Gene Page: GML
Summary ?
GeneID | 2765 |
Symbol | GML |
Synonyms | LY6DL |
Description | glycosylphosphatidylinositol anchored molecule like |
Reference | MIM:602370|HGNC:HGNC:4375|Ensembl:ENSG00000104499|HPRD:03844|Vega:OTTHUMG00000164656 |
Gene type | protein-coding |
Map location | 8q24.3 |
Pascal p-value | 0.027 |
Gene in Data Sources
Gene set name | Method of gene set | Description | Info |
---|---|---|---|
CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
Top 10 positively co-expressed genes | ||
Gene | Pearson's Correlation | Spearman's Correlation |
TRIM32 | 0.92 | 0.93 |
VPS26B | 0.92 | 0.93 |
LASP1 | 0.92 | 0.93 |
CSNK1D | 0.92 | 0.92 |
RAB35 | 0.91 | 0.92 |
ZDHHC3 | 0.91 | 0.91 |
KIAA1191 | 0.91 | 0.91 |
CD200 | 0.91 | 0.90 |
UBQLN4 | 0.91 | 0.91 |
AMBRA1 | 0.91 | 0.91 |
Top 10 negatively co-expressed genes | ||
Gene | Pearson's Correlation | Spearman's Correlation |
MT-CO2 | -0.78 | -0.82 |
FXYD1 | -0.78 | -0.83 |
AF347015.31 | -0.77 | -0.82 |
AF347015.33 | -0.76 | -0.80 |
MT-CYB | -0.75 | -0.79 |
HIGD1B | -0.75 | -0.80 |
AF347015.8 | -0.74 | -0.81 |
S100B | -0.74 | -0.80 |
AF347015.26 | -0.73 | -0.79 |
AC021016.1 | -0.73 | -0.80 |
Section V. Pathway annotation
Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
---|---|---|---|
NIKOLSKY BREAST CANCER 8Q23 Q24 AMPLICON | 157 | 87 | All SZGR 2.0 genes in this pathway |
GERY CEBP TARGETS | 126 | 90 | All SZGR 2.0 genes in this pathway |
XU GH1 AUTOCRINE TARGETS UP | 268 | 157 | All SZGR 2.0 genes in this pathway |
ACEVEDO METHYLATED IN LIVER CANCER DN | 940 | 425 | All SZGR 2.0 genes in this pathway |
LABBE WNT3A TARGETS DN | 97 | 53 | All SZGR 2.0 genes in this pathway |
CHYLA CBFA2T3 TARGETS DN | 242 | 146 | All SZGR 2.0 genes in this pathway |
ZWANG TRANSIENTLY UP BY 2ND EGF PULSE ONLY | 1725 | 838 | All SZGR 2.0 genes in this pathway |