC1=NC(C)=C2N1NC(=NC2=O)C1=C(OCC)C=CC(=C1)S(=O)(=O)N1CCN(CC)CC1
PDE6G	DB07954	phosphodiesterase 6G, cGMP-specific, rod, gamma	experimental	3-ISOBUTYL-1-METHYLXANTHINE	CC(C)CN1C2=C(N=CN2)C(=O)N(C)C1=O
PDE6G	DB01151	phosphodiesterase 6G, cGMP-specific, rod, gamma	approved	Desipramine	CNCCCN1C2=CC=CC=C2CCC2=CC=CC=C12
PDE6G	DB00472	phosphodiesterase 6G, cGMP-specific, rod, gamma	approved	Fluoxetine	CNCCC(OC1=CC=C(C=C1)C(F)(F)F)C1=CC=CC=C1
PDE6H	DB00203	phosphodiesterase 6H, cGMP-specific, cone, gamma	approved; investigational	Sildenafil	CCCC1=NN(C)C2=C1NC(=NC2=O)C1=C(OCC)C=CC(=C1)S(=O)(=O)N1CCN(C)CC1
PDE6H	DB00862	phosphodiesterase 6H, cGMP-specific, cone, gamma	approved	Vardenafil	CCCC1=NC(C)=C2N1NC(=NC2=O)C1=C(OCC)C=CC(=C1)S(=O)(=O)N1CCN(CC)CC1
PDE7A	DB00651	phosphodiesterase 7A	approved	Dyphylline	CN1C2=C(N(CC(O)CO)C=N2)C(=O)N(C)C1=O
PDE7A	DB00920	phosphodiesterase 7A	approved	Ketotifen	CN1CCC(CC1)=C1C2=C(SC=C2)C(=O)CC2=CC=CC=C12
PDE7A	DB07954	phosphodiesterase 7A	experimental	3-ISOBUTYL-1-METHYLXANTHINE	CC(C)CN1C2=C(N=CN2)C(=O)N(C)C1=O
PDE7A	DB08602	phosphodiesterase 7A	experimental	3-(2,6-difluorophenyl)-2-(methylthio)quinazolin-4(3H)-one	CSC1=NC2=CC=CC=C2C(=O)N1C1=C(F)C=CC=C1F
PDE7A	DB01151	phosphodiesterase 7A	approved	Desipramine	CNCCCN1C2=CC=CC=C2CCC2=CC=CC=C12
PDE7A	DB00472	phosphodiesterase 7A	approved	Fluoxetine	CNCCC(OC1=CC=C(C=C1)C(F)(F)F)C1=CC=CC=C1
PDE7B	DB00651	phosphodiesterase 7B	approved	Dyphylline	CN1C2=C(N(CC(O)CO)C=N2)C(=O)N(C)C1=O
PDE7B	DB00920	phosphodiesterase 7B	approved	Ketotifen	CN1CCC(CC1)=C1C2=C(SC=C2)C(=O)CC2=CC=CC=C12
PDE7B	DB01151	phosphodiesterase 7B	approved	Desipramine	CNCCCN1C2=CC=CC=C2CCC2=CC=CC=C12
PDE7B	DB00472	phosphodiesterase 7B	approved	Fluoxetine	CNCCC(OC1=CC=C(C=C1)C(F)(F)F)C1=CC=CC=C1
PDE8A	DB00920	phosphodiesterase 8A	approved	Ketotifen	CN1CCC(CC1)=C1C2=C(SC=C2)C(=O)CC2=CC=CC=C12
PDE8A	DB07954	phosphodiesterase 8A	experimental	3-ISOBUTYL-1-METHYLXANTHINE	CC(C)CN1C2=C(N=CN2)C(=O)N(C)C1=O
PDE8A	DB01151	phosphodiesterase 8A	approved	Desipramine	CNCCCN1C2=CC=CC=C2CCC2=CC=CC=C12
PDE8A	DB00472	phosphodiesterase 8A	approved	Fluoxetine	CNCCC(OC1=CC=C(C=C1)C(F)(F)F)C1=CC=CC=C1
PDE8B	DB00920	phosphodiesterase 8B	approved	Ketotifen	CN1CCC(CC1)=C1C2=C(SC=C2)C(=O)CC2=CC=CC=C12
PDE8B	DB00472	phosphodiesterase 8B	approved	Fluoxetine	CNCCC(OC1=CC=C(C=C1)C(F)(F)F)C1=CC=CC=C1
PDE9A	DB03597	phosphodiesterase 9A	experimental	Gamma-Glutamyl[S-(2-Iodobenzyl)Cysteinyl]Glycine	N[C@@H](CCC(=O)N[C@H](CSCC1=CC=CC=C1I)C(=O)NCC(O)=O)C(O)=O
PDE9A	DB07954	phosphodiesterase 9A	experimental	3-ISOBUTYL-1-METHYLXANTHINE	CC(C)CN1C2=C(N=CN2)C(=O)N(C)C1=O
PDHA1	DB00157	pyruvate dehydrogenase (lipoamide) alpha 1	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
PDHA2	DB00157	pyruvate dehydrogenase (lipoamide) alpha 2	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
PDHB	DB00119	pyruvate dehydrogenase (lipoamide) beta	approved; nutraceutical	Pyruvic acid	CC(=O)C(O)=O
PDHB	DB00157	pyruvate dehydrogenase (lipoamide) beta	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
PDHX	DB04284	pyruvate dehydrogenase complex, component X	experimental	Proline Betaine	C[N+]1(C)CCC[C@@H]1C(O)=O
PDHX	DB04455	pyruvate dehydrogenase complex, component X	experimental	Trimethyl Glycine	C[N+](C)(C)CC(O)=O
PDK1	DB07403	pyruvate dehydrogenase kinase, isozyme 1	experimental	4-[(3-CHLORO-4-{[(2R)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANOYL]AMINO}PHENYL)SULFONYL]-N,N-DIMETHYLBENZAMIDE	CN(C)C(=O)C1=CC=C(C=C1)S(=O)(=O)C1=CC=C(NC(=O)[C@@](C)(O)C(F)(F)F)C(Cl)=C1
PDK1	DB08809	pyruvate dehydrogenase kinase, isozyme 1	experimental	Dichloroacetic Acid	OC(=O)C(Cl)Cl
PDK1	DB00482	pyruvate dehydrogenase kinase, isozyme 1	approved; investigational	Celecoxib	CC1=CC=C(C=C1)C1=CC(=NN1C1=CC=C(C=C1)S(N)(=O)=O)C(F)(F)F
PDK2	DB03431	pyruvate dehydrogenase kinase, isozyme 2	experimental	Adenosine-5'-Diphosphate	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](CO[P@](O)(=O)OP(O)(O)=O)[C@H](O)[C@H]1O
PDK2	DB08608	pyruvate dehydrogenase kinase, isozyme 2	experimental	4-({(2R,5S)-2,5-DIMETHYL-4-[(2R)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANOYL]PIPERAZIN-1-YL}CARBONYL)BENZONITRILE	C[C@@H]1CN([C@@H](C)CN1C(=O)C1=CC=C(C=C1)C#N)C(=O)[C@@](C)(O)C(F)(F)F
PDK2	DB08609	pyruvate dehydrogenase kinase, isozyme 2	experimental	(N-{4-[(ETHYLANILINO)SULFONYL]-2-METHYLPHENYL}-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANAMIDE	CCN(C1=CC=CC=C1)S(=O)(=O)C1=CC(C)=C(NC(=O)[C@@](C)(O)C(F)(F)F)C=C1
PDK2	DB08610	pyruvate dehydrogenase kinase, isozyme 2	experimental	N-(2-AMINOETHYL)-2-{3-CHLORO-4-[(4-ISOPROPYLBENZYL)OXY]PHENYL} ACETAMIDE	CC(C)C1=CC=C(COC2=C(Cl)C=C(CC(=O)NCCN)C=C2)C=C1
PDK2	DB00877	pyruvate dehydrogenase kinase, isozyme 2	approved; investigational	Sirolimus	CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1O
PDK3	DB03758	pyruvate dehydrogenase kinase, isozyme 3	experimental	Radicicol	C[C@@H]1C[C@H]2O[C@@H]2CCCCC(=O)C[C@H]2[C@H](Cl)C(=O)CC(=O)[C@H]2C(=O)O1
PDK3	DB03760	pyruvate dehydrogenase kinase, isozyme 3	experimental	Dihydrolipoic Acid	OC(=O)CCCC[C@@H](S)CCS
PDK4	DB08356	pyruvate dehydrogenase kinase, isozyme 4	experimental	4-[4-(4-methoxyphenyl)-5-methyl-1H-pyrazol-3-yl]benzene-1,3-diol	COC1=CC=C(C=C1)C1=C(C)NN=C1C1=C(O)C=C(O)C=C1
PDP1	DB02494	pyruvate dehyrogenase phosphatase catalytic subunit 1	experimental	Alpha-Hydroxy-Beta-Phenyl-Propionic Acid	O[C@@H](CC1=CC=CC=C1)C(O)=O
PDP1	DB03884	pyruvate dehyrogenase phosphatase catalytic subunit 1	experimental	3-Phenylpyruvic Acid	OC(=O)C(=O)CC1=CC=CC=C1
PDXK	DB00147	pyridoxal (pyridoxine, vitamin B6) kinase	approved; nutraceutical	Pyridoxal	CC1=NC=C(CO)C(C=O)=C1O
PDXK	DB00165	pyridoxal (pyridoxine, vitamin B6) kinase	approved; nutraceutical	Pyridoxine	CC1=NC=C(CO)C(CO)=C1O
PDXK	DB03431	pyridoxal (pyridoxine, vitamin B6) kinase	experimental	Adenosine-5'-Diphosphate	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](CO[P@](O)(=O)OP(O)(O)=O)[C@H](O)[C@H]1O
PDXK	DB03909	pyridoxal (pyridoxine, vitamin B6) kinase	experimental	Adenosine-5'-[Beta, Gamma-Methylene]Triphosphate	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](CO[P@@](O)(=O)O[P@@](O)(=O)CP(O)(O)=O)[C@H](O)[C@H]1O
PDXK	DB04770	pyridoxal (pyridoxine, vitamin B6) kinase	experimental	O6-(R)-ROSCOVITINE, R-2-(6-BENZYLOXY-9-ISOPROPYL-9H-PURIN-2-YLAMINO)-BUTAN-1-OL	CC[C@H](CO)NC1=NC2=C(N=CN2C(C)C)C(OCC2=CC=CC=C2)=N1
PDXK	DB04776	pyridoxal (pyridoxine, vitamin B6) kinase	experimental	N6-METHYL-(R)-ROSCOVITINE, R-2-[6-(BENZYL-METHYL-AMINO)-9-ISOPROPYL-9H-PURIN-2-YLAMINO]-BUTAN-1-OL	CC[C@H](CO)NC1=NC2=C(N=CN2C(C)C)C(=N1)N(C)CC1=CC=CC=C1
PFAS	DB00142	phosphoribosylformylglycinamidine synthase	approved; nutraceutical	L-Glutamic Acid	N[C@@H](CCC(O)=O)C(O)=O
PFAS	DB03431	phosphoribosylformylglycinamidine synthase	experimental	Adenosine-5'-Diphosphate	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](CO[P@](O)(=O)OP(O)(O)=O)[C@H](O)[C@H]1O
PFAS	DB00145	phosphoribosylformylglycinamidine synthase	approved; nutraceutical	Glycine	NCC(O)=O
PFAS	DB00130	phosphoribosylformylglycinamidine synthase	approved; nutraceutical; investigational	L-Glutamine	N[C@@H](CCC(N)=O)C(O)=O
PFDN6	DB01033	prefoldin subunit 6	approved	Mercaptopurine	S=C1N=CNC2=C1NC=N2
PFDN6	DB00563	prefoldin subunit 6	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
PFKFB1	DB02393	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1	experimental	D-Gluco-2,5-Anhydro-1-Deoxy-1-Phosphonohexitol-6-Phosphate	O[C@@H]1[C@@H](O)[C@H](CP(O)(O)=O)O[C@H]1COP(O)(O)=O
PFKFB1	DB02515	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1	experimental	3-Phosphoglycerol	OC[C@@H](O)COP(O)(O)=O
PFKFB1	DB02930	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1	experimental	Phosphothiophosphoric Acid-Adenylate Ester	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](CO[P@](O)(=O)O[P@@](O)(=O)O[P@](O)(S)=O)[C@H](O)[C@H]1O
PFKFB1	DB04137	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1	experimental	Guanosine-5'-Triphosphate	NC1=NC2=C(N=CN2[C@@H]2O[C@@H](CO[P@](O)(=O)O[P@@](O)(=O)OP(O)(O)=O)[C@H](O)[C@H]2O)C(=O)N1
PFKFB1	DB04493	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1	experimental	Fructose-6-Phosphate	OC[C@]1(O)O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O
PFKFB4	DB04395	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4	experimental	Phosphoaminophosphonic Acid-Adenylate Ester	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](CO[P@](O)(=O)O[P@@](O)(=O)NP(O)(O)=O)[C@H](O)[C@H]1O
PFKFB4	DB04493	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4	experimental	Fructose-6-Phosphate	OC[C@]1(O)O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O
PFKFB4	DB00515	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4	approved	Cisplatin	N[Pt](N)(Cl)Cl
PFKM	DB02726	phosphofructokinase, muscle	experimental	2-Phosphoglycolic Acid	OC(=O)COP(O)(O)=O
PFKM	DB04493	phosphofructokinase, muscle	experimental	Fructose-6-Phosphate	OC[C@]1(O)O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O
PGD	DB00789	phosphogluconate dehydrogenase	approved	Gadopentetate dimeglumine	[Gd+3].CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.OC(=O)CN(CCN(CCN(CC(O)=O)CC([O-])=O)CC([O-])=O)CC([O-])=O
PGD	DB00851	phosphogluconate dehydrogenase	approved	Dacarbazine	CN(C)\N=N\C1=C(N=CN1)C(N)=O
PGD	DB00920	phosphogluconate dehydrogenase	approved	Ketotifen	CN1CCC(CC1)=C1C2=C(SC=C2)C(=O)CC2=CC=CC=C12
PGD	DB02076	phosphogluconate dehydrogenase	experimental	6-Phosphogluconic Acid	O[C@H](COP(O)(O)=O)[C@H](O)[C@H](O)[C@@H](O)C(O)=O
PGD	DB02212	phosphogluconate dehydrogenase	experimental	Pyrophosphate 2-	O[P@]([O-])(=O)O[P@@](O)([O-])=O
PGD	DB03962	phosphogluconate dehydrogenase	experimental	Nicotinamide 8-Bromo-Adenine Dinucleotide Phosphate	NC(=O)C1=CC=C[N+](=C1)[C@@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@@H]2O[C@H]([C@H](OP(O)(O)=O)[C@H]2O)N2C(Br)=NC3=C2N=CN=C3N)[C@H](O)[C@H]1O
PGK1	DB00709	phosphoglycerate kinase 1	approved; investigational	Lamivudine	NC1=NC(=O)N(C=C1)[C@@H]1CS[C@H](CO)O1
PGK1	DB00121	phosphoglycerate kinase 1	approved; nutraceutical	Biotin	OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12
PGM1	DB00515	phosphoglucomutase 1	approved	Cisplatin	N[Pt](N)(Cl)Cl
PHGDH	DB00157	phosphoglycerate dehydrogenase	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
PHGDH	DB01907	phosphoglycerate dehydrogenase	experimental	Nicotinamide-Adenine-Dinucleotide	NC(=O)C1=CC=C[N+](=C1)[C@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@@H]1O
PHGDH	DB01694	phosphoglycerate dehydrogenase	experimental	D-tartaric acid	O[C@@H]([C@@H](O)C(O)=O)C(O)=O
PHOSPHO1	DB00122	phosphatase, orphan 1	approved; nutraceutical	Choline	C[N+](C)(C)CCO
PHYH	DB00126	phytanoyl-CoA 2-hydroxylase	approved; nutraceutical	Vitamin C	OC[C@H](O)[C@H]1OC(=O)C(O)=C1O
PIGA	DB03014	phosphatidylinositol glycan anchor biosynthesis, class A	experimental	Heme	CC1=C(CCC(O)=O)C2=CC3=[N+]4C(=CC5=C(C=C)C(C)=C6C=C7C(C=C)=C(C)C8=[N+]7[Fe@]4(N2C1=C8)N56)C(C)=C3CCC(O)=O
PIK3C2B	DB00619	phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta	approved	Imatinib	CN1CCN(CC2=CC=C(C=C2)C(=O)NC2=CC(NC3=NC=CC(=N3)C3=CN=CC=C3)=C(C)C=C2)CC1
PIK3C3	DB06836	phosphatidylinositol 3-kinase, catalytic subunit type 3	experimental	N-(5-(4-CHLORO-3-(2-HYDROXY-ETHYLSULFAMOYL)- PHENYLTHIAZOLE-2-YL)-ACETAMIDE	CC(=O)\N=C1\NC(C)=C(S1)C1=CC(=C(Cl)C=C1)S(=O)(=O)NCCO
PIK3CA	DB08059	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha	experimental	(1S,6BR,9AS,11R,11BR)-9A,11B-DIMETHYL-1-[(METHYLOXY)METHYL]-3,6,9-TRIOXO-1,6,6B,7,8,9,9A,10,11,11B-DECAHYDRO-3H-FURO[4,3,2-DE]INDENO[4,5-H][2]BENZOPYRAN-11-YL ACETATE	COC[C@H]1OC(=O)C2=COC3=C2[C@@]1(C)C1=C([C@@H]2CCC(=O)[C@@]2(C)C[C@H]1OC(C)=O)C3=O
PIK3CA	DB01248	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha	approved; investigational	Docetaxel	CC(=O)O[C@@]12CO[C@@H]1C[C@H](O)[C@]1(C)[C@@H]2[C@H](OC(=O)C2=CC=CC=C2)[C@]2(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C3=CC=CC=C3)C(C)=C([C@@H](O)C1=O)C2(C)C
PIK3CA	DB00171	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PIK3CA	DB00877	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha	approved; investigational	Sirolimus	CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1O
PIK3CA	DB00122	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha	approved; nutraceutical	Choline	C[N+](C)(C)CCO
PIK3CA	DB00394	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha	approved	Beclomethasone	C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
PIK3CA	DB00443	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha	approved	Betamethasone	C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
PIK3CA	DB01222	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha	approved; investigational	Budesonide	CCC[C@H]1O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO
PIK3CA	DB01410	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha	approved; investigational	Ciclesonide	CC(C)C(=O)OCC(=O)[C@@]12OC(O[C@@H]1C[C@H]1[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@]21C)C1CCCCC1
PIK3CA	DB01260	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha	approved; investigational	Desonide	CC1(C)O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO
PIK3CA	DB01234	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha	approved; investigational	Dexamethasone	C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
PIK3CA	DB00180	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha	approved; investigational	Flunisolide	CC1(C)O[C@@H]2C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO
PIK3CA	DB00588	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha	approved; investigational	Fluticasone Propionate	CCC(=O)O[C@@]1([C@H](C)C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)C(=O)SCF
PIK3CA	DB00741	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha	approved	Hydrocortisone	C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
PIK3CA	DB00959	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha	approved	Methylprednisolone	C[C@H]1C[C@H]2[C@@H]3CC[C@](O)(C(=O)CO)[C@@]3(C)C[C@H](O)[C@@H]2[C@@]2(C)C=CC(=O)C=C12
PIK3CA	DB00764	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha	approved	Mometasone	C[C@@H]1C[C@H]2C3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CCl
PIK3CA	DB01384	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha	approved	Paramethasone	C[C@@H]1C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
PIK3CA	DB00860	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha	approved	Prednisolone	C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
PIK3CA	DB00635	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha	approved	Prednisone	C[C@]12CC(=O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
PIK3CA	DB00896	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha	approved	Rimexolone	CCC(=O)[C@@]1(C)[C@H](C)CC2C3CCC4=CC(=O)C=C[C@]4(C)C3[C@@H](O)C[C@]12C
PIK3CA	DB00620	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha	approved	Triamcinolone	C[C@]12C[C@H](O)[C@@]3(F)[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1C[C@@H](O)[C@]2(O)C(=O)CO
PIK3CA	DB00131	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha	approved; nutraceutical	Adenosine monophosphate	NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PIK3CA	DB00125	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
PIK3CA	DB00155	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha	approved; nutraceutical	L-Citrulline	N[C@@H](CCCNC(N)=O)C(O)=O
PIK3CA	DB00435	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha	approved	Nitric Oxide	[N]=O
PIK3CA	DB00864	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha	approved; investigational	Tacrolimus	CO[C@@H]1C[C@@H](CC[C@H]1O)\C=C(/C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H]([C@H](C[C@H]2C)OC)[C@H](C[C@@H](C)C\C(C)=C\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]1C)OC
PIK3CA	DB00619	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha	approved	Imatinib	CN1CCN(CC2=CC=C(C=C2)C(=O)NC2=CC(NC3=NC=CC(=N3)C3=CN=CC=C3)=C(C)C=C2)CC1
PIK3CD	DB06831	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	experimental	2-((9H-PURIN-6-YLTHIO)METHYL)-5-CHLORO-3-(2-METHOXYPHENYL)QUINAZOLIN-4(3H)-ONE	COC1=CC=CC=C1N1C(=O)C2=C(Cl)C=CC=C2N=C1CSC1=C2N=CNC2=NC=N1
PIK3CG	DB02010	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma	experimental	Staurosporine	CN[C@@H]1C[C@@H]2O[C@](C)([C@@H]1OC)N1C3=C(C=CC=C3)C3=C1C1=C(C4=C(C=CC=C4)N21)C1=C3CNC1=O
PIK3CG	DB02375	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma	experimental	Myricetin	OC1=CC(O)=C2C(OC(=C(O)C2=O)C2=CC(O)=C(O)C(O)=C2)=C1
PIK3CG	DB02656	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma	experimental	2-(4-Morpholinyl)-8-Phenyl-4h-1-Benzopyran-4-One	O=C1C=C(OC2=C1C=CC=C2C1=CC=CC=C1)N1CCOCC1
PIK3CG	DB04216	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma	experimental	Quercetin	OC1=CC2=C(C(O)=C1)C(=O)C(O)=C(O2)C1=CC=C(O)C(O)=C1
PIK3CG	DB04769	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma	experimental	5-QUINOXALIN-6-YLMETHYLENE-THIAZOLIDINE-2,4-DIONE	O=C1NC(=O)\C(S1)=C\C1=CC2=C(C=C1)N=CC=N2
PIK3CG	DB06831	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma	experimental	2-((9H-PURIN-6-YLTHIO)METHYL)-5-CHLORO-3-(2-METHOXYPHENYL)QUINAZOLIN-4(3H)-ONE	COC1=CC=CC=C1N1C(=O)C2=C(Cl)C=CC=C2N=C1CSC1=C2N=CNC2=NC=N1
PIK3CG	DB06836	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma	experimental	N-(5-(4-CHLORO-3-(2-HYDROXY-ETHYLSULFAMOYL)- PHENYLTHIAZOLE-2-YL)-ACETAMIDE	CC(=O)\N=C1\NC(C)=C(S1)C1=CC(=C(Cl)C=C1)S(=O)(=O)NCCO
PIK3CG	DB07073	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma	experimental	5,5-dimethyl-2-morpholin-4-yl-5,6-dihydro-1,3-benzothiazol-7(4H)-one	CC1(C)CC2=C(SC(=N2)N2CCOCC2)C(=O)C1
PIK3CG	DB07335	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma	experimental	3-[4-AMINO-1-(1-METHYLETHYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL]PHENOL	CC(C)N1N=C(C2=C1N=CN=C2N)C1=CC=CC(O)=C1
PIK3CG	DB07503	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma	experimental	(5E)-5-[(2,2-DIFLUORO-1,3-BENZODIOXOL-5-YL)METHYLENE]-1,3-THIAZOLIDINE-2,4-DIONE	FC1(F)OC2=C(O1)C=C(\C=C1/SC(=O)NC1=O)C=C2
PIK3CG	DB08059	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma	experimental	(1S,6BR,9AS,11R,11BR)-9A,11B-DIMETHYL-1-[(METHYLOXY)METHYL]-3,6,9-TRIOXO-1,6,6B,7,8,9,9A,10,11,11B-DECAHYDRO-3H-FURO[4,3,2-DE]INDENO[4,5-H][2]BENZOPYRAN-11-YL ACETATE	COC[C@H]1OC(=O)C2=COC3=C2[C@@]1(C)C1=C([C@@H]2CCC(=O)[C@@]2(C)C[C@H]1OC(C)=O)C3=O
PIK3CG	DB08300	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma	experimental	1-methyl-3-naphthalen-2-yl-1H-pyrazolo[3,4-d]pyrimidin-4-amine	CN1N=C(C2=C(N)N=CN=C12)C1=CC2=CC=CC=C2C=C1
PIK3R1	DB01064	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	approved	Isoproterenol	CC(C)NCC(O)C1=CC(O)=C(O)C=C1
PIK3R1	DB08059	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	experimental	(1S,6BR,9AS,11R,11BR)-9A,11B-DIMETHYL-1-[(METHYLOXY)METHYL]-3,6,9-TRIOXO-1,6,6B,7,8,9,9A,10,11,11B-DECAHYDRO-3H-FURO[4,3,2-DE]INDENO[4,5-H][2]BENZOPYRAN-11-YL ACETATE	COC[C@H]1OC(=O)C2=COC3=C2[C@@]1(C)C1=C([C@@H]2CCC(=O)[C@@]2(C)C[C@H]1OC(C)=O)C3=O
PIK3R1	DB00171	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PIK3R1	DB00877	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	approved; investigational	Sirolimus	CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1O
PIK3R1	DB00122	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	approved; nutraceutical	Choline	C[N+](C)(C)CCO
PIK3R1	DB00394	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	approved	Beclomethasone	C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
PIK3R1	DB00443	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	approved	Betamethasone	C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
PIK3R1	DB01222	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	approved; investigational	Budesonide	CCC[C@H]1O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO
PIK3R1	DB01410	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	approved; investigational	Ciclesonide	CC(C)C(=O)OCC(=O)[C@@]12OC(O[C@@H]1C[C@H]1[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@]21C)C1CCCCC1
PIK3R1	DB01260	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	approved; investigational	Desonide	CC1(C)O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO
PIK3R1	DB01234	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	approved; investigational	Dexamethasone	C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
PIK3R1	DB00180	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	approved; investigational	Flunisolide	CC1(C)O[C@@H]2C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO
PIK3R1	DB00588	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	approved; investigational	Fluticasone Propionate	CCC(=O)O[C@@]1([C@H](C)C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)C(=O)SCF
PIK3R1	DB00741	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	approved	Hydrocortisone	C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
PIK3R1	DB00959	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	approved	Methylprednisolone	C[C@H]1C[C@H]2[C@@H]3CC[C@](O)(C(=O)CO)[C@@]3(C)C[C@H](O)[C@@H]2[C@@]2(C)C=CC(=O)C=C12
PIK3R1	DB00764	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	approved	Mometasone	C[C@@H]1C[C@H]2C3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CCl
PIK3R1	DB01384	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	approved	Paramethasone	C[C@@H]1C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
PIK3R1	DB00860	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	approved	Prednisolone	C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
PIK3R1	DB00635	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	approved	Prednisone	C[C@]12CC(=O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
PIK3R1	DB00896	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	approved	Rimexolone	CCC(=O)[C@@]1(C)[C@H](C)CC2C3CCC4=CC(=O)C=C[C@]4(C)C3[C@@H](O)C[C@]12C
PIK3R1	DB00620	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	approved	Triamcinolone	C[C@]12C[C@H](O)[C@@]3(F)[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1C[C@@H](O)[C@]2(O)C(=O)CO
PIK3R1	DB00131	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	approved; nutraceutical	Adenosine monophosphate	NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PIK3R1	DB00125	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
PIK3R1	DB00155	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	approved; nutraceutical	L-Citrulline	N[C@@H](CCCNC(N)=O)C(O)=O
PIK3R1	DB00435	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	approved	Nitric Oxide	[N]=O
PIK3R1	DB00864	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	approved; investigational	Tacrolimus	CO[C@@H]1C[C@@H](CC[C@H]1O)\C=C(/C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H]([C@H](C[C@H]2C)OC)[C@H](C[C@@H](C)C\C(C)=C\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]1C)OC
PIK3R1	DB00619	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	approved	Imatinib	CN1CCN(CC2=CC=C(C=C2)C(=O)NC2=CC(NC3=NC=CC(=N3)C3=CN=CC=C3)=C(C)C=C2)CC1
PIK3R2	DB01064	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	approved	Isoproterenol	CC(C)NCC(O)C1=CC(O)=C(O)C=C1
PIK3R3	DB01064	phosphoinositide-3-kinase, regulatory subunit 3 (gamma)	approved	Isoproterenol	CC(C)NCC(O)C1=CC(O)=C(O)C=C1
PIP5K1A	DB00122	phosphatidylinositol-4-phosphate 5-kinase, type I, alpha	approved; nutraceutical	Choline	C[N+](C)(C)CCO
PIP5K1C	DB00122	phosphatidylinositol-4-phosphate 5-kinase, type I, gamma	approved; nutraceutical	Choline	C[N+](C)(C)CCO
PIPOX	DB00145	pipecolic acid oxidase	approved; nutraceutical	Glycine	NCC(O)=O
PISD	DB00144	phosphatidylserine decarboxylase	approved; nutraceutical	Phosphatidylserine	CCCC(=O)O[C@H](COC(=O)CC)COP(O)(=O)OC[C@H](N)C(O)=O
PKLR	DB00119	pyruvate kinase, liver and RBC	approved; nutraceutical	Pyruvic acid	CC(=O)C(O)=O
PKLR	DB02726	pyruvate kinase, liver and RBC	experimental	2-Phosphoglycolic Acid	OC(=O)COP(O)(O)=O
PKLR	DB04551	pyruvate kinase, liver and RBC	experimental	Fructose-1,6-Diphosphate	O[C@@H]1[C@@H](O)[C@@](O)(COP(O)(O)=O)O[C@@H]1COP(O)(O)=O
PKLR	DB00131	pyruvate kinase, liver and RBC	approved; nutraceutical	Adenosine monophosphate	NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PKLR	DB00171	pyruvate kinase, liver and RBC	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PKLR	DB00630	pyruvate kinase, liver and RBC	approved	Alendronate	NCCCC(O)(P(O)(O)=O)P(O)(O)=O
PKLR	DB00710	pyruvate kinase, liver and RBC	approved; investigational	Ibandronate	CCCCCN(C)CCC(O)(P(O)(O)=O)P(O)(O)=O
PKLR	DB00282	pyruvate kinase, liver and RBC	approved	Pamidronate	NCCC(O)(P(O)(O)=O)P(O)(O)=O
PKLR	DB00884	pyruvate kinase, liver and RBC	approved; investigational	Risedronate	OC(CC1=CN=CC=C1)(P(O)(O)=O)P(O)(O)=O
PKLR	DB00399	pyruvate kinase, liver and RBC	approved	Zoledronate	OC(CN1C=CN=C1)(P(O)(O)=O)P(O)(O)=O
PLA2G15	DB01992	phospholipase A2, group XV	experimental	Coenzyme A	CC(C)(CO[P@](O)(=O)O[P@@](O)(=O)OC[C@@H]1O[C@H]([C@H](O)[C@H]1OP(O)(O)=O)N1C=NC2=C1N=CN=C2N)[C@@H](O)C(=O)NCCC(=O)NCCS
PLA2G15	DB03230	phospholipase A2, group XV	experimental	Adenosine-5'-Propylphosphate	CCCO[P@@](O)(=O)OC[C@@H]1O[C@H]([C@H](O)[C@H]1O)N1C=NC2=C1N=CN=C2N
PLA2G1B	DB02210	phospholipase A2, group IB (pancreas)	experimental	Hexane-1,6-Diol	OCCCCCCO
PLA2G1B	DB02448	phospholipase A2, group IB (pancreas)	experimental	N-Tridecanoic Acid	CCCCCCCCCCCCC(O)=O
PLA2G1B	DB02659	phospholipase A2, group IB (pancreas)	experimental	Cholic Acid	C[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C
PLA2G1B	DB02795	phospholipase A2, group IB (pancreas)	experimental	P-Anisic Acid	COC1=CC=C(C=C1)C(O)=O
PLA2G1B	DB02938	phospholipase A2, group IB (pancreas)	experimental	Heptanoic Acid	CCCCCCC(O)=O
PLA2G1B	DB02944	phospholipase A2, group IB (pancreas)	experimental	Alpha-D-Mannose	OC[C@@H]1O[C@H](O)[C@@H](O)[C@H](O)[C@H]1O
PLA2G1B	DB03565	phospholipase A2, group IB (pancreas)	experimental	1-O-Octyl-2-Heptylphosphonyl-Sn-Glycero-3-Phosphoethanolamine	CCCCCCCCOC[C@@H](CO[P@](O)(=O)OCCN)O[P@@](O)(=O)CCCCCCC
PLA2G1B	DB03587	phospholipase A2, group IB (pancreas)	experimental	Pyruvoyl Group	CC(=O)C=O
PLA2G1B	DB03633	phospholipase A2, group IB (pancreas)	experimental	Lpc-Ether	CCCCCCCCCCCCCCCCCCOC[C@@H](O)CO[P@@](O)(=O)OCC[N+](C)(C)C
PLA2G1B	DB04552	phospholipase A2, group IB (pancreas)	approved	Niflumic Acid	OC(=O)C1=C(NC2=CC=CC(=C2)C(F)(F)F)N=CC=C1
PLA2G1B	DB07657	phospholipase A2, group IB (pancreas)	experimental	PHOSPHONIC ACID 2-DODECANOYLAMINO-HEXYL ESTER PROPYL ESTER	CCCCCCCCCCCC(=O)N[C@H](CCCC)CO[P@](O)(=O)OCCO
PLA2G1B	DB07836	phospholipase A2, group IB (pancreas)	experimental	1-DECYL-3-TRIFLUORO ETHYL-SN-GLYCERO-2-PHOSPHOMETHANOL	CCCCCCCCCCOC[C@@H](COCC(F)(F)F)O[P@](O)(=O)OC
PLA2G1B	DB00917	phospholipase A2, group IB (pancreas)	approved	Dinoprostone	CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O
PLA2G1B	DB01240	phospholipase A2, group IB (pancreas)	approved	Epoprostenol	CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)C[C@@H]2OC(C[C@H]12)=CCCCC(O)=O
PLA2G2A	DB00328	phospholipase A2, group IIA (platelets, synovial fluid)	approved; investigational	Indomethacin	COC1=CC2=C(C=C1)N(C(=O)C1=CC=C(Cl)C=C1)C(C)=C2CC(O)=O
PLA2G2A	DB00586	phospholipase A2, group IIA (platelets, synovial fluid)	approved	Diclofenac	OC(=O)CC1=CC=CC=C1NC1=C(Cl)C=CC=C1Cl
PLA2G2A	DB01955	phospholipase A2, group IIA (platelets, synovial fluid)	experimental	1,4-Butanediol	OCCCCO
PLA2G2A	DB02080	phospholipase A2, group IIA (platelets, synovial fluid)	experimental	1-{2-[2-(2-Methoxyethoxy)Ethoxy]Ethoxy}-4-(1,1,3,3-Tetramethylbutyl)Benzene	COCCOCCOCCOC1=CC=C(C=C1)C(C)(C)CC(C)(C)C
PLA2G2A	DB02448	phospholipase A2, group IIA (platelets, synovial fluid)	experimental	N-Tridecanoic Acid	CCCCCCCCCCCCC(O)=O
PLA2G2A	DB02504	phospholipase A2, group IIA (platelets, synovial fluid)	experimental	[3-(1-Benzyl-3-Carbamoylmethyl-2-Methyl-1h-Indol-5-Yloxy)-Propyl-]-Phosphonic Acid	CC1=C(CC(N)=O)C2=C(C=CC(OCCCP(O)(O)=O)=C2)N1CC1=CC=CC=C1
PLA2G2A	DB02936	phospholipase A2, group IIA (platelets, synovial fluid)	experimental	4-(1-Benzyl-3-Carbamoylmethyl-2-Methyl-1h-Indol-5-Yloxy)-Butyric Acid	CC1=C(CC(N)=O)C2=C(C=CC(OCCCC(O)=O)=C2)N1CC1=CC=CC=C1
PLA2G2A	DB03121	phospholipase A2, group IIA (platelets, synovial fluid)	experimental	1-Benzyl-5-Methoxy-2-Methyl-1h-Indol-3-Yl)-Acetic Acid	COC1=CC2=C(C=C1)N(CC1=CC=CC=C1)C(C)=C2CC(O)=O
PLA2G2A	DB03471	phospholipase A2, group IIA (platelets, synovial fluid)	experimental	6-Phenyl-4(R)-(7-Phenyl-Heptanoylamino)-Hexanoic Acid	OC(=O)CC[C@H](CCC1=CC=CC=C1)NC(=O)CCCCCCC1=CC=CC=C1
PLA2G2A	DB03784	phospholipase A2, group IIA (platelets, synovial fluid)	experimental	Elaidoylamide	CCCCCCCC\C=C\CCCCCCCC(N)=O
PLA2G2A	DB04112	phospholipase A2, group IIA (platelets, synovial fluid)	experimental	1-Octadecyl-2-Acetamido-2-Deoxy-Sn-Glycerol-3-Phosphoethylmethyl Sulfide	CCCCCCCCCCCCCCCCCCOC[C@@H](CO[P@](O)(=O)OCCSC)NC(C)=O
PLA2G2A	DB04287	phospholipase A2, group IIA (platelets, synovial fluid)	experimental	(S)-5-(4-Benzyloxy-Phenyl)-4-(7-Phenyl-Heptanoylamino)-Pentanoic Acid	OC(=O)CC[C@H](CC1=CC=C(OCC2=CC=CC=C2)C=C1)NC(=O)CCCCCCC1=CC=CC=C1
PLA2G2A	DB04786	phospholipase A2, group IIA (platelets, synovial fluid)	approved	Suramin	CC1=C(NC(=O)C2=CC(NC(=O)NC3=CC=CC(=C3)C(=O)NC3=C(C)C=CC(=C3)C(=O)NC3=C4C(C=C(C=C4S(O)(=O)=O)S(O)(=O)=O)=C(C=C3)S(O)(=O)=O)=CC=C2)C=C(C=C1)C(=O)NC1=C2C(C=C(C=C2S(O)(=O)=O)S(O)(=O)=O)=C(C=C1)S(O)(=O)=O
PLA2G2A	DB00435	phospholipase A2, group IIA (platelets, synovial fluid)	approved	Nitric Oxide	[N]=O
PLA2G2A	DB00482	phospholipase A2, group IIA (platelets, synovial fluid)	approved; investigational	Celecoxib	CC1=CC=C(C=C1)C1=CC(=NN1C1=CC=C(C=C1)S(N)(=O)=O)C(F)(F)F
PLA2G2E	DB00233	phospholipase A2, group IIE	approved	Aminosalicylic Acid	NC1=CC(O)=C(C=C1)C(O)=O
PLA2G2E	DB01955	phospholipase A2, group IIE	experimental	1,4-Butanediol	OCCCCO
PLA2G2E	DB02448	phospholipase A2, group IIE	experimental	N-Tridecanoic Acid	CCCCCCCCCCCCC(O)=O
PLA2G2E	DB02636	phospholipase A2, group IIE	experimental	9-Hydroxy-8-Methoxy-6-Nitro-Phenanthrol[3,4-D][1,3]Dioxole-5-Carboxylic Acid	COC1=C(O)C=CC2=C1C=C(C1=C2C2=C(OCO2)C=C1C(O)=O)[N+]([O-])=O
PLA2G2E	DB02758	phospholipase A2, group IIE	experimental	Indolylpropionic Acid	OC(=O)CCC1=CNC2=CC=CC=C12
PLA2G2E	DB02795	phospholipase A2, group IIE	experimental	P-Anisic Acid	COC1=CC=C(C=C1)C(O)=O
PLA2G2E	DB03585	phospholipase A2, group IIE	experimental; withdrawn	Oxyphenbutazone	CCCCC1C(=O)N(N(C1=O)C1=CC=C(O)C=C1)C1=CC=CC=C1
PLA2G2E	DB04077	phospholipase A2, group IIE	experimental	Glycerol	OCC(O)CO
PLA2G2E	DB04743	phospholipase A2, group IIE	experimental	Nimesulide	CS(=O)(=O)NC1=CC=C(C=C1OC1=CC=CC=C1)[N+]([O-])=O
PLA2G2E	DB06987	phospholipase A2, group IIE	experimental	2-(4-(2-HYDROXY-3-(ISOPROPYLAMINO)PROPOXY)PHENYL)ETHANAMIDE	CC(C)NC[C@@H](O)COC1=CC=C(CC(N)=O)C=C1
PLA2G2E	DB07500	phospholipase A2, group IIE	experimental	(2E)-1-[2-hydroxy-4-methoxy-5-(3-methylbut-2-en-1-yl)phenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one	COC1=CC(O)=C(C=C1CC=C(C)C)C(=O)\C=C\C1=CC=C(O)C=C1
PLA2G2E	DB07950	phospholipase A2, group IIE	experimental	1H-INDOL-3-YLACETIC ACID	OC(=O)CC1=CNC2=C1C=CC=C2
PLA2G2E	DB07958	phospholipase A2, group IIE	experimental	(2-CARBAMOYLMETHYL-5-PROPYL-OCTAHYDRO-INDOL-7-YL)ACETIC ACID	CCCC1=CC2=C(NC(CC(N)=O)=C2)C(CC(O)=O)=C1
PLA2G2E	DB08447	phospholipase A2, group IIE	experimental	3-{3-[(DIMETHYLAMINO)METHYL]-1H-INDOL-7-YL}PROPAN-1-OL	CN(C)CC1=CNC2=C1C=CC=C2CCCO
PLA2G4A	DB00588	phospholipase A2, group IVA (cytosolic, calcium-dependent)	approved; investigational	Fluticasone Propionate	CCC(=O)O[C@@]1([C@H](C)C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)C(=O)SCF
PLA2G4A	DB01103	phospholipase A2, group IVA (cytosolic, calcium-dependent)	approved	Quinacrine	CCN(CC)CCCC(C)NC1=C2C=C(OC)C=CC2=NC2=C1C=CC(Cl)=C2
PLA2G4A	DB04552	phospholipase A2, group IVA (cytosolic, calcium-dependent)	approved	Niflumic Acid	OC(=O)C1=C(NC2=CC=CC(=C2)C(F)(F)F)N=CC=C1
PLA2G4A	DB00945	phospholipase A2, group IVA (cytosolic, calcium-dependent)	approved	Acetylsalicylic acid	CC(=O)OC1=CC=CC=C1C(O)=O
PLA2G4A	DB00482	phospholipase A2, group IVA (cytosolic, calcium-dependent)	approved; investigational	Celecoxib	CC1=CC=C(C=C1)C1=CC(=NN1C1=CC=C(C=C1)S(N)(=O)=O)C(F)(F)F
PLA2G6	DB01103	phospholipase A2, group VI (cytosolic, calcium-independent)	approved	Quinacrine	CCN(CC)CCCC(C)NC1=C2C=C(OC)C=CC2=NC2=C1C=CC(Cl)=C2
PLA2G7	DB07821	phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)	experimental	(1R)-1,2,2-TRIMETHYLPROPYL (R)-METHYLPHOSPHINATE	C[C@@H](OP(C)=O)C(C)(C)C
PLAUR	DB00122	plasminogen activator, urokinase receptor	approved; nutraceutical	Choline	C[N+](C)(C)CCO
PLCB1	DB00945	phospholipase C, beta 1 (phosphoinositide-specific)	approved	Acetylsalicylic acid	CC(=O)OC1=CC=CC=C1C(O)=O
PLCB1	DB00125	phospholipase C, beta 1 (phosphoinositide-specific)	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
PLCB1	DB00435	phospholipase C, beta 1 (phosphoinositide-specific)	approved	Nitric Oxide	[N]=O
PLCB1	DB00171	phospholipase C, beta 1 (phosphoinositide-specific)	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PLCB1	DB00988	phospholipase C, beta 1 (phosphoinositide-specific)	approved	Dopamine	NCCC1=CC(O)=C(O)C=C1
PLCB1	DB00917	phospholipase C, beta 1 (phosphoinositide-specific)	approved	Dinoprostone	CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O
PLCB1	DB01240	phospholipase C, beta 1 (phosphoinositide-specific)	approved	Epoprostenol	CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)C[C@@H]2OC(C[C@H]12)=CCCCC(O)=O
PLCB1	DB01115	phospholipase C, beta 1 (phosphoinositide-specific)	approved	Nifedipine	COC(=O)C1=C(C)NC(C)=C(C1C1=CC=CC=C1[N+]([O-])=O)C(=O)OC
PLCB2	DB01394	phospholipase C, beta 2	approved	Colchicine	COC1=C(OC)C(OC)=C2C(CC[C@H](NC(C)=O)C3=CC(=O)C(OC)=CC=C23)=C1
PLCB2	DB00988	phospholipase C, beta 2	approved	Dopamine	NCCC1=CC(O)=C(O)C=C1
PLCB2	DB00864	phospholipase C, beta 2	approved; investigational	Tacrolimus	CO[C@@H]1C[C@@H](CC[C@H]1O)\C=C(/C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H]([C@H](C[C@H]2C)OC)[C@H](C[C@@H](C)C\C(C)=C\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]1C)OC
PLCB2	DB00125	phospholipase C, beta 2	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
PLCB2	DB00435	phospholipase C, beta 2	approved	Nitric Oxide	[N]=O
PLCE1	DB00171	phospholipase C, epsilon 1	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PLCE1	DB00770	phospholipase C, epsilon 1	approved; investigational	Alprostadil	CCCCC[C@H](O)C=C[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(O)=O
PLCE1	DB00668	phospholipase C, epsilon 1	approved	Epinephrine	CNC[C@H](O)C1=CC(O)=C(O)C=C1
PLCG1	DB00171	phospholipase C, gamma 1	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PLCG1	DB00131	phospholipase C, gamma 1	approved; nutraceutical	Adenosine monophosphate	NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PLCG1	DB00125	phospholipase C, gamma 1	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
PLCG1	DB00155	phospholipase C, gamma 1	approved; nutraceutical	L-Citrulline	N[C@@H](CCCNC(N)=O)C(O)=O
PLCG1	DB00435	phospholipase C, gamma 1	approved	Nitric Oxide	[N]=O
PLCG1	DB00608	phospholipase C, gamma 1	approved	Chloroquine	CCN(CC)CCCC(C)NC1=C2C=CC(Cl)=CC2=NC=C1
PLCG1	DB00864	phospholipase C, gamma 1	approved; investigational	Tacrolimus	CO[C@@H]1C[C@@H](CC[C@H]1O)\C=C(/C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H]([C@H](C[C@H]2C)OC)[C@H](C[C@@H](C)C\C(C)=C\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]1C)OC
PLD1	DB00122	phospholipase D1, phosphatidylcholine-specific	approved; nutraceutical	Choline	C[N+](C)(C)CCO
PLD1	DB01394	phospholipase D1, phosphatidylcholine-specific	approved	Colchicine	COC1=C(OC)C(OC)=C2C(CC[C@H](NC(C)=O)C3=CC(=O)C(OC)=CC=C23)=C1
PLD1	DB00988	phospholipase D1, phosphatidylcholine-specific	approved	Dopamine	NCCC1=CC(O)=C(O)C=C1
PLD1	DB00864	phospholipase D1, phosphatidylcholine-specific	approved; investigational	Tacrolimus	CO[C@@H]1C[C@@H](CC[C@H]1O)\C=C(/C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H]([C@H](C[C@H]2C)OC)[C@H](C[C@@H](C)C\C(C)=C\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]1C)OC
PLD2	DB00122	phospholipase D2	approved; nutraceutical	Choline	C[N+](C)(C)CCO
PLD2	DB01394	phospholipase D2	approved	Colchicine	COC1=C(OC)C(OC)=C2C(CC[C@H](NC(C)=O)C3=CC(=O)C(OC)=CC=C23)=C1
PLD2	DB00988	phospholipase D2	approved	Dopamine	NCCC1=CC(O)=C(O)C=C1
PLD2	DB00864	phospholipase D2	approved; investigational	Tacrolimus	CO[C@@H]1C[C@@H](CC[C@H]1O)\C=C(/C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H]([C@H](C[C@H]2C)OC)[C@H](C[C@@H](C)C\C(C)=C\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]1C)OC
PLD2	DB00125	phospholipase D2	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
PLD2	DB00435	phospholipase D2	approved	Nitric Oxide	[N]=O
PMVK	DB01033	phosphomevalonate kinase	approved	Mercaptopurine	S=C1N=CNC2=C1NC=N2
PMVK	DB00563	phosphomevalonate kinase	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
PNLIP	DB01083	pancreatic lipase	approved; investigational	Orlistat	CCCCCCCCCCC[C@@H](C[C@@H]1OC(=O)[C@H]1CCCCCC)OC(=O)[C@H](CC(C)C)NC=O
PNLIP	DB04233	pancreatic lipase	experimental	(Hydroxyethyloxy)Tri(Ethyloxy)Octane	CCCCCCCCOCCOCCOCCOCCO
PNLIP	DB08222	pancreatic lipase	experimental	METHOXYUNDECYLPHOSPHINIC ACID	CCCCCCCCCCC[P@@](O)(=O)OC
PNLIPRP2	DB02613	pancreatic lipase-related protein 2	experimental	Decylamine-N,N-Dimethyl-N-Oxide	CCCCCCCCCC[N+](C)(C)[O-]
PNMT	DB01752	phenylethanolamine N-methyltransferase	experimental	S-Adenosyl-L-Homocysteine	N[C@@H](CCSC[C@@H]1O[C@H]([C@H](O)[C@H]1O)N1C=NC2=C1N=CN=C2N)C(O)=O
PNMT	DB03468	phenylethanolamine N-methyltransferase	experimental	1,2,3,4-Tetrahydro-Isoquinoline-7-Sulfonic Acid Amide	NS(=O)(=O)C1=CC2=C(CCNC2)C=C1
PNMT	DB03824	phenylethanolamine N-methyltransferase	experimental	7-Iodo-1,2,3,4-Tetrahydro-Isoquinoline	IC1=CC2=C(CCNC2)C=C1
PNMT	DB04273	phenylethanolamine N-methyltransferase	experimental	8,9-Dichloro-2,3,4,5-Tetrahydro-1h-Benzo[C]Azepine	ClC1=CC=C2CCCNCC2=C1Cl
PNMT	DB07597	phenylethanolamine N-methyltransferase	experimental	CIS-(1R,2S)-2-AMINO-1,2,3,4-TETRAHYDRONAPHTHALEN-1-OL	N[C@H]1CCC2=CC=CC=C2[C@H]1O
PNMT	DB07739	phenylethanolamine N-methyltransferase	experimental	(3R)-3-(FLUOROMETHYL)-7-(THIOMORPHOLIN-4-YLSULFONYL)-1,2,3,4-TETRAHYDROISOQUINOLINE	FC[C@H]1CC2=CC=C(C=C2CN1)S(=O)(=O)N1CCSCC1
PNMT	DB07747	phenylethanolamine N-methyltransferase	experimental	(3R)-N-(4-CHLOROPHENYL)-3-(HYDROXYMETHYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-7-SULFONAMIDE	OC[C@H]1CC2=CC=C(C=C2CN1)S(=O)(=O)NC1=CC=C(Cl)C=C1
PNMT	DB07798	phenylethanolamine N-methyltransferase	experimental	(3R)-3-(FLUOROMETHYL)-N-(3,3,3-TRIFLUOROPROPYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-7-SULFONAMIDE	FC[C@H]1CC2=CC=C(C=C2CN1)S(=O)(=O)NCCC(F)(F)F
PNMT	DB07906	phenylethanolamine N-methyltransferase	experimental	[(3R)-7-NITRO-1,2,3,4-TETRAHYDROISOQUINOLIN-3-YL]METHANOL	OC[C@H]1CC2=CC=C(C=C2CN1)[N+]([O-])=O
PNMT	DB08128	phenylethanolamine N-methyltransferase	experimental	(1S,4R,9S)-5-(trifluoromethyl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-9-amine	N[C@H]1[C@H]2CC[C@@H]1C1=C(C=CC=C21)C(F)(F)F
PNMT	DB08129	phenylethanolamine N-methyltransferase	experimental	(1R)-2-amino-1-[3-(trifluoromethyl)phenyl]ethanol	NC[C@H](O)C1=CC=CC(=C1)C(F)(F)F
PNMT	DB08550	phenylethanolamine N-methyltransferase	experimental	7,8-DICHLORO-1,2,3,4-TETRAHYDROISOQUINOLINE	ClC1=CC=C2CCNCC2=C1Cl
PNMT	DB08631	phenylethanolamine N-methyltransferase	experimental	N-(4-CHLOROPHENYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-7-SULFONAMIDE	ClC1=CC=C(NS(=O)(=O)C2=CC=C3CCNCC3=C2)C=C1
PNMT	DB08654	phenylethanolamine N-methyltransferase	experimental	TRANS-(1S,2S)-2-AMINO-1,2,3,4-TETRAHYDRONAPHTHALEN-1-OL	N[C@H]1CCC2=CC=CC=C2[C@@H]1O
PNMT	DB00988	phenylethanolamine N-methyltransferase	approved	Dopamine	NCCC1=CC(O)=C(O)C=C1
PNMT	DB00135	phenylethanolamine N-methyltransferase	approved; nutraceutical	L-Tyrosine	N[C@@H](CC1=CC=C(O)C=C1)C(O)=O
PNMT	DB00360	phenylethanolamine N-methyltransferase	approved; investigational	Tetrahydrobiopterin	CC(O)C(O)C1CNC2=C(N1)C(=O)N=C(N)N2
PNMT	DB00126	phenylethanolamine N-methyltransferase	approved; nutraceutical	Vitamin C	OC[C@H](O)[C@H]1OC(=O)C(O)=C1O
PNMT	DB01105	phenylethanolamine N-methyltransferase	illicit; approved; withdrawn; investigational	Sibutramine	CC(C)CC(N(C)C)C1(CCC1)C1=CC=C(Cl)C=C1
PNMT	DB00668	phenylethanolamine N-methyltransferase	approved	Epinephrine	CNC[C@H](O)C1=CC(O)=C(O)C=C1
PNMT	DB00368	phenylethanolamine N-methyltransferase	approved	Norepinephrine	NC[C@H](O)C1=CC(O)=C(O)C=C1
PNMT	DB01454	phenylethanolamine N-methyltransferase	illicit; experimental	3,4-Methylenedioxymethamphetamine	CNC(C)CC1=CC2=C(OCO2)C=C1
PNMT	DB01033	phenylethanolamine N-methyltransferase	approved	Mercaptopurine	S=C1N=CNC2=C1NC=N2
PNP	DB00242	purine nucleoside phosphorylase	approved; investigational	Cladribine	NC1=C2N=CN([C@H]3C[C@H](O)[C@@H](CO)O3)C2=NC(Cl)=N1
PNP	DB00900	purine nucleoside phosphorylase	approved	Didanosine	OC[C@@H]1CC[C@@H](O1)N1C=NC2=C1NC=NC2=O
PNP	DB01667	purine nucleoside phosphorylase	experimental	8-Azaguanine	Nc1nc(O)c2nnnc2n1
PNP	DB02222	purine nucleoside phosphorylase	experimental	2,6-Diamino-(S)-9-[2-(Phosphonomethoxy)Propyl]Purine	C[C@@H](CN1C=NC2=C1N=C(N)N=C2N)OCP([O-])([O-])=O
PNP	DB02230	purine nucleoside phosphorylase	experimental	Immucillin-G	NC1=Nc2c(cnc2C(=O)N1)[C@@H]1N[C@@H](CO)[C@H](O)[C@H]1O
PNP	DB02377	purine nucleoside phosphorylase	experimental	Guanine	NC1=Nc2ncnc2C(=O)N1
PNP	DB02391	purine nucleoside phosphorylase	experimental	2-Amino-7-[2-(2-Hydroxy-1-Hydroxymethyl-Ethylamino)-Ethyl]-1,7-Dihydro-Purin-6-One	NC1=NC2=C(N(CCNC(CO)CO)C=N2)C(=O)N1
PNP	DB02568	purine nucleoside phosphorylase	experimental	Peldesine	NC1=NC(=O)C2=C(N1)C(CC1=CN=CC=C1)=CN2
PNP	DB02796	purine nucleoside phosphorylase	experimental	9-Deazainosine	OC[C@@H]1O[C@H]([C@H](O)[C@H]1O)c1cnc2c1N=CNC2=O
PNP	DB02857	purine nucleoside phosphorylase	experimental	Guanosine	NC1=NC2=C(N=CN2[C@@H]2O[C@@H](CO)[C@H](O)[C@H]2O)C(=O)N1
PNP	DB03101	purine nucleoside phosphorylase	experimental	Ribose-1-Phosphate	OC[C@H]1O[C@H](OP(O)(O)=O)[C@H](O)[C@@H]1O
PNP	DB03551	purine nucleoside phosphorylase	experimental	4'-Deaza-1'-Aza-2'-Deoxy-1'-(9-Methylene)-Immucillin-H, (3r,4r)-N-[9-Deazahypoxanthin-9-Yl)Methyl]-4-Hydroxymethyl-Pyrrolidin-3-Ol	OC[C@H]1CN(CC2=CN[C@@H]3[C@H]2N=CNC3=O)C[C@@H]1O
PNP	DB03609	purine nucleoside phosphorylase	experimental	3-Deoxyguanosine	NC1=NC2=C(N=CN2[C@H]2O[C@H](CO)C[C@@H]2O)C(=O)N1
PNP	DB03881	purine nucleoside phosphorylase	experimental	MT-Immucillin-H	CSC[C@@H]1[NH2+][C@H]([C@H](O)[C@H]1O)c1cnc2c1N=CNC2=O
PNP	DB04076	purine nucleoside phosphorylase	experimental	Hypoxanthine	O=C1NC=Nc2ncnc12
PNP	DB04260	purine nucleoside phosphorylase	experimental	9-(5,5-Difluoro-5-Phosphonopentyl)Guanine	NC1=NC2=C(N=CN2CCCCC(F)(F)P(O)(O)=O)C(=O)N1
PNP	DB04753	purine nucleoside phosphorylase	experimental	9-DEAZAINOSINE-2',3'-O-ETHYLIDENEPHOSPHONATE	OC[C@H]1O[C@H]([C@@H]2O[C@H](CP(O)(O)=O)O[C@H]12)C1=CNC2=C1NC=NC2=O
PNP	DB04754	purine nucleoside phosphorylase	experimental	GUANOSINE-2',3'-O-ETHYLIDENEPHOSPHONATE	NC1=NC(=O)C2=C(N1)N(C=N2)[C@@H]1O[C@H](CO)[C@H]2O[C@@H](CP(O)(O)=O)O[C@@H]12
PNP	DB04757	purine nucleoside phosphorylase	experimental	GUANOSINE-2',3'-O-METHYLIDENEPHOSPHONATE	NC1=NC(=O)C2=C(N1)N(C=N2)[C@@H]1O[C@H](CO)[C@H]2O[C@@H](O[C@@H]12)P(O)(O)=O
PNP	DB03411	purine nucleoside phosphorylase	experimental	2-Hydroxymethyl-Pyrrolidine-3,4-Diol	OC[C@@H]1NC[C@H](O)[C@H]1O
PNP	DB04095	purine nucleoside phosphorylase	experimental	9-Deazahypoxanthine	O=C1NC=Nc2ccnc12
PNP	DB02985	purine nucleoside phosphorylase	experimental	8-Iodo-Guanine	NC1=Nc2nc(I)nc2C(=O)N1
PNPO	DB00114	pyridoxamine 5'-phosphate oxidase	nutraceutical	Pyridoxal Phosphate	CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O
PNPO	DB03247	pyridoxamine 5'-phosphate oxidase	experimental	Riboflavin Monophosphate	CC1=CC2=C(C=C1C)N(C[C@@H](O)[C@@H](O)[C@H](O)COP(O)(O)=O)C1=NC(=O)NC(=O)C1=N2
PNPO	DB03345	pyridoxamine 5'-phosphate oxidase	experimental	Beta-Mercaptoethanol	OCCS
POLA1	DB00242	polymerase (DNA directed), alpha 1, catalytic subunit	approved; investigational	Cladribine	NC1=C2N=CN([C@H]3C[C@H](O)[C@@H](CO)O3)C2=NC(Cl)=N1
POLA1	DB00631	polymerase (DNA directed), alpha 1, catalytic subunit	approved; investigational	Clofarabine	NC1=C2N=CN([C@@H]3O[C@H](CO)[C@@H](O)[C@@H]3F)C2=NC(Cl)=N1
POLA1	DB01073	polymerase (DNA directed), alpha 1, catalytic subunit	approved	Fludarabine	NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@@H]3O)C2=NC(F)=N1
POLA1	DB01280	polymerase (DNA directed), alpha 1, catalytic subunit	approved; investigational	Nelarabine	COC1=NC(N)=NC2=C1N=CN2[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O
POLA1	DB01050	polymerase (DNA directed), alpha 1, catalytic subunit	approved	Ibuprofen	CC(C)CC1=CC=C(C=C1)C(C)C(O)=O
POLA2	DB00851	polymerase (DNA directed), alpha 2, accessory subunit	approved	Dacarbazine	CN(C)\N=N\C1=C(N=CN1)C(N)=O
POLA2	DB00441	polymerase (DNA directed), alpha 2, accessory subunit	approved	Gemcitabine	NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](CO)[C@@H](O)C1(F)F
POLA2	DB01050	polymerase (DNA directed), alpha 2, accessory subunit	approved	Ibuprofen	CC(C)CC1=CC=C(C=C1)C(C)C(O)=O
POLD2	DB01050	polymerase (DNA directed), delta 2, accessory subunit	approved	Ibuprofen	CC(C)CC1=CC=C(C=C1)C(C)C(O)=O
POLD3	DB01050	polymerase (DNA-directed), delta 3, accessory subunit	approved	Ibuprofen	CC(C)CC1=CC=C(C=C1)C(C)C(O)=O
POLE	DB00242	polymerase (DNA directed), epsilon, catalytic subunit	approved; investigational	Cladribine	NC1=C2N=CN([C@H]3C[C@H](O)[C@@H](CO)O3)C2=NC(Cl)=N1
POLE	DB01033	polymerase (DNA directed), epsilon, catalytic subunit	approved	Mercaptopurine	S=C1N=CNC2=C1NC=N2
POLE	DB00563	polymerase (DNA directed), epsilon, catalytic subunit	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
POLE	DB00441	polymerase (DNA directed), epsilon, catalytic subunit	approved	Gemcitabine	NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](CO)[C@@H](O)C1(F)F
POLE2	DB00242	polymerase (DNA directed), epsilon 2, accessory subunit	approved; investigational	Cladribine	NC1=C2N=CN([C@H]3C[C@H](O)[C@@H](CO)O3)C2=NC(Cl)=N1
POLE2	DB01050	polymerase (DNA directed), epsilon 2, accessory subunit	approved	Ibuprofen	CC(C)CC1=CC=C(C=C1)C(C)C(O)=O
POLE3	DB00242	polymerase (DNA directed), epsilon 3, accessory subunit	approved; investigational	Cladribine	NC1=C2N=CN([C@H]3C[C@H](O)[C@@H](CO)O3)C2=NC(Cl)=N1
POLE4	DB00242	polymerase (DNA-directed), epsilon 4, accessory subunit	approved; investigational	Cladribine	NC1=C2N=CN([C@H]3C[C@H](O)[C@@H](CO)O3)C2=NC(Cl)=N1
POLE4	DB01050	polymerase (DNA-directed), epsilon 4, accessory subunit	approved	Ibuprofen	CC(C)CC1=CC=C(C=C1)C(C)C(O)=O
POLR2A	DB00269	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	approved	Chlorotrianisene	COC1=CC=C(C=C1)C(Cl)=C(C1=CC=C(OC)C=C1)C1=CC=C(OC)C=C1
POLR2A	DB00286	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	approved	Conjugated Estrogens	[Na+].C[C@]12CC[C@H]3[C@@H](CCC4=CC(OS([O-])(=O)=O)=CC=C34)[C@@H]1CCC2=O
POLR2A	DB00255	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	approved	Diethylstilbestrol	CCC(=C(CC)C1=CC=C(O)C=C1)C1=CC=C(O)C=C1
POLR2A	DB00783	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	approved; investigational	Estradiol	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CC[C@@H]2O
POLR2A	DB00655	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	approved	Estrone	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CCC2=O
POLR2A	DB00977	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	approved	Ethinyl Estradiol	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CC[C@@]2(O)C#C
POLR2A	DB00890	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	approved	Dienestrol	CC=C(C(=CC)C1=CC=C(O)C=C1)C1=CC=C(O)C=C1
POLR2A	DB00675	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	approved	Tamoxifen	CC\C(=C(/C1=CC=CC=C1)C1=CC=C(OCCN(C)C)C=C1)C1=CC=CC=C1
POLR2A	DB00394	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	approved	Beclomethasone	C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
POLR2A	DB00443	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	approved	Betamethasone	C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
POLR2A	DB01222	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	approved; investigational	Budesonide	CCC[C@H]1O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO
POLR2A	DB01410	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	approved; investigational	Ciclesonide	CC(C)C(=O)OCC(=O)[C@@]12OC(O[C@@H]1C[C@H]1[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@]21C)C1CCCCC1
POLR2A	DB01260	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	approved; investigational	Desonide	CC1(C)O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO
POLR2A	DB01234	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	approved; investigational	Dexamethasone	C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
POLR2A	DB00180	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	approved; investigational	Flunisolide	CC1(C)O[C@@H]2C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO
POLR2A	DB00588	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	approved; investigational	Fluticasone Propionate	CCC(=O)O[C@@]1([C@H](C)C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)C(=O)SCF
POLR2A	DB00741	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	approved	Hydrocortisone	C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
POLR2A	DB00959	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	approved	Methylprednisolone	C[C@H]1C[C@H]2[C@@H]3CC[C@](O)(C(=O)CO)[C@@]3(C)C[C@H](O)[C@@H]2[C@@]2(C)C=CC(=O)C=C12
POLR2A	DB00764	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	approved	Mometasone	C[C@@H]1C[C@H]2C3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CCl
POLR2A	DB01384	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	approved	Paramethasone	C[C@@H]1C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
POLR2A	DB00860	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	approved	Prednisolone	C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
POLR2A	DB00635	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	approved	Prednisone	C[C@]12CC(=O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
POLR2A	DB00896	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	approved	Rimexolone	CCC(=O)[C@@]1(C)[C@H](C)CC2C3CCC4=CC(=O)C=C[C@]4(C)C3[C@@H](O)C[C@]12C
POLR2A	DB00620	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	approved	Triamcinolone	C[C@]12C[C@H](O)[C@@]3(F)[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1C[C@@H](O)[C@]2(O)C(=O)CO
POMC	DB00836	proopiomelanocortin	approved	Loperamide	CN(C)C(=O)C(CCN1CCC(O)(CC1)C1=CC=C(Cl)C=C1)(C1=CC=CC=C1)C1=CC=CC=C1
POMC	DB01497	proopiomelanocortin	illicit; experimental	Etorphine	CCCC(C)(O)C1C[C@@]23C=CC1(OC)C1OC4=C(O)C=CC5=C4[C@]21CCN(C)[C@@H]3C5
POMC	DB01565	proopiomelanocortin	illicit; experimental	Dihydromorphine	CN1CC[C@]23[C@H]4OC5=C(O)C=CC(C[C@@H]1[C@@H]2CC[C@@H]4O)=C35
POMC	DB00269	proopiomelanocortin	approved	Chlorotrianisene	COC1=CC=C(C=C1)C(Cl)=C(C1=CC=C(OC)C=C1)C1=CC=C(OC)C=C1
POMC	DB00286	proopiomelanocortin	approved	Conjugated Estrogens	[Na+].C[C@]12CC[C@H]3[C@@H](CCC4=CC(OS([O-])(=O)=O)=CC=C34)[C@@H]1CCC2=O
POMC	DB00890	proopiomelanocortin	approved	Dienestrol	CC=C(C(=CC)C1=CC=C(O)C=C1)C1=CC=C(O)C=C1
POMC	DB00255	proopiomelanocortin	approved	Diethylstilbestrol	CCC(=C(CC)C1=CC=C(O)C=C1)C1=CC=C(O)C=C1
POMC	DB00783	proopiomelanocortin	approved; investigational	Estradiol	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CC[C@@H]2O
POMC	DB00655	proopiomelanocortin	approved	Estrone	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CCC2=O
POMC	DB00977	proopiomelanocortin	approved	Ethinyl Estradiol	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CC[C@@]2(O)C#C
PPARA	DB00636	peroxisome proliferator-activated receptor alpha	approved	Clofibrate	CCOC(=O)C(C)(C)OC1=CC=C(Cl)C=C1
PPARA	DB01039	peroxisome proliferator-activated receptor alpha	approved	Fenofibrate	CC(C)OC(=O)C(C)(C)OC1=CC=C(C=C1)C(=O)C1=CC=C(Cl)C=C1
PPARA	DB01241	peroxisome proliferator-activated receptor alpha	approved	Gemfibrozil	CC1=CC(OCCCC(C)(C)C(O)=O)=C(C)C=C1
PPARA	DB01393	peroxisome proliferator-activated receptor alpha	approved	Bezafibrate	CC(C)(OC1=CC=C(CCNC(=O)C2=CC=C(Cl)C=C2)C=C1)C(O)=O
PPARA	DB01890	peroxisome proliferator-activated receptor alpha	experimental	Deoxy-Bigchap	C[C@H](CCC(=O)N(CCCNC(=O)[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)CCCNC(=O)[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)[C@@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@@H](O)CC[C@]4(C)[C@H]3C[C@@H](O)[C@]12C
PPARA	DB07215	peroxisome proliferator-activated receptor alpha	experimental	2-METHYL-2-(4-{[({4-METHYL-2-[4-(TRIFLUOROMETHYL)PHENYL]-1,3-THIAZOL-5-YL}CARBONYL)AMINO]METHYL}PHENOXY)PROPANOIC ACID	CC1=C(SC(=N1)C1=CC=C(C=C1)C(F)(F)F)C(=O)NCC1=CC=C(OC(C)(C)C(O)=O)C=C1
PPARA	DB07724	peroxisome proliferator-activated receptor alpha	experimental	3-{5-methoxy-1-[(4-methoxyphenyl)sulfonyl]-1H-indol-3-yl}propanoic acid	COC1=CC=C(C=C1)S(=O)(=O)N1C=C(CCC(O)=O)C2=CC(OC)=CC=C12
PPARA	DB08483	peroxisome proliferator-activated receptor alpha	experimental	(2S)-2-methoxy-3-{4-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]-1-benzothiophen-7-yl}propanoic acid	CO[C@@H](CC1=CC=C(OCCC2=C(C)OC(=N2)C2=CC=CC=C2)C2=C1SC=C2)C(O)=O
PPARA	DB00724	peroxisome proliferator-activated receptor alpha	approved; investigational	Imiquimod	CC(C)CN1C=NC2=C1C1=CC=CC=C1N=C2N
PPARG	DB00159	peroxisome proliferator-activated receptor gamma	approved; nutraceutical	Icosapent	CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O
PPARG	DB00197	peroxisome proliferator-activated receptor gamma	withdrawn	Troglitazone	CC1=C(C)C2=C(CCC(C)(COC3=CC=C(CC4SC(=O)NC4=O)C=C3)O2)C(C)=C1O
PPARG	DB00244	peroxisome proliferator-activated receptor gamma	approved	Mesalazine	NC1=CC(C(O)=O)=C(O)C=C1
PPARG	DB00328	peroxisome proliferator-activated receptor gamma	approved; investigational	Indomethacin	COC1=CC2=C(C=C1)N(C(=O)C1=CC=C(Cl)C=C1)C(C)=C2CC(O)=O
PPARG	DB00412	peroxisome proliferator-activated receptor gamma	approved; investigational	Rosiglitazone	CN(CCOC1=CC=C(CC2SC(=O)NC2=O)C=C1)C1=CC=CC=N1
PPARG	DB00731	peroxisome proliferator-activated receptor gamma	approved; investigational	Nateglinide	CC(C)C1CC[C@@H](CC1)C(=O)N[C@H](CC1=CC=CC=C1)C(O)=O
PPARG	DB00795	peroxisome proliferator-activated receptor gamma	approved	Sulfasalazine	OC(=O)C1=CC(=CC=C1O)\N=N\C1=CC=C(C=C1)S(=O)(=O)NC1=NC=CC=C1
PPARG	DB00912	peroxisome proliferator-activated receptor gamma	approved; investigational	Repaglinide	CCOC1=C(C=CC(CC(=O)N[C@@H](CC(C)C)C2=CC=CC=C2N2CCCCC2)=C1)C(O)=O
PPARG	DB00966	peroxisome proliferator-activated receptor gamma	approved; investigational	Telmisartan	CCCC1=NC2=C(C=C(C=C2C)C2=NC3=CC=CC=C3N2C)N1CC1=CC=C(C=C1)C1=CC=CC=C1C(O)=O
PPARG	DB01014	peroxisome proliferator-activated receptor gamma	approved; investigational	Balsalazide	OC(=O)CCNC(=O)C1=CC=C(N\N=C2\C=CC(=O)C(=C2)C(O)=O)C=C1
PPARG	DB01067	peroxisome proliferator-activated receptor gamma	approved	Glipizide	CC1=CN=C(C=N1)C(=O)NCCC1=CC=C(C=C1)S(=O)(=O)NC(=O)NC1CCCCC1
PPARG	DB01132	peroxisome proliferator-activated receptor gamma	approved; investigational	Pioglitazone	CCC1=CN=C(CCOC2=CC=C(CC3SC(=O)NC3=O)C=C2)C=C1
PPARG	DB01252	peroxisome proliferator-activated receptor gamma	approved; investigational	Mitiglinide	OC(=O)C(CC(=O)N1CC2CCCCC2C1)CC1=CC=CC=C1
PPARG	DB01393	peroxisome proliferator-activated receptor gamma	approved	Bezafibrate	CC(C)(OC1=CC=C(CCNC(=O)C2=CC=C(Cl)C=C2)C=C1)C(O)=O
PPARG	DB04270	peroxisome proliferator-activated receptor gamma	experimental	(S)-3-(4-(2-Carbazol-9-Yl-Ethoxy)-Phenyl)-2-Ethoxy-Propionic Acid	CCO[C@@H](CC1=CC=C(OCCN2C3=C(C=CC=C3)C3=C2C=CC=C3)C=C1)C(O)=O
PPARG	DB04689	peroxisome proliferator-activated receptor gamma	experimental	2-{5-[3-(6-BENZOYL-1-PROPYLNAPHTHALEN-2-YLOXY)PROPOXY]INDOL-1-YL}ETHANOIC ACID	CCCC1=C(OCCCOC2=CC3=C(C=C2)N(CC(O)=O)C=C3)C=CC2=C1C=CC(=C2)C(=O)C1=CC=CC=C1
PPARG	DB06908	peroxisome proliferator-activated receptor gamma	experimental	(2S)-3-(1-{[2-(2-CHLOROPHENYL)-5-METHYL-1,3-OXAZOL-4-YL]METHYL}-1H-INDOL-5-YL)-2-ETHOXYPROPANOIC ACID	CCO[C@@H](CC1=CC2=C(C=C1)N(CC1=C(C)OC(=N1)C1=C(Cl)C=CC=C1)C=C2)C(O)=O
PPARG	DB06926	peroxisome proliferator-activated receptor gamma	experimental	(9Z,11E,13S)-13-hydroxyoctadeca-9,11-dienoic acid	CCCCC[C@H](O)\C=C\C=C/CCCCCCCC(O)=O
PPARG	DB07053	peroxisome proliferator-activated receptor gamma	experimental	2-{5-[3-(7-PROPYL-3-TRIFLUOROMETHYLBENZO[D]ISOXAZOL-6-YLOXY)PROPOXY]INDOL-1-YL}ETHANOIC ACID	CCCC1=C2ON=C(C2=CC=C1OCCCOC1=CC2=C(C=C1)N(CC(O)=O)C=C2)C(F)(F)F
PPARG	DB07111	peroxisome proliferator-activated receptor gamma	experimental	(4S,5E,7Z,10Z,13Z,16Z,19Z)-4-hydroxydocosa-5,7,10,13,16,19-hexaenoic acid	CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/C=C/[C@@H](O)CCC(O)=O
PPARG	DB07172	peroxisome proliferator-activated receptor gamma	experimental	(5R,6E,8Z,11Z,14Z,17Z)-5-hydroxyicosa-6,8,11,14,17-pentaenoic acid	CC\C=C/C\C=C/C\C=C/C\C=C/C=C/[C@H](O)CCCC(O)=O
PPARG	DB07208	peroxisome proliferator-activated receptor gamma	experimental	(8E,10S,12Z)-10-hydroxy-6-oxooctadeca-8,12-dienoic acid	CCCCC\C=C/C[C@H](O)\C=C\CC(=O)CCCCC(O)=O
PPARG	DB07209	peroxisome proliferator-activated receptor gamma	experimental	(8R,9Z,12Z)-8-hydroxy-6-oxooctadeca-9,12-dienoic acid	CCCCC\C=C/C\C=C/[C@H](O)CC(=O)CCCCC(O)=O
PPARG	DB07302	peroxisome proliferator-activated receptor gamma	experimental	(9S,10E,12Z)-9-hydroxyoctadeca-10,12-dienoic acid	CCCCC\C=C/C=C/[C@@H](O)CCCCCCCC(O)=O
PPARG	DB07509	peroxisome proliferator-activated receptor gamma	experimental	difluoro(5-{2-[(5-octyl-1H-pyrrol-2-yl-kappaN)methylidene]-2H-pyrrol-5-yl-kappaN}pentanoato)boron	CCCCCCCCC1=CC=C2C=C3C=CC(CCCCC(O)=O)=[N+]3[B-](F)(F)N12
PPARG	DB07675	peroxisome proliferator-activated receptor gamma	experimental	(2S)-2-ETHOXY-3-{4-[2-(10H-PHENOXAZIN-10-YL)ETHOXY]PHENYL}PROPANOIC ACID	CCO[C@@H](CC1=CC=C(OCCN2C3=C(OC4=C2C=CC=C4)C=CC=C3)C=C1)C(O)=O
PPARG	DB07723	peroxisome proliferator-activated receptor gamma	experimental	3-(5-methoxy-1H-indol-3-yl)propanoic acid	COC1=CC=C2NC=C(CCC(O)=O)C2=C1
PPARG	DB07724	peroxisome proliferator-activated receptor gamma	experimental	3-{5-methoxy-1-[(4-methoxyphenyl)sulfonyl]-1H-indol-3-yl}propanoic acid	COC1=CC=C(C=C1)S(=O)(=O)N1C=C(CCC(O)=O)C2=CC(OC)=CC=C12
PPARG	DB07842	peroxisome proliferator-activated receptor gamma	experimental	(2S)-2-(4-ethylphenoxy)-3-phenylpropanoic acid	CCC1=CC=C(O[C@@H](CC2=CC=CC=C2)C(O)=O)C=C1
PPARG	DB07863	peroxisome proliferator-activated receptor gamma	experimental	2-chloro-5-nitro-N-phenylbenzamide	[O-][N+](=O)C1=CC=C(Cl)C(=C1)C(=O)NC1=CC=CC=C1
PPARG	DB08121	peroxisome proliferator-activated receptor gamma	experimental	(2S)-2-(biphenyl-4-yloxy)-3-phenylpropanoic acid	OC(=O)[C@H](CC1=CC=CC=C1)OC1=CC=C(C=C1)C1=CC=CC=C1
PPARG	DB08302	peroxisome proliferator-activated receptor gamma	experimental	3-[5-(2-nitropent-1-en-1-yl)furan-2-yl]benzoic acid	CCC\C(=C\C1=CC=C(O1)C1=CC(=CC=C1)C(O)=O)[N+]([O-])=O
PPARG	DB08402	peroxisome proliferator-activated receptor gamma	experimental	2-[(2,4-DICHLOROBENZOYL)AMINO]-5-(PYRIMIDIN-2-YLOXY)BENZOIC ACID	OC(=O)C1=C(NC(=O)C2=C(Cl)C=C(Cl)C=C2)C=CC(OC2=NC=CC=N2)=C1
PPARG	DB08435	peroxisome proliferator-activated receptor gamma	experimental	(5E,14E)-11-oxoprosta-5,9,12,14-tetraen-1-oic acid	CCCCC\C=C\C=C1\[C@@H](C\C=C\CCCC(O)=O)C=CC1=O
PPARG	DB08483	peroxisome proliferator-activated receptor gamma	experimental	(2S)-2-methoxy-3-{4-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]-1-benzothiophen-7-yl}propanoic acid	CO[C@@H](CC1=CC=C(OCCC2=C(C)OC(=N2)C2=CC=CC=C2)C2=C1SC=C2)C(O)=O
PPARG	DB08560	peroxisome proliferator-activated receptor gamma	experimental	3-FLUORO-N-[1-(4-FLUOROPHENYL)-3-(2-THIENYL)-1H-PYRAZOL-5-YL]BENZENESULFONAMIDE	FC1=CC=C(C=C1)N1N=C(C=C1NS(=O)(=O)C1=CC=CC(F)=C1)C1=CC=CS1
PPARG	DB08760	peroxisome proliferator-activated receptor gamma	experimental	(2S)-2-(4-chlorophenoxy)-3-phenylpropanoic acid	OC(=O)[C@H](CC1=CC=CC=C1)OC1=CC=C(Cl)C=C1
PPARG	DB00755	peroxisome proliferator-activated receptor gamma	approved; nutraceutical; investigational	Tretinoin	CC(C=CC1=C(C)CCCC1(C)C)=CC=CC(C)=CC(O)=O
PPARG	DB00945	peroxisome proliferator-activated receptor gamma	approved	Acetylsalicylic acid	CC(=O)OC1=CC=CC=C1C(O)=O
PPARG	DB00741	peroxisome proliferator-activated receptor gamma	approved	Hydrocortisone	C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
PPARG	DB00482	peroxisome proliferator-activated receptor gamma	approved; investigational	Celecoxib	CC1=CC=C(C=C1)C1=CC(=NN1C1=CC=C(C=C1)S(N)(=O)=O)C(F)(F)F
PPARGC1A	DB01132	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	approved; investigational	Pioglitazone	CCC1=CN=C(CCOC2=CC=C(CC3SC(=O)NC3=O)C=C2)C=C1
PPAT	DB00130	phosphoribosyl pyrophosphate amidotransferase	approved; nutraceutical; investigational	L-Glutamine	N[C@@H](CCC(N)=O)C(O)=O
PPAT	DB01972	phosphoribosyl pyrophosphate amidotransferase	experimental	Guanosine-5'-Monophosphate	NC1=NC2=C(N=CN2[C@@H]2O[C@@H](COP(O)(O)=O)[C@H](O)[C@H]2O)C(=O)N1
PPAT	DB03431	phosphoribosyl pyrophosphate amidotransferase	experimental	Adenosine-5'-Diphosphate	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](CO[P@](O)(=O)OP(O)(O)=O)[C@H](O)[C@H]1O
PPAT	DB03942	phosphoribosyl pyrophosphate amidotransferase	experimental	Carboxylic PRPP	O[C@@H]1[C@@H](O)[C@@H](C[C@H]1COP(O)(O)=O)O[P@](O)(=O)OP(O)(O)=O
PPAT	DB04296	phosphoribosyl pyrophosphate amidotransferase	experimental	5-Oxo-L-Norleucine	CC(=O)CC[C@@H](N)C(O)=O
PPAT	DB00145	phosphoribosyl pyrophosphate amidotransferase	approved; nutraceutical	Glycine	NCC(O)=O
PPAT	DB00563	phosphoribosyl pyrophosphate amidotransferase	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
PPCDC	DB03247	phosphopantothenoylcysteine decarboxylase	experimental	Riboflavin Monophosphate	CC1=CC2=C(C=C1C)N(C[C@@H](O)[C@@H](O)[C@H](O)COP(O)(O)=O)C1=NC(=O)NC(=O)C1=N2
PPCDC	DB03738	phosphopantothenoylcysteine decarboxylase	experimental	Pantothenoylaminoethenethiol	OCC(C)(C)[C@@H](O)C(=O)NCCC(=O)N\C=C\S
PPCDC	DB00151	phosphopantothenoylcysteine decarboxylase	approved; nutraceutical	L-Cysteine	N[C@@H](CS)C(O)=O
PPCS	DB00151	phosphopantothenoylcysteine synthetase	approved; nutraceutical	L-Cysteine	N[C@@H](CS)C(O)=O
PPOX	DB00145	protoporphyrinogen oxidase	approved; nutraceutical	Glycine	NCC(O)=O
PPP1CA	DB02506	protein phosphatase 1, catalytic subunit, alpha isozyme	experimental	2,6,8-Trimethyl-3-Amino-9-Benzyl-9-Methoxynonanoic Acid	CO[C@@H](CC1=CC=CC=C1)[C@@H](C)C[C@H](C)CC[C@H](N)[C@H](C)C(O)=O
PPP1CA	DB00171	protein phosphatase 1, catalytic subunit, alpha isozyme	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PPP1CA	DB00988	protein phosphatase 1, catalytic subunit, alpha isozyme	approved	Dopamine	NCCC1=CC(O)=C(O)C=C1
PPP1CB	DB01033	protein phosphatase 1, catalytic subunit, beta isozyme	approved	Mercaptopurine	S=C1N=CNC2=C1NC=N2
PPP1CB	DB00563	protein phosphatase 1, catalytic subunit, beta isozyme	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
PPP2CA	DB00163	protein phosphatase 2, catalytic subunit, alpha isozyme	approved; nutraceutical	Vitamin E	CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCC2=C(O1)C(C)=C(C)C(O)=C2C
PPP2CA	DB02506	protein phosphatase 2, catalytic subunit, alpha isozyme	experimental	2,6,8-Trimethyl-3-Amino-9-Benzyl-9-Methoxynonanoic Acid	CO[C@@H](CC1=CC=CC=C1)[C@@H](C)C[C@H](C)CC[C@H](N)[C@H](C)C(O)=O
PPP2CA	DB06905	protein phosphatase 2, catalytic subunit, alpha isozyme	experimental	(2S,3S,4E,6E,8S,9S)-3-amino-9-methoxy-2,6,8-trimethyl-10-phenyldeca-4,6-dienoic acid	CO[C@@H](CC1=CC=CC=C1)[C@@H](C)\C=C(/C)\C=C\[C@H](N)[C@H](C)C(O)=O
PPP2CA	DB00877	protein phosphatase 2, catalytic subunit, alpha isozyme	approved; investigational	Sirolimus	CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1O
PPP2CB	DB00163	protein phosphatase 2, catalytic subunit, beta isozyme	approved; nutraceutical	Vitamin E	CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCC2=C(O1)C(C)=C(C)C(O)=C2C
PPP2R1A	DB02506	protein phosphatase 2, regulatory subunit A, alpha	experimental	2,6,8-Trimethyl-3-Amino-9-Benzyl-9-Methoxynonanoic Acid	CO[C@@H](CC1=CC=CC=C1)[C@@H](C)C[C@H](C)CC[C@H](N)[C@H](C)C(O)=O
PPP2R1A	DB06905	protein phosphatase 2, regulatory subunit A, alpha	experimental	(2S,3S,4E,6E,8S,9S)-3-amino-9-methoxy-2,6,8-trimethyl-10-phenyldeca-4,6-dienoic acid	CO[C@@H](CC1=CC=CC=C1)[C@@H](C)\C=C(/C)\C=C\[C@H](N)[C@H](C)C(O)=O
PPP2R2A	DB02506	protein phosphatase 2, regulatory subunit B, alpha	experimental	2,6,8-Trimethyl-3-Amino-9-Benzyl-9-Methoxynonanoic Acid	CO[C@@H](CC1=CC=CC=C1)[C@@H](C)C[C@H](C)CC[C@H](N)[C@H](C)C(O)=O
PPP2R5D	DB00675	protein phosphatase 2, regulatory subunit B', delta	approved	Tamoxifen	CC\C(=C(/C1=CC=CC=C1)C1=CC=C(OCCN(C)C)C=C1)C1=CC=CC=C1
PPP2R5D	DB01394	protein phosphatase 2, regulatory subunit B', delta	approved	Colchicine	COC1=C(OC)C(OC)=C2C(CC[C@H](NC(C)=O)C3=CC(=O)C(OC)=CC=C23)=C1
PPP2R5D	DB00864	protein phosphatase 2, regulatory subunit B', delta	approved; investigational	Tacrolimus	CO[C@@H]1C[C@@H](CC[C@H]1O)\C=C(/C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H]([C@H](C[C@H]2C)OC)[C@H](C[C@@H](C)C\C(C)=C\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]1C)OC
PPP2R5D	DB00877	protein phosphatase 2, regulatory subunit B', delta	approved; investigational	Sirolimus	CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1O
PPP2R5D	DB00131	protein phosphatase 2, regulatory subunit B', delta	approved; nutraceutical	Adenosine monophosphate	NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PPP2R5D	DB00171	protein phosphatase 2, regulatory subunit B', delta	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PPP2R5D	DB00988	protein phosphatase 2, regulatory subunit B', delta	approved	Dopamine	NCCC1=CC(O)=C(O)C=C1
PRDX6	DB03661	peroxiredoxin 6	experimental	Cysteinesulfonic Acid	N[C@@H](CS(O)(=O)=O)C(O)=O
PRKAA1	DB00131	protein kinase, AMP-activated, alpha 1 catalytic subunit	approved; nutraceutical	Adenosine monophosphate	NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PRKAA1	DB00171	protein kinase, AMP-activated, alpha 1 catalytic subunit	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PRKAA1	DB00914	protein kinase, AMP-activated, alpha 1 catalytic subunit	approved; withdrawn	Phenformin	NC(=N)NC(=N)NCCC1=CC=CC=C1
PRKAA1	DB01174	protein kinase, AMP-activated, alpha 1 catalytic subunit	approved	Phenobarbital	CCC1(C(=O)NC(=O)NC1=O)C1=CC=CC=C1
PRKAA1	DB00412	protein kinase, AMP-activated, alpha 1 catalytic subunit	approved; investigational	Rosiglitazone	CN(CCOC1=CC=C(CC2SC(=O)NC2=O)C=C1)C1=CC=CC=N1
PRKAA1	DB01132	protein kinase, AMP-activated, alpha 1 catalytic subunit	approved; investigational	Pioglitazone	CCC1=CN=C(CCOC2=CC=C(CC3SC(=O)NC3=O)C=C2)C=C1
PRKAA1	DB00331	protein kinase, AMP-activated, alpha 1 catalytic subunit	approved	Metformin	CN(C)C(=N)NC(N)=N
PRKAA2	DB00131	protein kinase, AMP-activated, alpha 2 catalytic subunit	approved; nutraceutical	Adenosine monophosphate	NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PRKAA2	DB00171	protein kinase, AMP-activated, alpha 2 catalytic subunit	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PRKAA2	DB00412	protein kinase, AMP-activated, alpha 2 catalytic subunit	approved; investigational	Rosiglitazone	CN(CCOC1=CC=C(CC2SC(=O)NC2=O)C=C1)C1=CC=CC=N1
PRKAA2	DB01132	protein kinase, AMP-activated, alpha 2 catalytic subunit	approved; investigational	Pioglitazone	CCC1=CN=C(CCOC2=CC=C(CC3SC(=O)NC3=O)C=C2)C=C1
PRKAA2	DB00331	protein kinase, AMP-activated, alpha 2 catalytic subunit	approved	Metformin	CN(C)C(=N)NC(N)=N
PRKAB1	DB00131	protein kinase, AMP-activated, beta 1 non-catalytic subunit	approved; nutraceutical	Adenosine monophosphate	NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PRKAB1	DB00331	protein kinase, AMP-activated, beta 1 non-catalytic subunit	approved	Metformin	CN(C)C(=N)NC(N)=N
PRKAB1	DB00877	protein kinase, AMP-activated, beta 1 non-catalytic subunit	approved; investigational	Sirolimus	CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1O
PRKAB1	DB00171	protein kinase, AMP-activated, beta 1 non-catalytic subunit	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PRKAB1	DB00412	protein kinase, AMP-activated, beta 1 non-catalytic subunit	approved; investigational	Rosiglitazone	CN(CCOC1=CC=C(CC2SC(=O)NC2=O)C=C1)C1=CC=CC=N1
PRKAB1	DB01132	protein kinase, AMP-activated, beta 1 non-catalytic subunit	approved; investigational	Pioglitazone	CCC1=CN=C(CCOC2=CC=C(CC3SC(=O)NC3=O)C=C2)C=C1
PRKAB2	DB00131	protein kinase, AMP-activated, beta 2 non-catalytic subunit	approved; nutraceutical	Adenosine monophosphate	NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PRKAB2	DB00171	protein kinase, AMP-activated, beta 2 non-catalytic subunit	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PRKAB2	DB00412	protein kinase, AMP-activated, beta 2 non-catalytic subunit	approved; investigational	Rosiglitazone	CN(CCOC1=CC=C(CC2SC(=O)NC2=O)C=C1)C1=CC=CC=N1
PRKAB2	DB01132	protein kinase, AMP-activated, beta 2 non-catalytic subunit	approved; investigational	Pioglitazone	CCC1=CN=C(CCOC2=CC=C(CC3SC(=O)NC3=O)C=C2)C=C1
PRKAB2	DB00331	protein kinase, AMP-activated, beta 2 non-catalytic subunit	approved	Metformin	CN(C)C(=N)NC(N)=N
PRKACA	DB01919	protein kinase, cAMP-dependent, catalytic, alpha	experimental	Pentanal	CCCCC=O
PRKACA	DB01940	protein kinase, cAMP-dependent, catalytic, alpha	experimental	Balanol Analog 2	OC1=CC=C(C=C1)C(=O)N[C@H]1CNCCC[C@H]1OC(=O)C1=CC=C(C=C1)C(=O)C1=CC=CC=C1O
PRKACA	DB02155	protein kinase, cAMP-dependent, catalytic, alpha	experimental	Balanol Analog 8	CC[C@@H](C)C1=CC(=CC=C1O)C(=O)N[C@H]1CNCCC[C@H]1OC(=O)C1=CC=C(C=C1)C(=O)C1=CC(OC)=CC=C1O
PRKACA	DB02440	protein kinase, cAMP-dependent, catalytic, alpha	experimental	N-Octane	CCCCCCCC
PRKACA	DB02482	protein kinase, cAMP-dependent, catalytic, alpha	experimental	Phosphonothreonine	C[C@H](OP(O)(O)=O)[C@@H](N)C(O)=O
PRKACA	DB02611	protein kinase, cAMP-dependent, catalytic, alpha	experimental	Balanol Analog 1	OC1=CC=C(C=C1)C(=O)N[C@@H]1CNCCC[C@H]1OC(=O)C1=CC=C(O)C=C1
PRKACA	DB03374	protein kinase, cAMP-dependent, catalytic, alpha	experimental	3,5-Diiodotyrosine	N[C@@H](CC1=CC(I)=C(O)C(I)=C1)C(O)=O
PRKACA	DB04098	protein kinase, cAMP-dependent, catalytic, alpha	experimental	Balanol	OC(=O)C1=CC=CC(O)=C1C(=O)C1=C(O)C=C(C=C1O)C(=O)O[C@@H]1CCCNC[C@@H]1NC(=O)C1=CC=C(O)C=C1
PRKACA	DB04522	protein kinase, cAMP-dependent, catalytic, alpha	experimental	Phosphonoserine	N[C@@H](COP(O)(O)=O)C(O)=O
PRKACA	DB04530	protein kinase, cAMP-dependent, catalytic, alpha	experimental	S,S-(2-Hydroxyethyl)Thiocysteine	N[C@@H](CSSCCO)C(O)=O
PRKACA	DB04707	protein kinase, cAMP-dependent, catalytic, alpha	experimental	HYDROXYFASUDIL	OC1=C2C=CC=C(C2=CC=N1)S(=O)(=O)N1CCCNCC1
PRKACA	DB06959	protein kinase, cAMP-dependent, catalytic, alpha	experimental	(1S)-2-(1H-INDOL-3-YL)-1-{[(5-ISOQUINOLIN-6-YLPYRIDIN-3-YL)OXY]METHYL}ETHYLAMINE	N[C@H](COC1=CN=CC(=C1)C1=CC2=C(C=C1)C=NC=C2)C[C@H]1C=NC2=C1C=CC=C2
PRKACA	DB06977	protein kinase, cAMP-dependent, catalytic, alpha	experimental	(2S)-1-{[5-(1H-INDAZOL-5-YL)PYRIDIN-3-YL]OXY}-3-[(7AS)-7AH-INDOL-3-YL]PROPAN-2-AMINE	N[C@H](COC1=CC(=CN=C1)C1=CC2=C(NN=C2)C=C1)CC1=C2C=CC=C[C@H]2N=C1
PRKACA	DB07107	protein kinase, cAMP-dependent, catalytic, alpha	experimental	(1S)-2-(1H-INDOL-3-YL)-1-[({5-[(E)-2-PYRIDIN-4-YLVINYL]PYRIDIN-3-YL}OXY)METHYL]ETHYLAMINE	N[C@H](COC1=CN=CC(\C=C\C2=CC=NC=C2)=C1)CC1=CNC2=C1C=CC=C2
PRKACA	DB07124	protein kinase, cAMP-dependent, catalytic, alpha	experimental	(2S)-1-(6H-INDOL-3-YL)-3-{[5-(7H-PYRAZOLO[3,4-C]PYRIDIN-5-YL)PYRIDIN-3-YL]OXY}PROPAN-2-AMINE	N[C@H](COC1=CN=CC(=C1)C1=NCC2=NN=CC2=C1)CC1=C2C=CCC=C2N=C1
PRKACA	DB07204	protein kinase, cAMP-dependent, catalytic, alpha	experimental	(1S)-1-(1H-INDOL-3-YLMETHYL)-2-(2-PYRIDIN-4-YL-[1,7]NAPHTYRIDIN-5-YLOXY)-EHYLAMINE	N[C@H](COC1=C2C=CC(=NC2=CN=C1)C1=CC=NC=C1)CC1=CNC2=C1C=CC=C2
PRKACA	DB07235	protein kinase, cAMP-dependent, catalytic, alpha	experimental	N-[(1S)-2-AMINO-1-(2,4-DICHLOROBENZYL)ETHYL]-5-[2-(METHYLAMINO)PYRIMIDIN-4-YL]THIOPHENE-2-CARBOXAMIDE	CNC1=NC(=CC=N1)C1=CC=C(S1)C(=O)N[C@H](CN)CC1=C(Cl)C=C(Cl)C=C1
PRKACA	DB07458	protein kinase, cAMP-dependent, catalytic, alpha	experimental	3-(1H-INDOL-3-YL)-4-{1-[2-(1-METHYLPYRROLIDIN-2-YL)ETHYL]-1H-INDOL-3-YL}-1H-PYRROLE-2,5-DIONE	CN1CCC[C@H]1CCN1C=C(C2=C1C=CC=C2)C1=C(C(=O)NC1=O)C1=CNC2=C1C=CC=C2
PRKACA	DB07583	protein kinase, cAMP-dependent, catalytic, alpha	experimental	(4R,2S)-5'-(4-(4-CHLOROBENZYLOXY)PYRROLIDIN-2-YLMETHANESULFONYL)ISOQUINOLINE	ClC1=CC=C(CO[C@H]2CN[C@H](CNS(=O)(=O)C3=CC=CC4=CN=CC=C34)C2)C=C1
PRKACA	DB07854	protein kinase, cAMP-dependent, catalytic, alpha	experimental	N-METHYL-1-[4-(9H-PURIN-6-YL)PHENYL]METHANAMINE	CNCC1=CC=C(C=C1)C1=NC=NC2=C1N=CN2
PRKACA	DB07855	protein kinase, cAMP-dependent, catalytic, alpha	experimental	(S)-1-PHENYL-1-[4-(9H-PURIN-6-YL)PHENYL]METHANAMINE	N[C@@H](C1=CC=CC=C1)C1=CC=C(C=C1)C1=C2N=CNC2=NC=N1
PRKACA	DB07856	protein kinase, cAMP-dependent, catalytic, alpha	experimental	6-{4-[4-(4-CHLOROPHENYL)PIPERIDIN-4-YL]PHENYL}-9H-PURINE	ClC1=CC=C(C=C1)C1(CCNCC1)C1=CC=C(C=C1)C1=C2N=CNC2=NC=N1
PRKACA	DB07857	protein kinase, cAMP-dependent, catalytic, alpha	experimental	(2R)-2-(4-CHLOROPHENYL)-2-[4-(1H-PYRAZOL-4-YL)PHENYL]ETHANAMINE	NC[C@@H](C1=CC=C(Cl)C=C1)C1=CC=C(C=C1)C1=CNN=C1
PRKACA	DB07858	protein kinase, cAMP-dependent, catalytic, alpha	experimental	(2S)-2-(4-CHLOROPHENYL)-2-[4-(1H-PYRAZOL-4-YL)PHENYL]ETHANAMINE	NC[C@H](C1=CC=C(Cl)C=C1)C1=CC=C(C=C1)C1=CNN=C1
PRKACA	DB07859	protein kinase, cAMP-dependent, catalytic, alpha	experimental	4-(4-CHLOROPHENYL)-4-[4-(1H-PYRAZOL-4-YL)PHENYL]PIPERIDINE	ClC1=CC=C(C=C1)C1(CCNCC1)C1=CC=C(C=C1)C1=CNN=C1
PRKACA	DB07860	protein kinase, cAMP-dependent, catalytic, alpha	experimental	(2R)-2-(4-CHLOROPHENYL)-2-PHENYLETHANAMINE	NC[C@H](C1=CC=CC=C1)C1=CC=C(Cl)C=C1
PRKACA	DB07876	protein kinase, cAMP-dependent, catalytic, alpha	experimental	(S)-2-METHYL-1-[(4-METHYL-5-ISOQUINOLINE)SULFONYL]-HOMOPIPERAZINE	C[C@H]1CNCCCN1S(=O)(=O)C1=C2C(C)=CN=CC2=CC=C1
PRKACA	DB07947	protein kinase, cAMP-dependent, catalytic, alpha	experimental	ISOQUINOLINE-5-SULFONIC ACID (2-(2-(4-CHLOROBENZYLOXY)ETHYLAMINO)ETHYL)AMIDE	ClC1=CC=C(COCCNCCNS(=O)(=O)C2=CC=CC3=CN=CC=C23)C=C1
PRKACA	DB07995	protein kinase, cAMP-dependent, catalytic, alpha	experimental	N-[2-(4-BROMOCINNAMYLAMINO)ETHYL]-5-ISOQUINOLINE SULFONAMIDE	BrC1=CC=C(\C=C\CNCCNS(=O)(=O)C2=CC=CC3=C2C=CN=C3)C=C1
PRKACA	DB07996	protein kinase, cAMP-dependent, catalytic, alpha	experimental	1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE	C[C@H]1CNCCN1S(=O)(=O)C1=CC=CC2=C1C=CN=C2
PRKACA	DB07997	protein kinase, cAMP-dependent, catalytic, alpha	experimental	N-[2-(METHYLAMINO)ETHYL]-5-ISOQUINOLINESULFONAMIDE	CNCCNS(=O)(=O)C1=CC=CC2=C1C=CN=C2
PRKACA	DB08070	protein kinase, cAMP-dependent, catalytic, alpha	experimental	2-[4-(3-METHYL-1H-PYRAZOL-4-YL)PHENYL]ETHANAMINE	CC1=NNC=C1C1=CC=C(CCN)C=C1
PRKACA	DB08073	protein kinase, cAMP-dependent, catalytic, alpha	experimental	(2S)-1-(1H-INDOL-3-YL)-3-{[5-(3-METHYL-1H-INDAZOL-5-YL)PYRIDIN-3-YL]OXY}PROPAN-2-AMINE	CC1=NNC2=CC=C(C=C12)C1=CC(OC[C@@H](N)CC2=CNC3=CC=CC=C23)=CN=C1
PRKACA	DB08113	protein kinase, cAMP-dependent, catalytic, alpha	experimental	3-pyridin-4-yl-1H-indazole	N1N=C(C2=C1C=CC=C2)C1=CC=NC=C1
PRKACA	DB08114	protein kinase, cAMP-dependent, catalytic, alpha	experimental	5-benzyl-1,3-thiazol-2-amine	NC1=NC=C(CC2=CC=CC=C2)S1
PRKACA	DB08148	protein kinase, cAMP-dependent, catalytic, alpha	experimental	1-[4-(4-chlorophenyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-yl]methanamine	NCC1(CCN(CC1)C1=C2C=CNC2=NC=N1)C1=CC=C(Cl)C=C1
PRKACA	DB08149	protein kinase, cAMP-dependent, catalytic, alpha	experimental	1-[4-(4-chlorobenzyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-yl]methanamine	NCC1(CC2=CC=C(Cl)C=C2)CCN(CC1)C1=C2C=CNC2=NC=N1
PRKACA	DB08150	protein kinase, cAMP-dependent, catalytic, alpha	experimental	4-(4-chlorobenzyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-aminium	[NH3+]C1(CC2=CC=C(Cl)C=C2)CCN(CC1)C1=C2C=CNC2=NC=N1
PRKACA	DB08162	protein kinase, cAMP-dependent, catalytic, alpha	experimental	5-(1,4-DIAZEPAN-1-SULFONYL)ISOQUINOLINE	O=S(=O)(N1CCCNCC1)C1=CC=CC2=C1C=CN=C2
PRKACA	DB08231	protein kinase, cAMP-dependent, catalytic, alpha	experimental	MYRISTIC ACID	CCCCCCCCCCCCCC(O)=O
PRKACA	DB08568	protein kinase, cAMP-dependent, catalytic, alpha	experimental	(2S)-1-{[5-(3-METHYL-1H-INDAZOL-5-YL)PYRIDIN-3-YL]OXY}-3-PHENYLPROPAN-2-AMINE	CC1=NNC2=CC=C(C=C12)C1=CN=CC(OC[C@@H](N)CC2=CC=CC=C2)=C1
PRKACA	DB08569	protein kinase, cAMP-dependent, catalytic, alpha	experimental	3-PYRIDIN-4-YL-2,4-DIHYDRO-INDENO[1,2-.C.] PYRAZOLE	CC1=NNC2=C1C=C(C=C2)C1=CC(OC[C@@H](N)CC2=CC=C(Br)C=C2)=CN=C1
PRKACA	DB08756	protein kinase, cAMP-dependent, catalytic, alpha	experimental	(R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXANECARBOXAMIDE	C[C@@H](N)[C@H]1CC[C@@H](CC1)C(=O)NC1=CC=NC=C1
PRKACA	DB00938	protein kinase, cAMP-dependent, catalytic, alpha	approved	Salmeterol	OCC1=C(O)C=CC(=C1)C(O)CNCCCCCCOCCCCC1=CC=CC=C1
PRKACA	DB00125	protein kinase, cAMP-dependent, catalytic, alpha	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
PRKACA	DB00435	protein kinase, cAMP-dependent, catalytic, alpha	approved	Nitric Oxide	[N]=O
PRKACA	DB00864	protein kinase, cAMP-dependent, catalytic, alpha	approved; investigational	Tacrolimus	CO[C@@H]1C[C@@H](CC[C@H]1O)\C=C(/C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H]([C@H](C[C@H]2C)OC)[C@H](C[C@@H](C)C\C(C)=C\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]1C)OC
PRKACB	DB00125	protein kinase, cAMP-dependent, catalytic, beta	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
PRKACB	DB00155	protein kinase, cAMP-dependent, catalytic, beta	approved; nutraceutical	L-Citrulline	N[C@@H](CCCNC(N)=O)C(O)=O
PRKACB	DB00435	protein kinase, cAMP-dependent, catalytic, beta	approved	Nitric Oxide	[N]=O
PRKACB	DB00988	protein kinase, cAMP-dependent, catalytic, beta	approved	Dopamine	NCCC1=CC(O)=C(O)C=C1
PRKACB	DB00171	protein kinase, cAMP-dependent, catalytic, beta	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PRKACB	DB00770	protein kinase, cAMP-dependent, catalytic, beta	approved; investigational	Alprostadil	CCCCC[C@H](O)C=C[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(O)=O
PRKACB	DB00668	protein kinase, cAMP-dependent, catalytic, beta	approved	Epinephrine	CNC[C@H](O)C1=CC(O)=C(O)C=C1
PRKACB	DB00131	protein kinase, cAMP-dependent, catalytic, beta	approved; nutraceutical	Adenosine monophosphate	NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PRKACB	DB00396	protein kinase, cAMP-dependent, catalytic, beta	approved	Progesterone	CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C
PRKACB	DB00938	protein kinase, cAMP-dependent, catalytic, beta	approved	Salmeterol	OCC1=C(O)C=CC(=C1)C(O)CNCCCCCCOCCCCC1=CC=CC=C1
PRKACG	DB00125	protein kinase, cAMP-dependent, catalytic, gamma	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
PRKACG	DB00155	protein kinase, cAMP-dependent, catalytic, gamma	approved; nutraceutical	L-Citrulline	N[C@@H](CCCNC(N)=O)C(O)=O
PRKACG	DB00435	protein kinase, cAMP-dependent, catalytic, gamma	approved	Nitric Oxide	[N]=O
PRKACG	DB00988	protein kinase, cAMP-dependent, catalytic, gamma	approved	Dopamine	NCCC1=CC(O)=C(O)C=C1
PRKACG	DB00171	protein kinase, cAMP-dependent, catalytic, gamma	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PRKACG	DB00770	protein kinase, cAMP-dependent, catalytic, gamma	approved; investigational	Alprostadil	CCCCC[C@H](O)C=C[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(O)=O
PRKACG	DB00668	protein kinase, cAMP-dependent, catalytic, gamma	approved	Epinephrine	CNC[C@H](O)C1=CC(O)=C(O)C=C1
PRKACG	DB00131	protein kinase, cAMP-dependent, catalytic, gamma	approved; nutraceutical	Adenosine monophosphate	NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PRKACG	DB00396	protein kinase, cAMP-dependent, catalytic, gamma	approved	Progesterone	CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C
PRKACG	DB00938	protein kinase, cAMP-dependent, catalytic, gamma	approved	Salmeterol	OCC1=C(O)C=CC(=C1)C(O)CNCCCCCCOCCCCC1=CC=CC=C1
PRKAG2	DB00131	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	approved; nutraceutical	Adenosine monophosphate	NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PRKAG2	DB00171	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PRKAG2	DB00412	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	approved; investigational	Rosiglitazone	CN(CCOC1=CC=C(CC2SC(=O)NC2=O)C=C1)C1=CC=CC=N1
PRKAG2	DB01132	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	approved; investigational	Pioglitazone	CCC1=CN=C(CCOC2=CC=C(CC3SC(=O)NC3=O)C=C2)C=C1
PRKAG2	DB00331	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	approved	Metformin	CN(C)C(=N)NC(N)=N
PRKAR1A	DB01790	protein kinase, cAMP-dependent, regulatory, type I, alpha	experimental	Sp-Adenosine-3',5'-Cyclic-Monophosphorothioate	NC1=NC=NC2=C1N=CN2[C@H]1O[C@@H]2CO[P@](O)(=S)O[C@@H]2[C@@H]1O
PRKAR1A	DB02315	protein kinase, cAMP-dependent, regulatory, type I, alpha	experimental	Cyclic Guanosine Monophosphate	NC1=NC2=C(N=CN2[C@H]2O[C@@H]3CO[P@](O)(=O)O[C@@H]3[C@@H]2O)C(=O)N1
PRKAR1A	DB02527	protein kinase, cAMP-dependent, regulatory, type I, alpha	experimental	Cyclic Adenosine Monophosphate	NC1=NC=NC2=C1N=CN2[C@H]1O[C@@H]2CO[P@](O)(=O)O[C@@H]2[C@@H]1O
PRKAR1A	DB00125	protein kinase, cAMP-dependent, regulatory, type I, alpha	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
PRKAR1A	DB00155	protein kinase, cAMP-dependent, regulatory, type I, alpha	approved; nutraceutical	L-Citrulline	N[C@@H](CCCNC(N)=O)C(O)=O
PRKAR1A	DB00435	protein kinase, cAMP-dependent, regulatory, type I, alpha	approved	Nitric Oxide	[N]=O
PRKAR1A	DB00988	protein kinase, cAMP-dependent, regulatory, type I, alpha	approved	Dopamine	NCCC1=CC(O)=C(O)C=C1
PRKAR1A	DB00171	protein kinase, cAMP-dependent, regulatory, type I, alpha	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PRKAR1A	DB00770	protein kinase, cAMP-dependent, regulatory, type I, alpha	approved; investigational	Alprostadil	CCCCC[C@H](O)C=C[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(O)=O
PRKAR1A	DB00668	protein kinase, cAMP-dependent, regulatory, type I, alpha	approved	Epinephrine	CNC[C@H](O)C1=CC(O)=C(O)C=C1
PRKAR1A	DB00131	protein kinase, cAMP-dependent, regulatory, type I, alpha	approved; nutraceutical	Adenosine monophosphate	NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PRKAR1A	DB00396	protein kinase, cAMP-dependent, regulatory, type I, alpha	approved	Progesterone	CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C
PRKAR1B	DB00125	protein kinase, cAMP-dependent, regulatory, type I, beta	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
PRKAR1B	DB00155	protein kinase, cAMP-dependent, regulatory, type I, beta	approved; nutraceutical	L-Citrulline	N[C@@H](CCCNC(N)=O)C(O)=O
PRKAR1B	DB00435	protein kinase, cAMP-dependent, regulatory, type I, beta	approved	Nitric Oxide	[N]=O
PRKAR1B	DB00988	protein kinase, cAMP-dependent, regulatory, type I, beta	approved	Dopamine	NCCC1=CC(O)=C(O)C=C1
PRKAR1B	DB00171	protein kinase, cAMP-dependent, regulatory, type I, beta	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PRKAR1B	DB00770	protein kinase, cAMP-dependent, regulatory, type I, beta	approved; investigational	Alprostadil	CCCCC[C@H](O)C=C[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(O)=O
PRKAR1B	DB00668	protein kinase, cAMP-dependent, regulatory, type I, beta	approved	Epinephrine	CNC[C@H](O)C1=CC(O)=C(O)C=C1
PRKAR1B	DB00131	protein kinase, cAMP-dependent, regulatory, type I, beta	approved; nutraceutical	Adenosine monophosphate	NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PRKAR1B	DB00396	protein kinase, cAMP-dependent, regulatory, type I, beta	approved	Progesterone	CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C
PRKAR2A	DB00125	protein kinase, cAMP-dependent, regulatory, type II, alpha	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
PRKAR2A	DB00155	protein kinase, cAMP-dependent, regulatory, type II, alpha	approved; nutraceutical	L-Citrulline	N[C@@H](CCCNC(N)=O)C(O)=O
PRKAR2A	DB00435	protein kinase, cAMP-dependent, regulatory, type II, alpha	approved	Nitric Oxide	[N]=O
PRKAR2A	DB00988	protein kinase, cAMP-dependent, regulatory, type II, alpha	approved	Dopamine	NCCC1=CC(O)=C(O)C=C1
PRKAR2A	DB00171	protein kinase, cAMP-dependent, regulatory, type II, alpha	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PRKAR2A	DB00770	protein kinase, cAMP-dependent, regulatory, type II, alpha	approved; investigational	Alprostadil	CCCCC[C@H](O)C=C[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(O)=O
PRKAR2A	DB00668	protein kinase, cAMP-dependent, regulatory, type II, alpha	approved	Epinephrine	CNC[C@H](O)C1=CC(O)=C(O)C=C1
PRKAR2A	DB00131	protein kinase, cAMP-dependent, regulatory, type II, alpha	approved; nutraceutical	Adenosine monophosphate	NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PRKAR2A	DB00396	protein kinase, cAMP-dependent, regulatory, type II, alpha	approved	Progesterone	CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C
PRKAR2B	DB00125	protein kinase, cAMP-dependent, regulatory, type II, beta	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
PRKAR2B	DB00155	protein kinase, cAMP-dependent, regulatory, type II, beta	approved; nutraceutical	L-Citrulline	N[C@@H](CCCNC(N)=O)C(O)=O
PRKAR2B	DB00435	protein kinase, cAMP-dependent, regulatory, type II, beta	approved	Nitric Oxide	[N]=O
PRKAR2B	DB00988	protein kinase, cAMP-dependent, regulatory, type II, beta	approved	Dopamine	NCCC1=CC(O)=C(O)C=C1
PRKAR2B	DB00171	protein kinase, cAMP-dependent, regulatory, type II, beta	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PRKAR2B	DB00770	protein kinase, cAMP-dependent, regulatory, type II, beta	approved; investigational	Alprostadil	CCCCC[C@H](O)C=C[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(O)=O
PRKAR2B	DB00668	protein kinase, cAMP-dependent, regulatory, type II, beta	approved	Epinephrine	CNC[C@H](O)C1=CC(O)=C(O)C=C1
PRKAR2B	DB00131	protein kinase, cAMP-dependent, regulatory, type II, beta	approved; nutraceutical	Adenosine monophosphate	NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PRKAR2B	DB00396	protein kinase, cAMP-dependent, regulatory, type II, beta	approved	Progesterone	CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C
PRKCA	DB00144	protein kinase C, alpha	approved; nutraceutical	Phosphatidylserine	CCCC(=O)O[C@H](COC(=O)CC)COP(O)(=O)OC[C@H](N)C(O)=O
PRKCA	DB00163	protein kinase C, alpha	approved; nutraceutical	Vitamin E	CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCC2=C(O1)C(C)=C(C)C(O)=C2C
PRKCA	DB00945	protein kinase C, alpha	approved	Acetylsalicylic acid	CC(=O)OC1=CC=CC=C1C(O)=O
PRKCA	DB00675	protein kinase C, alpha	approved	Tamoxifen	CC\C(=C(/C1=CC=CC=C1)C1=CC=C(OCCN(C)C)C=C1)C1=CC=CC=C1
PRKCA	DB01115	protein kinase C, alpha	approved	Nifedipine	COC(=O)C1=C(C)NC(C)=C(C1C1=CC=CC=C1[N+]([O-])=O)C(=O)OC
PRKCA	DB00877	protein kinase C, alpha	approved; investigational	Sirolimus	CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1O
PRKCA	DB00864	protein kinase C, alpha	approved; investigational	Tacrolimus	CO[C@@H]1C[C@@H](CC[C@H]1O)\C=C(/C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H]([C@H](C[C@H]2C)OC)[C@H](C[C@@H](C)C\C(C)=C\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]1C)OC
PRKCA	DB00608	protein kinase C, alpha	approved	Chloroquine	CCN(CC)CCCC(C)NC1=C2C=CC(Cl)=CC2=NC=C1
PRKCA	DB00171	protein kinase C, alpha	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PRKCA	DB00441	protein kinase C, alpha	approved	Gemcitabine	NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](CO)[C@@H](O)C1(F)F
PRKCA	DB01001	protein kinase C, alpha	approved	Salbutamol	CC(C)(C)NCC(O)C1=CC(CO)=C(O)C=C1
PRKCA	DB00125	protein kinase C, alpha	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
PRKCA	DB00155	protein kinase C, alpha	approved; nutraceutical	L-Citrulline	N[C@@H](CCCNC(N)=O)C(O)=O
PRKCA	DB00435	protein kinase C, alpha	approved	Nitric Oxide	[N]=O
PRKCD	DB04376	protein kinase C, delta	experimental	13-Acetylphorbol	C[C@@H]1[C@@H](O)[C@]2(OC(C)=O)[C@H]([C@@H]3C=C(CO)C[C@@]4(O)[C@@H](C=C(C)C4=O)[C@@]13O)C2(C)C
PRKCD	DB01394	protein kinase C, delta	approved	Colchicine	COC1=C(OC)C(OC)=C2C(CC[C@H](NC(C)=O)C3=CC(=O)C(OC)=CC=C23)=C1
PRKCD	DB00988	protein kinase C, delta	approved	Dopamine	NCCC1=CC(O)=C(O)C=C1
PRKCD	DB00143	protein kinase C, delta	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
PRKCD	DB00125	protein kinase C, delta	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
PRKCD	DB00435	protein kinase C, delta	approved	Nitric Oxide	[N]=O
PRKCD	DB00864	protein kinase C, delta	approved; investigational	Tacrolimus	CO[C@@H]1C[C@@H](CC[C@H]1O)\C=C(/C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H]([C@H](C[C@H]2C)OC)[C@H](C[C@@H](C)C\C(C)=C\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]1C)OC
PROC	DB00170	protein C (inactivator of coagulation factors Va and VIIIa)	approved; nutraceutical	Menadione	CC1=CC(=O)C2=CC=CC=C2C1=O
PROC	DB00464	protein C (inactivator of coagulation factors Va and VIIIa)	approved	Sodium Tetradecyl Sulfate	CCCCCCCCCCCCCCOS(O)(=O)=O
PROC	DB00682	protein C (inactivator of coagulation factors Va and VIIIa)	approved	Warfarin	CC(=O)CC(C1=CC=CC=C1)C1=C(O)OC2=CC=CC=C2C1=O
PRODH	DB00172	proline dehydrogenase (oxidase) 1	approved; nutraceutical	L-Proline	OC(=O)[C@@H]1CCCN1
PROS1	DB00170	protein S (alpha)	approved; nutraceutical	Menadione	CC1=CC(=O)C2=CC=CC=C2C1=O
PROS1	DB00464	protein S (alpha)	approved	Sodium Tetradecyl Sulfate	CCCCCCCCCCCCCCOS(O)(=O)=O
PROS1	DB00682	protein S (alpha)	approved	Warfarin	CC(=O)CC(C1=CC=CC=C1)C1=C(O)OC2=CC=CC=C2C1=O
PROZ	DB00170	protein Z, vitamin K-dependent plasma glycoprotein	approved; nutraceutical	Menadione	CC1=CC(=O)C2=CC=CC=C2C1=O
PROZ	DB00682	protein Z, vitamin K-dependent plasma glycoprotein	approved	Warfarin	CC(=O)CC(C1=CC=CC=C1)C1=C(O)OC2=CC=CC=C2C1=O
PSAT1	DB00114	phosphoserine aminotransferase 1	nutraceutical	Pyridoxal Phosphate	CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O
PSAT1	DB00142	phosphoserine aminotransferase 1	approved; nutraceutical	L-Glutamic Acid	N[C@@H](CCC(O)=O)C(O)=O
PSAT1	DB02327	phosphoserine aminotransferase 1	experimental	2-[2-(2-Hydroxy-Ethoxy)-Ethoxy]-Ethanol	OCCOCCOCCO
PSMA1	DB07475	proteasome (prosome, macropain) subunit, alpha type, 1	experimental	N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE	CC(C)C[C@H](NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)C1=CN=CC=N1)B(O)O
PSMA1	DB08515	proteasome (prosome, macropain) subunit, alpha type, 1	experimental	(3AR,6R,6AS)-6-((S)-((S)-CYCLOHEX-2-ENYL)(HYDROXY)METHYL)-6A-METHYL-4-OXO-HEXAHYDRO-2H-FURO[3,2-C]PYRROLE-6-CARBALDEHYDE	C[C@]12OCC[C@H]1C(=O)N[C@]2(C=O)[C@@H](O)[C@H]1CCCC=C1
PSMA1	DB00171	proteasome (prosome, macropain) subunit, alpha type, 1	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PSMA2	DB07475	proteasome (prosome, macropain) subunit, alpha type, 2	experimental	N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE	CC(C)C[C@H](NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)C1=CN=CC=N1)B(O)O
PSMA2	DB08515	proteasome (prosome, macropain) subunit, alpha type, 2	experimental	(3AR,6R,6AS)-6-((S)-((S)-CYCLOHEX-2-ENYL)(HYDROXY)METHYL)-6A-METHYL-4-OXO-HEXAHYDRO-2H-FURO[3,2-C]PYRROLE-6-CARBALDEHYDE	C[C@]12OCC[C@H]1C(=O)N[C@]2(C=O)[C@@H](O)[C@H]1CCCC=C1
PSMA2	DB00171	proteasome (prosome, macropain) subunit, alpha type, 2	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PSMA3	DB07475	proteasome (prosome, macropain) subunit, alpha type, 3	experimental	N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE	CC(C)C[C@H](NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)C1=CN=CC=N1)B(O)O
PSMA3	DB08515	proteasome (prosome, macropain) subunit, alpha type, 3	experimental	(3AR,6R,6AS)-6-((S)-((S)-CYCLOHEX-2-ENYL)(HYDROXY)METHYL)-6A-METHYL-4-OXO-HEXAHYDRO-2H-FURO[3,2-C]PYRROLE-6-CARBALDEHYDE	C[C@]12OCC[C@H]1C(=O)N[C@]2(C=O)[C@@H](O)[C@H]1CCCC=C1
PSMA3	DB00171	proteasome (prosome, macropain) subunit, alpha type, 3	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PSMA4	DB07475	proteasome (prosome, macropain) subunit, alpha type, 4	experimental	N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE	CC(C)C[C@H](NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)C1=CN=CC=N1)B(O)O
PSMA4	DB08515	proteasome (prosome, macropain) subunit, alpha type, 4	experimental	(3AR,6R,6AS)-6-((S)-((S)-CYCLOHEX-2-ENYL)(HYDROXY)METHYL)-6A-METHYL-4-OXO-HEXAHYDRO-2H-FURO[3,2-C]PYRROLE-6-CARBALDEHYDE	C[C@]12OCC[C@H]1C(=O)N[C@]2(C=O)[C@@H](O)[C@H]1CCCC=C1
PSMA4	DB00171	proteasome (prosome, macropain) subunit, alpha type, 4	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PSMA5	DB07475	proteasome (prosome, macropain) subunit, alpha type, 5	experimental	N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE	CC(C)C[C@H](NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)C1=CN=CC=N1)B(O)O
PSMA5	DB08515	proteasome (prosome, macropain) subunit, alpha type, 5	experimental	(3AR,6R,6AS)-6-((S)-((S)-CYCLOHEX-2-ENYL)(HYDROXY)METHYL)-6A-METHYL-4-OXO-HEXAHYDRO-2H-FURO[3,2-C]PYRROLE-6-CARBALDEHYDE	C[C@]12OCC[C@H]1C(=O)N[C@]2(C=O)[C@@H](O)[C@H]1CCCC=C1
PSMA5	DB00171	proteasome (prosome, macropain) subunit, alpha type, 5	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PSMA6	DB07475	proteasome (prosome, macropain) subunit, alpha type, 6	experimental	N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE	CC(C)C[C@H](NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)C1=CN=CC=N1)B(O)O
PSMA6	DB08515	proteasome (prosome, macropain) subunit, alpha type, 6	experimental	(3AR,6R,6AS)-6-((S)-((S)-CYCLOHEX-2-ENYL)(HYDROXY)METHYL)-6A-METHYL-4-OXO-HEXAHYDRO-2H-FURO[3,2-C]PYRROLE-6-CARBALDEHYDE	C[C@]12OCC[C@H]1C(=O)N[C@]2(C=O)[C@@H](O)[C@H]1CCCC=C1
PSMA6	DB00171	proteasome (prosome, macropain) subunit, alpha type, 6	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PSMA7	DB07475	proteasome (prosome, macropain) subunit, alpha type, 7	experimental	N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE	CC(C)C[C@H](NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)C1=CN=CC=N1)B(O)O
PSMA7	DB07558	proteasome (prosome, macropain) subunit, alpha type, 7	experimental	2-ACETYLAMINO-4-METHYL-PENTANOIC ACID [1-(1-FORMYL-PENTYLCARBAMOYL)-3-METHYL-BUTYL]-AMIDE	CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(C)=O)C=O
PSMA7	DB08515	proteasome (prosome, macropain) subunit, alpha type, 7	experimental	(3AR,6R,6AS)-6-((S)-((S)-CYCLOHEX-2-ENYL)(HYDROXY)METHYL)-6A-METHYL-4-OXO-HEXAHYDRO-2H-FURO[3,2-C]PYRROLE-6-CARBALDEHYDE	C[C@]12OCC[C@H]1C(=O)N[C@]2(C=O)[C@@H](O)[C@H]1CCCC=C1
PSMA7	DB00171	proteasome (prosome, macropain) subunit, alpha type, 7	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PSMB1	DB00188	proteasome (prosome, macropain) subunit, beta type, 1	approved; investigational	Bortezomib	CC(C)C[C@@H](NC(=O)[C@@H](CC1=CC=CC=C1)NC(=O)C1=NC=CN=C1)B(O)O
PSMB1	DB07475	proteasome (prosome, macropain) subunit, beta type, 1	experimental	N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE	CC(C)C[C@H](NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)C1=CN=CC=N1)B(O)O
PSMB1	DB08515	proteasome (prosome, macropain) subunit, beta type, 1	experimental	(3AR,6R,6AS)-6-((S)-((S)-CYCLOHEX-2-ENYL)(HYDROXY)METHYL)-6A-METHYL-4-OXO-HEXAHYDRO-2H-FURO[3,2-C]PYRROLE-6-CARBALDEHYDE	C[C@]12OCC[C@H]1C(=O)N[C@]2(C=O)[C@@H](O)[C@H]1CCCC=C1
PSMB1	DB00171	proteasome (prosome, macropain) subunit, beta type, 1	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PSMB2	DB00188	proteasome (prosome, macropain) subunit, beta type, 2	approved; investigational	Bortezomib	CC(C)C[C@@H](NC(=O)[C@@H](CC1=CC=CC=C1)NC(=O)C1=NC=CN=C1)B(O)O
PSMB2	DB07475	proteasome (prosome, macropain) subunit, beta type, 2	experimental	N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE	CC(C)C[C@H](NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)C1=CN=CC=N1)B(O)O
PSMB2	DB08515	proteasome (prosome, macropain) subunit, beta type, 2	experimental	(3AR,6R,6AS)-6-((S)-((S)-CYCLOHEX-2-ENYL)(HYDROXY)METHYL)-6A-METHYL-4-OXO-HEXAHYDRO-2H-FURO[3,2-C]PYRROLE-6-CARBALDEHYDE	C[C@]12OCC[C@H]1C(=O)N[C@]2(C=O)[C@@H](O)[C@H]1CCCC=C1
PSMB2	DB00171	proteasome (prosome, macropain) subunit, beta type, 2	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PSMB3	DB07475	proteasome (prosome, macropain) subunit, beta type, 3	experimental	N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE	CC(C)C[C@H](NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)C1=CN=CC=N1)B(O)O
PSMB3	DB08515	proteasome (prosome, macropain) subunit, beta type, 3	experimental	(3AR,6R,6AS)-6-((S)-((S)-CYCLOHEX-2-ENYL)(HYDROXY)METHYL)-6A-METHYL-4-OXO-HEXAHYDRO-2H-FURO[3,2-C]PYRROLE-6-CARBALDEHYDE	C[C@]12OCC[C@H]1C(=O)N[C@]2(C=O)[C@@H](O)[C@H]1CCCC=C1
PSMB3	DB00171	proteasome (prosome, macropain) subunit, beta type, 3	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PSMB4	DB07475	proteasome (prosome, macropain) subunit, beta type, 4	experimental	N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE	CC(C)C[C@H](NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)C1=CN=CC=N1)B(O)O
PSMB4	DB08515	proteasome (prosome, macropain) subunit, beta type, 4	experimental	(3AR,6R,6AS)-6-((S)-((S)-CYCLOHEX-2-ENYL)(HYDROXY)METHYL)-6A-METHYL-4-OXO-HEXAHYDRO-2H-FURO[3,2-C]PYRROLE-6-CARBALDEHYDE	C[C@]12OCC[C@H]1C(=O)N[C@]2(C=O)[C@@H](O)[C@H]1CCCC=C1
PSMB4	DB00171	proteasome (prosome, macropain) subunit, beta type, 4	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PSMB4	DB01151	proteasome (prosome, macropain) subunit, beta type, 4	approved	Desipramine	CNCCCN1C2=CC=CC=C2CCC2=CC=CC=C12
PSMB4	DB00472	proteasome (prosome, macropain) subunit, beta type, 4	approved	Fluoxetine	CNCCC(OC1=CC=C(C=C1)C(F)(F)F)C1=CC=CC=C1
PSMB5	DB00188	proteasome (prosome, macropain) subunit, beta type, 5	approved; investigational	Bortezomib	CC(C)C[C@@H](NC(=O)[C@@H](CC1=CC=CC=C1)NC(=O)C1=NC=CN=C1)B(O)O
PSMB5	DB07475	proteasome (prosome, macropain) subunit, beta type, 5	experimental	N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE	CC(C)C[C@H](NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)C1=CN=CC=N1)B(O)O
PSMB5	DB08515	proteasome (prosome, macropain) subunit, beta type, 5	experimental	(3AR,6R,6AS)-6-((S)-((S)-CYCLOHEX-2-ENYL)(HYDROXY)METHYL)-6A-METHYL-4-OXO-HEXAHYDRO-2H-FURO[3,2-C]PYRROLE-6-CARBALDEHYDE	C[C@]12OCC[C@H]1C(=O)N[C@]2(C=O)[C@@H](O)[C@H]1CCCC=C1
PSMB5	DB00171	proteasome (prosome, macropain) subunit, beta type, 5	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PSMB6	DB07475	proteasome (prosome, macropain) subunit, beta type, 6	experimental	N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE	CC(C)C[C@H](NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)C1=CN=CC=N1)B(O)O
PSMB6	DB08515	proteasome (prosome, macropain) subunit, beta type, 6	experimental	(3AR,6R,6AS)-6-((S)-((S)-CYCLOHEX-2-ENYL)(HYDROXY)METHYL)-6A-METHYL-4-OXO-HEXAHYDRO-2H-FURO[3,2-C]PYRROLE-6-CARBALDEHYDE	C[C@]12OCC[C@H]1C(=O)N[C@]2(C=O)[C@@H](O)[C@H]1CCCC=C1
PSMB6	DB00171	proteasome (prosome, macropain) subunit, beta type, 6	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PSMB7	DB07475	proteasome (prosome, macropain) subunit, beta type, 7	experimental	N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE	CC(C)C[C@H](NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)C1=CN=CC=N1)B(O)O
PSMB7	DB08515	proteasome (prosome, macropain) subunit, beta type, 7	experimental	(3AR,6R,6AS)-6-((S)-((S)-CYCLOHEX-2-ENYL)(HYDROXY)METHYL)-6A-METHYL-4-OXO-HEXAHYDRO-2H-FURO[3,2-C]PYRROLE-6-CARBALDEHYDE	C[C@]12OCC[C@H]1C(=O)N[C@]2(C=O)[C@@H](O)[C@H]1CCCC=C1
PSMB7	DB00171	proteasome (prosome, macropain) subunit, beta type, 7	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PSMC4	DB00877	proteasome (prosome, macropain) 26S subunit, ATPase, 4	approved; investigational	Sirolimus	CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1O
PSMD1	DB00188	proteasome (prosome, macropain) 26S subunit, non-ATPase, 1	approved; investigational	Bortezomib	CC(C)C[C@@H](NC(=O)[C@@H](CC1=CC=CC=C1)NC(=O)C1=NC=CN=C1)B(O)O
PSMD11	DB00171	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PSMD12	DB00171	proteasome (prosome, macropain) 26S subunit, non-ATPase, 12	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PSMD14	DB03247	proteasome (prosome, macropain) 26S subunit, non-ATPase, 14	experimental	Riboflavin Monophosphate	CC1=CC2=C(C=C1C)N(C[C@@H](O)[C@@H](O)[C@H](O)COP(O)(O)=O)C1=NC(=O)NC(=O)C1=N2
PSMD14	DB00171	proteasome (prosome, macropain) 26S subunit, non-ATPase, 14	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PSMD2	DB00188	proteasome (prosome, macropain) 26S subunit, non-ATPase, 2	approved; investigational	Bortezomib	CC(C)C[C@@H](NC(=O)[C@@H](CC1=CC=CC=C1)NC(=O)C1=NC=CN=C1)B(O)O
PSMD3	DB00171	proteasome (prosome, macropain) 26S subunit, non-ATPase, 3	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PSMD4	DB00171	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PTDSS1	DB00144	phosphatidylserine synthase 1	approved; nutraceutical	Phosphatidylserine	CCCC(=O)O[C@H](COC(=O)CC)COP(O)(=O)OC[C@H](N)C(O)=O
PTDSS2	DB00144	phosphatidylserine synthase 2	approved; nutraceutical	Phosphatidylserine	CCCC(=O)O[C@H](COC(=O)CC)COP(O)(=O)OC[C@H](N)C(O)=O
PTEN	DB00877	phosphatase and tensin homolog	approved; investigational	Sirolimus	CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1O
PTEN	DB00619	phosphatase and tensin homolog	approved	Imatinib	CN1CCN(CC2=CC=C(C=C2)C(=O)NC2=CC(NC3=NC=CC(=N3)C3=CN=CC=C3)=C(C)C=C2)CC1
PTEN	DB00201	phosphatase and tensin homolog	approved	Caffeine	CN1C=NC2=C1C(=O)N(C)C(=O)N2C
PTEN	DB00515	phosphatase and tensin homolog	approved	Cisplatin	N[Pt](N)(Cl)Cl
PTEN	DB01248	phosphatase and tensin homolog	approved; investigational	Docetaxel	CC(=O)O[C@@]12CO[C@@H]1C[C@H](O)[C@]1(C)[C@@H]2[C@H](OC(=O)C2=CC=CC=C2)[C@]2(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C3=CC=CC=C3)C(C)=C([C@@H](O)C1=O)C2(C)C
PTEN	DB00544	phosphatase and tensin homolog	approved	Fluorouracil	FC1=CNC(=O)NC1=O
PTEN	DB00650	phosphatase and tensin homolog	approved	Leucovorin	NC1=NC(=O)C2=C(NCC(CNC3=CC=C(C=C3)C(=O)N[C@H](CCC(O)=O)C(O)=O)N2C=O)N1
PTEN	DB00848	phosphatase and tensin homolog	approved	Levamisole	C1CN2C[C@@H](N=C2S1)C1=CC=CC=C1
PTEN	DB01132	phosphatase and tensin homolog	approved; investigational	Pioglitazone	CCC1=CN=C(CCOC2=CC=C(CC3SC(=O)NC3=O)C=C2)C=C1
PTEN	DB00412	phosphatase and tensin homolog	approved; investigational	Rosiglitazone	CN(CCOC1=CC=C(CC2SC(=O)NC2=O)C=C1)C1=CC=CC=N1
PTGDS	DB00482	prostaglandin D2 synthase 21kDa (brain)	approved; investigational	Celecoxib	CC1=CC=C(C=C1)C1=CC(=NN1C1=CC=C(C=C1)S(N)(=O)=O)C(F)(F)F
PTGES	DB00917	prostaglandin E synthase	approved	Dinoprostone	CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O
PTGES	DB01240	prostaglandin E synthase	approved	Epoprostenol	CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)C[C@@H]2OC(C[C@H]12)=CCCCC(O)=O
PTGES	DB00482	prostaglandin E synthase	approved; investigational	Celecoxib	CC1=CC=C(C=C1)C1=CC(=NN1C1=CC=C(C=C1)S(N)(=O)=O)C(F)(F)F
PTGIS	DB00812	prostaglandin I2 (prostacyclin) synthase	approved	Phenylbutazone	CCCCC1C(=O)N(N(C1=O)C1=CC=CC=C1)C1=CC=CC=C1
PTGIS	DB01240	prostaglandin I2 (prostacyclin) synthase	approved	Epoprostenol	CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)C[C@@H]2OC(C[C@H]12)=CCCCC(O)=O
PTGIS	DB08675	prostaglandin I2 (prostacyclin) synthase	experimental	(6E)-7-{6-[(1E)-OCT-1-ENYL]-2,3-DIAZABICYCLO[2.2.1]HEPT-2-EN-5-YL}HEPT-6-ENOIC ACID	CCCCCC\C=C\[C@H]1[C@H]2C[C@H](N=N2)[C@@H]1\C=C\CCCCC(O)=O
PTGIS	DB00564	prostaglandin I2 (prostacyclin) synthase	approved; investigational	Carbamazepine	NC(=O)N1C2=CC=CC=C2C=CC2=CC=CC=C12
PTGIS	DB00252	prostaglandin I2 (prostacyclin) synthase	approved	Phenytoin	O=C1NC(=O)C(N1)(C1=CC=CC=C1)C1=CC=CC=C1
PTGIS	DB00917	prostaglandin I2 (prostacyclin) synthase	approved	Dinoprostone	CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O
PTGIS	DB00482	prostaglandin I2 (prostacyclin) synthase	approved; investigational	Celecoxib	CC1=CC=C(C=C1)C1=CC(=NN1C1=CC=C(C=C1)S(N)(=O)=O)C(F)(F)F
PTGS1	DB00154	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	approved; nutraceutical	gamma-Homolinolenic acid	CCCCC\C=C/C\C=C/C\C=C/CCCCCCC(O)=O
PTGS1	DB00159	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	approved; nutraceutical	Icosapent	CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O
PTGS1	DB00244	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	approved	Mesalazine	NC1=CC(C(O)=O)=C(O)C=C1
PTGS1	DB00316	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	approved	Acetaminophen	CC(=O)NC1=CC=C(O)C=C1
PTGS1	DB00328	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	approved; investigational	Indomethacin	COC1=CC2=C(C=C1)N(C(=O)C1=CC=C(Cl)C=C1)C(C)=C2CC(O)=O
PTGS1	DB00350	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	approved	Minoxidil	NC1=CC(=NC(N)=[N+]1[O-])N1CCCCC1
PTGS1	DB00461	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	approved	Nabumetone	COC1=CC2=C(C=C1)C=C(CCC(C)=O)C=C2
PTGS1	DB00465	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	approved	Ketorolac	OC(=O)C1CCN2C1=CC=C2C(=O)C1=CC=CC=C1
PTGS1	DB00469	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	approved	Tenoxicam	CN1\C(=C(/O)NC2=CC=CC=N2)C(=O)C2=C(C=CS2)S1(=O)=O
PTGS1	DB00500	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	approved	Tolmetin	CN1C(CC(O)=O)=CC=C1C(=O)C1=CC=C(C)C=C1
PTGS1	DB00554	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	approved; investigational	Piroxicam	CN1\C(=C(\O)NC2=CC=CC=N2)C(=O)C2=CC=CC=C2S1(=O)=O
PTGS1	DB00573	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	approved	Fenoprofen	CC(C(O)=O)C1=CC(OC2=CC=CC=C2)=CC=C1
PTGS1	DB00586	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	approved	Diclofenac	OC(=O)CC1=CC=CC=C1NC1=C(Cl)C=CC=C1Cl
PTGS1	DB00605	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	approved	Sulindac	CC1=C(CC(O)=O)C2=C(C=CC(F)=C2)C1=CC1=CC=C(C=C1)S(C)=O
PTGS1	DB00711	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	approved	Diethylcarbamazine	CCN(CC)C(=O)N1CCN(C)CC1
PTGS1	DB00712	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	approved	Flurbiprofen	CC(C(O)=O)C1=CC(F)=C(C=C1)C1=CC=CC=C1
PTGS1	DB00749	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	approved; investigational	Etodolac	CCC1=C2NC3=C(CCOC3(CC)CC(O)=O)C2=CC=C1
PTGS1	DB00784	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	approved	Mefenamic acid	CC1=C(C)C(NC2=CC=CC=C2C(O)=O)=CC=C1
PTGS1	DB00788	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	approved	Naproxen	COC1=CC2=C(C=C1)C=C(C=C2)C(C)C(O)=O
PTGS1	DB00795	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	approved	Sulfasalazine	OC(=O)C1=CC(=CC=C1O)\N=N\C1=CC=C(C=C1)S(=O)(=O)NC1=NC=CC=C1
PTGS1	DB00812	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	approved	Phenylbutazone	CCCCC1C(=O)N(N(C1=O)C1=CC=CC=C1)C1=CC=CC=C1
PTGS1	DB00814	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	approved	Meloxicam	CN1C(C(=O)NC2=NC=C(C)S2)=C(O)C2=C(C=CC=C2)S1(=O)=O
PTGS1	DB00821	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	approved	Carprofen	CC(C(O)=O)C1=CC2=C(C=C1)C1=C(N2)C=CC(Cl)=C1
PTGS1	DB00861	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	approved	Diflunisal	OC(=O)C1=C(O)C=CC(=C1)C1=C(F)C=C(F)C=C1
PTGS1	DB00870	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	approved	Suprofen	CC(C(O)=O)C1=CC=C(C=C1)C(=O)C1=CC=CS1
PTGS1	DB00936	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	approved	Salicyclic acid	OC(=O)C1=CC=CC=C1O
PTGS1	DB00939	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	approved	Meclofenamic acid	CC1=C(Cl)C(NC2=CC=CC=C2C(O)=O)=C(Cl)C=C1
PTGS1	DB00945	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	approved	Acetylsalicylic acid	CC(=O)OC1=CC=CC=C1C(O)=O
PTGS1	DB00963	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	approved	Bromfenac	NC1=C(CC(O)=O)C=CC=C1C(=O)C1=CC=C(Br)C=C1
PTGS1	DB00991	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	approved	Oxaprozin	OC(=O)CCC1=NC(=C(O1)C1=CC=CC=C1)C1=CC=CC=C1
PTGS1	DB01009	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	approved	Ketoprofen	CC(C(O)=O)C1=CC(=CC=C1)C(=O)C1=CC=CC=C1
PTGS1	DB01014	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	approved; investigational	Balsalazide	OC(=O)CCNC(=O)C1=CC=C(N\N=C2\C=CC(=O)C(=C2)C(O)=O)C=C1
PTGS1	DB01050	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	approved	Ibuprofen	CC(C)CC1=CC=C(C=C1)C(C)C(O)=O
PTGS1	DB01283	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	approved; investigational	Lumiracoxib	CC1=CC(CC(O)=O)=C(NC2=C(F)C=CC=C2Cl)C=C1
PTGS1	DB01294	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	approved	Bismuth Subsalicylate	O[Bi]1OC(=O)C2=CC=CC=C2O1
PTGS1	DB01397	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	approved	Magnesium salicylate	[Mg++].OC1=CC=CC=C1C([O-])=O.OC1=CC=CC=C1C([O-])=O
PTGS1	DB01398	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	approved	Salicylate-sodium	[Na+].OC1=CC=CC=C1C([O-])=O
PTGS1	DB01399	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	approved	Salsalate	OC(=O)C1=CC=CC=C1OC(=O)C1=CC=CC=C1O
PTGS1	DB01401	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	approved	Trisalicylate-choline	[Mg++].C[N+](C)(C)CCO.OC(=O)C1=CC=CC=C1O.OC1=CC=CC=C1C([O-])=O
PTGS1	DB01419	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	approved	Antrafenine	FC(F)(F)C1=CC(=CC=C1)N1CCN(CCOC(=O)C2=CC=CC=C2NC2=C3C=CC(=CC3=NC=C2)C(F)(F)F)CC1
PTGS1	DB01435	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	approved	Antipyrine	CN1N(C(=O)C=C1C)C1=CC=CC=C1
PTGS1	DB01600	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	approved	Tiaprofenic acid	CC(C(O)=O)C1=CC=C(S1)C(=O)C1=CC=CC=C1
PTGS1	DB01837	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	experimental	O-Acetylserine	CC(=O)OC[C@@H](N)C(O)=O
PTGS1	DB01892	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	nutraceutical	Hyperforin	CC(C)C(=O)C12C(O)=C(CC=C(C)C)C(=O)C(CC=C(C)C)(CC(CC=C(C)C)C1(C)CCC=C(C)C)C2=O
PTGS1	DB02047	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	experimental	2-(1,1'-Biphenyl-4-Yl)Propanoic Acid	C[C@H](C(O)=O)C1=CC=C(C=C1)C1=CC=CC=C1
PTGS1	DB02110	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	experimental	Protoporphyrin Ix Containing Co	CC1=C(C=C)C2=CC3=[N+]4C(=CC5=C(C)C(CCC(O)=O)=C6C=C7C(CCC(O)=O)=C(C)C8=[N+]7[Co@]4(N2C1=C8)N56)C(C=C)=C3C
PTGS1	DB02198	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	experimental	2-Bromoacetyl Group	OC(=O)CBr
PTGS1	DB02266	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	experimental	Flufenamic Acid	OC(=O)C1=CC=CC=C1NC1=CC(=CC=C1)C(F)(F)F
PTGS1	DB02379	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	experimental	Beta-D-Glucose	OC[C@@H]1O[C@H](O)[C@@H](O)[C@H](O)[C@H]1O
PTGS1	DB02687	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	experimental	Beta-D-Mannose	OC[C@@H]1O[C@H](O)[C@@H](O)[C@H](O)[C@H]1O
PTGS1	DB02709	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	experimental; investigational	Resveratrol	OC1=CC=C(\C=C\C2=CC(O)=CC(O)=C2)C=C1
PTGS1	DB02773	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	experimental	(3-Chloro-4-Propoxy-Phenyl)-Acetic Acid	CCCOC1=CC=C(CC(O)=O)C=C1Cl
PTGS1	DB02944	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	experimental	Alpha-D-Mannose	OC[C@@H]1O[C@H](O)[C@@H](O)[C@H](O)[C@H]1O
PTGS1	DB03014	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	experimental	Heme	CC1=C(CCC(O)=O)C2=CC3=[N+]4C(=CC5=C(C=C)C(C)=C6C=C7C(C=C)=C(C)C8=[N+]7[Fe@]4(N2C1=C8)N56)C(C)=C3CCC(O)=O
PTGS1	DB03667	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	experimental	Acetic Acid Salicyloyl-Amino-Ester	CC(=O)ONC(=O)C1=C(O)C=CC=C1
PTGS1	DB03752	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	experimental	P-(2'-Iodo-5'-Thenoyl)Hydrotropic Acid	C[C@H](C(O)=O)C1=CC=C(C=C1)C(=O)C1=CC=C(I)S1
PTGS1	DB03753	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	experimental	Flurbiprofen Methyl Ester	COC(=O)[C@@H](C)C1=CC=C(C(F)=C1)C1=CC=CC=C1
PTGS1	DB03783	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	experimental; withdrawn	Phenacetin	CCOC1=CC=C(NC(C)=O)C=C1
PTGS1	DB04552	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	approved	Niflumic Acid	OC(=O)C1=C(NC2=CC=CC(=C2)C(F)(F)F)N=CC=C1
PTGS1	DB04557	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	experimental	Arachidonic Acid	CCCCC\C=C\C\C=C\C\C=C\C\C=C\CCCC(O)=O
PTGS1	DB04817	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	withdrawn	Dipyrone	[Na+].CN(CS([O-])(=O)=O)C1=C(C)N(C)N(C1=O)C1=CC=CC=C1
PTGS1	DB06725	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	approved	Lornoxicam	CN1\C(=C(\O)NC2=CC=CC=N2)C(=O)C2=C(C=C(Cl)S2)S1(=O)=O
PTGS1	DB06802	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	approved	Nepafenac	NC(=O)CC1=CC=CC(C(=O)C2=CC=CC=C2)=C1N
PTGS1	DB07981	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	experimental	2-[1-(4-CHLOROBENZOYL)-5-METHOXY-2-METHYL-1H-INDOL-3-YL]-N-[(1R)-1-(HYDROXYMETHYL)PROPYL]ACETAMIDE	CC[C@H](CO)NC(=O)CC1=C(C)N(C(=O)C2=CC=C(Cl)C=C2)C2=CC=C(OC)C=C12
PTGS1	DB07983	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	experimental	1-(4-IODOBENZOYL)-5-METHOXY-2-METHYL INDOLE-3-ACETIC ACID	COC1=CC=C2N(C(=O)C3=CC=C(I)C=C3)C(C)=C(CC(O)=O)C2=C1
PTGS1	DB07984	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	experimental	2-[1-(4-CHLOROBENZOYL)-5-METHOXY-2-METHYL-1H-INDOL-3-YL]-N-[(1S)-1-(HYDROXYMETHYL)PROPYL]ACETAMIDE	CC[C@@H](CO)NC(=O)CC1=C(C)N(C(=O)C2=CC=C(Cl)C=C2)C2=C1C=C(OC)C=C2
PTGS1	DB00532	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	approved	Mephenytoin	CCC1(NC(=O)N(C)C1=O)C1=CC=CC=C1
PTGS1	DB01174	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	approved	Phenobarbital	CCC1(C(=O)NC(=O)NC1=O)C1=CC=CC=C1
PTGS1	DB00252	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	approved	Phenytoin	O=C1NC(=O)C(N1)(C1=CC=CC=C1)C1=CC=CC=C1
PTGS1	DB00347	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	approved	Trimethadione	CN1C(=O)OC(C)(C)C1=O
PTGS1	DB00917	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	approved	Dinoprostone	CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O
PTGS1	DB01240	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	approved	Epoprostenol	CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)C[C@@H]2OC(C[C@H]12)=CCCCC(O)=O
PTGS1	DB00482	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	approved; investigational	Celecoxib	CC1=CC=C(C=C1)C1=CC(=NN1C1=CC=C(C=C1)S(N)(=O)=O)C(F)(F)F
PTGS2	DB00154	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved; nutraceutical	gamma-Homolinolenic acid	CCCCC\C=C/C\C=C/C\C=C/CCCCCCC(O)=O
PTGS2	DB00159	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved; nutraceutical	Icosapent	CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O
PTGS2	DB00233	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved	Aminosalicylic Acid	NC1=CC(O)=C(C=C1)C(O)=O
PTGS2	DB00244	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved	Mesalazine	NC1=CC(C(O)=O)=C(O)C=C1
PTGS2	DB00316	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved	Acetaminophen	CC(=O)NC1=CC=C(O)C=C1
PTGS2	DB00328	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved; investigational	Indomethacin	COC1=CC2=C(C=C1)N(C(=O)C1=CC=C(Cl)C=C1)C(C)=C2CC(O)=O
PTGS2	DB00461	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved	Nabumetone	COC1=CC2=C(C=C1)C=C(CCC(C)=O)C=C2
PTGS2	DB00465	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved	Ketorolac	OC(=O)C1CCN2C1=CC=C2C(=O)C1=CC=CC=C1
PTGS2	DB00469	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved	Tenoxicam	CN1\C(=C(/O)NC2=CC=CC=N2)C(=O)C2=C(C=CS2)S1(=O)=O
PTGS2	DB00480	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved; investigational	Lenalidomide	NC1=CC=CC2=C1CN(C1CCC(=O)NC1=O)C2=O
PTGS2	DB00482	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved; investigational	Celecoxib	CC1=CC=C(C=C1)C1=CC(=NN1C1=CC=C(C=C1)S(N)(=O)=O)C(F)(F)F
PTGS2	DB00500	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved	Tolmetin	CN1C(CC(O)=O)=CC=C1C(=O)C1=CC=C(C)C=C1
PTGS2	DB00533	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	withdrawn; investigational	Rofecoxib	CS(=O)(=O)C1=CC=C(C=C1)C1=C(C(=O)OC1)C1=CC=CC=C1
PTGS2	DB00554	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved; investigational	Piroxicam	CN1\C(=C(\O)NC2=CC=CC=N2)C(=O)C2=CC=CC=C2S1(=O)=O
PTGS2	DB00573	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved	Fenoprofen	CC(C(O)=O)C1=CC(OC2=CC=CC=C2)=CC=C1
PTGS2	DB00580	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	withdrawn; investigational	Valdecoxib	CC1=C(C(=NO1)C1=CC=CC=C1)C1=CC=C(C=C1)S(N)(=O)=O
PTGS2	DB00586	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved	Diclofenac	OC(=O)CC1=CC=CC=C1NC1=C(Cl)C=CC=C1Cl
PTGS2	DB00605	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved	Sulindac	CC1=C(CC(O)=O)C2=C(C=CC(F)=C2)C1=CC1=CC=C(C=C1)S(C)=O
PTGS2	DB00712	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved	Flurbiprofen	CC(C(O)=O)C1=CC(F)=C(C=C1)C1=CC=CC=C1
PTGS2	DB00749	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved; investigational	Etodolac	CCC1=C2NC3=C(CCOC3(CC)CC(O)=O)C2=CC=C1
PTGS2	DB00784	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved	Mefenamic acid	CC1=C(C)C(NC2=CC=CC=C2C(O)=O)=CC=C1
PTGS2	DB00788	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved	Naproxen	COC1=CC2=C(C=C1)C=C(C=C2)C(C)C(O)=O
PTGS2	DB00795	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved	Sulfasalazine	OC(=O)C1=CC(=CC=C1O)\N=N\C1=CC=C(C=C1)S(=O)(=O)NC1=NC=CC=C1
PTGS2	DB00812	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved	Phenylbutazone	CCCCC1C(=O)N(N(C1=O)C1=CC=CC=C1)C1=CC=CC=C1
PTGS2	DB00814	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved	Meloxicam	CN1C(C(=O)NC2=NC=C(C)S2)=C(O)C2=C(C=CC=C2)S1(=O)=O
PTGS2	DB00821	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved	Carprofen	CC(C(O)=O)C1=CC2=C(C=C1)C1=C(N2)C=CC(Cl)=C1
PTGS2	DB00861	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved	Diflunisal	OC(=O)C1=C(O)C=CC(=C1)C1=C(F)C=C(F)C=C1
PTGS2	DB00870	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved	Suprofen	CC(C(O)=O)C1=CC=C(C=C1)C(=O)C1=CC=CS1
PTGS2	DB00936	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved	Salicyclic acid	OC(=O)C1=CC=CC=C1O
PTGS2	DB00939	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved	Meclofenamic acid	CC1=C(Cl)C(NC2=CC=CC=C2C(O)=O)=C(Cl)C=C1
PTGS2	DB00945	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved	Acetylsalicylic acid	CC(=O)OC1=CC=CC=C1C(O)=O
PTGS2	DB00963	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved	Bromfenac	NC1=C(CC(O)=O)C=CC=C1C(=O)C1=CC=C(Br)C=C1
PTGS2	DB00991	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved	Oxaprozin	OC(=O)CCC1=NC(=C(O1)C1=CC=CC=C1)C1=CC=CC=C1
PTGS2	DB01009	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved	Ketoprofen	CC(C(O)=O)C1=CC(=CC=C1)C(=O)C1=CC=CC=C1
PTGS2	DB01014	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved; investigational	Balsalazide	OC(=O)CCNC(=O)C1=CC=C(N\N=C2\C=CC(=O)C(=C2)C(O)=O)C=C1
PTGS2	DB01041	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved; withdrawn; investigational	Thalidomide	O=C1N(C2CCC(=O)NC2=O)C(=O)C2=CC=CC=C12
PTGS2	DB01050	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved	Ibuprofen	CC(C)CC1=CC=C(C=C1)C(C)C(O)=O
PTGS2	DB01283	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved; investigational	Lumiracoxib	CC1=CC(CC(O)=O)=C(NC2=C(F)C=CC=C2Cl)C=C1
PTGS2	DB01294	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved	Bismuth Subsalicylate	O[Bi]1OC(=O)C2=CC=CC=C2O1
PTGS2	DB01397	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved	Magnesium salicylate	[Mg++].OC1=CC=CC=C1C([O-])=O.OC1=CC=CC=C1C([O-])=O
PTGS2	DB01398	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved	Salicylate-sodium	[Na+].OC1=CC=CC=C1C([O-])=O
PTGS2	DB01399	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved	Salsalate	OC(=O)C1=CC=CC=C1OC(=O)C1=CC=CC=C1O
PTGS2	DB01401	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved	Trisalicylate-choline	[Mg++].C[N+](C)(C)CCO.OC(=O)C1=CC=CC=C1O.OC1=CC=CC=C1C([O-])=O
PTGS2	DB01419	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved	Antrafenine	FC(F)(F)C1=CC(=CC=C1)N1CCN(CCOC(=O)C2=CC=CC=C2NC2=C3C=CC(=CC3=NC=C2)C(F)(F)F)CC1
PTGS2	DB01435	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved	Antipyrine	CN1N(C(=O)C=C1C)C1=CC=CC=C1
PTGS2	DB01600	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved	Tiaprofenic acid	CC(C(O)=O)C1=CC=C(S1)C(=O)C1=CC=CC=C1
PTGS2	DB01628	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved; investigational	Etoricoxib	CC1=NC=C(C=C1)C1=C(C=C(Cl)C=N1)C1=CC=C(C=C1)S(C)(=O)=O
PTGS2	DB02266	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	experimental	Flufenamic Acid	OC(=O)C1=CC=CC=C1NC1=CC(=CC=C1)C(F)(F)F
PTGS2	DB02709	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	experimental; investigational	Resveratrol	OC1=CC=C(\C=C\C2=CC(O)=CC(O)=C2)C=C1
PTGS2	DB03014	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	experimental	Heme	CC1=C(CCC(O)=O)C2=CC3=[N+]4C(=CC5=C(C=C)C(C)=C6C=C7C(C=C)=C(C)C8=[N+]7[Fe@]4(N2C1=C8)N56)C(C)=C3CCC(O)=O
PTGS2	DB03477	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	experimental	1-Phenylsulfonamide-3-Trifluoromethyl-5-Parabromophenylpyrazole	NS(=O)(=O)C1=CC=C(C=C1)N1N=C(C=C1C1=CC=C(Br)C=C1)C(F)(F)F
PTGS2	DB03866	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	experimental	Prostaglandin G2	CCCCC[C@H](OO)\C=C\[C@H]1[C@H]2C[C@H](OO2)[C@@H]1C\C=C/CCCC(O)=O
PTGS2	DB04552	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved	Niflumic Acid	OC(=O)C1=C(NC2=CC=CC(=C2)C(F)(F)F)N=CC=C1
PTGS2	DB04743	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	experimental	Nimesulide	CS(=O)(=O)NC1=CC=C(C=C1OC1=CC=CC=C1)[N+]([O-])=O
PTGS2	DB06725	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved	Lornoxicam	CN1\C(=C(\O)NC2=CC=CC=N2)C(=O)C2=C(C=C(Cl)S2)S1(=O)=O
PTGS2	DB06802	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved	Nepafenac	NC(=O)CC1=CC=CC(C(=O)C2=CC=CC=C2)=C1N
PTGS2	DB00317	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved; investigational	Gefitinib	COC1=C(OCCCN2CCOCC2)C=C2C(NC3=CC(Cl)=C(F)C=C3)=NC=NC2=C1
PTGS2	DB01234	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved; investigational	Dexamethasone	C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
PTGS2	DB00864	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved; investigational	Tacrolimus	CO[C@@H]1C[C@@H](CC[C@H]1O)\C=C(/C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H]([C@H](C[C@H]2C)OC)[C@H](C[C@@H](C)C\C(C)=C\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]1C)OC
PTGS2	DB01242	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved	Clomipramine	CN(C)CCCN1C2=CC=CC=C2CCC2=C1C=C(Cl)C=C2
PTGS2	DB01101	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved; investigational	Capecitabine	CCCCCOC(=O)NC1=NC(=O)N(C=C1F)[C@@H]1O[C@H](C)[C@@H](O)[C@H]1O
PTGS2	DB00526	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	approved; investigational	Oxaliplatin	O=C1O[Pt]2(N[C@@H]3CCCC[C@H]3N2)OC1=O
PYCR1	DB00157	pyrroline-5-carboxylate reductase 1	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
PYCR1	DB00172	pyrroline-5-carboxylate reductase 1	approved; nutraceutical	L-Proline	OC(=O)[C@@H]1CCCN1
PYCR2	DB00157	pyrroline-5-carboxylate reductase family, member 2	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
PYCR2	DB00172	pyrroline-5-carboxylate reductase family, member 2	approved; nutraceutical	L-Proline	OC(=O)[C@@H]1CCCN1
PYGB	DB00114	phosphorylase, glycogen; brain	nutraceutical	Pyridoxal Phosphate	CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O
PYGL	DB00114	phosphorylase, glycogen, liver	nutraceutical	Pyridoxal Phosphate	CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O
PYGL	DB00131	phosphorylase, glycogen, liver	approved; nutraceutical	Adenosine monophosphate	NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
PYGL	DB01696	phosphorylase, glycogen, liver	experimental	7,9-Dihydro-1h-Purine-2,6,8(3h)-Trione	O=C1NC2=C(N1)C(=O)NC(=O)N2
PYGL	DB02089	phosphorylase, glycogen, liver	experimental	CP-526423	ClC1=CC2=C(NC(=C2)C(=O)NCCOCCOCCNC(=O)C2=CC3=C(N2)C=CC(Cl)=C3)C=C1
PYGL	DB02320	phosphorylase, glycogen, liver	experimental	1-N-Acetyl-Beta-D-Glucosamine	CC(=O)N[C@H]1O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]1O
PYGL	DB02379	phosphorylase, glycogen, liver	experimental	Beta-D-Glucose	OC[C@@H]1O[C@H](O)[C@@H](O)[C@H](O)[C@H]1O
PYGL	DB03288	phosphorylase, glycogen, liver	experimental	5-Chloro-1h-Indole-2-Carboxylic Acid{[Cyclopentyl-(2-Hydroxy-Ethyl)-Carbamoyl]-Methyl}-Amide	OCCN([C@H](O)CNC(=O)C1=CC2=CC(Cl)=CC=C2N1)C1CCCC1
PYGL	DB03744	phosphorylase, glycogen, liver	experimental	Cp403700, (S)-1-{2-[(5-Chloro-1h-Indole-2-Carbonyl)-Amino]-3-Phenyl-Propionyl}-Azetidine-3-Carboxylate	OC(=O)C1CN(C1)C(=O)[C@H](CC1=CC=CC=C1)NC(=O)C1=CC2=C(N1)C=CC(Cl)=C2
PYGL	DB04522	phosphorylase, glycogen, liver	experimental	Phosphonoserine	N[C@@H](COP(O)(O)=O)C(O)=O
PYGL	DB07315	phosphorylase, glycogen, liver	experimental	5-chloro-N-{4-[(1R)-1,2-dihydroxyethyl]phenyl}-1H-indole-2-carboxamide	OC[C@H](O)C1=CC=C(NC(=O)C2=CC3=CC(Cl)=CC=C3N2)C=C1
PYGL	DB07395	phosphorylase, glycogen, liver	experimental	4-[3-(2-Chloro-4,5-difluoro-benzoyl)ureido]-3-trifluoromethoxybenzoic acid	OC(=O)C1=CC=C(NC(=O)NC(=O)C2=CC(F)=C(F)C=C2Cl)C(OC(F)(F)F)=C1
PYGL	DB07396	phosphorylase, glycogen, liver	experimental	1-{2-[3-(2-Chloro-4,5-difluoro-benzoyl)-ureido]-4-fluoro-phenyl}-piperidine-4-carboxylic acid	OC(=O)C1CCN(CC1)C1=C(NC(=O)NC(=O)C2=CC(F)=C(F)C=C2Cl)C=C(F)C=C1
PYGL	DB07968	phosphorylase, glycogen, liver	experimental	N-(2-CHLORO-4-FLUOROBENZOYL)-N'-(5-HYDROXY-2-METHOXYPHENYL)UREA	COC1=CC=C(O)C=C1NC(=O)NC(=O)C1=CC=C(F)C=C1Cl
PYGM	DB00114	phosphorylase, glycogen, muscle	nutraceutical	Pyridoxal Phosphate	CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O
PYGM	DB01823	phosphorylase, glycogen, muscle	experimental	Beta-D-Glucopyranose Spirohydantoin	OC[C@H]1O[C@]2(NC(=O)NC2=O)[C@H](O)[C@@H](O)[C@@H]1O
PYGM	DB01843	phosphorylase, glycogen, muscle	experimental	3-Amino-8,9,10-Trihydroxy-7-Hydroxymethyl-6-Oxa-1,3-Diaza-Spiro[4.5]Decane-2,4-Dione	NN1C(=O)N[C@]2(O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)C1=O
PYGM	DB02007	phosphorylase, glycogen, muscle	experimental	Alpha-D-Glucose-6-Phosphate	O[C@H]1O[C@@H](COP(O)(O)=O)[C@H](O)[C@@H](O)[C@@H]1O
PYGM	DB02320	phosphorylase, glycogen, muscle	experimental	1-N-Acetyl-Beta-D-Glucosamine	CC(=O)N[C@H]1O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]1O
PYGM	DB02348	phosphorylase, glycogen, muscle	experimental	Fluoro-Phosphite Ion	[O-]P([O-])(F)=O
PYGM	DB02379	phosphorylase, glycogen, muscle	experimental	Beta-D-Glucose	OC[C@@H]1O[C@H](O)[C@@H](O)[C@H](O)[C@H]1O
PYGM	DB02447	phosphorylase, glycogen, muscle	experimental	3,8,9,10-Tetrahydroxy-7-Hydroxymethyl-6-Oxa-1,3-Diaza-Spiro[4.5]Decane-2,4-Dione	OC[C@H]1O[C@]2(NC(=O)N(O)C2=O)[C@H](O)[C@@H](O)[C@@H]1O
PYGM	DB02471	phosphorylase, glycogen, muscle	experimental	Nojirimycine Tetrazole	OC[C@H]1[C@H](O)[C@@H](O)[C@H](O)C2=NN=NN12
PYGM	DB02519	phosphorylase, glycogen, muscle	experimental	Indirubin-5-Sulphonate	OS(=O)(=O)C1=CC=C2NC(=O)\C(=C3/NC4=CC=CC=C4C3=O)C2=C1
PYGM	DB02604	phosphorylase, glycogen, muscle	experimental	2-Deoxy-Glucose-6-Phosphate	O[C@H]1C[C@@H](O)[C@H](O)[C@@H](COP(O)(O)=O)O1
PYGM	DB02719	phosphorylase, glycogen, muscle	experimental	C-(1-Hydrogyl-Beta-D-Glucopyranosyl) Formamide	NC(=O)[C@]1(O)O[C@@H](CO)[C@H](O)[C@@H](O)[C@H]1O
PYGM	DB02720	phosphorylase, glycogen, muscle	experimental	Alpha-D-Glucopyranosyl-2-Carboxylic Acid Amide	NC(=O)[C@H]1O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]1O
PYGM	DB02843	phosphorylase, glycogen, muscle	experimental	Alpha-D-Glucose-1-Phosphate	OC[C@H]1O[C@H](OP(O)(O)=O)[C@H](O)[C@@H](O)[C@@H]1O
PYGM	DB02964	phosphorylase, glycogen, muscle	experimental	8,9,10-Trihydroxy-7-Hydroxymethyl-2-Thioxo-6-Oxa-1,3-Diaza-Spiro[4.5]Decan-4-One	OC[C@H]1O[C@]2(NC(=S)NC2=O)[C@H](O)[C@@H](O)[C@@H]1O
PYGM	DB03067	phosphorylase, glycogen, muscle	experimental	4-{2,4-Bis[(3-Nitrobenzoyl)Amino]Phenoxy}Phthalic Acid	OC(=O)C1=C(C=C(OC2=C(NC(=O)C3=CC(=CC=C3)[N+]([O-])=O)C=C(NC(=O)C3=CC(=CC=C3)[N+]([O-])=O)C=C2)C=C1)C(O)=O
PYGM	DB03133	phosphorylase, glycogen, muscle	experimental	2-(Beta-D-Glucopyranosyl)-5-Methyl-1,2,3-Benzimidazole	Cc1ccc2nc(nc2c1)[C@H]1O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]1O
PYGM	DB03218	phosphorylase, glycogen, muscle	experimental	N-Acetyl-N'-Beta-D-Glucopyranosyl Urea	CC(=O)NC(=O)N[C@H]1O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]1O
PYGM	DB03250	phosphorylase, glycogen, muscle	experimental	2-(Beta-D-Glucopyranosyl)-5-Methyl-1,3,4-Benzothiazole	CC1=CC=C2SC(=NC2=C1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O
PYGM	DB03286	phosphorylase, glycogen, muscle	experimental	C-(1-Azido-Alpha-D-Glucopyranosyl) Formamide	N[C@@H](O)[C@@]1(O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]1O)N=[N+]=[N-]
PYGM	DB03354	phosphorylase, glycogen, muscle	experimental	2-(Beta-D-Glucopyranosyl)-5-Methyl-1,3,4-Oxadiazole	CC1=NN=C(O1)[C@H]1O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]1O
PYGM	DB03383	phosphorylase, glycogen, muscle	experimental	5-Chloro-1h-Indole-2-Carboxylic Acid [1-(4-Fluorobenzyl)-2-(4-Hydroxypiperidin-1yl)-2-Oxoethyl]Amide	OC1CCN(CC1)C(=O)[C@H](CC1=CC=C(F)C=C1)NC(=O)C1=CC2=C(N1)C=CC(Cl)=C2
PYGM	DB03392	phosphorylase, glycogen, muscle	experimental	(3,4,5-Trihydroxy-6-Hydroxymethyl-Tetrahydro-Pyran-2-Yl)-Phosphoramidic Acid Dimethyl Ester	COP(=O)(N[C@H]1O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]1O)OC
PYGM	DB03479	phosphorylase, glycogen, muscle	experimental	8,9,10-Trihydroxy-7-Hydroxymethyl-3-Methyl-6-Oxa-1,3-Diaza-Spiro[4.5]Decane-2,4-Dione	CN1C(=O)N[C@]2(O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)C1=O
PYGM	DB03496	phosphorylase, glycogen, muscle	experimental; investigational	Flavopiridol	CN1CC[C@@H]([C@H](O)C1)C1=C(O)C=C(O)C2=C1OC(=CC2=O)C1=CC=CC=C1Cl
PYGM	DB03657	phosphorylase, glycogen, muscle	experimental	1-Deoxy-1-Methoxycarbamido-Beta-D-Glucopyranose	COC(=O)N[C@H]1O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]1O
PYGM	DB03835	phosphorylase, glycogen, muscle	experimental	N-(8,9,10-Trihydroxy-7-Hydroxymethyl-2,4-Dioxo-6-Oxa-1,3-Diaza-Spiro[4.5]Dec-3-Yl-Acetamide	CC(=O)NN1C(=O)N[C@]2(O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)C1=O
PYGM	DB04013	phosphorylase, glycogen, muscle	experimental	1-Deoxy-1-Methoxycarbamido-Beta-D-Gluco-2-Heptulopyranosonamide	COC(=O)N[C@]1(O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]1O)C(N)=O
PYGM	DB04044	phosphorylase, glycogen, muscle	experimental	4-{2-[(3-Nitrobenzoyl)Amino]Phenoxy}Phthalic Acid	OC(=O)C1=C(C=C(OC2=C(NC(=O)C3=CC(=CC=C3)[N+]([O-])=O)C=CC=C2)C=C1)C(O)=O
PYGM	DB04055	phosphorylase, glycogen, muscle	experimental	2,3-Dicarboxy-4-(2-Chloro-Phenyl)-1-Ethyl-5-Isopropoxycarbonyl-6-Methyl-Pyridinium	CC[N+]1=C(C)C(C(=O)OC(C)C)=C(C2=CC=CC=C2Cl)C(C(O)=O)=C1C(O)=O
PYGM	DB04083	phosphorylase, glycogen, muscle	experimental	N'-Pyridoxyl-Lysine-5'-Monophosphate	CC1=NC=C(COP(O)(O)=O)C(CNCCCC[C@@H](N)C(O)=O)=C1O
PYGM	DB04195	phosphorylase, glycogen, muscle	experimental	Heptulose-2-Phosphate	C[C@]1(OP(O)(O)=O)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O
PYGM	DB04295	phosphorylase, glycogen, muscle	experimental	N-Benzoyl-N'-Beta-D-Glucopyranosyl Urea	OC[C@@H]1O[C@H](NC(=O)NC(=O)C2=CC=CC=C2)[C@@H](O)[C@H](O)[C@H]1O
PYGM	DB04522	phosphorylase, glycogen, muscle	experimental	Phosphonoserine	N[C@@H](COP(O)(O)=O)C(O)=O
PYGM	DB04544	phosphorylase, glycogen, muscle	experimental	1-Deoxy-1-Acetylamino-Beta-D-Gluco-2-Heptulopyranosonamide	CC(=O)N[C@@]1(O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]1O)C(N)=O
PYGM	DB04566	phosphorylase, glycogen, muscle	experimental	Inosinic Acid	O[C@H]1[C@H](COP(O)(O)=O)O[C@H]([C@@H]1O)N1C=NC2=C1N=CNC2=O
PYGM	DB04642	phosphorylase, glycogen, muscle	experimental	7-{2,6-DICHLORO-4-[3-(2-CHLORO-BENZOYL)-UREIDO]-PHENOXY}-HEPTANOIC ACID	OC(=O)CCCCCCOC1=C(Cl)C=C(NC(=O)NC(=O)C2=CC=CC=C2Cl)C=C1Cl
PYGM	DB04643	phosphorylase, glycogen, muscle	experimental	4-{3-CHLORO-4-[3-(2,4-DICHLORO-BENZOYL)-UREIDO]-PHENOXY}-BUTYRIC ACID	OC(=O)CCCOC1=CC=C(NC(=O)NC(=O)C2=CC=C(Cl)C=C2Cl)C(Cl)=C1
PYGM	DB04644	phosphorylase, glycogen, muscle	experimental	4-{4-[3-(2,4-DICHLORO-BENZOYL)-UREIDO]-2,3-DIMETHYL-PHENOXY}-BUTYRIC ACID	CC1=C(C)C(OCCCC(O)=O)=CC=C1NC(=O)NC(=O)C1=CC=C(Cl)C=C1Cl
PYGM	DB04645	phosphorylase, glycogen, muscle	experimental	5-{3-[3-(2,4-DICHLORO-BENZOYL)-UREIDO]-2-METHYL-PHENOXY}-PENTANOIC ACID	CC1=C(NC(=O)NC(=O)C2=CC=C(Cl)C=C2Cl)C=CC=C1OCCCCC(O)=O
PYGM	DB06986	phosphorylase, glycogen, muscle	experimental	2-CHLORO-N-[(1R,2R)-1-HYDROXY-2,3-DIHYDRO-1H-INDEN-2-YL]-6H-THIENO[2,3-B]PYRROLE-5-CARBOXAMIDE	O[C@H]1[C@@H](CC2=C1C=CC=C2)NC(=O)C1=CC2=C(N1)SC(Cl)=C2
PYGM	DB07066	phosphorylase, glycogen, muscle	experimental	2-CHLORO-N-[(3R)-2-OXO-1,2,3,4-TETRAHYDROQUINOLIN-3-YL]-6H-THIENO[2,3-B]PYRROLE-5-CARBOXAMIDE	ClC1=CC2=C(NC(=C2)C(=O)N[C@@H]2CC3=C(NC2=O)C=CC=C3)S1
PYGM	DB07792	phosphorylase, glycogen, muscle	experimental	(S)-2-CHLORO-N-(1-(2-(2-HYDROXYETHYLAMINO)-2-OXOETHYL)-2-OXO-1,2,3,4-TETRAHYDROQUINOLIN-3-YL)-6H-THIENO[2,3-B]PYRROLE-5-CARBOXAMIDE	OCCNC(=O)CN1C(=O)[C@H](CC2=C1C=CC=C2)NC(=O)C1=CC2=C(N1)SC(Cl)=C2
PYGM	DB07793	phosphorylase, glycogen, muscle	experimental	(2S)-N-[(3S)-1-(2-AMINO-2-OXOETHYL)-2-OXO-1,2,3,4-TETRAHYDROQUINOLIN-3-YL]-2-CHLORO-2H-THIENO[2,3-B]PYRROLE-5-CARBOXAMIDE	NC(=O)CN1C(=O)[C@H](CC2=C1C=CC=C2)NC(=O)C1=CC2=C[C@H](Cl)SC2=N1
PYGM	DB07807	phosphorylase, glycogen, muscle	experimental	(3R,4R,5R)-5-(HYDROXYMETHYL)-1-(3-PHENYLPROPYL)PIPERIDINE-3,4-DIOL	OC[C@H]1CN(CCCC2=CC=CC=C2)C[C@@H](O)[C@@H]1O
PYGM	DB07949	phosphorylase, glycogen, muscle	experimental	({[(3E)-2'-OXO-2',7'-DIHYDRO-2,3'-BIINDOL-3(7H)-YLIDENE]AMINO}OXY)ACETIC ACID	OC(=O)CO\N=C1/C2=CC=CCC2=N/C/1=C1\C(=O)N=C2CC=CC=C12
PYGM	DB08151	phosphorylase, glycogen, muscle	experimental	(5R,7R,8S,9S,10R)-7-(hydroxymethyl)-3-phenyl-1,6-dioxa-2-azaspiro[4.5]dec-2-ene-8,9,10-triol	OC[C@H]1O[C@@]2(CC(=NO2)C2=CC=CC=C2)[C@H](O)[C@@H](O)[C@@H]1O
PYGM	DB08322	phosphorylase, glycogen, muscle	experimental	2-DEOXY-3,4-BIS-O-[3-(4-HYDROXYPHENYL)PROPANOYL]-L-THREO-PENTARIC ACID	OC(=O)C[C@H](OC(=O)\C=C\C1=CC=C(O)C=C1)[C@@H](OC(=O)\C=C\C1=CC=C(O)C=C1)C(O)=O
PYGM	DB08500	phosphorylase, glycogen, muscle	experimental	(3S,5R,7R,8S,9S,10R)-7-(hydroxymethyl)-3-(2-naphthyl)-1,6-dioxa-2-azaspiro[4.5]decane-8,9,10-triol	OC[C@H]1O[C@@]2(C[C@H](NO2)C2=CC3=CC=CC=C3C=C2)[C@H](O)[C@@H](O)[C@@H]1O
PYGM	DB08503	phosphorylase, glycogen, muscle	experimental	(3S,5R,7R,8S,9S,10R)-7-(hydroxymethyl)-3-(4-methylphenyl)-1,6-dioxa-2-azaspiro[4.5]decane-8,9,10-triol	CC1=CC=C(C=C1)[C@@H]1C[C@]2(ON1)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O
PYGM	DB01076	phosphorylase, glycogen, muscle	approved	Atorvastatin	CC(C)C1=C(C(=O)NC2=CC=CC=C2)C(=C(N1CC[C@@H](O)C[C@@H](O)CC(O)=O)C1=CC=C(F)C=C1)C1=CC=CC=C1
PYGM	DB00439	phosphorylase, glycogen, muscle	withdrawn	Cerivastatin	COCC1=C(C2=CC=C(F)C=C2)C(\C=C\[C@@H](O)C[C@@H](O)CC(O)=O)=C(C(C)C)N=C1C(C)C
PYGM	DB01095	phosphorylase, glycogen, muscle	approved	Fluvastatin	CC(C)N1C(\C=C\[C@H](O)C[C@H](O)CC(O)=O)=C(C2=CC=C(F)C=C2)C2=CC=CC=C12
PYGM	DB00175	phosphorylase, glycogen, muscle	approved	Pravastatin	CC[C@H](C)C(=O)O[C@H]1C[C@H](O)C=C2C=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC(O)=O)[C@@H]12
PYGM	DB01098	phosphorylase, glycogen, muscle	approved	Rosuvastatin	CC(C)C1=NC(=NC(C2=CC=C(F)C=C2)=C1\C=C\[C@H](O)C[C@@H](O)CC(O)=O)N(C)S(=O)(=O)C
PYGM	DB00641	phosphorylase, glycogen, muscle	approved	Simvastatin	CCC(C)(C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CCC3C[C@@H](O)CC(=O)O3)[C@@H]12
QDPR	DB00157	quinoid dihydropteridine reductase	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
QDPR	DB01907	quinoid dihydropteridine reductase	experimental	Nicotinamide-Adenine-Dinucleotide	NC(=O)C1=CC=C[N+](=C1)[C@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@@H]1O
QDPR	DB03814	quinoid dihydropteridine reductase	experimental	2-(N-Morpholino)-Ethanesulfonic Acid	[O-]S(=O)(=O)CC[NH+]1CCOCC1
QDPR	DB00143	quinoid dihydropteridine reductase	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
QDPR	DB00120	quinoid dihydropteridine reductase	approved; nutraceutical	L-Phenylalanine	N[C@@H](CC1=CC=CC=C1)C(O)=O
QDPR	DB00135	quinoid dihydropteridine reductase	approved; nutraceutical	L-Tyrosine	N[C@@H](CC1=CC=C(O)C=C1)C(O)=O
QDPR	DB00360	quinoid dihydropteridine reductase	approved; investigational	Tetrahydrobiopterin	CC(O)C(O)C1CNC2=C(N1)C(=O)N=C(N)N2
QPRT	DB00627	quinolinate phosphoribosyltransferase	approved; nutraceutical; investigational	Niacin	OC(=O)C1=CN=CC=C1
QPRT	DB01796	quinolinate phosphoribosyltransferase	experimental	Quinolinic Acid	OC(=O)C1=CC=CN=C1C(O)=O
QPRT	DB02382	quinolinate phosphoribosyltransferase	experimental	Namn	O[C@@H]1[C@@H](O)[C@@H](O[C@H]1CO[P@@](O)([O-])=O)[N+]1=CC=CC(=C1)C(O)=O
QPRT	DB02746	quinolinate phosphoribosyltransferase	experimental	Phthalic Acid	OC(=O)C1=CC=CC=C1C(O)=O
QPRT	DB04294	quinolinate phosphoribosyltransferase	experimental	5-Phosphoribosyl-1-(Beta-Methylene) Pyrophosphate	O[C@@H]1[C@@H](O)[C@H](O[P@](O)(=O)CP(O)(O)=O)O[C@H]1COP(O)(O)=O
QPRT	DB00160	quinolinate phosphoribosyltransferase	approved; nutraceutical	L-Alanine	C[C@H](N)C(O)=O
QPRT	DB00130	quinolinate phosphoribosyltransferase	approved; nutraceutical; investigational	L-Glutamine	N[C@@H](CCC(N)=O)C(O)=O
QPRT	DB00150	quinolinate phosphoribosyltransferase	approved; nutraceutical	L-Tryptophan	N[C@@H](CC1=CNC2=CC=CC=C12)C(O)=O
RAPGEF3	DB00171	Rap guanine nucleotide exchange factor (GEF) 3	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
RAPGEF3	DB00770	Rap guanine nucleotide exchange factor (GEF) 3	approved; investigational	Alprostadil	CCCCC[C@H](O)C=C[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(O)=O
RAPGEF3	DB00668	Rap guanine nucleotide exchange factor (GEF) 3	approved	Epinephrine	CNC[C@H](O)C1=CC(O)=C(O)C=C1
RAPGEF4	DB01124	Rap guanine nucleotide exchange factor (GEF) 4	approved	Tolbutamide	CCCCNC(=O)NS(=O)(=O)C1=CC=C(C)C=C1
RDH11	DB00162	retinol dehydrogenase 11 (all-trans/9-cis/11-cis)	approved; nutraceutical	Vitamin A	CC(=CCO)C=CC=C(C)C=CC1=C(C)CCCC1(C)C
RDH12	DB00162	retinol dehydrogenase 12 (all-trans/9-cis/11-cis)	approved; nutraceutical	Vitamin A	CC(=CCO)C=CC=C(C)C=CC1=C(C)CCCC1(C)C
RDH5	DB00157	retinol dehydrogenase 5 (11-cis/9-cis)	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
RDH5	DB00162	retinol dehydrogenase 5 (11-cis/9-cis)	approved; nutraceutical	Vitamin A	CC(=CCO)C=CC=C(C)C=CC1=C(C)CCCC1(C)C
RDH8	DB00162	retinol dehydrogenase 8 (all-trans)	approved; nutraceutical	Vitamin A	CC(=CCO)C=CC=C(C)C=CC1=C(C)CCCC1(C)C
RENBP	DB00141	renin binding protein	approved; nutraceutical	N-Acetyl-D-glucosamine	CC(=O)N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O
RETSAT	DB00162	retinol saturase (all-trans-retinol 13,14-reductase)	approved; nutraceutical	Vitamin A	CC(=CCO)C=CC=C(C)C=CC1=C(C)CCCC1(C)C
RFK	DB00140	riboflavin kinase	approved; nutraceutical	Riboflavin	CC1=C(C)C=C2N(C[C@H](O)[C@H](O)[C@H](O)CO)C3=NC(=O)NC(=O)C3=NC2=C1
RFK	DB03247	riboflavin kinase	experimental	Riboflavin Monophosphate	CC1=CC2=C(C=C1C)N(C[C@@H](O)[C@@H](O)[C@H](O)COP(O)(O)=O)C1=NC(=O)NC(=O)C1=N2
RFK	DB03431	riboflavin kinase	experimental	Adenosine-5'-Diphosphate	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](CO[P@](O)(=O)OP(O)(O)=O)[C@H](O)[C@H]1O
RORA	DB00709	RAR-related orphan receptor A	approved; investigational	Lamivudine	NC1=NC(=O)N(C=C1)[C@@H]1CS[C@H](CO)O1
RPIA	DB02053	ribose 5-phosphate isomerase A	experimental	Ribose-5-Phosphate	OC[C@@H](O)[C@H](O)[C@@H](O)COP(O)(O)=O
RPIA	DB03745	ribose 5-phosphate isomerase A	experimental	Arabinose-5-Phosphate	OC[C@@H](O)[C@H](O)[C@@H](O)COP(O)(O)=O
RPIA	DB04127	ribose 5-phosphate isomerase A	experimental	Beta-D-Arabinofuranose-5'-Phosphate	O[C@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@@H]1O
RPIA	DB04272	ribose 5-phosphate isomerase A	experimental	Citric Acid	OC(=O)CC(O)(CC(O)=O)C(O)=O
RPL11	DB02494	ribosomal protein L11	experimental	Alpha-Hydroxy-Beta-Phenyl-Propionic Acid	O[C@@H](CC1=CC=CC=C1)C(O)=O
RPL11	DB07374	ribosomal protein L11	experimental	ANISOMYCIN	COC1=CC=C(C[C@H]2NC[C@H](O)[C@H]2OC(C)=O)C=C1
RPL11	DB08437	ribosomal protein L11	experimental	PUROMYCIN	COC1=CC=C(C[C@H](N)C(=O)N[C@@H]2[C@@H](CO)O[C@H]([C@@H]2O)N2C=NC3=C(N=CN=C23)N(C)C)C=C1
RPL13	DB01248	ribosomal protein L13	approved; investigational	Docetaxel	CC(=O)O[C@@]12CO[C@@H]1C[C@H](O)[C@]1(C)[C@@H]2[C@H](OC(=O)C2=CC=CC=C2)[C@]2(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C3=CC=CC=C3)C(C)=C([C@@H](O)C1=O)C2(C)C
RPL13	DB01041	ribosomal protein L13	approved; withdrawn; investigational	Thalidomide	O=C1N(C2CCC(=O)NC2=O)C(=O)C2=CC=CC=C12
RPL13A	DB02494	ribosomal protein L13a	experimental	Alpha-Hydroxy-Beta-Phenyl-Propionic Acid	O[C@@H](CC1=CC=CC=C1)C(O)=O
RPL13A	DB07374	ribosomal protein L13a	experimental	ANISOMYCIN	COC1=CC=C(C[C@H]2NC[C@H](O)[C@H]2OC(C)=O)C=C1
RPL13A	DB08437	ribosomal protein L13a	experimental	PUROMYCIN	COC1=CC=C(C[C@H](N)C(=O)N[C@@H]2[C@@H](CO)O[C@H]([C@@H]2O)N2C=NC3=C(N=CN=C23)N(C)C)C=C1
RPL15	DB02494	ribosomal protein L15	experimental	Alpha-Hydroxy-Beta-Phenyl-Propionic Acid	O[C@@H](CC1=CC=CC=C1)C(O)=O
RPL15	DB07374	ribosomal protein L15	experimental	ANISOMYCIN	COC1=CC=C(C[C@H]2NC[C@H](O)[C@H]2OC(C)=O)C=C1
RPL15	DB08437	ribosomal protein L15	experimental	PUROMYCIN	COC1=CC=C(C[C@H](N)C(=O)N[C@@H]2[C@@H](CO)O[C@H]([C@@H]2O)N2C=NC3=C(N=CN=C23)N(C)C)C=C1
RPL19	DB02494	ribosomal protein L19	experimental	Alpha-Hydroxy-Beta-Phenyl-Propionic Acid	O[C@@H](CC1=CC=CC=C1)C(O)=O
RPL19	DB07374	ribosomal protein L19	experimental	ANISOMYCIN	COC1=CC=C(C[C@H]2NC[C@H](O)[C@H]2OC(C)=O)C=C1
RPL19	DB08437	ribosomal protein L19	experimental	PUROMYCIN	COC1=CC=C(C[C@H](N)C(=O)N[C@@H]2[C@@H](CO)O[C@H]([C@@H]2O)N2C=NC3=C(N=CN=C23)N(C)C)C=C1
RPL23	DB02494	ribosomal protein L23	experimental	Alpha-Hydroxy-Beta-Phenyl-Propionic Acid	O[C@@H](CC1=CC=CC=C1)C(O)=O
RPL23	DB07374	ribosomal protein L23	experimental	ANISOMYCIN	COC1=CC=C(C[C@H]2NC[C@H](O)[C@H]2OC(C)=O)C=C1
RPL23	DB08437	ribosomal protein L23	experimental	PUROMYCIN	COC1=CC=C(C[C@H](N)C(=O)N[C@@H]2[C@@H](CO)O[C@H]([C@@H]2O)N2C=NC3=C(N=CN=C23)N(C)C)C=C1
RPL23A	DB02494	ribosomal protein L23a	experimental	Alpha-Hydroxy-Beta-Phenyl-Propionic Acid	O[C@@H](CC1=CC=CC=C1)C(O)=O
RPL23A	DB07374	ribosomal protein L23a	experimental	ANISOMYCIN	COC1=CC=C(C[C@H]2NC[C@H](O)[C@H]2OC(C)=O)C=C1
RPL23A	DB08437	ribosomal protein L23a	experimental	PUROMYCIN	COC1=CC=C(C[C@H](N)C(=O)N[C@@H]2[C@@H](CO)O[C@H]([C@@H]2O)N2C=NC3=C(N=CN=C23)N(C)C)C=C1
RPL26L1	DB02494	ribosomal protein L26-like 1	experimental	Alpha-Hydroxy-Beta-Phenyl-Propionic Acid	O[C@@H](CC1=CC=CC=C1)C(O)=O
RPL26L1	DB07374	ribosomal protein L26-like 1	experimental	ANISOMYCIN	COC1=CC=C(C[C@H]2NC[C@H](O)[C@H]2OC(C)=O)C=C1
RPL26L1	DB08437	ribosomal protein L26-like 1	experimental	PUROMYCIN	COC1=CC=C(C[C@H](N)C(=O)N[C@@H]2[C@@H](CO)O[C@H]([C@@H]2O)N2C=NC3=C(N=CN=C23)N(C)C)C=C1
RPL3	DB02494	ribosomal protein L3	experimental	Alpha-Hydroxy-Beta-Phenyl-Propionic Acid	O[C@@H](CC1=CC=CC=C1)C(O)=O
RPL3	DB07374	ribosomal protein L3	experimental	ANISOMYCIN	COC1=CC=C(C[C@H]2NC[C@H](O)[C@H]2OC(C)=O)C=C1
RPL3	DB08437	ribosomal protein L3	experimental	PUROMYCIN	COC1=CC=C(C[C@H](N)C(=O)N[C@@H]2[C@@H](CO)O[C@H]([C@@H]2O)N2C=NC3=C(N=CN=C23)N(C)C)C=C1
RPL37	DB02494	ribosomal protein L37	experimental	Alpha-Hydroxy-Beta-Phenyl-Propionic Acid	O[C@@H](CC1=CC=CC=C1)C(O)=O
RPL37	DB04602	ribosomal protein L37	experimental	PUROMYCIN AMINONUCLEOSIDE-5'-MONOPHOSPHATE	CN(C)C1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](N)[C@H]1O
RPL37	DB04805	ribosomal protein L37	experimental	Virginiamycin factor S1	CC[C@@H]1NC(=O)[C@@H](NC(=O)C2=C(O)C=CC=N2)[C@@H](C)OC(=O)[C@@H](NC(=O)[C@@H]2CC(=O)CCN2C(=O)[C@@H](CC2=CC=CC=C2)N(C)C(=O)[C@H]2CCCN2C1=O)C1=CC=CC=C1
RPL37	DB07374	ribosomal protein L37	experimental	ANISOMYCIN	COC1=CC=C(C[C@H]2NC[C@H](O)[C@H]2OC(C)=O)C=C1
RPL37	DB08437	ribosomal protein L37	experimental	PUROMYCIN	COC1=CC=C(C[C@H](N)C(=O)N[C@@H]2[C@@H](CO)O[C@H]([C@@H]2O)N2C=NC3=C(N=CN=C23)N(C)C)C=C1
RPL5	DB03721	ribosomal protein L5	experimental	O-Sialic Acid	CC(=O)N[C@H]1[C@H](O)C[C@](O)(O[C@@H]1[C@@H](O)[C@@H](O)CO)C(O)=O
RPL5	DB01033	ribosomal protein L5	approved	Mercaptopurine	S=C1N=CNC2=C1NC=N2
RPL5	DB00563	ribosomal protein L5	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
RPL8	DB02494	ribosomal protein L8	experimental	Alpha-Hydroxy-Beta-Phenyl-Propionic Acid	O[C@@H](CC1=CC=CC=C1)C(O)=O
RPL8	DB07374	ribosomal protein L8	experimental	ANISOMYCIN	COC1=CC=C(C[C@H]2NC[C@H](O)[C@H]2OC(C)=O)C=C1
RPL8	DB08437	ribosomal protein L8	experimental	PUROMYCIN	COC1=CC=C(C[C@H](N)C(=O)N[C@@H]2[C@@H](CO)O[C@H]([C@@H]2O)N2C=NC3=C(N=CN=C23)N(C)C)C=C1
RPLP2	DB02212	ribosomal protein, large, P2	experimental	Pyrophosphate 2-	O[P@]([O-])(=O)O[P@@](O)([O-])=O
RPLP2	DB04137	ribosomal protein, large, P2	experimental	Guanosine-5'-Triphosphate	NC1=NC2=C(N=CN2[C@@H]2O[C@@H](CO[P@](O)(=O)O[P@@](O)(=O)OP(O)(O)=O)[C@H](O)[C@H]2O)C(=O)N1
RPN1	DB00171	ribophorin I	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
RPN2	DB01248	ribophorin II	approved; investigational	Docetaxel	CC(=O)O[C@@]12CO[C@@H]1C[C@H](O)[C@]1(C)[C@@H]2[C@H](OC(=O)C2=CC=CC=C2)[C@]2(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C3=CC=CC=C3)C(C)=C([C@@H](O)C1=O)C2(C)C
RPN2	DB00171	ribophorin II	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
RPS6	DB00877	ribosomal protein S6	approved; investigational	Sirolimus	CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1O
RRM1	DB00242	ribonucleotide reductase M1	approved; investigational	Cladribine	NC1=C2N=CN([C@H]3C[C@H](O)[C@@H](CO)O3)C2=NC(Cl)=N1
RRM1	DB00441	ribonucleotide reductase M1	approved	Gemcitabine	NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](CO)[C@@H](O)C1(F)F
RRM1	DB00631	ribonucleotide reductase M1	approved; investigational	Clofarabine	NC1=C2N=CN([C@@H]3O[C@H](CO)[C@@H](O)[C@@H]3F)C2=NC(Cl)=N1
RRM1	DB01005	ribonucleotide reductase M1	approved	Hydroxyurea	NC(=O)NO
RRM1	DB01073	ribonucleotide reductase M1	approved	Fludarabine	NC1=C2N=CN([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@@H]3O)C2=NC(F)=N1
RRM1	DB00987	ribonucleotide reductase M1	approved; investigational	Cytarabine	NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O
RRM1	DB01101	ribonucleotide reductase M1	approved; investigational	Capecitabine	CCCCCOC(=O)NC1=NC(=O)N(C=C1F)[C@@H]1O[C@H](C)[C@@H](O)[C@H]1O
RRM1	DB00544	ribonucleotide reductase M1	approved	Fluorouracil	FC1=CNC(=O)NC1=O
RRM1	DB00130	ribonucleotide reductase M1	approved; nutraceutical; investigational	L-Glutamine	N[C@@H](CCC(N)=O)C(O)=O
RRM1	DB00515	ribonucleotide reductase M1	approved	Cisplatin	N[Pt](N)(Cl)Cl
RRM2	DB00242	ribonucleotide reductase M2	approved; investigational	Cladribine	NC1=C2N=CN([C@H]3C[C@H](O)[C@@H](CO)O3)C2=NC(Cl)=N1
RRM2	DB05260	ribonucleotide reductase M2	approved; investigational	Gallium nitrate	[Ga+3].[O-][N+]([O-])=O.[O-][N+]([O-])=O.[O-][N+]([O-])=O
RRM2	DB00987	ribonucleotide reductase M2	approved; investigational	Cytarabine	NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O
RRM2	DB01101	ribonucleotide reductase M2	approved; investigational	Capecitabine	CCCCCOC(=O)NC1=NC(=O)N(C=C1F)[C@@H]1O[C@H](C)[C@@H](O)[C@H]1O
RRM2	DB00544	ribonucleotide reductase M2	approved	Fluorouracil	FC1=CNC(=O)NC1=O
RRM2	DB00130	ribonucleotide reductase M2	approved; nutraceutical; investigational	L-Glutamine	N[C@@H](CCC(N)=O)C(O)=O
RRM2	DB00441	ribonucleotide reductase M2	approved	Gemcitabine	NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](CO)[C@@H](O)C1(F)F
RRM2	DB00515	ribonucleotide reductase M2	approved	Cisplatin	N[Pt](N)(Cl)Cl
RRM2	DB01050	ribonucleotide reductase M2	approved	Ibuprofen	CC(C)CC1=CC=C(C=C1)C(C)C(O)=O
RRM2B	DB00242	ribonucleotide reductase M2 B (TP53 inducible)	approved; investigational	Cladribine	NC1=C2N=CN([C@H]3C[C@H](O)[C@@H](CO)O3)C2=NC(Cl)=N1
RXRA	DB00210	retinoid X receptor, alpha	approved	Adapalene	COC1=C(C=C(C=C1)C1=CC2=C(C=C1)C=C(C=C2)C(O)=O)C12CC3CC(CC(C3)C1)C2
RXRA	DB00307	retinoid X receptor, alpha	approved; investigational	Bexarotene	CC1=CC2=C(C=C1C(=C)C1=CC=C(C=C1)C(O)=O)C(C)(C)CCC2(C)C
RXRA	DB00459	retinoid X receptor, alpha	approved	Acitretin	COC1=C(C)C(C)=C(\C=C\C(\C)=C\C=C\C(\C)=C/C(O)=O)C(C)=C1
RXRA	DB00523	retinoid X receptor, alpha	approved; investigational	Alitretinoin	C\C(\C=C\C1=C(C)CCCC1(C)C)=C\C=C\C(\C)=C\C(O)=O
RXRA	DB00749	retinoid X receptor, alpha	approved; investigational	Etodolac	CCC1=C2NC3=C(CCOC3(CC)CC(O)=O)C2=CC=C1
RXRA	DB00926	retinoid X receptor, alpha	withdrawn	Etretinate	CCOC(=O)C=C(C)C=CC=C(C)C=CC1=C(C)C(C)=C(OC)C=C1C
RXRA	DB07557	retinoid X receptor, alpha	experimental	(5BETA)-PREGNANE-3,20-DIONE	CC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C
RXRA	DB07863	retinoid X receptor, alpha	experimental	2-chloro-5-nitro-N-phenylbenzamide	[O-][N+](=O)C1=CC=C(Cl)C(=C1)C(=O)NC1=CC=CC=C1
RXRA	DB08063	retinoid X receptor, alpha	experimental	1-BENZYL-3-(4-METHOXYPHENYLAMINO)-4-PHENYLPYRROLE-2,5-DIONE	COC1=CC=C(NC2=C(C(=O)N(CC3=CC=CC=C3)C2=O)C2=CC=CC=C2)C=C1
RXRA	DB08402	retinoid X receptor, alpha	experimental	2-[(2,4-DICHLOROBENZOYL)AMINO]-5-(PYRIMIDIN-2-YLOXY)BENZOIC ACID	OC(=O)C1=C(NC(=O)C2=C(Cl)C=C(Cl)C=C2)C=CC(OC2=NC=CC=N2)=C1
RXRA	DB08601	retinoid X receptor, alpha	experimental	tributylstannanyl	CCCC[Sn](CCCC)CCCC
RXRA	DB00755	retinoid X receptor, alpha	approved; nutraceutical; investigational	Tretinoin	CC(C=CC1=C(C)CCCC1(C)C)=CC=CC(C)=CC(O)=O
RXRA	DB00741	retinoid X receptor, alpha	approved	Hydrocortisone	C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
RXRA	DB01132	retinoid X receptor, alpha	approved; investigational	Pioglitazone	CCC1=CN=C(CCOC2=CC=C(CC3SC(=O)NC3=O)C=C2)C=C1
RXRA	DB00412	retinoid X receptor, alpha	approved; investigational	Rosiglitazone	CN(CCOC1=CC=C(CC2SC(=O)NC2=O)C=C1)C1=CC=CC=N1
RXRA	DB00197	retinoid X receptor, alpha	withdrawn	Troglitazone	CC1=C(C)C2=C(CCC(C)(COC3=CC=C(CC4SC(=O)NC4=O)C=C3)O2)C(C)=C1O
SCARB1	DB00144	scavenger receptor class B, member 1	approved; nutraceutical	Phosphatidylserine	CCCC(=O)O[C@H](COC(=O)CC)COP(O)(=O)OC[C@H](N)C(O)=O
SCARB1	DB01039	scavenger receptor class B, member 1	approved	Fenofibrate	CC(C)OC(=O)C(C)(C)OC1=CC=C(C=C1)C(=O)C1=CC=C(Cl)C=C1
SCARB1	DB00334	scavenger receptor class B, member 1	approved; investigational	Olanzapine	CN1CCN(CC1)C1=C2C=C(C)SC2=NC2=CC=CC=C2N1
SCP2	DB00145	sterol carrier protein 2	approved; nutraceutical	Glycine	NCC(O)=O
SDC2	DB00860	syndecan 2	approved	Prednisolone	C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
SDC3	DB00987	syndecan 3	approved; investigational	Cytarabine	NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O
SDHA	DB00139	succinate dehydrogenase complex, subunit A, flavoprotein (Fp)	approved; nutraceutical	Succinic acid	OC(=O)CCC(O)=O
SDHA	DB04141	succinate dehydrogenase complex, subunit A, flavoprotein (Fp)	experimental	2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol	CCCCCCO[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O
SDHA	DB04657	succinate dehydrogenase complex, subunit A, flavoprotein (Fp)	experimental	Carboxin	CC1=C(SCCO1)C(=O)NC1=CC=CC=C1
SDHA	DB04795	succinate dehydrogenase complex, subunit A, flavoprotein (Fp)	experimental	Thenoyltrifluoroacetone	FC(F)(F)C(=O)CC(=O)C1=CC=CS1
SDHA	DB08689	succinate dehydrogenase complex, subunit A, flavoprotein (Fp)	experimental	UBIQUINONE-1	COC1=C(OC)C(=O)C(CC=C(C)C)=C(C)C1=O
SDHB	DB00139	succinate dehydrogenase complex, subunit B, iron sulfur (Ip)	approved; nutraceutical	Succinic acid	OC(=O)CCC(O)=O
SDHB	DB04141	succinate dehydrogenase complex, subunit B, iron sulfur (Ip)	experimental	2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol	CCCCCCO[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O
SDHB	DB08689	succinate dehydrogenase complex, subunit B, iron sulfur (Ip)	experimental	UBIQUINONE-1	COC1=C(OC)C(=O)C(CC=C(C)C)=C(C)C1=O
SDHC	DB00139	succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa	approved; nutraceutical	Succinic acid	OC(=O)CCC(O)=O
SDHC	DB04141	succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa	experimental	2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol	CCCCCCO[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O
SDHC	DB08689	succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa	experimental	UBIQUINONE-1	COC1=C(OC)C(=O)C(CC=C(C)C)=C(C)C1=O
SDHD	DB00139	succinate dehydrogenase complex, subunit D, integral membrane protein	approved; nutraceutical	Succinic acid	OC(=O)CCC(O)=O
SDHD	DB00756	succinate dehydrogenase complex, subunit D, integral membrane protein	approved	Hexachlorophene	OC1=C(CC2=C(O)C(Cl)=CC(Cl)=C2Cl)C(Cl)=C(Cl)C=C1Cl
SDHD	DB04141	succinate dehydrogenase complex, subunit D, integral membrane protein	experimental	2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol	CCCCCCO[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O
SDHD	DB08689	succinate dehydrogenase complex, subunit D, integral membrane protein	experimental	UBIQUINONE-1	COC1=C(OC)C(=O)C(CC=C(C)C)=C(C)C1=O
SDS	DB00114	serine dehydratase	nutraceutical	Pyridoxal Phosphate	CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O
SDS	DB00133	serine dehydratase	approved; nutraceutical	L-Serine	N[C@@H](CO)C(O)=O
SGPL1	DB00114	sphingosine-1-phosphate lyase 1	nutraceutical	Pyridoxal Phosphate	CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O
SHMT1	DB00114	serine hydroxymethyltransferase 1 (soluble)	nutraceutical	Pyridoxal Phosphate	CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O
SHMT1	DB00116	serine hydroxymethyltransferase 1 (soluble)	approved; nutraceutical	Tetrahydrofolic acid	NC1=NC(=O)C2=C(NCC(CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)N2)N1
SHMT1	DB00145	serine hydroxymethyltransferase 1 (soluble)	approved; nutraceutical	Glycine	NCC(O)=O
SHMT1	DB01055	serine hydroxymethyltransferase 1 (soluble)	approved	Mimosine	N[C@@H](CN1C=CC(=O)C(O)=C1)C(O)=O
SHMT1	DB02067	serine hydroxymethyltransferase 1 (soluble)	experimental	Triglu-5-Formyl-Tetrahydrofolate	NC1=NC2=C(N(C=O)[C@H](CNC3=CC=C(C=C3)C(=O)N[C@H](CCC(=O)N[C@@H](CCC(=O)N[C@H](CCC(O)=O)C(O)=O)C(O)=O)C(O)=O)CN2)C(=O)N1
SHMT1	DB02800	serine hydroxymethyltransferase 1 (soluble)	experimental	5-Hydroxymethylene-6-Hydrofolic Acid	NC1=NC(=O)C2=C(N1)N=C[C@@H](CNC1=CC=C(C=C1)C(=O)N[C@H](CCC(O)=O)C(O)=O)N2CO
SHMT1	DB02824	serine hydroxymethyltransferase 1 (soluble)	experimental	N-Pyridoxyl-Glycine-5-Monophosphate	CC1=NC=C(COP(O)(O)=O)C(CNCC(O)=O)=C1O
SHMT1	DB00515	serine hydroxymethyltransferase 1 (soluble)	approved	Cisplatin	N[Pt](N)(Cl)Cl
SHMT1	DB00531	serine hydroxymethyltransferase 1 (soluble)	approved; investigational	Cyclophosphamide	ClCCN(CCCl)P1(=O)NCCCO1
SHMT1	DB00970	serine hydroxymethyltransferase 1 (soluble)	approved	Dactinomycin	CC(C)C1NC(=O)C(NC(=O)C2=C3N=C4C(OC3=C(C)C=C2)=C(C)C(=O)C(N)=C4C(=O)NC2C(C)OC(=O)C(C(C)C)N(C)C(=O)CN(C)C(=O)C3CCCN3C(=O)C(NC2=O)C(C)C)C(C)OC(=O)C(C(C)C)N(C)C(=O)CN(C)C(=O)C2CCCN2C1=O
SHMT1	DB00997	serine hydroxymethyltransferase 1 (soluble)	approved; investigational	Doxorubicin	COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3O[C@H]3C[C@H](N)[C@H](O)[C@H](C)O3)C(=O)CO)C(O)=C1C2=O
SHMT1	DB00541	serine hydroxymethyltransferase 1 (soluble)	approved; investigational	Vincristine	CC[C@]1(O)C[C@H]2CN(C1)CCC1=C(NC3=CC=CC=C13)[C@@](C2)(C(=O)OC)C1=C(OC)C=C2N(C=O)[C@@H]3[C@]4(CCN5CC=C[C@](CC)([C@@H]45)[C@@H](OC(C)=O)[C@]3(O)C(=O)OC)C2=C1
SHMT1	DB00133	serine hydroxymethyltransferase 1 (soluble)	approved; nutraceutical	L-Serine	N[C@@H](CO)C(O)=O
SHMT1	DB00563	serine hydroxymethyltransferase 1 (soluble)	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
SHMT1	DB00115	serine hydroxymethyltransferase 1 (soluble)	approved; nutraceutical	Cyanocobalamin	[C@@H]1([C@H]2N3C4=C(C5=[N]6C(C([C@@H]5CCC(N)=O)(C)C)=CC5=[N]7C(=C(C8=[N]([C@@]2([C@@]([C@@H]8CCC(N)=O)(C)CC(N)=O)C)[Co]367([N]2=CN(C3=CC(=C(C)C=C23)C)[C@H]2O[C@H](CO)[C@@H](OP(O)(=O)O[C@H](C)CNC(=O)CC[C@]14C)[C@H]2O)C#N)C)[C@@]([C@@H]5CCC(N)=O)(C)CC(N)=O)C)CC(N)=O
SHMT1	DB00158	serine hydroxymethyltransferase 1 (soluble)	approved; nutraceutical	Folic Acid	NC1=NC(=O)C2=NC(CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)=CN=C2N1
SHMT2	DB00114	serine hydroxymethyltransferase 2 (mitochondrial)	nutraceutical	Pyridoxal Phosphate	CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O
SHMT2	DB00116	serine hydroxymethyltransferase 2 (mitochondrial)	approved; nutraceutical	Tetrahydrofolic acid	NC1=NC(=O)C2=C(NCC(CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)N2)N1
SHMT2	DB00145	serine hydroxymethyltransferase 2 (mitochondrial)	approved; nutraceutical	Glycine	NCC(O)=O
SHMT2	DB00515	serine hydroxymethyltransferase 2 (mitochondrial)	approved	Cisplatin	N[Pt](N)(Cl)Cl
SI	DB00284	sucrase-isomaltase (alpha-glucosidase)	approved; investigational	Acarbose	C[C@H]1O[C@H](O[C@@H]2[C@@H](CO)O[C@H](O[C@@H]3[C@@H](CO)O[C@@H](O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1N[C@H]1C=C(CO)[C@H](O)[C@H](O)[C@H]1O
SI	DB00747	sucrase-isomaltase (alpha-glucosidase)	approved	Scopolamine	CN1C2CC(CC1C1OC21)OC(=O)C(CO)C1=CC=CC=C1
SI	DB04465	sucrase-isomaltase (alpha-glucosidase)	experimental	Lactose	OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O
SLC10A1	DB00145	solute carrier family 10 (sodium/bile acid cotransporter family), member 1	approved; nutraceutical	Glycine	NCC(O)=O
SLC10A1	DB01098	solute carrier family 10 (sodium/bile acid cotransporter family), member 1	approved	Rosuvastatin	CC(C)C1=NC(=NC(C2=CC=C(F)C=C2)=C1\C=C\[C@H](O)C[C@@H](O)CC(O)=O)N(C)S(=O)(=O)C
SLC10A2	DB01248	solute carrier family 10 (sodium/bile acid cotransporter family), member 2	approved; investigational	Docetaxel	CC(=O)O[C@@]12CO[C@@H]1C[C@H](O)[C@]1(C)[C@@H]2[C@H](OC(=O)C2=CC=CC=C2)[C@]2(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C3=CC=CC=C3)C(C)=C([C@@H](O)C1=O)C2(C)C
SLC10A2	DB01041	solute carrier family 10 (sodium/bile acid cotransporter family), member 2	approved; withdrawn; investigational	Thalidomide	O=C1N(C2CCC(=O)NC2=O)C(=O)C2=CC=CC=C12
SLC10A2	DB00145	solute carrier family 10 (sodium/bile acid cotransporter family), member 2	approved; nutraceutical	Glycine	NCC(O)=O
SLC16A1	DB00119	solute carrier family 16, member 1 (monocarboxylic acid transporter 1)	approved; nutraceutical	Pyruvic acid	CC(=O)C(O)=O
SLC16A3	DB00119	solute carrier family 16, member 3 (monocarboxylic acid transporter 4)	approved; nutraceutical	Pyruvic acid	CC(=O)C(O)=O
SLC16A4	DB00119	solute carrier family 16, member 4 (monocarboxylic acid transporter 5)	approved; nutraceutical	Pyruvic acid	CC(=O)C(O)=O
SLC16A8	DB00119	solute carrier family 16, member 8 (monocarboxylic acid transporter 3)	approved; nutraceutical	Pyruvic acid	CC(=O)C(O)=O
SLC19A1	DB01234	solute carrier family 19 (folate transporter), member 1	approved; investigational	Dexamethasone	C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
SLC19A1	DB00515	solute carrier family 19 (folate transporter), member 1	approved	Cisplatin	N[Pt](N)(Cl)Cl
SLC19A1	DB00531	solute carrier family 19 (folate transporter), member 1	approved; investigational	Cyclophosphamide	ClCCN(CCCl)P1(=O)NCCCO1
SLC19A1	DB00970	solute carrier family 19 (folate transporter), member 1	approved	Dactinomycin	CC(C)C1NC(=O)C(NC(=O)C2=C3N=C4C(OC3=C(C)C=C2)=C(C)C(=O)C(N)=C4C(=O)NC2C(C)OC(=O)C(C(C)C)N(C)C(=O)CN(C)C(=O)C3CCCN3C(=O)C(NC2=O)C(C)C)C(C)OC(=O)C(C(C)C)N(C)C(=O)CN(C)C(=O)C2CCCN2C1=O
SLC19A1	DB00997	solute carrier family 19 (folate transporter), member 1	approved; investigational	Doxorubicin	COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3O[C@H]3C[C@H](N)[C@H](O)[C@H](C)O3)C(=O)CO)C(O)=C1C2=O
SLC19A1	DB01611	solute carrier family 19 (folate transporter), member 1	approved	Hydroxychloroquine	CCN(CCO)CCCC(C)NC1=C2C=CC(Cl)=CC2=NC=C1
SLC19A1	DB00795	solute carrier family 19 (folate transporter), member 1	approved	Sulfasalazine	OC(=O)C1=CC(=CC=C1O)\N=N\C1=CC=C(C=C1)S(=O)(=O)NC1=NC=CC=C1
SLC19A1	DB00145	solute carrier family 19 (folate transporter), member 1	approved; nutraceutical	Glycine	NCC(O)=O
SLC19A1	DB00133	solute carrier family 19 (folate transporter), member 1	approved; nutraceutical	L-Serine	N[C@@H](CO)C(O)=O
SLC19A1	DB00293	solute carrier family 19 (folate transporter), member 1	approved; investigational	Raltitrexed	CN(CC1=CC2=C(NC(C)=NC2=O)C=C1)C1=CC=C(S1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
SLC19A1	DB00158	solute carrier family 19 (folate transporter), member 1	approved; nutraceutical	Folic Acid	NC1=NC(=O)C2=NC(CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)=CN=C2N1
SLC19A1	DB00987	solute carrier family 19 (folate transporter), member 1	approved; investigational	Cytarabine	NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O
SLC19A1	DB00694	solute carrier family 19 (folate transporter), member 1	approved	Daunorubicin	COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3O[C@H]3C[C@H](N)[C@H](O)[C@H](C)O3)C(C)=O)C(O)=C1C2=O
SLC19A1	DB00773	solute carrier family 19 (folate transporter), member 1	approved	Etoposide	COC1=CC(=CC(OC)=C1O)[C@H]1[C@@H]2[C@H](COC2=O)[C@H](O[C@@H]2O[C@@H]3CO[C@@H](C)O[C@H]3[C@H](O)[C@H]2O)C2=CC3=C(OCO3)C=C12
SLC19A1	DB00650	solute carrier family 19 (folate transporter), member 1	approved	Leucovorin	NC1=NC(=O)C2=C(NCC(CNC3=CC=C(C=C3)C(=O)N[C@H](CCC(O)=O)C(O)=O)N2C=O)N1
SLC19A1	DB01033	solute carrier family 19 (folate transporter), member 1	approved	Mercaptopurine	S=C1N=CNC2=C1NC=N2
SLC19A1	DB00563	solute carrier family 19 (folate transporter), member 1	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
SLC19A1	DB00635	solute carrier family 19 (folate transporter), member 1	approved	Prednisone	C[C@]12CC(=O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
SLC19A1	DB00541	solute carrier family 19 (folate transporter), member 1	approved; investigational	Vincristine	CC[C@]1(O)C[C@H]2CN(C1)CCC1=C(NC3=CC=CC=C13)[C@@](C2)(C(=O)OC)C1=C(OC)C=C2N(C=O)[C@@H]3[C@]4(CCN5CC=C[C@](CC)([C@@H]45)[C@@H](OC(C)=O)[C@]3(O)C(=O)OC)C2=C1
SLC19A1	DB00544	solute carrier family 19 (folate transporter), member 1	approved	Fluorouracil	FC1=CNC(=O)NC1=O
SLC19A1	DB00762	solute carrier family 19 (folate transporter), member 1	approved; investigational	Irinotecan	CCC1=C2CN3C(=CC4=C(COC(=O)[C@]4(O)CC)C3=O)C2=NC2=C1C=C(OC(=O)N1CCC(CC1)N1CCCCC1)C=C2
SLC19A1	DB00958	solute carrier family 19 (folate transporter), member 1	approved	Carboplatin	N.N.O=C1O[Pt]OC(=O)C11CCC1
SLC19A1	DB00642	solute carrier family 19 (folate transporter), member 1	approved; investigational	Pemetrexed	NC1=NC(=O)C2=C(NC=C2CCC2=CC=C(C=C2)C(=O)N[C@H](CCC(O)=O)C(O)=O)N1
SLC19A2	DB00152	solute carrier family 19 (thiamine transporter), member 2	approved; nutraceutical	Thiamine	CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N
SLC19A3	DB00151	solute carrier family 19, member 3	approved; nutraceutical	L-Cysteine	N[C@@H](CS)C(O)=O
SLC19A3	DB00997	solute carrier family 19, member 3	approved; investigational	Doxorubicin	COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3O[C@H]3C[C@H](N)[C@H](O)[C@H](C)O3)C(=O)CO)C(O)=C1C2=O
SLC22A1	DB00331	solute carrier family 22 (organic cation transporter), member 1	approved	Metformin	CN(C)C(=N)NC(N)=N
SLC22A1	DB00193	solute carrier family 22 (organic cation transporter), member 1	approved; investigational	Tramadol	COC1=CC=CC(=C1)[C@@]1(O)CCCC[C@@H]1CN(C)C
SLC22A1	DB00619	solute carrier family 22 (organic cation transporter), member 1	approved	Imatinib	CN1CCN(CC2=CC=C(C=C2)C(=O)NC2=CC(NC3=NC=CC(=N3)C3=CN=CC=C3)=C(C)C=C2)CC1
SLC22A1	DB00958	solute carrier family 22 (organic cation transporter), member 1	approved	Carboplatin	N.N.O=C1O[Pt]OC(=O)C11CCC1
SLC22A1	DB00515	solute carrier family 22 (organic cation transporter), member 1	approved	Cisplatin	N[Pt](N)(Cl)Cl
SLC22A1	DB00526	solute carrier family 22 (organic cation transporter), member 1	approved; investigational	Oxaliplatin	O=C1O[Pt]2(N[C@@H]3CCCC[C@H]3N2)OC1=O
SLC22A1	DB00321	solute carrier family 22 (organic cation transporter), member 1	approved	Amitriptyline	CN(C)CCC=C1C2=CC=CC=C2CCC2=CC=CC=C12
SLC22A1	DB00661	solute carrier family 22 (organic cation transporter), member 1	approved	Verapamil	COC1=C(OC)C=C(CCN(C)CCCC(C#N)(C(C)C)C2=CC(OC)=C(OC)C=C2)C=C1
SLC22A1	DB01045	solute carrier family 22 (organic cation transporter), member 1	approved	Rifampin	CO[C@H]1\C=C\O[C@@]2(C)OC3=C(C)C(O)=C4C(O)=C(NC(=O)\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@H](O)[C@H](C)[C@H](OC(C)=O)[C@@H]1C)C(\C=N\N1CCN(C)CC1)=C(O)C4=C3C2=O
SLC22A1	DB00787	solute carrier family 22 (organic cation transporter), member 1	approved	Aciclovir	NC1=NC(=O)C2=C(N1)N(COCCO)C=N2
SLC22A1	DB00879	solute carrier family 22 (organic cation transporter), member 1	approved; investigational	Emtricitabine	NC1=NC(=O)N(C=C1F)[C@@H]1CS[C@H](CO)O1
SLC22A1	DB00709	solute carrier family 22 (organic cation transporter), member 1	approved; investigational	Lamivudine	NC1=NC(=O)N(C=C1)[C@@H]1CS[C@H](CO)O1
SLC22A1	DB00495	solute carrier family 22 (organic cation transporter), member 1	approved	Zidovudine	CC1=CN([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2)C(=O)NC1=O
SLC22A2	DB00331	solute carrier family 22 (organic cation transporter), member 2	approved	Metformin	CN(C)C(=N)NC(N)=N
SLC22A2	DB00690	solute carrier family 22 (organic cation transporter), member 2	illicit; approved	Flurazepam	CCN(CC)CCN1C2=C(C=C(Cl)C=C2)C(=NCC1=O)C1=CC=CC=C1F
SLC22A2	DB00988	solute carrier family 22 (organic cation transporter), member 2	approved	Dopamine	NCCC1=CC(O)=C(O)C=C1
SLC22A2	DB00126	solute carrier family 22 (organic cation transporter), member 2	approved; nutraceutical	Vitamin C	OC[C@H](O)[C@H]1OC(=O)C(O)=C1O
SLC22A2	DB00122	solute carrier family 22 (organic cation transporter), member 2	approved; nutraceutical	Choline	C[N+](C)(C)CCO
SLC22A2	DB00501	solute carrier family 22 (organic cation transporter), member 2	approved	Cimetidine	C\N=C(\NCCSCC1=C(C)NC=N1)NC#N
SLC22A2	DB00958	solute carrier family 22 (organic cation transporter), member 2	approved	Carboplatin	N.N.O=C1O[Pt]OC(=O)C11CCC1
SLC22A2	DB00515	solute carrier family 22 (organic cation transporter), member 2	approved	Cisplatin	N[Pt](N)(Cl)Cl
SLC22A2	DB00526	solute carrier family 22 (organic cation transporter), member 2	approved; investigational	Oxaliplatin	O=C1O[Pt]2(N[C@@H]3CCCC[C@H]3N2)OC1=O
SLC22A2	DB01273	solute carrier family 22 (organic cation transporter), member 2	approved; investigational	Varenicline	C1[C@H]2CNC[C@@H]1C1=CC3=NC=CN=C3C=C21
SLC22A2	DB00879	solute carrier family 22 (organic cation transporter), member 2	approved; investigational	Emtricitabine	NC1=NC(=O)N(C=C1F)[C@@H]1CS[C@H](CO)O1
SLC22A2	DB00709	solute carrier family 22 (organic cation transporter), member 2	approved; investigational	Lamivudine	NC1=NC(=O)N(C=C1)[C@@H]1CS[C@H](CO)O1
SLC22A2	DB00495	solute carrier family 22 (organic cation transporter), member 2	approved	Zidovudine	CC1=CN([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2)C(=O)NC1=O
SLC22A3	DB00331	solute carrier family 22 (extraneuronal monoamine transporter), member 3	approved	Metformin	CN(C)C(=N)NC(N)=N
SLC22A3	DB00368	solute carrier family 22 (extraneuronal monoamine transporter), member 3	approved	Norepinephrine	NC[C@H](O)C1=CC(O)=C(O)C=C1
SLC22A3	DB00879	solute carrier family 22 (extraneuronal monoamine transporter), member 3	approved; investigational	Emtricitabine	NC1=NC(=O)N(C=C1F)[C@@H]1CS[C@H](CO)O1
SLC22A3	DB00709	solute carrier family 22 (extraneuronal monoamine transporter), member 3	approved; investigational	Lamivudine	NC1=NC(=O)N(C=C1)[C@@H]1CS[C@H](CO)O1
SLC22A3	DB00495	solute carrier family 22 (extraneuronal monoamine transporter), member 3	approved	Zidovudine	CC1=CN([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2)C(=O)NC1=O
SLC23A1	DB00126	solute carrier family 23 (nucleobase transporters), member 1	approved; nutraceutical	Vitamin C	OC[C@H](O)[C@H]1OC(=O)C(O)=C1O
SLC25A1	DB00121	solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1	approved; nutraceutical	Biotin	OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12
SLC25A10	DB00139	solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10	approved; nutraceutical	Succinic acid	OC(=O)CCC(O)=O
SLC25A10	DB00121	solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10	approved; nutraceutical	Biotin	OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12
SLC25A11	DB00121	solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11	approved; nutraceutical	Biotin	OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12
SLC25A12	DB00128	solute carrier family 25 (aspartate/glutamate carrier), member 12	approved; nutraceutical	L-Aspartic Acid	N[C@@H](CC(O)=O)C(O)=O
SLC25A13	DB00128	solute carrier family 25 (aspartate/glutamate carrier), member 13	approved; nutraceutical	L-Aspartic Acid	N[C@@H](CC(O)=O)C(O)=O
SLC25A15	DB00129	solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15	approved; nutraceutical	L-Ornithine	NCCC[C@H](N)C(O)=O
SLC25A16	DB00151	solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16	approved; nutraceutical	L-Cysteine	N[C@@H](CS)C(O)=O
SLC25A2	DB00129	solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2	approved; nutraceutical	L-Ornithine	NCCC[C@H](N)C(O)=O
SLC25A20	DB00583	solute carrier family 25 (carnitine/acylcarnitine translocase), member 20	approved	L-Carnitine	C[N+](C)(C)C[C@H](O)CC([O-])=O
SLC25A21	DB00123	solute carrier family 25 (mitochondrial oxoadipate carrier), member 21	approved; nutraceutical	L-Lysine	NCCCC[C@H](N)C(O)=O
SLC25A32	DB00145	solute carrier family 25 (mitochondrial folate carrier), member 32	approved; nutraceutical	Glycine	NCC(O)=O
SLC25A32	DB00133	solute carrier family 25 (mitochondrial folate carrier), member 32	approved; nutraceutical	L-Serine	N[C@@H](CO)C(O)=O
SLC25A4	DB00171	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
SLC25A4	DB00720	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4	approved; investigational	Clodronate	OP(O)(=O)C(Cl)(Cl)P(O)(O)=O
SLC25A4	DB01736	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4	experimental	[3-(Dodecanoylamino)Propyl](Hydroxy)Dimethylammonium	CCCCCCCCCCCC(=O)NCCC[N+](C)(C)[O-]
SLC25A4	DB02426	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4	experimental	Carboxyatractyloside	CC(C)CC(=O)O[C@H]1[C@@H](O[C@@H]2C[C@]3(C)[C@H]4CC[C@@H]5C[C@@]4(CC[C@H]3C(C2)(C(O)=O)C(O)=O)[C@@H](O)C5=C)O[C@@H](COO)[C@H](OS(O)(=O)=O)[C@@H]1OS(O)(=O)=O
SLC25A4	DB03429	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4	experimental	Cardiolipin	CCCCCCCCCCCCCCCCCC(=O)OC[C@H](CO[P@@](O)(=O)OCC(O)CO[P@](O)(=O)OC[C@@H](COC(=O)CCCCCCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCCCCCC
SLC25A4	DB04178	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4	experimental	Di-Stearoyl-3-Sn-Phosphatidylcholine	CCCCCCCCCCCCCCCCCC(=O)OC[C@@H](CO[P@@](O)(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCCCCCCCCCCC
SLC25A5	DB00720	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5	approved; investigational	Clodronate	OP(O)(=O)C(Cl)(Cl)P(O)(O)=O
SLC25A6	DB00720	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6	approved; investigational	Clodronate	OP(O)(=O)C(Cl)(Cl)P(O)(O)=O
SLC27A2	DB00145	solute carrier family 27 (fatty acid transporter), member 2	approved; nutraceutical	Glycine	NCC(O)=O
SLC27A5	DB00145	solute carrier family 27 (fatty acid transporter), member 5	approved; nutraceutical	Glycine	NCC(O)=O
SLC2A1	DB00318	solute carrier family 2 (facilitated glucose transporter), member 1	illicit; approved	Codeine	COC1=C2O[C@H]3[C@@H](O)C=C[C@H]4[C@H]5CC(C=C1)=C2[C@@]34CCN5C
SLC2A1	DB00295	solute carrier family 2 (facilitated glucose transporter), member 1	approved; investigational	Morphine	CN1CC[C@]23[C@H]4OC5=C(O)C=CC(C[C@@H]1[C@@H]2C=C[C@@H]4O)=C35
SLC2A2	DB00121	solute carrier family 2 (facilitated glucose transporter), member 2	approved; nutraceutical	Biotin	OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12
SLC2A4	DB00122	solute carrier family 2 (facilitated glucose transporter), member 4	approved; nutraceutical	Choline	C[N+](C)(C)CCO
SLC37A4	DB00121	solute carrier family 37 (glucose-6-phosphate transporter), member 4	approved; nutraceutical	Biotin	OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12
SLC46A1	DB00145	solute carrier family 46 (folate transporter), member 1	approved; nutraceutical	Glycine	NCC(O)=O
SLC46A1	DB00133	solute carrier family 46 (folate transporter), member 1	approved; nutraceutical	L-Serine	N[C@@H](CO)C(O)=O
SLC46A1	DB00563	solute carrier family 46 (folate transporter), member 1	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
SLC46A1	DB00158	solute carrier family 46 (folate transporter), member 1	approved; nutraceutical	Folic Acid	NC1=NC(=O)C2=NC(CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)=CN=C2N1
SLC5A1	DB01212	solute carrier family 5 (sodium/glucose cotransporter), member 1	approved	Ceftriaxone	CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(CSC3=NC(=O)C(=O)NN3C)=C(N2C1=O)C(O)=O)C1=CSC(N)=N1
SLC5A5	DB00135	solute carrier family 5 (sodium iodide symporter), member 5	approved; nutraceutical	L-Tyrosine	N[C@@H](CC1=CC=C(O)C=C1)C(O)=O
SLC5A5	DB00531	solute carrier family 5 (sodium iodide symporter), member 5	approved; investigational	Cyclophosphamide	ClCCN(CCCl)P1(=O)NCCCO1
SLC5A6	DB00121	solute carrier family 5 (sodium-dependent vitamin transporter), member 6	approved; nutraceutical	Biotin	OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12
SLC5A6	DB00166	solute carrier family 5 (sodium-dependent vitamin transporter), member 6	approved; nutraceutical	Lipoic Acid	OC(=O)CCCC[C@@H]1CCSS1
SLC6A8	DB00148	solute carrier family 6 (neurotransmitter transporter, creatine), member 8	approved; nutraceutical	Creatine	CN(CC(O)=O)C(N)=N
SLC6A8	DB00515	solute carrier family 6 (neurotransmitter transporter, creatine), member 8	approved	Cisplatin	N[Pt](N)(Cl)Cl
SLC9A1	DB00594	solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1	approved	Amiloride	NC(N)=NC(=O)C1=C(N)N=C(N)C(Cl)=N1
SLC9A1	DB02624	solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1	experimental	Homoserine Lactone	N[C@@H]1CCOC1=O
SLCO1A2	DB00286	solute carrier organic anion transporter family, member 1A2	approved	Conjugated Estrogens	[Na+].C[C@]12CC[C@H]3[C@@H](CCC4=CC(OS([O-])(=O)=O)=CC=C34)[C@@H]1CCC2=O
SLCO1A2	DB00563	solute carrier organic anion transporter family, member 1A2	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
SLCO1A2	DB00537	solute carrier organic anion transporter family, member 1A2	approved; investigational	Ciprofloxacin	OC(=O)C1=CN(C2CC2)C2=CC(N3CCNCC3)=C(F)C=C2C1=O
SLCO1A2	DB00467	solute carrier organic anion transporter family, member 1A2	approved	Enoxacin	CCN1C=C(C(O)=O)C(=O)C2=CC(F)=C(N=C12)N1CCNCC1
SLCO1A2	DB01044	solute carrier organic anion transporter family, member 1A2	approved; investigational	Gatifloxacin	COC1=C2N(C=C(C(O)=O)C(=O)C2=CC(F)=C1N1CCNC(C)C1)C1CC1
SLCO1A2	DB01137	solute carrier organic anion transporter family, member 1A2	approved; investigational	Levofloxacin	C[C@H]1COC2=C3N1C=C(C(O)=O)C(=O)C3=CC(F)=C2N1CCN(C)CC1
SLCO1A2	DB00279	solute carrier organic anion transporter family, member 1A2	approved	Liothyronine	N[C@@H](CC1=CC(I)=C(OC2=CC(I)=C(O)C=C2)C(I)=C1)C(O)=O
SLCO1A2	DB00978	solute carrier organic anion transporter family, member 1A2	approved	Lomefloxacin	CCN1C=C(C(O)=O)C(=O)C2=CC(F)=C(N3CCNC(C)C3)C(F)=C12
SLCO1A2	DB01059	solute carrier organic anion transporter family, member 1A2	approved	Norfloxacin	CCN1C=C(C(O)=O)C(=O)C2=CC(F)=C(C=C12)N1CCNCC1
SLCO1A2	DB00728	solute carrier organic anion transporter family, member 1A2	approved	Rocuronium	CC(=O)O[C@H]1[C@H](C[C@H]2[C@@H]3CC[C@H]4C[C@H](O)[C@H](C[C@]4(C)[C@H]3CC[C@]12C)N1CCOCC1)[N+]1(CC=C)CCCC1
SLCO1A2	DB01098	solute carrier organic anion transporter family, member 1A2	approved	Rosuvastatin	CC(C)C1=NC(=NC(C2=CC=C(F)C=C2)=C1\C=C\[C@H](O)C[C@@H](O)CC(O)=O)N(C)S(=O)(=O)C
SLCO1A2	DB01232	solute carrier organic anion transporter family, member 1A2	approved; investigational	Saquinavir	CC(C)(C)NC(=O)[C@@H]1CC2CCCCC2CN1C[C@@H](O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CC(N)=O)NC(=O)C1=NC2=CC=CC=C2C=C1
SLCO1A2	DB00619	solute carrier organic anion transporter family, member 1A2	approved	Imatinib	CN1CCN(CC2=CC=C(C=C2)C(=O)NC2=CC(NC3=NC=CC(=N3)C3=CN=CC=C3)=C(C)C=C2)CC1
SLCO1A2	DB01092	solute carrier organic anion transporter family, member 1A2	approved	Ouabain	C[C@@H]1O[C@@H](O[C@H]2C[C@@H](O)[C@]3(CO)[C@H]4[C@H](O)C[C@]5(C)[C@H](CC[C@]5(O)[C@@H]4CC[C@]3(O)C2)C2=CC(=O)OC2)[C@H](O)[C@H](O)[C@H]1O
SLCO1A2	DB00175	solute carrier organic anion transporter family, member 1A2	approved	Pravastatin	CC[C@H](C)C(=O)O[C@H]1C[C@H](O)C=C2C=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC(O)=O)[C@@H]12
SLCO1A2	DB00199	solute carrier organic anion transporter family, member 1A2	approved	Erythromycin	CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O
SLCO1A2	DB00145	solute carrier organic anion transporter family, member 1A2	approved; nutraceutical	Glycine	NCC(O)=O
SLCO1A2	DB01601	solute carrier organic anion transporter family, member 1A2	approved	Lopinavir	CC(C)[C@H](N1CCCNC1=O)C(=O)N[C@H](C[C@H](O)[C@H](CC1=CC=CC=C1)NC(=O)COC1=C(C)C=CC=C1C)CC1=CC=CC=C1
SLCO1A2	DB00950	solute carrier organic anion transporter family, member 1A2	approved	Fexofenadine	CC(C)(C(O)=O)C1=CC=C(C=C1)C(O)CCCN1CCC(CC1)C(O)(C1=CC=CC=C1)C1=CC=CC=C1
SLCO1A2	DB00564	solute carrier organic anion transporter family, member 1A2	approved; investigational	Carbamazepine	NC(=O)N1C2=CC=CC=C2C=CC2=CC=CC=C12
SLCO1B1	DB01169	solute carrier organic anion transporter family, member 1B1	approved; investigational	Arsenic trioxide	O1[As]2O[As]1O2
SLCO1B1	DB00279	solute carrier organic anion transporter family, member 1B1	approved	Liothyronine	N[C@@H](CC1=CC(I)=C(OC2=CC(I)=C(O)C=C2)C(I)=C1)C(O)=O
SLCO1B1	DB01053	solute carrier organic anion transporter family, member 1B1	approved	Penicillin G	CC1(C)S[C@@H]2[C@H](NC(=O)CC3=CC=CC=C3)C(=O)N2[C@H]1C(O)=O
SLCO1B1	DB00688	solute carrier organic anion transporter family, member 1B1	approved; investigational	Mycophenolate mofetil	COC1=C(C\C=C(/C)CCC(=O)OCCN2CCOCC2)C(O)=C2C(=O)OCC2=C1C
SLCO1B1	DB00877	solute carrier organic anion transporter family, member 1B1	approved; investigational	Sirolimus	CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1O
SLCO1B1	DB00683	solute carrier organic anion transporter family, member 1B1	illicit; approved	Midazolam	CC1=NC=C2CN=C(C3=CC=CC=C3F)C3=C(C=CC(Cl)=C3)N12
SLCO1B1	DB01016	solute carrier organic anion transporter family, member 1B1	approved	Glyburide	COC1=C(C=C(Cl)C=C1)C(=O)NCCC1=CC=C(C=C1)S(=O)(=O)NC(=O)NC1CCCCC1
SLCO1B1	DB00257	solute carrier organic anion transporter family, member 1B1	approved	Clotrimazole	ClC1=CC=CC=C1C(N1C=CN=C1)(C1=CC=CC=C1)C1=CC=CC=C1
SLCO1B1	DB00834	solute carrier organic anion transporter family, member 1B1	approved; investigational	Mifepristone	CC#C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]12C)C1=CC=C(C=C1)N(C)C
SLCO1B1	DB01229	solute carrier organic anion transporter family, member 1B1	approved	Paclitaxel	CC(=O)O[C@@H]1C2=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)C3=CC=CC=C3)[C@@H]3[C@@]4(CO[C@@H]4C[C@H](O)[C@@]3(C)C1=O)OC(C)=O)C2(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)C1=CC=CC=C1)C1=CC=CC=C1
SLCO1B1	DB00197	solute carrier organic anion transporter family, member 1B1	withdrawn	Troglitazone	CC1=C(C)C2=C(CCC(C)(COC3=CC=C(CC4SC(=O)NC4=O)C=C3)O2)C(C)=C1O
SLCO1B1	DB00177	solute carrier organic anion transporter family, member 1B1	approved; investigational	Valsartan	CCCCC(=O)N(CC1=CC=C(C=C1)C1=CC=CC=C1C1=NNN=N1)[C@@H](C(C)C)C(O)=O
SLCO1B1	DB00342	solute carrier organic anion transporter family, member 1B1	approved; withdrawn	Terfenadine	CC(C)(C)C1=CC=C(C=C1)C(O)CCCN1CCC(CC1)C(O)(C1=CC=CC=C1)C1=CC=CC=C1
SLCO1B1	DB00520	solute carrier organic anion transporter family, member 1B1	approved	Caspofungin	CCC(C)CC(C)CCCCCCCCC(=O)N[C@H]1C[C@@H](O)[C@@H](NCCN)NC(=O)[C@@H]2[C@@H](O)CCN2C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC1=O)[C@@H](C)O)[C@H](O)[C@@H](O)C1=CC=C(O)C=C1)[C@H](O)CCN
SLCO1B1	DB00917	solute carrier organic anion transporter family, member 1B1	approved	Dinoprostone	CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O
SLCO1B1	DB01132	solute carrier organic anion transporter family, member 1B1	approved; investigational	Pioglitazone	CCC1=CN=C(CCOC2=CC=C(CC3SC(=O)NC3=O)C=C2)C=C1
SLCO1B1	DB00275	solute carrier organic anion transporter family, member 1B1	approved; investigational	Olmesartan	CCCC1=NC(=C(N1CC1=CC=C(C=C1)C1=CC=CC=C1C1=NNN=N1)C(=O)OCC1=C(C)OC(=O)O1)C(C)(C)O
SLCO1B1	DB00563	solute carrier organic anion transporter family, member 1B1	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
SLCO1B1	DB00584	solute carrier organic anion transporter family, member 1B1	approved	Enalapril	CCOC(=O)[C@@H](CCC1=CC=CC=C1)N[C@@H](C)C(=O)N1CCC[C@H]1C(O)=O
SLCO1B1	DB00471	solute carrier organic anion transporter family, member 1B1	approved	Montelukast	OC(=O)CC1(CC1)CS[C@H](CCC1=CC=CC=C1C(O)(C)C)C1=CC=CC(\C=C\C2=NC3=C(C=CC(Cl)=C3)C=C2)=C1
SLCO1B1	DB00318	solute carrier organic anion transporter family, member 1B1	illicit; approved	Codeine	COC1=C2O[C@H]3[C@@H](O)C=C[C@H]4[C@H]5CC(C=C1)=C2[C@@]34CCN5C
SLCO1B1	DB00295	solute carrier organic anion transporter family, member 1B1	approved; investigational	Morphine	CN1CC[C@]23[C@H]4OC5=C(O)C=CC(C[C@@H]1[C@@H]2C=C[C@@H]4O)=C35
SLCO1B1	DB00731	solute carrier organic anion transporter family, member 1B1	approved; investigational	Nateglinide	CC(C)C1CC[C@@H](CC1)C(=O)N[C@H](CC1=CC=CC=C1)C(O)=O
SLCO1B1	DB00412	solute carrier organic anion transporter family, member 1B1	approved; investigational	Rosiglitazone	CN(CCOC1=CC=C(CC2SC(=O)NC2=O)C=C1)C1=CC=CC=N1
SLCO1B1	DB00145	solute carrier organic anion transporter family, member 1B1	approved; nutraceutical	Glycine	NCC(O)=O
SLCO1B1	DB00390	solute carrier organic anion transporter family, member 1B1	approved	Digoxin	C[C@H]1O[C@H](C[C@H](O)[C@@H]1O)O[C@H]1[C@@H](O)C[C@H](O[C@H]2[C@@H](O)C[C@H](O[C@H]3CC[C@@]4(C)[C@H](CC[C@@H]5[C@@H]4C[C@@H](O)[C@]4(C)C(CC[C@]54O)C4=CC(=O)OC4)C3)O[C@@H]2C)O[C@@H]1C
SLCO1B1	DB01601	solute carrier organic anion transporter family, member 1B1	approved	Lopinavir	CC(C)[C@H](N1CCCNC1=O)C(=O)N[C@H](C[C@H](O)[C@H](CC1=CC=CC=C1)NC(=O)COC1=C(C)C=CC=C1C)CC1=CC=CC=C1
SLCO1B1	DB00641	solute carrier organic anion transporter family, member 1B1	approved	Simvastatin	CCC(C)(C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CCC3C[C@@H](O)CC(=O)O3)[C@@H]12
SLCO1B1	DB01076	solute carrier organic anion transporter family, member 1B1	approved	Atorvastatin	CC(C)C1=C(C(=O)NC2=CC=CC=C2)C(=C(N1CC[C@@H](O)C[C@@H](O)CC(O)=O)C1=CC=C(F)C=C1)C1=CC=CC=C1
SLCO1B1	DB00439	solute carrier organic anion transporter family, member 1B1	withdrawn	Cerivastatin	COCC1=C(C2=CC=C(F)C=C2)C(\C=C\[C@@H](O)C[C@@H](O)CC(O)=O)=C(C(C)C)N=C1C(C)C
SLCO1B1	DB00343	solute carrier organic anion transporter family, member 1B1	approved	Diltiazem	COC1=CC=C(C=C1)[C@@H]1SC2=CC=CC=C2N(CCN(C)C)C(=O)[C@@H]1OC(C)=O
SLCO1B1	DB01241	solute carrier organic anion transporter family, member 1B1	approved	Gemfibrozil	CC1=CC(OCCCC(C)(C)C(O)=O)=C(C)C=C1
SLCO1B1	DB01167	solute carrier organic anion transporter family, member 1B1	approved; investigational	Itraconazole	CCC(C)N1N=CN(C1=O)C1=CC=C(C=C1)N1CCN(CC1)C1=CC=C(OC[C@H]2CO[C@@](CN3C=NC=N3)(O2)C2=C(Cl)C=C(Cl)C=C2)C=C1
SLCO1B1	DB00227	solute carrier organic anion transporter family, member 1B1	approved; investigational	Lovastatin	CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12
SLCO1B1	DB00503	solute carrier organic anion transporter family, member 1B1	approved; investigational	Ritonavir	CC(C)[C@H](NC(=O)N(C)CC1=CSC(=N1)C(C)C)C(=O)N[C@H](C[C@H](O)[C@H](CC1=CC=CC=C1)NC(=O)OCC1=CN=CS1)CC1=CC=CC=C1
SLCO1B1	DB00661	solute carrier organic anion transporter family, member 1B1	approved	Verapamil	COC1=C(OC)C=C(CCN(C)CCCC(C#N)(C(C)C)C2=CC(OC)=C(OC)C=C2)C=C1
SLCO1B1	DB00783	solute carrier organic anion transporter family, member 1B1	approved; investigational	Estradiol	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CC[C@@H]2O
SLCO1B1	DB00559	solute carrier organic anion transporter family, member 1B1	approved; investigational	Bosentan	COC1=CC=CC=C1OC1=C(NS(=O)(=O)C2=CC=C(C=C2)C(C)(C)C)N=C(N=C1OCCO)C1=NC=CC=N1
SLCO1B1	DB00950	solute carrier organic anion transporter family, member 1B1	approved	Fexofenadine	CC(C)(C(O)=O)C1=CC=C(C=C1)C(O)CCCN1CCC(CC1)C(O)(C1=CC=CC=C1)C1=CC=CC=C1
SLCO1B1	DB00718	solute carrier organic anion transporter family, member 1B1	approved; investigational	Adefovir Dipivoxil	CC(C)(C)C(=O)OCOP(=O)(COCCN1C=NC2=C(N)N=CN=C12)OCOC(=O)C(C)(C)C
SLCO1B1	DB00501	solute carrier organic anion transporter family, member 1B1	approved	Cimetidine	C\N=C(\NCCSCC1=C(C)NC=N1)NC#N
SLCO1B1	DB00762	solute carrier organic anion transporter family, member 1B1	approved; investigational	Irinotecan	CCC1=C2CN3C(=CC4=C(COC(=O)[C@]4(O)CC)C3=O)C2=NC2=C1C=C(OC(=O)N1CCC(CC1)N1CCCCC1)C=C2
SLCO1B1	DB00912	solute carrier organic anion transporter family, member 1B1	approved; investigational	Repaglinide	CCOC1=C(C=CC(CC(=O)N[C@@H](CC(C)C)C2=CC=CC=C2N2CCCCC2)=C1)C(O)=O
SLCO1B1	DB01098	solute carrier organic anion transporter family, member 1B1	approved	Rosuvastatin	CC(C)C1=NC(=NC(C2=CC=C(F)C=C2)=C1\C=C\[C@H](O)C[C@@H](O)CC(O)=O)N(C)S(=O)(=O)C
SLCO1B1	DB00973	solute carrier organic anion transporter family, member 1B1	approved	Ezetimibe	O[C@@H](CC[C@@H]1[C@H](N(C1=O)C1=CC=C(F)C=C1)C1=CC=C(O)C=C1)C1=CC=C(F)C=C1
SLCO1B1	DB01045	solute carrier organic anion transporter family, member 1B1	approved	Rifampin	CO[C@H]1\C=C\O[C@@]2(C)OC3=C(C)C(O)=C4C(O)=C(NC(=O)\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@H](O)[C@H](C)[C@H](OC(C)=O)[C@@H]1C)C(\C=N\N1CCN(C)CC1)=C(O)C4=C3C2=O
SLCO1B1	DB01095	solute carrier organic anion transporter family, member 1B1	approved	Fluvastatin	CC(C)N1C(\C=C\[C@H](O)C[C@H](O)CC(O)=O)=C(C2=CC=C(F)C=C2)C2=CC=CC=C12
SLCO1B1	DB00175	solute carrier organic anion transporter family, member 1B1	approved	Pravastatin	CC[C@H](C)C(=O)O[C@H]1C[C@H](O)C=C2C=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC(O)=O)[C@@H]12
SLCO1B1	DB00864	solute carrier organic anion transporter family, member 1B1	approved; investigational	Tacrolimus	CO[C@@H]1C[C@@H](CC[C@H]1O)\C=C(/C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H]([C@H](C[C@H]2C)OC)[C@H](C[C@@H](C)C\C(C)=C\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]1C)OC
SLCO1B1	DB01026	solute carrier organic anion transporter family, member 1B1	approved; investigational	Ketoconazole	CC(=O)N1CCN(CC1)C1=CC=C(OC[C@@H]2CO[C@](CN3C=CN=C3)(O2)C2=C(Cl)C=C(Cl)C=C2)C=C1
SLCO1B1	DB01110	solute carrier organic anion transporter family, member 1B1	approved; investigational	Miconazole	ClC1=CC(Cl)=C(COC(CN2C=CN=C2)C2=C(Cl)C=C(Cl)C=C2)C=C1
SLCO1B1	DB00515	solute carrier organic anion transporter family, member 1B1	approved	Cisplatin	N[Pt](N)(Cl)Cl
SLCO1B3	DB00390	solute carrier organic anion transporter family, member 1B3	approved	Digoxin	C[C@H]1O[C@H](C[C@H](O)[C@@H]1O)O[C@H]1[C@@H](O)C[C@H](O[C@H]2[C@@H](O)C[C@H](O[C@H]3CC[C@@]4(C)[C@H](CC[C@@H]5[C@@H]4C[C@@H](O)[C@]4(C)C(CC[C@]54O)C4=CC(=O)OC4)C3)O[C@@H]2C)O[C@@H]1C
SLCO1B3	DB00584	solute carrier organic anion transporter family, member 1B3	approved	Enalapril	CCOC(=O)[C@@H](CCC1=CC=CC=C1)N[C@@H](C)C(=O)N1CCC[C@H]1C(O)=O
SLCO1B3	DB00279	solute carrier organic anion transporter family, member 1B3	approved	Liothyronine	N[C@@H](CC1=CC(I)=C(OC2=CC(I)=C(O)C=C2)C(I)=C1)C(O)=O
SLCO1B3	DB00563	solute carrier organic anion transporter family, member 1B3	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
SLCO1B3	DB00275	solute carrier organic anion transporter family, member 1B3	approved; investigational	Olmesartan	CCCC1=NC(=C(N1CC1=CC=C(C=C1)C1=CC=CC=C1C1=NNN=N1)C(=O)OCC1=C(C)OC(=O)O1)C(C)(C)O
SLCO1B3	DB01092	solute carrier organic anion transporter family, member 1B3	approved	Ouabain	C[C@@H]1O[C@@H](O[C@H]2C[C@@H](O)[C@]3(CO)[C@H]4[C@H](O)C[C@]5(C)[C@H](CC[C@]5(O)[C@@H]4CC[C@]3(O)C2)C2=CC(=O)OC2)[C@H](O)[C@H](O)[C@H]1O
SLCO1B3	DB00966	solute carrier organic anion transporter family, member 1B3	approved; investigational	Telmisartan	CCCC1=NC2=C(C=C(C=C2C)C2=NC3=CC=CC=C3N2C)N1CC1=CC=C(C=C1)C1=CC=CC=C1C(O)=O
SLCO1B3	DB00177	solute carrier organic anion transporter family, member 1B3	approved; investigational	Valsartan	CCCCC(=O)N(CC1=CC=C(C=C1)C1=CC=CC=C1C1=NNN=N1)[C@@H](C(C)C)C(O)=O
SLCO1B3	DB00688	solute carrier organic anion transporter family, member 1B3	approved; investigational	Mycophenolate mofetil	COC1=C(C\C=C(/C)CCC(=O)OCCN2CCOCC2)C(O)=C2C(=O)OCC2=C1C
SLCO1B3	DB00877	solute carrier organic anion transporter family, member 1B3	approved; investigational	Sirolimus	CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1O
SLCO1B3	DB00864	solute carrier organic anion transporter family, member 1B3	approved; investigational	Tacrolimus	CO[C@@H]1C[C@@H](CC[C@H]1O)\C=C(/C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H]([C@H](C[C@H]2C)OC)[C@H](C[C@@H](C)C\C(C)=C\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]1C)OC
SLCO1B3	DB00199	solute carrier organic anion transporter family, member 1B3	approved	Erythromycin	CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O
SLCO1B3	DB01241	solute carrier organic anion transporter family, member 1B3	approved	Gemfibrozil	CC1=CC(OCCCC(C)(C)C(O)=O)=C(C)C=C1
SLCO1B3	DB00145	solute carrier organic anion transporter family, member 1B3	approved; nutraceutical	Glycine	NCC(O)=O
SLCO1B3	DB01095	solute carrier organic anion transporter family, member 1B3	approved	Fluvastatin	CC(C)N1C(\C=C\[C@H](O)C[C@H](O)CC(O)=O)=C(C2=CC=C(F)C=C2)C2=CC=CC=C12
SLCO1B3	DB01098	solute carrier organic anion transporter family, member 1B3	approved	Rosuvastatin	CC(C)C1=NC(=NC(C2=CC=C(F)C=C2)=C1\C=C\[C@H](O)C[C@@H](O)CC(O)=O)N(C)S(=O)(=O)C
SLCO1B3	DB01601	solute carrier organic anion transporter family, member 1B3	approved	Lopinavir	CC(C)[C@H](N1CCCNC1=O)C(=O)N[C@H](C[C@H](O)[C@H](CC1=CC=CC=C1)NC(=O)COC1=C(C)C=CC=C1C)CC1=CC=CC=C1
SLCO1B3	DB01229	solute carrier organic anion transporter family, member 1B3	approved	Paclitaxel	CC(=O)O[C@@H]1C2=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)C3=CC=CC=C3)[C@@H]3[C@@]4(CO[C@@H]4C[C@H](O)[C@@]3(C)C1=O)OC(C)=O)C2(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)C1=CC=CC=C1)C1=CC=CC=C1
SLCO1B3	DB00559	solute carrier organic anion transporter family, member 1B3	approved; investigational	Bosentan	COC1=CC=CC=C1OC1=C(NS(=O)(=O)C2=CC=C(C=C2)C(C)(C)C)N=C(N=C1OCCO)C1=NC=CC=N1
SLCO1B3	DB01045	solute carrier organic anion transporter family, member 1B3	approved	Rifampin	CO[C@H]1\C=C\O[C@@]2(C)OC3=C(C)C(O)=C4C(O)=C(NC(=O)\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@H](O)[C@H](C)[C@H](OC(C)=O)[C@@H]1C)C(\C=N\N1CCN(C)CC1)=C(O)C4=C3C2=O
SLCO1B3	DB00950	solute carrier organic anion transporter family, member 1B3	approved	Fexofenadine	CC(C)(C(O)=O)C1=CC=C(C=C1)C(O)CCCN1CCC(CC1)C(O)(C1=CC=CC=C1)C1=CC=CC=C1
SLCO1B3	DB00718	solute carrier organic anion transporter family, member 1B3	approved; investigational	Adefovir Dipivoxil	CC(C)(C)C(=O)OCOP(=O)(COCCN1C=NC2=C(N)N=CN=C12)OCOC(=O)C(C)(C)C
SLCO1B3	DB00501	solute carrier organic anion transporter family, member 1B3	approved	Cimetidine	C\N=C(\NCCSCC1=C(C)NC=N1)NC#N
SLCO1B3	DB01248	solute carrier organic anion transporter family, member 1B3	approved; investigational	Docetaxel	CC(=O)O[C@@]12CO[C@@H]1C[C@H](O)[C@]1(C)[C@@H]2[C@H](OC(=O)C2=CC=CC=C2)[C@]2(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C3=CC=CC=C3)C(C)=C([C@@H](O)C1=O)C2(C)C
SLCO1B3	DB00973	solute carrier organic anion transporter family, member 1B3	approved	Ezetimibe	O[C@@H](CC[C@@H]1[C@H](N(C1=O)C1=CC=C(F)C=C1)C1=CC=C(O)C=C1)C1=CC=C(F)C=C1
SLCO1B3	DB01024	solute carrier organic anion transporter family, member 1B3	approved	Mycophenolic acid	COC1=C(C\C=C(/C)CCC(O)=O)C(O)=C2C(=O)OCC2=C1C
SLCO1B3	DB00762	solute carrier organic anion transporter family, member 1B3	approved; investigational	Irinotecan	CCC1=C2CN3C(=CC4=C(COC(=O)[C@]4(O)CC)C3=O)C2=NC2=C1C=C(OC(=O)N1CCC(CC1)N1CCCCC1)C=C2
SMN2	DB00313	survival of motor neuron 2, centromeric	approved; investigational	Valproic Acid	CCCC(CCC)C(O)=O
SMOX	DB00127	spermine oxidase	approved; nutraceutical	Spermine	NCCCNCCCCNCCCN
SMPD1	DB01151	sphingomyelin phosphodiesterase 1, acid lysosomal	approved	Desipramine	CNCCCN1C2=CC=CC=C2CCC2=CC=CC=C12
SMPD1	DB00143	sphingomyelin phosphodiesterase 1, acid lysosomal	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
SMPD3	DB00144	sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)	approved; nutraceutical	Phosphatidylserine	CCCC(=O)O[C@H](COC(=O)CC)COP(O)(=O)OC[C@H](N)C(O)=O
SMPD3	DB00143	sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
SMPD4	DB00144	sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)	approved; nutraceutical	Phosphatidylserine	CCCC(=O)O[C@H](COC(=O)CC)COP(O)(=O)OC[C@H](N)C(O)=O
SMS	DB00127	spermine synthase	approved; nutraceutical	Spermine	NCCCNCCCCNCCCN
SMS	DB00134	spermine synthase	approved; nutraceutical	L-Methionine	CSCC[C@H](N)C(O)=O
SNAP25	DB00126	synaptosomal-associated protein, 25kDa	approved; nutraceutical	Vitamin C	OC[C@H](O)[C@H]1OC(=O)C(O)=C1O
SNAP25	DB00130	synaptosomal-associated protein, 25kDa	approved; nutraceutical; investigational	L-Glutamine	N[C@@H](CCC(N)=O)C(O)=O
SNAP25	DB00149	synaptosomal-associated protein, 25kDa	approved; nutraceutical	L-Leucine	CC(C)CC(N)C(O)=O
SNAP25	DB00122	synaptosomal-associated protein, 25kDa	approved; nutraceutical	Choline	C[N+](C)(C)CCO
SNAP25	DB00422	synaptosomal-associated protein, 25kDa	approved; investigational	Methylphenidate	COC(=O)C(C1CCCCN1)C1=CC=CC=C1
SNAP25	DB00988	synaptosomal-associated protein, 25kDa	approved	Dopamine	NCCC1=CC(O)=C(O)C=C1
SORD	DB00157	sorbitol dehydrogenase	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
SORD	DB01907	sorbitol dehydrogenase	experimental	Nicotinamide-Adenine-Dinucleotide	NC(=O)C1=CC=C[N+](=C1)[C@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@@H]1O
SORD	DB04478	sorbitol dehydrogenase	experimental	Cp-166572, 2-Hydroxymethyl-4-(4-N,N-Dimethylaminosulfonyl-1-Piperazino)-Pyrimidine	CN(C)S(=O)(=O)N1CCN(CC1)C1=CC=NC(CO)=N1
SPHK2	DB00143	sphingosine kinase 2	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
SPTLC1	DB00114	serine palmitoyltransferase, long chain base subunit 1	nutraceutical	Pyridoxal Phosphate	CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O
SPTLC1	DB00133	serine palmitoyltransferase, long chain base subunit 1	approved; nutraceutical	L-Serine	N[C@@H](CO)C(O)=O
SPTLC2	DB00114	serine palmitoyltransferase, long chain base subunit 2	nutraceutical	Pyridoxal Phosphate	CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O
SPTLC2	DB00133	serine palmitoyltransferase, long chain base subunit 2	approved; nutraceutical	L-Serine	N[C@@H](CO)C(O)=O
SRD5A1	DB00367	steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)	approved; investigational	Levonorgestrel	CC[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@H]34)[C@@H]1CC[C@@]2(O)C#C
SRD5A1	DB01126	steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)	approved; investigational	Dutasteride	C[C@]12CCC3[C@@H](CC[C@H]4NC(=O)C=C[C@]34C)[C@@H]1CC[C@@H]2C(=O)NC1=C(C=CC(=C1)C(F)(F)F)C(F)(F)F
SRD5A1	DB01216	steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)	approved	Finasteride	CC(C)(C)NC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4NC(=O)C=C[C@]4(C)[C@H]3CC[C@]12C
SRD5A2	DB00548	steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)	approved	Azelaic Acid	OC(=O)CCCCCCCC(O)=O
SRD5A2	DB01126	steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)	approved; investigational	Dutasteride	C[C@]12CCC3[C@@H](CC[C@H]4NC(=O)C=C[C@]34C)[C@@H]1CC[C@@H]2C(=O)NC1=C(C=CC(=C1)C(F)(F)F)C(F)(F)F
SRD5A2	DB01216	steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)	approved	Finasteride	CC(C)(C)NC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4NC(=O)C=C[C@]4(C)[C@H]3CC[C@]12C
SREBF1	DB00363	sterol regulatory element binding transcription factor 1	approved	Clozapine	CN1CCN(CC1)C1=NC2=CC(Cl)=CC=C2NC2=CC=CC=C12
SREBF1	DB00502	sterol regulatory element binding transcription factor 1	approved	Haloperidol	OC1(CCN(CCCC(=O)C2=CC=C(F)C=C2)CC1)C1=CC=C(Cl)C=C1
SREBF1	DB00755	sterol regulatory element binding transcription factor 1	approved; nutraceutical; investigational	Tretinoin	CC(C=CC1=C(C)CCCC1(C)C)=CC=CC(C)=CC(O)=O
SREBF1	DB00331	sterol regulatory element binding transcription factor 1	approved	Metformin	CN(C)C(=N)NC(N)=N
SREBF1	DB01076	sterol regulatory element binding transcription factor 1	approved	Atorvastatin	CC(C)C1=C(C(=O)NC2=CC=CC=C2)C(=C(N1CC[C@@H](O)C[C@@H](O)CC(O)=O)C1=CC=C(F)C=C1)C1=CC=CC=C1
SREBF1	DB01095	sterol regulatory element binding transcription factor 1	approved	Fluvastatin	CC(C)N1C(\C=C\[C@H](O)C[C@H](O)CC(O)=O)=C(C2=CC=C(F)C=C2)C2=CC=CC=C12
SREBF1	DB00227	sterol regulatory element binding transcription factor 1	approved; investigational	Lovastatin	CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12
SREBF1	DB00175	sterol regulatory element binding transcription factor 1	approved	Pravastatin	CC[C@H](C)C(=O)O[C@H]1C[C@H](O)C=C2C=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC(O)=O)[C@@H]12
SREBF1	DB01098	sterol regulatory element binding transcription factor 1	approved	Rosuvastatin	CC(C)C1=NC(=NC(C2=CC=C(F)C=C2)=C1\C=C\[C@H](O)C[C@@H](O)CC(O)=O)N(C)S(=O)(=O)C
SREBF1	DB00641	sterol regulatory element binding transcription factor 1	approved	Simvastatin	CCC(C)(C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CCC3C[C@@H](O)CC(=O)O3)[C@@H]12
SREBF2	DB00363	sterol regulatory element binding transcription factor 2	approved	Clozapine	CN1CCN(CC1)C1=NC2=CC(Cl)=CC=C2NC2=CC=CC=C12
SREBF2	DB00502	sterol regulatory element binding transcription factor 2	approved	Haloperidol	OC1(CCN(CCCC(=O)C2=CC=C(F)C=C2)CC1)C1=CC=C(Cl)C=C1
SRM	DB00134	spermidine synthase	approved; nutraceutical	L-Methionine	CSCC[C@H](N)C(O)=O
SRR	DB00114	serine racemase	nutraceutical	Pyridoxal Phosphate	CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O
SRR	DB00133	serine racemase	approved; nutraceutical	L-Serine	N[C@@H](CO)C(O)=O
ST6GAL1	DB00301	ST6 beta-galactosamide alpha-2,6-sialyltranferase 1	approved	Flucloxacillin	CC1=C(C(=O)N[C@H]2[C@H]3SC(C)(C)[C@@H](N3C2=O)C(O)=O)C(=NO1)C1=C(F)C=CC=C1Cl
STK11	DB00331	serine/threonine kinase 11	approved	Metformin	CN(C)C(=N)NC(N)=N
STS	DB01808	steroid sulfatase (microsomal), isozyme S	experimental	Thiarsahydroxy-Cysteine	N[C@@H](CS[AsH]O)C(O)=O
STS	DB03352	steroid sulfatase (microsomal), isozyme S	experimental	S-Arsonocysteine	N[C@@H](CS[As](O)(O)=O)C(O)=O
STS	DB04456	steroid sulfatase (microsomal), isozyme S	experimental	Trihydroxyarsenite(Iii)	O[As](O)O
STS	DB02763	steroid sulfatase (microsomal), isozyme S	experimental	5-Mercapto-2-Nitro-Benzoic Acid	OC(=O)C1=CC(S)=CC=C1[N+]([O-])=O
STS	DB03138	steroid sulfatase (microsomal), isozyme S	experimental	Perchlorate Ion	[O-][Cl](=O)(=O)=O
STX1A	DB00126	syntaxin 1A (brain)	approved; nutraceutical	Vitamin C	OC[C@H](O)[C@H]1OC(=O)C(O)=C1O
STX1A	DB00130	syntaxin 1A (brain)	approved; nutraceutical; investigational	L-Glutamine	N[C@@H](CCC(N)=O)C(O)=O
STX1A	DB00149	syntaxin 1A (brain)	approved; nutraceutical	L-Leucine	CC(C)CC(N)C(O)=O
STX1A	DB00122	syntaxin 1A (brain)	approved; nutraceutical	Choline	C[N+](C)(C)CCO
STX1A	DB00988	syntaxin 1A (brain)	approved	Dopamine	NCCC1=CC(O)=C(O)C=C1
STXBP1	DB00126	syntaxin binding protein 1	approved; nutraceutical	Vitamin C	OC[C@H](O)[C@H]1OC(=O)C(O)=C1O
STXBP1	DB00130	syntaxin binding protein 1	approved; nutraceutical; investigational	L-Glutamine	N[C@@H](CCC(N)=O)C(O)=O
STXBP1	DB00149	syntaxin binding protein 1	approved; nutraceutical	L-Leucine	CC(C)CC(N)C(O)=O
STXBP1	DB00122	syntaxin binding protein 1	approved; nutraceutical	Choline	C[N+](C)(C)CCO
STXBP1	DB00988	syntaxin binding protein 1	approved	Dopamine	NCCC1=CC(O)=C(O)C=C1
SUCLA2	DB00139	succinate-CoA ligase, ADP-forming, beta subunit	approved; nutraceutical	Succinic acid	OC(=O)CCC(O)=O
SUCLG1	DB00139	succinate-CoA ligase, alpha subunit	approved; nutraceutical	Succinic acid	OC(=O)CCC(O)=O
SUCLG2	DB00139	succinate-CoA ligase, GDP-forming, beta subunit	approved; nutraceutical	Succinic acid	OC(=O)CCC(O)=O
SULT1A1	DB01812	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1	experimental	Adenosine-3'-5'-Diphosphate	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](COP(O)(O)=O)[C@H](OP(O)(O)=O)[C@H]1O
SULT1A1	DB04417	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1	experimental	P-Nitrophenol	OC1=CC=C(C=C1)[N+]([O-])=O
SULT1A1	DB00818	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1	approved; investigational	Propofol	CC(C)C1=CC=CC(C(C)C)=C1O
SULT1A1	DB00350	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1	approved	Minoxidil	NC1=CC(=NC(N)=[N+]1[O-])N1CCCCC1
SULT1A1	DB00316	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1	approved	Acetaminophen	CC(=O)NC1=CC=C(O)C=C1
SULT1A1	DB00988	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1	approved	Dopamine	NCCC1=CC(O)=C(O)C=C1
SULT1A1	DB00655	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1	approved	Estrone	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CCC2=O
SULT1A1	DB03255	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1	experimental	Phenol	OC1=CC=CC=C1
SULT1A1	DB00286	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1	approved	Conjugated Estrogens	[Na+].C[C@]12CC[C@H]3[C@@H](CCC4=CC(OS([O-])(=O)=O)=CC=C34)[C@@H]1CCC2=O
SULT1A1	DB00675	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1	approved	Tamoxifen	CC\C(=C(/C1=CC=CC=C1)C1=CC=C(OCCN(C)C)C=C1)C1=CC=CC=C1
SULT1A1	DB00783	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1	approved; investigational	Estradiol	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CC[C@@H]2O
SULT1A1	DB01708	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1	nutraceutical	Dehydroepiandrosterone	C[C@]12CC[C@H]3[C@@H](CC=C4C[C@@H](O)CC[C@]34C)[C@@H]1CCC2=O
SULT1A1	DB00564	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1	approved; investigational	Carbamazepine	NC(=O)N1C2=CC=CC=C2C=CC2=CC=CC=C12
SULT1A1	DB00451	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1	approved	Levothyroxine	N[C@@H](CC1=CC(I)=C(OC2=CC(I)=C(O)C(I)=C2)C(I)=C1)C(O)=O
SULT1A2	DB01708	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2	nutraceutical	Dehydroepiandrosterone	C[C@]12CC[C@H]3[C@@H](CC=C4C[C@@H](O)CC[C@]34C)[C@@H]1CCC2=O
SULT1A2	DB00783	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2	approved; investigational	Estradiol	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CC[C@@H]2O
SULT1A2	DB00675	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2	approved	Tamoxifen	CC\C(=C(/C1=CC=CC=C1)C1=CC=C(OCCN(C)C)C=C1)C1=CC=CC=C1
SULT1A3	DB00316	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3	approved	Acetaminophen	CC(=O)NC1=CC=C(O)C=C1
SULT1A3	DB00988	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3	approved	Dopamine	NCCC1=CC(O)=C(O)C=C1
SULT1A3	DB00655	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3	approved	Estrone	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CCC2=O
SULT1A3	DB03255	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3	experimental	Phenol	OC1=CC=CC=C1
SULT1A3	DB00368	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3	approved	Norepinephrine	NC[C@H](O)C1=CC(O)=C(O)C=C1
SULT1A3	DB01708	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3	nutraceutical	Dehydroepiandrosterone	C[C@]12CC[C@H]3[C@@H](CC=C4C[C@@H](O)CC[C@]34C)[C@@H]1CCC2=O
SULT1A3	DB00783	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3	approved; investigational	Estradiol	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CC[C@@H]2O
SULT1A3	DB00675	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3	approved	Tamoxifen	CC\C(=C(/C1=CC=CC=C1)C1=CC=C(OCCN(C)C)C=C1)C1=CC=CC=C1
SULT1A4	DB00316	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4	approved	Acetaminophen	CC(=O)NC1=CC=C(O)C=C1
SULT1A4	DB00988	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4	approved	Dopamine	NCCC1=CC(O)=C(O)C=C1
SULT1A4	DB00655	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4	approved	Estrone	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CCC2=O
SULT1A4	DB03255	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4	experimental	Phenol	OC1=CC=CC=C1
SULT1A4	DB01708	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4	nutraceutical	Dehydroepiandrosterone	C[C@]12CC[C@H]3[C@@H](CC=C4C[C@@H](O)CC[C@]34C)[C@@H]1CCC2=O
SULT1A4	DB00783	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4	approved; investigational	Estradiol	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CC[C@@H]2O
SULT1A4	DB00675	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4	approved	Tamoxifen	CC\C(=C(/C1=CC=CC=C1)C1=CC=C(OCCN(C)C)C=C1)C1=CC=CC=C1
SULT1E1	DB01176	sulfotransferase family 1E, estrogen-preferring, member 1	approved	Cyclizine	CN1CCN(CC1)C(C1=CC=CC=C1)C1=CC=CC=C1
SULT1E1	DB01812	sulfotransferase family 1E, estrogen-preferring, member 1	experimental	Adenosine-3'-5'-Diphosphate	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](COP(O)(O)=O)[C@H](OP(O)(O)=O)[C@H]1O
SULT1E1	DB02902	sulfotransferase family 1E, estrogen-preferring, member 1	experimental	3'-Phosphate-Adenosine-5'-Phosphate Sulfate	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](CO[P@](O)(=O)OS(O)(=O)=O)[C@H](OP(O)(O)=O)[C@H]1O
SULT1E1	DB03346	sulfotransferase family 1E, estrogen-preferring, member 1	experimental	3,5,3',5'-Tetrachloro-Biphenyl-4,4'-Diol	OC1=C(Cl)C=C(C=C1Cl)C1=CC(Cl)=C(O)C(Cl)=C1
SULT1E1	DB00988	sulfotransferase family 1E, estrogen-preferring, member 1	approved	Dopamine	NCCC1=CC(O)=C(O)C=C1
SULT1E1	DB00655	sulfotransferase family 1E, estrogen-preferring, member 1	approved	Estrone	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CCC2=O
SULT1E1	DB03255	sulfotransferase family 1E, estrogen-preferring, member 1	experimental	Phenol	OC1=CC=CC=C1
SULT1E1	DB00286	sulfotransferase family 1E, estrogen-preferring, member 1	approved	Conjugated Estrogens	[Na+].C[C@]12CC[C@H]3[C@@H](CCC4=CC(OS([O-])(=O)=O)=CC=C34)[C@@H]1CCC2=O
SULT1E1	DB00783	sulfotransferase family 1E, estrogen-preferring, member 1	approved; investigational	Estradiol	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CC[C@@H]2O
SULT1E1	DB00481	sulfotransferase family 1E, estrogen-preferring, member 1	approved; investigational	Raloxifene	OC1=CC=C(C=C1)C1=C(C(=O)C2=CC=C(OCCN3CCCCC3)C=C2)C2=C(S1)C=C(O)C=C2
SULT1E1	DB01708	sulfotransferase family 1E, estrogen-preferring, member 1	nutraceutical	Dehydroepiandrosterone	C[C@]12CC[C@H]3[C@@H](CC=C4C[C@@H](O)CC[C@]34C)[C@@H]1CCC2=O
SULT1E1	DB00675	sulfotransferase family 1E, estrogen-preferring, member 1	approved	Tamoxifen	CC\C(=C(/C1=CC=CC=C1)C1=CC=C(OCCN(C)C)C=C1)C1=CC=CC=C1
SULT2A1	DB01708	sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1	nutraceutical	Dehydroepiandrosterone	C[C@]12CC[C@H]3[C@@H](CC=C4C[C@@H](O)CC[C@]34C)[C@@H]1CCC2=O
SULT2A1	DB01812	sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1	experimental	Adenosine-3'-5'-Diphosphate	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](COP(O)(O)=O)[C@H](OP(O)(O)=O)[C@H]1O
SULT2A1	DB02854	sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1	experimental	Aetiocholanolone	C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@H](O)CC[C@]34C)[C@@H]1CCC2=O
SULT2A1	DB04445	sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1	experimental	Mercury Diiodide	I[Hg]I
SULT2A1	DB00988	sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1	approved	Dopamine	NCCC1=CC(O)=C(O)C=C1
SULT2A1	DB00655	sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1	approved	Estrone	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CCC2=O
SULT2A1	DB03255	sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1	experimental	Phenol	OC1=CC=CC=C1
SULT2A1	DB00783	sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1	approved; investigational	Estradiol	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CC[C@@H]2O
SULT2A1	DB00675	sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1	approved	Tamoxifen	CC\C(=C(/C1=CC=CC=C1)C1=CC=C(OCCN(C)C)C=C1)C1=CC=CC=C1
SULT2B1	DB01708	sulfotransferase family, cytosolic, 2B, member 1	nutraceutical	Dehydroepiandrosterone	C[C@]12CC[C@H]3[C@@H](CC=C4C[C@@H](O)CC[C@]34C)[C@@H]1CCC2=O
SULT2B1	DB01812	sulfotransferase family, cytosolic, 2B, member 1	experimental	Adenosine-3'-5'-Diphosphate	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](COP(O)(O)=O)[C@H](OP(O)(O)=O)[C@H]1O
SULT2B1	DB02789	sulfotransferase family, cytosolic, 2B, member 1	experimental	Pregnenolone	CC(=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
SULT2B1	DB03309	sulfotransferase family, cytosolic, 2B, member 1	experimental	N-Cyclohexyltaurine	OS(=O)(=O)CCNC1CCCCC1
SULT2B1	DB00988	sulfotransferase family, cytosolic, 2B, member 1	approved	Dopamine	NCCC1=CC(O)=C(O)C=C1
SULT2B1	DB00655	sulfotransferase family, cytosolic, 2B, member 1	approved	Estrone	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CCC2=O
SULT2B1	DB03255	sulfotransferase family, cytosolic, 2B, member 1	experimental	Phenol	OC1=CC=CC=C1
SULT2B1	DB00783	sulfotransferase family, cytosolic, 2B, member 1	approved; investigational	Estradiol	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CC[C@@H]2O
SULT2B1	DB00675	sulfotransferase family, cytosolic, 2B, member 1	approved	Tamoxifen	CC\C(=C(/C1=CC=CC=C1)C1=CC=C(OCCN(C)C)C=C1)C1=CC=CC=C1
SUOX	DB03014	sulfite oxidase	experimental	Heme	CC1=C(CCC(O)=O)C2=CC3=[N+]4C(=CC5=C(C=C)C(C)=C6C=C7C(C=C)=C(C)C8=[N+]7[Fe@]4(N2C1=C8)N56)C(C)=C3CCC(O)=O
SUOX	DB03983	sulfite oxidase	experimental	(Molybdopterin-S,S)-Dioxo-Thio-Molybdenum(V)	NC1=NC2=C(N[C@@H]3[C@H](N2)O[C@@H](COP(O)(O)=O)C2=C3S[Mo](S)(=O)(=O)S2)C(=O)N1
SYNJ2	DB00171	synaptojanin 2	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
SYT5	DB00121	synaptotagmin V	approved; nutraceutical	Biotin	OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12
TAT	DB00114	tyrosine aminotransferase	nutraceutical	Pyridoxal Phosphate	CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O
TAT	DB00120	tyrosine aminotransferase	approved; nutraceutical	L-Phenylalanine	N[C@@H](CC1=CC=CC=C1)C(O)=O
TAT	DB00135	tyrosine aminotransferase	approved; nutraceutical	L-Tyrosine	N[C@@H](CC1=CC=C(O)C=C1)C(O)=O
TAT	DB00142	tyrosine aminotransferase	approved; nutraceutical	L-Glutamic Acid	N[C@@H](CCC(O)=O)C(O)=O
TAT	DB04083	tyrosine aminotransferase	experimental	N'-Pyridoxyl-Lysine-5'-Monophosphate	CC1=NC=C(COP(O)(O)=O)C(CNCCCC[C@@H](N)C(O)=O)=C1O
TAT	DB00143	tyrosine aminotransferase	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
TAT	DB00360	tyrosine aminotransferase	approved; investigational	Tetrahydrobiopterin	CC(O)C(O)C1CNC2=C(N1)C(=O)N=C(N)N2
TAT	DB01026	tyrosine aminotransferase	approved; investigational	Ketoconazole	CC(=O)N1CCN(CC1)C1=CC=C(OC[C@@H]2CO[C@](CN3C=CN=C3)(O2)C2=C(Cl)C=C(Cl)C=C2)C=C1
TAT	DB01110	tyrosine aminotransferase	approved; investigational	Miconazole	ClC1=CC(Cl)=C(COC(CN2C=CN=C2)C2=C(Cl)C=C(Cl)C=C2)C=C1
TBXAS1	DB01207	thromboxane A synthase 1 (platelet)	approved	Ridogrel	OC(=O)CCCCO\N=C(\C1=CN=CC=C1)C1=CC(=CC=C1)C(F)(F)F
TBXAS1	DB03052	thromboxane A synthase 1 (platelet)	experimental	Dazoxiben	OC(=O)C1=CC=C(OCCN2C=CN=C2)C=C1
TBXAS1	DB00564	thromboxane A synthase 1 (platelet)	approved; investigational	Carbamazepine	NC(=O)N1C2=CC=CC=C2C=CC2=CC=CC=C12
TBXAS1	DB00252	thromboxane A synthase 1 (platelet)	approved	Phenytoin	O=C1NC(=O)C(N1)(C1=CC=CC=C1)C1=CC=CC=C1
TBXAS1	DB00945	thromboxane A synthase 1 (platelet)	approved	Acetylsalicylic acid	CC(=O)OC1=CC=CC=C1C(O)=O
TBXAS1	DB00917	thromboxane A synthase 1 (platelet)	approved	Dinoprostone	CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O
TBXAS1	DB01240	thromboxane A synthase 1 (platelet)	approved	Epoprostenol	CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)C[C@@H]2OC(C[C@H]12)=CCCCC(O)=O
TBXAS1	DB00184	thromboxane A synthase 1 (platelet)	approved	Nicotine	CN1CCCC1C1=CN=CC=C1
TBXAS1	DB00482	thromboxane A synthase 1 (platelet)	approved; investigational	Celecoxib	CC1=CC=C(C=C1)C1=CC(=NN1C1=CC=C(C=C1)S(N)(=O)=O)C(F)(F)F
TDO2	DB00130	tryptophan 2,3-dioxygenase	approved; nutraceutical; investigational	L-Glutamine	N[C@@H](CCC(N)=O)C(O)=O
TDO2	DB00160	tryptophan 2,3-dioxygenase	approved; nutraceutical	L-Alanine	C[C@H](N)C(O)=O
TDO2	DB00150	tryptophan 2,3-dioxygenase	approved; nutraceutical	L-Tryptophan	N[C@@H](CC1=CNC2=CC=CC=C12)C(O)=O
TH	DB00120	tyrosine hydroxylase	approved; nutraceutical	L-Phenylalanine	N[C@@H](CC1=CC=CC=C1)C(O)=O
TH	DB00135	tyrosine hydroxylase	approved; nutraceutical	L-Tyrosine	N[C@@H](CC1=CC=C(O)C=C1)C(O)=O
TH	DB00360	tyrosine hydroxylase	approved; investigational	Tetrahydrobiopterin	CC(O)C(O)C1CNC2=C(N1)C(=O)N=C(N)N2
TH	DB00765	tyrosine hydroxylase	approved	Metyrosine	C[C@](N)(CC1=CC=C(O)C=C1)C(O)=O
TH	DB03552	tyrosine hydroxylase	experimental	Meta-Tyrosine	N[C@@H](CC1=CC=CC(O)=C1)C(O)=O
TH	DB04400	tyrosine hydroxylase	experimental	7,8-Dihydrobiopterin	C[C@@H](O)[C@@H](O)C1=NC2=C(NC1)N=C(N)NC2=O
TH	DB01394	tyrosine hydroxylase	approved	Colchicine	COC1=C(OC)C(OC)=C2C(CC[C@H](NC(C)=O)C3=CC(=O)C(OC)=CC=C23)=C1
TH	DB00988	tyrosine hydroxylase	approved	Dopamine	NCCC1=CC(O)=C(O)C=C1
TH	DB00864	tyrosine hydroxylase	approved; investigational	Tacrolimus	CO[C@@H]1C[C@@H](CC[C@H]1O)\C=C(/C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H]([C@H](C[C@H]2C)OC)[C@H](C[C@@H](C)C\C(C)=C\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]1C)OC
TH	DB01235	tyrosine hydroxylase	approved	Levodopa	N[C@@H](CC1=CC(O)=C(O)C=C1)C(O)=O
TH	DB00368	tyrosine hydroxylase	approved	Norepinephrine	NC[C@H](O)C1=CC(O)=C(O)C=C1
TK1	DB01692	thymidine kinase 1, soluble	experimental	Dithioerythritol	O[C@H](CS)[C@H](O)CS
TK1	DB02452	thymidine kinase 1, soluble	experimental	Thymidine-5'-Triphosphate	CC1=CN([C@H]2C[C@@H](O)[C@H](CO[P@@](O)(=O)O[P@@](O)(=O)OP(O)(O)=O)O2)C(=O)NC1=O
TK1	DB01101	thymidine kinase 1, soluble	approved; investigational	Capecitabine	CCCCCOC(=O)NC1=NC(=O)N(C=C1F)[C@@H]1O[C@H](C)[C@@H](O)[C@H]1O
TK1	DB00544	thymidine kinase 1, soluble	approved	Fluorouracil	FC1=CNC(=O)NC1=O
TK1	DB02745	thymidine kinase 1, soluble	experimental	Uridine	OC[C@@H]1O[C@H]([C@H](O)[C@H]1O)N1C=CC(=O)NC1=O
TK1	DB00495	thymidine kinase 1, soluble	approved	Zidovudine	CC1=CN([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2)C(=O)NC1=O
TK1	DB01033	thymidine kinase 1, soluble	approved	Mercaptopurine	S=C1N=CNC2=C1NC=N2
TK1	DB00563	thymidine kinase 1, soluble	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
TK1	DB01050	thymidine kinase 1, soluble	approved	Ibuprofen	CC(C)CC1=CC=C(C=C1)C(C)C(O)=O
TKTL1	DB02078	transketolase-like 1	experimental	1-Methoxy-2-[2-(2-Methoxy-Ethoxy]-Ethane	COCCOCCOCCOC
TMLHE	DB00126	trimethyllysine hydroxylase, epsilon	approved; nutraceutical	Vitamin C	OC[C@H](O)[C@H]1OC(=O)C(O)=C1O
TMLHE	DB00139	trimethyllysine hydroxylase, epsilon	approved; nutraceutical	Succinic acid	OC(=O)CCC(O)=O
TMLHE	DB00145	trimethyllysine hydroxylase, epsilon	approved; nutraceutical	Glycine	NCC(O)=O
TPH1	DB00360	tryptophan hydroxylase 1	approved; investigational	Tetrahydrobiopterin	CC(O)C(O)C1CNC2=C(N1)C(=O)N=C(N)N2
TPH1	DB03271	tryptophan hydroxylase 1	experimental	7,8-Dihydro-L-Biopterin	C[C@@H](O)[C@@H](O)C1=NC2=C(NC1)N=C(N)NC2=O
TPH1	DB00715	tryptophan hydroxylase 1	approved; investigational	Paroxetine	FC1=CC=C(C=C1)[C@@H]1CCNC[C@H]1COC1=CC2=C(OCO2)C=C1
TPH1	DB00176	tryptophan hydroxylase 1	approved; investigational	Fluvoxamine	COCCCCC(=NOCCN)C1=CC=C(C=C1)C(F)(F)F
TPH2	DB00215	tryptophan hydroxylase 2	approved	Citalopram	CN(C)CCCC1(OCC2=C1C=CC(=C2)C#N)C1=CC=C(F)C=C1
TPH2	DB00370	tryptophan hydroxylase 2	approved	Mirtazapine	CN1CCN2C(C1)C1=CC=CC=C1CC1=C2N=CC=C1
TPH2	DB00285	tryptophan hydroxylase 2	approved	Venlafaxine	COC1=CC=C(C=C1)C(CN(C)C)C1(O)CCCCC1
TPH2	DB00472	tryptophan hydroxylase 2	approved	Fluoxetine	CNCCC(OC1=CC=C(C=C1)C(F)(F)F)C1=CC=CC=C1
TPI1	DB01709	triosephosphate isomerase 1	experimental	2-Phosphoglyceric Acid	OC[C@@H](OP(O)(O)=O)C(O)=O
TPI1	DB01779	triosephosphate isomerase 1	experimental	Glycerol-2-Phosphate	OCC(CO)OP(O)(O)=O
TPI1	DB02515	triosephosphate isomerase 1	experimental	3-Phosphoglycerol	OC[C@@H](O)COP(O)(O)=O
TPI1	DB02726	triosephosphate isomerase 1	experimental	2-Phosphoglycolic Acid	OC(=O)COP(O)(O)=O
TPI1	DB02951	triosephosphate isomerase 1	experimental	3-Hydroxypyruvic Acid	OCC(=O)C(O)=O
TPI1	DB04510	triosephosphate isomerase 1	experimental	3-Phosphoglyceric Acid	O[C@@H](COP(O)(O)=O)C(O)=O
TPI1	DB01695	triosephosphate isomerase 1	experimental	N-Hydroxy-4-Phosphono-Butanamide	ONC(=O)CCCP([O-])([O-])=O
TPI1	DB03026	triosephosphate isomerase 1	experimental	Phosphoglycolohydroxamic Acid	ONC(=O)COP(O)(O)=O
TPI1	DB03132	triosephosphate isomerase 1	experimental	3-(2-Benzothiazolylthio)-1-Propanesulfonic Acid	OS(=O)(=O)CCCSC1=NC2=C(S1)C=CC=C2
TPI1	DB03135	triosephosphate isomerase 1	experimental	[2(Formyl-Hydroxy-Amino)-Ethyl]-Phosphonic Acid	ON(CCP(O)(O)=O)C=O
TPI1	DB03314	triosephosphate isomerase 1	experimental	Fluorotryptophane	N[C@@H](CC1=CNC2=C1C=C(F)C=C2)C(O)=O
TPI1	DB03379	triosephosphate isomerase 1	experimental	2-Carboxyethylphosphonic Acid	OC(=O)CCP(O)(O)=O
TPI1	DB03900	triosephosphate isomerase 1	experimental	2-Methyl-2-Propanol	CC(C)(C)O
TPI1	DB04326	triosephosphate isomerase 1	experimental	1,3-Dihydroxyacetonephosphate	OCC(=O)COP(O)(O)=O
TPI1	DB04447	triosephosphate isomerase 1	experimental	1,4-Dithiothreitol	O[C@H](CS)[C@H](O)CS
TPI1	DB07387	triosephosphate isomerase 1	experimental	3-(BUTYLSULPHONYL)-PROPANOIC ACID	CCCCS(=O)(=O)CCC(O)=O
TPI1	DB00121	triosephosphate isomerase 1	approved; nutraceutical	Biotin	OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12
TPK1	DB00152	thiamin pyrophosphokinase 1	approved; nutraceutical	Thiamine	CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N
TPK1	DB04768	thiamin pyrophosphokinase 1	experimental	Pyrithiamine Pyrophosphate	CC1=NC=C(C[N+]2=CC=CC(CCO[P@](O)(=O)OP(O)(O)=O)=C2C)C(N)=N1
TPMT	DB01250	thiopurine S-methyltransferase	approved	Olsalazine	OC(=O)C1=CC(=CC=C1O)\N=N\C1=CC=C(O)C(=C1)C(O)=O
TPMT	DB01234	thiopurine S-methyltransferase	approved; investigational	Dexamethasone	C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
TPMT	DB00650	thiopurine S-methyltransferase	approved	Leucovorin	NC1=NC(=O)C2=C(NCC(CNC3=CC=C(C=C3)C(=O)N[C@H](CCC(O)=O)C(O)=O)N2C=O)N1
TPMT	DB01248	thiopurine S-methyltransferase	approved; investigational	Docetaxel	CC(=O)O[C@@]12CO[C@@H]1C[C@H](O)[C@]1(C)[C@@H]2[C@H](OC(=O)C2=CC=CC=C2)[C@]2(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C3=CC=CC=C3)C(C)=C([C@@H](O)C1=O)C2(C)C
TPMT	DB00640	thiopurine S-methyltransferase	approved; investigational	Adenosine	NC1=C2N=CN([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)C2=NC=N1
TPMT	DB00134	thiopurine S-methyltransferase	approved; nutraceutical	L-Methionine	CSCC[C@H](N)C(O)=O
TPMT	DB01327	thiopurine S-methyltransferase	approved	Cefazolin	CC1=NN=C(SCC2=C(N3C(SC2)[C@H](NC(=O)CN2C=NN=N2)C3=O)C(O)=O)S1
TPMT	DB00544	thiopurine S-methyltransferase	approved	Fluorouracil	FC1=CNC(=O)NC1=O
TPMT	DB00762	thiopurine S-methyltransferase	approved; investigational	Irinotecan	CCC1=C2CN3C(=CC4=C(COC(=O)[C@]4(O)CC)C3=O)C2=NC2=C1C=C(OC(=O)N1CCC(CC1)N1CCCCC1)C=C2
TPMT	DB00987	thiopurine S-methyltransferase	approved; investigational	Cytarabine	NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O
TPMT	DB00694	thiopurine S-methyltransferase	approved	Daunorubicin	COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3O[C@H]3C[C@H](N)[C@H](O)[C@H](C)O3)C(C)=O)C(O)=C1C2=O
TPMT	DB00773	thiopurine S-methyltransferase	approved	Etoposide	COC1=CC(=CC(OC)=C1O)[C@H]1[C@@H]2[C@H](COC2=O)[C@H](O[C@@H]2O[C@@H]3CO[C@@H](C)O[C@H]3[C@H](O)[C@H]2O)C2=CC3=C(OCO3)C=C12
TPMT	DB01033	thiopurine S-methyltransferase	approved	Mercaptopurine	S=C1N=CNC2=C1NC=N2
TPMT	DB00563	thiopurine S-methyltransferase	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
TPMT	DB00635	thiopurine S-methyltransferase	approved	Prednisone	C[C@]12CC(=O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
TPMT	DB00541	thiopurine S-methyltransferase	approved; investigational	Vincristine	CC[C@]1(O)C[C@H]2CN(C1)CCC1=C(NC3=CC=CC=C13)[C@@](C2)(C(=O)OC)C1=C(OC)C=C2N(C=O)[C@@H]3[C@]4(CCN5CC=C[C@](CC)([C@@H]45)[C@@H](OC(C)=O)[C@]3(O)C(=O)OC)C2=C1
TPMT	DB00352	thiopurine S-methyltransferase	approved	Thioguanine	NC1=NC(=S)C2=C(N1)N=CN2
TPMT	DB00993	thiopurine S-methyltransferase	approved	Azathioprine	CN1C=NC(=C1SC1=NC=NC2=C1NC=N2)[N+]([O-])=O
TPMT	DB01454	thiopurine S-methyltransferase	illicit; experimental	3,4-Methylenedioxymethamphetamine	CNC(C)CC1=CC2=C(OCO2)C=C1
TPMT	DB00668	thiopurine S-methyltransferase	approved	Epinephrine	CNC[C@H](O)C1=CC(O)=C(O)C=C1
TPMT	DB00795	thiopurine S-methyltransferase	approved	Sulfasalazine	OC(=O)C1=CC(=CC=C1O)\N=N\C1=CC=C(C=C1)S(=O)(=O)NC1=NC=CC=C1
TPMT	DB00515	thiopurine S-methyltransferase	approved	Cisplatin	N[Pt](N)(Cl)Cl
TPO	DB00389	thyroid peroxidase	approved	Carbimazole	CCOC(=O)N1C=CN(C)C1=S
TPO	DB00509	thyroid peroxidase	approved	Dextrothyroxine	NC(CC1=CC(I)=C(OC2=CC(I)=C(O)C(I)=C2)C(I)=C1)C(O)=O
TPO	DB00550	thyroid peroxidase	approved	Propylthiouracil	CCCC1=CC(=O)NC(=S)N1
TPO	DB00763	thyroid peroxidase	approved	Methimazole	CN1C=CNC1=S
TPR	DB02240	translocated promoter region, nuclear basket protein	experimental	N-{(1s)-4-[Bis(2-Chloroethyl)Amino]-1-Methylbutyl}-N-(6-Chloro-2-Methoxy-9-Acridinyl)Amine	ClCCN(CCCl)CCC[C@H](C)\N=C1/C2=CC=C(Cl)C=C2NC2=CC=C(OC)C=C12
TPR	DB03147	translocated promoter region, nuclear basket protein	experimental	Flavin-Adenine Dinucleotide	CC1=CC2=C(C=C1C)N(C[C@H](O)[C@H](O)[C@H](O)CO[P@](O)(=O)O[P@@](O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC3=C1N=CN=C3N)C1=NC(=O)NC(=O)C1=N2
TPR	DB03470	translocated promoter region, nuclear basket protein	experimental	Trypanothione	N[C@@H](CCC(=O)N[C@H](CS)C(=O)NCC(=O)NCCCCNCCCNC(=O)CNC(=O)[C@H](CS)NC(=O)CC[C@@H](N)C(O)=O)C(O)=O
TPR	DB04299	translocated promoter region, nuclear basket protein	experimental	Maleic Acid	OC(=O)\C=C\C(O)=O
TRAM1	DB08081	translocation associated membrane protein 1	experimental	3-OXO-OCTANOIC ACID (2-OXO-TETRAHYDRO-FURAN-3-YL)-AMIDE	CCCCCC(=O)CC(=O)N[C@H]1CCOC1=O
TRDMT1	DB00738	tRNA aspartic acid methyltransferase 1	approved	Pentamidine	NC(=N)C1=CC=C(OCCCCCOC2=CC=C(C=C2)C(N)=N)C=C1
TRDMT1	DB01752	tRNA aspartic acid methyltransferase 1	experimental	S-Adenosyl-L-Homocysteine	N[C@@H](CCSC[C@@H]1O[C@H]([C@H](O)[C@H]1O)N1C=NC2=C1N=CN=C2N)C(O)=O
TRDMT1	DB04077	tRNA aspartic acid methyltransferase 1	experimental	Glycerol	OCC(O)CO
TREH	DB04465	trehalase (brush-border membrane glycoprotein)	experimental	Lactose	OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O
TSHB	DB00451	thyroid stimulating hormone, beta	approved	Levothyroxine	N[C@@H](CC1=CC(I)=C(OC2=CC(I)=C(O)C(I)=C2)C(I)=C1)C(O)=O
TST	DB04053	thiosulfate sulfurtransferase (rhodanese)	experimental	Hypophosphite	[O-]P=O
TST	DB02761	thiosulfate sulfurtransferase (rhodanese)	experimental	S-Mercaptocysteine	N[C@@H](CSS)C(O)=O
TSTA3	DB00157	tissue specific transplantation antigen P35B	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
TSTA3	DB02897	tissue specific transplantation antigen P35B	experimental	Acetylphosphate	CC(=O)OP(O)(O)=O
TSTA3	DB03461	tissue specific transplantation antigen P35B	experimental	2'-Monophosphoadenosine 5'-Diphosphoribose	NC(=O)C1=CC=C[N+](=C1)[C@@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@@H]2O[C@H]([C@H](OP(O)(O)=O)[C@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@H]1O
TUBA1A	DB00518	tubulin, alpha 1a	approved	Albendazole	CCCSC1=CC2=C(C=C1)N=C(NC(=O)OC)N2
TUBA1A	DB00570	tubulin, alpha 1a	approved	Vinblastine	CC[C@]1(O)C[C@H]2CN(C1)CCC1=C(NC3=CC=CC=C13)[C@@](C2)(C(=O)OC)C1=CC2=C(C=C1OC)N(C)[C@@H]1[C@]22CCN3CC=C[C@](CC)([C@@H]23)[C@@H](OC(C)=O)[C@]1(O)C(=O)OC
TUBA1A	DB00643	tubulin, alpha 1a	approved	Mebendazole	COC(=O)NC1=NC2=C(N1)C=C(C=C2)C(=O)C1=CC=CC=C1
TUBA1A	DB01873	tubulin, alpha 1a	experimental; investigational	Epothilone D	C[C@H]1CCC\C(C)=C/C[C@@H](OC(=O)C[C@@H](O)C(C)(C)C(=O)[C@@H](C)[C@@H]1O)C(\C)=C\C1=CSC(C)=N1
TUBA1A	DB03010	tubulin, alpha 1a	experimental; investigational	Epothilone B	C[C@H]1CCC[C@]2(C)O[C@H]2C[C@H](OC(=O)C[C@@H](O)C(C)(C)C(=O)[C@@H](C)[C@@H]1O)C(\C)=C\C1=CSC(C)=N1
TUBA1A	DB07574	tubulin, alpha 1a	experimental	2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE	COC1=CC2=C(C(OC)=C1OC)C1=CC=C(OC)C(=O)C=C1[C@H](CC2)NC(=O)CS
TUBA1B	DB01873	tubulin, alpha 1b	experimental; investigational	Epothilone D	C[C@H]1CCC\C(C)=C/C[C@@H](OC(=O)C[C@@H](O)C(C)(C)C(=O)[C@@H](C)[C@@H]1O)C(\C)=C\C1=CSC(C)=N1
TUBA1B	DB03010	tubulin, alpha 1b	experimental; investigational	Epothilone B	C[C@H]1CCC[C@]2(C)O[C@H]2C[C@H](OC(=O)C[C@@H](O)C(C)(C)C(=O)[C@@H](C)[C@@H]1O)C(\C)=C\C1=CSC(C)=N1
TUBA1B	DB07574	tubulin, alpha 1b	experimental	2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE	COC1=CC2=C(C(OC)=C1OC)C1=CC=C(OC)C(=O)C=C1[C@H](CC2)NC(=O)CS
TUBA1C	DB01873	tubulin, alpha 1c	experimental; investigational	Epothilone D	C[C@H]1CCC\C(C)=C/C[C@@H](OC(=O)C[C@@H](O)C(C)(C)C(=O)[C@@H](C)[C@@H]1O)C(\C)=C\C1=CSC(C)=N1
TUBA1C	DB03010	tubulin, alpha 1c	experimental; investigational	Epothilone B	C[C@H]1CCC[C@]2(C)O[C@H]2C[C@H](OC(=O)C[C@@H](O)C(C)(C)C(=O)[C@@H](C)[C@@H]1O)C(\C)=C\C1=CSC(C)=N1
TUBA1C	DB07574	tubulin, alpha 1c	experimental	2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE	COC1=CC2=C(C(OC)=C1OC)C1=CC=C(OC)C(=O)C=C1[C@H](CC2)NC(=O)CS
TUBA3C	DB01873	tubulin, alpha 3c	experimental; investigational	Epothilone D	C[C@H]1CCC\C(C)=C/C[C@@H](OC(=O)C[C@@H](O)C(C)(C)C(=O)[C@@H](C)[C@@H]1O)C(\C)=C\C1=CSC(C)=N1
TUBA3C	DB03010	tubulin, alpha 3c	experimental; investigational	Epothilone B	C[C@H]1CCC[C@]2(C)O[C@H]2C[C@H](OC(=O)C[C@@H](O)C(C)(C)C(=O)[C@@H](C)[C@@H]1O)C(\C)=C\C1=CSC(C)=N1
TUBA4A	DB00541	tubulin, alpha 4a	approved; investigational	Vincristine	CC[C@]1(O)C[C@H]2CN(C1)CCC1=C(NC3=CC=CC=C13)[C@@](C2)(C(=O)OC)C1=C(OC)C=C2N(C=O)[C@@H]3[C@]4(CCN5CC=C[C@](CC)([C@@H]45)[C@@H](OC(C)=O)[C@]3(O)C(=O)OC)C2=C1
TUBA4A	DB01179	tubulin, alpha 4a	approved	Podofilox	COC1=CC(=CC(OC)=C1OC)[C@H]1[C@@H]2[C@H](COC2=O)[C@@H](O)C2=CC3=C(OCO3)C=C12
TUBA4A	DB01873	tubulin, alpha 4a	experimental; investigational	Epothilone D	C[C@H]1CCC\C(C)=C/C[C@@H](OC(=O)C[C@@H](O)C(C)(C)C(=O)[C@@H](C)[C@@H]1O)C(\C)=C\C1=CSC(C)=N1
TUBA4A	DB03010	tubulin, alpha 4a	experimental; investigational	Epothilone B	C[C@H]1CCC[C@]2(C)O[C@H]2C[C@H](OC(=O)C[C@@H](O)C(C)(C)C(=O)[C@@H](C)[C@@H]1O)C(\C)=C\C1=CSC(C)=N1
TUBA4A	DB06772	tubulin, alpha 4a	approved	Cabazitaxel	CO[C@H]1C[C@H]2OC[C@@]2(OC(C)=O)[C@H]2[C@H](OC(=O)C3=CC=CC=C3)[C@]3(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C4=CC=CC=C4)C(C)=C([C@@H](OC)C(=O)[C@]12C)C3(C)C
TUBA4A	DB01033	tubulin, alpha 4a	approved	Mercaptopurine	S=C1N=CNC2=C1NC=N2
TUBA4A	DB00563	tubulin, alpha 4a	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
TUBB1	DB00309	tubulin, beta 1 class VI	approved	Vindesine	CC[C@]1(O)C[C@H]2CN(C1)CCC1=C(NC3=CC=CC=C13)[C@@](C2)(C(=O)OC)C1=C(OC)C=C2N(C)[C@@H]3[C@]4(CCN5CC=C[C@](CC)([C@@H]45)[C@@H](O)[C@]3(O)C(N)=O)C2=C1
TUBB1	DB01229	tubulin, beta 1 class VI	approved	Paclitaxel	CC(=O)O[C@@H]1C2=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)C3=CC=CC=C3)[C@@H]3[C@@]4(CO[C@@H]4C[C@H](O)[C@@]3(C)C1=O)OC(C)=O)C2(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)C1=CC=CC=C1)C1=CC=CC=C1
TUBB1	DB01248	tubulin, beta 1 class VI	approved; investigational	Docetaxel	CC(=O)O[C@@]12CO[C@@H]1C[C@H](O)[C@]1(C)[C@@H]2[C@H](OC(=O)C2=CC=CC=C2)[C@]2(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C3=CC=CC=C3)C(C)=C([C@@H](O)C1=O)C2(C)C
TUBB1	DB01394	tubulin, beta 1 class VI	approved	Colchicine	COC1=C(OC)C(OC)=C2C(CC[C@H](NC(C)=O)C3=CC(=O)C(OC)=CC=C23)=C1
TUBB1	DB01873	tubulin, beta 1 class VI	experimental; investigational	Epothilone D	C[C@H]1CCC\C(C)=C/C[C@@H](OC(=O)C[C@@H](O)C(C)(C)C(=O)[C@@H](C)[C@@H]1O)C(\C)=C\C1=CSC(C)=N1
TUBB1	DB03010	tubulin, beta 1 class VI	experimental; investigational	Epothilone B	C[C@H]1CCC[C@]2(C)O[C@H]2C[C@H](OC(=O)C[C@@H](O)C(C)(C)C(=O)[C@@H](C)[C@@H]1O)C(\C)=C\C1=CSC(C)=N1
TUBB1	DB06772	tubulin, beta 1 class VI	approved	Cabazitaxel	CO[C@H]1C[C@H]2OC[C@@]2(OC(C)=O)[C@H]2[C@H](OC(=O)C3=CC=CC=C3)[C@]3(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C4=CC=CC=C4)C(C)=C([C@@H](OC)C(=O)[C@]12C)C3(C)C
TUBB2B	DB07574	tubulin, beta 2B class IIb	experimental	2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE	COC1=CC2=C(C(OC)=C1OC)C1=CC=C(OC)C(=O)C=C1[C@H](CC2)NC(=O)CS
TUBB3	DB01873	tubulin, beta 3 class III	experimental; investigational	Epothilone D	C[C@H]1CCC\C(C)=C/C[C@@H](OC(=O)C[C@@H](O)C(C)(C)C(=O)[C@@H](C)[C@@H]1O)C(\C)=C\C1=CSC(C)=N1
TUBB3	DB03010	tubulin, beta 3 class III	experimental; investigational	Epothilone B	C[C@H]1CCC[C@]2(C)O[C@H]2C[C@H](OC(=O)C[C@@H](O)C(C)(C)C(=O)[C@@H](C)[C@@H]1O)C(\C)=C\C1=CSC(C)=N1
TUBB3	DB04845	tubulin, beta 3 class III	approved; investigational	Ixabepilone	C[C@H]1CCC[C@@]2(C)O[C@H]2C[C@H](NC(=O)C[C@@H](O)C(C)(C)C(=O)[C@@H](C)[C@H]1O)C(\C)=C\C1=CSC(C)=N1
TUBB4A	DB01873	tubulin, beta 4A class IVa	experimental; investigational	Epothilone D	C[C@H]1CCC\C(C)=C/C[C@@H](OC(=O)C[C@@H](O)C(C)(C)C(=O)[C@@H](C)[C@@H]1O)C(\C)=C\C1=CSC(C)=N1
TUBB4A	DB03010	tubulin, beta 4A class IVa	experimental; investigational	Epothilone B	C[C@H]1CCC[C@]2(C)O[C@H]2C[C@H](OC(=O)C[C@@H](O)C(C)(C)C(=O)[C@@H](C)[C@@H]1O)C(\C)=C\C1=CSC(C)=N1
TUBB4B	DB00518	tubulin, beta 4B class IVb	approved	Albendazole	CCCSC1=CC2=C(C=C1)N=C(NC(=O)OC)N2
TUBB4B	DB00643	tubulin, beta 4B class IVb	approved	Mebendazole	COC(=O)NC1=NC2=C(N1)C=C(C=C2)C(=O)C1=CC=CC=C1
TUBB4B	DB01873	tubulin, beta 4B class IVb	experimental; investigational	Epothilone D	C[C@H]1CCC\C(C)=C/C[C@@H](OC(=O)C[C@@H](O)C(C)(C)C(=O)[C@@H](C)[C@@H]1O)C(\C)=C\C1=CSC(C)=N1
TUBB4B	DB03010	tubulin, beta 4B class IVb	experimental; investigational	Epothilone B	C[C@H]1CCC[C@]2(C)O[C@H]2C[C@H](OC(=O)C[C@@H](O)C(C)(C)C(=O)[C@@H](C)[C@@H]1O)C(\C)=C\C1=CSC(C)=N1
TXN	DB00130	thioredoxin	approved; nutraceutical; investigational	L-Glutamine	N[C@@H](CCC(N)=O)C(O)=O
TXNDC12	DB00143	thioredoxin domain containing 12 (endoplasmic reticulum)	approved; nutraceutical	Glutathione	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
TXNRD1	DB01169	thioredoxin reductase 1	approved; investigational	Arsenic trioxide	O1[As]2O[As]1O2
TXNRD1	DB02338	thioredoxin reductase 1	experimental	Nadph Dihydro-Nicotinamide-Adenine-Dinucleotidephosphate	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@@H](CO[P@](O)(=O)O[P@@](O)(=O)OC[C@@H]2O[C@H]([C@H](OP(O)(O)=O)[C@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@H]1O
TXNRD1	DB03147	thioredoxin reductase 1	experimental	Flavin-Adenine Dinucleotide	CC1=CC2=C(C=C1C)N(C[C@H](O)[C@H](O)[C@H](O)CO[P@](O)(=O)O[P@@](O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC3=C1N=CN=C3N)C1=NC(=O)NC(=O)C1=N2
TXNRD1	DB03566	thioredoxin reductase 1	experimental	Spermidine	NCCCCNCCCN
TXNRD1	DB04106	thioredoxin reductase 1	experimental	Fotemustine	CCOP(=O)(OCC)[C@@H](C)NC(=O)N(CCCl)N=O
TXNRD2	DB01156	thioredoxin reductase 2	approved	Bupropion	CC(NC(C)(C)C)C(=O)C1=CC(Cl)=CC=C1
TYMP	DB03462	thymidine phosphorylase	experimental	Thymine	CC1=CNC(=O)NC1=O
TYMP	DB02631	thymidine phosphorylase	experimental	5-Chloro-6-[(2-Iminopyrrolidin-1-Yl)Methyl]Pyrimidine-2,4(1h,3h)-Dione	ClC1=C(CN2CCCC2=N)NC(=O)NC1=O
TYMP	DB01101	thymidine phosphorylase	approved; investigational	Capecitabine	CCCCCOC(=O)NC1=NC(=O)N(C=C1F)[C@@H]1O[C@H](C)[C@@H](O)[C@H]1O
TYMP	DB00544	thymidine phosphorylase	approved	Fluorouracil	FC1=CNC(=O)NC1=O
TYMP	DB02745	thymidine phosphorylase	experimental	Uridine	OC[C@@H]1O[C@H]([C@H](O)[C@H]1O)N1C=CC(=O)NC1=O
TYMS	DB01099	thymidylate synthetase	approved	Flucytosine	NC1=C(F)C=NC(=O)N1
TYMS	DB00293	thymidylate synthetase	approved; investigational	Raltitrexed	CN(CC1=CC2=C(NC(C)=NC2=O)C=C1)C1=CC=C(S1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
TYMS	DB00322	thymidylate synthetase	approved	Floxuridine	OC[C@H]1O[C@H](C[C@@H]1O)N1C=C(F)C(=O)NC1=O
TYMS	DB00432	thymidylate synthetase	approved	Trifluridine	OC[C@H]1O[C@H](C[C@@H]1O)N1C=C(C(=O)NC1=O)C(F)(F)F
TYMS	DB00440	thymidylate synthetase	approved	Trimethoprim	COC1=CC(CC2=CN=C(N)N=C2N)=CC(OC)=C1OC
TYMS	DB00441	thymidylate synthetase	approved	Gemcitabine	NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](CO)[C@@H](O)C1(F)F
TYMS	DB00544	thymidylate synthetase	approved	Fluorouracil	FC1=CNC(=O)NC1=O
TYMS	DB00642	thymidylate synthetase	approved; investigational	Pemetrexed	NC1=NC(=O)C2=C(NC=C2CCC2=CC=C(C=C2)C(=O)N[C@H](CCC(O)=O)C(O)=O)N1
TYMS	DB00650	thymidylate synthetase	approved	Leucovorin	NC1=NC(=O)C2=C(NCC(CNC3=CC=C(C=C3)C(=O)N[C@H](CCC(O)=O)C(O)=O)N2C=O)N1
TYMS	DB01101	thymidylate synthetase	approved; investigational	Capecitabine	CCCCCOC(=O)NC1=NC(=O)N(C=C1F)[C@@H]1O[C@H](C)[C@@H](O)[C@H]1O
TYMS	DB01643	thymidylate synthetase	experimental	Thymidine-5'-Phosphate	CC1=CN([C@H]2C[C@H](O)[C@@H](COP(O)(O)=O)O2)C(=O)NC1=O
TYMS	DB03541	thymidylate synthetase	experimental	10-Propargyl-5,8-Dideazafolic Acid	NC1=NC(=O)C2=CC(CN(CC#C)C3=CC=C(C=C3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)=CC=C2N1
TYMS	DB03800	thymidylate synthetase	experimental	2'-deoxyuridylic acid	O[C@H]1C[C@@H](O[C@@H]1COP(O)(O)=O)N1C=CC(=O)NC1=O
TYMS	DB04530	thymidylate synthetase	experimental	S,S-(2-Hydroxyethyl)Thiocysteine	N[C@@H](CSSCCO)C(O)=O
TYMS	DB07577	thymidylate synthetase	experimental	6-ETHYL-5-PHENYLPYRIMIDINE-2,4-DIAMINE	CCC1=NC(N)=NC(N)=C1C1=CC=CC=C1
TYMS	DB08478	thymidylate synthetase	experimental	N-[2-chloro-5-(trifluoromethyl)phenyl]imidodicarbonimidic diamide	NC(=N)NC(=N)NC1=C(Cl)C=CC(=C1)C(F)(F)F
TYMS	DB08479	thymidylate synthetase	experimental	N-(3,5-dimethoxyphenyl)imidodicarbonimidic diamide	COC1=CC(OC)=CC(NC(=N)NC(N)=N)=C1
TYMS	DB08734	thymidylate synthetase	experimental	6,6-DIMETHYL-1-[3-(2,4,5-TRICHLOROPHENOXY)PROPOXY]-1,6-DIHYDRO-1,3,5-TRIAZINE-2,4-DIAMINE	CC1(C)N=C(N)N=C(N)N1OCCCOC1=CC(Cl)=C(Cl)C=C1Cl
TYMS	DB02031	thymidylate synthetase	experimental	(6s)-5,6,7,8-Tetrahydrofolate	NC1=NC2=C(N[C@H](CNC3=CC=C(C=C3)C(=O)N[C@H](CCC(O)=O)C(O)=O)CN2)C(=O)N1
TYMS	DB02223	thymidylate synthetase	experimental	Ly231514 Tetra Glu	NC1=Nc2ncc(CCC3=CC=C(C=C3)C(=O)N[C@H](CCC(=O)N[C@@H](CCC(=O)N[C@H](CCC(=O)N[C@@H](CCC(O)=O)C(O)=O)C(O)=O)C(O)=O)C(O)=O)c2C(=O)N1
TYMS	DB02256	thymidylate synthetase	experimental	2'-Deoxyuridine	OC[C@H]1O[C@@H](C[C@@H]1O)N1C=CC(=O)NC1=O
TYMS	DB02301	thymidylate synthetase	experimental	5,10-Methylene-6-Hydrofolic Acid	NC1=NC(=O)C2=C(N1)N=C[C@@H]1CN(CN21)C1=CC=C(C=C1)C(=O)N[C@H](CCC(O)=O)C(O)=O
TYMS	DB02467	thymidylate synthetase	experimental	S-Oxymethionine	C[S@](=O)CC[C@@H](N)C(O)=O
TYMS	DB02752	thymidylate synthetase	experimental	Tosyl-D-Proline	CC1=CC=C(C=C1)S(=O)(=O)N1CCC[C@@H]1C(O)=O
TYMS	DB02899	thymidylate synthetase	experimental	N-Carboxymethionine	CSCC[C@H](NC(O)=O)C(O)=O
TYMS	DB03038	thymidylate synthetase	experimental	LY341770	NC1=Nc2ncc(CCC3=CC=C(C=C3)C(=O)N[C@H](CCc3nnnn3)C(O)=O)c2C(=O)N1
TYMS	DB03157	thymidylate synthetase	experimental	N,O-Didansyl-L-Tyrosine	CN(C)C1=CC=CC2=C1C=CC=C2S(=O)(=O)N[C@H](CC1=CC=C(OS(=O)(=O)C2=CC=CC3=C2C=CC=C3N(C)C)C=C1)C(O)=O
TYMS	DB03274	thymidylate synthetase	experimental	2'-5'dideoxyuridine	C[C@H]1O[C@@H](C[C@@H]1O)N1C=CC(=O)NC1=O
TYMS	DB03558	thymidylate synthetase	experimental	Sp-876	OC(=O)CCNC(=O)[C@@H]1CCCN1S(=O)(=O)C1=CC=C(C=C1)C(=O)N[C@H](CCC(O)=O)C(O)=O
TYMS	DB03761	thymidylate synthetase	experimental	5-Fluoro-2'-Deoxyuridine-5'-Monophosphate	O[C@@H]1C[C@@H](O[C@H]1COP(O)(O)=O)N1C=C(F)C(=O)NC1=O
TYMS	DB03818	thymidylate synthetase	experimental	N-[Tosyl-D-Prolinyl]Amino-Ethanethiol	CC1=CC=C(C=C1)S(=O)(=O)N1CCC[C@@H]1C(=O)NCCS
TYMS	DB04447	thymidylate synthetase	experimental	1,4-Dithiothreitol	O[C@H](CS)[C@H](O)CS
TYMS	DB04457	thymidylate synthetase	experimental	2'-Deoxyguanosine-5'-Monophosphate	NC1=NC(=O)C2=C(N1)N(C=N2)[C@H]1C[C@H](O)[C@@H](COP(O)(O)=O)O1
TYMS	DB04503	thymidylate synthetase	experimental	Sp-722	OC(=O)CC[C@H](NC(=O)C1=CC=C(C=C1)S(=O)(=O)N1CCC[C@@H]1C(O)=O)C(O)=O
TYMS	DB04586	thymidylate synthetase	experimental	2-bromophenol	OC1=CC=CC=C1Br
TYMS	DB04696	thymidylate synthetase	experimental	4-CHLORO-3',3''-DIBROMOPHENOL-1,8-NAPHTHALEIN	OC1=C(Br)C=C(C=C1)C1(OC(=O)C2=C3C(C=CC=C13)=C(Cl)C=C2)C1=CC(Br)=C(O)C=C1
TYMS	DB08131	thymidylate synthetase	experimental	2-{4-[2-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-ETHYL]-BENZOYLAMINO}-3-METHYL-BUTYRIC ACID	CC(C)[C@H](NC(=O)C1=CC=C(CCC2=CNC3=C2C(=O)NC(N)=N3)C=C1)C(O)=O
TYMS	DB03685	thymidylate synthetase	experimental	Uridine-5'-Monophosphate	O[C@@H]1[C@@H](O)[C@@H](O[C@H]1COP(O)(O)=O)N1C=CC(=O)NC1=O
TYMS	DB03798	thymidylate synthetase	experimental	2'-Deoxycytidine-5'-Monophosphate	NC1=NC(=O)N(C=C1)[C@H]1C[C@@H](O)[C@H](COP(O)(O)=O)O1
TYMS	DB06860	thymidylate synthetase	experimental	2-(2-chloropyridin-4-yl)-4-methyl-1H-isoindole-1,3(2H)-dione	CC1=C2C(=O)N(C(=O)C2=CC=C1)C1=CC=NC(Cl)=C1
TYMS	DB07507	thymidylate synthetase	experimental	2-(4-hydroxybiphenyl-3-yl)-4-methyl-1H-isoindole-1,3(2H)-dione	CC1=C2C(=O)N(C(=O)C2=CC=C1)C1=CC(=CC=C1O)C1=CC=CC=C1
TYMS	DB07511	thymidylate synthetase	experimental	4-(4-methyl-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)benzonitrile	CC1=C2C(=O)N(C(=O)C2=CC=C1)C1=CC=C(C=C1)C#N
TYMS	DB08204	thymidylate synthetase	experimental	3-DIPHENOL-6-NITRO-3H-BENZO[DE]ISOCHROMEN-1-ONE	OC1=CC=C(C=C1)C1(OC(=O)C2=CC=CC3=C(C=CC1=C23)[N+]([O-])=O)C1=CC=C(O)C=C1
TYMS	DB01234	thymidylate synthetase	approved; investigational	Dexamethasone	C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
TYMS	DB00531	thymidylate synthetase	approved; investigational	Cyclophosphamide	ClCCN(CCCl)P1(=O)NCCCO1
TYMS	DB00970	thymidylate synthetase	approved	Dactinomycin	CC(C)C1NC(=O)C(NC(=O)C2=C3N=C4C(OC3=C(C)C=C2)=C(C)C(=O)C(N)=C4C(=O)NC2C(C)OC(=O)C(C(C)C)N(C)C(=O)CN(C)C(=O)C3CCCN3C(=O)C(NC2=O)C(C)C)C(C)OC(=O)C(C(C)C)N(C)C(=O)CN(C)C(=O)C2CCCN2C1=O
TYMS	DB00997	thymidylate synthetase	approved; investigational	Doxorubicin	COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3O[C@H]3C[C@H](N)[C@H](O)[C@H](C)O3)C(=O)CO)C(O)=C1C2=O
TYMS	DB01611	thymidylate synthetase	approved	Hydroxychloroquine	CCN(CCO)CCCC(C)NC1=C2C=CC(Cl)=CC2=NC=C1
TYMS	DB00795	thymidylate synthetase	approved	Sulfasalazine	OC(=O)C1=CC(=CC=C1O)\N=N\C1=CC=C(C=C1)S(=O)(=O)NC1=NC=CC=C1
TYMS	DB00130	thymidylate synthetase	approved; nutraceutical; investigational	L-Glutamine	N[C@@H](CCC(N)=O)C(O)=O
TYMS	DB00515	thymidylate synthetase	approved	Cisplatin	N[Pt](N)(Cl)Cl
TYMS	DB00115	thymidylate synthetase	approved; nutraceutical	Cyanocobalamin	[C@@H]1([C@H]2N3C4=C(C5=[N]6C(C([C@@H]5CCC(N)=O)(C)C)=CC5=[N]7C(=C(C8=[N]([C@@]2([C@@]([C@@H]8CCC(N)=O)(C)CC(N)=O)C)[Co]367([N]2=CN(C3=CC(=C(C)C=C23)C)[C@H]2O[C@H](CO)[C@@H](OP(O)(=O)O[C@H](C)CNC(=O)CC[C@]14C)[C@H]2O)C#N)C)[C@@]([C@@H]5CCC(N)=O)(C)CC(N)=O)C)CC(N)=O
TYMS	DB00158	thymidylate synthetase	approved; nutraceutical	Folic Acid	NC1=NC(=O)C2=NC(CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)=CN=C2N1
TYMS	DB00165	thymidylate synthetase	approved; nutraceutical	Pyridoxine	CC1=NC=C(CO)C(CO)=C1O
TYMS	DB00526	thymidylate synthetase	approved; investigational	Oxaliplatin	O=C1O[Pt]2(N[C@@H]3CCCC[C@H]3N2)OC1=O
TYMS	DB00987	thymidylate synthetase	approved; investigational	Cytarabine	NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O
TYMS	DB00694	thymidylate synthetase	approved	Daunorubicin	COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3O[C@H]3C[C@H](N)[C@H](O)[C@H](C)O3)C(C)=O)C(O)=C1C2=O
TYMS	DB00773	thymidylate synthetase	approved	Etoposide	COC1=CC(=CC(OC)=C1O)[C@H]1[C@@H]2[C@H](COC2=O)[C@H](O[C@@H]2O[C@@H]3CO[C@@H](C)O[C@H]3[C@H](O)[C@H]2O)C2=CC3=C(OCO3)C=C12
TYMS	DB01033	thymidylate synthetase	approved	Mercaptopurine	S=C1N=CNC2=C1NC=N2
TYMS	DB00563	thymidylate synthetase	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
TYMS	DB00635	thymidylate synthetase	approved	Prednisone	C[C@]12CC(=O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
TYMS	DB00541	thymidylate synthetase	approved; investigational	Vincristine	CC[C@]1(O)C[C@H]2CN(C1)CCC1=C(NC3=CC=CC=C13)[C@@](C2)(C(=O)OC)C1=C(OC)C=C2N(C=O)[C@@H]3[C@]4(CCN5CC=C[C@](CC)([C@@H]45)[C@@H](OC(C)=O)[C@]3(O)C(=O)OC)C2=C1
TYMS	DB00762	thymidylate synthetase	approved; investigational	Irinotecan	CCC1=C2CN3C(=CC4=C(COC(=O)[C@]4(O)CC)C3=O)C2=NC2=C1C=C(OC(=O)N1CCC(CC1)N1CCCCC1)C=C2
TYMS	DB01050	thymidylate synthetase	approved	Ibuprofen	CC(C)CC1=CC=C(C=C1)C(C)C(O)=O
TYMS	DB00958	thymidylate synthetase	approved	Carboplatin	N.N.O=C1O[Pt]OC(=O)C11CCC1
TYR	DB00157	tyrosinase	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
TYR	DB00548	tyrosinase	approved	Azelaic Acid	OC(=O)CCCCCCCC(O)=O
TYR	DB00600	tyrosinase	approved	Monobenzone	OC1=CC=C(OCC2=CC=CC=C2)C=C1
TYR	DB01055	tyrosinase	approved	Mimosine	N[C@@H](CN1C=CC(=O)C(O)=C1)C(O)=O
UAP1	DB02196	UDP-N-acteylglucosamine pyrophosphorylase 1	experimental	Uridine-Diphosphate-N-Acetylgalactosamine	CC(=O)N[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1O[P@](O)(=O)O[P@](O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=CC(=O)NC1=O
UAP1	DB03397	UDP-N-acteylglucosamine pyrophosphorylase 1	experimental	Uridine-Diphosphate-N-Acetylglucosamine	CC(=O)N[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[P@](O)(=O)O[P@](O)(=O)OC[C@@H]1O[C@H]([C@H](O)[C@H]1O)N1C=CC(=O)NC1=O
UCK1	DB02745	uridine-cytidine kinase 1	experimental	Uridine	OC[C@@H]1O[C@H]([C@H](O)[C@H]1O)N1C=CC(=O)NC1=O
UCK2	DB02097	uridine-cytidine kinase 2	experimental	Cytidine	NC1=NC(=O)N(C=C1)[C@@H]1O[C@@H](CO)[C@H](O)[C@H]1O
UCK2	DB02431	uridine-cytidine kinase 2	experimental	Cytidine-5'-Triphosphate	NC1=NC(=O)N(C=C1)[C@@H]1O[C@@H](CO[P@](O)(=O)O[P@@](O)(=O)OP(O)(O)=O)[C@H](O)[C@H]1O
UCK2	DB03403	uridine-cytidine kinase 2	experimental	Cytidine-5'-Monophosphate	NC1=NC(=O)N(C=C1)[C@@H]1O[C@@H](COP(O)(O)=O)[C@H](O)[C@H]1O
UCK2	DB03431	uridine-cytidine kinase 2	experimental	Adenosine-5'-Diphosphate	NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H](CO[P@](O)(=O)OP(O)(O)=O)[C@H](O)[C@H]1O
UCK2	DB04005	uridine-cytidine kinase 2	experimental	Uridine 5'-Triphosphate	O[C@@H]1[C@@H](O)[C@@H](O[C@H]1CO[P@](O)(=O)O[P@@](O)(=O)OP(O)(O)=O)N1C=CC(=O)NC1=O
UCK2	DB04272	uridine-cytidine kinase 2	experimental	Citric Acid	OC(=O)CC(O)(CC(O)=O)C(O)=O
UCK2	DB02745	uridine-cytidine kinase 2	experimental	Uridine	OC[C@@H]1O[C@H]([C@H](O)[C@H]1O)N1C=CC(=O)NC1=O
UCK2	DB00544	uridine-cytidine kinase 2	approved	Fluorouracil	FC1=CNC(=O)NC1=O
UCK2	DB00563	uridine-cytidine kinase 2	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
UGDH	DB00157	UDP-glucose 6-dehydrogenase	approved; nutraceutical	NADH	NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
UGDH	DB01713	UDP-glucose 6-dehydrogenase	experimental	Udp-Alpha-D-Xylopyranose	O[C@H]1[C@H](CO[P@](O)(=O)O[P@@](O)(=O)O[C@@H]2OC[C@H](O)[C@H](O)[C@H]2O)O[C@H]([C@@H]1O)N1C=CC(=O)NC1=O
UGDH	DB01907	UDP-glucose 6-dehydrogenase	experimental	Nicotinamide-Adenine-Dinucleotide	NC(=O)C1=CC=C[N+](=C1)[C@H]1O[C@@H](CO[P@]([O-])(=O)O[P@@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@H](O)[C@@H]1O
UGDH	DB03041	UDP-glucose 6-dehydrogenase	experimental	Udp-Glucuronic Acid	O[C@H]1[C@H](CO[P@@](O)(=O)O[P@@](O)(=O)O[C@H]2O[C@H]([C@H](O)[C@@H](O)[C@@H]2O)C(O)=O)O[C@H]([C@@H]1O)N1C=CC(=O)NC1=O
UGT1A1	DB01234	UDP glucuronosyltransferase 1 family, polypeptide A1	approved; investigational	Dexamethasone	C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
UGT1A1	DB01544	UDP glucuronosyltransferase 1 family, polypeptide A1	illicit; approved	Flunitrazepam	CN1C2=C(C=C(C=C2)[N+]([O-])=O)C(=NCC1=O)C1=CC=CC=C1F
UGT1A1	DB00973	UDP glucuronosyltransferase 1 family, polypeptide A1	approved	Ezetimibe	O[C@@H](CC[C@@H]1[C@H](N(C1=O)C1=CC=C(F)C=C1)C1=CC=C(O)C=C1)C1=CC=C(F)C=C1
UGT1A1	DB00317	UDP glucuronosyltransferase 1 family, polypeptide A1	approved; investigational	Gefitinib	COC1=C(OCCCN2CCOCC2)C=C2C(NC3=CC(Cl)=C(F)C=C3)=NC=NC2=C1
UGT1A1	DB00683	UDP glucuronosyltransferase 1 family, polypeptide A1	illicit; approved	Midazolam	CC1=NC=C2CN=C(C3=CC=CC=C3F)C3=C(C=CC(Cl)=C3)N12
UGT1A1	DB00184	UDP glucuronosyltransferase 1 family, polypeptide A1	approved	Nicotine	CN1CCCC1C1=CN=CC=C1
UGT1A1	DB00196	UDP glucuronosyltransferase 1 family, polypeptide A1	approved	Fluconazole	OC(CN1C=NC=N1)(CN1C=NC=N1)C1=C(F)C=C(F)C=C1
UGT1A1	DB01026	UDP glucuronosyltransferase 1 family, polypeptide A1	approved; investigational	Ketoconazole	CC(=O)N1CCN(CC1)C1=CC=C(OC[C@@H]2CO[C@](CN3C=CN=C3)(O2)C2=C(Cl)C=C(Cl)C=C2)C=C1
UGT1A1	DB00318	UDP glucuronosyltransferase 1 family, polypeptide A1	illicit; approved	Codeine	COC1=C2O[C@H]3[C@@H](O)C=C[C@H]4[C@H]5CC(C=C1)=C2[C@@]34CCN5C
UGT1A1	DB00678	UDP glucuronosyltransferase 1 family, polypeptide A1	approved	Losartan	CCCCC1=NC(Cl)=C(CO)N1CC1=CC=C(C=C1)C1=CC=CC=C1C1=NNN=N1
UGT1A1	DB00530	UDP glucuronosyltransferase 1 family, polypeptide A1	approved; investigational	Erlotinib	COCCOC1=C(OCCOC)C=C2C(NC3=CC=CC(=C3)C#C)=NC=NC2=C1
UGT1A1	DB01156	UDP glucuronosyltransferase 1 family, polypeptide A1	approved	Bupropion	CC(NC(C)(C)C)C(=O)C1=CC(Cl)=CC=C1
UGT1A1	DB00564	UDP glucuronosyltransferase 1 family, polypeptide A1	approved; investigational	Carbamazepine	NC(=O)N1C2=CC=CC=C2C=CC2=CC=CC=C12
UGT1A1	DB00531	UDP glucuronosyltransferase 1 family, polypeptide A1	approved; investigational	Cyclophosphamide	ClCCN(CCCl)P1(=O)NCCCO1
UGT1A1	DB00625	UDP glucuronosyltransferase 1 family, polypeptide A1	approved; investigational	Efavirenz	FC(F)(F)[C@]1(OC(=O)NC2=C1C=C(Cl)C=C2)C#CC1CC1
UGT1A1	DB00532	UDP glucuronosyltransferase 1 family, polypeptide A1	approved	Mephenytoin	CCC1(NC(=O)N(C)C1=O)C1=CC=CC=C1
UGT1A1	DB00238	UDP glucuronosyltransferase 1 family, polypeptide A1	approved	Nevirapine	CC1=C2NC(=O)C3=C(N=CC=C3)N(C3CC3)C2=NC=C1
UGT1A1	DB01045	UDP glucuronosyltransferase 1 family, polypeptide A1	approved	Rifampin	CO[C@H]1\C=C\O[C@@]2(C)OC3=C(C)C(O)=C4C(O)=C(NC(=O)\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@H](O)[C@H](C)[C@H](OC(C)=O)[C@@H]1C)C(\C=N\N1CCN(C)CC1)=C(O)C4=C3C2=O
UGT1A1	DB01076	UDP glucuronosyltransferase 1 family, polypeptide A1	approved	Atorvastatin	CC(C)C1=C(C(=O)NC2=CC=CC=C2)C(=C(N1CC[C@@H](O)C[C@@H](O)CC(O)=O)C1=CC=C(F)C=C1)C1=CC=CC=C1
UGT1A1	DB00252	UDP glucuronosyltransferase 1 family, polypeptide A1	approved	Phenytoin	O=C1NC(=O)C(N1)(C1=CC=CC=C1)C1=CC=CC=C1
UGT1A1	DB00286	UDP glucuronosyltransferase 1 family, polypeptide A1	approved	Conjugated Estrogens	[Na+].C[C@]12CC[C@H]3[C@@H](CCC4=CC(OS([O-])(=O)=O)=CC=C34)[C@@H]1CCC2=O
UGT1A1	DB01601	UDP glucuronosyltransferase 1 family, polypeptide A1	approved	Lopinavir	CC(C)[C@H](N1CCCNC1=O)C(=O)N[C@H](C[C@H](O)[C@H](CC1=CC=CC=C1)NC(=O)COC1=C(C)C=CC=C1C)CC1=CC=CC=C1
UGT1A1	DB00503	UDP glucuronosyltransferase 1 family, polypeptide A1	approved; investigational	Ritonavir	CC(C)[C@H](NC(=O)N(C)CC1=CSC(=N1)C(C)C)C(=O)N[C@H](C[C@H](O)[C@H](CC1=CC=CC=C1)NC(=O)OCC1=CN=CS1)CC1=CC=CC=C1
UGT1A1	DB00322	UDP glucuronosyltransferase 1 family, polypeptide A1	approved	Floxuridine	OC[C@H]1O[C@H](C[C@@H]1O)N1C=C(F)C(=O)NC1=O
UGT1A1	DB00526	UDP glucuronosyltransferase 1 family, polypeptide A1	approved; investigational	Oxaliplatin	O=C1O[Pt]2(N[C@@H]3CCCC[C@H]3N2)OC1=O
UGT1A1	DB00295	UDP glucuronosyltransferase 1 family, polypeptide A1	approved; investigational	Morphine	CN1CC[C@]23[C@H]4OC5=C(O)C=CC(C[C@@H]1[C@@H]2C=C[C@@H]4O)=C35
UGT1A1	DB00958	UDP glucuronosyltransferase 1 family, polypeptide A1	approved	Carboplatin	N.N.O=C1O[Pt]OC(=O)C11CCC1
UGT1A1	DB01174	UDP glucuronosyltransferase 1 family, polypeptide A1	approved	Phenobarbital	CCC1(C(=O)NC(=O)NC1=O)C1=CC=CC=C1
UGT1A1	DB00987	UDP glucuronosyltransferase 1 family, polypeptide A1	approved; investigational	Cytarabine	NC1=NC(=O)N(C=C1)[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O
UGT1A1	DB00694	UDP glucuronosyltransferase 1 family, polypeptide A1	approved	Daunorubicin	COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3O[C@H]3C[C@H](N)[C@H](O)[C@H](C)O3)C(C)=O)C(O)=C1C2=O
UGT1A1	DB00773	UDP glucuronosyltransferase 1 family, polypeptide A1	approved	Etoposide	COC1=CC(=CC(OC)=C1O)[C@H]1[C@@H]2[C@H](COC2=O)[C@H](O[C@@H]2O[C@@H]3CO[C@@H](C)O[C@H]3[C@H](O)[C@H]2O)C2=CC3=C(OCO3)C=C12
UGT1A1	DB00650	UDP glucuronosyltransferase 1 family, polypeptide A1	approved	Leucovorin	NC1=NC(=O)C2=C(NCC(CNC3=CC=C(C=C3)C(=O)N[C@H](CCC(O)=O)C(O)=O)N2C=O)N1
UGT1A1	DB01033	UDP glucuronosyltransferase 1 family, polypeptide A1	approved	Mercaptopurine	S=C1N=CNC2=C1NC=N2
UGT1A1	DB00563	UDP glucuronosyltransferase 1 family, polypeptide A1	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
UGT1A1	DB00635	UDP glucuronosyltransferase 1 family, polypeptide A1	approved	Prednisone	C[C@]12CC(=O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO
UGT1A1	DB00541	UDP glucuronosyltransferase 1 family, polypeptide A1	approved; investigational	Vincristine	CC[C@]1(O)C[C@H]2CN(C1)CCC1=C(NC3=CC=CC=C13)[C@@](C2)(C(=O)OC)C1=C(OC)C=C2N(C=O)[C@@H]3[C@]4(CCN5CC=C[C@](CC)([C@@H]45)[C@@H](OC(C)=O)[C@]3(O)C(=O)OC)C2=C1
UGT1A1	DB00762	UDP glucuronosyltransferase 1 family, polypeptide A1	approved; investigational	Irinotecan	CCC1=C2CN3C(=CC4=C(COC(=O)[C@]4(O)CC)C3=O)C2=NC2=C1C=C(OC(=O)N1CCC(CC1)N1CCCCC1)C=C2
UGT1A1	DB00224	UDP glucuronosyltransferase 1 family, polypeptide A1	approved	Indinavir	CC(C)(C)NC(=O)[C@@H]1CN(CC2=CN=CC=C2)CCN1C[C@@H](O)C[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]1[C@H](O)CC2=CC=CC=C12
UGT1A1	DB01072	UDP glucuronosyltransferase 1 family, polypeptide A1	approved; investigational	Atazanavir	COC(=O)N[C@H](C(=O)N[C@@H](CC1=CC=CC=C1)[C@@H](O)CN(CC1=CC=C(C=C1)C1=CC=CC=N1)NC(=O)[C@@H](NC(=O)OC)C(C)(C)C)C(C)(C)C
UGT1A1	DB00624	UDP glucuronosyltransferase 1 family, polypeptide A1	approved; investigational	Testosterone	C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CC[C@@H]2O
UGT1A1	DB00783	UDP glucuronosyltransferase 1 family, polypeptide A1	approved; investigational	Estradiol	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CC[C@@H]2O
UGT1A1	DB00544	UDP glucuronosyltransferase 1 family, polypeptide A1	approved	Fluorouracil	FC1=CNC(=O)NC1=O
UGT1A1	DB01101	UDP glucuronosyltransferase 1 family, polypeptide A1	approved; investigational	Capecitabine	CCCCCOC(=O)NC1=NC(=O)N(C=C1F)[C@@H]1O[C@H](C)[C@@H](O)[C@H]1O
UGT1A1	DB01110	UDP glucuronosyltransferase 1 family, polypeptide A1	approved; investigational	Miconazole	ClC1=CC(Cl)=C(COC(CN2C=CN=C2)C2=C(Cl)C=C(Cl)C=C2)C=C1
UGT1A1	DB00338	UDP glucuronosyltransferase 1 family, polypeptide A1	approved; investigational	Omeprazole	COC1=CC2=C(C=C1)N=C(N2)S(=O)CC1=NC=C(C)C(OC)=C1C
UGT1A1	DB00515	UDP glucuronosyltransferase 1 family, polypeptide A1	approved	Cisplatin	N[Pt](N)(Cl)Cl
UGT1A1	DB00316	UDP glucuronosyltransferase 1 family, polypeptide A1	approved	Acetaminophen	CC(=O)NC1=CC=C(O)C=C1
UGT1A1	DB00921	UDP glucuronosyltransferase 1 family, polypeptide A1	illicit; approved; investigational	Buprenorphine	CO[C@]12CC[C@@]3(C[C@@H]1[C@](C)(O)C(C)(C)C)[C@H]1CC4=C5C(O[C@@H]2[C@@]35CCN1CC1CC1)=C(O)C=C4
UGT1A1	DB00977	UDP glucuronosyltransferase 1 family, polypeptide A1	approved	Ethinyl Estradiol	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CC[C@@]2(O)C#C
UGT1A1	DB00966	UDP glucuronosyltransferase 1 family, polypeptide A1	approved; investigational	Telmisartan	CCCC1=NC2=C(C=C(C=C2C)C2=NC3=CC=CC=C3N2C)N1CC1=CC=C(C=C1)C1=CC=CC=C1C(O)=O
UGT1A1	DB00695	UDP glucuronosyltransferase 1 family, polypeptide A1	approved	Furosemide	NS(=O)(=O)C1=C(Cl)C=C(NCC2=CC=CO2)C(=C1)C(O)=O
UGT1A1	DB00712	UDP glucuronosyltransferase 1 family, polypeptide A1	approved	Flurbiprofen	CC(C(O)=O)C1=CC(F)=C(C=C1)C1=CC=CC=C1
UGT1A1	DB01050	UDP glucuronosyltransferase 1 family, polypeptide A1	approved	Ibuprofen	CC(C)CC1=CC=C(C=C1)C(C)C(O)=O
UGT1A1	DB01009	UDP glucuronosyltransferase 1 family, polypeptide A1	approved	Ketoprofen	CC(C(O)=O)C1=CC(=CC=C1)C(=O)C1=CC=CC=C1
UGT1A1	DB00451	UDP glucuronosyltransferase 1 family, polypeptide A1	approved	Levothyroxine	N[C@@H](CC1=CC(I)=C(OC2=CC(I)=C(O)C(I)=C2)C(I)=C1)C(O)=O
UGT1A10	DB00184	UDP glucuronosyltransferase 1 family, polypeptide A10	approved	Nicotine	CN1CCCC1C1=CN=CC=C1
UGT1A10	DB00818	UDP glucuronosyltransferase 1 family, polypeptide A10	approved; investigational	Propofol	CC(C)C1=CC=CC(C(C)C)=C1O
UGT1A10	DB00762	UDP glucuronosyltransferase 1 family, polypeptide A10	approved; investigational	Irinotecan	CCC1=C2CN3C(=CC4=C(COC(=O)[C@]4(O)CC)C3=O)C2=NC2=C1C=C(OC(=O)N1CCC(CC1)N1CCCCC1)C=C2
UGT1A10	DB00783	UDP glucuronosyltransferase 1 family, polypeptide A10	approved; investigational	Estradiol	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CC[C@@H]2O
UGT1A3	DB01544	UDP glucuronosyltransferase 1 family, polypeptide A3	illicit; approved	Flunitrazepam	CN1C2=C(C=C(C=C2)[N+]([O-])=O)C(=NCC1=O)C1=CC=CC=C1F
UGT1A3	DB00973	UDP glucuronosyltransferase 1 family, polypeptide A3	approved	Ezetimibe	O[C@@H](CC[C@@H]1[C@H](N(C1=O)C1=CC=C(F)C=C1)C1=CC=C(O)C=C1)C1=CC=C(F)C=C1
UGT1A3	DB00184	UDP glucuronosyltransferase 1 family, polypeptide A3	approved	Nicotine	CN1CCCC1C1=CN=CC=C1
UGT1A3	DB01076	UDP glucuronosyltransferase 1 family, polypeptide A3	approved	Atorvastatin	CC(C)C1=C(C(=O)NC2=CC=CC=C2)C(=C(N1CC[C@@H](O)C[C@@H](O)CC(O)=O)C1=CC=C(F)C=C1)C1=CC=CC=C1
UGT1A3	DB00762	UDP glucuronosyltransferase 1 family, polypeptide A3	approved; investigational	Irinotecan	CCC1=C2CN3C(=CC4=C(COC(=O)[C@]4(O)CC)C3=O)C2=NC2=C1C=C(OC(=O)N1CCC(CC1)N1CCCCC1)C=C2
UGT1A3	DB00783	UDP glucuronosyltransferase 1 family, polypeptide A3	approved; investigational	Estradiol	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CC[C@@H]2O
UGT1A3	DB00921	UDP glucuronosyltransferase 1 family, polypeptide A3	illicit; approved; investigational	Buprenorphine	CO[C@]12CC[C@@]3(C[C@@H]1[C@](C)(O)C(C)(C)C)[C@H]1CC4=C5C(O[C@@H]2[C@@]35CCN1CC1CC1)=C(O)C=C4
UGT1A3	DB00363	UDP glucuronosyltransferase 1 family, polypeptide A3	approved	Clozapine	CN1CCN(CC1)C1=NC2=CC(Cl)=CC=C2NC2=CC=CC=C12
UGT1A3	DB00434	UDP glucuronosyltransferase 1 family, polypeptide A3	approved	Cyproheptadine	CN1CCC(CC1)=C1C2=CC=CC=C2C=CC2=CC=CC=C12
UGT1A3	DB01075	UDP glucuronosyltransferase 1 family, polypeptide A3	approved	Diphenhydramine	CN(C)CCOC(C1=CC=CC=C1)C1=CC=CC=C1
UGT1A3	DB00678	UDP glucuronosyltransferase 1 family, polypeptide A3	approved	Losartan	CCCCC1=NC(Cl)=C(CO)N1CC1=CC=C(C=C1)C1=CC=CC=C1C1=NNN=N1
UGT1A3	DB00313	UDP glucuronosyltransferase 1 family, polypeptide A3	approved; investigational	Valproic Acid	CCCC(CCC)C(O)=O
UGT1A3	DB00655	UDP glucuronosyltransferase 1 family, polypeptide A3	approved	Estrone	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CCC2=O
UGT1A3	DB00712	UDP glucuronosyltransferase 1 family, polypeptide A3	approved	Flurbiprofen	CC(C(O)=O)C1=CC(F)=C(C=C1)C1=CC=CC=C1
UGT1A3	DB01050	UDP glucuronosyltransferase 1 family, polypeptide A3	approved	Ibuprofen	CC(C)CC1=CC=C(C=C1)C(C)C(O)=O
UGT1A3	DB01009	UDP glucuronosyltransferase 1 family, polypeptide A3	approved	Ketoprofen	CC(C(O)=O)C1=CC(=CC=C1)C(=O)C1=CC=CC=C1
UGT1A4	DB00252	UDP glucuronosyltransferase 1 family, polypeptide A4	approved	Phenytoin	O=C1NC(=O)C(N1)(C1=CC=CC=C1)C1=CC=CC=C1
UGT1A4	DB00683	UDP glucuronosyltransferase 1 family, polypeptide A4	illicit; approved	Midazolam	CC1=NC=C2CN=C(C3=CC=CC=C3F)C3=C(C=CC(Cl)=C3)N12
UGT1A4	DB00184	UDP glucuronosyltransferase 1 family, polypeptide A4	approved	Nicotine	CN1CCCC1C1=CN=CC=C1
UGT1A4	DB03255	UDP glucuronosyltransferase 1 family, polypeptide A4	experimental	Phenol	OC1=CC=CC=C1
UGT1A4	DB00675	UDP glucuronosyltransferase 1 family, polypeptide A4	approved	Tamoxifen	CC\C(=C(/C1=CC=CC=C1)C1=CC=C(OCCN(C)C)C=C1)C1=CC=CC=C1
UGT1A4	DB00762	UDP glucuronosyltransferase 1 family, polypeptide A4	approved; investigational	Irinotecan	CCC1=C2CN3C(=CC4=C(COC(=O)[C@]4(O)CC)C3=O)C2=NC2=C1C=C(OC(=O)N1CCC(CC1)N1CCCCC1)C=C2
UGT1A4	DB00477	UDP glucuronosyltransferase 1 family, polypeptide A4	approved	Chlorpromazine	CN(C)CCCN1C2=CC=CC=C2SC2=C1C=C(Cl)C=C2
UGT1A4	DB00363	UDP glucuronosyltransferase 1 family, polypeptide A4	approved	Clozapine	CN1CCN(CC1)C1=NC2=CC(Cl)=CC=C2NC2=CC=CC=C12
UGT1A4	DB00458	UDP glucuronosyltransferase 1 family, polypeptide A4	approved	Imipramine	CN(C)CCCN1C2=CC=CC=C2CCC2=CC=CC=C12
UGT1A4	DB00555	UDP glucuronosyltransferase 1 family, polypeptide A4	approved; investigational	Lamotrigine	NC1=NC(N)=C(N=N1)C1=C(Cl)C(Cl)=CC=C1
UGT1A4	DB00454	UDP glucuronosyltransferase 1 family, polypeptide A4	approved	Meperidine	CCOC(=O)C1(CCN(C)CC1)C1=CC=CC=C1
UGT1A4	DB00334	UDP glucuronosyltransferase 1 family, polypeptide A4	approved; investigational	Olanzapine	CN1CCN(CC1)C1=C2C=C(C)SC2=NC2=CC=CC=C2N1
UGT1A5	DB00762	UDP glucuronosyltransferase 1 family, polypeptide A5	approved; investigational	Irinotecan	CCC1=C2CN3C(=CC4=C(COC(=O)[C@]4(O)CC)C3=O)C2=NC2=C1C=C(OC(=O)N1CCC(CC1)N1CCCCC1)C=C2
UGT1A6	DB00252	UDP glucuronosyltransferase 1 family, polypeptide A6	approved	Phenytoin	O=C1NC(=O)C(N1)(C1=CC=CC=C1)C1=CC=CC=C1
UGT1A6	DB00184	UDP glucuronosyltransferase 1 family, polypeptide A6	approved	Nicotine	CN1CCCC1C1=CN=CC=C1
UGT1A6	DB00313	UDP glucuronosyltransferase 1 family, polypeptide A6	approved; investigational	Valproic Acid	CCCC(CCC)C(O)=O
UGT1A6	DB00316	UDP glucuronosyltransferase 1 family, polypeptide A6	approved	Acetaminophen	CC(=O)NC1=CC=C(O)C=C1
UGT1A6	DB00945	UDP glucuronosyltransferase 1 family, polypeptide A6	approved	Acetylsalicylic acid	CC(=O)OC1=CC=CC=C1C(O)=O
UGT1A6	DB00762	UDP glucuronosyltransferase 1 family, polypeptide A6	approved; investigational	Irinotecan	CCC1=C2CN3C(=CC4=C(COC(=O)[C@]4(O)CC)C3=O)C2=NC2=C1C=C(OC(=O)N1CCC(CC1)N1CCCCC1)C=C2
UGT1A6	DB00783	UDP glucuronosyltransferase 1 family, polypeptide A6	approved; investigational	Estradiol	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CC[C@@H]2O
UGT1A6	DB00338	UDP glucuronosyltransferase 1 family, polypeptide A6	approved; investigational	Omeprazole	COC1=CC2=C(C=C1)N=C(N2)S(=O)CC1=NC=C(C)C(OC)=C1C
UGT1A6	DB00788	UDP glucuronosyltransferase 1 family, polypeptide A6	approved	Naproxen	COC1=CC2=C(C=C1)C=C(C=C2)C(C)C(O)=O
UGT1A7	DB00317	UDP glucuronosyltransferase 1 family, polypeptide A7	approved; investigational	Gefitinib	COC1=C(OCCCN2CCOCC2)C=C2C(NC3=CC(Cl)=C(F)C=C3)=NC=NC2=C1
UGT1A7	DB00184	UDP glucuronosyltransferase 1 family, polypeptide A7	approved	Nicotine	CN1CCCC1C1=CN=CC=C1
UGT1A7	DB01026	UDP glucuronosyltransferase 1 family, polypeptide A7	approved; investigational	Ketoconazole	CC(=O)N1CCN(CC1)C1=CC=C(OC[C@@H]2CO[C@](CN3C=CN=C3)(O2)C2=C(Cl)C=C(Cl)C=C2)C=C1
UGT1A7	DB00224	UDP glucuronosyltransferase 1 family, polypeptide A7	approved	Indinavir	CC(C)(C)NC(=O)[C@@H]1CN(CC2=CN=CC=C2)CCN1C[C@@H](O)C[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]1[C@H](O)CC2=CC=CC=C12
UGT1A7	DB00196	UDP glucuronosyltransferase 1 family, polypeptide A7	approved	Fluconazole	OC(CN1C=NC=N1)(CN1C=NC=N1)C1=C(F)C=C(F)C=C1
UGT1A7	DB00818	UDP glucuronosyltransferase 1 family, polypeptide A7	approved; investigational	Propofol	CC(C)C1=CC=CC(C(C)C)=C1O
UGT1A7	DB00688	UDP glucuronosyltransferase 1 family, polypeptide A7	approved; investigational	Mycophenolate mofetil	COC1=C(C\C=C(/C)CCC(=O)OCCN2CCOCC2)C(O)=C2C(=O)OCC2=C1C
UGT1A7	DB00762	UDP glucuronosyltransferase 1 family, polypeptide A7	approved; investigational	Irinotecan	CCC1=C2CN3C(=CC4=C(COC(=O)[C@]4(O)CC)C3=O)C2=NC2=C1C=C(OC(=O)N1CCC(CC1)N1CCCCC1)C=C2
UGT1A8	DB01024	UDP glucuronosyltransferase 1 family, polypeptide A8	approved	Mycophenolic acid	COC1=C(C\C=C(/C)CCC(O)=O)C(O)=C2C(=O)OCC2=C1C
UGT1A8	DB00877	UDP glucuronosyltransferase 1 family, polypeptide A8	approved; investigational	Sirolimus	CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1O
UGT1A8	DB00864	UDP glucuronosyltransferase 1 family, polypeptide A8	approved; investigational	Tacrolimus	CO[C@@H]1C[C@@H](CC[C@H]1O)\C=C(/C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H]([C@H](C[C@H]2C)OC)[C@H](C[C@@H](C)C\C(C)=C\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]1C)OC
UGT1A8	DB00184	UDP glucuronosyltransferase 1 family, polypeptide A8	approved	Nicotine	CN1CCCC1C1=CN=CC=C1
UGT1A8	DB00295	UDP glucuronosyltransferase 1 family, polypeptide A8	approved; investigational	Morphine	CN1CC[C@]23[C@H]4OC5=C(O)C=CC(C[C@@H]1[C@@H]2C=C[C@@H]4O)=C35
UGT1A8	DB00318	UDP glucuronosyltransferase 1 family, polypeptide A8	illicit; approved	Codeine	COC1=C2O[C@H]3[C@@H](O)C=C[C@H]4[C@H]5CC(C=C1)=C2[C@@]34CCN5C
UGT1A8	DB00818	UDP glucuronosyltransferase 1 family, polypeptide A8	approved; investigational	Propofol	CC(C)C1=CC=CC(C(C)C)=C1O
UGT1A8	DB00688	UDP glucuronosyltransferase 1 family, polypeptide A8	approved; investigational	Mycophenolate mofetil	COC1=C(C\C=C(/C)CCC(=O)OCCN2CCOCC2)C(O)=C2C(=O)OCC2=C1C
UGT1A8	DB00762	UDP glucuronosyltransferase 1 family, polypeptide A8	approved; investigational	Irinotecan	CCC1=C2CN3C(=CC4=C(COC(=O)[C@]4(O)CC)C3=O)C2=NC2=C1C=C(OC(=O)N1CCC(CC1)N1CCCCC1)C=C2
UGT1A8	DB00655	UDP glucuronosyltransferase 1 family, polypeptide A8	approved	Estrone	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CCC2=O
UGT1A9	DB04552	UDP glucuronosyltransferase 1 family, polypeptide A9	approved	Niflumic Acid	OC(=O)C1=C(NC2=CC=CC(=C2)C(F)(F)F)N=CC=C1
UGT1A9	DB04824	UDP glucuronosyltransferase 1 family, polypeptide A9	withdrawn	Phenolphthalein	OC1=CC=C(C=C1)C1(OC(=O)C2=CC=CC=C12)C1=CC=C(O)C=C1
UGT1A9	DB00877	UDP glucuronosyltransferase 1 family, polypeptide A9	approved; investigational	Sirolimus	CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1O
UGT1A9	DB01024	UDP glucuronosyltransferase 1 family, polypeptide A9	approved	Mycophenolic acid	COC1=C(C\C=C(/C)CCC(O)=O)C(O)=C2C(=O)OCC2=C1C
UGT1A9	DB00252	UDP glucuronosyltransferase 1 family, polypeptide A9	approved	Phenytoin	O=C1NC(=O)C(N1)(C1=CC=CC=C1)C1=CC=CC=C1
UGT1A9	DB00842	UDP glucuronosyltransferase 1 family, polypeptide A9	approved	Oxazepam	OC1N=C(C2=CC=CC=C2)C2=C(NC1=O)C=CC(Cl)=C2
UGT1A9	DB00317	UDP glucuronosyltransferase 1 family, polypeptide A9	approved; investigational	Gefitinib	COC1=C(OCCCN2CCOCC2)C=C2C(NC3=CC(Cl)=C(F)C=C3)=NC=NC2=C1
UGT1A9	DB00864	UDP glucuronosyltransferase 1 family, polypeptide A9	approved; investigational	Tacrolimus	CO[C@@H]1C[C@@H](CC[C@H]1O)\C=C(/C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H]([C@H](C[C@H]2C)OC)[C@H](C[C@@H](C)C\C(C)=C\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]1C)OC
UGT1A9	DB00184	UDP glucuronosyltransferase 1 family, polypeptide A9	approved	Nicotine	CN1CCCC1C1=CN=CC=C1
UGT1A9	DB00224	UDP glucuronosyltransferase 1 family, polypeptide A9	approved	Indinavir	CC(C)(C)NC(=O)[C@@H]1CN(CC2=CN=CC=C2)CCN1C[C@@H](O)C[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]1[C@H](O)CC2=CC=CC=C12
UGT1A9	DB00196	UDP glucuronosyltransferase 1 family, polypeptide A9	approved	Fluconazole	OC(CN1C=NC=N1)(CN1C=NC=N1)C1=C(F)C=C(F)C=C1
UGT1A9	DB01026	UDP glucuronosyltransferase 1 family, polypeptide A9	approved; investigational	Ketoconazole	CC(=O)N1CCN(CC1)C1=CC=C(OC[C@@H]2CO[C@](CN3C=CN=C3)(O2)C2=C(Cl)C=C(Cl)C=C2)C=C1
UGT1A9	DB00398	UDP glucuronosyltransferase 1 family, polypeptide A9	approved; investigational	Sorafenib	CNC(=O)C1=NC=CC(OC2=CC=C(NC(=O)NC3=CC(=C(Cl)C=C3)C(F)(F)F)C=C2)=C1
UGT1A9	DB03496	UDP glucuronosyltransferase 1 family, polypeptide A9	experimental; investigational	Flavopiridol	CN1CC[C@@H]([C@H](O)C1)C1=C(O)C=C(O)C2=C1OC(=CC2=O)C1=CC=CC=C1Cl
UGT1A9	DB00818	UDP glucuronosyltransferase 1 family, polypeptide A9	approved; investigational	Propofol	CC(C)C1=CC=CC(C(C)C)=C1O
UGT1A9	DB00688	UDP glucuronosyltransferase 1 family, polypeptide A9	approved; investigational	Mycophenolate mofetil	COC1=C(C\C=C(/C)CCC(=O)OCCN2CCOCC2)C(O)=C2C(=O)OCC2=C1C
UGT1A9	DB00762	UDP glucuronosyltransferase 1 family, polypeptide A9	approved; investigational	Irinotecan	CCC1=C2CN3C(=CC4=C(COC(=O)[C@]4(O)CC)C3=O)C2=NC2=C1C=C(OC(=O)N1CCC(CC1)N1CCCCC1)C=C2
UGT1A9	DB00316	UDP glucuronosyltransferase 1 family, polypeptide A9	approved	Acetaminophen	CC(=O)NC1=CC=C(O)C=C1
UGT1A9	DB00355	UDP glucuronosyltransferase 1 family, polypeptide A9	approved	Aztreonam	C[C@H]1[C@H](NC(=O)C(=N\OC(C)(C)C(O)=O)\C2=CSC([NH3+])=N2)C(=O)N1S([O-])(=O)=O
UGT1A9	DB00250	UDP glucuronosyltransferase 1 family, polypeptide A9	approved; investigational	Dapsone	NC1=CC=C(C=C1)S(=O)(=O)C1=CC=C(N)C=C1
UGT1A9	DB00494	UDP glucuronosyltransferase 1 family, polypeptide A9	approved; investigational	Entacapone	CCN(CC)C(=O)C(=C\C1=CC(=C(O)C(O)=C1)[N+]([O-])=O)\C#N
UGT1A9	DB00598	UDP glucuronosyltransferase 1 family, polypeptide A9	approved	Labetalol	CC(CCC1=CC=CC=C1)NCC(O)C1=CC(C(N)=O)=C(O)C=C1
UGT1A9	DB00571	UDP glucuronosyltransferase 1 family, polypeptide A9	approved; investigational	Propranolol	CC(C)NCC(O)COC1=CC=CC2=CC=CC=C12
UGT1A9	DB00323	UDP glucuronosyltransferase 1 family, polypeptide A9	approved; withdrawn	Tolcapone	CC1=CC=C(C=C1)C(=O)C1=CC(=C(O)C(O)=C1)[N+]([O-])=O
UGT1A9	DB00695	UDP glucuronosyltransferase 1 family, polypeptide A9	approved	Furosemide	NS(=O)(=O)C1=C(Cl)C=C(NCC2=CC=CO2)C(=C1)C(O)=O
UGT1A9	DB06697	UDP glucuronosyltransferase 1 family, polypeptide A9	approved	Artemether	COC1OC2OC3(C)CCC4C(C)CCC(C1C)C24OO3
UGT1A9	DB00712	UDP glucuronosyltransferase 1 family, polypeptide A9	approved	Flurbiprofen	CC(C(O)=O)C1=CC(F)=C(C=C1)C1=CC=CC=C1
UGT1A9	DB01050	UDP glucuronosyltransferase 1 family, polypeptide A9	approved	Ibuprofen	CC(C)CC1=CC=C(C=C1)C(C)C(O)=O
UGT1A9	DB01009	UDP glucuronosyltransferase 1 family, polypeptide A9	approved	Ketoprofen	CC(C(O)=O)C1=CC(=CC=C1)C(=O)C1=CC=CC=C1
UGT1A9	DB00451	UDP glucuronosyltransferase 1 family, polypeptide A9	approved	Levothyroxine	N[C@@H](CC1=CC(I)=C(OC2=CC(I)=C(O)C(I)=C2)C(I)=C1)C(O)=O
UGT2B10	DB00184	UDP glucuronosyltransferase 2 family, polypeptide B10	approved	Nicotine	CN1CCCC1C1=CN=CC=C1
UGT2B15	DB00675	UDP glucuronosyltransferase 2 family, polypeptide B15	approved	Tamoxifen	CC\C(=C(/C1=CC=CC=C1)C1=CC=C(OCCN(C)C)C=C1)C1=CC=CC=C1
UGT2B15	DB00842	UDP glucuronosyltransferase 2 family, polypeptide B15	approved	Oxazepam	OC1N=C(C2=CC=CC=C2)C2=C(NC1=O)C=CC(Cl)=C2
UGT2B15	DB00973	UDP glucuronosyltransferase 2 family, polypeptide B15	approved	Ezetimibe	O[C@@H](CC[C@@H]1[C@H](N(C1=O)C1=CC=C(F)C=C1)C1=CC=C(O)C=C1)C1=CC=C(F)C=C1
UGT2B15	DB00184	UDP glucuronosyltransferase 2 family, polypeptide B15	approved	Nicotine	CN1CCCC1C1=CN=CC=C1
UGT2B15	DB00313	UDP glucuronosyltransferase 2 family, polypeptide B15	approved; investigational	Valproic Acid	CCCC(CCC)C(O)=O
UGT2B15	DB00186	UDP glucuronosyltransferase 2 family, polypeptide B15	approved	Lorazepam	OC1N=C(C2=CC=CC=C2Cl)C2=C(NC1=O)C=CC(Cl)=C2
UGT2B15	DB01033	UDP glucuronosyltransferase 2 family, polypeptide B15	approved	Mercaptopurine	S=C1N=CNC2=C1NC=N2
UGT2B15	DB00563	UDP glucuronosyltransferase 2 family, polypeptide B15	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
UGT2B15	DB00890	UDP glucuronosyltransferase 2 family, polypeptide B15	approved	Dienestrol	CC=C(C(=CC)C1=CC=C(O)C=C1)C1=CC=C(O)C=C1
UGT2B15	DB00252	UDP glucuronosyltransferase 2 family, polypeptide B15	approved	Phenytoin	O=C1NC(=O)C(N1)(C1=CC=CC=C1)C1=CC=CC=C1
UGT2B17	DB00842	UDP glucuronosyltransferase 2 family, polypeptide B17	approved	Oxazepam	OC1N=C(C2=CC=CC=C2)C2=C(NC1=O)C=CC(Cl)=C2
UGT2B17	DB00783	UDP glucuronosyltransferase 2 family, polypeptide B17	approved; investigational	Estradiol	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CC[C@@H]2O
UGT2B17	DB00624	UDP glucuronosyltransferase 2 family, polypeptide B17	approved; investigational	Testosterone	C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CC[C@@H]2O
UGT2B17	DB02546	UDP glucuronosyltransferase 2 family, polypeptide B17	approved; investigational	Vorinostat	ONC(=O)CCCCCCC(=O)NC1=CC=CC=C1
UGT2B17	DB00990	UDP glucuronosyltransferase 2 family, polypeptide B17	approved; investigational	Exemestane	C[C@]12CC[C@H]3[C@@H](CC(=C)C4=CC(=O)C=C[C@]34C)[C@@H]1CCC2=O
UGT2B4	DB00318	UDP glucuronosyltransferase 2 family, polypeptide B4	illicit; approved	Codeine	COC1=C2O[C@H]3[C@@H](O)C=C[C@H]4[C@H]5CC(C=C1)=C2[C@@]34CCN5C
UGT2B4	DB00712	UDP glucuronosyltransferase 2 family, polypeptide B4	approved	Flurbiprofen	CC(C(O)=O)C1=CC(F)=C(C=C1)C1=CC=CC=C1
UGT2B4	DB01050	UDP glucuronosyltransferase 2 family, polypeptide B4	approved	Ibuprofen	CC(C)CC1=CC=C(C=C1)C(C)C(O)=O
UGT2B4	DB01009	UDP glucuronosyltransferase 2 family, polypeptide B4	approved	Ketoprofen	CC(C(O)=O)C1=CC(=CC=C1)C(=O)C1=CC=CC=C1
UGT2B7	DB00675	UDP glucuronosyltransferase 2 family, polypeptide B7	approved	Tamoxifen	CC\C(=C(/C1=CC=CC=C1)C1=CC=C(OCCN(C)C)C=C1)C1=CC=CC=C1
UGT2B7	DB01544	UDP glucuronosyltransferase 2 family, polypeptide B7	illicit; approved	Flunitrazepam	CN1C2=C(C=C(C=C2)[N+]([O-])=O)C(=NCC1=O)C1=CC=CC=C1F
UGT2B7	DB00317	UDP glucuronosyltransferase 2 family, polypeptide B7	approved; investigational	Gefitinib	COC1=C(OCCCN2CCOCC2)C=C2C(NC3=CC(Cl)=C(F)C=C3)=NC=NC2=C1
UGT2B7	DB00184	UDP glucuronosyltransferase 2 family, polypeptide B7	approved	Nicotine	CN1CCCC1C1=CN=CC=C1
UGT2B7	DB00318	UDP glucuronosyltransferase 2 family, polypeptide B7	illicit; approved	Codeine	COC1=C2O[C@H]3[C@@H](O)C=C[C@H]4[C@H]5CC(C=C1)=C2[C@@]34CCN5C
UGT2B7	DB00495	UDP glucuronosyltransferase 2 family, polypeptide B7	approved	Zidovudine	CC1=CN([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2)C(=O)NC1=O
UGT2B7	DB00678	UDP glucuronosyltransferase 2 family, polypeptide B7	approved	Losartan	CCCCC1=NC(Cl)=C(CO)N1CC1=CC=C(C=C1)C1=CC=CC=C1C1=NNN=N1
UGT2B7	DB00564	UDP glucuronosyltransferase 2 family, polypeptide B7	approved; investigational	Carbamazepine	NC(=O)N1C2=CC=CC=C2C=CC2=CC=CC=C12
UGT2B7	DB00445	UDP glucuronosyltransferase 2 family, polypeptide B7	approved	Epirubicin	COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3O[C@H]3C[C@H](N)[C@@H](O)[C@H](C)O3)C(=O)CO)C(O)=C1C2=O
UGT2B7	DB00333	UDP glucuronosyltransferase 2 family, polypeptide B7	approved	Methadone	CCC(=O)C(CC(C)N(C)C)(C1=CC=CC=C1)C1=CC=CC=C1
UGT2B7	DB00683	UDP glucuronosyltransferase 2 family, polypeptide B7	illicit; approved	Midazolam	CC1=NC=C2CN=C(C3=CC=CC=C3F)C3=C(C=CC(Cl)=C3)N12
UGT2B7	DB00186	UDP glucuronosyltransferase 2 family, polypeptide B7	approved	Lorazepam	OC1N=C(C2=CC=CC=C2Cl)C2=C(NC1=O)C=CC(Cl)=C2
UGT2B7	DB00313	UDP glucuronosyltransferase 2 family, polypeptide B7	approved; investigational	Valproic Acid	CCCC(CCC)C(O)=O
UGT2B7	DB00295	UDP glucuronosyltransferase 2 family, polypeptide B7	approved; investigational	Morphine	CN1CC[C@]23[C@H]4OC5=C(O)C=CC(C[C@@H]1[C@@H]2C=C[C@@H]4O)=C35
UGT2B7	DB00586	UDP glucuronosyltransferase 2 family, polypeptide B7	approved	Diclofenac	OC(=O)CC1=CC=CC=C1NC1=C(Cl)C=CC=C1Cl
UGT2B7	DB00688	UDP glucuronosyltransferase 2 family, polypeptide B7	approved; investigational	Mycophenolate mofetil	COC1=C(C\C=C(/C)CCC(=O)OCCN2CCOCC2)C(O)=C2C(=O)OCC2=C1C
UGT2B7	DB00921	UDP glucuronosyltransferase 2 family, polypeptide B7	illicit; approved; investigational	Buprenorphine	CO[C@]12CC[C@@]3(C[C@@H]1[C@](C)(O)C(C)(C)C)[C@H]1CC4=C5C(O[C@@H]2[C@@]35CCN1CC1CC1)=C(O)C=C4
UGT2B7	DB00446	UDP glucuronosyltransferase 2 family, polypeptide B7	approved	Chloramphenicol	OCC(NC(=O)C(Cl)Cl)C(O)C1=CC=C(C=C1)[N+]([O-])=O
UGT2B7	DB00842	UDP glucuronosyltransferase 2 family, polypeptide B7	approved	Oxazepam	OC1N=C(C2=CC=CC=C2)C2=C(NC1=O)C=CC(Cl)=C2
UGT2B7	DB00497	UDP glucuronosyltransferase 2 family, polypeptide B7	illicit; approved; investigational	Oxycodone	COC1=C2O[C@H]3C(=O)CC[C@@]4(O)[C@H]5CC(C=C1)=C2[C@@]34CCN5C
UGT2B7	DB00231	UDP glucuronosyltransferase 2 family, polypeptide B7	approved	Temazepam	CN1C2=C(C=C(Cl)C=C2)C(=NC(O)C1=O)C1=CC=CC=C1
UGT2B7	DB01273	UDP glucuronosyltransferase 2 family, polypeptide B7	approved; investigational	Varenicline	C1[C@H]2CNC[C@@H]1C1=CC3=NC=CN=C3C=C21
UGT2B7	DB01024	UDP glucuronosyltransferase 2 family, polypeptide B7	approved	Mycophenolic acid	COC1=C(C\C=C(/C)CCC(O)=O)C(O)=C2C(=O)OCC2=C1C
UGT2B7	DB06697	UDP glucuronosyltransferase 2 family, polypeptide B7	approved	Artemether	COC1OC2OC3(C)CCC4C(C)CCC(C1C)C24OO3
UGT2B7	DB00625	UDP glucuronosyltransferase 2 family, polypeptide B7	approved; investigational	Efavirenz	FC(F)(F)[C@]1(OC(=O)NC2=C1C=C(Cl)C=C2)C#CC1CC1
UGT2B7	DB00712	UDP glucuronosyltransferase 2 family, polypeptide B7	approved	Flurbiprofen	CC(C(O)=O)C1=CC(F)=C(C=C1)C1=CC=CC=C1
UGT2B7	DB01050	UDP glucuronosyltransferase 2 family, polypeptide B7	approved	Ibuprofen	CC(C)CC1=CC=C(C=C1)C(C)C(O)=O
UGT2B7	DB01009	UDP glucuronosyltransferase 2 family, polypeptide B7	approved	Ketoprofen	CC(C(O)=O)C1=CC(=CC=C1)C(=O)C1=CC=CC=C1
UMPS	DB00515	uridine monophosphate synthetase	approved	Cisplatin	N[Pt](N)(Cl)Cl
UMPS	DB00544	uridine monophosphate synthetase	approved	Fluorouracil	FC1=CNC(=O)NC1=O
UMPS	DB00526	uridine monophosphate synthetase	approved; investigational	Oxaliplatin	O=C1O[Pt]2(N[C@@H]3CCCC[C@H]3N2)OC1=O
UMPS	DB00130	uridine monophosphate synthetase	approved; nutraceutical; investigational	L-Glutamine	N[C@@H](CCC(N)=O)C(O)=O
UMPS	DB00650	uridine monophosphate synthetase	approved	Leucovorin	NC1=NC(=O)C2=C(NCC(CNC3=CC=C(C=C3)C(=O)N[C@H](CCC(O)=O)C(O)=O)N2C=O)N1
UPB1	DB01101	ureidopropionase, beta	approved; investigational	Capecitabine	CCCCCOC(=O)NC1=NC(=O)N(C=C1F)[C@@H]1O[C@H](C)[C@@H](O)[C@H]1O
UPB1	DB00544	ureidopropionase, beta	approved	Fluorouracil	FC1=CNC(=O)NC1=O
UPP1	DB07437	uridine phosphorylase 1	experimental	1-((2-HYDROXYETHOXY)METHYL)-5-BENZYLPYRIMIDINE-2,4(1H,3H)-DIONE	OCCOCN1C=C(CC2=CC=CC=C2)C(=O)NC1=O
UPP1	DB01101	uridine phosphorylase 1	approved; investigational	Capecitabine	CCCCCOC(=O)NC1=NC(=O)N(C=C1F)[C@@H]1O[C@H](C)[C@@H](O)[C@H]1O
UPP1	DB00544	uridine phosphorylase 1	approved	Fluorouracil	FC1=CNC(=O)NC1=O
UPP1	DB00184	uridine phosphorylase 1	approved	Nicotine	CN1CCCC1C1=CN=CC=C1
UPP1	DB02745	uridine phosphorylase 1	experimental	Uridine	OC[C@@H]1O[C@H]([C@H](O)[C@H]1O)N1C=CC(=O)NC1=O
UPP2	DB01101	uridine phosphorylase 2	approved; investigational	Capecitabine	CCCCCOC(=O)NC1=NC(=O)N(C=C1F)[C@@H]1O[C@H](C)[C@@H](O)[C@H]1O
UPP2	DB00544	uridine phosphorylase 2	approved	Fluorouracil	FC1=CNC(=O)NC1=O
UPRT	DB03685	uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae)	experimental	Uridine-5'-Monophosphate	O[C@@H]1[C@@H](O)[C@@H](O[C@H]1COP(O)(O)=O)N1C=CC(=O)NC1=O
UROC1	DB00117	urocanate hydratase 1	approved; nutraceutical	L-Histidine	N[C@@H](CC1=CN=CN1)C(O)=O
UROD	DB00145	uroporphyrinogen decarboxylase	approved; nutraceutical	Glycine	NCC(O)=O
UROS	DB00145	uroporphyrinogen III synthase	approved; nutraceutical	Glycine	NCC(O)=O
UST	DB00540	uronyl-2-sulfotransferase	approved	Nortriptyline	CNCCC=C1C2=CC=CC=C2CCC2=CC=CC=C12
VAMP2	DB00126	vesicle-associated membrane protein 2 (synaptobrevin 2)	approved; nutraceutical	Vitamin C	OC[C@H](O)[C@H]1OC(=O)C(O)=C1O
VAMP2	DB00121	vesicle-associated membrane protein 2 (synaptobrevin 2)	approved; nutraceutical	Biotin	OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12
VAMP2	DB00130	vesicle-associated membrane protein 2 (synaptobrevin 2)	approved; nutraceutical; investigational	L-Glutamine	N[C@@H](CCC(N)=O)C(O)=O
VAMP2	DB00149	vesicle-associated membrane protein 2 (synaptobrevin 2)	approved; nutraceutical	L-Leucine	CC(C)CC(N)C(O)=O
VAMP2	DB00122	vesicle-associated membrane protein 2 (synaptobrevin 2)	approved; nutraceutical	Choline	C[N+](C)(C)CCO
VAMP2	DB00988	vesicle-associated membrane protein 2 (synaptobrevin 2)	approved	Dopamine	NCCC1=CC(O)=C(O)C=C1
VDAC1	DB01375	voltage-dependent anion channel 1	approved	Dihydroxyaluminium	O.O.NCC(=O)O[Al]
VKORC1	DB00170	vitamin K epoxide reductase complex, subunit 1	approved; nutraceutical	Menadione	CC1=CC(=O)C2=CC=CC=C2C1=O
VKORC1	DB00266	vitamin K epoxide reductase complex, subunit 1	approved	Dicumarol	OC1=C(CC2=C(O)OC3=CC=CC=C3C2=O)C(=O)C2=CC=CC=C2O1
VKORC1	DB00498	vitamin K epoxide reductase complex, subunit 1	approved	Phenindione	O=C1C(C(=O)C2=CC=CC=C12)C1=CC=CC=C1
VKORC1	DB00682	vitamin K epoxide reductase complex, subunit 1	approved	Warfarin	CC(=O)CC(C1=CC=CC=C1)C1=C(O)OC2=CC=CC=C2C1=O
VKORC1	DB00946	vitamin K epoxide reductase complex, subunit 1	approved	Phenprocoumon	CCC(C1=CC=CC=C1)C1=C(O)OC2=CC=CC=C2C1=O
VKORC1	DB01418	vitamin K epoxide reductase complex, subunit 1	approved	Acenocoumarol	CC(=O)CC(C1=CC=C(C=C1)[N+]([O-])=O)C1=C(O)OC2=CC=CC=C2C1=O
VKORC1	DB01118	vitamin K epoxide reductase complex, subunit 1	approved; investigational	Amiodarone	CCCCC1=C(C(=O)C2=CC(I)=C(OCCN(CC)CC)C(I)=C2)C2=CC=CC=C2O1
VKORC1	DB00641	vitamin K epoxide reductase complex, subunit 1	approved	Simvastatin	CCC(C)(C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CCC3C[C@@H](O)CC(=O)O3)[C@@H]12
WARS	DB00150	tryptophanyl-tRNA synthetase	approved; nutraceutical	L-Tryptophan	N[C@@H](CC1=CNC2=CC=CC=C12)C(O)=O
WARS	DB01831	tryptophanyl-tRNA synthetase	experimental	Tryptophanyl-5'amp	N[C@@H](CC1=CNC2=CC=CC=C12)C(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC2=C(N)N=CN=C12
WARS	DB04537	tryptophanyl-tRNA synthetase	experimental	L-Tryptophanamide	N[C@@H](CC1=CNC2=C1C=CC=C2)C(N)=O
WARS	DB00145	tryptophanyl-tRNA synthetase	approved; nutraceutical	Glycine	NCC(O)=O
WARS	DB00160	tryptophanyl-tRNA synthetase	approved; nutraceutical	L-Alanine	C[C@H](N)C(O)=O
WARS	DB00125	tryptophanyl-tRNA synthetase	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
WARS	DB00151	tryptophanyl-tRNA synthetase	approved; nutraceutical	L-Cysteine	N[C@@H](CS)C(O)=O
WARS	DB00130	tryptophanyl-tRNA synthetase	approved; nutraceutical; investigational	L-Glutamine	N[C@@H](CCC(N)=O)C(O)=O
WARS	DB00117	tryptophanyl-tRNA synthetase	approved; nutraceutical	L-Histidine	N[C@@H](CC1=CN=CN1)C(O)=O
WARS	DB00149	tryptophanyl-tRNA synthetase	approved; nutraceutical	L-Leucine	CC(C)CC(N)C(O)=O
WARS	DB00123	tryptophanyl-tRNA synthetase	approved; nutraceutical	L-Lysine	NCCCC[C@H](N)C(O)=O
WARS	DB00134	tryptophanyl-tRNA synthetase	approved; nutraceutical	L-Methionine	CSCC[C@H](N)C(O)=O
WARS	DB00120	tryptophanyl-tRNA synthetase	approved; nutraceutical	L-Phenylalanine	N[C@@H](CC1=CC=CC=C1)C(O)=O
WARS	DB00172	tryptophanyl-tRNA synthetase	approved; nutraceutical	L-Proline	OC(=O)[C@@H]1CCCN1
WARS	DB00133	tryptophanyl-tRNA synthetase	approved; nutraceutical	L-Serine	N[C@@H](CO)C(O)=O
WARS	DB00156	tryptophanyl-tRNA synthetase	approved; nutraceutical	L-Threonine	C[C@@H](O)[C@H](N)C(O)=O
WARS	DB00135	tryptophanyl-tRNA synthetase	approved; nutraceutical	L-Tyrosine	N[C@@H](CC1=CC=C(O)C=C1)C(O)=O
WARS	DB00161	tryptophanyl-tRNA synthetase	approved; nutraceutical	L-Valine	CC(C)[C@H](N)C(O)=O
WARS2	DB00150	tryptophanyl tRNA synthetase 2, mitochondrial	approved; nutraceutical	L-Tryptophan	N[C@@H](CC1=CNC2=CC=CC=C12)C(O)=O
WARS2	DB00145	tryptophanyl tRNA synthetase 2, mitochondrial	approved; nutraceutical	Glycine	NCC(O)=O
WARS2	DB00160	tryptophanyl tRNA synthetase 2, mitochondrial	approved; nutraceutical	L-Alanine	C[C@H](N)C(O)=O
WARS2	DB00125	tryptophanyl tRNA synthetase 2, mitochondrial	approved; nutraceutical	L-Arginine	N[C@@H](CCCNC(N)=N)C(O)=O
WARS2	DB00151	tryptophanyl tRNA synthetase 2, mitochondrial	approved; nutraceutical	L-Cysteine	N[C@@H](CS)C(O)=O
WARS2	DB00130	tryptophanyl tRNA synthetase 2, mitochondrial	approved; nutraceutical; investigational	L-Glutamine	N[C@@H](CCC(N)=O)C(O)=O
WARS2	DB00117	tryptophanyl tRNA synthetase 2, mitochondrial	approved; nutraceutical	L-Histidine	N[C@@H](CC1=CN=CN1)C(O)=O
WARS2	DB00149	tryptophanyl tRNA synthetase 2, mitochondrial	approved; nutraceutical	L-Leucine	CC(C)CC(N)C(O)=O
WARS2	DB00123	tryptophanyl tRNA synthetase 2, mitochondrial	approved; nutraceutical	L-Lysine	NCCCC[C@H](N)C(O)=O
WARS2	DB00134	tryptophanyl tRNA synthetase 2, mitochondrial	approved; nutraceutical	L-Methionine	CSCC[C@H](N)C(O)=O
WARS2	DB00120	tryptophanyl tRNA synthetase 2, mitochondrial	approved; nutraceutical	L-Phenylalanine	N[C@@H](CC1=CC=CC=C1)C(O)=O
WARS2	DB00133	tryptophanyl tRNA synthetase 2, mitochondrial	approved; nutraceutical	L-Serine	N[C@@H](CO)C(O)=O
WARS2	DB00156	tryptophanyl tRNA synthetase 2, mitochondrial	approved; nutraceutical	L-Threonine	C[C@@H](O)[C@H](N)C(O)=O
WARS2	DB00135	tryptophanyl tRNA synthetase 2, mitochondrial	approved; nutraceutical	L-Tyrosine	N[C@@H](CC1=CC=C(O)C=C1)C(O)=O
WARS2	DB00161	tryptophanyl tRNA synthetase 2, mitochondrial	approved; nutraceutical	L-Valine	CC(C)[C@H](N)C(O)=O
XDH	DB00437	xanthine dehydrogenase	approved	Allopurinol	O=C1N=CN=C2NNC=C12
XDH	DB00583	xanthine dehydrogenase	approved	L-Carnitine	C[N+](C)(C)C[C@H](O)CC([O-])=O
XDH	DB01685	xanthine dehydrogenase	experimental	4-[5-Pyridin-4-Yl-1h-[1,2,4]Triazol-3-Yl]-Pyridine-2-Carbonitrile	N#CC1=NC=CC(=C1)C1=NNC(=N1)C1=CC=NC=C1
XDH	DB03147	xanthine dehydrogenase	experimental	Flavin-Adenine Dinucleotide	CC1=CC2=C(C=C1C)N(C[C@H](O)[C@H](O)[C@H](O)CO[P@](O)(=O)O[P@@](O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1C=NC3=C1N=CN=C3N)C1=NC(=O)NC(=O)C1=N2
XDH	DB03328	xanthine dehydrogenase	experimental	dioxothiomolybdenum(VI) ion	S[Mo](=O)=O
XDH	DB03841	xanthine dehydrogenase	experimental	Y-700	CC(C)(C)COC1=C(C=C(C=C1)N1C=C(C=N1)C(O)=O)C#N
XDH	DB00997	xanthine dehydrogenase	approved; investigational	Doxorubicin	COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3O[C@H]3C[C@H](N)[C@H](O)[C@H](C)O3)C(=O)CO)C(O)=C1C2=O
XDH	DB00277	xanthine dehydrogenase	approved	Theophylline	CN1C2=C(NC=N2)C(=O)N(C)C1=O
XDH	DB00898	xanthine dehydrogenase	approved	Ethanol	CCO
XDH	DB01412	xanthine dehydrogenase	approved	Theobromine	CN1C=NC2=C1C(=O)NC(=O)N2C
XDH	DB00993	xanthine dehydrogenase	approved	Azathioprine	CN1C=NC(=C1SC1=NC=NC2=C1NC=N2)[N+]([O-])=O
XDH	DB00170	xanthine dehydrogenase	approved; nutraceutical	Menadione	CC1=CC(=O)C2=CC=CC=C2C1=O
XDH	DB00563	xanthine dehydrogenase	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
XDH	DB00201	xanthine dehydrogenase	approved	Caffeine	CN1C=NC2=C1C(=O)N(C)C(=O)N2C
XDH	DB01033	xanthine dehydrogenase	approved	Mercaptopurine	S=C1N=CNC2=C1NC=N2
XDH	DB00339	xanthine dehydrogenase	approved	Pyrazinamide	NC(=O)C1=NC=CN=C1
XPO1	DB00171	exportin 1 (CRM1 homolog, yeast)	approved; nutraceutical	Adenosine triphosphate	NC1=C2N=CN([C@@H]3O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
XPO1	DB00864	exportin 1 (CRM1 homolog, yeast)	approved; investigational	Tacrolimus	CO[C@@H]1C[C@@H](CC[C@H]1O)\C=C(/C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H]([C@H](C[C@H]2C)OC)[C@H](C[C@@H](C)C\C(C)=C\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]1C)OC
CYC1	DB04141	cytochrome c-1	experimental	2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol	CCCCCCO[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O
CYC1	DB04799	cytochrome c-1	experimental	5-n-undecyl-6-hydroxy-4,7-dioxobenzothiazole	CCCCCCCCCCCC1=C(O)C(=O)C2=C(N=CS2)C1=O
CYC1	DB07401	cytochrome c-1	experimental	METHYL (2Z)-2-(2-{[6-(2-CYANOPHENOXY)PYRIMIDIN-4-YL]OXY}PHENYL)-3-METHOXYACRYLATE	CO\C=C(\C(=O)OC)C1=CC=CC=C1OC1=NC=NC(OC2=CC=CC=C2C#N)=C1
CYC1	DB07636	cytochrome c-1	experimental	5-HEPTYL-6-HYDROXY-1,3-BENZOTHIAZOLE-4,7-DIONE	CCCCCCCC1=C(O)C(=O)C2=C(N=CS2)C1=O
CYC1	DB07763	cytochrome c-1	experimental	(5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE	C[C@]1(OC(=O)N(NC2=CC=CC=C2)C1=O)C1=CC=C(F)C=C1F
CYC1	DB07778	cytochrome c-1	experimental	FAMOXADONE	C[C@]1(OC(=O)N(NC2=CC=CC=C2)C1=O)C1=CC=C(OC2=CC=CC=C2)C=C1
CYC1	DB08330	cytochrome c-1	experimental	METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE	CO\C=C(\C(=O)OC)C1=C(\C=C\C2=CC=CC=C2)C=CC=C1
CYC1	DB08453	cytochrome c-1	experimental	2-NONYL-4-HYDROXYQUINOLINE N-OXIDE	CCCCCCCCCC1=[N+]([O-])C2=CC=CC=C2C(O)=C1
CYC1	DB08690	cytochrome c-1	experimental	UBIQUINONE-2	COC1=C(OC)C(=O)C(C\C=C(/C)CCC=C(C)C)=C(C)C1=O
TP53	DB01008	tumor protein p53	approved; investigational	Busulfan	CS(=O)(=O)OCCCCOS(C)(=O)=O
TP53	DB00675	tumor protein p53	approved	Tamoxifen	CC\C(=C(/C1=CC=CC=C1)C1=CC=C(OCCN(C)C)C=C1)C1=CC=CC=C1
TP53	DB00269	tumor protein p53	approved	Chlorotrianisene	COC1=CC=C(C=C1)C(Cl)=C(C1=CC=C(OC)C=C1)C1=CC=C(OC)C=C1
TP53	DB00286	tumor protein p53	approved	Conjugated Estrogens	[Na+].C[C@]12CC[C@H]3[C@@H](CCC4=CC(OS([O-])(=O)=O)=CC=C34)[C@@H]1CCC2=O
TP53	DB00890	tumor protein p53	approved	Dienestrol	CC=C(C(=CC)C1=CC=C(O)C=C1)C1=CC=C(O)C=C1
TP53	DB00255	tumor protein p53	approved	Diethylstilbestrol	CCC(=C(CC)C1=CC=C(O)C=C1)C1=CC=C(O)C=C1
TP53	DB00783	tumor protein p53	approved; investigational	Estradiol	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CC[C@@H]2O
TP53	DB00655	tumor protein p53	approved	Estrone	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CCC2=O
TP53	DB00977	tumor protein p53	approved	Ethinyl Estradiol	C[C@]12CC[C@H]3[C@@H](CCC4=C3C=CC(O)=C4)[C@@H]1CC[C@@]2(O)C#C
TP53	DB00958	tumor protein p53	approved	Carboplatin	N.N.O=C1O[Pt]OC(=O)C11CCC1
TP53	DB00531	tumor protein p53	approved; investigational	Cyclophosphamide	ClCCN(CCCl)P1(=O)NCCCO1
TP53	DB01248	tumor protein p53	approved; investigational	Docetaxel	CC(=O)O[C@@]12CO[C@@H]1C[C@H](O)[C@]1(C)[C@@H]2[C@H](OC(=O)C2=CC=CC=C2)[C@]2(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C3=CC=CC=C3)C(C)=C([C@@H](O)C1=O)C2(C)C
TP53	DB00997	tumor protein p53	approved; investigational	Doxorubicin	COC1=CC=CC2=C1C(=O)C1=C(O)C3=C(C[C@](O)(C[C@@H]3O[C@H]3C[C@H](N)[C@H](O)[C@H](C)O3)C(=O)CO)C(O)=C1C2=O
TP53	DB00773	tumor protein p53	approved	Etoposide	COC1=CC(=CC(OC)=C1O)[C@H]1[C@@H]2[C@H](COC2=O)[C@H](O[C@@H]2O[C@@H]3CO[C@@H](C)O[C@H]3[C@H](O)[C@H]2O)C2=CC3=C(OCO3)C=C12
TP53	DB00544	tumor protein p53	approved	Fluorouracil	FC1=CNC(=O)NC1=O
TP53	DB01229	tumor protein p53	approved	Paclitaxel	CC(=O)O[C@@H]1C2=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)C3=CC=CC=C3)[C@@H]3[C@@]4(CO[C@@H]4C[C@H](O)[C@@]3(C)C1=O)OC(C)=O)C2(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)C1=CC=CC=C1)C1=CC=CC=C1
TP53	DB01030	tumor protein p53	approved; investigational	Topotecan	CC[C@@]1(O)C(=O)OCC2=C1C=C1N(CC3=CC4=C(C=CC(O)=C4CN(C)C)N=C13)C2=O
TP53	DB00515	tumor protein p53	approved	Cisplatin	N[Pt](N)(Cl)Cl
TP53	DB01033	tumor protein p53	approved	Mercaptopurine	S=C1N=CNC2=C1NC=N2
TP53	DB00563	tumor protein p53	approved	Methotrexate	CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
TP53	DB01050	tumor protein p53	approved	Ibuprofen	CC(C)CC1=CC=C(C=C1)C(C)C(O)=O
TP53	DB00291	tumor protein p53	approved	Chlorambucil	OC(=O)CCCC1=CC=C(C=C1)N(CCCl)CCCl