Summary ?
GeneID282973
SymbolJAKMIP3
SynonymsC10orf14|C10orf39|Jamip3|NECC2|bA140A10.5
DescriptionJanus kinase and microtubule interacting protein 3
ReferenceMIM:611198|HGNC:HGNC:23523|Ensembl:ENSG00000188385|HPRD:12574|Vega:OTTHUMG00000150167
Gene typeprotein-coding
Map location10q26.3
Pascal p-value0.131
Fetal beta-1.382
DMG1 (# studies)
eGeneAnterior cingulate cortex BA24
Caudate basal ganglia
Cerebellar Hemisphere
Cerebellum
Cortex
Frontal Cortex BA9
Hippocampus
Hypothalamus
Nucleus accumbens basal ganglia
Putamen basal ganglia
Meta

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS
DMG:Wockner_2014Genome-wide DNA methylation analysisThis dataset includes 4641 differentially methylated probes corresponding to 2929 unique genes between schizophrenia patients (n=24) and controls (n=24). 1

Section I. Genetics and epigenetics annotation

@Differentially methylated gene

ProbeChromosomePositionNearest geneP (dis)Beta (dis)FDR (dis)Study
cg1576862010133938604JAKMIP33.919E-40.180.043DMG:Wockner_2014

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs20034254910133952960JAKMIP3ENSG00000188385.71.61E-7034785gtex_brain_ba24
rs709645610133953469JAKMIP3ENSG00000188385.73.421E-9035294gtex_brain_ba24
rs281838710133954011JAKMIP3ENSG00000188385.75.316E-8035836gtex_brain_ba24
rs973332410133954111JAKMIP3ENSG00000188385.79.975E-8035936gtex_brain_ba24
rs263764710133954267JAKMIP3ENSG00000188385.75.188E-7036092gtex_brain_ba24
rs1159258510133955427JAKMIP3ENSG00000188385.79.044E-8037252gtex_brain_ba24
rs3523068410133956079JAKMIP3ENSG00000188385.79.468E-8037904gtex_brain_ba24
rs1224704410133956094JAKMIP3ENSG00000188385.73.575E-8037919gtex_brain_ba24
rs263762410133956675JAKMIP3ENSG00000188385.71.506E-8038500gtex_brain_ba24
rs708787110133957046JAKMIP3ENSG00000188385.73.823E-7038871gtex_brain_ba24
rs1136131410133957057JAKMIP3ENSG00000188385.73.954E-7038882gtex_brain_ba24
rs708790610133957126JAKMIP3ENSG00000188385.74.092E-7038951gtex_brain_ba24
rs95481910133957489JAKMIP3ENSG00000188385.74.947E-7039314gtex_brain_ba24
rs20034254910133952960JAKMIP3ENSG00000188385.73.476E-8034785gtex_brain_putamen_basal
rs709645610133953469JAKMIP3ENSG00000188385.73.958E-9035294gtex_brain_putamen_basal
rs281838710133954011JAKMIP3ENSG00000188385.71.314E-7035836gtex_brain_putamen_basal
rs973332410133954111JAKMIP3ENSG00000188385.74.283E-10035936gtex_brain_putamen_basal
rs263764710133954267JAKMIP3ENSG00000188385.77.995E-9036092gtex_brain_putamen_basal
rs1159258510133955427JAKMIP3ENSG00000188385.73.401E-9037252gtex_brain_putamen_basal
rs1224704410133956094JAKMIP3ENSG00000188385.73.186E-8037919gtex_brain_putamen_basal
rs263762410133956675JAKMIP3ENSG00000188385.74.08E-7038500gtex_brain_putamen_basal
rs708787110133957046JAKMIP3ENSG00000188385.77.223E-8038871gtex_brain_putamen_basal
rs1136131410133957057JAKMIP3ENSG00000188385.77.237E-8038882gtex_brain_putamen_basal
rs708790610133957126JAKMIP3ENSG00000188385.74.265E-8038951gtex_brain_putamen_basal
rs95481910133957489JAKMIP3ENSG00000188385.75.459E-8039314gtex_brain_putamen_basal

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
LASTOWSKA NEUROBLASTOMA COPY NUMBER DN 800473All SZGR 2.0 genes in this pathway
PANGAS TUMOR SUPPRESSION BY SMAD1 AND SMAD5 DN 157106All SZGR 2.0 genes in this pathway