Gene Page: ZNF620
Summary ?
| GeneID | 253639 |
| Symbol | ZNF620 |
| Synonyms | - |
| Description | zinc finger protein 620 |
| Reference | HGNC:HGNC:28742|Ensembl:ENSG00000177842|HPRD:15878|Vega:OTTHUMG00000156044 |
| Gene type | protein-coding |
| Map location | 3p22.1 |
| Pascal p-value | 0.585 |
| Sherlock p-value | 0.498 |
| Fetal beta | 0.992 |
| DMG | 1 (# studies) |
| eGene | Myers' cis & trans |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| DMG:Wockner_2014 | Genome-wide DNA methylation analysis | This dataset includes 4641 differentially methylated probes corresponding to 2929 unique genes between schizophrenia patients (n=24) and controls (n=24). | 1 |
Section I. Genetics and epigenetics annotation
Differentially methylated gene
| Probe | Chromosome | Position | Nearest gene | P (dis) | Beta (dis) | FDR (dis) | Study |
|---|---|---|---|---|---|---|---|
| cg13461273 | 3 | 40547232 | ZNF620 | 1.537E-4 | 0.438 | 0.032 | DMG:Wockner_2014 |
eQTL annotation
| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs2716734 | chr2 | 39947720 | ZNF620 | 253639 | 0.1 | trans | ||
| rs2716736 | chr2 | 39947946 | ZNF620 | 253639 | 0.1 | trans | ||
| snp_a-2169623 | 0 | ZNF620 | 253639 | 0.03 | trans |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression during devlopment (BrainCloud)
Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
No co-expressed genes in brain regions
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| REACTOME GENERIC TRANSCRIPTION PATHWAY | 352 | 181 | All SZGR 2.0 genes in this pathway |