Summary ?
GeneID134701
SymbolRIPPLY2
SynonymsC6orf159|SCDO6|dJ237I15.1
Descriptionripply transcriptional repressor 2
ReferenceMIM:609891|HGNC:HGNC:21390|Ensembl:ENSG00000203877|HPRD:16658|Vega:OTTHUMG00000015117
Gene typeprotein-coding
Map location6q14.2
Pascal p-value0.46
Fetal beta-0.38
DMG1 (# studies)
eGeneMyers' cis & trans

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS
DMG:Jaffe_2016Genome-wide DNA methylation analysisThis dataset includes 2,104 probes/CpGs associated with SZ patients (n=108) compared to 136 controls at Bonferroni-adjusted P < 0.05. 1

Section I. Genetics and epigenetics annotation

@Differentially methylated gene

ProbeChromosomePositionNearest geneP (dis)Beta (dis)FDR (dis)Study
cg00772922684563042RIPPLY29.84E-9-0.0124.33E-6DMG:Jaffe_2016

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs3111196chr554402889RIPPLY21347010.05trans
rs16952206chr187606302RIPPLY21347010.16trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
BENPORATH ES WITH H3K27ME3 1118744All SZGR 2.0 genes in this pathway