Gene Page: GLUD2

Summary
GeneID  2747
Symbol  GLUD2
Synonyms  GDH2|GLUDP1
Description  glutamate dehydrogenase 2
See related  HGNC:4336|MIM:300144|Ensembl:ENSG00000182890|HPRD:02143|
Locus tag  -
Gene type  protein-coding
Map location  Xq24-q25
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 3 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
TRUB10.900.93
MTMR60.900.92
UHRF1BP1L0.900.91
NCKAP10.890.91
TSNAX0.880.90
UBE2W0.880.91
RPRD1A0.870.91
PPP1R20.870.90
PRKACB0.870.89
RFK0.870.88
Top 10 negatively co-expressed genes
AL022328.1-0.53-0.64
C16orf79-0.50-0.55
EIF4EBP3-0.48-0.55
MICALL2-0.47-0.53
GSDMD-0.46-0.52
AC098691.2-0.45-0.48
RAB34-0.45-0.53
ACP6-0.44-0.49
AC069281.3-0.44-0.54
GPT-0.44-0.49
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004353glutamate dehydrogenase [NAD(P)+] activityIEAglutamate (GO term level: 6)-
GO:0004352glutamate dehydrogenase activityIDAglutamate (GO term level: 6)8207021 |15578726 
GO:0005488bindingIEA-
GO:0016491oxidoreductase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006536glutamate metabolic processIDAglutamate (GO term level: 8)8207021 
GO:0006520amino acid metabolic processIEA-
GO:0055114oxidation reductionIDA8207021 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005739mitochondrionIEA-
GO:0005759mitochondrial matrixIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
GLUD2GDH2 | GLUDP1glutamate dehydrogenase 2-HPRD12054821 
TOM1L1OK/KNS-CL.3 | SRCASMtarget of myb1 (chicken)-like 1Two-hybridBioGRID16169070 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_ALANINE_ASPARTATE_AND_GLUTAMATE_METABOLISM 3226All SZGR genes in this pathway
KEGG_ARGININE_AND_PROLINE_METABOLISM 5439All SZGR genes in this pathway
KEGG_NITROGEN_METABOLISM 2316All SZGR genes in this pathway
KEGG_PROXIMAL_TUBULE_BICARBONATE_RECLAMATION 2316All SZGR genes in this pathway
PARENT_MTOR_SIGNALING_UP 567375All SZGR genes in this pathway
TURASHVILI_BREAST_NORMAL_DUCTAL_VS_LOBULAR_UP 6840All SZGR genes in this pathway
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP 1382904All SZGR genes in this pathway
OSMAN_BLADDER_CANCER_UP 404246All SZGR genes in this pathway
MULLIGHAN_NPM1_SIGNATURE_3_UP 341197All SZGR genes in this pathway
ELVIDGE_HYPOXIA_DN 14694All SZGR genes in this pathway
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN 546351All SZGR genes in this pathway
LI_WILMS_TUMOR_VS_FETAL_KIDNEY_1_UP 182119All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_DN 1237837All SZGR genes in this pathway
KAAB_HEART_ATRIUM_VS_VENTRICLE_DN 261183All SZGR genes in this pathway
DAZARD_RESPONSE_TO_UV_SCC_UP 12375All SZGR genes in this pathway
BAELDE_DIABETIC_NEPHROPATHY_DN 434302All SZGR genes in this pathway
MOOTHA_HUMAN_MITODB_6_2002 429260All SZGR genes in this pathway
MOOTHA_MITOCHONDRIA 447277All SZGR genes in this pathway
CHIANG_LIVER_CANCER_SUBCLASS_UNANNOTATED_DN 193112All SZGR genes in this pathway
WOO_LIVER_CANCER_RECURRENCE_DN 8054All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_1ST_EGF_PULSE_ONLY 1839928All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-103/107547553m8hsa-miR-103brainAGCAGCAUUGUACAGGGCUAUGA
hsa-miR-107brainAGCAGCAUUGUACAGGGCUAUCA
miR-15/16/195/424/497548554m8hsa-miR-15abrainUAGCAGCACAUAAUGGUUUGUG
hsa-miR-16brainUAGCAGCACGUAAAUAUUGGCG
hsa-miR-15bbrainUAGCAGCACAUCAUGGUUUACA
hsa-miR-195SZUAGCAGCACAGAAAUAUUGGC
hsa-miR-424CAGCAGCAAUUCAUGUUUUGAA
hsa-miR-497CAGCAGCACACUGUGGUUUGU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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