Gene Page: CDH15

Summary ?
GeneID1013
SymbolCDH15
SynonymsCDH14|CDH3|CDHM|MCAD|MRD3
Descriptioncadherin 15
ReferenceMIM:114019|HGNC:HGNC:1754|Ensembl:ENSG00000129910|HPRD:00225|Vega:OTTHUMG00000138045
Gene typeprotein-coding
Map location16q24.3
Pascal p-value0.002
Fetal beta-0.015
eGeneCerebellum
Myers' cis & trans
SupportCELL ADHESION AND TRANSSYNAPTIC SIGNALING

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS
PMID:cooccurHigh-throughput literature-searchSystematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included.
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: schizophrenia,schizophreniasClick to show details

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs17392743chr154764240CDH1510130.15trans
rs2502827chr1176044216CDH1510130.12trans
rs12405921chr1206695730CDH1510130.07trans
rs17572651chr1218943612CDH1510130trans
rs16829545chr2151977407CDH1510133.942E-21trans
rs16841750chr2158288461CDH1510130.15trans
rs3845734chr2171125572CDH1510131.978E-4trans
rs7584986chr2184111432CDH1510132.859E-10trans
rs2183142chr4159232695CDH1510130.02trans
rs1396222chr4173279496CDH1510130.14trans
rs335980chr4173329784CDH1510130.07trans
rs337984chr4173411662CDH1510130.15trans
rs17762315chr576807576CDH1510135.54E-4trans
rs7729096chr576835927CDH1510130.16trans
rs9461864chr633481468CDH1510130.06trans
rs3118341chr925185518CDH1510130.05trans
rs11139334chr984209393CDH1510130.01trans
rs2393316chr1059333070CDH1510130trans
rs1526959chr1279753789CDH1510130.11trans
rs16955618chr1529937543CDH1510133.157E-33trans
rs16945437chr1711797650CDH1510130.18trans
rs11873184chr181584081CDH1510130.09trans
rs1041786chr2122617710CDH1510131.155E-5trans
rs16986332chrX10958354CDH1510130.06trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
KEGG CELL ADHESION MOLECULES CAMS 13493All SZGR 2.0 genes in this pathway
REACTOME DEVELOPMENTAL BIOLOGY 396292All SZGR 2.0 genes in this pathway
REACTOME CELL CELL COMMUNICATION 12077All SZGR 2.0 genes in this pathway
REACTOME ADHERENS JUNCTIONS INTERACTIONS 2720All SZGR 2.0 genes in this pathway
REACTOME CELL CELL JUNCTION ORGANIZATION 5631All SZGR 2.0 genes in this pathway
REACTOME CELL JUNCTION ORGANIZATION 7843All SZGR 2.0 genes in this pathway
REACTOME MYOGENESIS 2820All SZGR 2.0 genes in this pathway
ZHOU INFLAMMATORY RESPONSE LIVE UP 485293All SZGR 2.0 genes in this pathway
ZHOU INFLAMMATORY RESPONSE LPS UP 431237All SZGR 2.0 genes in this pathway
LOPEZ MBD TARGETS 957597All SZGR 2.0 genes in this pathway
NIKOLSKY BREAST CANCER 16Q24 AMPLICON 5338All SZGR 2.0 genes in this pathway
JECHLINGER EPITHELIAL TO MESENCHYMAL TRANSITION UP 7151All SZGR 2.0 genes in this pathway
TARTE PLASMA CELL VS PLASMABLAST UP 398262All SZGR 2.0 genes in this pathway
REN ALVEOLAR RHABDOMYOSARCOMA UP 9864All SZGR 2.0 genes in this pathway
HU GENOTOXIC DAMAGE 24HR 3522All SZGR 2.0 genes in this pathway
IVANOVA HEMATOPOIESIS STEM CELL AND PROGENITOR 681420All SZGR 2.0 genes in this pathway
YOSHIOKA LIVER CANCER EARLY RECURRENCE DN 6531All SZGR 2.0 genes in this pathway
MIKKELSEN ES ICP WITH H3K4ME3 718401All SZGR 2.0 genes in this pathway