Gene Page: NAPSB
Summary ?
| GeneID | 256236 |
| Symbol | NAPSB |
| Synonyms | NAP1L|NAP2|NAPB|NAPSBP |
| Description | napsin B aspartic peptidase, pseudogene |
| Reference | HGNC:HGNC:13396|Ensembl:ENSG00000131401| |
| Gene type | pseudo |
| Map location | 19q13.33 |
| Pascal p-value | 0.013 |
| Sherlock p-value | 0.895 |
| eGene | Caudate basal ganglia Cerebellar Hemisphere Cerebellum Cortex Frontal Cortex BA9 Hippocampus Hypothalamus Nucleus accumbens basal ganglia Putamen basal ganglia Meta |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
eQTL annotation
| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs60182980 | 19 | 50845704 | NAPSB | ENSG00000131401.7 | 4.765E-11 | 0 | 2320 | gtex_brain_putamen_basal |
| rs35522855 | 19 | 50846561 | NAPSB | ENSG00000131401.7 | 1.211E-11 | 0 | 1463 | gtex_brain_putamen_basal |
| rs201118502 | 19 | 50847032 | NAPSB | ENSG00000131401.7 | 6.273E-7 | 0 | 992 | gtex_brain_putamen_basal |
| rs530254097 | 19 | 50847033 | NAPSB | ENSG00000131401.7 | 6.968E-7 | 0 | 991 | gtex_brain_putamen_basal |
| rs11356463 | 19 | 50847034 | NAPSB | ENSG00000131401.7 | 7.42E-7 | 0 | 990 | gtex_brain_putamen_basal |
| rs59323905 | 19 | 50848025 | NAPSB | ENSG00000131401.7 | 8.091E-12 | 0 | -1 | gtex_brain_putamen_basal |
| rs4802696 | 19 | 50849211 | NAPSB | ENSG00000131401.7 | 7.25E-12 | 0 | -1187 | gtex_brain_putamen_basal |
| rs7246600 | 19 | 50851055 | NAPSB | ENSG00000131401.7 | 7.989E-12 | 0 | -3031 | gtex_brain_putamen_basal |
| rs35028989 | 19 | 50851934 | NAPSB | ENSG00000131401.7 | 8.516E-12 | 0 | -3910 | gtex_brain_putamen_basal |
| rs610363 | 19 | 50852244 | NAPSB | ENSG00000131401.7 | 1.46E-6 | 0 | -4220 | gtex_brain_putamen_basal |
| rs57887481 | 19 | 50852830 | NAPSB | ENSG00000131401.7 | 4.264E-7 | 0 | -4806 | gtex_brain_putamen_basal |
| rs586705 | 19 | 50853045 | NAPSB | ENSG00000131401.7 | 1.497E-6 | 0 | -5021 | gtex_brain_putamen_basal |
| rs583954 | 19 | 50853680 | NAPSB | ENSG00000131401.7 | 1.449E-11 | 0 | -5656 | gtex_brain_putamen_basal |
| rs656844 | 19 | 50855400 | NAPSB | ENSG00000131401.7 | 1.583E-6 | 0 | -7376 | gtex_brain_putamen_basal |
| rs643786 | 19 | 50855949 | NAPSB | ENSG00000131401.7 | 1.583E-6 | 0 | -7925 | gtex_brain_putamen_basal |
| rs71355141 | 19 | 50858019 | NAPSB | ENSG00000131401.7 | 4.034E-10 | 0 | -9995 | gtex_brain_putamen_basal |
| rs638294 | 19 | 50863023 | NAPSB | ENSG00000131401.7 | 4.512E-10 | 0 | -14999 | gtex_brain_putamen_basal |
| rs34541118 | 19 | 50864721 | NAPSB | ENSG00000131401.7 | 2.133E-11 | 0 | -16697 | gtex_brain_putamen_basal |
| rs676314 | 19 | 50865535 | NAPSB | ENSG00000131401.7 | 1.224E-10 | 0 | -17511 | gtex_brain_putamen_basal |
| rs61351775 | 19 | 50866884 | NAPSB | ENSG00000131401.7 | 1.224E-10 | 0 | -18860 | gtex_brain_putamen_basal |
| rs60132559 | 19 | 50867106 | NAPSB | ENSG00000131401.7 | 1.224E-10 | 0 | -19082 | gtex_brain_putamen_basal |
| rs8108875 | 19 | 50867492 | NAPSB | ENSG00000131401.7 | 1.224E-10 | 0 | -19468 | gtex_brain_putamen_basal |
| rs599100 | 19 | 50867729 | NAPSB | ENSG00000131401.7 | 9.753E-11 | 0 | -19705 | gtex_brain_putamen_basal |
| rs200434077 | 19 | 50868272 | NAPSB | ENSG00000131401.7 | 4.29E-7 | 0 | -20248 | gtex_brain_putamen_basal |
| rs1274517 | 19 | 50868754 | NAPSB | ENSG00000131401.7 | 1.224E-10 | 0 | -20730 | gtex_brain_putamen_basal |
| rs60930348 | 19 | 50870793 | NAPSB | ENSG00000131401.7 | 4.064E-11 | 0 | -22769 | gtex_brain_putamen_basal |
| rs1274514 | 19 | 50871147 | NAPSB | ENSG00000131401.7 | 1.224E-10 | 0 | -23123 | gtex_brain_putamen_basal |
| rs11879501 | 19 | 50872118 | NAPSB | ENSG00000131401.7 | 1.24E-10 | 0 | -24094 | gtex_brain_putamen_basal |
| rs1274513 | 19 | 50872719 | NAPSB | ENSG00000131401.7 | 8.52E-9 | 0 | -24695 | gtex_brain_putamen_basal |
| rs7247907 | 19 | 50874162 | NAPSB | ENSG00000131401.7 | 1.472E-10 | 0 | -26138 | gtex_brain_putamen_basal |
| rs35617599 | 19 | 50874794 | NAPSB | ENSG00000131401.7 | 1.487E-10 | 0 | -26770 | gtex_brain_putamen_basal |
| rs1274510 | 19 | 50875685 | NAPSB | ENSG00000131401.7 | 1.136E-8 | 0 | -27661 | gtex_brain_putamen_basal |
| rs35074450 | 19 | 50875746 | NAPSB | ENSG00000131401.7 | 1.052E-8 | 0 | -27722 | gtex_brain_putamen_basal |
| rs12985105 | 19 | 50877014 | NAPSB | ENSG00000131401.7 | 1.329E-10 | 0 | -28990 | gtex_brain_putamen_basal |
| rs35463555 | 19 | 50877680 | NAPSB | ENSG00000131401.7 | 1.378E-10 | 0 | -29656 | gtex_brain_putamen_basal |
| rs12972221 | 19 | 50879140 | NAPSB | ENSG00000131401.7 | 1.496E-10 | 0 | -31116 | gtex_brain_putamen_basal |
| rs17373080 | 19 | 50879524 | NAPSB | ENSG00000131401.7 | 1.535E-10 | 0 | -31500 | gtex_brain_putamen_basal |
| rs11880305 | 19 | 50880475 | NAPSB | ENSG00000131401.7 | 1.44E-10 | 0 | -32451 | gtex_brain_putamen_basal |
| rs28514894 | 19 | 50881326 | NAPSB | ENSG00000131401.7 | 1.406E-8 | 0 | -33302 | gtex_brain_putamen_basal |
| rs41432149 | 19 | 50882172 | NAPSB | ENSG00000131401.7 | 1.027E-10 | 0 | -34148 | gtex_brain_putamen_basal |
| rs1405655 | 19 | 50882619 | NAPSB | ENSG00000131401.7 | 1.731E-8 | 0 | -34595 | gtex_brain_putamen_basal |
| rs2303045 | 19 | 50882918 | NAPSB | ENSG00000131401.7 | 1.937E-10 | 0 | -34894 | gtex_brain_putamen_basal |
| rs4802703 | 19 | 50884885 | NAPSB | ENSG00000131401.7 | 3.1E-10 | 0 | -36861 | gtex_brain_putamen_basal |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
No co-expressed genes in brain regions
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| TAKEDA TARGETS OF NUP98 HOXA9 FUSION 10D UP | 194 | 122 | All SZGR 2.0 genes in this pathway |
| TAKEDA TARGETS OF NUP98 HOXA9 FUSION 16D UP | 175 | 108 | All SZGR 2.0 genes in this pathway |
| RODWELL AGING KIDNEY UP | 487 | 303 | All SZGR 2.0 genes in this pathway |
| LEE RECENT THYMIC EMIGRANT | 227 | 128 | All SZGR 2.0 genes in this pathway |
| MARTENS TRETINOIN RESPONSE UP | 857 | 456 | All SZGR 2.0 genes in this pathway |
| WIERENGA STAT5A TARGETS DN | 213 | 127 | All SZGR 2.0 genes in this pathway |