Gene Page: GPATCH8
Summary ?
| GeneID | 23131 |
| Symbol | GPATCH8 |
| Synonyms | GPATC8|KIAA0553 |
| Description | G-patch domain containing 8 |
| Reference | MIM:614396|HGNC:HGNC:29066|HPRD:11089| |
| Gene type | protein-coding |
| Map location | 17q21.31 |
| Pascal p-value | 0.021 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| RNF141 | 0.88 | 0.84 |
| DNAJC3 | 0.86 | 0.83 |
| ACAP2 | 0.86 | 0.83 |
| CCDC47 | 0.84 | 0.83 |
| USP8 | 0.84 | 0.85 |
| FAR1 | 0.84 | 0.82 |
| RAB21 | 0.84 | 0.81 |
| ADAM9 | 0.83 | 0.83 |
| STK38L | 0.83 | 0.86 |
| MPP5 | 0.83 | 0.84 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| IL32 | -0.48 | -0.37 |
| NUDT8 | -0.47 | -0.51 |
| C1orf61 | -0.45 | -0.42 |
| AF347015.21 | -0.43 | -0.20 |
| AL022328.1 | -0.43 | -0.41 |
| HES4 | -0.42 | -0.45 |
| CLEC3B | -0.41 | -0.45 |
| IRF7 | -0.41 | -0.48 |
| ENHO | -0.41 | -0.38 |
| AC016757.1 | -0.41 | -0.36 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| GRAESSMANN APOPTOSIS BY DOXORUBICIN DN | 1781 | 1082 | All SZGR 2.0 genes in this pathway |
| DACOSTA UV RESPONSE VIA ERCC3 XPCS DN | 88 | 71 | All SZGR 2.0 genes in this pathway |
| DACOSTA UV RESPONSE VIA ERCC3 TTD DN | 84 | 63 | All SZGR 2.0 genes in this pathway |
| DACOSTA UV RESPONSE VIA ERCC3 DN | 855 | 609 | All SZGR 2.0 genes in this pathway |
| BUYTAERT PHOTODYNAMIC THERAPY STRESS UP | 811 | 508 | All SZGR 2.0 genes in this pathway |
| STARK PREFRONTAL CORTEX 22Q11 DELETION DN | 517 | 309 | All SZGR 2.0 genes in this pathway |
| JIANG HYPOXIA NORMAL | 311 | 205 | All SZGR 2.0 genes in this pathway |
| AGUIRRE PANCREATIC CANCER COPY NUMBER UP | 298 | 174 | All SZGR 2.0 genes in this pathway |
| JISON SICKLE CELL DISEASE DN | 181 | 97 | All SZGR 2.0 genes in this pathway |
| KYNG WERNER SYNDROM AND NORMAL AGING DN | 225 | 124 | All SZGR 2.0 genes in this pathway |
| MARTENS BOUND BY PML RARA FUSION | 456 | 287 | All SZGR 2.0 genes in this pathway |
| PILON KLF1 TARGETS DN | 1972 | 1213 | All SZGR 2.0 genes in this pathway |
| ZWANG TRANSIENTLY UP BY 1ST EGF PULSE ONLY | 1839 | 928 | All SZGR 2.0 genes in this pathway |