Gene Page: IL31RA
Summary ?
| GeneID | 133396 |
| Symbol | IL31RA |
| Synonyms | CRL|CRL3|GLM-R|GLMR|GPL|IL-31RA|PLCA2|PRO21384|hGLM-R |
| Description | interleukin 31 receptor A |
| Reference | MIM:609510|HGNC:HGNC:18969|Ensembl:ENSG00000164509|HPRD:17145|Vega:OTTHUMG00000097045 |
| Gene type | protein-coding |
| Map location | 5q11.2 |
| Pascal p-value | 0.605 |
| eGene | Myers' cis & trans |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS | |
| PMID:cooccur | High-throughput literature-search | Systematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included. | |
| Literature | High-throughput literature-search | Co-occurance with Schizophrenia keywords: schizophrenia,schizophrenias | Click to show details |
Section I. Genetics and epigenetics annotation
eQTL annotation
| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs10994209 | chr10 | 61877705 | IL31RA | 133396 | 0.17 | trans |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| RXRG | 0.87 | -0.13 |
| FAM40B | 0.86 | -0.16 |
| REM2 | 0.86 | 0.76 |
| FOXO1 | 0.85 | 0.34 |
| FAM155B | 0.84 | 0.82 |
| TSPAN9 | 0.84 | 0.54 |
| DACH1 | 0.84 | 0.50 |
| C13orf29 | 0.83 | 0.34 |
| SIX3 | 0.83 | 0.37 |
| AC021087.1 | 0.83 | 0.53 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| C5orf53 | -0.37 | -0.72 |
| CHPT1 | -0.35 | -0.55 |
| CA4 | -0.35 | -0.68 |
| PTH1R | -0.35 | -0.59 |
| AF347015.31 | -0.35 | -0.76 |
| MYL3 | -0.34 | -0.76 |
| ALDOC | -0.34 | -0.61 |
| COPZ2 | -0.34 | -0.69 |
| S100B | -0.34 | -0.70 |
| PLA2G4A | -0.34 | -0.61 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| HOOI ST7 TARGETS UP | 94 | 57 | All SZGR 2.0 genes in this pathway |
| TAKEDA TARGETS OF NUP98 HOXA9 FUSION 10D UP | 194 | 122 | All SZGR 2.0 genes in this pathway |
| TAKEDA TARGETS OF NUP98 HOXA9 FUSION 16D UP | 175 | 108 | All SZGR 2.0 genes in this pathway |
| TORCHIA TARGETS OF EWSR1 FLI1 FUSION DN | 321 | 200 | All SZGR 2.0 genes in this pathway |
| WAKABAYASHI ADIPOGENESIS PPARG RXRA BOUND 8D | 882 | 506 | All SZGR 2.0 genes in this pathway |