Gene Page: KLLN
Summary ?
| GeneID | 100144748 |
| Symbol | KLLN |
| Synonyms | CWS4|KILLIN |
| Description | killin, p53-regulated DNA replication inhibitor |
| Reference | MIM:612105|HGNC:HGNC:37212|Ensembl:ENSG00000227268|Vega:OTTHUMG00000186455 |
| Gene type | protein-coding |
| Map location | 10q23 |
| Pascal p-value | 0.017 |
| DMG | 1 (# studies) |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS | |
| DMG:Jaffe_2016 | Genome-wide DNA methylation analysis | This dataset includes 2,104 probes/CpGs associated with SZ patients (n=108) compared to 136 controls at Bonferroni-adjusted P < 0.05. | 1 |
Section I. Genetics and epigenetics annotation
Differentially methylated gene
| Probe | Chromosome | Position | Nearest gene | P (dis) | Beta (dis) | FDR (dis) | Study |
|---|---|---|---|---|---|---|---|
| cg16404460 | 10 | 89622595 | KLLN | 2.87E-10 | -0.019 | 6.62E-7 | DMG:Jaffe_2016 |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.