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| GeneID |
22803
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| Symbol |
XRN2
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| Synonyms |
-
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| Description |
5'-3' exoribonuclease 2 |
| See related |
HGNC:12836|MIM:608851|Ensembl:ENSG00000088930|HPRD:10309| |
| Locus tag |
RP11-227D2.1 |
| Gene type |
protein-coding |
| Map location |
20p11.2-p11.1 |
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| Gene set name |
Method of gene set |
Evidence |
Info |
| Network | Shortest path distance of core genes in the Human protein-protein interaction network | Contribution to shortest path in PPI network: 1.9018 | |
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| General Gene Expression (microarray) ? |
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| Gene Expression in Brain Regions (new) |
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| Top co-expressed genes in Brain Regions (new) |
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| Gene | Pearson's Correlation | Spearman's Correlation | | |
| Top 10 positively co-expressed genes |
| KIF13A | 0.84 | 0.84 | | |
| CC2D1B | 0.81 | 0.84 | | |
| PHLDB1 | 0.81 | 0.83 | | |
| FRYL | 0.80 | 0.81 | | |
| KIAA0562 | 0.79 | 0.82 | | |
| ZFYVE16 | 0.79 | 0.79 | | |
| RNF213 | 0.79 | 0.81 | | |
| ATP11A | 0.79 | 0.80 | | |
| WWC3 | 0.79 | 0.82 | | |
| XPC | 0.79 | 0.81 | | |
Top 10 negatively co-expressed genes | | UQCR | -0.50 | -0.60 | | |
| AC044839.2 | -0.49 | -0.45 | | |
| C1orf61 | -0.49 | -0.45 | | |
| NDUFB2 | -0.49 | -0.50 | | |
| C1orf54 | -0.49 | -0.48 | | |
| TIMM8B | -0.49 | -0.51 | | |
| UQCRQ | -0.48 | -0.54 | | |
| ENHO | -0.48 | -0.48 | | |
| IL32 | -0.48 | -0.50 | | |
| SERF2 | -0.48 | -0.50 | | |
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| Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0003676 | nucleic acid binding | IEA | | - |
| GO:0005515 | protein binding | IPI | | 15231747 |
| GO:0004534 | 5'-3' exoribonuclease activity | TAS | | 10409438 |
| GO:0016787 | hydrolase activity | IEA | | - |
| GO:0008270 | zinc ion binding | IEA | | - |
| GO:0046872 | metal ion binding | IEA | | - |
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0000738 | DNA catabolic process, exonucleolytic | IDA | | 15565158 |
| GO:0006353 | transcription termination | IEA | | - |
| GO:0006355 | regulation of transcription, DNA-dependent | IEA | | - |
| GO:0006397 | mRNA processing | IEA | | - |
| GO:0006350 | transcription | IEA | | - |
| GO:0006401 | RNA catabolic process | TAS | | 10409438 |
| GO:0016049 | cell growth | ISS | | - |
| GO:0007283 | spermatogenesis | IEP | | 10409438 |
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0005622 | intracellular | IEA | | - |
| GO:0005634 | nucleus | TAS | | 10409438 |
| GO:0005730 | nucleolus | IDA | | 12429849 |
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- SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
- Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.
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