Gene Page: SNRNP27
Summary ?
| GeneID | 11017 |
| Symbol | SNRNP27 |
| Synonyms | 27K|RY1 |
| Description | small nuclear ribonucleoprotein U4/U6.U5 subunit 27 |
| Reference | HGNC:HGNC:30240|Ensembl:ENSG00000124380|HPRD:15288|Vega:OTTHUMG00000152689 |
| Gene type | protein-coding |
| Map location | 2p13.3 |
| Pascal p-value | 0.025 |
| Sherlock p-value | 0.353 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| LMNB1 | 0.94 | 0.69 |
| EZH2 | 0.93 | 0.76 |
| KIF20B | 0.93 | 0.71 |
| SMARCC1 | 0.92 | 0.79 |
| RBL1 | 0.91 | 0.75 |
| CDK5RAP2 | 0.90 | 0.78 |
| KNTC1 | 0.90 | 0.65 |
| C6orf167 | 0.90 | 0.68 |
| MCM7 | 0.89 | 0.80 |
| TIMELESS | 0.89 | 0.70 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| FBXO2 | -0.59 | -0.77 |
| TNFSF12 | -0.58 | -0.76 |
| SLC9A3R2 | -0.57 | -0.54 |
| PTH1R | -0.57 | -0.71 |
| ASPHD1 | -0.57 | -0.78 |
| LHPP | -0.56 | -0.65 |
| ADAP1 | -0.56 | -0.76 |
| SHISA4 | -0.56 | -0.82 |
| TMEM54 | -0.56 | -0.75 |
| LDHD | -0.55 | -0.71 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| KEGG SPLICEOSOME | 128 | 72 | All SZGR 2.0 genes in this pathway |
| HORIUCHI WTAP TARGETS DN | 310 | 188 | All SZGR 2.0 genes in this pathway |
| KINSEY TARGETS OF EWSR1 FLII FUSION UP | 1278 | 748 | All SZGR 2.0 genes in this pathway |
| BIDUS METASTASIS UP | 214 | 134 | All SZGR 2.0 genes in this pathway |
| MCBRYAN PUBERTAL BREAST 5 6WK UP | 116 | 68 | All SZGR 2.0 genes in this pathway |
| MCBRYAN PUBERTAL BREAST 6 7WK DN | 79 | 54 | All SZGR 2.0 genes in this pathway |
| PUJANA ATM PCC NETWORK | 1442 | 892 | All SZGR 2.0 genes in this pathway |
| STARK PREFRONTAL CORTEX 22Q11 DELETION DN | 517 | 309 | All SZGR 2.0 genes in this pathway |
| BLALOCK ALZHEIMERS DISEASE DN | 1237 | 837 | All SZGR 2.0 genes in this pathway |
| KAYO CALORIE RESTRICTION MUSCLE DN | 87 | 59 | All SZGR 2.0 genes in this pathway |
| WANG CISPLATIN RESPONSE AND XPC DN | 228 | 146 | All SZGR 2.0 genes in this pathway |
| BLALOCK ALZHEIMERS DISEASE INCIPIENT DN | 165 | 106 | All SZGR 2.0 genes in this pathway |
| MARTINEZ RB1 TARGETS DN | 543 | 317 | All SZGR 2.0 genes in this pathway |
| MARTINEZ TP53 TARGETS UP | 602 | 364 | All SZGR 2.0 genes in this pathway |
| MARTINEZ RB1 AND TP53 TARGETS UP | 601 | 369 | All SZGR 2.0 genes in this pathway |
| AMBROSINI FLAVOPIRIDOL TREATMENT TP53 | 109 | 63 | All SZGR 2.0 genes in this pathway |
| KYNG WERNER SYNDROM AND NORMAL AGING DN | 225 | 124 | All SZGR 2.0 genes in this pathway |
| YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 13 | 172 | 107 | All SZGR 2.0 genes in this pathway |
| HIRSCH CELLULAR TRANSFORMATION SIGNATURE UP | 242 | 159 | All SZGR 2.0 genes in this pathway |
| HOLLEMAN VINCRISTINE RESISTANCE B ALL UP | 38 | 22 | All SZGR 2.0 genes in this pathway |
| HOLLEMAN VINCRISTINE RESISTANCE ALL UP | 27 | 16 | All SZGR 2.0 genes in this pathway |