Gene Page: GLB1

Summary
GeneID  2720
Symbol  GLB1
Synonyms  EBP|ELNR1
Description  galactosidase, beta 1
See related  HGNC:4298|MIM:611458|Ensembl:ENSG00000170266|HPRD:01975|
Locus tag  -
Gene type  protein-coding
Map location  3p21.33
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.006 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
TGIF20.910.75
ITPRIP0.900.66
LIPG0.900.52
CELSR10.900.46
NOTCH10.890.83
TP530.890.70
PTBP10.890.81
SFRP10.880.62
CDK20.870.59
TEAD20.870.46
Top 10 negatively co-expressed genes
ADAP1-0.34-0.29
C5orf53-0.34-0.38
FXYD7-0.33-0.30
RAMP3-0.33-0.24
LGI1-0.32-0.24
CKMT1B-0.32-0.23
ASPHD1-0.31-0.23
CMTM8-0.31-0.25
NPM2-0.31-0.29
SLC9A3R2-0.31-0.06
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI17353931 
GO:0004565beta-galactosidase activityTAS3143362 
GO:0016798hydrolase activity, acting on glycosyl bondsIEA-
GO:0043169cation bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0005975carbohydrate metabolic processIEA-
GO:0008152metabolic processIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005737cytoplasmIEA-
GO:0005764lysosomeIEA-
GO:0009341beta-galactosidase complexIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CTNNBIP1ICAT | MGC15093catenin, beta interacting protein 1Affinity Capture-MSBioGRID17353931 
NEU1FLJ93471 | NANH | NEU | SIAL1sialidase 1 (lysosomal sialidase)-HPRD,BioGRID3102233 |3922758 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_GALACTOSE_METABOLISM 2622All SZGR genes in this pathway
KEGG_OTHER_GLYCAN_DEGRADATION 1612All SZGR genes in this pathway
KEGG_GLYCOSAMINOGLYCAN_DEGRADATION 2114All SZGR genes in this pathway
KEGG_SPHINGOLIPID_METABOLISM 4026All SZGR genes in this pathway
KEGG_GLYCOSPHINGOLIPID_BIOSYNTHESIS_GANGLIO_SERIES 159All SZGR genes in this pathway
KEGG_LYSOSOME 12183All SZGR genes in this pathway
REACTOME_GLYCOSPHINGOLIPID_METABOLISM 3822All SZGR genes in this pathway
REACTOME_HS_GAG_DEGRADATION 2015All SZGR genes in this pathway
REACTOME_PHOSPHOLIPID_METABOLISM 198112All SZGR genes in this pathway
REACTOME_KERATAN_SULFATE_KERATIN_METABOLISM 3021All SZGR genes in this pathway
REACTOME_KERATAN_SULFATE_DEGRADATION 117All SZGR genes in this pathway
REACTOME_HEPARAN_SULFATE_HEPARIN_HS_GAG_METABOLISM 5233All SZGR genes in this pathway
REACTOME_GLYCOSAMINOGLYCAN_METABOLISM 11169All SZGR genes in this pathway
REACTOME_SPHINGOLIPID_METABOLISM 6940All SZGR genes in this pathway
REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 478302All SZGR genes in this pathway
REACTOME_METABOLISM_OF_CARBOHYDRATES 247154All SZGR genes in this pathway
ONKEN_UVEAL_MELANOMA_DN 526357All SZGR genes in this pathway
HEIDENBLAD_AMPLICON_12P11_12_DN 3016All SZGR genes in this pathway
MOHANKUMAR_TLX1_TARGETS_UP 414287All SZGR genes in this pathway
NUYTTEN_EZH2_TARGETS_UP 1037673All SZGR genes in this pathway
RICKMAN_TUMOR_DIFFERENTIATED_MODERATELY_VS_POORLY_UP 12171All SZGR genes in this pathway
SASAKI_ADULT_T_CELL_LEUKEMIA 176122All SZGR genes in this pathway
ZHAN_V2_LATE_DIFFERENTIATION_GENES 4534All SZGR genes in this pathway
BRUNO_HEMATOPOIESIS 6648All SZGR genes in this pathway
SESTO_RESPONSE_TO_UV_C8 7256All SZGR genes in this pathway
DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_DN 287208All SZGR genes in this pathway
CHENG_IMPRINTED_BY_ESTRADIOL 11068All SZGR genes in this pathway
ACEVEDO_LIVER_CANCER_UP 973570All SZGR genes in this pathway
CHEN_METABOLIC_SYNDROM_NETWORK 1210725All SZGR genes in this pathway
YAGI_AML_WITH_INV_16_TRANSLOCATION 422277All SZGR genes in this pathway
JOHNSTONE_PARVB_TARGETS_3_UP 430288All SZGR genes in this pathway
WAKABAYASHI_ADIPOGENESIS_PPARG_BOUND_8D 658397All SZGR genes in this pathway


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