Gene Page: PLCL2

Summary
GeneID  23228
Symbol  PLCL2
Synonyms  FLJ13484|KIAA1092|PLCE2
Description  phospholipase C-like 2
See related  HGNC:9064|Ensembl:ENSG00000154822|HPRD:07147|
Locus tag  -
Gene type  protein-coding
Map location  3p24.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.006 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
DIS30.950.95
OSBPL110.950.95
GSPT10.950.96
VEZT0.950.94
TAF20.950.94
WDR480.950.95
NUP1330.950.96
GART0.940.94
WDR30.940.94
ZMYM40.940.94
Top 10 negatively co-expressed genes
AF347015.31-0.79-0.87
MT-CO2-0.79-0.88
AF347015.27-0.77-0.85
AF347015.8-0.76-0.87
AF347015.33-0.76-0.84
MT-CYB-0.75-0.84
IFI27-0.74-0.84
FXYD1-0.74-0.84
HLA-F-0.73-0.75
AF347015.15-0.73-0.84
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004871signal transducer activityIEA-
GO:0005509calcium ion bindingIEA-
GO:0004435phosphoinositide phospholipase C activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007242intracellular signaling cascadeIEA-
GO:0006629lipid metabolic processIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005737cytoplasmIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
DSCAML1KIAA1132Down syndrome cell adhesion molecule like 1-HPRD12421765 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
BERTUCCI_MEDULLARY_VS_DUCTAL_BREAST_CANCER_UP 206111All SZGR genes in this pathway
FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_DN 463290All SZGR genes in this pathway
ZHOU_INFLAMMATORY_RESPONSE_LIVE_DN 384220All SZGR genes in this pathway
GOZGIT_ESR1_TARGETS_UP 14984All SZGR genes in this pathway
FARMER_BREAST_CANCER_APOCRINE_VS_BASAL 330217All SZGR genes in this pathway
SCHLOSSER_SERUM_RESPONSE_DN 712443All SZGR genes in this pathway
PUJANA_ATM_PCC_NETWORK 1442892All SZGR genes in this pathway
NUYTTEN_NIPP1_TARGETS_DN 848527All SZGR genes in this pathway
BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_DN 637377All SZGR genes in this pathway
FAELT_B_CLL_WITH_VH_REARRANGEMENTS_DN 4826All SZGR genes in this pathway
FAELT_B_CLL_WITH_VH3_21_DN 4929All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN 1237837All SZGR genes in this pathway
BILD_E2F3_ONCOGENIC_SIGNATURE 246153All SZGR genes in this pathway
HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_DN 281179All SZGR genes in this pathway
ACEVEDO_LIVER_CANCER_UP 973570All SZGR genes in this pathway
SMID_BREAST_CANCER_NORMAL_LIKE_UP 476285All SZGR genes in this pathway
QI_PLASMACYTOMA_UP 259185All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_DN 315201All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_HGF_DN 235144All SZGR genes in this pathway
RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_UP 408276All SZGR genes in this pathway
STAMBOLSKY_RESPONSE_TO_VITAMIN_D3_UP 8448All SZGR genes in this pathway
PILON_KLF1_TARGETS_DN 19721213All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_A 898516All SZGR genes in this pathway
ACEVEDO_FGFR1_TARGETS_IN_PROSTATE_CANCER_MODEL_UP 289184All SZGR genes in this pathway
GHANDHI_DIRECT_IRRADIATION_UP 11068All SZGR genes in this pathway
WARTERS_RESPONSE_TO_IR_SKIN 8344All SZGR genes in this pathway
WARTERS_IR_RESPONSE_5GY 4723All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-1451131201A,m8hsa-miR-145GUCCAGUUUUCCCAGGAAUCCCUU
miR-1811471541A,m8hsa-miR-181abrainAACAUUCAACGCUGUCGGUGAGU
hsa-miR-181bSZAACAUUCAUUGCUGUCGGUGGG
hsa-miR-181cbrainAACAUUCAACCUGUCGGUGAGU
hsa-miR-181dbrainAACAUUCAUUGUUGUCGGUGGGUU
miR-271431501A,m8hsa-miR-27abrainUUCACAGUGGCUAAGUUCCGC
hsa-miR-27bbrainUUCACAGUGGCUAAGUUCUGC
miR-3771691751Ahsa-miR-377AUCACACAAAGGCAACUUUUGU
miR-3812292351Ahsa-miR-381UAUACAAGGGCAAGCUCUCUGU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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