Summary ?
GeneID1791
SymbolDNTT
SynonymsTDT
DescriptionDNA nucleotidylexotransferase
ReferenceMIM:187410|HGNC:HGNC:2983|Ensembl:ENSG00000107447|HPRD:08925|Vega:OTTHUMG00000018832
Gene typeprotein-coding
Map location10q23-q24
Pascal p-value0.019

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS

Section I. Genetics and epigenetics annotation


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
GenePearson's Correlation Spearman's Correlation
KHDRBS30.850.89
NELL20.820.84
KLHL10.820.81
NEUROD60.810.86
C6orf1150.790.80
AKT30.790.78
SRPK10.790.79
ZNF2380.790.85
COMMD20.780.77
TMEM570.780.78
Top 10 negatively co-expressed genes
GenePearson's Correlation Spearman's Correlation
HSD17B14-0.65-0.75
TTYH1-0.63-0.68
TSC22D4-0.63-0.73
AIFM3-0.62-0.71
FAH-0.62-0.70
SERPINB6-0.62-0.67
HEPN1-0.62-0.69
BDH2-0.61-0.71
RAMP1-0.61-0.71
UBTD1-0.60-0.67

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
KEGG NON HOMOLOGOUS END JOINING 148All SZGR 2.0 genes in this pathway
KEGG HEMATOPOIETIC CELL LINEAGE 8860All SZGR 2.0 genes in this pathway
PID DNA PK PATHWAY 1610All SZGR 2.0 genes in this pathway
PID MYC REPRESS PATHWAY 6352All SZGR 2.0 genes in this pathway
DIAZ CHRONIC MEYLOGENOUS LEUKEMIA DN 11679All SZGR 2.0 genes in this pathway
GRABARCZYK BCL11B TARGETS DN 5735All SZGR 2.0 genes in this pathway
RHEIN ALL GLUCOCORTICOID THERAPY DN 362238All SZGR 2.0 genes in this pathway
PUJANA BRCA2 PCC NETWORK 423265All SZGR 2.0 genes in this pathway
WEI MYCN TARGETS WITH E BOX 795478All SZGR 2.0 genes in this pathway
MORI PRE BI LYMPHOCYTE UP 8054All SZGR 2.0 genes in this pathway
MORI MATURE B LYMPHOCYTE DN 7543All SZGR 2.0 genes in this pathway
KAUFFMANN DNA REPLICATION GENES 14787All SZGR 2.0 genes in this pathway
BYSTRYKH HEMATOPOIESIS STEM CELL QTL TRANS 882572All SZGR 2.0 genes in this pathway
FERRANDO T ALL WITH MLL ENL FUSION DN 8757All SZGR 2.0 genes in this pathway
HADDAD B LYMPHOCYTE PROGENITOR 293193All SZGR 2.0 genes in this pathway
HADDAD T LYMPHOCYTE AND NK PROGENITOR DN 6341All SZGR 2.0 genes in this pathway
VERHAAK AML WITH NPM1 MUTATED DN 246180All SZGR 2.0 genes in this pathway
KAMMINGA EZH2 TARGETS 4126All SZGR 2.0 genes in this pathway
KUMAR TARGETS OF MLL AF9 FUSION 405264All SZGR 2.0 genes in this pathway
KAYO AGING MUSCLE DN 12376All SZGR 2.0 genes in this pathway
IVANOVA HEMATOPOIESIS STEM CELL SHORT TERM 3215All SZGR 2.0 genes in this pathway
MARSON BOUND BY FOXP3 UNSTIMULATED 1229713All SZGR 2.0 genes in this pathway
MARSON FOXP3 TARGETS STIMULATED DN 119All SZGR 2.0 genes in this pathway
QI PLASMACYTOMA UP 259185All SZGR 2.0 genes in this pathway
HOFFMANN PRE BI TO LARGE PRE BII LYMPHOCYTE DN 7561All SZGR 2.0 genes in this pathway
LEE EARLY T LYMPHOCYTE UP 10759All SZGR 2.0 genes in this pathway
FERRANDO HOX11 NEIGHBORS 2313All SZGR 2.0 genes in this pathway
CHIARETTI T ALL REFRACTORY TO THERAPY 3018All SZGR 2.0 genes in this pathway
DANG REGULATED BY MYC DN 253192All SZGR 2.0 genes in this pathway
DANG MYC TARGETS DN 3125All SZGR 2.0 genes in this pathway
DANG BOUND BY MYC 1103714All SZGR 2.0 genes in this pathway
WONG ADULT TISSUE STEM MODULE 721492All SZGR 2.0 genes in this pathway
LI INDUCED T TO NATURAL KILLER DN 11683All SZGR 2.0 genes in this pathway
CHYLA CBFA2T3 TARGETS UP 387225All SZGR 2.0 genes in this pathway
ZWANG TRANSIENTLY UP BY 2ND EGF PULSE ONLY 1725838All SZGR 2.0 genes in this pathway