Gene Page: FUT1
Summary ?
| GeneID | 2523 |
| Symbol | FUT1 |
| Synonyms | H|HH|HSC |
| Description | fucosyltransferase 1 (H blood group) |
| Reference | MIM:211100|HGNC:HGNC:4012|Ensembl:ENSG00000174951|HPRD:07186|Vega:OTTHUMG00000183325 |
| Gene type | protein-coding |
| Map location | 19q13.3 |
| Pascal p-value | 5.172E-4 |
| Sherlock p-value | 0.095 |
| eGene | Myers' cis & trans |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
eQTL annotation
| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs9564096 | chr13 | 64288758 | FUT1 | 2523 | 0.08 | trans | ||
| rs9571014 | chr13 | 64303535 | FUT1 | 2523 | 0.18 | trans |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression during devlopment (BrainCloud)
Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| ZNF574 | 0.93 | 0.93 |
| USP19 | 0.92 | 0.93 |
| VARS | 0.92 | 0.93 |
| TRAF7 | 0.92 | 0.90 |
| TKT | 0.92 | 0.92 |
| XAB2 | 0.91 | 0.93 |
| RAB11B | 0.91 | 0.92 |
| DGCR14 | 0.91 | 0.91 |
| GGA1 | 0.91 | 0.92 |
| ARMC6 | 0.91 | 0.86 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| AF347015.31 | -0.76 | -0.86 |
| MT-CO2 | -0.74 | -0.86 |
| AF347015.27 | -0.73 | -0.85 |
| MT-CYB | -0.72 | -0.83 |
| AF347015.21 | -0.71 | -0.90 |
| AF347015.33 | -0.71 | -0.81 |
| AF347015.8 | -0.71 | -0.84 |
| C5orf53 | -0.68 | -0.71 |
| AF347015.15 | -0.67 | -0.81 |
| IFI27 | -0.67 | -0.77 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| KEGG GLYCOSPHINGOLIPID BIOSYNTHESIS LACTO AND NEOLACTO SERIES | 26 | 19 | All SZGR 2.0 genes in this pathway |
| KEGG GLYCOSPHINGOLIPID BIOSYNTHESIS GLOBO SERIES | 14 | 12 | All SZGR 2.0 genes in this pathway |
| CHARAFE BREAST CANCER LUMINAL VS MESENCHYMAL UP | 450 | 256 | All SZGR 2.0 genes in this pathway |
| WANG ESOPHAGUS CANCER VS NORMAL DN | 101 | 66 | All SZGR 2.0 genes in this pathway |
| PEREZ TP53 TARGETS | 1174 | 695 | All SZGR 2.0 genes in this pathway |
| SHETH LIVER CANCER VS TXNIP LOSS PAM5 | 94 | 59 | All SZGR 2.0 genes in this pathway |
| NUYTTEN EZH2 TARGETS DN | 1024 | 594 | All SZGR 2.0 genes in this pathway |
| LIN SILENCED BY TUMOR MICROENVIRONMENT | 108 | 73 | All SZGR 2.0 genes in this pathway |
| SHIPP DLBCL CURED VS FATAL UP | 39 | 22 | All SZGR 2.0 genes in this pathway |
| FERNANDEZ BOUND BY MYC | 182 | 116 | All SZGR 2.0 genes in this pathway |
| CUI GLUCOSE DEPRIVATION | 60 | 44 | All SZGR 2.0 genes in this pathway |
| YOSHIMURA MAPK8 TARGETS UP | 1305 | 895 | All SZGR 2.0 genes in this pathway |
| AGUIRRE PANCREATIC CANCER COPY NUMBER UP | 298 | 174 | All SZGR 2.0 genes in this pathway |
| MIKKELSEN MCV6 ICP WITH H3K27ME3 | 74 | 46 | All SZGR 2.0 genes in this pathway |
| DANG BOUND BY MYC | 1103 | 714 | All SZGR 2.0 genes in this pathway |
| MIKKELSEN ES ICP WITH H3K4ME3 | 718 | 401 | All SZGR 2.0 genes in this pathway |
| MARTENS TRETINOIN RESPONSE DN | 841 | 431 | All SZGR 2.0 genes in this pathway |
| PURBEY TARGETS OF CTBP1 NOT SATB1 DN | 448 | 282 | All SZGR 2.0 genes in this pathway |