Summary ?
GeneID11173
SymbolADAMTS7
SynonymsADAM-TS 7|ADAM-TS7|ADAMTS-7
DescriptionADAM metallopeptidase with thrombospondin type 1 motif 7
ReferenceMIM:605009|HGNC:HGNC:223|Ensembl:ENSG00000136378|HPRD:05422|Vega:OTTHUMG00000172907
Gene typeprotein-coding
Map location15q24.2
Pascal p-value5.523E-4
eGeneCerebellum

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS

Section I. Genetics and epigenetics annotation


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
GenePearson's Correlation Spearman's Correlation
EHMT20.970.97
DVL30.970.97
WHSC20.970.96
DCAF150.960.96
DAXX0.960.95
MTA10.960.96
PRPF310.960.97
RBM100.960.96
NUP620.960.96
MEN10.960.96
Top 10 negatively co-expressed genes
GenePearson's Correlation Spearman's Correlation
AF347015.31-0.81-0.92
AF347015.27-0.79-0.91
MT-CO2-0.79-0.91
AF347015.33-0.78-0.89
MT-CYB-0.76-0.89
C5orf53-0.76-0.78
AF347015.8-0.75-0.90
S100B-0.74-0.83
AF347015.15-0.73-0.88
FXYD1-0.73-0.84

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
GRAESSMANN APOPTOSIS BY DOXORUBICIN UP 1142669All SZGR 2.0 genes in this pathway
GRAESSMANN RESPONSE TO MC AND DOXORUBICIN UP 612367All SZGR 2.0 genes in this pathway
PEREZ TP53 TARGETS 1174695All SZGR 2.0 genes in this pathway
TERAMOTO OPN TARGETS CLUSTER 6 2717All SZGR 2.0 genes in this pathway
DAIRKEE TERT TARGETS DN 12479All SZGR 2.0 genes in this pathway
BONOME OVARIAN CANCER SURVIVAL SUBOPTIMAL DEBULKING 510309All SZGR 2.0 genes in this pathway
SEKI INFLAMMATORY RESPONSE LPS UP 7756All SZGR 2.0 genes in this pathway
VANTVEER BREAST CANCER ESR1 DN 240153All SZGR 2.0 genes in this pathway
ZHANG TLX TARGETS 60HR UP 293203All SZGR 2.0 genes in this pathway
MEISSNER BRAIN HCP WITH H3K4ME3 AND H3K27ME3 1069729All SZGR 2.0 genes in this pathway
NABA ECM REGULATORS 238125All SZGR 2.0 genes in this pathway
NABA MATRISOME ASSOCIATED 753411All SZGR 2.0 genes in this pathway
NABA MATRISOME 1028559All SZGR 2.0 genes in this pathway