Gene Page: FAM114A2
Summary ?
| GeneID | 10827 |
| Symbol | FAM114A2 |
| Synonyms | 133K02|C5orf3 |
| Description | family with sequence similarity 114 member A2 |
| Reference | HGNC:HGNC:1333|Ensembl:ENSG00000055147|HPRD:12831|Vega:OTTHUMG00000130147 |
| Gene type | protein-coding |
| Map location | 5q33.2 |
| Pascal p-value | 2.299E-4 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| DNMT1 | 0.96 | 0.96 |
| TRRAP | 0.96 | 0.97 |
| LIG3 | 0.96 | 0.96 |
| PLCG1 | 0.96 | 0.94 |
| PFAS | 0.96 | 0.96 |
| NUP214 | 0.96 | 0.96 |
| DHX38 | 0.96 | 0.96 |
| KIAA0892 | 0.95 | 0.95 |
| POGZ | 0.95 | 0.96 |
| KIAA1310 | 0.95 | 0.95 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| AF347015.31 | -0.76 | -0.88 |
| MT-CO2 | -0.74 | -0.88 |
| AF347015.27 | -0.73 | -0.86 |
| FXYD1 | -0.73 | -0.84 |
| AF347015.33 | -0.72 | -0.84 |
| IFI27 | -0.71 | -0.83 |
| C5orf53 | -0.71 | -0.75 |
| HIGD1B | -0.71 | -0.86 |
| S100B | -0.71 | -0.81 |
| AF347015.8 | -0.70 | -0.86 |
Section III. Gene Ontology annotation
| Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
|---|---|---|---|---|
| GO:0017076 | purine nucleotide binding | NAS | 10843801 | |
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
| GO:0008150 | biological_process | ND | - | |
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
| GO:0005575 | cellular_component | ND | - |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| RASHI RESPONSE TO IONIZING RADIATION 4 | 61 | 34 | All SZGR 2.0 genes in this pathway |
| MARTORIATI MDM4 TARGETS FETAL LIVER UP | 227 | 137 | All SZGR 2.0 genes in this pathway |
| RICKMAN TUMOR DIFFERENTIATED WELL VS POORLY DN | 382 | 224 | All SZGR 2.0 genes in this pathway |
| BYSTRYKH HEMATOPOIESIS STEM CELL AND BRAIN QTL CIS | 65 | 38 | All SZGR 2.0 genes in this pathway |
| BRUINS UVC RESPONSE LATE | 1137 | 655 | All SZGR 2.0 genes in this pathway |
| VANOEVELEN MYOGENESIS SIN3A TARGETS | 220 | 133 | All SZGR 2.0 genes in this pathway |