Gene Page: ZPBP
Summary ?
| GeneID | 11055 |
| Symbol | ZPBP |
| Synonyms | ZPBP1 |
| Description | zona pellucida binding protein |
| Reference | MIM:608498|HGNC:HGNC:15662|Ensembl:ENSG00000042813|HPRD:18364|Vega:OTTHUMG00000023528 |
| Gene type | protein-coding |
| Map location | 7p14.3 |
| Pascal p-value | 0.035 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| OPA1 | 0.94 | 0.95 |
| DMXL2 | 0.94 | 0.94 |
| UBR3 | 0.93 | 0.95 |
| DMXL1 | 0.93 | 0.93 |
| COL4A3BP | 0.93 | 0.94 |
| PJA2 | 0.92 | 0.95 |
| TRIM23 | 0.92 | 0.94 |
| FAM169A | 0.92 | 0.92 |
| RAB11FIP2 | 0.92 | 0.95 |
| WDR7 | 0.91 | 0.92 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| EFEMP2 | -0.51 | -0.59 |
| RAB34 | -0.51 | -0.64 |
| EIF4EBP3 | -0.50 | -0.61 |
| C1orf61 | -0.49 | -0.72 |
| GATSL3 | -0.48 | -0.57 |
| GSDMD | -0.48 | -0.58 |
| NUDT8 | -0.48 | -0.56 |
| DBI | -0.47 | -0.58 |
| C19orf36 | -0.46 | -0.57 |
| ENHO | -0.46 | -0.59 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| GAUSSMANN MLL AF4 FUSION TARGETS G UP | 238 | 135 | All SZGR 2.0 genes in this pathway |
| SHETH LIVER CANCER VS TXNIP LOSS PAM5 | 94 | 59 | All SZGR 2.0 genes in this pathway |
| BENPORATH CYCLING GENES | 648 | 385 | All SZGR 2.0 genes in this pathway |
| SU TESTIS | 76 | 53 | All SZGR 2.0 genes in this pathway |
| IVANOVA HEMATOPOIESIS STEM CELL AND PROGENITOR | 681 | 420 | All SZGR 2.0 genes in this pathway |
| MARSON BOUND BY FOXP3 UNSTIMULATED | 1229 | 713 | All SZGR 2.0 genes in this pathway |
| WEBER METHYLATED HCP IN FIBROBLAST DN | 42 | 22 | All SZGR 2.0 genes in this pathway |
| WEBER METHYLATED HCP IN SPERM DN | 28 | 13 | All SZGR 2.0 genes in this pathway |
| MATZUK SPERMATOZOA | 114 | 77 | All SZGR 2.0 genes in this pathway |
| WHITFIELD CELL CYCLE M G1 | 148 | 95 | All SZGR 2.0 genes in this pathway |
| PURBEY TARGETS OF CTBP1 NOT SATB1 DN | 448 | 282 | All SZGR 2.0 genes in this pathway |