Summary ?
GeneID158038
SymbolLINGO2
SynonymsLERN3|LRRN6C
Descriptionleucine rich repeat and Ig domain containing 2
ReferenceMIM:609793|HGNC:HGNC:21207|Ensembl:ENSG00000174482|HPRD:08715|Vega:OTTHUMG00000019721
Gene typeprotein-coding
Map location9p21.2
Fetal beta-1.074
eGeneCerebellar Hemisphere
Cerebellum
Myers' cis & trans

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:GWASdbGenome-wide Association StudiesGWASdb records for schizophrenia
CV:PGCnpGenome-wide Association StudyGWAS

Section I. Genetics and epigenetics annotation

@DNM table

GeneChromosomePositionRefAltTranscriptAA changeMutation typeSiftCG46TraitStudy
LINGO2chr927949137CTNM_001258282
NM_152570
.
.
silent
silent
SchizophreniaDNM:Fromer_2014

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs10968120chr927804539LINGO21580380.09cis
rs6446945chr471791501LINGO21580380.03trans
rs7760808chr648481947LINGO21580380.12trans
rs9343156chr675130735LINGO21580380.19trans
rs6118558chr209263913LINGO21580380.18trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
ACEVEDO METHYLATED IN LIVER CANCER DN 940425All SZGR 2.0 genes in this pathway
BOYLAN MULTIPLE MYELOMA C DN 5939All SZGR 2.0 genes in this pathway
PHESSE TARGETS OF APC AND MBD2 UP 2014All SZGR 2.0 genes in this pathway