Gene Page: COX11

Summary ?
GeneID1353
SymbolCOX11
SynonymsCOX11P
DescriptionCOX11 cytochrome c oxidase copper chaperone
ReferenceMIM:603648|HGNC:HGNC:2261|Ensembl:ENSG00000166260|HPRD:04709|Vega:OTTHUMG00000177838
Gene typeprotein-coding
Map location17q22
Pascal p-value0.018
Sherlock p-value0.934
eGeneCortex
Myers' cis & trans
Meta

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs12949718chr1752981852COX1113531.025E-6cis
rs9899602chr1752986907COX1113537.22E-6cis
rs17745123chr1752988231COX1113532.977E-7cis
rs9910653chr1752992267COX1113532.351E-7cis
rs17817829chr1753010380COX1113530cis
rs12936860chr1753030225COX1113532.934E-6cis
rs17817950chr1753045324COX1113531.203E-4cis
rs7222197chr1753047498COX1113535.202E-4cis
rs2628305chr1753140426COX1113530cis
rs1484769chr1753166650COX1113530.01cis
rs244348chr1753196290COX1113530.02cis
rs244317chr1753216984COX1113530.01cis
rs2628316chr1753219836COX1113530.01cis
rs17711168chr1753225016COX1113530.07cis
rs11677557chr2121317746COX1113530.16trans
rs12949718chr1752981852COX1113531.925E-4trans
rs9899602chr1752986907COX1113530trans
rs17745123chr1752988231COX1113536.089E-5trans
snp_a-21966220COX1113530.14trans
rs9910653chr1752992267COX1113534.923E-5trans
rs17817829chr1753010380COX1113530.11trans
rs12936860chr1753030225COX1113535.068E-4trans
rs17817950chr1753045324COX1113530.01trans
rs7222197chr1753047498COX1113530.04trans
rs80649310COX1113530.16trans
rs2628305chr1753140426COX1113530.13trans
rs10415150chr1952604624COX1113530.16trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
GenePearson's Correlation Spearman's Correlation
DMXL10.930.91
UBR30.920.90
WDR70.920.91
TMEM30A0.910.91
ATG2B0.900.89
DMXL20.900.89
COL4A3BP0.900.89
HIPK30.900.91
CXorf390.900.90
AKAP110.900.88
Top 10 negatively co-expressed genes
GenePearson's Correlation Spearman's Correlation
C1orf61-0.50-0.63
AL022328.1-0.47-0.53
C1orf54-0.46-0.51
RAB34-0.46-0.53
ENHO-0.46-0.51
AF347015.21-0.45-0.45
C19orf36-0.44-0.51
SAT1-0.44-0.48
EIF4EBP3-0.44-0.50
FXYD1-0.43-0.45

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
KEGG OXIDATIVE PHOSPHORYLATION 13573All SZGR 2.0 genes in this pathway
GAZDA DIAMOND BLACKFAN ANEMIA MYELOID DN 3825All SZGR 2.0 genes in this pathway
RHEIN ALL GLUCOCORTICOID THERAPY DN 362238All SZGR 2.0 genes in this pathway
HAHTOLA MYCOSIS FUNGOIDES CD4 DN 11671All SZGR 2.0 genes in this pathway
GAUSSMANN MLL AF4 FUSION TARGETS C UP 170114All SZGR 2.0 genes in this pathway
SCHLOSSER MYC TARGETS REPRESSED BY SERUM 15993All SZGR 2.0 genes in this pathway
PUJANA BRCA1 PCC NETWORK 16521023All SZGR 2.0 genes in this pathway
PUJANA BRCA2 PCC NETWORK 423265All SZGR 2.0 genes in this pathway
PUJANA CHEK2 PCC NETWORK 779480All SZGR 2.0 genes in this pathway
RICKMAN METASTASIS UP 344180All SZGR 2.0 genes in this pathway
NIKOLSKY BREAST CANCER 17Q21 Q25 AMPLICON 335181All SZGR 2.0 genes in this pathway
MOOTHA VOXPHOS 8751All SZGR 2.0 genes in this pathway
FLECHNER BIOPSY KIDNEY TRANSPLANT REJECTED VS OK DN 546351All SZGR 2.0 genes in this pathway
PENG RAPAMYCIN RESPONSE DN 245154All SZGR 2.0 genes in this pathway
IVANOVA HEMATOPOIESIS LATE PROGENITOR 544307All SZGR 2.0 genes in this pathway
BLALOCK ALZHEIMERS DISEASE DN 1237837All SZGR 2.0 genes in this pathway
KRIGE RESPONSE TO TOSEDOSTAT 6HR DN 911527All SZGR 2.0 genes in this pathway
KRIGE RESPONSE TO TOSEDOSTAT 24HR DN 1011592All SZGR 2.0 genes in this pathway
MARSON BOUND BY FOXP3 UNSTIMULATED 1229713All SZGR 2.0 genes in this pathway
WONG MITOCHONDRIA GENE MODULE 217122All SZGR 2.0 genes in this pathway
MOOTHA HUMAN MITODB 6 2002 429260All SZGR 2.0 genes in this pathway
MOOTHA MITOCHONDRIA 447277All SZGR 2.0 genes in this pathway
AGUIRRE PANCREATIC CANCER COPY NUMBER UP 298174All SZGR 2.0 genes in this pathway
JISON SICKLE CELL DISEASE DN 18197All SZGR 2.0 genes in this pathway