SZGR2

Summary ?

GeneID	26824
Symbol	RNU11
Synonyms	RNU11-1\|U11
Description	RNA, U11 small nuclear
Reference	HGNC:HGNC:10108\|Ensembl:ENSG00000270103\|Ensembl:ENSG00000274978\|
Gene type	snRNA
Map location	1p35.3
Pascal p-value	0.005

Gene in Data Sources

Gene set name	Method of gene set	Description	Info
CV:PGCnp	Genome-wide Association Study	GWAS

Section I. Genetics and epigenetics annotation

Section II. Transcriptome annotation

General gene expression (GTEx)

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
Gene	Pearson's Correlation	Spearman's Correlation
KTI12	0.92	0.89
KBTBD4	0.92	0.88
FADD	0.92	0.89
RUVBL2	0.90	0.91
CLP1	0.90	0.88
PSMD3	0.90	0.88
RRP9	0.90	0.90
ARMC6	0.90	0.89
TBCC	0.90	0.87
BYSL	0.90	0.89

Top 10 negatively co-expressed genes
Gene	Pearson's Correlation	Spearman's Correlation
MT-CO2	-0.74	-0.79
AF347015.33	-0.73	-0.80
AF347015.31	-0.73	-0.79
AF347015.8	-0.73	-0.79
MT-CYB	-0.72	-0.79
AF347015.27	-0.72	-0.79
AF347015.15	-0.70	-0.78
AF347015.2	-0.69	-0.76
AF347015.21	-0.69	-0.79
AF347015.26	-0.68	-0.77

Section IV. Protein-protein interaction annotation

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
DHX15	DBP1 \| DDX15 \| HRH2 \| PRP43 \| PRPF43 \| PrPp43p	DEAH (Asp-Glu-Ala-His) box polypeptide 15	Affinity Capture-MS	BioGRID	15146077
EFTUD2	DKFZp686E24196 \| FLJ44695 \| KIAA0031 \| Snrp116 \| Snu114 \| U5-116KD	elongation factor Tu GTP binding domain containing 2	Affinity Capture-MS	BioGRID	15146077
PDCD7	ES18 \| HES18 \| MGC22015	programmed cell death 7	Affinity Capture-MS	BioGRID	15146077
PHF5A	INI \| MGC1346 \| SF3b14b \| bK223H9.2	PHD finger protein 5A	Affinity Capture-MS	BioGRID	15146077
PRKRIP1	C114 \| FLJ13902 \| FLJ40957	PRKR interacting protein 1 (IL11 inducible)	Affinity Capture-MS	BioGRID	15146077
PRPF6	ANT-1 \| C20orf14 \| TOM \| U5-102K \| hPrp6	PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae)	Affinity Capture-MS	BioGRID	15146077
PRPF8	HPRP8 \| PRP8 \| PRPC8 \| RP13	PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae)	Affinity Capture-MS	BioGRID	15146077
RNPC3	FLJ20008 \| FLJ25070 \| KIAA183 \| RBM40 \| RNP	RNA-binding region (RNP1, RRM) containing 3	Affinity Capture-MS	BioGRID	15146077
SF3B1	PRP10 \| PRPF10 \| SAP155 \| SF3b155	splicing factor 3b, subunit 1, 155kDa	Affinity Capture-MS	BioGRID	15146077
SF3B2	SAP145 \| SF3B145 \| SF3b1 \| SF3b150	splicing factor 3b, subunit 2, 145kDa	Affinity Capture-MS	BioGRID	15146077
SF3B3	KIAA0017 \| RSE1 \| SAP130 \| SF3b130 \| STAF130	splicing factor 3b, subunit 3, 130kDa	Affinity Capture-MS	BioGRID	15146077
SF3B4	MGC10828 \| SAP49 \| SF3b49	splicing factor 3b, subunit 4, 49kDa	Affinity Capture-MS	BioGRID	15146077
SNRNP200	ASCC3L1 \| BRR2 \| HELIC2 \| U5-200KD	small nuclear ribonucleoprotein 200kDa (U5)	Affinity Capture-MS	BioGRID	15146077
SNRNP25	C16orf33 \| FLJ22940	small nuclear ribonucleoprotein 25kDa (U11/U12)	Affinity Capture-MS	BioGRID	15146077
SNRNP35	HM-1 \| MGC138160 \| U1SNRNPBP	small nuclear ribonucleoprotein 35kDa (U11/U12)	Affinity Capture-MS	BioGRID	15146077
SNRNP48	C6orf151 \| FLJ32234 \| MGC138904 \| MGC138905 \| dJ336K20B.1 \| dJ512B11.2	small nuclear ribonucleoprotein 48kDa (U11/U12)	Affinity Capture-MS	BioGRID	15146077
SNRPD1	HsT2456 \| SMD1 \| SNRPD	small nuclear ribonucleoprotein D1 polypeptide 16kDa	Affinity Capture-MS	BioGRID	15146077
SNRPD2	SMD2 \| SNRPD1	small nuclear ribonucleoprotein D2 polypeptide 16.5kDa	Affinity Capture-MS	BioGRID	15146077
SNRPD3	SMD3	small nuclear ribonucleoprotein D3 polypeptide 18kDa	Affinity Capture-MS	BioGRID	15146077
SNRPG	MGC117317 \| SMG	small nuclear ribonucleoprotein polypeptide G	Affinity Capture-MS	BioGRID	15146077
TOE1	FLJ13949	target of EGR1, member 1 (nuclear)	Affinity Capture-MS	BioGRID	15146077
U2AF1	DKFZp313J1712 \| FP793 \| RN \| RNU2AF1 \| U2AF35 \| U2AFBP	U2 small nuclear RNA auxiliary factor 1	Affinity Capture-MS	BioGRID	15146077
YBX1	BP-8 \| CSDA2 \| CSDB \| DBPB \| MDR-NF1 \| MGC104858 \| MGC110976 \| MGC117250 \| NSEP-1 \| NSEP1 \| YB-1 \| YB1	Y box binding protein 1	Affinity Capture-MS	BioGRID	15146077
ZCRB1	MADP-1 \| MADP1 \| MGC26805 \| RBM36 \| ZCCHC19	zinc finger CCHC-type and RNA binding motif 1	Affinity Capture-MS	BioGRID	15146077
ZMAT5	-	zinc finger, matrin type 5	Affinity Capture-MS	BioGRID	15146077

Section V. Pathway annotation

Pathway name	Pathway size	# SZGR 2.0 genes in pathway	Info
ZWANG TRANSIENTLY UP BY 2ND EGF PULSE ONLY	1725	838	All SZGR 2.0 genes in this pathway