Gene Page: PTCD1
Summary ?
GeneID | 26024 |
Symbol | PTCD1 |
Synonyms | - |
Description | pentatricopeptide repeat domain 1 |
Reference | MIM:614774|HGNC:HGNC:22198|Ensembl:ENSG00000106246|HPRD:11463|Vega:OTTHUMG00000154600 |
Gene type | protein-coding |
Map location | 7q22.1 |
Sherlock p-value | 4.889E-4 |
Support | Ascano FMRP targets |
Gene in Data Sources
Gene set name | Method of gene set | Description | Info |
---|---|---|---|
CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
Top 10 positively co-expressed genes | ||
Gene | Pearson's Correlation | Spearman's Correlation |
NRBP1 | 0.92 | 0.93 |
EIF2B5 | 0.92 | 0.91 |
TBCD | 0.91 | 0.92 |
NOP56 | 0.91 | 0.90 |
EIF4ENIF1 | 0.90 | 0.89 |
MARS | 0.90 | 0.89 |
TUBGCP2 | 0.90 | 0.91 |
ATG4B | 0.90 | 0.88 |
ZNF174 | 0.90 | 0.88 |
LRSAM1 | 0.89 | 0.88 |
Top 10 negatively co-expressed genes | ||
Gene | Pearson's Correlation | Spearman's Correlation |
MT-CO2 | -0.86 | -0.83 |
AF347015.31 | -0.85 | -0.82 |
AF347015.8 | -0.84 | -0.83 |
AF347015.33 | -0.84 | -0.81 |
AF347015.27 | -0.83 | -0.82 |
MT-CYB | -0.83 | -0.79 |
AF347015.2 | -0.82 | -0.82 |
AF347015.21 | -0.82 | -0.85 |
AF347015.15 | -0.81 | -0.80 |
AF347015.26 | -0.78 | -0.80 |
Section V. Pathway annotation
Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
---|---|---|---|
WANG CLIM2 TARGETS UP | 269 | 146 | All SZGR 2.0 genes in this pathway |
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 8D DN | 205 | 127 | All SZGR 2.0 genes in this pathway |
RODRIGUES THYROID CARCINOMA POORLY DIFFERENTIATED DN | 805 | 505 | All SZGR 2.0 genes in this pathway |
NIKOLSKY BREAST CANCER 7Q21 Q22 AMPLICON | 76 | 33 | All SZGR 2.0 genes in this pathway |
BRUINS UVC RESPONSE VIA TP53 GROUP A | 898 | 516 | All SZGR 2.0 genes in this pathway |
BRUINS UVC RESPONSE MIDDLE | 98 | 56 | All SZGR 2.0 genes in this pathway |