Summary ?
GeneID130540
SymbolALS2CR12
Synonyms-
Descriptionamyotrophic lateral sclerosis 2 chromosome region candidate 12
ReferenceHGNC:HGNC:14439|Ensembl:ENSG00000155749|HPRD:12444|Vega:OTTHUMG00000132824
Gene typeprotein-coding
Map location2q33.1
Pascal p-value0.074
Fetal beta-0.699
eGeneAnterior cingulate cortex BA24
Caudate basal ganglia
Cerebellum
Cortex
Frontal Cortex BA9
Hypothalamus
Nucleus accumbens basal ganglia
Putamen basal ganglia
Meta

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:GWASdbGenome-wide Association StudiesGWASdb records for schizophrenia
CV:PGCnpGenome-wide Association StudyGWAS

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs559711052202123717ALS2CR12ENSG00000155749.82.471E-7098404gtex_brain_ba24
rs67356562202124502ALS2CR12ENSG00000155749.83.576E-6097619gtex_brain_ba24
rs109319362202143928ALS2CR12ENSG00000155749.81.309E-6078193gtex_brain_ba24
rs108041112202145612ALS2CR12ENSG00000155749.81.966E-8076509gtex_brain_ba24
rs37698182202151163ALS2CR12ENSG00000155749.81.309E-6070958gtex_brain_ba24
rs31853782202151439ALS2CR12ENSG00000155749.81.966E-8070682gtex_brain_ba24
rs10351422202153078ALS2CR12ENSG00000155749.81.966E-8069043gtex_brain_ba24
rs7006352202153225ALS2CR12ENSG00000155749.81.309E-6068896gtex_brain_ba24
rs67144302202153684ALS2CR12ENSG00000155749.81.309E-6068437gtex_brain_ba24
rs67430682202153920ALS2CR12ENSG00000155749.81.309E-6068201gtex_brain_ba24
rs75874172202156054ALS2CR12ENSG00000155749.81.53E-7066067gtex_brain_ba24
rs130295112202161033ALS2CR12ENSG00000155749.81.169E-8061088gtex_brain_ba24
rs130169632202162811ALS2CR12ENSG00000155749.83.32E-8059310gtex_brain_ba24
rs92883162202163483ALS2CR12ENSG00000155749.81.964E-8058638gtex_brain_ba24
rs75603282202164837ALS2CR12ENSG00000155749.82.476E-8057284gtex_brain_ba24
rs1139626442202167651ALS2CR12ENSG00000155749.81.956E-8054470gtex_brain_ba24
rs67120912202169132ALS2CR12ENSG00000155749.84.383E-8052989gtex_brain_ba24
rs102002792202170655ALS2CR12ENSG00000155749.81.311E-6051466gtex_brain_ba24
rs67190142202176024ALS2CR12ENSG00000155749.81.314E-6046097gtex_brain_ba24
rs75823622202176294ALS2CR12ENSG00000155749.81.314E-6045827gtex_brain_ba24
rs67311712202179011ALS2CR12ENSG00000155749.86.759E-7043110gtex_brain_ba24
rs67356412202180491ALS2CR12ENSG00000155749.81.846E-8041630gtex_brain_ba24
rs18302982202181247ALS2CR12ENSG00000155749.81.928E-6040874gtex_brain_ba24
rs108041122202184165ALS2CR12ENSG00000155749.81.741E-8037956gtex_brain_ba24
rs96771802202184331ALS2CR12ENSG00000155749.81.346E-6037790gtex_brain_ba24
rs20803042202186422ALS2CR12ENSG00000155749.82.732E-8035699gtex_brain_ba24
rs23490732202186986ALS2CR12ENSG00000155749.81.305E-6035135gtex_brain_ba24
rs101972462202204741ALS2CR12ENSG00000155749.83.629E-6017380gtex_brain_ba24
rs109319332202112471ALS2CR12ENSG00000155749.84.244E-70109650gtex_brain_putamen_basal
rs129909062202114624ALS2CR12ENSG00000155749.82.52E-60107497gtex_brain_putamen_basal
rs116929522202116205ALS2CR12ENSG00000155749.82.52E-60105916gtex_brain_putamen_basal
rs75855082202118753ALS2CR12ENSG00000155749.82.52E-60103368gtex_brain_putamen_basal
rs109319342202119789ALS2CR12ENSG00000155749.82.52E-60102332gtex_brain_putamen_basal
rs37698232202122995ALS2CR12ENSG00000155749.81.465E-6099126gtex_brain_putamen_basal
rs37698212202123430ALS2CR12ENSG00000155749.84.296E-9098691gtex_brain_putamen_basal
rs593089632202123479ALS2CR12ENSG00000155749.88.515E-8098642gtex_brain_putamen_basal
rs559711052202123717ALS2CR12ENSG00000155749.83.995E-11098404gtex_brain_putamen_basal
rs67356562202124502ALS2CR12ENSG00000155749.87.029E-8097619gtex_brain_putamen_basal
rs67540842202124997ALS2CR12ENSG00000155749.82.336E-8097124gtex_brain_putamen_basal
rs18612702202126615ALS2CR12ENSG00000155749.82.192E-8095506gtex_brain_putamen_basal
rs67510532202127863ALS2CR12ENSG00000155749.85.021E-7094258gtex_brain_putamen_basal
rs64350742202127947ALS2CR12ENSG00000155749.82.11E-8094174gtex_brain_putamen_basal
rs67230972202128618ALS2CR12ENSG00000155749.84.951E-7093503gtex_brain_putamen_basal
rs37698202202130133ALS2CR12ENSG00000155749.84.797E-7091988gtex_brain_putamen_basal
rs23490702202130308ALS2CR12ENSG00000155749.81.992E-8091813gtex_brain_putamen_basal
rs130300422202138385ALS2CR12ENSG00000155749.81.174E-8083736gtex_brain_putamen_basal
rs81797862202143032ALS2CR12ENSG00000155749.82.393E-10079089gtex_brain_putamen_basal
rs109319362202143928ALS2CR12ENSG00000155749.86.024E-8078193gtex_brain_putamen_basal
rs108041112202145612ALS2CR12ENSG00000155749.85.437E-14076509gtex_brain_putamen_basal
rs37698182202151163ALS2CR12ENSG00000155749.85.974E-8070958gtex_brain_putamen_basal
rs31853782202151439ALS2CR12ENSG00000155749.84.75E-14070682gtex_brain_putamen_basal
rs10351422202153078ALS2CR12ENSG00000155749.84.75E-14069043gtex_brain_putamen_basal
rs7006352202153225ALS2CR12ENSG00000155749.85.974E-8068896gtex_brain_putamen_basal
rs7006362202153252ALS2CR12ENSG00000155749.82.215E-10068869gtex_brain_putamen_basal
rs67144302202153684ALS2CR12ENSG00000155749.85.974E-8068437gtex_brain_putamen_basal
rs67430682202153920ALS2CR12ENSG00000155749.85.974E-8068201gtex_brain_putamen_basal
rs75874172202156054ALS2CR12ENSG00000155749.81.967E-12066067gtex_brain_putamen_basal
rs101806582202158550ALS2CR12ENSG00000155749.87.183E-8063571gtex_brain_putamen_basal
rs130295112202161033ALS2CR12ENSG00000155749.84.382E-11061088gtex_brain_putamen_basal
rs130169632202162811ALS2CR12ENSG00000155749.81.941E-11059310gtex_brain_putamen_basal
rs92883162202163483ALS2CR12ENSG00000155749.84.758E-14058638gtex_brain_putamen_basal
rs75603282202164837ALS2CR12ENSG00000155749.87.605E-14057284gtex_brain_putamen_basal
rs20803032202165206ALS2CR12ENSG00000155749.81.287E-8056915gtex_brain_putamen_basal
rs1139626442202167651ALS2CR12ENSG00000155749.84.793E-14054470gtex_brain_putamen_basal
rs67120912202169132ALS2CR12ENSG00000155749.84.962E-10052989gtex_brain_putamen_basal
rs102002792202170655ALS2CR12ENSG00000155749.85.417E-8051466gtex_brain_putamen_basal
rs67190142202176024ALS2CR12ENSG00000155749.85.066E-8046097gtex_brain_putamen_basal
rs75823622202176294ALS2CR12ENSG00000155749.85.04E-8045827gtex_brain_putamen_basal
rs67311712202179011ALS2CR12ENSG00000155749.82.786E-11043110gtex_brain_putamen_basal
rs67356412202180491ALS2CR12ENSG00000155749.85.294E-14041630gtex_brain_putamen_basal
rs18302982202181247ALS2CR12ENSG00000155749.82.165E-8040874gtex_brain_putamen_basal
rs108041122202184165ALS2CR12ENSG00000155749.85.476E-14037956gtex_brain_putamen_basal
rs96771802202184331ALS2CR12ENSG00000155749.84.341E-8037790gtex_brain_putamen_basal
rs21106902202185132ALS2CR12ENSG00000155749.83.623E-7036989gtex_brain_putamen_basal
rs20803042202186422ALS2CR12ENSG00000155749.81.098E-11035699gtex_brain_putamen_basal
rs23490732202186986ALS2CR12ENSG00000155749.83.419E-8035135gtex_brain_putamen_basal
rs101972462202204741ALS2CR12ENSG00000155749.83.606E-8017380gtex_brain_putamen_basal
rs130361092202235943ALS2CR12ENSG00000155749.84.385E-60-13822gtex_brain_putamen_basal

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
BRUINS UVC RESPONSE VIA TP53 GROUP D 280158All SZGR 2.0 genes in this pathway