Summary ?
GeneID25884
SymbolCHRDL2
SynonymsBNF1|CHL2
Descriptionchordin-like 2
ReferenceMIM:613127|HGNC:HGNC:24168|Ensembl:ENSG00000054938|HPRD:09881|Vega:OTTHUMG00000165623
Gene typeprotein-coding
Map location11q14
Pascal p-value0.007
eGenePutamen basal ganglia

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs65925681174275894CHRDL2ENSG00000054938.113.145E-60.01166536gtex_brain_putamen_basal
rs3976915581174276933CHRDL2ENSG00000054938.113.329E-60.01165497gtex_brain_putamen_basal
rs49440471174278090CHRDL2ENSG00000054938.113.512E-60.01164340gtex_brain_putamen_basal
rs14339691174278433CHRDL2ENSG00000054938.113.547E-60.01163997gtex_brain_putamen_basal
rs19711141174281406CHRDL2ENSG00000054938.112.567E-60.01161024gtex_brain_putamen_basal
rs79526611174281777CHRDL2ENSG00000054938.113.943E-60.01160653gtex_brain_putamen_basal
rs79372321174281910CHRDL2ENSG00000054938.113.96E-60.01160520gtex_brain_putamen_basal
rs112361541174283170CHRDL2ENSG00000054938.112.435E-60.01159260gtex_brain_putamen_basal
rs79352601174293539CHRDL2ENSG00000054938.112.525E-60.01148891gtex_brain_putamen_basal
rs669015051174295413CHRDL2ENSG00000054938.112.022E-60.01147017gtex_brain_putamen_basal
rs79347421174311051CHRDL2ENSG00000054938.112.29E-60.01131379gtex_brain_putamen_basal
rs49449161174322040CHRDL2ENSG00000054938.112.515E-60.01120390gtex_brain_putamen_basal
rs108571174353371CHRDL2ENSG00000054938.113.822E-60.0189059gtex_brain_putamen_basal
rs79350571174354783CHRDL2ENSG00000054938.113.849E-60.0187647gtex_brain_putamen_basal
rs71069841174369359CHRDL2ENSG00000054938.113.176E-60.0173071gtex_brain_putamen_basal
rs71112511174370191CHRDL2ENSG00000054938.113.78E-60.0172239gtex_brain_putamen_basal
rs71310961174370356CHRDL2ENSG00000054938.113.05E-60.0172074gtex_brain_putamen_basal
rs49449361174392514CHRDL2ENSG00000054938.113.689E-70.0149916gtex_brain_putamen_basal
rs112362151174396330CHRDL2ENSG00000054938.111.066E-60.0146100gtex_brain_putamen_basal

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
GenePearson's Correlation Spearman's Correlation
COIL0.960.95
DDX210.950.94
DHX90.950.95
WDR30.950.96
XRCC50.950.94
CCT6A0.950.94
MAPRE10.950.92
MATR30.950.95
CAPRIN10.940.94
XRN20.940.95
Top 10 negatively co-expressed genes
GenePearson's Correlation Spearman's Correlation
FXYD1-0.74-0.90
AF347015.31-0.74-0.89
HLA-F-0.73-0.82
MT-CO2-0.73-0.90
AF347015.33-0.73-0.89
AF347015.27-0.72-0.87
C5orf53-0.72-0.77
S100B-0.71-0.84
TSC22D4-0.71-0.81
MT-CYB-0.70-0.87

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
ZHOU INFLAMMATORY RESPONSE FIMA UP 544308All SZGR 2.0 genes in this pathway
BENPORATH SUZ12 TARGETS 1038678All SZGR 2.0 genes in this pathway
BENPORATH EED TARGETS 1062725All SZGR 2.0 genes in this pathway
BENPORATH ES WITH H3K27ME3 1118744All SZGR 2.0 genes in this pathway
BENPORATH PRC2 TARGETS 652441All SZGR 2.0 genes in this pathway
NIKOLSKY BREAST CANCER 11Q12 Q14 AMPLICON 15893All SZGR 2.0 genes in this pathway
MIKKELSEN MCV6 HCP WITH H3K27ME3 435318All SZGR 2.0 genes in this pathway
NOUSHMEHR GBM SILENCED BY METHYLATION 5032All SZGR 2.0 genes in this pathway
NABA SECRETED FACTORS 344197All SZGR 2.0 genes in this pathway
NABA MATRISOME ASSOCIATED 753411All SZGR 2.0 genes in this pathway
NABA MATRISOME 1028559All SZGR 2.0 genes in this pathway