Summary ?
GeneID25917
SymbolTHUMPD3
Synonyms-
DescriptionTHUMP domain containing 3
ReferenceHGNC:HGNC:24493|Ensembl:ENSG00000134077|HPRD:15507|Vega:OTTHUMG00000097031
Gene typeprotein-coding
Map location3p25.3
Pascal p-value0.025
Sherlock p-value0.588
eGeneCortex
Frontal Cortex BA9
Meta

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS

Section I. Genetics and epigenetics annotation


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
GenePearson's Correlation Spearman's Correlation
DCTN20.930.92
MRPL490.910.91
BRF20.910.89
PSMD30.910.89
MAD2L1BP0.910.91
AHCY0.910.91
STX50.910.90
CIAPIN10.900.89
DDOST0.900.88
ACTR1A0.900.89
Top 10 negatively co-expressed genes
GenePearson's Correlation Spearman's Correlation
AF347015.8-0.78-0.81
MT-CYB-0.76-0.81
MT-CO2-0.76-0.78
AF347015.26-0.76-0.81
AF347015.27-0.75-0.80
AF347015.33-0.75-0.79
AF347015.15-0.75-0.80
AF347015.31-0.74-0.77
AF347015.2-0.73-0.77
AF347015.21-0.72-0.79

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
ZHOU INFLAMMATORY RESPONSE LIVE DN 384220All SZGR 2.0 genes in this pathway
WANG LMO4 TARGETS DN 352225All SZGR 2.0 genes in this pathway
OSMAN BLADDER CANCER UP 404246All SZGR 2.0 genes in this pathway
GARGALOVIC RESPONSE TO OXIDIZED PHOSPHOLIPIDS GREEN DN 2512All SZGR 2.0 genes in this pathway
GARGALOVIC RESPONSE TO OXIDIZED PHOSPHOLIPIDS BLUE DN 6135All SZGR 2.0 genes in this pathway
KINSEY TARGETS OF EWSR1 FLII FUSION UP 1278748All SZGR 2.0 genes in this pathway
HAMAI APOPTOSIS VIA TRAIL UP 584356All SZGR 2.0 genes in this pathway
LASTOWSKA NEUROBLASTOMA COPY NUMBER DN 800473All SZGR 2.0 genes in this pathway
LIU COMMON CANCER GENES 7947All SZGR 2.0 genes in this pathway
ZHANG RESPONSE TO IKK INHIBITOR AND TNF DN 10364All SZGR 2.0 genes in this pathway
NOUZOVA TRETINOIN AND H4 ACETYLATION 14385All SZGR 2.0 genes in this pathway
MARSON BOUND BY FOXP3 STIMULATED 1022619All SZGR 2.0 genes in this pathway
MILI PSEUDOPODIA HAPTOTAXIS UP 518299All SZGR 2.0 genes in this pathway
MARTENS TRETINOIN RESPONSE DN 841431All SZGR 2.0 genes in this pathway
STAMBOLSKY TARGETS OF MUTATED TP53 UP 4935All SZGR 2.0 genes in this pathway
LEE BMP2 TARGETS DN 882538All SZGR 2.0 genes in this pathway
LIM MAMMARY STEM CELL DN 428246All SZGR 2.0 genes in this pathway