Gene Page: FAM175B
Summary ?
| GeneID | 23172 |
| Symbol | FAM175B |
| Synonyms | ABRO1|KIAA0157 |
| Description | family with sequence similarity 175 member B |
| Reference | MIM:611144|HGNC:HGNC:28975|Ensembl:ENSG00000165660|HPRD:13783|Vega:OTTHUMG00000019218 |
| Gene type | protein-coding |
| Map location | 10q26.13 |
| Pascal p-value | 0.022 |
| Sherlock p-value | 0.579 |
| Fetal beta | -0.055 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:GWASdb | Genome-wide Association Studies | GWASdb records for schizophrenia | |
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression during devlopment (BrainCloud)
Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| TARS2 | 0.80 | 0.78 |
| ACAD9 | 0.80 | 0.77 |
| COG8 | 0.79 | 0.81 |
| REEP2 | 0.79 | 0.75 |
| MAEA | 0.78 | 0.79 |
| OTUD5 | 0.78 | 0.78 |
| AAMP | 0.78 | 0.76 |
| ALG2 | 0.77 | 0.76 |
| CLPTM1L | 0.77 | 0.77 |
| PWP2H | 0.77 | 0.75 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| AF347015.21 | -0.65 | -0.52 |
| AF347015.31 | -0.60 | -0.51 |
| AF347015.8 | -0.59 | -0.51 |
| MT-CO2 | -0.59 | -0.50 |
| AF347015.2 | -0.56 | -0.44 |
| MT-CYB | -0.56 | -0.47 |
| AF347015.27 | -0.55 | -0.49 |
| AF347015.33 | -0.55 | -0.45 |
| MT-ATP8 | -0.54 | -0.52 |
| AF347015.18 | -0.53 | -0.43 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| OSMAN BLADDER CANCER UP | 404 | 246 | All SZGR 2.0 genes in this pathway |
| OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL DN | 275 | 168 | All SZGR 2.0 genes in this pathway |
| LASTOWSKA NEUROBLASTOMA COPY NUMBER DN | 800 | 473 | All SZGR 2.0 genes in this pathway |
| PUJANA BRCA1 PCC NETWORK | 1652 | 1023 | All SZGR 2.0 genes in this pathway |
| KUROKAWA LIVER CANCER CHEMOTHERAPY DN | 41 | 28 | All SZGR 2.0 genes in this pathway |
| CHEOK RESPONSE TO HD MTX DN | 24 | 18 | All SZGR 2.0 genes in this pathway |
| DEBIASI APOPTOSIS BY REOVIRUS INFECTION UP | 314 | 201 | All SZGR 2.0 genes in this pathway |
| MARTINEZ RESPONSE TO TRABECTEDIN DN | 271 | 175 | All SZGR 2.0 genes in this pathway |
| KONDO EZH2 TARGETS | 245 | 148 | All SZGR 2.0 genes in this pathway |
| ZWANG CLASS 1 TRANSIENTLY INDUCED BY EGF | 516 | 308 | All SZGR 2.0 genes in this pathway |