Gene Page: RHOQ
Summary ?
| GeneID | 23433 |
| Symbol | RHOQ |
| Synonyms | ARHQ|HEL-S-42|RASL7A|TC10|TC10A |
| Description | ras homolog family member Q |
| Reference | MIM:605857|HGNC:HGNC:17736|HPRD:05791| |
| Gene type | protein-coding |
| Map location | 2p21 |
| Pascal p-value | 0.042 |
| eGene | Myers' cis & trans |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
eQTL annotation
| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs10006027 | chr4 | 21631107 | RHOQ | 23433 | 0.19 | trans |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
No co-expressed genes in brain regions
Section IV. Protein-protein interaction annotation
| Interactors | Aliases B | Official full name B | Experimental | Source | PubMed ID |
|---|---|---|---|---|---|
| CDC42BPG | DMPK2 | HSMDPKIN | KAPPA-200 | MRCKgamma | CDC42 binding protein kinase gamma (DMPK-like) | Reconstituted Complex | BioGRID | 15194684 |
| CDC42EP1 | BORG5 | CEP1 | MGC15316 | MSE55 | CDC42 effector protein (Rho GTPase binding) 1 | - | HPRD,BioGRID | 10490598 |
| CDC42EP2 | BORG1 | CEP2 | CDC42 effector protein (Rho GTPase binding) 2 | in vitro Two-hybrid | BioGRID | 10490598 |
| CDC42EP2 | BORG1 | CEP2 | CDC42 effector protein (Rho GTPase binding) 2 | Activated TC10 interacts with Borg1. | BIND | 10490598 |
| CDC42EP3 | BORG2 | CEP3 | FLJ46903 | UB1 | CDC42 effector protein (Rho GTPase binding) 3 | Activated TC10 interacts with Borg2. | BIND | 10490598 |
| CDC42EP3 | BORG2 | CEP3 | FLJ46903 | UB1 | CDC42 effector protein (Rho GTPase binding) 3 | - | HPRD,BioGRID | 10490598 |
| CDC42EP4 | BORG4 | CEP4 | KAIA1777 | MGC17125 | MGC3740 | CDC42 effector protein (Rho GTPase binding) 4 | - | HPRD,BioGRID | 10490598 |
| COPB1 | COPB | DKFZp761K102 | FLJ10341 | coatomer protein complex, subunit beta 1 | - | HPRD | 12134073 |
| DOCK8 | FLJ00026 | FLJ00152 | FLJ00346 | MRD2 | ZIR8 | dedicator of cytokinesis 8 | - | HPRD,BioGRID | 15304341 |
| EXOC7 | 2-5-3p | DKFZp686J04253 | EX070 | EXO70 | EXOC1 | Exo70p | FLJ40965 | FLJ46415 | YJL085W | exocyst complex component 7 | - | HPRD,BioGRID | 12687004 |
| GOPC | CAL | FIG | GOPC1 | PIST | dJ94G16.2 | golgi associated PDZ and coiled-coil motif containing | - | HPRD,BioGRID | 11162552 |
| PARD6A | PAR-6A | PAR6 | PAR6C | PAR6alpha | TAX40 | TIP-40 | par-6 partitioning defective 6 homolog alpha (C. elegans) | Two-hybrid | BioGRID | 10934474 |
| PARD6B | PAR6B | par-6 partitioning defective 6 homolog beta (C. elegans) | Reconstituted Complex Two-hybrid | BioGRID | 10934474 |11162552 |
| PFN1 | - | profilin 1 | - | HPRD,BioGRID | 10445846 |
| TRIP10 | CIP4 | HSTP | STOT | STP | thyroid hormone receptor interactor 10 | - | HPRD,BioGRID | 12242347 |
| WAS | IMD2 | THC | WASP | Wiskott-Aldrich syndrome (eczema-thrombocytopenia) | TC10 interacts with WASP. | BIND | 15361624 |
| WASL | DKFZp779G0847 | MGC48327 | N-WASP | NWASP | Wiskott-Aldrich syndrome-like | - | HPRD,BioGRID | 12456725 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| KEGG INSULIN SIGNALING PATHWAY | 137 | 103 | All SZGR 2.0 genes in this pathway |
| PID INSULIN PATHWAY | 45 | 32 | All SZGR 2.0 genes in this pathway |
| PID INSULIN GLUCOSE PATHWAY | 26 | 24 | All SZGR 2.0 genes in this pathway |
| REACTOME SIGNALING BY RHO GTPASES | 113 | 81 | All SZGR 2.0 genes in this pathway |
| FULCHER INFLAMMATORY RESPONSE LECTIN VS LPS UP | 579 | 346 | All SZGR 2.0 genes in this pathway |
| LIU VMYB TARGETS UP | 127 | 78 | All SZGR 2.0 genes in this pathway |
| WANG LMO4 TARGETS UP | 372 | 227 | All SZGR 2.0 genes in this pathway |
| OSMAN BLADDER CANCER UP | 404 | 246 | All SZGR 2.0 genes in this pathway |
| OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL UP | 233 | 161 | All SZGR 2.0 genes in this pathway |
| TONKS TARGETS OF RUNX1 RUNX1T1 FUSION ERYTHROCYTE UP | 157 | 104 | All SZGR 2.0 genes in this pathway |
| UDAYAKUMAR MED1 TARGETS UP | 135 | 82 | All SZGR 2.0 genes in this pathway |
| KIM WT1 TARGETS 8HR UP | 164 | 122 | All SZGR 2.0 genes in this pathway |
| KIM WT1 TARGETS 12HR UP | 162 | 116 | All SZGR 2.0 genes in this pathway |
| WAMUNYOKOLI OVARIAN CANCER GRADES 1 2 DN | 67 | 43 | All SZGR 2.0 genes in this pathway |
| GOZGIT ESR1 TARGETS DN | 781 | 465 | All SZGR 2.0 genes in this pathway |
| COLDREN GEFITINIB RESISTANCE UP | 85 | 57 | All SZGR 2.0 genes in this pathway |
| PATIL LIVER CANCER | 747 | 453 | All SZGR 2.0 genes in this pathway |
| MOHANKUMAR TLX1 TARGETS UP | 414 | 287 | All SZGR 2.0 genes in this pathway |
| SPIELMAN LYMPHOBLAST EUROPEAN VS ASIAN DN | 584 | 395 | All SZGR 2.0 genes in this pathway |
| NUYTTEN EZH2 TARGETS UP | 1037 | 673 | All SZGR 2.0 genes in this pathway |
| BUYTAERT PHOTODYNAMIC THERAPY STRESS UP | 811 | 508 | All SZGR 2.0 genes in this pathway |
| WEI MIR34A TARGETS | 148 | 97 | All SZGR 2.0 genes in this pathway |
| MORI PRE BI LYMPHOCYTE DN | 77 | 49 | All SZGR 2.0 genes in this pathway |
| MORI IMMATURE B LYMPHOCYTE UP | 53 | 35 | All SZGR 2.0 genes in this pathway |
| BLALOCK ALZHEIMERS DISEASE INCIPIENT UP | 390 | 242 | All SZGR 2.0 genes in this pathway |
| IVANOVA HEMATOPOIESIS STEM CELL LONG TERM | 302 | 191 | All SZGR 2.0 genes in this pathway |
| BLALOCK ALZHEIMERS DISEASE UP | 1691 | 1088 | All SZGR 2.0 genes in this pathway |
| BROWNE HCMV INFECTION 48HR DN | 504 | 323 | All SZGR 2.0 genes in this pathway |
| VERRECCHIA EARLY RESPONSE TO TGFB1 | 58 | 43 | All SZGR 2.0 genes in this pathway |
| KAAB HEART ATRIUM VS VENTRICLE DN | 261 | 183 | All SZGR 2.0 genes in this pathway |
| XU GH1 AUTOCRINE TARGETS DN | 142 | 94 | All SZGR 2.0 genes in this pathway |
| VERRECCHIA RESPONSE TO TGFB1 C3 | 14 | 10 | All SZGR 2.0 genes in this pathway |
| CREIGHTON ENDOCRINE THERAPY RESISTANCE 4 | 307 | 185 | All SZGR 2.0 genes in this pathway |
| STEIN ESRRA TARGETS UP | 388 | 234 | All SZGR 2.0 genes in this pathway |
| GRADE COLON VS RECTAL CANCER UP | 38 | 21 | All SZGR 2.0 genes in this pathway |
| GOLDRATH ANTIGEN RESPONSE | 346 | 192 | All SZGR 2.0 genes in this pathway |
| RUTELLA RESPONSE TO CSF2RB AND IL4 DN | 315 | 201 | All SZGR 2.0 genes in this pathway |
| RUTELLA RESPONSE TO HGF UP | 418 | 282 | All SZGR 2.0 genes in this pathway |
| RUTELLA RESPONSE TO HGF VS CSF2RB AND IL4 UP | 408 | 276 | All SZGR 2.0 genes in this pathway |
| SHEDDEN LUNG CANCER GOOD SURVIVAL A12 | 317 | 177 | All SZGR 2.0 genes in this pathway |
| STEIN ESRRA TARGETS | 535 | 325 | All SZGR 2.0 genes in this pathway |
| WONG ADULT TISSUE STEM MODULE | 721 | 492 | All SZGR 2.0 genes in this pathway |
| YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 0 | 76 | 54 | All SZGR 2.0 genes in this pathway |
| CHYLA CBFA2T3 TARGETS UP | 387 | 225 | All SZGR 2.0 genes in this pathway |
| ZHU SKIL TARGETS UP | 20 | 14 | All SZGR 2.0 genes in this pathway |
| DELACROIX RARG BOUND MEF | 367 | 231 | All SZGR 2.0 genes in this pathway |
| DELACROIX RAR BOUND ES | 462 | 273 | All SZGR 2.0 genes in this pathway |
| PHONG TNF RESPONSE VIA P38 COMPLETE | 227 | 151 | All SZGR 2.0 genes in this pathway |