Gene Page: FBXW10
Summary ?
| GeneID | 10517 |
| Symbol | FBXW10 |
| Synonyms | Fbw10|HREP|SM25H2|SM2SH2 |
| Description | F-box and WD repeat domain containing 10 |
| Reference | MIM:611679|HGNC:HGNC:1211|Ensembl:ENSG00000171931|HPRD:06851|Vega:OTTHUMG00000059048 |
| Gene type | protein-coding |
| Map location | 17p12 |
| Pascal p-value | 0.004 |
| eGene | Cerebellar Hemisphere Cerebellum Cortex |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| VPRBP | 0.98 | 0.98 |
| TOP1 | 0.97 | 0.97 |
| THRAP3 | 0.97 | 0.97 |
| PHF20 | 0.97 | 0.97 |
| SIN3A | 0.96 | 0.98 |
| KHDRBS1 | 0.96 | 0.96 |
| UBE2R2 | 0.96 | 0.97 |
| KDM4A | 0.96 | 0.97 |
| ZNF512 | 0.96 | 0.96 |
| HNRNPR | 0.96 | 0.97 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| FXYD1 | -0.77 | -0.92 |
| AF347015.31 | -0.77 | -0.91 |
| MT-CO2 | -0.76 | -0.91 |
| AIFM3 | -0.75 | -0.81 |
| TSC22D4 | -0.75 | -0.84 |
| IFI27 | -0.75 | -0.90 |
| S100B | -0.75 | -0.85 |
| C5orf53 | -0.74 | -0.77 |
| HLA-F | -0.74 | -0.78 |
| AF347015.27 | -0.74 | -0.87 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| MARSON BOUND BY FOXP3 STIMULATED | 1022 | 619 | All SZGR 2.0 genes in this pathway |
| MARSON BOUND BY FOXP3 UNSTIMULATED | 1229 | 713 | All SZGR 2.0 genes in this pathway |
| MIKKELSEN MEF LCP WITH H3K4ME3 | 128 | 68 | All SZGR 2.0 genes in this pathway |
| MIKKELSEN IPS LCP WITH H3K4ME3 | 174 | 100 | All SZGR 2.0 genes in this pathway |
| MIKKELSEN ES LCP WITH H3K4ME3 | 142 | 80 | All SZGR 2.0 genes in this pathway |
| PURBEY TARGETS OF CTBP1 NOT SATB1 DN | 448 | 282 | All SZGR 2.0 genes in this pathway |
| FORTSCHEGGER PHF8 TARGETS UP | 279 | 155 | All SZGR 2.0 genes in this pathway |
| RAO BOUND BY SALL4 ISOFORM B | 517 | 302 | All SZGR 2.0 genes in this pathway |
| BOSCO EPITHELIAL DIFFERENTIATION MODULE | 69 | 31 | All SZGR 2.0 genes in this pathway |
| ZWANG TRANSIENTLY UP BY 1ST EGF PULSE ONLY | 1839 | 928 | All SZGR 2.0 genes in this pathway |