Gene Page: FGF7

Summary ?
GeneID2252
SymbolFGF7
SynonymsHBGF-7|KGF
Descriptionfibroblast growth factor 7
ReferenceMIM:148180|HGNC:HGNC:3685|Ensembl:ENSG00000140285|HPRD:01022|
Gene typeprotein-coding
Map location15q21.2
Pascal p-value0.141
Fetal beta0.16
eGeneMyers' cis & trans

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS
PMID:cooccurHigh-throughput literature-searchSystematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included.
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: schizophrenia,schizophreniasClick to show details

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs933856chr1550483735FGF722520.14cis

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
GenePearson's Correlation Spearman's Correlation
ACSS30.430.39
MYO60.420.39
RHOQ0.420.37
CIITA0.410.32
MID1IP10.410.32
CALCOCO20.400.40
QKI0.400.37
DOCK10.400.39
PMP20.400.32
KAT2B0.390.30
Top 10 negatively co-expressed genes
GenePearson's Correlation Spearman's Correlation
RPRM-0.23-0.20
TG-0.22-0.19
LRFN2-0.20-0.15
AC011491.1-0.20-0.17
CD1D-0.20-0.15
TUBA1C-0.19-0.23
MPPED1-0.19-0.11
NPY1R-0.19-0.13
RASGEF1C-0.19-0.11
LRFN4-0.19-0.15

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
KEGG MAPK SIGNALING PATHWAY 267205All SZGR 2.0 genes in this pathway
KEGG REGULATION OF ACTIN CYTOSKELETON 216144All SZGR 2.0 genes in this pathway
KEGG PATHWAYS IN CANCER 328259All SZGR 2.0 genes in this pathway
KEGG MELANOMA 7157All SZGR 2.0 genes in this pathway
REACTOME NEGATIVE REGULATION OF FGFR SIGNALING 3724All SZGR 2.0 genes in this pathway
REACTOME INSULIN RECEPTOR SIGNALLING CASCADE 8764All SZGR 2.0 genes in this pathway
REACTOME SIGNALING BY FGFR IN DISEASE 12788All SZGR 2.0 genes in this pathway
REACTOME ACTIVATED POINT MUTANTS OF FGFR2 1611All SZGR 2.0 genes in this pathway
REACTOME SIGNALING BY FGFR MUTANTS 4429All SZGR 2.0 genes in this pathway
REACTOME FRS2 MEDIATED CASCADE 3627All SZGR 2.0 genes in this pathway
REACTOME PI 3K CASCADE 5639All SZGR 2.0 genes in this pathway
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR 10074All SZGR 2.0 genes in this pathway
REACTOME PHOSPHOLIPASE C MEDIATED CASCADE 5440All SZGR 2.0 genes in this pathway
REACTOME SHC MEDIATED CASCADE 2819All SZGR 2.0 genes in this pathway
REACTOME SIGNALING BY INSULIN RECEPTOR 10872All SZGR 2.0 genes in this pathway
REACTOME FGFR LIGAND BINDING AND ACTIVATION 2215All SZGR 2.0 genes in this pathway
REACTOME SIGNALING BY FGFR 11280All SZGR 2.0 genes in this pathway
REACTOME PI3K CASCADE 7151All SZGR 2.0 genes in this pathway
ZHOU INFLAMMATORY RESPONSE LIVE DN 384220All SZGR 2.0 genes in this pathway
ZHOU INFLAMMATORY RESPONSE FIMA DN 284156All SZGR 2.0 genes in this pathway
CHIARADONNA NEOPLASTIC TRANSFORMATION CDC25 UP 12073All SZGR 2.0 genes in this pathway
NUYTTEN EZH2 TARGETS UP 1037673All SZGR 2.0 genes in this pathway
CHEN NEUROBLASTOMA COPY NUMBER GAINS 5035All SZGR 2.0 genes in this pathway
LE EGR2 TARGETS DN 10884All SZGR 2.0 genes in this pathway
GERY CEBP TARGETS 12690All SZGR 2.0 genes in this pathway
AFFAR YY1 TARGETS DN 234137All SZGR 2.0 genes in this pathway
BROWNE HCMV INFECTION 14HR DN 298200All SZGR 2.0 genes in this pathway
SIMBULAN PARP1 TARGETS UP 3123All SZGR 2.0 genes in this pathway
GERHOLD ADIPOGENESIS DN 6444All SZGR 2.0 genes in this pathway
BURTON ADIPOGENESIS 8 8657All SZGR 2.0 genes in this pathway
ZHU CMV 8 HR DN 5340All SZGR 2.0 genes in this pathway
ZHU CMV ALL DN 12893All SZGR 2.0 genes in this pathway
BROWNE HCMV INFECTION 12HR DN 10164All SZGR 2.0 genes in this pathway
MARSON BOUND BY FOXP3 STIMULATED 1022619All SZGR 2.0 genes in this pathway
MARTINEZ RB1 TARGETS UP 673430All SZGR 2.0 genes in this pathway
MARTINEZ TP53 TARGETS DN 593372All SZGR 2.0 genes in this pathway
MARTINEZ RB1 AND TP53 TARGETS DN 591366All SZGR 2.0 genes in this pathway
MARZEC IL2 SIGNALING UP 11580All SZGR 2.0 genes in this pathway
BONCI TARGETS OF MIR15A AND MIR16 1 9175All SZGR 2.0 genes in this pathway
BOQUEST STEM CELL UP 260174All SZGR 2.0 genes in this pathway
LABBE WNT3A TARGETS DN 9753All SZGR 2.0 genes in this pathway
SWEET LUNG CANCER KRAS DN 435289All SZGR 2.0 genes in this pathway
COLINA TARGETS OF 4EBP1 AND 4EBP2 356214All SZGR 2.0 genes in this pathway
MCMURRAY TP53 HRAS COOPERATION RESPONSE UP 2619All SZGR 2.0 genes in this pathway
MIKKELSEN DEDIFFERENTIATED STATE DN 77All SZGR 2.0 genes in this pathway
MILI PSEUDOPODIA CHEMOTAXIS DN 457302All SZGR 2.0 genes in this pathway
BRUINS UVC RESPONSE VIA TP53 GROUP C 9260All SZGR 2.0 genes in this pathway
LEE BMP2 TARGETS DN 882538All SZGR 2.0 genes in this pathway
PLASARI TGFB1 TARGETS 10HR DN 244157All SZGR 2.0 genes in this pathway
PLASARI TGFB1 SIGNALING VIA NFIC 10HR UP 5438All SZGR 2.0 genes in this pathway
NABA SECRETED FACTORS 344197All SZGR 2.0 genes in this pathway
NABA MATRISOME ASSOCIATED 753411All SZGR 2.0 genes in this pathway
NABA MATRISOME 1028559All SZGR 2.0 genes in this pathway