Gene Page: PDE10A

Summary
GeneID  10846
Symbol  PDE10A
Synonyms  FLJ11894|FLJ25677|HSPDE10A
Description  phosphodiesterase 10A
See related  HGNC:8772|MIM:610652|Ensembl:ENSG00000112541|HPRD:17828|
Locus tag  -
Gene type  protein-coding
Map location  6q26
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
TACC30.990.72
AURKB0.990.79
FAM64A0.990.78
KIF20A0.990.79
PLK10.980.78
NCAPH0.980.79
UBE2C0.980.78
HJURP0.980.79
GTSE10.980.83
NUSAP10.980.81
Top 10 negatively co-expressed genes
C5orf53-0.38-0.68
FBXO2-0.38-0.63
HLA-F-0.38-0.70
SLC9A3R2-0.37-0.41
PTH1R-0.37-0.61
ASPHD1-0.37-0.56
ALDOC-0.36-0.60
AIFM3-0.36-0.59
AF347015.27-0.36-0.73
TNFSF12-0.36-0.58
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:00041143',5'-cyclic-nucleotide phosphodiesterase activityIEA-
GO:00041143',5'-cyclic-nucleotide phosphodiesterase activityTAS10373451 
GO:0016787hydrolase activityIEA-
GO:0030553cGMP bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007165signal transductionIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005737cytoplasmIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CASP3CPP32 | CPP32B | SCA-1caspase 3, apoptosis-related cysteine peptidase-HPRD11602184 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_PURINE_METABOLISM 15996All SZGR genes in this pathway
REACTOME_SIGNALING_BY_GPCR 920449All SZGR genes in this pathway
REACTOME_GPCR_DOWNSTREAM_SIGNALING 805368All SZGR genes in this pathway
REACTOME_G_ALPHA_S_SIGNALLING_EVENTS 12182All SZGR genes in this pathway
REACTOME_CGMP_EFFECTS 1913All SZGR genes in this pathway
REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE 2519All SZGR genes in this pathway
REACTOME_PLATELET_HOMEOSTASIS 7849All SZGR genes in this pathway
REACTOME_HEMOSTASIS 466331All SZGR genes in this pathway
ONKEN_UVEAL_MELANOMA_UP 783507All SZGR genes in this pathway
SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_UP 351230All SZGR genes in this pathway
WATANABE_COLON_CANCER_MSI_VS_MSS_UP 2918All SZGR genes in this pathway
GAZDA_DIAMOND_BLACKFAN_ANEMIA_PROGENITOR_UP 3925All SZGR genes in this pathway
CORRE_MULTIPLE_MYELOMA_UP 7445All SZGR genes in this pathway
PEPPER_CHRONIC_LYMPHOCYTIC_LEUKEMIA_DN 218All SZGR genes in this pathway
KIM_WT1_TARGETS_UP 214155All SZGR genes in this pathway
KIM_WT1_TARGETS_8HR_UP 164122All SZGR genes in this pathway
DELYS_THYROID_CANCER_DN 232154All SZGR genes in this pathway
GAUSSMANN_MLL_AF4_FUSION_TARGETS_E_UP 9760All SZGR genes in this pathway
PEREZ_TP53_TARGETS 1174695All SZGR genes in this pathway
SILIGAN_BOUND_BY_EWS_FLT1_FUSION 4734All SZGR genes in this pathway
BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP 811508All SZGR genes in this pathway
BENPORATH_EED_TARGETS 1062725All SZGR genes in this pathway
BENPORATH_ES_WITH_H3K27ME3 1118744All SZGR genes in this pathway
KANG_IMMORTALIZED_BY_TERT_DN 10267All SZGR genes in this pathway
CUI_TCF21_TARGETS_2_DN 830547All SZGR genes in this pathway
CUI_TCF21_TARGETS_DN 3123All SZGR genes in this pathway
YEGNASUBRAMANIAN_PROSTATE_CANCER 12860All SZGR genes in this pathway
RIGGINS_TAMOXIFEN_RESISTANCE_DN 220147All SZGR genes in this pathway
NAKAMURA_METASTASIS 4728All SZGR genes in this pathway
NAKAMURA_METASTASIS_MODEL_UP 4526All SZGR genes in this pathway
HAN_SATB1_TARGETS_UP 395249All SZGR genes in this pathway
HAN_SATB1_TARGETS_DN 442275All SZGR genes in this pathway
MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3 1069729All SZGR genes in this pathway
NAKAMURA_ADIPOGENESIS_EARLY_UP 6644All SZGR genes in this pathway
NAKAMURA_ADIPOGENESIS_LATE_UP 10467All SZGR genes in this pathway
VERHAAK_GLIOBLASTOMA_PRONEURAL 177132All SZGR genes in this pathway
PHONG_TNF_RESPONSE_NOT_VIA_P38 337236All SZGR genes in this pathway


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