Summary ?
GeneID10548
SymbolTM9SF1
SynonymsHMP70|MP70
Descriptiontransmembrane 9 superfamily member 1
ReferenceHGNC:HGNC:11864|Ensembl:ENSG00000100926|HPRD:09987|Vega:OTTHUMG00000029322
Gene typeprotein-coding
Map location14q11.2
Pascal p-value0.108
Sherlock p-value1.106E-5
Fetal beta0.045

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS
GSMA_IGenome scan meta-analysisPsr: 0.047 

Section I. Genetics and epigenetics annotation


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
GenePearson's Correlation Spearman's Correlation
EXOSC70.890.89
TMED90.890.89
BAX0.870.90
TIMM440.870.88
PRPF310.860.87
CD2BP20.860.86
SAP30BP0.860.87
RALY0.860.90
PUF600.860.89
PAF10.860.86
Top 10 negatively co-expressed genes
GenePearson's Correlation Spearman's Correlation
AF347015.27-0.77-0.82
MT-CO2-0.76-0.79
AF347015.31-0.75-0.79
AF347015.33-0.74-0.79
AF347015.8-0.74-0.79
MT-CYB-0.74-0.79
AF347015.15-0.71-0.80
AF347015.2-0.71-0.79
AF347015.21-0.69-0.75
AF347015.26-0.68-0.78

Section III. Gene Ontology annotation

Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0016020membraneIEA-
GO:0016021integral to membraneIEA-
GO:0016021integral to membraneTAS9332367 

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
DIAZ CHRONIC MEYLOGENOUS LEUKEMIA UP 1382904All SZGR 2.0 genes in this pathway
SCHAEFFER PROSTATE DEVELOPMENT 6HR DN 514330All SZGR 2.0 genes in this pathway
FLECHNER BIOPSY KIDNEY TRANSPLANT OK VS DONOR UP 555346All SZGR 2.0 genes in this pathway
KAAB FAILED HEART ATRIUM DN 14199All SZGR 2.0 genes in this pathway
IVANOVA HEMATOPOIESIS LATE PROGENITOR 544307All SZGR 2.0 genes in this pathway
WELCSH BRCA1 TARGETS UP 198132All SZGR 2.0 genes in this pathway
GRADE COLON AND RECTAL CANCER DN 10165All SZGR 2.0 genes in this pathway
MILI PSEUDOPODIA CHEMOTAXIS DN 457302All SZGR 2.0 genes in this pathway
MILI PSEUDOPODIA HAPTOTAXIS DN 668419All SZGR 2.0 genes in this pathway
CHANDRAN METASTASIS DN 306191All SZGR 2.0 genes in this pathway