Gene Page: THUMPD3
Summary ?
GeneID | 25917 |
Symbol | THUMPD3 |
Synonyms | - |
Description | THUMP domain containing 3 |
Reference | HGNC:HGNC:24493|Ensembl:ENSG00000134077|HPRD:15507|Vega:OTTHUMG00000097031 |
Gene type | protein-coding |
Map location | 3p25.3 |
Pascal p-value | 0.025 |
Sherlock p-value | 0.588 |
eGene | Cortex Frontal Cortex BA9 Meta |
Gene in Data Sources
Gene set name | Method of gene set | Description | Info |
---|---|---|---|
CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
Top 10 positively co-expressed genes | ||
Gene | Pearson's Correlation | Spearman's Correlation |
DCTN2 | 0.93 | 0.92 |
MRPL49 | 0.91 | 0.91 |
BRF2 | 0.91 | 0.89 |
PSMD3 | 0.91 | 0.89 |
MAD2L1BP | 0.91 | 0.91 |
AHCY | 0.91 | 0.91 |
STX5 | 0.91 | 0.90 |
CIAPIN1 | 0.90 | 0.89 |
DDOST | 0.90 | 0.88 |
ACTR1A | 0.90 | 0.89 |
Top 10 negatively co-expressed genes | ||
Gene | Pearson's Correlation | Spearman's Correlation |
AF347015.8 | -0.78 | -0.81 |
MT-CYB | -0.76 | -0.81 |
MT-CO2 | -0.76 | -0.78 |
AF347015.26 | -0.76 | -0.81 |
AF347015.27 | -0.75 | -0.80 |
AF347015.33 | -0.75 | -0.79 |
AF347015.15 | -0.75 | -0.80 |
AF347015.31 | -0.74 | -0.77 |
AF347015.2 | -0.73 | -0.77 |
AF347015.21 | -0.72 | -0.79 |
Section V. Pathway annotation
Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
---|---|---|---|
ZHOU INFLAMMATORY RESPONSE LIVE DN | 384 | 220 | All SZGR 2.0 genes in this pathway |
WANG LMO4 TARGETS DN | 352 | 225 | All SZGR 2.0 genes in this pathway |
OSMAN BLADDER CANCER UP | 404 | 246 | All SZGR 2.0 genes in this pathway |
GARGALOVIC RESPONSE TO OXIDIZED PHOSPHOLIPIDS GREEN DN | 25 | 12 | All SZGR 2.0 genes in this pathway |
GARGALOVIC RESPONSE TO OXIDIZED PHOSPHOLIPIDS BLUE DN | 61 | 35 | All SZGR 2.0 genes in this pathway |
KINSEY TARGETS OF EWSR1 FLII FUSION UP | 1278 | 748 | All SZGR 2.0 genes in this pathway |
HAMAI APOPTOSIS VIA TRAIL UP | 584 | 356 | All SZGR 2.0 genes in this pathway |
LASTOWSKA NEUROBLASTOMA COPY NUMBER DN | 800 | 473 | All SZGR 2.0 genes in this pathway |
LIU COMMON CANCER GENES | 79 | 47 | All SZGR 2.0 genes in this pathway |
ZHANG RESPONSE TO IKK INHIBITOR AND TNF DN | 103 | 64 | All SZGR 2.0 genes in this pathway |
NOUZOVA TRETINOIN AND H4 ACETYLATION | 143 | 85 | All SZGR 2.0 genes in this pathway |
MARSON BOUND BY FOXP3 STIMULATED | 1022 | 619 | All SZGR 2.0 genes in this pathway |
MILI PSEUDOPODIA HAPTOTAXIS UP | 518 | 299 | All SZGR 2.0 genes in this pathway |
MARTENS TRETINOIN RESPONSE DN | 841 | 431 | All SZGR 2.0 genes in this pathway |
STAMBOLSKY TARGETS OF MUTATED TP53 UP | 49 | 35 | All SZGR 2.0 genes in this pathway |
LEE BMP2 TARGETS DN | 882 | 538 | All SZGR 2.0 genes in this pathway |
LIM MAMMARY STEM CELL DN | 428 | 246 | All SZGR 2.0 genes in this pathway |