Gene Page: GPR75
Summary ?
GeneID | 10936 |
Symbol | GPR75 |
Synonyms | GPRchr2|WI31133 |
Description | G protein-coupled receptor 75 |
Reference | MIM:606704|HGNC:HGNC:4526|Ensembl:ENSG00000119737|HPRD:09462|Vega:OTTHUMG00000129280 |
Gene type | protein-coding |
Map location | 2p16 |
Pascal p-value | 3.366E-4 |
eGene | Meta |
Gene in Data Sources
Gene set name | Method of gene set | Description | Info |
---|---|---|---|
CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
Top 10 positively co-expressed genes | ||
Gene | Pearson's Correlation | Spearman's Correlation |
CACNG3 | 0.92 | 0.81 |
KCNJ4 | 0.89 | 0.77 |
FMNL1 | 0.88 | 0.84 |
PRRT1 | 0.88 | 0.92 |
GRASP | 0.88 | 0.84 |
FAM131A | 0.88 | 0.81 |
CX3CL1 | 0.88 | 0.89 |
DDN | 0.87 | 0.89 |
CHRM1 | 0.87 | 0.81 |
SLC30A3 | 0.87 | 0.81 |
Top 10 negatively co-expressed genes | ||
Gene | Pearson's Correlation | Spearman's Correlation |
RPL23A | -0.52 | -0.64 |
DYNLT1 | -0.51 | -0.66 |
BCL7C | -0.51 | -0.62 |
KIAA1949 | -0.51 | -0.44 |
RBMX2 | -0.51 | -0.61 |
TIGD1 | -0.50 | -0.48 |
TUBB2B | -0.50 | -0.54 |
TRAF4 | -0.50 | -0.59 |
GPR125 | -0.50 | -0.49 |
EXOSC8 | -0.50 | -0.55 |
Section V. Pathway annotation
Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
---|---|---|---|
JAZAG TGFB1 SIGNALING UP | 108 | 69 | All SZGR 2.0 genes in this pathway |
SHEN SMARCA2 TARGETS DN | 357 | 212 | All SZGR 2.0 genes in this pathway |
ZWANG TRANSIENTLY UP BY 1ST EGF PULSE ONLY | 1839 | 928 | All SZGR 2.0 genes in this pathway |