Summary ?
GeneID10945
SymbolKDELR1
SynonymsERD2|ERD2.1|HDEL|PM23
DescriptionKDEL endoplasmic reticulum protein retention receptor 1
ReferenceMIM:131235|HGNC:HGNC:6304|Ensembl:ENSG00000105438|HPRD:00569|Vega:OTTHUMG00000183215
Gene typeprotein-coding
Map location19q13.3
Pascal p-value0.319
Sherlock p-value1.106E-6
Fetal beta0.787

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS

Section I. Genetics and epigenetics annotation


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
GenePearson's Correlation Spearman's Correlation
ZNF30.900.83
SAAL10.900.85
NUP1070.890.85
ZBED50.890.86
AC106037.20.890.87
ZNF200.890.83
PRIM10.890.84
IFT810.890.81
WTAP0.890.82
SNRPF0.890.87
Top 10 negatively co-expressed genes
GenePearson's Correlation Spearman's Correlation
HLA-F-0.67-0.72
FBXO2-0.65-0.70
PTH1R-0.65-0.72
TINAGL1-0.64-0.74
AF347015.27-0.64-0.73
ATP10A-0.63-0.74
AIFM3-0.63-0.69
AF347015.33-0.62-0.73
MT-CO2-0.61-0.71
LDHD-0.61-0.66

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
KEGG VIBRIO CHOLERAE INFECTION 5632All SZGR 2.0 genes in this pathway
BIOCARTA ARAP PATHWAY 1813All SZGR 2.0 genes in this pathway
PID ARF 3PATHWAY 1913All SZGR 2.0 genes in this pathway
GARY CD5 TARGETS UP 473314All SZGR 2.0 genes in this pathway
TIEN INTESTINE PROBIOTICS 2HR UP 2719All SZGR 2.0 genes in this pathway
TIEN INTESTINE PROBIOTICS 24HR DN 214133All SZGR 2.0 genes in this pathway
GRAESSMANN APOPTOSIS BY DOXORUBICIN DN 17811082All SZGR 2.0 genes in this pathway
LI AMPLIFIED IN LUNG CANCER 178108All SZGR 2.0 genes in this pathway
LOPEZ MBD TARGETS 957597All SZGR 2.0 genes in this pathway
PASQUALUCCI LYMPHOMA BY GC STAGE UP 283177All SZGR 2.0 genes in this pathway
TARTE PLASMA CELL VS B LYMPHOCYTE UP 7851All SZGR 2.0 genes in this pathway
BYSTRYKH HEMATOPOIESIS STEM CELL QTL TRANS 882572All SZGR 2.0 genes in this pathway
HOEGERKORP CD44 TARGETS TEMPORAL UP 138All SZGR 2.0 genes in this pathway
JIANG VHL TARGETS 13891All SZGR 2.0 genes in this pathway
IVANOVA HEMATOPOIESIS STEM CELL AND PROGENITOR 681420All SZGR 2.0 genes in this pathway
PELLICCIOTTA HDAC IN ANTIGEN PRESENTATION DN 4938All SZGR 2.0 genes in this pathway
CHEN HOXA5 TARGETS 9HR DN 4117All SZGR 2.0 genes in this pathway
AGUIRRE PANCREATIC CANCER COPY NUMBER UP 298174All SZGR 2.0 genes in this pathway
SWEET LUNG CANCER KRAS UP 491316All SZGR 2.0 genes in this pathway
SWEET KRAS ONCOGENIC SIGNATURE 8956All SZGR 2.0 genes in this pathway
CAIRO HEPATOBLASTOMA CLASSES UP 605377All SZGR 2.0 genes in this pathway
BILANGES RAPAMYCIN SENSITIVE VIA TSC1 AND TSC2 7337All SZGR 2.0 genes in this pathway