Summary ?
GeneID23233
SymbolEXOC6B
SynonymsSEC15B|SEC15L2
Descriptionexocyst complex component 6B
ReferenceMIM:607880|HGNC:HGNC:17085|Ensembl:ENSG00000144036|Vega:OTTHUMG00000152723
Gene typeprotein-coding
Map location2p13.2
Pascal p-value0.04
Sherlock p-value0.205
eGeneMyers' cis & trans
SupportG2Cdb.human_BAYES-COLLINS-HUMAN-PSD-FULL
G2Cdb.human_BAYES-COLLINS-MOUSE-PSD-CONSENSUS
Ascano FMRP targets

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs4634107chr3186341392EXOC6B232330.14trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
GenePearson's Correlation Spearman's Correlation
E2F50.880.85
HAUS10.880.88
CPSF30.870.84
UGDH0.870.82
MKI67IP0.870.85
C5orf540.870.86
CENPH0.870.85
CHIC20.870.82
KATNA10.860.86
SFRS30.860.83
Top 10 negatively co-expressed genes
GenePearson's Correlation Spearman's Correlation
HLA-F-0.62-0.73
AF347015.33-0.59-0.74
TINAGL1-0.58-0.73
PTH1R-0.57-0.70
CA4-0.57-0.69
AF347015.27-0.57-0.70
FBXO2-0.56-0.64
MT-CO2-0.56-0.70
MT-CYB-0.56-0.71
ATP10A-0.56-0.67

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
CORRE MULTIPLE MYELOMA UP 7445All SZGR 2.0 genes in this pathway
WANG LMO4 TARGETS DN 352225All SZGR 2.0 genes in this pathway
SU PANCREAS 5430All SZGR 2.0 genes in this pathway
MA PITUITARY FETAL VS ADULT DN 1917All SZGR 2.0 genes in this pathway
SU LIVER 5532All SZGR 2.0 genes in this pathway
BROWNE HCMV INFECTION 12HR DN 10164All SZGR 2.0 genes in this pathway
ZHENG BOUND BY FOXP3 491310All SZGR 2.0 genes in this pathway
ZHENG FOXP3 TARGETS IN THYMUS UP 196137All SZGR 2.0 genes in this pathway
BEIER GLIOMA STEM CELL DN 6642All SZGR 2.0 genes in this pathway
DUTERTRE ESTRADIOL RESPONSE 24HR DN 505328All SZGR 2.0 genes in this pathway
BRUINS UVC RESPONSE VIA TP53 GROUP D 280158All SZGR 2.0 genes in this pathway
ZWANG TRANSIENTLY UP BY 1ST EGF PULSE ONLY 1839928All SZGR 2.0 genes in this pathway