Gene Page: ZBTB18
Summary ?
| GeneID | 10472 |
| Symbol | ZBTB18 |
| Synonyms | C2H2-171|MRD22|RP58|TAZ-1|ZNF238 |
| Description | zinc finger and BTB domain containing 18 |
| Reference | MIM:608433|HGNC:HGNC:13030|Ensembl:ENSG00000179456|HPRD:12231|Vega:OTTHUMG00000040013 |
| Gene type | protein-coding |
| Map location | 1q44 |
| DMG | 1 (# studies) |
| eGene | Cerebellum |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS | |
| DMG:Jaffe_2016 | Genome-wide DNA methylation analysis | This dataset includes 2,104 probes/CpGs associated with SZ patients (n=108) compared to 136 controls at Bonferroni-adjusted P < 0.05. | 1 |
Section I. Genetics and epigenetics annotation
Differentially methylated gene
| Probe | Chromosome | Position | Nearest gene | P (dis) | Beta (dis) | FDR (dis) | Study |
|---|---|---|---|---|---|---|---|
| cg19996838 | 1 | 244211323 | ZBTB18 | 4.14E-10 | -0.015 | 7.79E-7 | DMG:Jaffe_2016 |
eQTL annotation
| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs16829545 | chr2 | 151977407 | ZNF238 | 10472 | 5.705E-4 | trans | ||
| rs16955618 | chr15 | 29937543 | ZNF238 | 10472 | 0 | trans |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.