Gene Page: FAM168A
Summary ?
| GeneID | 23201 |
| Symbol | FAM168A |
| Synonyms | KIAA0280|TCRP1 |
| Description | family with sequence similarity 168 member A |
| Reference | MIM:616316|HGNC:HGNC:28999|Ensembl:ENSG00000054965|Vega:OTTHUMG00000167995 |
| Gene type | protein-coding |
| Map location | 11q13.4 |
| Pascal p-value | 0.01 |
| Sherlock p-value | 0.818 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| TMEM144 | 0.95 | 0.74 |
| CLDND1 | 0.95 | 0.86 |
| UGT8 | 0.93 | 0.78 |
| FOLH1 | 0.92 | 0.77 |
| ENPP2 | 0.92 | 0.72 |
| PLP1 | 0.92 | 0.72 |
| ERMN | 0.92 | 0.74 |
| ABCA8 | 0.92 | 0.72 |
| GPR37 | 0.91 | 0.80 |
| NPC1 | 0.90 | 0.80 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| TBC1D10A | -0.50 | -0.50 |
| MMP25 | -0.47 | -0.55 |
| LRFN4 | -0.47 | -0.49 |
| AC009133.1 | -0.46 | -0.51 |
| PBX4 | -0.46 | -0.51 |
| C1orf86 | -0.46 | -0.55 |
| CCDC28B | -0.45 | -0.59 |
| C17orf70 | -0.45 | -0.45 |
| AC011491.1 | -0.45 | -0.53 |
| EMID1 | -0.45 | -0.51 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| LASTOWSKA NEUROBLASTOMA COPY NUMBER DN | 800 | 473 | All SZGR 2.0 genes in this pathway |
| DACOSTA UV RESPONSE VIA ERCC3 XPCS DN | 88 | 71 | All SZGR 2.0 genes in this pathway |
| DACOSTA UV RESPONSE VIA ERCC3 TTD DN | 84 | 63 | All SZGR 2.0 genes in this pathway |
| DACOSTA UV RESPONSE VIA ERCC3 DN | 855 | 609 | All SZGR 2.0 genes in this pathway |
| BENPORATH SOX2 TARGETS | 734 | 436 | All SZGR 2.0 genes in this pathway |
| SHEN SMARCA2 TARGETS UP | 424 | 268 | All SZGR 2.0 genes in this pathway |
| IVANOVA HEMATOPOIESIS STEM CELL LONG TERM | 302 | 191 | All SZGR 2.0 genes in this pathway |
| BROWNE HCMV INFECTION 18HR UP | 178 | 111 | All SZGR 2.0 genes in this pathway |
| BROWNE HCMV INFECTION 6HR DN | 160 | 101 | All SZGR 2.0 genes in this pathway |
| BILD MYC ONCOGENIC SIGNATURE | 206 | 117 | All SZGR 2.0 genes in this pathway |
| PILON KLF1 TARGETS DN | 1972 | 1213 | All SZGR 2.0 genes in this pathway |