Summary ?
GeneID27077
SymbolB9D1
SynonymsB9|EPPB9|MKS9|MKSR1
DescriptionB9 protein domain 1
ReferenceMIM:614144|HGNC:HGNC:24123|Ensembl:ENSG00000108641|HPRD:16866|Vega:OTTHUMG00000059586
Gene typeprotein-coding
Map location17p11.2
Pascal p-value2.33E-5
Sherlock p-value0.603
Fetal beta-1.612
DMG1 (# studies)
eGeneMyers' cis & trans

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS
DMG:Wockner_2014Genome-wide DNA methylation analysisThis dataset includes 4641 differentially methylated probes corresponding to 2929 unique genes between schizophrenia patients (n=24) and controls (n=24). 3

Section I. Genetics and epigenetics annotation

@Differentially methylated gene

ProbeChromosomePositionNearest geneP (dis)Beta (dis)FDR (dis)Study
cg110117741719266179B9D11.527E-4-0.290.032DMG:Wockner_2014
cg202722871719247905MIR1180;B9D12.576E-40.5490.038DMG:Wockner_2014
cg191576471719247897MIR1180;B9D13.988E-40.4790.044DMG:Wockner_2014

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs10025818chr442364050B9D1270770.15trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
GenePearson's Correlation Spearman's Correlation
SENP60.960.96
PCM10.950.97
ARID4B0.950.96
AHCTF10.950.96
SR1400.950.97
USP480.950.96
NOL80.940.96
SMEK10.940.96
TTC370.940.95
BRWD10.930.93
Top 10 negatively co-expressed genes
GenePearson's Correlation Spearman's Correlation
AF347015.31-0.78-0.86
MT-CO2-0.77-0.85
IFI27-0.77-0.86
FXYD1-0.76-0.84
HIGD1B-0.75-0.86
ENHO-0.75-0.88
AF347015.27-0.74-0.81
AF347015.33-0.74-0.80
AF347015.8-0.72-0.82
MT-CYB-0.72-0.80

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
SENGUPTA NASOPHARYNGEAL CARCINOMA DN 349157All SZGR 2.0 genes in this pathway
DODD NASOPHARYNGEAL CARCINOMA UP 1821933All SZGR 2.0 genes in this pathway
RODRIGUES THYROID CARCINOMA ANAPLASTIC DN 537339All SZGR 2.0 genes in this pathway
NIKOLSKY BREAST CANCER 17P11 AMPLICON 108All SZGR 2.0 genes in this pathway
PAL PRMT5 TARGETS UP 203135All SZGR 2.0 genes in this pathway
BROWNE HCMV INFECTION 24HR DN 148102All SZGR 2.0 genes in this pathway
BURTON ADIPOGENESIS 8 8657All SZGR 2.0 genes in this pathway
SMID BREAST CANCER LUMINAL B UP 172109All SZGR 2.0 genes in this pathway
SMID BREAST CANCER BASAL DN 701446All SZGR 2.0 genes in this pathway
CAIRO HEPATOBLASTOMA CLASSES UP 605377All SZGR 2.0 genes in this pathway
YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 13 172107All SZGR 2.0 genes in this pathway
BROWNE HCMV INFECTION 4HR DN 254158All SZGR 2.0 genes in this pathway
BRUINS UVC RESPONSE EARLY LATE 317190All SZGR 2.0 genes in this pathway