Gene Page: TAS2R40
Summary ?
| GeneID | 259286 |
| Symbol | TAS2R40 |
| Synonyms | GPR60|T2R40|T2R58 |
| Description | taste 2 receptor member 40 |
| Reference | MIM:613964|HGNC:HGNC:18885|Ensembl:ENSG00000221937|HPRD:18150|Vega:OTTHUMG00000152638 |
| Gene type | protein-coding |
| Map location | 7q34 |
| Pascal p-value | 0.01 |
| eGene | Myers' cis & trans |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS | |
| Expression | Meta-analysis of gene expression | P value: 1.932 |
Section I. Genetics and epigenetics annotation
eQTL annotation
| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs461218 | chr5 | 73410191 | TAS2R40 | 259286 | 0.12 | trans | ||
| rs2937774 | chr5 | 73420816 | TAS2R40 | 259286 | 0.14 | trans |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
No co-expressed genes in brain regions
Section III. Gene Ontology annotation
| Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
|---|---|---|---|---|
| GO:0004872 | receptor activity | IEA | - | |
| GO:0004930 | G-protein coupled receptor activity | IEA | - | |
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
| GO:0007186 | G-protein coupled receptor protein signaling pathway | IEA | - | |
| GO:0007165 | signal transduction | IEA | - | |
| GO:0050896 | response to stimulus | IEA | - | |
| GO:0050909 | sensory perception of taste | IEA | - | |
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
| GO:0016020 | membrane | IEA | - | |
| GO:0016021 | integral to membrane | IEA | - |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| KEGG TASTE TRANSDUCTION | 52 | 28 | All SZGR 2.0 genes in this pathway |
| MIKKELSEN MCV6 LCP WITH H3K27ME3 | 29 | 11 | All SZGR 2.0 genes in this pathway |