Gene Page: GAPDH

Summary
GeneID  2597
Symbol  GAPDH
Synonyms  G3PD|GAPD|MGC88685
Description  glyceraldehyde-3-phosphate dehydrogenase
See related  HGNC:4141|MIM:138400|Ensembl:ENSG00000111640|HPRD:00713|
Locus tag  -
Gene type  protein-coding
Map location  12p13
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenic, schizophrenia]Click to show detail
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.6677 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003824catalytic activityIEA-
GO:0005488bindingIEA-
GO:0005515protein bindingIPI17540579 
GO:0004365glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activityIEA-
GO:0004365glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activityNAS3170585 |7030790 
GO:0016491oxidoreductase activityIEA-
GO:0051287NAD bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006096glycolysisNAS-
GO:0006006glucose metabolic processIEA-
GO:0008152metabolic processIEA-
GO:0055114oxidation reductionIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005737cytoplasmNAS-
GO:0016020membraneIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
APPAAA | ABETA | ABPP | AD1 | APPI | CTFgamma | CVAP | PN2amyloid beta (A4) precursor protein-HPRD8473906 
ARAIS | DHTR | HUMARA | KD | NR3C4 | SBMA | SMAX1 | TFMandrogen receptor-HPRD,BioGRID8872471 
ARL15ARFRP2 | FLJ20051ADP-ribosylation factor-like 15Two-hybridBioGRID16169070 
ATXN1ATX1 | D6S504E | SCA1ataxin 1-HPRD,BioGRID8872471 
BPGM-2,3-bisphosphoglycerate mutase-HPRD9308888 
BTBD2-BTB (POZ) domain containing 2Two-hybridBioGRID16169070 
DYNLL1DLC1 | DLC8 | DNCL1 | DNCLC1 | LC8 | LC8a | MGC126137 | MGC126138 | PIN | hdlc1dynein, light chain, LC8-type 1-HPRD14760703 
GAPDHG3PD | GAPD | MGC88685glyceraldehyde-3-phosphate dehydrogenase-HPRD10617673 
GRM1GPRC1A | GRM1A | MGLUR1 | MGLUR1A | mGlu1glutamate receptor, metabotropic 1-HPRD9886087 
HBXIPMGC71071 | XIPhepatitis B virus x interacting proteinTwo-hybridBioGRID16169070 
HTTHD | IT15huntingtin-HPRD,BioGRID8612237 
LAMA4DKFZp686D23145 | LAMA3 | LAMA4*-1laminin, alpha 4Two-hybridBioGRID16169070 
NPATE14nuclear protein, ataxia-telangiectasia locusAffinity Capture-WesternBioGRID12887926 
PAFAH1B3-platelet-activating factor acetylhydrolase, isoform Ib, gamma subunit 29kDaTwo-hybridBioGRID16169070 
PCDHA4CNR1 | CNRN1 | CRNR1 | MGC138307 | MGC142169 | PCDH-ALPHA4protocadherin alpha 4Two-hybridBioGRID16169070 
PDIA2PDA2 | PDI | PDIP | PDIRprotein disulfide isomerase family A, member 2-HPRD,BioGRID11488911 
PGK1MGC117307 | MGC142128 | MGC8947 | MIG10 | PGKAphosphoglycerate kinase 1-HPRD,BioGRID8075252 
PLD2-phospholipase D2-HPRD,BioGRID12753082 
POU2F1OCT1 | OTF1POU class 2 homeobox 1Affinity Capture-Western
Reconstituted Complex		BioGRID12887926 
POU2F2OCT2 | OTF2 | Oct-2POU class 2 homeobox 2Reconstituted ComplexBioGRID12887926 
PRDX1MSP23 | NKEFA | PAG | PAGA | PAGB | PRX1 | PRXI | TDPX2peroxiredoxin 1Two-hybridBioGRID16169070 
PRKCIDXS1179E | MGC26534 | PKCI | nPKC-iotaprotein kinase C, iota-HPRD,BioGRID11724794 
PRKG1CGKI | DKFZp686K042 | FLJ36117 | MGC71944 | PGK | PKG | PRKG1B | PRKGR1B | cGKI-BETA | cGKI-alphaprotein kinase, cGMP-dependent, type IAffinity Capture-WesternBioGRID9308888 
PSMD11MGC3844 | Rpn6 | S9 | p44.5proteasome (prosome, macropain) 26S subunit, non-ATPase, 11Two-hybridBioGRID16169070 
QRICH2DKFZp434P0316glutamine rich 2Affinity Capture-MSBioGRID17353931 
RPA2REPA2 | RPA32replication protein A2, 32kDaTwo-hybridBioGRID16169070 
S100A62A9 | 5B10 | CABP | CACY | PRAS100 calcium binding protein A6-HPRD1999197 
SERPINB9CAP-3 | CAP3 | PI9serpin peptidase inhibitor, clade B (ovalbumin), member 9Two-hybridBioGRID16169070 
SLC2A1DYT17 | DYT18 | GLUT | GLUT1 | MGC141895 | MGC141896 | PEDsolute carrier family 2 (facilitated glucose transporter), member 1-HPRD,BioGRID2394733 
STIP1HOP | IEF-SSP-3521 | P60 | STI1 | STI1Lstress-induced-phosphoprotein 1Affinity Capture-WesternBioGRID12887926 
SYNCRIPGRY-RBP | HNRPQ1 | NSAP1 | RP1-3J17.2 | dJ3J17.2 | hnRNP-Q | pp68synaptotagmin binding, cytoplasmic RNA interacting proteinNSAP-1 interacts with GAPDH.BIND15479637 
TK1TK2thymidine kinase 1, solubleTwo-hybridBioGRID16169070 
TXNDKFZp686B1993 | MGC61975 | TRX | TRX1thioredoxinAffinity Capture-MSBioGRID17353931 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_GLYCOLYSIS_GLUCONEOGENESIS 6241All SZGR genes in this pathway
KEGG_ALZHEIMERS_DISEASE 169110All SZGR genes in this pathway
BIOCARTA_MTA3_PATHWAY 1910All SZGR genes in this pathway
BIOCARTA_GLYCOLYSIS_PATHWAY 109All SZGR genes in this pathway
WNT_SIGNALING 8971All SZGR genes in this pathway
PID_MYC_ACTIV_PATHWAY 7962All SZGR genes in this pathway
REACTOME_GLYCOLYSIS 2918All SZGR genes in this pathway
REACTOME_GLUCONEOGENESIS 3421All SZGR genes in this pathway
REACTOME_METABOLISM_OF_CARBOHYDRATES 247154All SZGR genes in this pathway
REACTOME_GLUCOSE_METABOLISM 6942All SZGR genes in this pathway
WINTER_HYPOXIA_UP 9257All SZGR genes in this pathway
KORKOLA_EMBRYONAL_CARCINOMA_UP 4127All SZGR genes in this pathway
KORKOLA_YOLK_SAC_TUMOR_UP 2014All SZGR genes in this pathway
KORKOLA_CHORIOCARCINOMA_UP 65All SZGR genes in this pathway
KORKOLA_SEMINOMA_UP 4427All SZGR genes in this pathway
CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_DN 663425All SZGR genes in this pathway
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_DN 11679All SZGR genes in this pathway
RHEIN_ALL_GLUCOCORTICOID_THERAPY_DN 362238All SZGR genes in this pathway
TIEN_INTESTINE_PROBIOTICS_2HR_UP 2719All SZGR genes in this pathway
TIEN_INTESTINE_PROBIOTICS_6HR_UP 5534All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_DN 1375806All SZGR genes in this pathway
ENK_UV_RESPONSE_KERATINOCYTE_DN 485334All SZGR genes in this pathway
CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_CDC25_UP 5839All SZGR genes in this pathway
BERENJENO_TRANSFORMED_BY_RHOA_UP 536340All SZGR genes in this pathway
DACOSTA_LOW_DOSE_UV_RESPONSE_VIA_ERCC3_XPCS_DN 96All SZGR genes in this pathway
DIRMEIER_LMP1_RESPONSE_LATE_DN 3222All SZGR genes in this pathway
PUJANA_BRCA1_PCC_NETWORK 16521023All SZGR genes in this pathway
PUJANA_ATM_PCC_NETWORK 1442892All SZGR genes in this pathway
ALCALA_APOPTOSIS 8860All SZGR genes in this pathway
GROSS_HIF1A_TARGETS_DN 2515All SZGR genes in this pathway
GROSS_HYPOXIA_VIA_HIF1A_DN 11078All SZGR genes in this pathway
BENPORATH_MYC_TARGETS_WITH_EBOX 230156All SZGR genes in this pathway
MORI_PRE_BI_LYMPHOCYTE_UP 8054All SZGR genes in this pathway
MORI_SMALL_PRE_BII_LYMPHOCYTE_DN 7652All SZGR genes in this pathway
SHIPP_DLBCL_CURED_VS_FATAL_DN 4530All SZGR genes in this pathway
GNATENKO_PLATELET_SIGNATURE 4828All SZGR genes in this pathway
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_UP 8758All SZGR genes in this pathway
FLECHNER_PBL_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN 5135All SZGR genes in this pathway
GALINDO_IMMUNE_RESPONSE_TO_ENTEROTOXIN 8567All SZGR genes in this pathway
FERRANDO_T_ALL_WITH_MLL_ENL_FUSION_DN 8757All SZGR genes in this pathway
MUNSHI_MULTIPLE_MYELOMA_UP 8152All SZGR genes in this pathway
KUMAR_TARGETS_OF_MLL_AF9_FUSION 405264All SZGR genes in this pathway
TRAYNOR_RETT_SYNDROM_UP 4533All SZGR genes in this pathway
BRACHAT_RESPONSE_TO_METHOTREXATE_DN 2719All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN 1237837All SZGR genes in this pathway
HARRIS_HYPOXIA 8164All SZGR genes in this pathway
NATSUME_RESPONSE_TO_INTERFERON_BETA_DN 5233All SZGR genes in this pathway
MACLACHLAN_BRCA1_TARGETS_UP 2116All SZGR genes in this pathway
BRACHAT_RESPONSE_TO_CAMPTOTHECIN_DN 4631All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_6HR_UP 7148All SZGR genes in this pathway
SEMENZA_HIF1_TARGETS 3632All SZGR genes in this pathway
ZHONG_SECRETOME_OF_LUNG_CANCER_AND_ENDOTHELIUM 6647All SZGR genes in this pathway
MARTINEZ_RB1_TARGETS_UP 673430All SZGR genes in this pathway
MARTINEZ_TP53_TARGETS_UP 602364All SZGR genes in this pathway
MARTINEZ_RB1_AND_TP53_TARGETS_UP 601369All SZGR genes in this pathway
RIZKI_TUMOR_INVASIVENESS_3D_DN 270181All SZGR genes in this pathway
DAIRKEE_CANCER_PRONE_RESPONSE_BPA_E2 11865All SZGR genes in this pathway
HONMA_DOCETAXEL_RESISTANCE 3423All SZGR genes in this pathway
WHITEFORD_PEDIATRIC_CANCER_MARKERS 11663All SZGR genes in this pathway
GRADE_COLON_CANCER_UP 871505All SZGR genes in this pathway
WEST_ADRENOCORTICAL_TUMOR_UP 294199All SZGR genes in this pathway
WINTER_HYPOXIA_METAGENE 242168All SZGR genes in this pathway
MOOTHA_PGC 420269All SZGR genes in this pathway
GOLDRATH_ANTIGEN_RESPONSE 346192All SZGR genes in this pathway
VANTVEER_BREAST_CANCER_ESR1_DN 240153All SZGR genes in this pathway
SWEET_LUNG_CANCER_KRAS_UP 491316All SZGR genes in this pathway
SHEDDEN_LUNG_CANCER_POOR_SURVIVAL_A6 456285All SZGR genes in this pathway
HSIAO_HOUSEKEEPING_GENES 389245All SZGR genes in this pathway
NGO_MALIGNANT_GLIOMA_1P_LOH 1713All SZGR genes in this pathway
DANG_MYC_TARGETS_UP 143100All SZGR genes in this pathway
DANG_BOUND_BY_MYC 1103714All SZGR genes in this pathway
CHANDRAN_METASTASIS_UP 221135All SZGR genes in this pathway
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_14 14386All SZGR genes in this pathway
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_16 7947All SZGR genes in this pathway
KIM_ALL_DISORDERS_OLIGODENDROCYTE_NUMBER_CORR_UP 756494All SZGR genes in this pathway
GREGORY_SYNTHETIC_LETHAL_WITH_IMATINIB 14583All SZGR genes in this pathway
WANG_ADIPOGENIC_GENES_REPRESSED_BY_SIRT1 2821All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_A 898516All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_D 280158All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_LATE 1137655All SZGR genes in this pathway
WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_8D 882506All SZGR genes in this pathway
KRIEG_HYPOXIA_NOT_VIA_KDM3A 770480All SZGR genes in this pathway
PECE_MAMMARY_STEM_CELL_UP 14675All SZGR genes in this pathway
HOLLEMAN_PREDNISOLONE_RESISTANCE_B_ALL_DN 128All SZGR genes in this pathway


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