Gene Page: AVL9

Summary ?
GeneID23080
SymbolAVL9
SynonymsKIAA0241
DescriptionAVL9 cell migration associated
ReferenceMIM:612927|HGNC:HGNC:28994|Ensembl:ENSG00000105778|HPRD:13788|Vega:OTTHUMG00000152929
Gene typeprotein-coding
Map location7p14.3
Pascal p-value0.063
Fetal beta-0.448
DMG1 (# studies)
eGeneMeta

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS
DMG:Jaffe_2016Genome-wide DNA methylation analysisThis dataset includes 2,104 probes/CpGs associated with SZ patients (n=108) compared to 136 controls at Bonferroni-adjusted P < 0.05. 2

Section I. Genetics and epigenetics annotation

@Differentially methylated gene

ProbeChromosomePositionNearest geneP (dis)Beta (dis)FDR (dis)Study
cg24077501732996869AVL91.26E-9-0.0151.32E-6DMG:Jaffe_2016
cg20743544732982957AVL94.09E-9-0.0242.49E-6DMG:Jaffe_2016


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
GenePearson's Correlation Spearman's Correlation
C1orf580.880.90
KIAA01960.860.88
MON20.860.88
FRS20.860.89
IPO80.850.87
SETX0.850.88
FNIP10.850.87
FRYL0.840.87
LARP40.840.87
ITCH0.840.86
Top 10 negatively co-expressed genes
GenePearson's Correlation Spearman's Correlation
IL32-0.57-0.59
CXCL14-0.56-0.60
IFI27-0.55-0.60
AF347015.21-0.54-0.54
MT-CO2-0.53-0.56
ENHO-0.53-0.63
CSAG1-0.53-0.53
FXYD1-0.52-0.56
HIGD1B-0.52-0.57
C16orf14-0.51-0.62

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
CHARAFE BREAST CANCER LUMINAL VS BASAL UP 380215All SZGR 2.0 genes in this pathway
HAHTOLA MYCOSIS FUNGOIDES CD4 DN 11671All SZGR 2.0 genes in this pathway
GAUSSMANN MLL AF4 FUSION TARGETS G UP 238135All SZGR 2.0 genes in this pathway
MCBRYAN PUBERTAL BREAST 5 6WK UP 11668All SZGR 2.0 genes in this pathway
DACOSTA UV RESPONSE VIA ERCC3 XPCS DN 8871All SZGR 2.0 genes in this pathway
DACOSTA UV RESPONSE VIA ERCC3 TTD DN 8463All SZGR 2.0 genes in this pathway
DACOSTA UV RESPONSE VIA ERCC3 DN 855609All SZGR 2.0 genes in this pathway
BENPORATH NANOG TARGETS 988594All SZGR 2.0 genes in this pathway
BENPORATH PROLIFERATION 14780All SZGR 2.0 genes in this pathway
GALE APL WITH FLT3 MUTATED UP 5635All SZGR 2.0 genes in this pathway
MOREAUX MULTIPLE MYELOMA BY TACI DN 172107All SZGR 2.0 genes in this pathway
KONDO EZH2 TARGETS 245148All SZGR 2.0 genes in this pathway
MITSIADES RESPONSE TO APLIDIN DN 249165All SZGR 2.0 genes in this pathway
CHEN HOXA5 TARGETS 9HR UP 223132All SZGR 2.0 genes in this pathway
CAIRO HEPATOBLASTOMA UP 207143All SZGR 2.0 genes in this pathway
BROWNE HCMV INFECTION 4HR DN 254158All SZGR 2.0 genes in this pathway
CHANGOLKAR H2AFY TARGETS UP 4828All SZGR 2.0 genes in this pathway
ZWANG TRANSIENTLY UP BY 1ST EGF PULSE ONLY 1839928All SZGR 2.0 genes in this pathway