Summary ?
GeneID23295
SymbolMGRN1
SynonymsRNF156
Descriptionmahogunin ring finger 1, E3 ubiquitin protein ligase
ReferenceMIM:607559|HGNC:HGNC:20254|Ensembl:ENSG00000102858|HPRD:07397|Vega:OTTHUMG00000176436
Gene typeprotein-coding
Map location16p13.3
Pascal p-value0.002
Sherlock p-value0.87
Fetal beta0.541
DMG1 (# studies)
eGeneAnterior cingulate cortex BA24
Caudate basal ganglia
Cerebellar Hemisphere
Cerebellum
Cortex
Frontal Cortex BA9
Hippocampus
Hypothalamus
Nucleus accumbens basal ganglia
Putamen basal ganglia
Myers' cis & trans

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS
DMG:Montano_2016Genome-wide DNA methylation analysisThis dataset includes 172 replicated associations between CpGs with schizophrenia. 1

Section I. Genetics and epigenetics annotation

@Differentially methylated gene

ProbeChromosomePositionNearest geneP (dis)Beta (dis)FDR (dis)Study
cg04962621164714733MGRN11.32E-7-0.0090.01DMG:Montano_2016

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs2834904chr2136689995MGRN1232950.02trans
rs1684619164708523MGRN1ENSG00000102858.86.96E-9042029gtex_brain_ba24
rs72582364164708541MGRN1ENSG00000102858.86.288E-9042047gtex_brain_ba24
rs34636732164708542MGRN1ENSG00000102858.86.303E-9042048gtex_brain_ba24
rs1659500164708959MGRN1ENSG00000102858.88.156E-10042465gtex_brain_ba24
rs1659501164709131MGRN1ENSG00000102858.82.981E-9042637gtex_brain_ba24
rs1684620164709636MGRN1ENSG00000102858.81.817E-8043142gtex_brain_ba24
rs75130634164710779MGRN1ENSG00000102858.86.635E-9044285gtex_brain_ba24
rs1684623164711393MGRN1ENSG00000102858.89.825E-7044899gtex_brain_ba24
rs1684624164711737MGRN1ENSG00000102858.84.739E-9045243gtex_brain_ba24
rs1659503164711791MGRN1ENSG00000102858.84.522E-9045297gtex_brain_ba24
rs1684625164712148MGRN1ENSG00000102858.85.216E-9045654gtex_brain_ba24
rs12600113164712401MGRN1ENSG00000102858.81.097E-8045907gtex_brain_ba24
rs1659480164714365MGRN1ENSG00000102858.82.569E-9047871gtex_brain_ba24
rs1659479164714639MGRN1ENSG00000102858.81.424E-9048145gtex_brain_ba24
rs3813746164715012MGRN1ENSG00000102858.85.551E-8048518gtex_brain_ba24
rs59640193164716062MGRN1ENSG00000102858.81.015E-8049568gtex_brain_ba24
rs28448402164716103MGRN1ENSG00000102858.85.059E-9049609gtex_brain_ba24
rs57085123164716254MGRN1ENSG00000102858.81.036E-8049760gtex_brain_ba24
rs34069734164718388MGRN1ENSG00000102858.82.482E-7051894gtex_brain_ba24
rs56308101164718656MGRN1ENSG00000102858.81.414E-6052162gtex_brain_ba24
rs62037139164719349MGRN1ENSG00000102858.85.811E-8052855gtex_brain_ba24
rs715109164721468MGRN1ENSG00000102858.84.143E-8054974gtex_brain_ba24
rs1659494164722201MGRN1ENSG00000102858.82.257E-9055707gtex_brain_ba24
rs2289314164723451MGRN1ENSG00000102858.84.551E-8056957gtex_brain_ba24
rs12598162164724166MGRN1ENSG00000102858.88.937E-7057672gtex_brain_ba24
rs111273040164724665MGRN1ENSG00000102858.84.815E-7058171gtex_brain_ba24
rs2450390164725450MGRN1ENSG00000102858.83.847E-7058956gtex_brain_ba24
rs1659493164725863MGRN1ENSG00000102858.85.437E-7059369gtex_brain_ba24
rs1684605164726008MGRN1ENSG00000102858.86.626E-8059514gtex_brain_ba24
rs1684604164726451MGRN1ENSG00000102858.84.61E-7059957gtex_brain_ba24
rs3992629164728288MGRN1ENSG00000102858.82.812E-7061794gtex_brain_ba24
rs76906593164728291MGRN1ENSG00000102858.88.089E-8061797gtex_brain_ba24
rs1684603164728527MGRN1ENSG00000102858.84.525E-7062033gtex_brain_ba24
rs841229164731155MGRN1ENSG00000102858.84.125E-7064661gtex_brain_ba24
rs841228164733542MGRN1ENSG00000102858.81.235E-6067048gtex_brain_ba24
rs841227164734513MGRN1ENSG00000102858.81.101E-7068019gtex_brain_ba24
rs865775164735528MGRN1ENSG00000102858.82.774E-10069034gtex_brain_ba24
rs1684588164735631MGRN1ENSG00000102858.82.837E-10069137gtex_brain_ba24
rs200289286164736080MGRN1ENSG00000102858.82.772E-10069586gtex_brain_ba24
rs841225164736316MGRN1ENSG00000102858.85.629E-11069822gtex_brain_ba24
rs841224164736834MGRN1ENSG00000102858.81.538E-10070340gtex_brain_ba24
rs844488164737383MGRN1ENSG00000102858.81.826E-10070889gtex_brain_ba24
rs841223164737981MGRN1ENSG00000102858.86.395E-8071487gtex_brain_ba24
rs841222164738251MGRN1ENSG00000102858.83.81E-8071757gtex_brain_ba24
rs1684590164739514MGRN1ENSG00000102858.83.897E-7073020gtex_brain_ba24
rs3747592164740208MGRN1ENSG00000102858.89.004E-8073714gtex_brain_ba24
rs1045518164740441MGRN1ENSG00000102858.82.592E-8073947gtex_brain_ba24
rs1045519164740444MGRN1ENSG00000102858.89.56E-8073950gtex_brain_ba24
rs1045520164740477MGRN1ENSG00000102858.85.765E-8073983gtex_brain_ba24
rs841220164740602MGRN1ENSG00000102858.85.562E-8074108gtex_brain_ba24
rs841219164741636MGRN1ENSG00000102858.81.017E-7075142gtex_brain_ba24
rs841216164746829MGRN1ENSG00000102858.89.643E-8080335gtex_brain_ba24
rs841215164747136MGRN1ENSG00000102858.82.618E-7080642gtex_brain_ba24
rs74666947164749860MGRN1ENSG00000102858.84.804E-7083366gtex_brain_ba24
rs841212164749915MGRN1ENSG00000102858.88.605E-8083421gtex_brain_ba24
rs841211164750274MGRN1ENSG00000102858.84.846E-7083780gtex_brain_ba24
rs863980164751045MGRN1ENSG00000102858.83.604E-7084551gtex_brain_ba24
rs841210164752134MGRN1ENSG00000102858.82.547E-8085640gtex_brain_ba24
rs2404282164753624MGRN1ENSG00000102858.81.343E-6087130gtex_brain_ba24
rs78958044164753877MGRN1ENSG00000102858.84.197E-7087383gtex_brain_ba24
rs1684615164754194MGRN1ENSG00000102858.82.07E-7087700gtex_brain_ba24
rs1684584164758465MGRN1ENSG00000102858.84.193E-7091971gtex_brain_ba24
rs1684586164758897MGRN1ENSG00000102858.88.278E-7092403gtex_brain_ba24
rs57183997164761361MGRN1ENSG00000102858.81.417E-6094867gtex_brain_ba24
rs9921788164804490MGRN1ENSG00000102858.81.167E-60137996gtex_brain_ba24
rs4785974164804651MGRN1ENSG00000102858.81.646E-60138157gtex_brain_ba24
rs1684619164708523MGRN1ENSG00000102858.87.271E-9042029gtex_brain_putamen_basal
rs72582364164708541MGRN1ENSG00000102858.89.026E-8042047gtex_brain_putamen_basal
rs34636732164708542MGRN1ENSG00000102858.89.149E-8042048gtex_brain_putamen_basal
rs1659500164708959MGRN1ENSG00000102858.84.849E-8042465gtex_brain_putamen_basal
rs1659501164709131MGRN1ENSG00000102858.89.235E-8042637gtex_brain_putamen_basal
rs75130634164710779MGRN1ENSG00000102858.84.487E-7044285gtex_brain_putamen_basal
rs1684624164711737MGRN1ENSG00000102858.88.051E-8045243gtex_brain_putamen_basal
rs1659503164711791MGRN1ENSG00000102858.81.536E-8045297gtex_brain_putamen_basal
rs1684625164712148MGRN1ENSG00000102858.81.224E-8045654gtex_brain_putamen_basal
rs12600113164712401MGRN1ENSG00000102858.86.281E-7045907gtex_brain_putamen_basal
rs1659480164714365MGRN1ENSG00000102858.83.86E-8047871gtex_brain_putamen_basal
rs1659479164714639MGRN1ENSG00000102858.82.684E-8048145gtex_brain_putamen_basal
rs3813746164715012MGRN1ENSG00000102858.84.68E-8048518gtex_brain_putamen_basal
rs59640193164716062MGRN1ENSG00000102858.83.397E-7049568gtex_brain_putamen_basal
rs28448402164716103MGRN1ENSG00000102858.86.237E-9049609gtex_brain_putamen_basal
rs57085123164716254MGRN1ENSG00000102858.83.557E-7049760gtex_brain_putamen_basal
rs34069734164718388MGRN1ENSG00000102858.81.118E-7051894gtex_brain_putamen_basal
rs56308101164718656MGRN1ENSG00000102858.83.96E-7052162gtex_brain_putamen_basal
rs62037139164719349MGRN1ENSG00000102858.84.635E-7052855gtex_brain_putamen_basal
rs57385693164719459MGRN1ENSG00000102858.83.234E-7052965gtex_brain_putamen_basal
rs1659495164719981MGRN1ENSG00000102858.82.213E-6053487gtex_brain_putamen_basal
rs4786533164720390MGRN1ENSG00000102858.82.143E-6053896gtex_brain_putamen_basal
rs2278567164720993MGRN1ENSG00000102858.82.734E-7054499gtex_brain_putamen_basal
rs2278566164721025MGRN1ENSG00000102858.82.262E-7054531gtex_brain_putamen_basal
rs715109164721468MGRN1ENSG00000102858.84.346E-10054974gtex_brain_putamen_basal
rs1659494164722201MGRN1ENSG00000102858.88.387E-9055707gtex_brain_putamen_basal
rs2289314164723451MGRN1ENSG00000102858.81.763E-9056957gtex_brain_putamen_basal
rs12598162164724166MGRN1ENSG00000102858.83.399E-8057672gtex_brain_putamen_basal
rs12599757164724354MGRN1ENSG00000102858.83.346E-8057860gtex_brain_putamen_basal
rs111273040164724665MGRN1ENSG00000102858.81.174E-6058171gtex_brain_putamen_basal
rs2450390164725450MGRN1ENSG00000102858.82.077E-10058956gtex_brain_putamen_basal
rs1659493164725863MGRN1ENSG00000102858.81.931E-9059369gtex_brain_putamen_basal
rs1684605164726008MGRN1ENSG00000102858.85.464E-11059514gtex_brain_putamen_basal
rs1684604164726451MGRN1ENSG00000102858.81.997E-9059957gtex_brain_putamen_basal
rs3992629164728288MGRN1ENSG00000102858.81.357E-10061794gtex_brain_putamen_basal
rs76906593164728291MGRN1ENSG00000102858.81.056E-9061797gtex_brain_putamen_basal
rs1684603164728527MGRN1ENSG00000102858.81.467E-9062033gtex_brain_putamen_basal
rs841229164731155MGRN1ENSG00000102858.81.144E-10064661gtex_brain_putamen_basal
rs841228164733542MGRN1ENSG00000102858.84.435E-9067048gtex_brain_putamen_basal
rs841227164734513MGRN1ENSG00000102858.88.968E-9068019gtex_brain_putamen_basal
rs865775164735528MGRN1ENSG00000102858.84.244E-12069034gtex_brain_putamen_basal
rs1684588164735631MGRN1ENSG00000102858.84.289E-12069137gtex_brain_putamen_basal
rs200289286164736080MGRN1ENSG00000102858.87.482E-13069586gtex_brain_putamen_basal
rs841225164736316MGRN1ENSG00000102858.81.957E-13069822gtex_brain_putamen_basal
rs841224164736834MGRN1ENSG00000102858.88.473E-12070340gtex_brain_putamen_basal
rs844488164737383MGRN1ENSG00000102858.81.135E-12070889gtex_brain_putamen_basal
rs841223164737981MGRN1ENSG00000102858.85.956E-8071487gtex_brain_putamen_basal
rs841222164738251MGRN1ENSG00000102858.81.211E-7071757gtex_brain_putamen_basal
rs1684590164739514MGRN1ENSG00000102858.84.194E-9073020gtex_brain_putamen_basal
rs3747592164740208MGRN1ENSG00000102858.81.208E-11073714gtex_brain_putamen_basal
rs1045518164740441MGRN1ENSG00000102858.84.334E-10073947gtex_brain_putamen_basal
rs1045519164740444MGRN1ENSG00000102858.89.646E-11073950gtex_brain_putamen_basal
rs1045520164740477MGRN1ENSG00000102858.81.389E-9073983gtex_brain_putamen_basal
rs841220164740602MGRN1ENSG00000102858.82.374E-9074108gtex_brain_putamen_basal
rs841219164741636MGRN1ENSG00000102858.82.029E-11075142gtex_brain_putamen_basal
rs841218164742979MGRN1ENSG00000102858.86.801E-9076485gtex_brain_putamen_basal
rs841217164746392MGRN1ENSG00000102858.81.177E-7079898gtex_brain_putamen_basal
rs841216164746829MGRN1ENSG00000102858.84.746E-9080335gtex_brain_putamen_basal
rs841215164747136MGRN1ENSG00000102858.81.058E-7080642gtex_brain_putamen_basal
rs841214164748825MGRN1ENSG00000102858.89.194E-8082331gtex_brain_putamen_basal
rs74666947164749860MGRN1ENSG00000102858.81.666E-8083366gtex_brain_putamen_basal
rs841212164749915MGRN1ENSG00000102858.85.134E-9083421gtex_brain_putamen_basal
rs841211164750274MGRN1ENSG00000102858.81.662E-8083780gtex_brain_putamen_basal
rs863980164751045MGRN1ENSG00000102858.81.536E-8084551gtex_brain_putamen_basal
rs841210164752134MGRN1ENSG00000102858.81.062E-9085640gtex_brain_putamen_basal
rs2404282164753624MGRN1ENSG00000102858.82.825E-8087130gtex_brain_putamen_basal
rs78958044164753877MGRN1ENSG00000102858.82.429E-9087383gtex_brain_putamen_basal
rs1684615164754194MGRN1ENSG00000102858.86.176E-10087700gtex_brain_putamen_basal
rs1684616164755639MGRN1ENSG00000102858.85.121E-7089145gtex_brain_putamen_basal
rs1684617164756544MGRN1ENSG00000102858.81.177E-6090050gtex_brain_putamen_basal
rs1659492164757416MGRN1ENSG00000102858.81.714E-7090922gtex_brain_putamen_basal
rs1659491164757475MGRN1ENSG00000102858.81.717E-7090981gtex_brain_putamen_basal
rs1684584164758465MGRN1ENSG00000102858.87.614E-7091971gtex_brain_putamen_basal
rs1684586164758897MGRN1ENSG00000102858.81.768E-7092403gtex_brain_putamen_basal
rs1684587164759865MGRN1ENSG00000102858.81.794E-7093371gtex_brain_putamen_basal
rs28843142164761036MGRN1ENSG00000102858.88.97E-7094542gtex_brain_putamen_basal
rs57183997164761361MGRN1ENSG00000102858.81.421E-7094867gtex_brain_putamen_basal
rs859325164765948MGRN1ENSG00000102858.89.719E-7099454gtex_brain_putamen_basal
rs859326164766155MGRN1ENSG00000102858.82.294E-7099661gtex_brain_putamen_basal
rs859328164766326MGRN1ENSG00000102858.81.492E-7099832gtex_brain_putamen_basal
rs859295164771918MGRN1ENSG00000102858.83.212E-70105424gtex_brain_putamen_basal
rs703813164780696MGRN1ENSG00000102858.81.186E-60114202gtex_brain_putamen_basal
rs859323164781692MGRN1ENSG00000102858.81.715E-60115198gtex_brain_putamen_basal
rs859317164782875MGRN1ENSG00000102858.81.675E-60116381gtex_brain_putamen_basal
rs859315164785807MGRN1ENSG00000102858.81.845E-60119313gtex_brain_putamen_basal
rs4038772164786305MGRN1ENSG00000102858.81.905E-60119811gtex_brain_putamen_basal
rs2579667164788821MGRN1ENSG00000102858.82.129E-60122327gtex_brain_putamen_basal
rs2605572164788823MGRN1ENSG00000102858.82.129E-60122329gtex_brain_putamen_basal
rs2605573164789213MGRN1ENSG00000102858.82.144E-60122719gtex_brain_putamen_basal
rs397739237164793511MGRN1ENSG00000102858.84.438E-70127017gtex_brain_putamen_basal
rs2305657164793658MGRN1ENSG00000102858.83.38E-70127164gtex_brain_putamen_basal
rs1563444164794227MGRN1ENSG00000102858.83.613E-70127733gtex_brain_putamen_basal
rs2075469164794873MGRN1ENSG00000102858.81.52E-70128379gtex_brain_putamen_basal
rs2075470164795245MGRN1ENSG00000102858.82.123E-60128751gtex_brain_putamen_basal
rs2075471164795273MGRN1ENSG00000102858.83.596E-70128779gtex_brain_putamen_basal
rs741694164795554MGRN1ENSG00000102858.81.415E-60129060gtex_brain_putamen_basal
rs2341989164795892MGRN1ENSG00000102858.83.596E-70129398gtex_brain_putamen_basal
rs3888386164795908MGRN1ENSG00000102858.86.375E-80129414gtex_brain_putamen_basal
rs737698164796084MGRN1ENSG00000102858.83.872E-70129590gtex_brain_putamen_basal
rs737697164796192MGRN1ENSG00000102858.87.882E-80129698gtex_brain_putamen_basal
rs737700164796393MGRN1ENSG00000102858.87.882E-80129899gtex_brain_putamen_basal
rs759988164796595MGRN1ENSG00000102858.83.872E-70130101gtex_brain_putamen_basal
rs759989164797226MGRN1ENSG00000102858.81.625E-70130732gtex_brain_putamen_basal
rs17853375164797457MGRN1ENSG00000102858.81.181E-60130963gtex_brain_putamen_basal
rs59575807164797794MGRN1ENSG00000102858.81.472E-70131300gtex_brain_putamen_basal
rs2341987164798201MGRN1ENSG00000102858.82.123E-60131707gtex_brain_putamen_basal
rs2290560164799041MGRN1ENSG00000102858.81.625E-70132547gtex_brain_putamen_basal
rs12162062164800009MGRN1ENSG00000102858.83.872E-70133515gtex_brain_putamen_basal
rs11076845164801366MGRN1ENSG00000102858.87.519E-70134872gtex_brain_putamen_basal
rs921863164801723MGRN1ENSG00000102858.83.02E-70135229gtex_brain_putamen_basal
rs921864164801842MGRN1ENSG00000102858.82.224E-60135348gtex_brain_putamen_basal
rs3747601164802370MGRN1ENSG00000102858.83.887E-70135876gtex_brain_putamen_basal
rs3747602164802386MGRN1ENSG00000102858.85.813E-70135892gtex_brain_putamen_basal
rs963712164803327MGRN1ENSG00000102858.81.729E-60136833gtex_brain_putamen_basal
rs9921788164804490MGRN1ENSG00000102858.84.634E-70137996gtex_brain_putamen_basal
rs4785974164804651MGRN1ENSG00000102858.82.086E-70138157gtex_brain_putamen_basal
rs9937064164806185MGRN1ENSG00000102858.84.2E-70139691gtex_brain_putamen_basal
rs72770396164806388MGRN1ENSG00000102858.81.171E-60139894gtex_brain_putamen_basal
rs2085330164807064MGRN1ENSG00000102858.89.322E-70140570gtex_brain_putamen_basal
rs2061212164807403MGRN1ENSG00000102858.88.581E-70140909gtex_brain_putamen_basal
rs9921524164807751MGRN1ENSG00000102858.87.05E-70141257gtex_brain_putamen_basal
rs9935103164808260MGRN1ENSG00000102858.87.163E-70141766gtex_brain_putamen_basal
rs3747603164808523MGRN1ENSG00000102858.87.868E-70142029gtex_brain_putamen_basal
rs34448916164808911MGRN1ENSG00000102858.81.456E-60142417gtex_brain_putamen_basal
rs9673738164809008MGRN1ENSG00000102858.87.32E-70142514gtex_brain_putamen_basal
rs62036067164809734MGRN1ENSG00000102858.81.181E-60143240gtex_brain_putamen_basal
rs66507473164809804MGRN1ENSG00000102858.81.181E-60143310gtex_brain_putamen_basal
rs9936227164811179MGRN1ENSG00000102858.86.224E-80144685gtex_brain_putamen_basal
rs12599765164812209MGRN1ENSG00000102858.82.086E-70145715gtex_brain_putamen_basal
rs4786546164814767MGRN1ENSG00000102858.81.452E-60148273gtex_brain_putamen_basal

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
GenePearson's Correlation Spearman's Correlation
C5orf320.830.85
TNFSF120.830.82
BDH10.830.83
GNPTG0.820.86
CA110.810.85
SHISA40.800.82
DHX580.800.80
GCAT0.800.79
ANGPTL60.790.82
SULT1A10.790.78
Top 10 negatively co-expressed genes
GenePearson's Correlation Spearman's Correlation
KIAA1949-0.70-0.59
ZNF551-0.67-0.61
TUBB2B-0.67-0.59
THOC2-0.67-0.71
AC004017.1-0.67-0.61
ZNF311-0.67-0.59
ZNF193-0.66-0.61
FNBP1L-0.66-0.60
ZNF300-0.66-0.58
SETDB1-0.66-0.57

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
KEGG UBIQUITIN MEDIATED PROTEOLYSIS 13898All SZGR 2.0 genes in this pathway
WATANABE RECTAL CANCER RADIOTHERAPY RESPONSIVE UP 10867All SZGR 2.0 genes in this pathway
CHARAFE BREAST CANCER LUMINAL VS BASAL UP 380215All SZGR 2.0 genes in this pathway
TIEN INTESTINE PROBIOTICS 24HR UP 557331All SZGR 2.0 genes in this pathway
DELYS THYROID CANCER UP 443294All SZGR 2.0 genes in this pathway
DASU IL6 SIGNALING SCAR UP 3021All SZGR 2.0 genes in this pathway
BROWNE HCMV INFECTION 48HR DN 504323All SZGR 2.0 genes in this pathway
AMBROSINI FLAVOPIRIDOL TREATMENT TP53 10963All SZGR 2.0 genes in this pathway
ACEVEDO NORMAL TISSUE ADJACENT TO LIVER TUMOR DN 354216All SZGR 2.0 genes in this pathway
DASU IL6 SIGNALING UP 5944All SZGR 2.0 genes in this pathway
BROWNE HCMV INFECTION 1HR DN 222147All SZGR 2.0 genes in this pathway
KIM ALL DISORDERS OLIGODENDROCYTE NUMBER CORR UP 756494All SZGR 2.0 genes in this pathway
WAKABAYASHI ADIPOGENESIS PPARG BOUND 8D 658397All SZGR 2.0 genes in this pathway
FORTSCHEGGER PHF8 TARGETS DN 784464All SZGR 2.0 genes in this pathway