Summary ?
GeneID221091
SymbolLRRN4CL
Synonyms-
DescriptionLRRN4 C-terminal like
ReferenceHGNC:HGNC:33724|Ensembl:ENSG00000177363|HPRD:17322|Vega:OTTHUMG00000167581
Gene typeprotein-coding
Map location11q12.3
Pascal p-value0.704
Fetal beta-0.313
DMG1 (# studies)
eGeneMyers' cis & trans

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
DMG:Wockner_2014Genome-wide DNA methylation analysisThis dataset includes 4641 differentially methylated probes corresponding to 2929 unique genes between schizophrenia patients (n=24) and controls (n=24). 1

Section I. Genetics and epigenetics annotation

@Differentially methylated gene

ProbeChromosomePositionNearest geneP (dis)Beta (dis)FDR (dis)Study
cg200513141162456939LRRN4CL2.725E-40.4990.038DMG:Wockner_2014

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs17131472chr191962966LRRN4CL2210910.1trans
rs1473237chr1191045246LRRN4CL2210910.17trans
rs17589268chr1219457257LRRN4CL2210910.17trans
rs2922180chr3125280472LRRN4CL2210910.17trans
rs2976809chr3125451738LRRN4CL2210910.04trans
rs10050805chr530805352LRRN4CL2210910.12trans
rs17056435chr5158453782LRRN4CL2210910.12trans
rs6455226chr667930295LRRN4CL2210910trans
rs9451867chr692659609LRRN4CL2210910.15trans
rs11783167chr8129102799LRRN4CL2210910.19trans
rs12229182chr1227263631LRRN4CL2210910.16trans
rs11112163chr12105072508LRRN4CL2210910.05trans
rs9551590chr1329589464LRRN4CL2210910.19trans
rs10142086chr1435135892LRRN4CL2210910.14trans
rs11873703chr1861448702LRRN4CL2210910.17trans
rs6095741chr2048666589LRRN4CL2210912.546E-4trans
rs5991662chrX43335796LRRN4CL2210910.01trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
GAUSSMANN MLL AF4 FUSION TARGETS A DN 9061All SZGR 2.0 genes in this pathway
SCHAEFFER PROSTATE DEVELOPMENT 6HR UP 176115All SZGR 2.0 genes in this pathway
ROZANOV MMP14 TARGETS UP 266171All SZGR 2.0 genes in this pathway
MIKKELSEN ES ICP WITH H3K4ME3 718401All SZGR 2.0 genes in this pathway
ZHOU CELL CYCLE GENES IN IR RESPONSE 24HR 12873All SZGR 2.0 genes in this pathway