Gene Page: ULK3
Summary ?
GeneID | 25989 |
Symbol | ULK3 |
Synonyms | - |
Description | unc-51 like kinase 3 |
Reference | MIM:613472|HGNC:HGNC:19703|Ensembl:ENSG00000140474|HPRD:15609|Vega:OTTHUMG00000173020 |
Gene type | protein-coding |
Map location | 15q24.1 |
Pascal p-value | 0.018 |
Sherlock p-value | 0.315 |
eGene | Meta |
Gene in Data Sources
Gene set name | Method of gene set | Description | Info |
---|---|---|---|
CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
Top 10 positively co-expressed genes | ||
Gene | Pearson's Correlation | Spearman's Correlation |
WRNIP1 | 0.90 | 0.88 |
ARF1 | 0.89 | 0.88 |
FARSA | 0.88 | 0.86 |
EID2 | 0.87 | 0.86 |
CTBP1 | 0.87 | 0.87 |
EPN1 | 0.86 | 0.85 |
PANK4 | 0.86 | 0.85 |
LONP1 | 0.86 | 0.84 |
IRF2BP1 | 0.86 | 0.86 |
LDOC1 | 0.86 | 0.84 |
Top 10 negatively co-expressed genes | ||
Gene | Pearson's Correlation | Spearman's Correlation |
MT-CO2 | -0.72 | -0.66 |
AF347015.21 | -0.71 | -0.67 |
NOSTRIN | -0.70 | -0.69 |
AF347015.33 | -0.70 | -0.65 |
AF347015.31 | -0.69 | -0.66 |
AF347015.8 | -0.69 | -0.65 |
AF347015.2 | -0.67 | -0.62 |
MT-CYB | -0.66 | -0.63 |
AP002478.3 | -0.66 | -0.66 |
FXYD1 | -0.65 | -0.62 |
Section V. Pathway annotation
Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
---|---|---|---|
KEGG REGULATION OF AUTOPHAGY | 35 | 30 | All SZGR 2.0 genes in this pathway |
KEGG MTOR SIGNALING PATHWAY | 52 | 40 | All SZGR 2.0 genes in this pathway |
CHARAFE BREAST CANCER LUMINAL VS MESENCHYMAL UP | 450 | 256 | All SZGR 2.0 genes in this pathway |
SENESE HDAC3 TARGETS DN | 536 | 332 | All SZGR 2.0 genes in this pathway |
OZEN MIR125B1 TARGETS | 25 | 15 | All SZGR 2.0 genes in this pathway |
FIRESTEIN PROLIFERATION | 175 | 125 | All SZGR 2.0 genes in this pathway |
WIERENGA STAT5A TARGETS DN | 213 | 127 | All SZGR 2.0 genes in this pathway |