Gene Page: CTDNEP1
Summary ?
| GeneID | 23399 |
| Symbol | CTDNEP1 |
| Synonyms | DULLARD|HSA011916|NET56 |
| Description | CTD nuclear envelope phosphatase 1 |
| Reference | MIM:610684|HGNC:HGNC:19085|Ensembl:ENSG00000175826|HPRD:16845|Vega:OTTHUMG00000102180 |
| Gene type | protein-coding |
| Map location | 17p13 |
| Pascal p-value | 2.439E-4 |
| eGene | Myers' cis & trans |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
eQTL annotation
| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs4587148 | chr6 | 161805706 | CTDNEP1 | 23399 | 0.2 | trans |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| ATP6V0C | 0.93 | 0.96 |
| TMEM59L | 0.93 | 0.94 |
| NRSN2 | 0.92 | 0.95 |
| AP001107.1 | 0.92 | 0.95 |
| SLC25A22 | 0.91 | 0.90 |
| SLC22A17 | 0.91 | 0.94 |
| ENTPD6 | 0.90 | 0.92 |
| IGSF8 | 0.90 | 0.90 |
| SH3BP1 | 0.90 | 0.93 |
| PINK1 | 0.90 | 0.90 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| EIF5B | -0.48 | -0.54 |
| AC005921.3 | -0.46 | -0.62 |
| NSBP1 | -0.44 | -0.44 |
| AF347015.18 | -0.43 | -0.26 |
| AC010300.1 | -0.43 | -0.44 |
| RBMX2 | -0.42 | -0.45 |
| KCNMB3 | -0.42 | -0.41 |
| AF347015.21 | -0.40 | -0.19 |
| IFI44 | -0.40 | -0.48 |
| C21orf57 | -0.40 | -0.37 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| PARENT MTOR SIGNALING UP | 567 | 375 | All SZGR 2.0 genes in this pathway |
| LASTOWSKA NEUROBLASTOMA COPY NUMBER UP | 181 | 108 | All SZGR 2.0 genes in this pathway |
| CHAUHAN RESPONSE TO METHOXYESTRADIOL DN | 102 | 65 | All SZGR 2.0 genes in this pathway |
| KIM ALL DISORDERS OLIGODENDROCYTE NUMBER CORR UP | 756 | 494 | All SZGR 2.0 genes in this pathway |
| KIM ALL DISORDERS DURATION CORR DN | 146 | 90 | All SZGR 2.0 genes in this pathway |