Gene Page: NUDCD3
Summary ?
| GeneID | 23386 |
| Symbol | NUDCD3 |
| Synonyms | NudCL |
| Description | NudC domain containing 3 |
| Reference | MIM:610296|HGNC:HGNC:22208|HPRD:13831| |
| Gene type | protein-coding |
| Map location | 7p13-p12 |
| Pascal p-value | 0.001 |
| Sherlock p-value | 0.286 |
| eGene | Cerebellum |
| Support | Ascano FMRP targets |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| LASS2 | 0.86 | 0.81 |
| GLTP | 0.85 | 0.83 |
| RHOG | 0.85 | 0.83 |
| TTYH2 | 0.83 | 0.82 |
| HSPA2 | 0.83 | 0.83 |
| TF | 0.83 | 0.77 |
| KLK6 | 0.83 | 0.74 |
| FA2H | 0.82 | 0.79 |
| SGK2 | 0.82 | 0.77 |
| GJB1 | 0.82 | 0.72 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| KLHL1 | -0.46 | -0.51 |
| PPAPR5 | -0.45 | -0.51 |
| STMN2 | -0.45 | -0.50 |
| GPRIN1 | -0.44 | -0.48 |
| MPPED1 | -0.43 | -0.48 |
| GPM6A | -0.43 | -0.54 |
| STMN1 | -0.43 | -0.50 |
| RPRM | -0.43 | -0.53 |
| MARCH4 | -0.43 | -0.46 |
| KIF21B | -0.43 | -0.46 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| LINDGREN BLADDER CANCER CLUSTER 2A DN | 141 | 84 | All SZGR 2.0 genes in this pathway |
| GRAESSMANN APOPTOSIS BY DOXORUBICIN DN | 1781 | 1082 | All SZGR 2.0 genes in this pathway |
| LINDGREN BLADDER CANCER WITH LOH IN CHR9Q | 116 | 71 | All SZGR 2.0 genes in this pathway |
| LOPEZ MBD TARGETS | 957 | 597 | All SZGR 2.0 genes in this pathway |
| ZHENG BOUND BY FOXP3 | 491 | 310 | All SZGR 2.0 genes in this pathway |
| ZHENG FOXP3 TARGETS IN THYMUS UP | 196 | 137 | All SZGR 2.0 genes in this pathway |
| IWANAGA CARCINOGENESIS BY KRAS DN | 120 | 81 | All SZGR 2.0 genes in this pathway |
| CHUNG BLISTER CYTOTOXICITY UP | 134 | 84 | All SZGR 2.0 genes in this pathway |
| HAN SATB1 TARGETS UP | 395 | 249 | All SZGR 2.0 genes in this pathway |
| YAGI AML WITH T 8 21 TRANSLOCATION | 368 | 247 | All SZGR 2.0 genes in this pathway |
| LU EZH2 TARGETS UP | 295 | 155 | All SZGR 2.0 genes in this pathway |
| KOINUMA TARGETS OF SMAD2 OR SMAD3 | 824 | 528 | All SZGR 2.0 genes in this pathway |
| ZWANG TRANSIENTLY UP BY 1ST EGF PULSE ONLY | 1839 | 928 | All SZGR 2.0 genes in this pathway |