Gene Page: POC1A

Summary ?
GeneID25886
SymbolPOC1A
SynonymsPIX2|SOFT|WDR51A
DescriptionPOC1 centriolar protein A
ReferenceMIM:614783|HGNC:HGNC:24488|Ensembl:ENSG00000164087|HPRD:08523|Vega:OTTHUMG00000157817
Gene typeprotein-coding
Map location3p21.2
Pascal p-value0.01
Sherlock p-value0.59
eGeneMyers' cis & trans

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs2279811chr359405935POC1A258860.15trans
rs17060560chr359406495POC1A258860.09trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
GenePearson's Correlation Spearman's Correlation
FGFR10.680.57
LATS20.660.56
COL2A10.620.18
BOC0.610.44
NOTCH20.610.64
PALLD0.610.58
HEG10.610.62
TEAD10.600.59
ANTXR10.590.61
FREM20.590.52
Top 10 negatively co-expressed genes
GenePearson's Correlation Spearman's Correlation
TTC9B-0.28-0.46
OTOA-0.27-0.31
NGB-0.27-0.32
ZFAND2A-0.25-0.35
SLC26A4-0.25-0.30
USMG5-0.24-0.38
SPHAR-0.23-0.29
ATP6V0B-0.23-0.34
C18orf32-0.23-0.43
TMEM126A-0.22-0.40

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
KINSEY TARGETS OF EWSR1 FLII FUSION UP 1278748All SZGR 2.0 genes in this pathway
LINDGREN BLADDER CANCER CLUSTER 1 DN 378231All SZGR 2.0 genes in this pathway
LINDGREN BLADDER CANCER CLUSTER 3 UP 329196All SZGR 2.0 genes in this pathway
NUYTTEN EZH2 TARGETS DN 1024594All SZGR 2.0 genes in this pathway
BENPORATH CYCLING GENES 648385All SZGR 2.0 genes in this pathway
CREIGHTON ENDOCRINE THERAPY RESISTANCE 2 473224All SZGR 2.0 genes in this pathway
MARSON BOUND BY E2F4 UNSTIMULATED 728415All SZGR 2.0 genes in this pathway
CHANG CYCLING GENES 14883All SZGR 2.0 genes in this pathway
WHITFIELD CELL CYCLE G2 M 216124All SZGR 2.0 genes in this pathway
MARTENS BOUND BY PML RARA FUSION 456287All SZGR 2.0 genes in this pathway
KASLER HDAC7 TARGETS 1 UP 194133All SZGR 2.0 genes in this pathway
ZHOU CELL CYCLE GENES IN IR RESPONSE 6HR 8549All SZGR 2.0 genes in this pathway
ZHOU CELL CYCLE GENES IN IR RESPONSE 24HR 12873All SZGR 2.0 genes in this pathway