Gene Page: EXOC6B
Summary ?
GeneID | 23233 |
Symbol | EXOC6B |
Synonyms | SEC15B|SEC15L2 |
Description | exocyst complex component 6B |
Reference | MIM:607880|HGNC:HGNC:17085|Ensembl:ENSG00000144036|Vega:OTTHUMG00000152723 |
Gene type | protein-coding |
Map location | 2p13.2 |
Pascal p-value | 0.04 |
Sherlock p-value | 0.205 |
eGene | Myers' cis & trans |
Support | G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-FULL G2Cdb.human_BAYES-COLLINS-MOUSE-PSD-CONSENSUS Ascano FMRP targets |
Gene in Data Sources
Gene set name | Method of gene set | Description | Info |
---|---|---|---|
CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
eQTL annotation
SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
---|---|---|---|---|---|---|---|---|
rs4634107 | chr3 | 186341392 | EXOC6B | 23233 | 0.14 | trans |
Section II. Transcriptome annotation
General gene expression (GTEx)

Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
Top 10 positively co-expressed genes | ||
Gene | Pearson's Correlation | Spearman's Correlation |
E2F5 | 0.88 | 0.85 |
HAUS1 | 0.88 | 0.88 |
CPSF3 | 0.87 | 0.84 |
UGDH | 0.87 | 0.82 |
MKI67IP | 0.87 | 0.85 |
C5orf54 | 0.87 | 0.86 |
CENPH | 0.87 | 0.85 |
CHIC2 | 0.87 | 0.82 |
KATNA1 | 0.86 | 0.86 |
SFRS3 | 0.86 | 0.83 |
Top 10 negatively co-expressed genes | ||
Gene | Pearson's Correlation | Spearman's Correlation |
HLA-F | -0.62 | -0.73 |
AF347015.33 | -0.59 | -0.74 |
TINAGL1 | -0.58 | -0.73 |
PTH1R | -0.57 | -0.70 |
CA4 | -0.57 | -0.69 |
AF347015.27 | -0.57 | -0.70 |
FBXO2 | -0.56 | -0.64 |
MT-CO2 | -0.56 | -0.70 |
MT-CYB | -0.56 | -0.71 |
ATP10A | -0.56 | -0.67 |
Section V. Pathway annotation
Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
---|---|---|---|
CORRE MULTIPLE MYELOMA UP | 74 | 45 | All SZGR 2.0 genes in this pathway |
WANG LMO4 TARGETS DN | 352 | 225 | All SZGR 2.0 genes in this pathway |
SU PANCREAS | 54 | 30 | All SZGR 2.0 genes in this pathway |
MA PITUITARY FETAL VS ADULT DN | 19 | 17 | All SZGR 2.0 genes in this pathway |
SU LIVER | 55 | 32 | All SZGR 2.0 genes in this pathway |
BROWNE HCMV INFECTION 12HR DN | 101 | 64 | All SZGR 2.0 genes in this pathway |
ZHENG BOUND BY FOXP3 | 491 | 310 | All SZGR 2.0 genes in this pathway |
ZHENG FOXP3 TARGETS IN THYMUS UP | 196 | 137 | All SZGR 2.0 genes in this pathway |
BEIER GLIOMA STEM CELL DN | 66 | 42 | All SZGR 2.0 genes in this pathway |
DUTERTRE ESTRADIOL RESPONSE 24HR DN | 505 | 328 | All SZGR 2.0 genes in this pathway |
BRUINS UVC RESPONSE VIA TP53 GROUP D | 280 | 158 | All SZGR 2.0 genes in this pathway |
ZWANG TRANSIENTLY UP BY 1ST EGF PULSE ONLY | 1839 | 928 | All SZGR 2.0 genes in this pathway |