Summary ?
GeneID130502
SymbolTTC32
Synonyms-
Descriptiontetratricopeptide repeat domain 32
ReferenceHGNC:HGNC:32954|Ensembl:ENSG00000183891|HPRD:17296|Vega:OTTHUMG00000151776
Gene typeprotein-coding
Map location2p24.1
Pascal p-value0.211
Fetal beta0.109
DMG1 (# studies)
eGeneAnterior cingulate cortex BA24
Caudate basal ganglia
Cerebellar Hemisphere
Cerebellum
Cortex
Frontal Cortex BA9
Hippocampus
Hypothalamus
Nucleus accumbens basal ganglia
Putamen basal ganglia
Meta

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS
DMG:Jaffe_2016Genome-wide DNA methylation analysisThis dataset includes 2,104 probes/CpGs associated with SZ patients (n=108) compared to 136 controls at Bonferroni-adjusted P < 0.05. 1

Section I. Genetics and epigenetics annotation

@Differentially methylated gene

ProbeChromosomePositionNearest geneP (dis)Beta (dis)FDR (dis)Study
cg00745248220101788TTC329.56E-9-0.014.24E-6DMG:Jaffe_2016

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs62109397220082172TTC32ENSG00000183891.52.853E-14019575gtex_brain_ba24
rs62109398220082748TTC32ENSG00000183891.53.115E-14018999gtex_brain_ba24
rs13421472220082812TTC32ENSG00000183891.53.115E-14018935gtex_brain_ba24
rs62109399220083373TTC32ENSG00000183891.53.115E-14018374gtex_brain_ba24
rs7423003220083421TTC32ENSG00000183891.51.031E-7018326gtex_brain_ba24
rs10204428220084133TTC32ENSG00000183891.53.418E-8017614gtex_brain_ba24
rs10168217220084387TTC32ENSG00000183891.55.743E-7017360gtex_brain_ba24
rs12622453220084639TTC32ENSG00000183891.53.042E-7017108gtex_brain_ba24
rs10171948220085769TTC32ENSG00000183891.59.564E-8015978gtex_brain_ba24
rs13419597220086391TTC32ENSG00000183891.53.809E-7015356gtex_brain_ba24
rs13432782220086462TTC32ENSG00000183891.51.003E-7015285gtex_brain_ba24
rs12617761220088018TTC32ENSG00000183891.53.3E-15013729gtex_brain_ba24
rs10211008220088403TTC32ENSG00000183891.52.996E-8013344gtex_brain_ba24
rs80296077220089000TTC32ENSG00000183891.57.719E-16012747gtex_brain_ba24
rs13385093220089411TTC32ENSG00000183891.56.89E-7012336gtex_brain_ba24
rs35957485220090677TTC32ENSG00000183891.55.877E-17011070gtex_brain_ba24
rs16987206220090739TTC32ENSG00000183891.51.77E-7011008gtex_brain_ba24
rs11887799220091399TTC32ENSG00000183891.51.77E-7010348gtex_brain_ba24
rs11888045220091890TTC32ENSG00000183891.56.129E-1709857gtex_brain_ba24
rs11889206220092032TTC32ENSG00000183891.56.167E-1709715gtex_brain_ba24
rs7563410220096936TTC32ENSG00000183891.56.973E-1704811gtex_brain_ba24
rs12328613220097874TTC32ENSG00000183891.51.77E-703873gtex_brain_ba24
rs7572167220100988TTC32ENSG00000183891.59.742E-170759gtex_brain_ba24
rs2304589220101487TTC32ENSG00000183891.51.77E-70260gtex_brain_ba24
rs2304588220101717TTC32ENSG00000183891.56.973E-17030gtex_brain_ba24
rs2278528220101832TTC32ENSG00000183891.51.77E-70-85gtex_brain_ba24
rs7594214220106369TTC32ENSG00000183891.56.973E-170-4622gtex_brain_ba24
rs28742930220106598TTC32ENSG00000183891.51.77E-70-4851gtex_brain_ba24
rs62109404220106942TTC32ENSG00000183891.56.973E-170-5195gtex_brain_ba24
rs10175486220109061TTC32ENSG00000183891.51.77E-70-7314gtex_brain_ba24
rs62109406220115111TTC32ENSG00000183891.53.992E-160-13364gtex_brain_ba24
rs28502265220130145TTC32ENSG00000183891.57.476E-160-28398gtex_brain_ba24
rs12052274220131672TTC32ENSG00000183891.51.034E-120-29925gtex_brain_ba24
rs6755153220136292TTC32ENSG00000183891.58.735E-160-34545gtex_brain_ba24
rs2293671220137864TTC32ENSG00000183891.58.735E-160-36117gtex_brain_ba24
rs71990395220142309TTC32ENSG00000183891.53.884E-120-40562gtex_brain_ba24
rs10208878220142744TTC32ENSG00000183891.58.735E-160-40997gtex_brain_ba24
rs11096632220144372TTC32ENSG00000183891.58.735E-160-42625gtex_brain_ba24
rs6707471220146844TTC32ENSG00000183891.58.735E-160-45097gtex_brain_ba24
rs62109413220152116TTC32ENSG00000183891.58.735E-160-50369gtex_brain_ba24
rs62109415220154473TTC32ENSG00000183891.58.735E-160-52726gtex_brain_ba24
rs62109416220154959TTC32ENSG00000183891.58.796E-160-53212gtex_brain_ba24
rs6719397220155545TTC32ENSG00000183891.58.735E-160-53798gtex_brain_ba24
rs7589478220157495TTC32ENSG00000183891.58.735E-160-55748gtex_brain_ba24
rs12620863220158464TTC32ENSG00000183891.55.967E-130-56717gtex_brain_ba24
rs10169398220160209TTC32ENSG00000183891.58.735E-160-58462gtex_brain_ba24
rs12613209220162971TTC32ENSG00000183891.58.735E-160-61224gtex_brain_ba24
rs62109418220164291TTC32ENSG00000183891.58.735E-160-62544gtex_brain_ba24
rs10175095220164683TTC32ENSG00000183891.58.735E-160-62936gtex_brain_ba24
rs62109419220167001TTC32ENSG00000183891.58.735E-160-65254gtex_brain_ba24
rs28477921220171987TTC32ENSG00000183891.58.735E-160-70240gtex_brain_ba24
rs13415707220173673TTC32ENSG00000183891.58.735E-160-71926gtex_brain_ba24
rs16987265220174902TTC32ENSG00000183891.58.735E-160-73155gtex_brain_ba24
rs10197385220176574TTC32ENSG00000183891.58.735E-160-74827gtex_brain_ba24
rs1381817220179220TTC32ENSG00000183891.58.735E-160-77473gtex_brain_ba24
rs62109420220185765TTC32ENSG00000183891.58.735E-160-84018gtex_brain_ba24
rs62109421220186200TTC32ENSG00000183891.58.735E-160-84453gtex_brain_ba24
rs1060742220189015TTC32ENSG00000183891.58.735E-160-87268gtex_brain_ba24
rs10495701220197851TTC32ENSG00000183891.58.735E-160-96104gtex_brain_ba24
rs55977150220201922TTC32ENSG00000183891.58.735E-160-100175gtex_brain_ba24
rs10856792220208412TTC32ENSG00000183891.54.684E-70-106665gtex_brain_ba24
rs2006707220209618TTC32ENSG00000183891.52.537E-90-107871gtex_brain_ba24
rs113917580220212700TTC32ENSG00000183891.51.474E-80-110953gtex_brain_ba24
rs62109425220212942TTC32ENSG00000183891.51.529E-80-111195gtex_brain_ba24
rs62109426220213439TTC32ENSG00000183891.56.51E-150-111692gtex_brain_ba24
rs1147110220214880TTC32ENSG00000183891.53.754E-80-113133gtex_brain_ba24
rs62109397220082172TTC32ENSG00000183891.51.724E-7019575gtex_brain_putamen_basal
rs62109398220082748TTC32ENSG00000183891.51.674E-7018999gtex_brain_putamen_basal
rs13421472220082812TTC32ENSG00000183891.51.674E-7018935gtex_brain_putamen_basal
rs62109399220083373TTC32ENSG00000183891.51.674E-7018374gtex_brain_putamen_basal
rs12617761220088018TTC32ENSG00000183891.51.666E-7013729gtex_brain_putamen_basal
rs80296077220089000TTC32ENSG00000183891.51.655E-7012747gtex_brain_putamen_basal
rs35957485220090677TTC32ENSG00000183891.53.036E-9011070gtex_brain_putamen_basal
rs11888045220091890TTC32ENSG00000183891.53.009E-909857gtex_brain_putamen_basal
rs11889206220092032TTC32ENSG00000183891.53.002E-909715gtex_brain_putamen_basal
rs7563410220096936TTC32ENSG00000183891.52.894E-904811gtex_brain_putamen_basal
rs7572167220100988TTC32ENSG00000183891.51.961E-90759gtex_brain_putamen_basal
rs2304588220101717TTC32ENSG00000183891.52.894E-9030gtex_brain_putamen_basal
rs7594214220106369TTC32ENSG00000183891.52.894E-90-4622gtex_brain_putamen_basal
rs62109404220106942TTC32ENSG00000183891.52.894E-90-5195gtex_brain_putamen_basal
rs62109406220115111TTC32ENSG00000183891.57.133E-90-13364gtex_brain_putamen_basal
rs28502265220130145TTC32ENSG00000183891.58.775E-90-28398gtex_brain_putamen_basal
rs12052274220131672TTC32ENSG00000183891.57.097E-90-29925gtex_brain_putamen_basal
rs6755153220136292TTC32ENSG00000183891.59.233E-90-34545gtex_brain_putamen_basal
rs2293671220137864TTC32ENSG00000183891.59.233E-90-36117gtex_brain_putamen_basal
rs71990395220142309TTC32ENSG00000183891.51.523E-80-40562gtex_brain_putamen_basal
rs10208878220142744TTC32ENSG00000183891.59.233E-90-40997gtex_brain_putamen_basal
rs11096632220144372TTC32ENSG00000183891.59.233E-90-42625gtex_brain_putamen_basal
rs6707471220146844TTC32ENSG00000183891.59.764E-90-45097gtex_brain_putamen_basal
rs62109413220152116TTC32ENSG00000183891.59.233E-90-50369gtex_brain_putamen_basal
rs62109415220154473TTC32ENSG00000183891.59.233E-90-52726gtex_brain_putamen_basal
rs62109416220154959TTC32ENSG00000183891.59.272E-90-53212gtex_brain_putamen_basal
rs6719397220155545TTC32ENSG00000183891.59.233E-90-53798gtex_brain_putamen_basal
rs7589478220157495TTC32ENSG00000183891.59.233E-90-55748gtex_brain_putamen_basal
rs12620863220158464TTC32ENSG00000183891.53.823E-80-56717gtex_brain_putamen_basal
rs10169398220160209TTC32ENSG00000183891.59.233E-90-58462gtex_brain_putamen_basal
rs12613209220162971TTC32ENSG00000183891.59.233E-90-61224gtex_brain_putamen_basal
rs62109418220164291TTC32ENSG00000183891.59.227E-90-62544gtex_brain_putamen_basal
rs10175095220164683TTC32ENSG00000183891.59.227E-90-62936gtex_brain_putamen_basal
rs62109419220167001TTC32ENSG00000183891.59.215E-90-65254gtex_brain_putamen_basal
rs28477921220171987TTC32ENSG00000183891.59.227E-90-70240gtex_brain_putamen_basal
rs13415707220173673TTC32ENSG00000183891.59.227E-90-71926gtex_brain_putamen_basal
rs16987265220174902TTC32ENSG00000183891.59.227E-90-73155gtex_brain_putamen_basal
rs10197385220176574TTC32ENSG00000183891.59.233E-90-74827gtex_brain_putamen_basal
rs1381817220179220TTC32ENSG00000183891.59.233E-90-77473gtex_brain_putamen_basal
rs62109420220185765TTC32ENSG00000183891.59.233E-90-84018gtex_brain_putamen_basal
rs62109421220186200TTC32ENSG00000183891.59.233E-90-84453gtex_brain_putamen_basal
rs1060742220189015TTC32ENSG00000183891.59.233E-90-87268gtex_brain_putamen_basal
rs10495701220197851TTC32ENSG00000183891.51.063E-80-96104gtex_brain_putamen_basal
rs55977150220201922TTC32ENSG00000183891.59.233E-90-100175gtex_brain_putamen_basal
rs62109426220213439TTC32ENSG00000183891.52.232E-70-111692gtex_brain_putamen_basal

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
MARSON BOUND BY E2F4 UNSTIMULATED 728415All SZGR 2.0 genes in this pathway
ACEVEDO LIVER CANCER UP 973570All SZGR 2.0 genes in this pathway
ACEVEDO LIVER TUMOR VS NORMAL ADJACENT TISSUE UP 863514All SZGR 2.0 genes in this pathway
JOHNSTONE PARVB TARGETS 3 DN 918550All SZGR 2.0 genes in this pathway
ZWANG TRANSIENTLY UP BY 1ST EGF PULSE ONLY 1839928All SZGR 2.0 genes in this pathway