Gene Page: GTF2A1L
Summary ?
| GeneID | 11036 |
| Symbol | GTF2A1L |
| Synonyms | ALF |
| Description | general transcription factor IIA 1 like |
| Reference | MIM:605358|HGNC:HGNC:30727|Ensembl:ENSG00000242441|HPRD:05640|Vega:OTTHUMG00000152038 |
| Gene type | protein-coding |
| Map location | 2p16.3 |
| Pascal p-value | 0.01 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| FAF2 | 0.92 | 0.92 |
| ATMIN | 0.91 | 0.92 |
| FNDC3A | 0.91 | 0.92 |
| AP1G1 | 0.91 | 0.93 |
| ANAPC1 | 0.91 | 0.91 |
| C4orf41 | 0.91 | 0.91 |
| MAP3K7 | 0.91 | 0.91 |
| UBR1 | 0.91 | 0.92 |
| USP9X | 0.91 | 0.92 |
| SAR1A | 0.90 | 0.91 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| MT-CO2 | -0.79 | -0.80 |
| AF347015.31 | -0.78 | -0.79 |
| FXYD1 | -0.77 | -0.77 |
| HIGD1B | -0.75 | -0.78 |
| AF347015.33 | -0.75 | -0.76 |
| AF347015.21 | -0.75 | -0.80 |
| AF347015.8 | -0.75 | -0.79 |
| MT-CYB | -0.74 | -0.76 |
| AF347015.27 | -0.73 | -0.75 |
| AF347015.2 | -0.72 | -0.75 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| KEGG BASAL TRANSCRIPTION FACTORS | 36 | 24 | All SZGR 2.0 genes in this pathway |
| HATADA METHYLATED IN LUNG CANCER UP | 390 | 236 | All SZGR 2.0 genes in this pathway |
| IVANOVA HEMATOPOIESIS EARLY PROGENITOR | 532 | 309 | All SZGR 2.0 genes in this pathway |
| ACEVEDO METHYLATED IN LIVER CANCER DN | 940 | 425 | All SZGR 2.0 genes in this pathway |
| WEBER METHYLATED HCP IN FIBROBLAST DN | 42 | 22 | All SZGR 2.0 genes in this pathway |
| WEBER METHYLATED HCP IN SPERM DN | 28 | 13 | All SZGR 2.0 genes in this pathway |
| MIKKELSEN MEF HCP WITH H3 UNMETHYLATED | 228 | 119 | All SZGR 2.0 genes in this pathway |